DROME|FlyBase=FBgn0034945|UniProtKB=Q9W1E7 Q9W1E7 Dmel\CG10904 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0039316|UniProtKB=Q9VBT2 Q9VBT2 Dmel\CG11893 PTHR11012:SF12 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0053985|UniProtKB=Q2PDY7 Q2PDY7 CG17014 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0004227|UniProtKB=Q04047 Q04047 nonA PTHR23189:SF102 RNA RECOGNITION MOTIF-CONTAINING PROTEIN NO-ON-TRANSIENT A nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0038630|UniProtKB=Q9VE58 Q9VE58 Tssk PTHR24343:SF345 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 4 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0014143|UniProtKB=P32027 P32027 croc PTHR11829:SF388 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN CROCODILE RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0030008|UniProtKB=Q9W3J4 Q9W3J4 Dmel\CG2129 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036016|UniProtKB=Q9VT16 Q9VT16 Dmel\CG3306 PTHR46437:SF1 MORN REPEAT-CONTAINING PROTEIN 5 MORN REPEAT-CONTAINING PROTEIN 5 DROME|FlyBase=FBgn0035273|UniProtKB=Q9W083 Q9W083 Dmel\CG12020 PTHR24078:SF553 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 13 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 DROME|FlyBase=FBgn0036282|UniProtKB=Q9VTX2 Q9VTX2 Smyd4-2 PTHR46165:SF5 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 RE32936P protein binding#GO:0005515;histone deacetylase binding#GO:0042826;binding#GO:0005488;enzyme binding#GO:0019899 anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;visual system development#GO:0150063;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;sensory organ development#GO:0007423;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;sensory system development#GO:0048880;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DROME|FlyBase=FBgn0015589|UniProtKB=Q9VAS9 Q9VAS9 Apc PTHR12607:SF13 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY APC-LIKE, ISOFORM A-RELATED protein binding#GO:0005515;beta-catenin binding#GO:0008013;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell fate specification#GO:0001708;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of signal transduction#GO:0009968;nervous system development#GO:0007399;pattern specification process#GO:0007389;regulation of microtubule-based process#GO:0032886;system development#GO:0048731;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cell communication#GO:0010646;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;cell motility#GO:0048870;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;cellular developmental process#GO:0048869;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178 cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;extrinsic component of plasma membrane#GO:0019897;polymeric cytoskeletal fiber#GO:0099513;extrinsic component of membrane#GO:0019898;cell periphery#GO:0071944;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;plasma membrane protein complex#GO:0098797;cytoplasmic microtubule#GO:0005881;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Angiogenesis#P00005>APC#P00195;Wnt signaling pathway#P00057>APC#P01468 DROME|FlyBase=FBgn0039066|UniProtKB=Q9VCP0 Q9VCP0 EloA PTHR15141:SF76 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 DROME|FlyBase=FBgn0036325|UniProtKB=Q9VU26 Q9VU26 anon-WO0140519.236 PTHR22667:SF0 AT01380P-RELATED AT01380P-RELATED DROME|FlyBase=FBgn0052076|UniProtKB=Q8T8L8 Q8T8L8 Alg10 PTHR12989:SF10 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220 DROME|FlyBase=FBgn0031881|UniProtKB=Q9VM51 Q9VM51 MME1 PTHR45624:SF4 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED CONGESTED-LIKE TRACHEA PROTEIN-RELATED quaternary ammonium group transmembrane transporter activity#GO:0015651;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 DROME|FlyBase=FBgn0037396|UniProtKB=Q9VNK6 Q9VNK6 CtsL3 PTHR12411:SF1033 CYSTEINE PROTEASE FAMILY C1-RELATED RE20049P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0045980|UniProtKB=Q9VC32 Q9VC32 niki PTHR43671:SF106 SERINE/THREONINE-PROTEIN KINASE NEK NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0037529|UniProtKB=Q8SXF0 Q8SXF0 mRpS9 PTHR21569:SF47 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9M binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202 DROME|FlyBase=FBgn0038150|UniProtKB=Q9VFV3 Q9VFV3 yellow-e3 PTHR10009:SF7 PROTEIN YELLOW-RELATED GH10609P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0034989|UniProtKB=Q9W196 Q9W196 Dmel\CG3356 PTHR45700:SF2 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3C ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 DROME|FlyBase=FBgn0038309|UniProtKB=Q9VFA9 Q9VFA9 Amt PTHR11730:SF58 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;homeostatic process#GO:0042592;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0028408|UniProtKB=A8DY77 A8DY77 Drep2 PTHR12306:SF22 CELL DEATH ACTIVATOR CIDE DNAATION FACTOR-RELATED PROTEIN 2, ISOFORM B molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;lipid transfer activity#GO:0120013 programmed cell death#GO:0012501;cellular component organization#GO:0016043;organelle organization#GO:0006996;apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219;lipid storage#GO:0019915;organelle fusion#GO:0048284;lipid droplet organization#GO:0034389;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0030897|UniProtKB=P37236 P37236 Frq1 PTHR23055:SF198 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 1 metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851 calmodulin-related#PC00061 DROME|FlyBase=FBgn0051473|UniProtKB=Q8INR5 Q8INR5 Dmel\CG31473 PTHR10851:SF0 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXINE-5'-PHOSPHATE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule biosynthetic process#GO:0044283;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidase#PC00175;oxidoreductase#PC00176 Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061 DROME|FlyBase=FBgn0032813|UniProtKB=Q9VIT0 Q9VIT0 PCNA2 PTHR11352:SF0 PROLIFERATING CELL NUCLEAR ANTIGEN DNA SLIDING CLAMP PCNA enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 mismatch repair#GO:0006298;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;DNA-templated DNA replication#GO:0006261;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA polymerase processivity factor#PC00015 DNA replication#P00017>PCNA#P00534 DROME|FlyBase=FBgn0000552|UniProtKB=P27780 P27780 Edg84A PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0051301|UniProtKB=Q9VF83 Q9VF83 CG12258 PTHR16148:SF24 NF-KAPPA-B-REPRESSING FACTOR-RELATED LD33178P nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0039041|UniProtKB=Q9VCS1 Q9VCS1 Dmel\CG13838 PTHR34344:SF1 UPF0184 PROTEIN C9ORF16 BUBLIN COILED-COIL PROTEIN cellular component assembly#GO:0022607;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;intermediate filament bundle assembly#GO:0045110;intermediate filament organization#GO:0045109 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 DROME|FlyBase=FBgn0033659|UniProtKB=Q7KHI6 Q7KHI6 Damm PTHR10454:SF251 CASPASE AT03047P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;programmed cell death#GO:0012501;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protease#PC00190 FAS signaling pathway#P00020>Pro-Caspase6#P00607;FAS signaling pathway#P00020>Caspase6#P00596 DROME|FlyBase=FBgn0033247|UniProtKB=Q7K2X8 Q7K2X8 Nup44A PTHR11024:SF3 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER NUCLEOPORIN SEH1 positive regulation of response to stimulus#GO:0048584;cellular response to amino acid starvation#GO:0034198;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to stress#GO:0006950;positive regulation of TORC1 signaling#GO:1904263;response to nutrient levels#GO:0031667;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TORC1 signaling#GO:1903432;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;nuclear protein-containing complex#GO:0140513;Seh1-associated complex#GO:0035859;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0030964|UniProtKB=Q9VWP6 Q9VWP6 Pvf1 PTHR11633:SF1 PLATELET-DERIVED GROWTH FACTOR LD28763P growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of cell migration#GO:0030335;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;regulation of cell migration#GO:0030334 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 DROME|FlyBase=FBgn0266518|UniProtKB=A1Z6M6 A1Z6M6 Dpit47 PTHR46035:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 4 HSP70_HSP90 CO-CHAPERONE CNS1 HOMOLOG protein-folding chaperone binding#GO:0051087;binding#GO:0005488;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;protein binding#GO:0005515;Hsp70 protein binding#GO:0030544 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0037633|UniProtKB=Q9VHL1 Q9VHL1 Dmel\CG9839 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 DROME|FlyBase=FBgn0024991|UniProtKB=Q8IRV6 Q8IRV6 EG:95B7.10 PTHR23099:SF0 TRANSCRIPTIONAL REGULATOR GERM CELL NUCLEAR ACIDIC PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024 DROME|FlyBase=FBgn0032414|UniProtKB=Q9VKA7 Q9VKA7 Dmel\CG17211 PTHR46698:SF3 CROSSVEINLESS 2 VWFC DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0262124|UniProtKB=A0A0B7P9G0 A0A0B7P9G0 uex PTHR12064:SF94 METAL TRANSPORTER CNNM UNEXTENDED PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0031505|UniProtKB=Q9VQM2 Q9VQM2 ND-B14.5B PTHR13099:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B14.5B NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C2-RELATED respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0040601|UniProtKB=A0A0B4KHG9 A0A0B4KHG9 Dmel\CG13643 PTHR22933:SF47 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0026390|UniProtKB=P81916 P81916 Or33c PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034972|UniProtKB=Q9W1B3 Q9W1B3 Dmel\CG10339 PTHR43903:SF12 NEUROLIGIN CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN apical junction complex#GO:0043296;cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;tight junction#GO:0070160;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0284436|UniProtKB=Q7K3J0 Q7K3J0 CCT8 PTHR11353:SF19 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA ISOFORM X1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperonin#PC00073 DROME|FlyBase=FBgn0036588|UniProtKB=Q9VV10 Q9VV10 Dmel\CG13068 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0032586|UniProtKB=Q9V3W1 Q9V3W1 Tpr2 PTHR44200:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 chaperone#PC00072 DROME|FlyBase=FBgn0032204|UniProtKB=Q95TN1 Q95TN1 CG4953 PTHR13134:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0024555|UniProtKB=Q9VFS5 Q9VFS5 flfl PTHR23318:SF27 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 cellular response to stress#GO:0033554;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002 DROME|FlyBase=FBgn0024238|UniProtKB=Q8IQZ7 Q8IQZ7 Fim PTHR19961:SF81 FIMBRIN/PLASTIN FI19014P1 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament bundle assembly#GO:0051017;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0028997|UniProtKB=Q9VH94 Q9VH94 nmdyn-D7 PTHR43109:SF2 NUCLEOSIDE DIPHOSPHATE KINASE 7 NUCLEOSIDE DIPHOSPHATE KINASE 7 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;cytoplasmic microtubule#GO:0005881 kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907 DROME|FlyBase=FBgn0036987|UniProtKB=Q9VPF9 Q9VPF9 IntS15 PTHR14540:SF2 INTEGRATOR COMPLEX SUBUNIT 15 INTEGRATOR COMPLEX SUBUNIT 15 intracellular organelle#GO:0043229;integrator complex#GO:0032039;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0033905|UniProtKB=A1Z9M0 A1Z9M0 Dmel\CG18324 PTHR45928:SF1 RE38146P RE38146P DROME|FlyBase=FBgn0004872|UniProtKB=Q9VKM1 Q9VKM1 piwi PTHR22891:SF189 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN AUBERGINE-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;male gamete generation#GO:0048232;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 DROME|FlyBase=FBgn0038130|UniProtKB=Q9VFX5 Q9VFX5 Dmel\CG8630 PTHR11351:SF21 ACYL-COA DESATURASE GH07782P-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid biosynthetic process#GO:0072330;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;unsaturated fatty acid biosynthetic process#GO:0006636;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 DROME|FlyBase=FBgn0033401|UniProtKB=Q9V564 Q9V564 Cog6 PTHR21506:SF0 COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6 cellular component organization#GO:0016043;organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;Golgi organization#GO:0007030;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 COG complex#GO:0017119;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0004914|UniProtKB=P49866 P49866 Hnf4 PTHR24083:SF104 NUCLEAR HORMONE RECEPTOR TRANSCRIPTION FACTOR HNF-4 HOMOLOG transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0032725|UniProtKB=Q9VJ33 Q9VJ33 Nedd8 PTHR10666:SF173 UBIQUITIN UBIQUITIN-LIKE PROTEIN NEDD8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;nucleus#GO:0005634;ribosome#GO:0005840 DROME|FlyBase=FBgn0259243|UniProtKB=P16905 P16905 Pka-R1 PTHR11635:SF152 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Cell cycle#P00013>Protein kinase subunit#P00482;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Endothelin signaling pathway#P00019>PKA#P00570;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035 DROME|FlyBase=FBgn0030543|UniProtKB=Q9VY58 Q9VY58 Dmel\CG11585 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0038570|UniProtKB=Q960M4 Q960M4 Prx5 PTHR10430:SF41 PEROXIREDOXIN PEROXIREDOXIN-5, MITOCHONDRIAL antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular process#GO:0009987;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;mitochondrion#GO:0005739;microbody#GO:0042579 oxidoreductase#PC00176 DROME|FlyBase=FBgn0038088|UniProtKB=Q86PF4 Q86PF4 Dmel\CG10126 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0037028|UniProtKB=Q9VPA9 Q9VPA9 GYCb100B PTHR21419:SF29 FAMILY NOT NAMED LD24894P DROME|FlyBase=FBgn0260935|UniProtKB=Q9VHH2 Q9VHH2 Vps15 PTHR17583:SF0 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 late endosome to vacuole transport#GO:0045324;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;establishment of protein localization to vacuole#GO:0072666;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;localization#GO:0051179;protein localization to vacuole#GO:0072665;macroautophagy#GO:0016236;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;pexophagy#GO:0000425;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;metabolic process#GO:0008152 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;phosphatidylinositol 3-kinase complex, class III#GO:0035032;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle membrane contact site#GO:0044232;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;membrane#GO:0016020 kinase modulator#PC00140;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0013276|UniProtKB=P02825 P02825 Hsp70Ab PTHR19375:SF518 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN AA-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515 metabolic process#GO:0008152;protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Hsp70 family chaperone#PC00027;chaperone#PC00072 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 DROME|FlyBase=FBgn0036746|UniProtKB=M9PFU2 M9PFU2 Crtc PTHR13589:SF15 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR, ISOFORM B binding#GO:0005488;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;positive regulation of DNA-templated transcription#GO:0045893 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0036820|UniProtKB=Q9VVT6 Q9VVT6 Grx1 PTHR45694:SF30 GLUTAREDOXIN 2 GLUTAREDOXIN-2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176 DROME|FlyBase=FBgn0028932|UniProtKB=Q9V3M2 Q9V3M2 Dmel\CG16890 PTHR11567:SF25 ACID PHOSPHATASE-RELATED PROTEIN FRA10AC1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 DROME|FlyBase=FBgn0036465|UniProtKB=Q9VUJ4 Q9VUJ4 Rpn12R PTHR12387:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;proteasome regulatory particle, lid subcomplex#GO:0008541 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0039055|UniProtKB=Q9VCQ7 Q9VCQ7 Rassf PTHR22738:SF15 RASSF LD40758P regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0040817|UniProtKB=Q9VTM7 Q9VTM7 DIGF-7 PTHR39957:SF1 AT09846P1-RELATED AT09846P1-RELATED DROME|FlyBase=FBgn0037375|UniProtKB=Q4QPP5 Q4QPP5 kat-60L1 PTHR23074:SF152 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A1 catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0027083|UniProtKB=Q9VFL5 Q9VFL5 MetRS-m PTHR43326:SF8 METHIONYL-TRNA SYNTHETASE METHIONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0031045|UniProtKB=Q9VWF3 Q9VWF3 CG14122 PTHR20889:SF12 PHOSPHATASE, ORPHAN 1, 2 LP01149P catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0033127|UniProtKB=Q7K010 Q7K010 Tsp42Ef PTHR19282:SF519 TETRASPANIN TETRASPANIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0000527|UniProtKB=Q9VDC6 Q9VDC6 e PTHR44845:SF8 CARRIER DOMAIN-CONTAINING PROTEIN BETA-ALANYL-BIOAMINE NONRIBOSOMAL PEPTIDE SYNTHETASE EBONY ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518;amino acid activation#GO:0043038;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0039094|UniProtKB=Q9VCK6 Q9VCK6 Dmel\CG10184 PTHR48097:SF9 L-THREONINE ALDOLASE-RELATED L-THREONINE ALDOLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 aldolase#PC00044;lyase#PC00144 DROME|FlyBase=FBgn0033848|UniProtKB=A1Z9E4 A1Z9E4 Dmel\CG13330 PTHR13585:SF19 CHASCON, ISOFORM D-RELATED CHASCON, ISOFORM D-RELATED DROME|FlyBase=FBgn0263780|UniProtKB=A0A0C4DHM8 A0A0C4DHM8 Dmel\CG17684 PTHR11731:SF187 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10-LIKE PROTEIN catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203;protease#PC00190 DROME|FlyBase=FBgn0039568|UniProtKB=Q9VAX6 Q9VAX6 Dmel\CG4815 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0016970|UniProtKB=Q9V574 Q9V574 l(2)k10201 PTHR21354:SF0 ZINC FINGER PROTEIN 511 ZINC FINGER PROTEIN 511 DROME|FlyBase=FBgn0005564|UniProtKB=P17971 P17971 Shal PTHR11537:SF105 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAL transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241;ion channel#PC00133 DROME|FlyBase=FBgn0028694|UniProtKB=Q9V3H2 Q9V3H2 Rpn11 PTHR10410:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED UBIQUITIN C-TERMINAL HYDROLASE PSMD14 catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;proteasome complex#GO:0000502;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368 translation factor#PC00223;translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 DROME|FlyBase=FBgn0025624|UniProtKB=O77262 O77262 anon-WO0140519.169 PTHR21324:SF21 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED EG:22E5.9 PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035397|UniProtKB=Q95RR8 Q95RR8 PAN3 PTHR12272:SF11 DEADENYLATION COMPLEX SUBUNIT PAN3 PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494 exoribonuclease#PC00099 DROME|FlyBase=FBgn0036096|UniProtKB=Q9VTB0 Q9VTB0 Dmel\CG8003 PTHR24150:SF8 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 DROME|FlyBase=FBgn0040493|UniProtKB=A0A0C4FEI8 A0A0C4FEI8 grsm PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0034716|UniProtKB=Q9W269 Q9W269 Oatp58Dc PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0029882|UniProtKB=Q9W3Y3 Q9W3Y3 Dmel\CG3226 PTHR13164:SF3 CALICYLIN BINDING PROTEIN CALCYCLIN-BINDING PROTEIN ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501 nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030653|UniProtKB=Q9VXT7 Q9VXT7 CG7860 PTHR10188:SF41 L-ASPARAGINASE ISOASPARTYL PEPTIDASE_L-ASPARAGINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0024912|UniProtKB=O76339 O76339 agt PTHR10815:SF13 METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE DNA metabolism protein#PC00009;DNA methyltransferase#PC00013 DROME|FlyBase=FBgn0036043|UniProtKB=Q9VT48 Q9VT48 Ae2 PTHR11453:SF47 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;biological regulation#GO:0065007;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0001105|UniProtKB=P26308 P26308 Gbeta13F PTHR19850:SF25 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;signaling adaptor activity#GO:0035591 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562 protein-binding activity modulator#PC00095;heterotrimeric G-protein#PC00117;G-protein#PC00020 Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;PI3 kinase pathway#P00048>Gbetagamma#P01188;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458 DROME|FlyBase=FBgn0052772|UniProtKB=Q9W4F9 Q9W4F9 CG6911 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0033377|UniProtKB=A1Z7P1 A1Z7P1 Pgm2a PTHR45745:SF1 PHOSPHOMANNOMUTASE 45A PHOSPHOGLUCOMUTASE 2A-RELATED isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside metabolic process#GO:0042278;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine-containing compound biosynthetic process#GO:0072522 mutase#PC00160;metabolite interconversion enzyme#PC00262;isomerase#PC00135 DROME|FlyBase=FBgn0016122|UniProtKB=Q9VLJ6 Q9VLJ6 Acer PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038198|UniProtKB=Q9VFN7 Q9VFN7 Npc2b PTHR11306:SF71 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED GEO07678P1 steroid binding#GO:0005496;lipid binding#GO:0008289;sterol binding#GO:0032934;binding#GO:0005488 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;sterol transport#GO:0015918;localization#GO:0051179;organic hydroxy compound transport#GO:0015850 DROME|FlyBase=FBgn0261986|UniProtKB=Q9VBP2 Q9VBP2 RASSF8 PTHR15286:SF6 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN GH01133P scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0250903|UniProtKB=Q7KA43 Q7KA43 lmgA PTHR11210:SF1 RING BOX ANAPHASE-PROMOTING COMPLEX SUBUNIT 11 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 regulation of organelle organization#GO:0033043;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;regulation of chromosome separation#GO:1905818;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of chromosome organization#GO:0033044;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0037778|UniProtKB=Q9VH38 Q9VH38 mtTFB2 PTHR11727:SF13 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 2, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102 rRNA modification#GO:0000154;DNA-templated transcription initiation#GO:0006352;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;methylation#GO:0032259;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;mitochondrial gene expression#GO:0140053;rRNA processing#GO:0006364;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mitochondrial transcription#GO:0006390;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0260771|UniProtKB=Q9W362 Q9W362 Larp7 PTHR22792:SF159 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 7 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035989|UniProtKB=Q9VSY4 Q9VSY4 Atat PTHR12327:SF0 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acyltransferase activity#GO:0140186;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 DROME|FlyBase=FBgn0032005|UniProtKB=M9NDI3 M9NDI3 Snx6 PTHR45850:SF7 SORTING NEXIN FAMILY MEMBER SORTING NEXIN 6, ISOFORM B vesicle fusion#GO:0006906;endocytosis#GO:0006897;cellular component organization#GO:0016043;vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;cellular process#GO:0009987;lysosome organization#GO:0007040;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;vesicle organization#GO:0016050;import into cell#GO:0098657;establishment of localization#GO:0051234;apoptotic cell clearance#GO:0043277;cellular component organization or biogenesis#GO:0071840;lytic vacuole organization#GO:0080171;transport#GO:0006810;phagocytosis#GO:0006909;phagolysosome assembly#GO:0001845 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051445|UniProtKB=Q95SR0 Q95SR0 CG11955 PTHR11533:SF253 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED metallopeptidase activity#GO:0008237;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;primary metabolic process#GO:0044238;peptide catabolic process#GO:0043171;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0286786|UniProtKB=Q9U3Z7 Q9U3Z7 hoip PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0052263|UniProtKB=Q8IRC8 Q8IRC8 CG10854 PTHR11266:SF8 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transporter#PC00227 DROME|FlyBase=FBgn0288631|UniProtKB=Q8IMR4 Q8IMR4 Yif1 PTHR14083:SF0 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN YIP1-INTERACTING FACTOR 1, ISOFORM C establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783 DROME|FlyBase=FBgn0038855|UniProtKB=Q95RC5 Q95RC5 Tbc1d22 PTHR22957:SF26 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN LD44506P molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0038068|UniProtKB=Q9VG48 Q9VG48 Dmel\CG11600 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 hydrolase#PC00121;lipase#PC00143 DROME|FlyBase=FBgn0019990|UniProtKB=A0A0B4KHX7 A0A0B4KHX7 Gcn2 PTHR11042:SF202 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EIF-2-ALPHA KINASE GCN2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular response to amino acid starvation#GO:0034198;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stress#GO:0033554;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0030611|UniProtKB=Q9VXY4 Q9VXY4 CG15027 PTHR13349:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0037710|UniProtKB=Q9VHB6 Q9VHB6 CG9393 PTHR12289:SF41 METAXIN RELATED METAXIN-1 HOMOLOG establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;protein insertion into membrane#GO:0051205;cellular component assembly#GO:0022607;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transporter#PC00227 DROME|FlyBase=FBgn0004780|UniProtKB=O97061 O97061 Ccp84Ad PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0028375|UniProtKB=Q9V3R8 Q9V3R8 heix PTHR13929:SF17 1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE UBIA PRENYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824 ketone metabolic process#GO:0042180;vitamin K metabolic process#GO:0042373;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;menaquinone biosynthetic process#GO:0009234;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 transferase#PC00220 DROME|FlyBase=FBgn0024285|UniProtKB=Q9VL71 Q9VL71 Srp54 PTHR32343:SF84 SERINE/ARGININE-RICH SPLICING FACTOR LD29830P RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0034279|UniProtKB=A1ZAZ7 A1ZAZ7 Dmel\CG18635 PTHR16024:SF27 XK-RELATED PROTEIN XK-RELATED PROTEIN cell death#GO:0008219;programmed cell death#GO:0012501;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;localization#GO:0051179;anatomical structure development#GO:0048856;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid transport#GO:0006869;developmental process#GO:0032502;transport#GO:0006810;phagocytosis#GO:0006909;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization#GO:0016043;endocytosis#GO:0006897;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane invagination#GO:0010324;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0000405|UniProtKB=P20439 P20439 CycB PTHR10177:SF347 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 kinase activator#PC00138 p53 pathway#P00059>Cyclin B#P04614;Cell cycle#P00013>Cyclin B#P00486 DROME|FlyBase=FBgn0038547|UniProtKB=Q9VEF4 Q9VEF4 Dmel\CG17803 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0266717|UniProtKB=A0A0B4KG50 A0A0B4KG50 Bruce PTHR46116:SF39 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME DUAL E2 UBIQUITIN-CONJUGATING ENZYME_E3 UBIQUITIN-PROTEIN LIGASE BIRC6 catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032236|UniProtKB=Q9VKX4 Q9VKX4 mRpS7 PTHR11205:SF19 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7M mRNA binding#GO:0003729;structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0034231|UniProtKB=Q9V831 Q9V831 APC10 PTHR12936:SF0 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cell cycle#GO:0007049;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Cell cycle#P00013>APC#P00481 DROME|FlyBase=FBgn0035124|UniProtKB=Q9W0S3 Q9W0S3 ttm2 PTHR12210:SF3 DULLARD PROTEIN PHOSPHATASE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50 phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 protein phosphatase#PC00195 DROME|FlyBase=FBgn0038751|UniProtKB=Q9VDS1 Q9VDS1 Dmel\CG4770 PTHR11011:SF130 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579 DROME|FlyBase=FBgn0034985|UniProtKB=A0A0B4LGG8 A0A0B4LGG8 Dmel\CG3328 PTHR13029:SF18 FAMILY NOT NAMED MYELIN REGULATORY FACTOR HOMOLOG 1 sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;proteolysis#GO:0006508;regulation of biological process#GO:0050789;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;positive regulation of cellular process#GO:0048522 organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;nucleus#GO:0005634;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 DROME|FlyBase=FBgn0031720|UniProtKB=Q9VMP6 Q9VMP6 Dmel\CG14013 PTHR33588:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 structural protein#PC00211 DROME|FlyBase=FBgn0028844|UniProtKB=Q9VJS6 Q9VJS6 Dmel\CG15283 PTHR28524:SF3 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL chaperone#PC00072 DROME|FlyBase=FBgn0260794|UniProtKB=Q9VN58 Q9VN58 ctrip PTHR45670:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;DNA damage response#GO:0006974;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0002873|UniProtKB=Q8IR55 Q8IR55 mud PTHR18902:SF32 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED FI04457P-RELATED cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0032076|UniProtKB=Q9VLG9 Q9VLG9 Argl PTHR43814:SF1 ARGININOSUCCINATE LYASE ARGININOSUCCINATE LYASE catalytic activity#GO:0003824;lyase activity#GO:0016829 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 lyase#PC00144 Arginine biosynthesis#P02728>argininosuccinate lyase#P02841 DROME|FlyBase=FBgn0042175|UniProtKB=Q9I7L9 Q9I7L9 Dmel\CG18858 PTHR11440:SF114 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED BCDNA.GH02384 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0037619|UniProtKB=Q9VHM5 Q9VHM5 Dmel\CG8159 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0034933|UniProtKB=Q9W1G1 Q9W1G1 Dmel\CG3735 PTHR12933:SF0 ORF PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;rRNA binding#GO:0019843 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0053179|UniProtKB=Q9VJF7 Q9VJF7 beat-IIIb PTHR21261:SF19 BEAT PROTEIN BEATEN PATH IIIA, ISOFORM D-RELATED anatomical structure morphogenesis#GO:0009653;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0259099|UniProtKB=Q9VUI3 Q9VUI3 DCX-EMAP PTHR13720:SF55 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE CG42247 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0054002|UniProtKB=Q2PDZ4 Q2PDZ4 MIP08535 PTHR10334:SF615 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0036203|UniProtKB=Q9VTN2 Q9VTN2 Muc68D PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0034800|UniProtKB=Q8T8S2 Q8T8S2 Dmel\CG3788 PTHR43691:SF11 URIDINE PHOSPHORYLASE FI09636P-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 DROME|FlyBase=FBgn0034722|UniProtKB=Q9W261 Q9W261 Rtf1 PTHR13115:SF8 RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0010622|UniProtKB=Q9W1V8 Q9W1V8 DCTN3-p24 PTHR28360:SF1 DYNACTIN SUBUNIT 3 DYNACTIN SUBUNIT 3 cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;cell cycle#GO:0007049;cytokinesis#GO:0000910 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0032895|UniProtKB=Q9VII3 Q9VII3 twit PTHR33562:SF30 ATILLA, ISOFORM B-RELATED-RELATED UPAR_LY6 DOMAIN-CONTAINING PROTEIN TWIT DROME|FlyBase=FBgn0038470|UniProtKB=Q9VEP2 Q9VEP2 Dmel\CG18213 PTHR46165:SF6 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 SET AND MYND DOMAIN CONTAINING, CLASS 4, MEMBER 3 protein binding#GO:0005515;histone deacetylase binding#GO:0042826;binding#GO:0005488;enzyme binding#GO:0019899 visual system development#GO:0150063;cell development#GO:0048468;cell differentiation#GO:0030154;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;anatomical structure morphogenesis#GO:0009653;system development#GO:0048731;neuron development#GO:0048666;eye development#GO:0001654;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sensory system development#GO:0048880;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;sensory organ development#GO:0007423 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0030350|UniProtKB=Q7Z2C4 Q7Z2C4 SelG PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K monoatomic ion homeostasis#GO:0050801;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of response to stimulus#GO:0048583;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;calcium ion homeostasis#GO:0055074 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0038007|UniProtKB=Q9VGB3 Q9VGB3 Cyp313a3 PTHR24305:SF224 CYTOCHROME P450 CYTOCHROME P450 313A1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0037817|UniProtKB=Q9VGZ0 Q9VGZ0 Cyp12e1 PTHR24305:SF238 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0000257|UniProtKB=Q9Y1I2 Q9Y1I2 car PTHR11679:SF85 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle tethering complex#GO:0099023;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0037860|UniProtKB=Q9VGT9 Q9VGT9 SdhCL PTHR10978:SF5 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646 catalytic complex#GO:1902494;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 dehydrogenase#PC00092 TCA cycle#P00051>Succinate Dehydrogenase#P01273 DROME|FlyBase=FBgn0030853|UniProtKB=Q9VX36 Q9VX36 ND-24 PTHR10371:SF3 NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 dehydrogenase#PC00092;oxidoreductase#PC00176 Parkinson disease#P00049>Complex I#P01237 DROME|FlyBase=FBgn0261929|UniProtKB=A0A0B4KFU6 A0A0B4KFU6 5-HT2B PTHR24247:SF222 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE (SEROTONIN) RECEPTOR 2B, ISOFORM E transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;response to oxygen-containing compound#GO:1901700;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0020278|UniProtKB=Q9VCX1 Q9VCX1 loco PTHR45945:SF3 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G-PROTEIN SIGNALING LOCO molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0029968|UniProtKB=Q9W3P0 Q9W3P0 Ir7g PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0026089|UniProtKB=Q9W551 Q9W551 EG:63B12.11 PTHR14520:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 63 LARGE RIBOSOMAL SUBUNIT PROTEIN ML63 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0036661|UniProtKB=Q9VVA0 Q9VVA0 CG9705 PTHR12962:SF1 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED COLD SHOCK DOMAIN-CONTAINING PROTEIN CG9705 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of RNA stability#GO:0043487;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA stability#GO:0043488;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0036747|UniProtKB=Q9VVJ9 Q9VVJ9 Dmel\CG6052 PTHR19229:SF278 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0003008|UniProtKB=Q9W1E8 Q9W1E8 or PTHR11753:SF2 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY ADAPTOR PROTEIN COMPLEX AP-3 SMALL CHAIN SIGMA3 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 DROME|FlyBase=FBgn0038279|UniProtKB=Q9VFE2 Q9VFE2 Sdr PTHR31018:SF3 SPORULATION-SPECIFIC PROTEIN-RELATED EPIDERMAL GROWTH FACTOR RECEPTOR-LIKE ISOFORM X1 DROME|FlyBase=FBgn0001084|UniProtKB=O16868 O16868 fuz PTHR13559:SF1 INTRACELLULAR TRAFFIC PROTEIN-RELATED PROTEIN FUZZY HOMOLOG plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 DROME|FlyBase=FBgn0029161|UniProtKB=Q9V3U9 Q9V3U9 slmo PTHR11158:SF17 MSF1/PX19 RELATED PROTEIN SLOWMO lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0036134|UniProtKB=M9PF47 M9PF47 FoxK PTHR45881:SF7 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED DROME|FlyBase=FBgn0029979|UniProtKB=Q9W3M7 Q9W3M7 mahe PTHR47958:SF73 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA helicase#PC00032 DROME|FlyBase=FBgn0290420|UniProtKB=Q9VBH7 Q9VBH7 Trmt61 PTHR12133:SF2 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0053116|UniProtKB=Q9VIU4 Q9VIU4 Dmel\CG33116 PTHR10414:SF71 ETHANOLAMINEPHOSPHOTRANSFERASE FI05338P transferase#PC00220 DROME|FlyBase=FBgn0001124|UniProtKB=A1ZAA5 A1ZAA5 Got1 PTHR11879:SF55 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 DROME|FlyBase=FBgn0039674|UniProtKB=Q9VAJ9 Q9VAJ9 Dmel\CG1907 PTHR45618:SF9 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL 2-OXOGLUTARATE_MALATE CARRIER PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0038869|UniProtKB=Q9VDD0 Q9VDD0 Smyd5 PTHR46402:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 5 PROTEIN-LYSINE N-TRIMETHYLTRANSFERASE SMYD5 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 DROME|FlyBase=FBgn0027514|UniProtKB=B9A0M7 B9A0M7 BcDNA:LD21969 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0035044|UniProtKB=Q9W127 Q9W127 Dmel\CG3663 PTHR14119:SF17 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039561|UniProtKB=Q9VAY3 Q9VAY3 mfrn PTHR45758:SF20 MITOFERRIN-1-RELATED MITOFERRIN-2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;iron ion transmembrane transporter activity#GO:0005381 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;iron ion transmembrane transport#GO:0034755;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0033463|UniProtKB=A1Z814 A1Z814 Dmel\CG1513 PTHR10972:SF200 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9 sterol binding#GO:0032934;binding#GO:0005488;steroid binding#GO:0005496;lipid binding#GO:0008289 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytosol#GO:0005829;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0034499|UniProtKB=Q7JZJ3 Q7JZJ3 Cpr56F PTHR12236:SF98 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 56F extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0085486|UniProtKB=Q4V4V0 Q4V4V0 Dmel\CG34457 PTHR24274:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165 structural protein#PC00211 DROME|FlyBase=FBgn0037677|UniProtKB=Q9VHF8 Q9VHF8 SP87 PTHR24276:SF100 POLYSERASE-RELATED FI18310P1-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038515|UniProtKB=Q9VEJ4 Q9VEJ4 Dmel\CG5823 PTHR24068:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Ubc6#P01222 DROME|FlyBase=FBgn0026076|UniProtKB=Q9VXN1 Q9VXN1 UBL3 PTHR13169:SF0 UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN UBIQUITIN-LIKE PROTEIN 3 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0036843|UniProtKB=Q9VVW3 Q9VVW3 Sfxn2 PTHR11153:SF14 SIDEROFLEXIN SIDEROFLEXIN-2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;mitochondrial transmembrane transport#GO:1990542;cellular localization#GO:0051641;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;localization#GO:0051179;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 DROME|FlyBase=FBgn0035154|UniProtKB=Q9W0N8 Q9W0N8 hiro PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 serine protease#PC00203 DROME|FlyBase=FBgn0003380|UniProtKB=P08510 P08510 Sh PTHR11537:SF113 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAKER gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 metal ion transport#GO:0030001;action potential#GO:0001508;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241;ion channel#PC00133 DROME|FlyBase=FBgn0031373|UniProtKB=Q9VQ53 Q9VQ53 mdcds_4396 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0034940|UniProtKB=Q9W1F2 Q9W1F2 Dmel\CG16787 PTHR31094:SF2 RIKEN CDNA 2310061I04 GENE RIKEN CDNA 2310061I04 GENE DROME|FlyBase=FBgn0029676|UniProtKB=Q86DS1 Q86DS1 HIP-R PTHR45883:SF2 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 DROME|FlyBase=FBgn0028530|UniProtKB=Q9V3F3 Q9V3F3 mTTF PTHR15437:SF6 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;binding#GO:0005488 DROME|FlyBase=FBgn0031848|UniProtKB=Q9VMA0 Q9VMA0 Nse1 PTHR20973:SF0 NON-SMC ELEMENT 1-RELATED NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 DROME|FlyBase=FBgn0260970|UniProtKB=Q9W3M3 Q9W3M3 Ubr3 PTHR21497:SF39 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR3 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0039924|UniProtKB=Q8SXX1 Q8SXX1 PIP4K PTHR23086:SF150 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transferase#PC00220;kinase#PC00137 DROME|FlyBase=FBgn0038566|UniProtKB=Q9VED4 Q9VED4 bard PTHR13382:SF87 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B BARD-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 DROME|FlyBase=FBgn0033551|UniProtKB=Q7K2B1 Q7K2B1 Dmel\CG7222 PTHR12378:SF80 DESUMOYLATING ISOPEPTIDASE IP06716P-RELATED ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824 protease#PC00190;cysteine protease#PC00081 DROME|FlyBase=FBgn0004858|UniProtKB=Q9VJS8 Q9VJS8 elB PTHR12522:SF4 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN ELBOW negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0032408|UniProtKB=Q9VKB4 Q9VKB4 CG6712 PTHR22734:SF3 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RIBOSOME PRODUCTION FACTOR 1 RNA binding#GO:0003723;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0011305|UniProtKB=Q24491 Q24491 Rsf1 PTHR23147:SF217 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN RSF1 organelle lumen#GO:0043233;nuclear speck#GO:0016607;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0020307|UniProtKB=Q9W268 Q9W268 dve PTHR15116:SF16 DNA-BINDING PROTEIN SATB FAMILY MEMBER DEFECTIVE PROVENTRICULUS, ISOFORM A RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0011787|UniProtKB=Q9VSR5 Q9VSR5 mRpL12 PTHR45987:SF29 39S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 DROME|FlyBase=FBgn0037175|UniProtKB=Q9VNS9 Q9VNS9 Dmel\CG14455 PTHR20898:SF1 DAEDALUS ON 3-RELATED-RELATED MD-2-RELATED LIPID-RECOGNITION DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0032484|UniProtKB=Q9VK22 Q9VK22 kek4 PTHR24366:SF163 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS KEKKON4 immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0261633|UniProtKB=M9MS11 M9MS11 Dmel\CG42716 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0034497|UniProtKB=Q7JUS9 Q7JUS9 Mpcp1 PTHR45671:SF10 SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 3 secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;phosphate ion transport#GO:0006817 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 mitochondrial carrier protein#PC00158 DROME|FlyBase=FBgn0000330|UniProtKB=O76928 O76928 cm PTHR10529:SF340 AP COMPLEX SUBUNIT MU CARMINE, ISOFORM A cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;vacuolar transport#GO:0007034;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;AP-type membrane coat adaptor complex#GO:0030119 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0034726|UniProtKB=Q9W256 Q9W256 PolE4 PTHR10252:SF79 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DNA POLYMERASE EPSILON SUBUNIT 4 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0030261|UniProtKB=Q9VZ37 Q9VZ37 DIGF-1 PTHR39957:SF1 AT09846P1-RELATED AT09846P1-RELATED DROME|FlyBase=FBgn0036372|UniProtKB=Q9VU84 Q9VU84 Abp1 PTHR10829:SF58 CORTACTIN AND DREBRIN DREBRIN-LIKE PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789 intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;lamellipodium#GO:0030027;glutamatergic synapse#GO:0098978;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;cell leading edge#GO:0031252;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0033691|UniProtKB=Q9V668 Q9V668 SEC61G1 PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;localization within membrane#GO:0051668;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;rough endoplasmic reticulum#GO:0005791;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 primary active transporter#PC00068 DROME|FlyBase=FBgn0261610|UniProtKB=Q9W474 Q9W474 Cep162 PTHR34031:SF2 CENTROSOMAL PROTEIN OF 162 KDA CENTROSOMAL PROTEIN OF 162 KDA cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasmic microtubule#GO:0005881;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0029878|UniProtKB=Q9W3Y7 Q9W3Y7 Pat1 PTHR46575:SF1 AMYLOID PROTEIN-BINDING PROTEIN 2 AMYLOID PROTEIN-BINDING PROTEIN 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul2-RING ubiquitin ligase complex#GO:0031462 DROME|FlyBase=FBgn0037610|UniProtKB=Q9VHN4 Q9VHN4 Dmel\CG8043 PTHR22602:SF0 IRON-SULFUR CLUSTER ASSEMBLY FACTOR CAF17/IBA57, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY FACTOR IBA57, MITOCHONDRIAL intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0032069|UniProtKB=Q9VLH9 Q9VLH9 LManVI PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764 glycosidase#PC00110;hydrolase#PC00121 DROME|FlyBase=FBgn0034121|UniProtKB=A1ZAE9 A1ZAE9 Trehl PTHR23403:SF26 TREHALASE TREHALASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;cellular process#GO:0009987;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152 DROME|FlyBase=FBgn0028540|UniProtKB=X2JAD3 X2JAD3 BG:DS00797.2 PTHR11122:SF13 APOSPORY-ASSOCIATED PROTEIN C-RELATED GLUCOSE-6-PHOSPHATE 1-EPIMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0024921|UniProtKB=Q9VRV8 Q9VRV8 Tnpo PTHR10527:SF3 IMPORTIN BETA TRANSPORTIN-1 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 transporter#PC00227 DROME|FlyBase=FBgn0036220|UniProtKB=B7FNL9 B7FNL9 CG5897-RB PTHR23301:SF115 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0031926|UniProtKB=Q9VLZ6 Q9VLZ6 Dmel\CG6739 PTHR24270:SF62 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED CD320 ANTIGEN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219;apolipoprotein#PC00052 DROME|FlyBase=FBgn0031769|UniProtKB=Q9VMI5 Q9VMI5 Dmel\CG9135 PTHR46207:SF1 PROTEIN RCC2 PROTEIN RCC2 protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488;enzyme binding#GO:0019899 intracellular protein localization#GO:0008104;localization#GO:0051179;regulation of chromosome segregation#GO:0051983;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;macromolecule localization#GO:0033036;protein localization to kinetochore#GO:0034501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033886|UniProtKB=Q7K2G1 Q7K2G1 Rpn13 PTHR12225:SF0 ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;proteasome complex#GO:0000502 DROME|FlyBase=FBgn0032839|UniProtKB=Q9VIQ1 Q9VIQ1 AANATL3 PTHR20905:SF33 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0040871|UniProtKB=Q9VY65 Q9VY65 Mic10a PTHR21304:SF0 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0034776|UniProtKB=A0A0B4LH86 A0A0B4LH86 Dmel\CG13527 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0023091|UniProtKB=B6VQA1 B6VQA1 dimm PTHR19290:SF160 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 15 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0034191|UniProtKB=Q7K1C3 Q7K1C3 Dmel\CG6984 PTHR43602:SF1 FAMILY NOT NAMED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0051988|UniProtKB=Q8T0V8 Q8T0V8 CG17401 PTHR24205:SF16 FOUR AND A HALF LIM DOMAINS PROTEIN GH01042P-RELATED transcription cofactor#PC00217 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 DROME|FlyBase=FBgn0035870|UniProtKB=Q9VSH2 Q9VSH2 Gr66a PTHR21143:SF128 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR FOR BITTER TASTE 66A cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031985|UniProtKB=Q9VLT1 Q9VLT1 mon2 PTHR10663:SF333 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PROTEIN MON2 HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;protein localization to vacuole#GO:0072665;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;cytosolic transport#GO:0016482;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;protein targeting to vacuole#GO:0006623;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0003978|UniProtKB=Q9VIP8 Q9VIP8 vls PTHR46853:SF1 METHYLOSOME PROTEIN 50 METHYLOSOME PROTEIN WDR77 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0038917|UniProtKB=Q9VD63 Q9VD63 Dmel\CG6678 PTHR46849:SF1 RCC1 DOMAIN-CONTAINING PROTEIN 1 RCC1 DOMAIN-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0058470|UniProtKB=Q7PLV6 Q7PLV6 Dmel\CG40470 PTHR11533:SF18 PROTEASE M1 ZINC METALLOPROTEASE FI02158P exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177 primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171;catabolic process#GO:0009056;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0035896|UniProtKB=Q9VSK4 Q9VSK4 Dmel\CG6983 PTHR13287:SF2 ADIPOSE-SECRETED SIGNALING PROTEIN ADIPOSE-SECRETED SIGNALING PROTEIN cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0015037|UniProtKB=Q9V558 Q9V558 Cyp4p1 PTHR24291:SF105 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4P1-RELATED oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0022710|UniProtKB=M9PEP2 M9PEP2 Ac13E PTHR45627:SF8 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 9 catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 DROME|FlyBase=FBgn0263456|UniProtKB=X2JAU8 X2JAU8 nwk PTHR15735:SF25 FCH AND DOUBLE SH3 DOMAINS PROTEIN PROTEIN NERVOUS WRECK phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289 cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;neuromuscular synaptic transmission#GO:0007274;regulation of anatomical structure size#GO:0090066;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;regulation of actin polymerization or depolymerization#GO:0008064;synaptic signaling#GO:0099536;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;cell communication#GO:0007154;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537;regulation of actin filament length#GO:0030832;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of protein-containing complex assembly#GO:0043254;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903 cell junction#GO:0030054;neuromuscular junction#GO:0031594;recycling endosome#GO:0055037;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0029092|UniProtKB=Q7JUY7 Q7JUY7 ced-6 PTHR11232:SF77 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 endocytosis#GO:0006897;membrane organization#GO:0061024;cellular component organization#GO:0016043;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;phagocytosis#GO:0006909;transport#GO:0006810;membrane invagination#GO:0010324 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039299|UniProtKB=Q9VBV1 Q9VBV1 Dmel\CG11854 PTHR11008:SF32 PROTEIN TAKEOUT-LIKE PROTEIN GH08336P-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0264305|UniProtKB=M9PHU7 M9PHU7 CG5741 PTHR13466:SF0 TEX2 PROTEIN-RELATED SMP-LTD DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;binding#GO:0005488 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0261938|UniProtKB=Q9VPW4 Q9VPW4 PolrMT PTHR10102:SF28 DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;sequence-specific DNA binding#GO:0043565;catalytic activity, acting on RNA#GO:0140098;sequence-specific double-stranded DNA binding#GO:1990837 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;mitochondrial transcription#GO:0006390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase complex#GO:0030880;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535 DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0038621|UniProtKB=Q9VE68 Q9VE68 Dmel\CG10864 PTHR11003:SF87 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0028862|UniProtKB=Q9V3J9 Q9V3J9 dao PTHR46165:SF8 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 DOWN AND OUT, ISOFORM A-RELATED histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0041111|UniProtKB=Q9VQI9 Q9VQI9 lilli PTHR10528:SF17 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER LILLI transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;system process#GO:0003008;DNA-templated transcription elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;multicellular organismal process#GO:0032501;gene expression#GO:0010467;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nervous system process#GO:0050877;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0016047|UniProtKB=A1Z8J4 A1Z8J4 nompA PTHR47327:SF9 FI18240P1-RELATED NO MECHANORECEPTOR POTENTIAL A, ISOFORM A anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 DROME|FlyBase=FBgn0033573|UniProtKB=A1Z8E3 A1Z8E3 Obp47a PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0265139|UniProtKB=Q9W594 Q9W594 Gr2a PTHR21143:SF104 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 8A-RELATED cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;cell body#GO:0044297;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037855|UniProtKB=Q9VGU5 Q9VGU5 CG6621 PTHR23184:SF9 TETRATRICOPEPTIDE REPEAT PROTEIN 14 TETRATRICOPEPTIDE REPEAT PROTEIN 14 DROME|FlyBase=FBgn0031320|UniProtKB=Q9VPY7 Q9VPY7 Dmel\CG5126 PTHR11012:SF4 PROTEIN KINASE-LIKE DOMAIN-CONTAINING LD42035P DROME|FlyBase=FBgn0035956|UniProtKB=Q9VST2 Q9VST2 Doc2 PTHR11267:SF204 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR 3B DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell fate specification#GO:0001708 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 DROME|FlyBase=FBgn0034727|UniProtKB=Q9W253 Q9W253 mRpS29 PTHR12810:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN MS29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0025558|UniProtKB=O77286 O77286 anon-73B1 PTHR14409:SF0 MANNOSIDASE, BETA A, LYSOSOMAL-LIKE, MANBAL PROTEIN PROTEIN MANBAL DROME|FlyBase=FBgn0036015|UniProtKB=Q9VT15 Q9VT15 Dmel\CG3088 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0050187|UniProtKB=A0A0B4K875 A0A0B4K875 Dmel\CG30187 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0037879|UniProtKB=Q8T3W8 Q8T3W8 scpr-C PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0050361|UniProtKB=A0A0B4KF15 A0A0B4KF15 mtt PTHR24060:SF179 METABOTROPIC GLUTAMATE RECEPTOR MANGETOUT, ISOFORM G adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0052026|UniProtKB=Q8T0R3 Q8T0R3 Dmel\CG32026 PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;alcohol metabolic process#GO:0006066;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 dehydrogenase#PC00092;oxidoreductase#PC00176 Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001 DROME|FlyBase=FBgn0015240|UniProtKB=Q24143 Q24143 Hr96 PTHR24082:SF283 NUCLEAR HORMONE RECEPTOR NUCLEAR HORMONE RECEPTOR HR96 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0032626|UniProtKB=Q4V424 Q4V424 Dmel\CG12620 PTHR12398:SF20 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2 enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 phosphatase inhibitor#PC00183 DROME|FlyBase=FBgn0086450|UniProtKB=Q9W374 Q9W374 su(r) PTHR43073:SF5 DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488 pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Dihydrouracil Dehydrogenase#P03128 DROME|FlyBase=FBgn0038809|UniProtKB=Q9VDK9 Q9VDK9 Dmel\CG16953 PTHR23246:SF13 NEW-GLUE PROTEIN GH12359P DROME|FlyBase=FBgn0037015|UniProtKB=A8JNW3 A8JNW3 cmpy PTHR14186:SF20 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED IGFBP DOMAIN-CONTAINING PROTEIN ISOFORM X1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0000139|UniProtKB=Q94545 Q94545 ash2 PTHR10598:SF0 SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0036184|UniProtKB=Q9VTL1 Q9VTL1 PCID2 PTHR12732:SF0 UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING PCI DOMAIN-CONTAINING PROTEIN 2 DNA binding#GO:0003677;RNA binding#GO:0003723;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;DNA-templated transcription elongation#GO:0006354;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;cellular component organization#GO:0016043;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nucleobase-containing compound transport#GO:0015931;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0033651|UniProtKB=A1Z8P2 A1Z8P2 Ir48c PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0034023|UniProtKB=A1ZA14 A1ZA14 Ir52a PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0263038|UniProtKB=Q8IP52 Q8IP52 Dmel\CG43333 PTHR10900:SF126 PERIOSTIN-RELATED MUCIN-5AC-RELATED binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0032549|UniProtKB=Q9VJR8 Q9VJR8 Dmel\CG4650 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0005612|UniProtKB=P40656 P40656 Sox14 PTHR10270:SF323 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0014023|UniProtKB=Q8T3V6 Q8T3V6 mRpL47 PTHR21183:SF18 RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0004607|UniProtKB=P28167 P28167 zfh2 PTHR45891:SF3 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0032196|UniProtKB=Q9VL21 Q9VL21 Dmel\CG5708 PTHR45787:SF13 LD11652P LD11652P transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0050072|UniProtKB=A1Z9Q4 A1Z9Q4 Obp50c PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0053100|UniProtKB=E1JIV5 E1JIV5 eIF4EHP PTHR11960:SF18 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 DROME|FlyBase=FBgn0265187|UniProtKB=Q7KVJ6 Q7KVJ6 Fatp2 PTHR43107:SF27 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN-FATTY-ACID--COA LIGASE ligase activity, forming carbon-sulfur bonds#GO:0016877;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;monocarboxylic acid transmembrane transporter activity#GO:0008028 establishment of localization#GO:0051234;import into cell#GO:0098657;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0004623|UniProtKB=P29829 P29829 Gbeta76C PTHR19850:SF43 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-2 signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562 G-protein#PC00020;heterotrimeric G-protein#PC00117;protein-binding activity modulator#PC00095 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012 DROME|FlyBase=FBgn0052195|UniProtKB=Q8IQS5 Q8IQS5 Dmel\CG32195 PTHR11012:SF56 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0035903|UniProtKB=Q9VSL1 Q9VSL1 Dmel\CG6765 PTHR23110:SF93 BTB DOMAIN TRANSCRIPTION FACTOR BTB DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0029727|UniProtKB=Q9W4G7 Q9W4G7 Dmel\CG6978 PTHR11662:SF247 SOLUTE CARRIER FAMILY 17 INORGANIC PHOSPHATE COTRANSPORTER-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0030641|UniProtKB=Q9VXV1 Q9VXV1 Dmel\CG6299 PTHR10219:SF25 GLYCOLIPID TRANSFER PROTEIN-RELATED RH52220P phospholipid binding#GO:0005543;transporter activity#GO:0005215;ion binding#GO:0043167;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phospholipid transfer activity#GO:0120014;lipid binding#GO:0008289;lipid transfer activity#GO:0120013 ceramide transport#GO:0035627;membrane organization#GO:0061024;lipid transport#GO:0006869;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;lipid localization#GO:0010876 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0261571|UniProtKB=Q9VJS0 Q9VJS0 Dmel\CG42685 PTHR46730:SF1 POLYCYSTIN-1 POLYCYSTIN-1-LIKE PROTEIN 1 ISOFORM X1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030870|UniProtKB=Q9VX17 Q9VX17 Dmel\CG6398 PTHR21215:SF0 LD36024P LD36024P DROME|FlyBase=FBgn0002638|UniProtKB=P25171 P25171 Rcc1 PTHR45982:SF1 REGULATOR OF CHROMOSOME CONDENSATION HDC11342-RELATED regulation of microtubule-based process#GO:0032886;regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of mitotic spindle assembly#GO:1901673;regulation of organelle assembly#GO:1902115;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0037714|UniProtKB=Q9VHB2 Q9VHB2 Mpc2b PTHR14154:SF154 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 intracellular transport#GO:0046907;carboxylic acid transport#GO:0046942;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monocarboxylic acid transport#GO:0015718;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743 DROME|FlyBase=FBgn0029835|UniProtKB=Q9W443 Q9W443 Dmel\CG5921 PTHR23116:SF40 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED PDZ DOMAIN-CONTAINING PROTEIN cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;stereocilium#GO:0032420;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 DROME|Gene_ORFName=Dmel_CG46508|UniProtKB=A0ACD4DAW0 A0ACD4DAW0 CG46508 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 DROME|FlyBase=FBgn0027498|UniProtKB=Q9Y0Y7 Q9Y0Y7 CG2061 PTHR12736:SF29 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 3 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of cellular response to alcohol#GO:1905957;regulation of biological process#GO:0050789;regulation of response to alcohol#GO:1901419;regulation of abscisic acid-activated signaling pathway#GO:0009787;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 DROME|FlyBase=FBgn0030443|UniProtKB=Q9VYH4 Q9VYH4 Dmel\CG12715 PTHR21461:SF83 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0052379|UniProtKB=Q9VS65 Q9VS65 CG18415 PTHR11705:SF140 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI02848P-RELATED peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0262624|UniProtKB=Q9W068 Q9W068 Tmhs PTHR12489:SF1 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LP10272P cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0019949|UniProtKB=O17432 O17432 Cdk9 PTHR24056:SF233 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 9 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033679|UniProtKB=Q7K3N4 Q7K3N4 Dmel\CG8888 PTHR43313:SF61 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C GH26015P catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0028669|UniProtKB=A1ZBF7 A1ZBF7 Vha100-3 PTHR11629:SF114 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;binding#GO:0005488;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;proton transmembrane transport#GO:1902600;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 ATPase complex#GO:1904949;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proton-transporting two-sector ATPase complex#GO:0016469;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;protein-containing complex#GO:0032991 ATP synthase#PC00002 DROME|FlyBase=FBgn0037856|UniProtKB=Q9VGU4 Q9VGU4 Leash PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0265192|UniProtKB=Q95RQ4 Q95RQ4 Snp PTHR23044:SF84 3'-5' EXONUCLEASE ERI1-RELATED ERI1 EXORIBONUCLEASE 2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular component organization#GO:0051128;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of cellular component organization#GO:0051129;positive regulation of biosynthetic process#GO:0009891;rRNA processing#GO:0006364;regulation of chromatin organization#GO:1902275 exoribonuclease#PC00099 DROME|FlyBase=FBgn0052579|UniProtKB=M9PHA4 M9PHA4 Xkr PTHR16024:SF28 XK-RELATED PROTEIN XK-RELATED PROTEIN cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane invagination#GO:0010324;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;cellular component organization#GO:0016043;endocytosis#GO:0006897;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;macromolecule localization#GO:0033036;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;transport#GO:0006810;developmental process#GO:0032502;phagocytosis#GO:0006909;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cell death#GO:0008219;programmed cell death#GO:0012501;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;anatomical structure development#GO:0048856;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0038135|UniProtKB=Q9VFX0 Q9VFX0 Dmel\CG8773 PTHR11533:SF306 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;peptide catabolic process#GO:0043171;protein processing#GO:0016485;peptide hormone processing#GO:0016486;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;peptide metabolic process#GO:0006518;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;proteolysis#GO:0006508;circulatory system process#GO:0003013;catabolic process#GO:0009056;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0033817|UniProtKB=Q7JYX0 Q7JYX0 GstE14 PTHR43969:SF5 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S-TRANSFERASE E14 glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 DROME|FlyBase=FBgn0030691|UniProtKB=Q9VXP5 Q9VXP5 Efhc1.1 PTHR12086:SF11 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2 anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;regulation of cellular component organization#GO:0051128;regulation of dendrite development#GO:0050773;cell junction organization#GO:0034330;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cell junction assembly#GO:0034329;regulation of dendrite morphogenesis#GO:0048814;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental growth#GO:0048589;regulation of anatomical structure morphogenesis#GO:0022603;neuromuscular junction development#GO:0007528;regulation of cell projection organization#GO:0031344;developmental process#GO:0032502;growth#GO:0040007;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule#GO:0005874;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0010280|UniProtKB=P47825 P47825 Taf4 PTHR15138:SF14 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;Huntington disease#P00029>TAFII130#P00806;General transcription regulation#P00023>TBP-associated factors#P00658 DROME|FlyBase=FBgn0034592|UniProtKB=Q9W2L0 Q9W2L0 CBP5 PTHR46763:SF2 DYNEIN REGULATORY COMPLEX PROTEIN 8 DYNEIN REGULATORY COMPLEX PROTEIN 8 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0004828|UniProtKB=C0HL67 C0HL67 His3.3B PTHR11426:SF287 HISTONE H3 HISTONE H3.3A-RELATED membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 DROME|FlyBase=FBgn0031752|UniProtKB=M9PCP3 M9PCP3 mdcds_8484 PTHR15454:SF75 NISCHARIN RELATED SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037045|UniProtKB=Q9VP86 Q9VP86 anon-WO0118547.713 PTHR23108:SF0 METHYLTRANSFERASE-RELATED METHYLTRANSFERASE-LIKE PROTEIN 22 catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 DROME|FlyBase=FBgn0260027|UniProtKB=A2VER2 A2VER2 Dmel\CG42495 PTHR31965:SF1 TRANSMEMBRANE PROTEIN 42 TRANSMEMBRANE PROTEIN 42 DROME|FlyBase=FBgn0000247|UniProtKB=Q9VAG5 Q9VAG5 ca PTHR22870:SF388 REGULATOR OF CHROMOSOME CONDENSATION CLARET, ISOFORM A guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0041246|UniProtKB=Q9VKJ7 Q9VKJ7 Gr32a PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED cell body#GO:0044297;neuron projection#GO:0043005;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0033019|UniProtKB=A1Z6E8 A1Z6E8 mdcds_12730 PTHR21561:SF12 INO80 COMPLEX SUBUNIT B INO80 COMPLEX SUBUNIT B membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 DROME|FlyBase=FBgn0004198|UniProtKB=P10180 P10180 ct PTHR14043:SF18 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0015379|UniProtKB=P54353 P54353 dod PTHR10657:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED catalytic activity#GO:0003824;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072 DROME|FlyBase=FBgn0026756|UniProtKB=Q9VIM9 Q9VIM9 Ugt37A1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 DROME|FlyBase=FBgn0259978|UniProtKB=Q7K1T1 Q7K1T1 vlc PTHR12353:SF31 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN LD44824P regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794 postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;postsynaptic specialization#GO:0099572;cell junction#GO:0030054;organelle#GO:0043226 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032230|UniProtKB=Q9VKY1 Q9VKY1 lft PTHR31139:SF6 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG PROTEIN LIMB EXPRESSION 1 HOMOLOG cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0031319|UniProtKB=A0A023GRW3 A0A023GRW3 Dmel\CG4896 PTHR13948:SF3 RNA-BINDING PROTEIN FI21118P1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0010385|UniProtKB=P36192 P36192 Def PTHR13645:SF0 DEFENSIN DEFENSIN response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to bacterium#GO:0009617;humoral immune response#GO:0006959;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 DROME|FlyBase=FBgn0038643|UniProtKB=Q59DW1 Q59DW1 Dmel\CG14300 PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0050293|UniProtKB=Q8MLW8 Q8MLW8 Cht12 PTHR11177:SF409 CHITINASE CHITINASE 12-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034906|UniProtKB=Q9W1J6 Q9W1J6 Dmel\CG13561 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0259896|UniProtKB=M9PBB4 M9PBB4 NimC1 PTHR24047:SF29 FI01909P-RELATED EATER-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0030993|UniProtKB=Q9VWL0 Q9VWL0 Mec2 PTHR10264:SF133 BAND 7 PROTEIN-RELATED AT06885P-RELATED channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0027580|UniProtKB=Q0E9E2 Q0E9E2 Pcb PTHR43778:SF4 PYRUVATE CARBOXYLASE PYRUVATE CARBOXYLASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 glucose metabolic process#GO:0006006;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;ligase#PC00142 Pyruvate metabolism#P02772>Pyruvate Carboxylase#P03140 DROME|FlyBase=FBgn0040098|UniProtKB=Q9VLM0 Q9VLM0 lectin-29Ca PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0243512|UniProtKB=Q9VHV8 Q9VHV8 puc PTHR10159:SF528 DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 DROME|FlyBase=FBgn0028931|UniProtKB=Q0E8Q6 Q0E8Q6 DS00797.6 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0039145|UniProtKB=Q9VCD9 Q9VCD9 BcDNA:RE30346 PTHR44086:SF15 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220 DROME|FlyBase=FBgn0013307|UniProtKB=P40807 P40807 Odc1 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 DROME|FlyBase=FBgn0002566|UniProtKB=Q7PL76 Q7PL76 lt PTHR12616:SF1 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 metabolic process#GO:0008152;cellular response to starvation#GO:0009267;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;cellular response to nutrient levels#GO:0031669;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;membrane fusion#GO:0061025;response to stress#GO:0006950;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;cellular response to stress#GO:0033554;localization#GO:0051179;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;response to starvation#GO:0042594;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;vesicle fusion#GO:0006906 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737;vacuolar membrane#GO:0005774;vesicle tethering complex#GO:0099023;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0041174|UniProtKB=Q9V3C1 Q9V3C1 Vhl PTHR15160:SF17 VON HIPPEL-LINDAU PROTEIN VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR enzyme-substrate adaptor activity#GO:0140767;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>VHL#P00816 DROME|FlyBase=FBgn0042712|UniProtKB=Q9W074 Q9W074 HBS1 PTHR23115:SF188 TRANSLATION FACTOR HBS1-LIKE PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rescue of stalled cytosolic ribosome#GO:0072344;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307 translation factor#PC00223 DROME|FlyBase=FBgn0260224|UniProtKB=E1JIY8 E1JIY8 Tcs6 PTHR31283:SF5 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER L ANTIGEN FAMILY MEMBER 3 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0037071|UniProtKB=Q9VP50 Q9VP50 Dmel\CG7632 PTHR43329:SF4 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121 DROME|FlyBase=FBgn0050100|UniProtKB=A1ZAD7 A1ZAD7 Dmel\CG30100 PTHR46203:SF1 PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65 MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translation release factor#PC00225 DROME|FlyBase=FBgn0015288|UniProtKB=P50887 P50887 RpL22 PTHR10064:SF0 60S RIBOSOMAL PROTEIN L22 LARGE RIBOSOMAL SUBUNIT PROTEIN EL22 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribosomal protein#PC00202 DROME|FlyBase=FBgn0004841|UniProtKB=P30974 P30974 TkR86C PTHR24238:SF66 G-PROTEIN COUPLED RECEPTOR TACHYKININ-LIKE PEPTIDES RECEPTOR 86C G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0002939|UniProtKB=Q8INY3 Q8INY3 ninaD PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI02050P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0052685|UniProtKB=M9NGY4 M9NGY4 ZAP3 PTHR13413:SF0 YLP MOTIF CONTAINING PROTEIN NUCLEAR PROTEIN ZAP YLP MOTIF-CONTAINING PROTEIN 1 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of chromosome organization#GO:0033044;regulation of telomere maintenance#GO:0032204 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0030873|UniProtKB=Q9VX13 Q9VX13 Dmel\CG15814 PTHR13407:SF0 RNF121 PROTEIN FI05221P ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221 cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033755|UniProtKB=Q7JZ25 Q7JZ25 ClC-b PTHR11689:SF169 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 7 active transmembrane transporter activity#GO:0022804;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic anion channel activity#GO:0005253 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765 ion channel#PC00133 DROME|FlyBase=FBgn0036742|UniProtKB=Q9VVJ1 Q9VVJ1 Pgr PTHR11866:SF16 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of biological quality#GO:0065008;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0015571|UniProtKB=Q8SZW5 Q8SZW5 alpha-Est3 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0029964|UniProtKB=Q9W3P5 Q9W3P5 D.M.BLPp PTHR12388:SF0 MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle lumen#GO:0043233;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974 transporter#PC00227 DROME|FlyBase=FBgn0033060|UniProtKB=Q29QN4 Q29QN4 Dmel\CG7849 PTHR13195:SF0 PSEUDOURIDINE SYNTHASE-RELATED PSEUDOURIDYLATE SYNTHASE TRUB2, MITOCHONDRIAL intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of biosynthetic process#GO:0009891;macromolecule modification#GO:0043412;positive regulation of translation#GO:0045727;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;mRNA modification#GO:0016556;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;RNA modification#GO:0009451;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lyase#PC00144 DROME|FlyBase=FBgn0036474|UniProtKB=Q9VUK5 Q9VUK5 Or71a PTHR21137:SF37 ODORANT RECEPTOR ODORANT RECEPTOR 46A, ISOFORM B-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0029866|UniProtKB=Q9W404 Q9W404 Dmel\CG3842 PTHR24320:SF289 RETINOL DEHYDROGENASE GH10714P-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0038946|UniProtKB=Q9VD30 Q9VD30 rdhB PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0035372|UniProtKB=Q9VZX8 Q9VZX8 Dmel\CG12093 PTHR34179:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0005674|UniProtKB=P28668 P28668 GluProRS PTHR43382:SF2 PROLYL-TRNA SYNTHETASE BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 DROME|FlyBase=FBgn0286506|UniProtKB=Q9VH77 Q9VH77 Mpi PTHR10309:SF0 MANNOSE-6-PHOSPHATE ISOMERASE MANNOSE-6-PHOSPHATE ISOMERASE catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Mannose metabolism#P02752>Mannose 6-P isomerase#P03017 DROME|FlyBase=FBgn0261933|UniProtKB=Q9VU02 Q9VU02 SmD1 PTHR23338:SF18 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;cytoplasm#GO:0005737;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0038919|UniProtKB=Q9VD61 Q9VD61 Qsox2 PTHR22897:SF8 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein folding#GO:0006457;extracellular structure organization#GO:0043062;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;extracellular matrix assembly#GO:0085029;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034063|UniProtKB=Q0E960 Q0E960 Dmel\CG8389 PTHR11360:SF229 MONOCARBOXYLATE TRANSPORTER SUBFAMILY NOT NAMED transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0039195|UniProtKB=Q9VC80 Q9VC80 Dmel\CG17782 PTHR21398:SF1 AGAP007094-PA FI03705P DROME|FlyBase=FBgn0038892|UniProtKB=Q8T3R9 Q8T3R9 Dmel\CG15498 PTHR24274:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 structural protein#PC00211 DROME|FlyBase=FBgn0050342|UniProtKB=Q7JVL3 Q7JVL3 Prp38 PTHR23142:SF1 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38A nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0024833|UniProtKB=O62531 O62531 AP-1mu PTHR10529:SF262 AP COMPLEX SUBUNIT MU ADAPTOR PROTEIN COMPLEX 1, MU SUBUNIT molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892 transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;vesicle coat#GO:0030120;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin vesicle coat#GO:0030125;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;coated membrane#GO:0048475;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0031604|UniProtKB=Q9VQZ6 Q9VQZ6 Elp3 PTHR11135:SF0 HISTONE ACETYLTRANSFERASE-RELATED ELONGATOR COMPLEX PROTEIN 3 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;elongator holoenzyme complex#GO:0033588;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0036066|UniProtKB=Q9VT78 Q9VT78 Dmel\CG14160 PTHR23529:SF2 GH19118P-RELATED GH19118P-RELATED DROME|FlyBase=FBgn0030412|UniProtKB=Q9VYK6 Q9VYK6 Tomosyn PTHR10241:SF25 LETHAL 2 GIANT LARVAE PROTEIN TOMOSYN, ISOFORM C binding#GO:0005488;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;syntaxin binding#GO:0019905;molecular function activator activity#GO:0140677;myosin binding#GO:0017022;SNARE binding#GO:0000149;enzyme activator activity#GO:0008047;cytoskeletal protein binding#GO:0008092;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization within membrane#GO:0051668;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0034870|UniProtKB=Q9W1P0 Q9W1P0 Dmel\CG13559 PTHR23292:SF6 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16602P1-RELATED ion binding#GO:0043167;zinc ion binding#GO:0008270;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039872|UniProtKB=Q9V9U2 Q9V9U2 salt PTHR42985:SF46 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER FI02923P-RELATED secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transport#GO:0006810;sodium ion transport#GO:0006814 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0263987|UniProtKB=Q7KVW1 Q7KVW1 spoon PTHR22948:SF85 TUDOR DOMAIN CONTAINING PROTEIN RE73736P scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031948|UniProtKB=Q8T0S3 Q8T0S3 dCCS3 PTHR10414:SF36 ETHANOLAMINEPHOSPHOTRANSFERASE GH11618P transferase#PC00220 DROME|FlyBase=FBgn0285925|UniProtKB=P10674 P10674 Fas1 PTHR10900:SF124 PERIOSTIN-RELATED FASCICLIN-1 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;homophilic cell-cell adhesion#GO:0007156;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0034085|UniProtKB=A1ZAB3 A1ZAB3 Ptp52F PTHR19134:SF562 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE FI18312P1 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DROME|FlyBase=FBgn0038915|UniProtKB=Q9VD65 Q9VD65 BcDNA:LP07781 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 plasma membrane bounded cell projection organization#GO:0120036;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;organelle assembly#GO:0070925 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 G-protein#PC00020 DROME|FlyBase=FBgn0038087|UniProtKB=Q9VG24 Q9VG24 beat-Va PTHR21261:SF5 BEAT PROTEIN BEATEN PATH VA, ISOFORM A-RELATED intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0086370|UniProtKB=Q9XZL8 Q9XZL8 sra PTHR10300:SF14 CALCIPRESSIN PROTEIN SARAH enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0005694|UniProtKB=P39413 P39413 Aef1 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0032068|UniProtKB=Q9VLI0 Q9VLI0 LManV PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;glycosidase#PC00110 DROME|FlyBase=FBgn0010590|UniProtKB=A0AQH0 A0AQH0 Prosbeta1 PTHR11599:SF4 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0284421|UniProtKB=O02194 O02194 Psn PTHR10202:SF27 PRESENILIN PRESENILIN HOMOLOG peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;cell communication#GO:0007154;calcium ion homeostasis#GO:0055074;proteolysis#GO:0006508;inorganic ion homeostasis#GO:0098771;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;homeostatic process#GO:0042592;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;monoatomic cation homeostasis#GO:0055080;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;protein maturation#GO:0051604;gene expression#GO:0010467;membrane protein ectodomain proteolysis#GO:0006509;biological regulation#GO:0065007;biosynthetic process#GO:0009058;monoatomic ion homeostasis#GO:0050801;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 protease#PC00190;aspartic protease#PC00053 Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Presenilin#P01110 DROME|FlyBase=FBgn0039086|UniProtKB=Q9VCL4 Q9VCL4 Ugt303B1 PTHR48043:SF145 EG:EG0003.4 PROTEIN-RELATED FI06409P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|Gene_ORFName=Dmel_CG46511|UniProtKB=A0ACD4DAV6 A0ACD4DAV6 CG46511 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;organelle assembly#GO:0070925;gene expression#GO:0010467;cellular component assembly#GO:0022607;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 DROME|FlyBase=FBgn0039673|UniProtKB=A0A0B4KI55 A0A0B4KI55 Dmel\CG7568 PTHR44156:SF33 SUPERNUMERARY LIMBS, ISOFORM B-RELATED DYNEIN ASSEMBLY FACTOR WITH WD REPEAT DOMAINS 1 anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;pattern specification process#GO:0007389;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;determination of left/right symmetry#GO:0007368;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;plasma membrane bounded cell projection assembly#GO:0120031;specification of symmetry#GO:0009799;left/right pattern formation#GO:0060972;developmental process#GO:0032502;regionalization#GO:0003002;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;determination of bilateral symmetry#GO:0009855;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 DROME|FlyBase=FBgn0261385|UniProtKB=Q9V4P1 Q9V4P1 scra PTHR21538:SF23 ANILLIN/RHOTEKIN RTKN ANILLIN mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;septin cytoskeleton organization#GO:0032185;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cortical actin cytoskeleton organization#GO:0030866;septin ring organization#GO:0031106;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell division#GO:0051301;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049 cytoskeleton#GO:0005856;contractile ring#GO:0070938;actomyosin contractile ring#GO:0005826;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0030840|UniProtKB=Q9VX50 Q9VX50 p-cup PTHR21391:SF0 AT04489P-RELATED AT04489P-RELATED DROME|FlyBase=FBgn0033322|UniProtKB=Q7JY68 Q7JY68 BEST:LP01468 PTHR12210:SF70 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 protein phosphatase#PC00195 DROME|FlyBase=FBgn0003444|UniProtKB=P91682 P91682 smo PTHR11309:SF152 FRIZZLED PROTEIN SMOOTHENED binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;pattern specification process#GO:0007389;smoothened signaling pathway#GO:0007224;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;cilium#GO:0005929;dendritic tree#GO:0097447;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Hedgehog signaling pathway#P00025>Smoothened#P00685 DROME|FlyBase=FBgn0039765|UniProtKB=Q9VA81 Q9VA81 mRpS18C PTHR13479:SF40 30S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0020633|UniProtKB=Q9XYU0 Q9XYU0 Mcm7 PTHR11630:SF26 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM7 catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697 DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;MCM complex#GO:0042555;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0031670|UniProtKB=Q9VMV6 Q9VMV6 SelT PTHR13544:SF0 SELENOPROTEIN T THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 DROME|FlyBase=FBgn0016038|UniProtKB=O77259 O77259 Vsp37A PTHR13678:SF25 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 EG:115C2.5 PROTEIN establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;protein metabolic process#GO:0019538;localization#GO:0051179;protein localization to vacuole#GO:0072665;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;protein targeting to vacuole#GO:0006623;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;protein transport#GO:0015031;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;ESCRT I complex#GO:0000813;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0028514|UniProtKB=Q8IP30 Q8IP30 SPH208 PTHR24256:SF462 TRYPTASE-RELATED LP21446P-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0260006|UniProtKB=Q8IR42 Q8IR42 drd PTHR11161:SF4 O-ACYLTRANSFERASE DROP DEAD acyltransferase#PC00042 DROME|FlyBase=FBgn0036775|UniProtKB=Q8SYM9 Q8SYM9 Polr3D PTHR13408:SF0 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0032445|UniProtKB=Q9VK68 Q9VK68 CG6153 PTHR12175:SF7 AD039 HT014 THIOREDOXIN FAMILY TRP26 PITH DOMAIN-CONTAINING PROTEIN 1 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of hemopoiesis#GO:1903706;regulation of myeloid cell differentiation#GO:0045637;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 DROME|FlyBase=FBgn0027588|UniProtKB=Q7KMM4 Q7KMM4 GCS2alpha PTHR22762:SF54 ALPHA-GLUCOSIDASE GLUCOSIDASE II SUBUNIT ALPHA hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599;glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 glucosidase#PC00108 DROME|FlyBase=FBgn0035687|UniProtKB=Q9VRV0 Q9VRV0 Prdm13 PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0037818|UniProtKB=Q9I7K3 Q9I7K3 Dmel\CG6465 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 DROME|FlyBase=FBgn0036911|UniProtKB=Q8WR19 Q8WR19 Fibp PTHR13223:SF3 ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR BINDING PROTEIN AFGF INTRACELLULAR BINDING PROTEIN intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0287768|UniProtKB=P25932 P25932 esg PTHR24388:SF54 ZINC FINGER PROTEIN PROTEIN ESCARGOT DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0025616|UniProtKB=Q9W5D2 Q9W5D2 EG:34F3.9 PTHR47877:SF17 LATE EMBRYOGENESIS ABUNDANT DOMAIN-CONTAINING PROTEIN / LEA DOMAIN-CONTAINING PROTEIN LATE EMBRYOGENESIS ABUNDANT PROTEIN ECP63-LIKE DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0031762|UniProtKB=Q9VMJ4 Q9VMJ4 Dmel\CG9098 PTHR14247:SF8 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3C-RELATED DROME|FlyBase=FBgn0265274|UniProtKB=Q9VAS7 Q9VAS7 Inx3 PTHR11893:SF37 INNEXIN INNEXIN INX3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell communication#GO:0007154 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 gap junction#PC00105 DROME|FlyBase=FBgn0265178|UniProtKB=Q8SX78 Q8SX78 Lipt1 PTHR12561:SF3 LIPOATE-PROTEIN LIGASE LIPOYL AMIDOTRANSFERASE LIPT1, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0085244|UniProtKB=A8DY49 A8DY49 Dmel\CG34215 PTHR39957:SF1 AT09846P1-RELATED AT09846P1-RELATED DROME|FlyBase=FBgn0261554|UniProtKB=Q9W2I0 Q9W2I0 Arms PTHR24116:SF0 KINASE D-INTERACTING SUBSTRATE OF 220 KDA KINASE D-INTERACTING SUBSTRATE OF 220 KDA protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular response to nerve growth factor stimulus#GO:1990090;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 DROME|FlyBase=FBgn0036187|UniProtKB=Q9VTL5 Q9VTL5 RIOK1 PTHR45723:SF5 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0040323|UniProtKB=Q9NHB0 Q9NHB0 GNBP1 PTHR10963:SF70 GLYCOSYL HYDROLASE-RELATED GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glucosidase#PC00108 DROME|FlyBase=FBgn0032314|UniProtKB=Q7KTF1 Q7KTF1 Dmel\CG7309 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED C4-dicarboxylate transmembrane transporter activity#GO:0015556;citrate transmembrane transporter activity#GO:0015137;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;succinate transmembrane transporter activity#GO:0015141 tricarboxylic acid transport#GO:0006842;transport#GO:0006810;carboxylic acid transport#GO:0046942;C4-dicarboxylate transport#GO:0015740;organic acid transport#GO:0015849;citrate transport#GO:0015746;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034459|UniProtKB=A1ZBN5 A1ZBN5 TTLL6A PTHR12241:SF161 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL6 protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631 microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0033872|UniProtKB=Q7K188 Q7K188 Dmel\CG6329 PTHR33562:SF2 ATILLA, ISOFORM B-RELATED-RELATED GEO05126P1 DROME|FlyBase=FBgn0259166|UniProtKB=Q9VY47 Q9VY47 CG1846 PTHR12187:SF11 AGAP000124-PA PHOSPHATIDYLINOSITOL-3,4-BISPHOSPHATE 4-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 DROME|FlyBase=FBgn0024698|UniProtKB=Q9V726 Q9V726 Cpsf160 PTHR10644:SF26 DNA REPAIR/RNA PROCESSING CPSF FAMILY CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0285951|UniProtKB=Q9VV39 Q9VV39 mRpS34 PTHR28589:SF1 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS34 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0035811|UniProtKB=Q9VSA3 Q9VSA3 Mcad PTHR48083:SF41 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 dehydrogenase#PC00092 DROME|FlyBase=FBgn0002069|UniProtKB=Q7K0E6 Q7K0E6 AspRS PTHR43450:SF1 ASPARTYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 cytosol#GO:0005829;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0038490|UniProtKB=Q9VEM1 Q9VEM1 Smug PTHR13235:SF2 SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA glycosylase#PC00010 DROME|FlyBase=FBgn0039129|UniProtKB=Q7KS38 Q7KS38 RpS19b PTHR11710:SF0 40S RIBOSOMAL PROTEIN S19 SMALL RIBOSOMAL SUBUNIT PROTEIN ES19 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 DROME|FlyBase=FBgn0052732|UniProtKB=Q9W3U1 Q9W3U1 Setd3 PTHR13271:SF163 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE ACTIN-HISTIDINE N-METHYLTRANSFERASE protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 methyltransferase#PC00155;transferase#PC00220 DROME|FlyBase=FBgn0000565|UniProtKB=P08761 P08761 MsrA PTHR42799:SF2 MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 reductase#PC00198;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037446|UniProtKB=Q9VI24 Q9VI24 Zif PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0039271|UniProtKB=Q9VBY5 Q9VBY5 Dmel\CG11839 PTHR13278:SF0 ZINC FINGER PROTEIN 830 ZINC FINGER PROTEIN 830 regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic DNA replication checkpoint signaling#GO:0033314;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cellular response to stimulus#GO:0051716;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;biological regulation#GO:0065007;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0262782|UniProtKB=Q9VKX2 Q9VKX2 Mdh1 PTHR23382:SF34 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;oxoacid metabolic process#GO:0043436;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 TCA cycle#P00051>Malate Dehydrogenase#P01270 DROME|FlyBase=FBgn0000667|UniProtKB=P18091 P18091 Actn PTHR11915:SF455 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ, SARCOMERIC-RELATED protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061 membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;I band#GO:0031674;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;Z disc#GO:0030018;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 DROME|FlyBase=FBgn0030871|UniProtKB=Q9VX15 Q9VX15 Rfc37 PTHR11669:SF20 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 4 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 DROME|FlyBase=FBgn0004889|UniProtKB=P36872 P36872 tws PTHR11871:SF0 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B PROTEIN PHOSPHATASE PP2A 55 KDA REGULATORY SUBUNIT phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 DROME|FlyBase=FBgn0036686|UniProtKB=Q9VVC9 Q9VVC9 Dmel\CG7728 PTHR12858:SF2 RIBOSOME BIOGENESIS PROTEIN RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0036316|UniProtKB=Q9VU17 Q9VU17 nebu PTHR48021:SF102 FAMILY NOT NAMED GH07001P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0036414|UniProtKB=M9PI57 M9PI57 nan PTHR10582:SF28 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN NANCHUNG, ISOFORM B passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;calcium ion transmembrane import into cytosol#GO:0097553;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0037550|UniProtKB=Q9VHV6 Q9VHV6 Dmel\CG9667 PTHR13021:SF8 PRE-MRNA-SPLICING FACTOR ISY1 PRE-MRNA-SPLICING FACTOR ISY1 HOMOLOG nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0038773|UniProtKB=Q9VDP7 Q9VDP7 Leo1L PTHR23146:SF0 LEO1 PROTEIN RNA POLYMERASE-ASSOCIATED PROTEIN LEO1 RNA polymerase core enzyme binding#GO:0043175;transcription coregulator activity#GO:0003712;RNA polymerase binding#GO:0070063;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110 DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031183|UniProtKB=Q9VR50 Q9VR50 CG14621 PTHR11132:SF427 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E1 antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0024995|UniProtKB=Q9W4W5 Q9W4W5 Dmel\CG2680 PTHR19288:SF4 4-NITROPHENYLPHOSPHATASE-RELATED RE04130P-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0266569|UniProtKB=Q0KHX4 Q0KHX4 Dmel\CG42259 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0015546|UniProtKB=P43248 P43248 spel1 PTHR11361:SF35 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN SPELLCHECKER 1 DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;response to stimulus#GO:0050896;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0250789|UniProtKB=P13395 P13395 alpha-Spec PTHR11915:SF422 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0031885|UniProtKB=Q9VM47 Q9VM47 Mnn1 PTHR12693:SF3 MENIN MENIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 CCKR signaling map#P06959>MEN1#P07084 DROME|FlyBase=FBgn0031201|UniProtKB=Q9VR70 Q9VR70 Dmel\CG12446 PTHR20992:SF9 AT15442P-RELATED AT15442P-RELATED DROME|FlyBase=FBgn0033392|UniProtKB=A1Z7S7 A1Z7S7 Gnptab PTHR24045:SF0 FAMILY NOT NAMED FI02838P metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0063667|UniProtKB=Q8SXQ8 Q8SXQ8 meep PTHR13204:SF1 PTD012 PROTEIN BETA-KETO L-GULONATE DECARBOXYLASE transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;zinc ion binding#GO:0008270 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0030040|UniProtKB=F0JAP7 F0JAP7 CG15347-RB PTHR21721:SF25 GH09876P-RELATED LP18071P DROME|FlyBase=FBgn0002525|UniProtKB=P08928 P08928 Lam PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;intracellular protein localization#GO:0008104;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;macromolecule localization#GO:0033036;regulation of macromolecule biosynthetic process#GO:0010556;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;chromatin organization#GO:0006325;biological regulation#GO:0065007;organelle localization#GO:0051640;localization within membrane#GO:0051668;localization#GO:0051179;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338 organelle#GO:0043226;endomembrane system#GO:0012505;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229 FAS signaling pathway#P00020>Nuclear Lamin#P00616 DROME|FlyBase=FBgn0051659|UniProtKB=Q8IPX4 Q8IPX4 CG16933 PTHR10612:SF63 APOLIPOPROTEIN D APOLIPOPROTEIN D response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;response to oxygen-containing compound#GO:1901700;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052 DROME|FlyBase=FBgn0034364|UniProtKB=A1ZBA8 A1ZBA8 Dmel\CG5493 PTHR12918:SF1 CYSTEINE DIOXYGENASE CYSTEINE DIOXYGENASE TYPE 1 catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;cation binding#GO:0043169;metal ion binding#GO:0046872;dioxygenase activity#GO:0051213 sulfur compound catabolic process#GO:0044273;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0038492|UniProtKB=A0A0B4KG53 A0A0B4KG53 Mur89F PTHR23301:SF113 CHITIN BINDING PERITROPHIN-A MUCIN RELATED 89F, ISOFORM B binding#GO:0005488;carbohydrate derivative binding#GO:0097367 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035802|UniProtKB=Q7KU89 Q7KU89 Pura PTHR45845:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PURATROPHIN-1-LIKE, ISOFORM A guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0036018|UniProtKB=Q9VT19 Q9VT19 Dmel\CG3335 PTHR23147:SF48 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 19-RELATED membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0011576|UniProtKB=Q27589 Q27589 Cyp4d2 PTHR24291:SF187 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4AE1-RELATED metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0038452|UniProtKB=Q9VES4 Q9VES4 Ccdc114 PTHR21694:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 DROME|FlyBase=FBgn0032821|UniProtKB=Q9VIS1 Q9VIS1 CdGAPr PTHR15729:SF10 CDC42 GTPASE-ACTIVATING PROTEIN GTPASE-ACTIVATING PROTEIN CDGAPR enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0014032|UniProtKB=O76752 O76752 Sptr PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281 reductase#PC00198 DROME|FlyBase=FBgn0038499|UniProtKB=Q9VEL2 Q9VEL2 Brf PTHR11618:SF4 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 DROME|FlyBase=FBgn0034919|UniProtKB=Q9W1H9 Q9W1H9 NdufAF3 PTHR21192:SF2 NUCLEAR PROTEIN E3-3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3 protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0039589|UniProtKB=Q9VAU6 Q9VAU6 Dmel\CG9986 PTHR16525:SF1 PROTEIN C12ORF4 LD27564P cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0052670|UniProtKB=Q8IR98 Q8IR98 Rab9Fb PTHR47980:SF101 LD44762P IP08727P-RELATED export from cell#GO:0140352;endocytic recycling#GO:0032456;secretion by cell#GO:0032940;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;exocytosis#GO:0006887;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;endosome#GO:0005768;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0053526|UniProtKB=Q7KU01 Q7KU01 PNUTS PTHR46557:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10 protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0031251|UniProtKB=Q9VPP2 Q9VPP2 Dmel\CG4213 PTHR23159:SF31 CENTROSOMAL PROTEIN 2 CENTROSOMAL PROTEIN 135KDA, ISOFORM B chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0036687|UniProtKB=Q9VVD0 Q9VVD0 Dmel\CG6652 PTHR16650:SF6 C21ORF13-RELATED GH21622P organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014 DROME|FlyBase=FBgn0030581|UniProtKB=Q8IR46 Q8IR46 Dmel\CG14408 PTHR19423:SF8 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5-LIKE enzyme inhibitor activity#GO:0004857;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;kinase inhibitor activity#GO:0019210;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030425|UniProtKB=Q9VYJ1 Q9VYJ1 Nep6 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0032161|UniProtKB=Q9VL67 Q9VL67 Dmel\CG4594 PTHR11941:SF45 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydratase#PC00120;lyase#PC00144 DROME|FlyBase=FBgn0263108|UniProtKB=Q9VZU5 Q9VZU5 BtbVII PTHR23110:SF81 BTB DOMAIN TRANSCRIPTION FACTOR BTB-PROTEIN-VII, ISOFORM F regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0028871|UniProtKB=Q9V3P9 Q9V3P9 Cpr35B PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0034708|UniProtKB=Q9W277 Q9W277 Vps35 PTHR11099:SF0 VACUOLAR SORTING PROTEIN 35 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;establishment of protein localization to membrane#GO:0090150;endosome to plasma membrane protein transport#GO:0099638;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;endocytic recycling#GO:0032456;cytosolic transport#GO:0016482 membrane#GO:0016020;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;retromer complex#GO:0030904;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0265262|UniProtKB=P48602 P48602 Vha68-1 PTHR43607:SF10 V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A H(+)-TRANSPORTING TWO-SECTOR ATPASE proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;lytic vacuole#GO:0000323;proton-transporting two-sector ATPase complex#GO:0016469;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cation-transporting ATPase complex#GO:0090533;lysosome#GO:0005764;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494 ATP synthase#PC00002 DROME|FlyBase=FBgn0034276|UniProtKB=A1ZAZ2 A1ZAZ2 Sardh PTHR13847:SF200 SARCOSINE DEHYDROGENASE-RELATED SARCOSINE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 dehydrogenase#PC00092 DROME|FlyBase=FBgn0039685|UniProtKB=Q9VAI6 Q9VAI6 Obp99b PTHR11857:SF46 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 99A-RELATED multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0029818|UniProtKB=Q9W464 Q9W464 GAA1 PTHR13304:SF0 GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN GPI-ANCHOR TRANSAMIDASE COMPONENT GPAA1 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchored protein biosynthesis#GO:0180046;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;caspase complex#GO:0008303;peptidase complex#GO:1905368;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;transferase complex#GO:1990234;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0037307|UniProtKB=Q9VN97 Q9VN97 Tim17a2 PTHR10485:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 AT05822P-RELATED transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0038017|UniProtKB=Q9VGA3 Q9VGA3 Dmel\CG4115 PTHR21407:SF3 RE43931P-RELATED LD12305P DROME|FlyBase=FBgn0044871|UniProtKB=Q9VE50 Q9VE50 Gos28 PTHR21094:SF2 GOS-28 SNARE- RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 1 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle fusion#GO:0006906;intra-Golgi vesicle-mediated transport#GO:0006891;cellular component organization#GO:0016043;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi stack#GO:0005795;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150;SNARE protein#PC00034 DROME|FlyBase=FBgn0038865|UniProtKB=Q9VDD5 Q9VDD5 cDIP PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0030334|UniProtKB=Q9VYU5 Q9VYU5 Karl PTHR10612:SF11 APOLIPOPROTEIN D KARL, ISOFORM A response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;lipid metabolic process#GO:0006629;response to oxygen-containing compound#GO:1901700;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 apolipoprotein#PC00052 DROME|FlyBase=FBgn0053554|UniProtKB=Q8I8U7 Q8I8U7 Nipped-A PTHR11139:SF1 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;SAGA complex#GO:0000124;nucleus#GO:0005634;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;SAGA-type complex#GO:0070461;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0083981|UniProtKB=M9PI08 M9PI08 RunxA PTHR11950:SF50 RUNT RELATED RUNT RELATED A, ISOFORM D transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Runt transcription factor#PC00254;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0263219|UniProtKB=M9PHS6 M9PHS6 Dscam4 PTHR10075:SF142 BASIGIN RELATED CELL ADHESION MOLECULE DSCAM2-RELATED multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0039169|UniProtKB=A0A0B4KHC8 A0A0B4KHC8 Spps PTHR23235:SF165 KRUEPPEL-LIKE TRANSCRIPTION FACTOR FI01014P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0031504|UniProtKB=Q4V6K4 Q4V6K4 Dmel\CG15403 PTHR21377:SF0 PROTEIN FAM210B, MITOCHONDRIAL PROTEIN FAM210B, MITOCHONDRIAL intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0016975|UniProtKB=Q24212 Q24212 stnB PTHR10529:SF344 AP COMPLEX SUBUNIT MU PROTEIN STONED-B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of transport#GO:0051049;receptor-mediated endocytosis#GO:0006898;regulation of localization#GO:0032879;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;regulation of endocytosis#GO:0030100;vacuolar transport#GO:0007034;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of cellular component organization#GO:0051128;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;regulation of biological process#GO:0050789;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892 presynapse#GO:0098793;secretory vesicle#GO:0099503;vesicle coat#GO:0030120;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;coated vesicle membrane#GO:0030662;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;synapse#GO:0045202;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;endocytic vesicle#GO:0030139;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;coated membrane#GO:0048475;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cytosol#GO:0005829;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886;transport vesicle#GO:0030133;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;vesicle#GO:0031982;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0036274|UniProtKB=Q9VTW3 Q9VTW3 Dmel\CG4328 PTHR24208:SF175 LIM/HOMEOBOX PROTEIN LHX FI06571P nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0020224|UniProtKB=Q9VSK2 Q9VSK2 Cbl PTHR23007:SF11 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;receptor tyrosine kinase binding#GO:0030971;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of biological process#GO:0048519 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;membrane microdomain#GO:0098857;cell periphery#GO:0071944;membrane raft#GO:0045121;membrane#GO:0016020 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 DROME|FlyBase=FBgn0035538|UniProtKB=Q9VZD1 Q9VZD1 DopEcR PTHR24248:SF172 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE_ECDYSTEROID RECEPTOR, ISOFORM A molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038080|UniProtKB=Q9VG33 Q9VG33 Tst1 PTHR44086:SF15 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 DROME|FlyBase=FBgn0035272|UniProtKB=Q9W086 Q9W086 mRpL46 PTHR13124:SF12 39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN ML46 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 DROME|FlyBase=FBgn0037627|UniProtKB=Q8SZ60 Q8SZ60 c-SPH101 PTHR24260:SF87 AT07769P-RELATED GH08193P-RELATED DROME|FlyBase=FBgn0037974|UniProtKB=Q9VGF2 Q9VGF2 Dmel\CG12224 PTHR42686:SF1 GH17980P-RELATED GH17980P-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0029768|UniProtKB=Q8SWR3 Q8SWR3 SPR PTHR47023:SF1 SEX PEPTIDE RECEPTOR SEX PEPTIDE RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0086908|UniProtKB=Q32KD2 Q32KD2 egg PTHR46024:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0265011|UniProtKB=A1Z7M3 A1Z7M3 Np PTHR24253:SF88 TRANSMEMBRANE PROTEASE SERINE NOTOPLEURAL, ISOFORM A hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039371|UniProtKB=Q9VBM3 Q9VBM3 BcDNA:AT31258 PTHR12300:SF161 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN membrane traffic protein#PC00150 DROME|FlyBase=FBgn0030562|UniProtKB=Q9VY39 Q9VY39 anon-WO0140519.10 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0034645|UniProtKB=Q9W2E8 Q9W2E8 ND-B12 PTHR15082:SF2 NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3 oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176 DROME|FlyBase=FBgn0026395|UniProtKB=P81912 P81912 Or23a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039381|UniProtKB=Q86P97 Q86P97 SppL PTHR12174:SF22 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 3 aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum membrane#GO:0005789;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 aspartic protease#PC00053;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0261086|UniProtKB=A0A0B4KF61 A0A0B4KF61 Syt14 PTHR46129:SF2 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN 14, ISOFORM D lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0019968|UniProtKB=A0A0B4KFR5 A0A0B4KFR5 Khc-73 PTHR24115:SF997 KINESIN-RELATED KINESIN HEAVY CHAIN 73, ISOFORM E cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0025390|UniProtKB=O76894 O76894 Mur2B PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0019637|UniProtKB=Q94546 Q94546 Atu PTHR23146:SF0 LEO1 PROTEIN RNA POLYMERASE-ASSOCIATED PROTEIN LEO1 transcription coregulator activity#GO:0003712;RNA polymerase binding#GO:0070063;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0010516|UniProtKB=Q7KN94 Q7KN94 wal PTHR43153:SF1 ELECTRON TRANSFER FLAVOPROTEIN ALPHA ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363 lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidoreductase#PC00176 DROME|FlyBase=FBgn0039566|UniProtKB=Q9VAX8 Q9VAX8 Dmel\CG4849 PTHR42908:SF6 TRANSLATION ELONGATION FACTOR-RELATED 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT RNA binding#GO:0003723;hydrolase activity#GO:0016787;snRNA binding#GO:0017069;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 nucleobase-containing compound biosynthetic process#GO:0034654;translational elongation#GO:0006414;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;translation#GO:0006412;nucleic acid biosynthetic process#GO:0141187;protein metabolic process#GO:0019538;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein biosynthetic process#GO:0160307;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;small nuclear ribonucleoprotein complex#GO:0030532;cytosol#GO:0005829;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684 translation elongation factor#PC00222 DROME|FlyBase=FBgn0037520|UniProtKB=Q9VHZ8 Q9VHZ8 Dmel\CG18268 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0038261|UniProtKB=Q9VFG1 Q9VFG1 Dmel\CG14856 PTHR24064:SF467 SOLUTE CARRIER FAMILY 22 MEMBER FI01439P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0083966|UniProtKB=Q0KI07 Q0KI07 Dmel\CG34130 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0042102|UniProtKB=Q9I7L0 Q9I7L0 Dmel\CG18745 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0033413|UniProtKB=Q9V579 Q9V579 prel PTHR11158:SF29 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036 mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0030361|UniProtKB=Q9VYR2 Q9VYR2 Dmel\CG1492 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034697|UniProtKB=Q9W289 Q9W289 GM130 PTHR10881:SF46 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 2 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0028982|UniProtKB=Q9W420 Q9W420 Spt6 PTHR10145:SF6 TRANSCRIPTION ELONGATION FACTOR SPT6 TRANSCRIPTION ELONGATION FACTOR SPT6 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0050044|UniProtKB=A8DYB9 A8DYB9 s-cup PTHR31395:SF26 SHISA GEO05642P1-RELATED scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039911|UniProtKB=Q7K4Y8 Q7K4Y8 Dmel\CG1909 PTHR46574:SF1 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 synaptic signaling#GO:0099536;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646 membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synapse#GO:0045202;neuromuscular junction#GO:0031594;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0053519|UniProtKB=A8DYP0 A8DYP0 Obsc PTHR13817:SF163 TITIN PROTEIN OBSCURIN cell development#GO:0048468;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989 structural protein#PC00211 DROME|FlyBase=FBgn0029594|UniProtKB=Q9W549 Q9W549 coa8 PTHR31107:SF2 APOPTOGENIC PROTEIN 1, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 8 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0053768|UniProtKB=Q4ABH8 Q4ABH8 CG14458 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0034284|UniProtKB=A1ZB13 A1ZB13 Dmel\CG14491 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0030710|UniProtKB=Q9VXL5 Q9VXL5 CC9 PTHR23110:SF108 BTB DOMAIN TRANSCRIPTION FACTOR LD19131P regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0050268|UniProtKB=Q9W206 Q9W206 CG13520 PTHR21178:SF8 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 DROME|FlyBase=FBgn0038666|UniProtKB=Q9VE18 Q9VE18 Smu1 PTHR22848:SF0 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0050265|UniProtKB=Q9W1Z3 Q9W1Z3 Dmel\CG30265 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0000562|UniProtKB=Q9W1K4 Q9W1K4 egl PTHR46814:SF1 EGALITARIAN, ISOFORM B EGALITARIAN, ISOFORM B mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 localization#GO:0051179;RNA localization#GO:0006403;macromolecule localization#GO:0033036 DROME|FlyBase=FBgn0027608|UniProtKB=Q9Y164 Q9Y164 BcDNA.GH02439 PTHR11034:SF40 N-MYC DOWNSTREAM REGULATED BCDNA.GH02439 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 serine protease#PC00203 DROME|FlyBase=FBgn0086347|UniProtKB=Q23978 Q23978 Myo31DF PTHR13140:SF713 MYOSIN UNCONVENTIONAL MYOSIN ID ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cellular process#GO:0009987;actin filament-based movement#GO:0030048;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;transport#GO:0006810;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234 actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0032250|UniProtKB=Q9VKV5 Q9VKV5 holn1 PTHR13138:SF3 PROTEIN LIN1 CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0036321|UniProtKB=Q9VU22 Q9VU22 Dmel\CG14120 PTHR13966:SF19 ENDONUCLEASE RELATED DNA_RNA NON-SPECIFIC ENDONUCLEASE DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial membrane#GO:0031966;cytoplasm#GO:0005737;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0040798|UniProtKB=Q9VV08 Q9VV08 Dmel\CG13069 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0259832|UniProtKB=Q6IGM9 Q6IGM9 CG13191 PTHR13675:SF0 LYR MOTIF-CONTAINING PROTEIN 2 LYR MOTIF-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0002593|UniProtKB=P08570 P08570 RpLP1 PTHR45696:SF10 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 structural molecule activity#GO:0005198;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;structural constituent of ribosome#GO:0003735;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;ribonucleoprotein complex binding#GO:0043021;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;kinase activator activity#GO:0019209;binding#GO:0005488 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 DROME|FlyBase=FBgn0038928|UniProtKB=Q9V3B4 Q9V3B4 Fadd PTHR15077:SF9 FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN FADD FAS-ASSOCIATED DEATH DOMAIN PROTEIN Apoptosis signaling pathway#P00006>FADD#P00327;FAS signaling pathway#P00020>FADD#P00622 DROME|FlyBase=FBgn0000529|UniProtKB=Q04787 Q04787 bsh PTHR24327:SF41 HOMEOBOX PROTEIN BRAIN-SPECIFIC HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0052369|UniProtKB=Q9VSB2 Q9VSB2 CG7388 PTHR23327:SF42 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN C14F5.10C acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0052036|UniProtKB=Q9VT02 Q9VT02 CG3426 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0051849|UniProtKB=Q95RF3 Q95RF3 Mgat3 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0051231|UniProtKB=Q8IN79 Q8IN79 Dmel\CG31231 PTHR34491:SF69 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED CCDC113_CCDC96 COILED-COIL DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0035318|UniProtKB=Q9W039 Q9W039 Dmel\CG9018 PTHR12460:SF0 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN CID DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 DROME|FlyBase=FBgn0051219|UniProtKB=A8JR43 A8JR43 CG16731 PTHR24260:SF144 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED Toll pathway-drosophila#P06217>SPE#P06340 DROME|FlyBase=FBgn0038285|UniProtKB=Q9VFD6 Q9VFD6 Dmel\CG6974 PTHR10127:SF905 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0010531|UniProtKB=E1JH26 E1JH26 Ccs PTHR10003:SF86 SUPEROXIDE DISMUTASE CU-ZN -RELATED COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;molecular carrier activity#GO:0140104;cation binding#GO:0043169;metal ion binding#GO:0046872;catalytic activity#GO:0003824;copper ion binding#GO:0005507;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491 cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;response to reactive oxygen species#GO:0000302;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869 oxidoreductase#PC00176 DROME|FlyBase=FBgn0030245|UniProtKB=X2JB52 X2JB52 Dmel\CG1637 PTHR45867:SF3 PURPLE ACID PHOSPHATASE ACID PHOSPHATASE TYPE 7 phosphatase#PC00181 DROME|FlyBase=FBgn0040299|UniProtKB=Q8IPH8 Q8IPH8 Myo28B1 PTHR13140:SF872 MYOSIN MYOSIN VIIAA ISOFORM X1 microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cellular component organization#GO:0016043;sensory perception of sound#GO:0007605;actin cytoskeleton organization#GO:0030036;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular process#GO:0009987;actin filament-based movement#GO:0030048;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513 membrane#GO:0016020;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0283724|UniProtKB=Q9VZT7 Q9VZT7 Girdin PTHR18947:SF40 HOOK PROTEINS GIRDIN, ISOFORM A protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0033188|UniProtKB=Q961L4 Q961L4 Drat PTHR42683:SF98 ALDEHYDE REDUCTASE DEATH RESISTOR ADH DOMAIN CONTAINING TARGET, ISOFORM C oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 oxidoreductase#PC00176 DROME|FlyBase=FBgn0035240|UniProtKB=Q95T35 Q95T35 Ogdh2 PTHR23152:SF4 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0050481|UniProtKB=A1Z9J6 A1Z9J6 mRpL53 PTHR33618:SF1 39S RIBOSOMAL PROTEIN L53, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML53 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 DROME|FlyBase=FBgn0036973|UniProtKB=Q9VPH8 Q9VPH8 Rbbp5 PTHR44040:SF1 RETINOBLASTOMA-BINDING PROTEIN 5 RETINOBLASTOMA-BINDING PROTEIN 5 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;organelle lumen#GO:0043233;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0036213|UniProtKB=Q9VTP4 Q9VTP4 RpL10Ab PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0035776|UniProtKB=M9PEV1 M9PEV1 Dmel\CG8564 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0004574|UniProtKB=Q07327 Q07327 Rop PTHR11679:SF91 VESICLE PROTEIN SORTING-ASSOCIATED PROTEIN ROP binding#GO:0005488;SNARE binding#GO:0000149;syntaxin binding#GO:0019905;protein binding#GO:0005515 intracellular protein transport#GO:0006886;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;secretion by cell#GO:0032940;protein transport#GO:0015031;cellular localization#GO:0051641;regulation of biological process#GO:0050789;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;calcium-ion regulated exocytosis#GO:0017156;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916 secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0051288|UniProtKB=Q8IMT4 Q8IMT4 CG13665 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0010407|UniProtKB=Q24488 Q24488 Ror PTHR24416:SF611 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;axon#GO:0030424 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0051195|UniProtKB=Q8IN49 Q8IN49 Dmel\CG31195 PTHR32546:SF25 G-PROTEIN COUPLED RECEPTOR 158-RELATED MIP05539P G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0033348|UniProtKB=Q8SYP8 Q8SYP8 Spt PTHR18914:SF33 ALPHA CATENIN RE47911P-RELATED protein binding#GO:0005515;beta-catenin binding#GO:0008013;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;cell migration#GO:0016477;cell motility#GO:0048870 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;anchoring junction#GO:0070161;adherens junction#GO:0005912 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0023094|UniProtKB=O61734 O61734 cyc PTHR23042:SF99 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS PROTEIN CYCLE transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 Circadian clock system#P00015>BMAL1#P00506;Circadian clock system#P00015>bmal1#G01500;Circadian clock system#P00015>bmal1#G01504 DROME|FlyBase=FBgn0034558|UniProtKB=Q9W2Q5 Q9W2Q5 Cib2 PTHR45791:SF6 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 2 cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;monoatomic ion homeostasis#GO:0050801;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771 DROME|FlyBase=FBgn0033869|UniProtKB=Q7K2P1 Q7K2P1 Cpr50Cb PTHR12236:SF100 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 50CA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0034053|UniProtKB=Q9V7G5 Q9V7G5 Cyp4aa1 PTHR24291:SF177 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4AA1-RELATED oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0039904|UniProtKB=Q9V4C8 Q9V4C8 Hcf PTHR46003:SF1 HOST CELL FACTOR HOST CELL FACTOR transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0036763|UniProtKB=Q9VVL8 Q9VVL8 TrpRS-m PTHR43766:SF5 TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0034766|UniProtKB=Q86BF9 Q86BF9 Obp59a PTHR21066:SF9 ODORANT-BINDING PROTEIN 59A-RELATED ODORANT-BINDING PROTEIN 59A DROME|FlyBase=FBgn0286976|UniProtKB=Q9VNN0 Q9VNN0 Osi10a PTHR21879:SF27 FI03362P-RELATED-RELATED OSIRIS 10A cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0260632|UniProtKB=P15330 P15330 dl PTHR24169:SF28 NUCLEAR FACTOR NF-KAPPA-B PROTEIN DORSAL-RELATED IMMUNITY FACTOR DIF-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 Rel homology transcription factor#PC00252;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Toll pathway-drosophila#P06217>DL#P06344;Toll receptor signaling pathway#P00054>NFkappaB#P01354 DROME|FlyBase=FBgn0286980|UniProtKB=E1JIB2 E1JIB2 Iyd PTHR23026:SF129 NADPH NITROREDUCTASE IODOTYROSINE DEIODINASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;reductase#PC00198 DROME|FlyBase=FBgn0052423|UniProtKB=Q8MSV2 Q8MSV2 shep PTHR24012:SF796 RNA BINDING PROTEIN PROTEIN ALAN SHEPARD RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030855|UniProtKB=Q9VX34 Q9VX34 cg5800 PTHR24031:SF54 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX10-RELATED macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0032645|UniProtKB=Q9VJC8 Q9VJC8 Dmel\CG15142 PTHR22607:SF3 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CDK2-ASSOCIATED PROTEIN 1, ISOFORM B intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase modulator#PC00140;kinase inhibitor#PC00139 DROME|FlyBase=FBgn0053769|UniProtKB=Q4ABH7 Q4ABH7 CG14458 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0039223|UniProtKB=Q9VC40 Q9VC40 Dmel\CG5805 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 branched-chain amino acid transmembrane transporter activity#GO:0015658;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nitrogen compound transport#GO:0071705;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;branched-chain amino acid transport#GO:0015803 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0033475|UniProtKB=Q7JW66 Q7JW66 cg12129 PTHR13360:SF1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0011760|UniProtKB=Q24117 Q24117 ctp PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC-RELATED binding#GO:0005488;protein binding#GO:0005515 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0004587|UniProtKB=P26686 P26686 B52 PTHR23003:SF51 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE-ARGININE PROTEIN 55 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0039380|UniProtKB=Q9VBL2 Q9VBL2 Dmel\CG5890 PTHR23055:SF186 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG-LIKE PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 calmodulin-related#PC00061 DROME|FlyBase=FBgn0035205|UniProtKB=Q7K0X3 Q7K0X3 Ctr9 PTHR14027:SF2 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368 Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0052591|UniProtKB=Q8IR43 Q8IR43 NEST:bs18d12 PTHR21490:SF2 ENKURIN-RELATED ENKURIN DOMAIN-CONTAINING PROTEIN 1 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0000017|UniProtKB=P00522 P00522 Abl PTHR24418:SF162 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 DROME|FlyBase=FBgn0038467|UniProtKB=Q9VEP6 Q9VEP6 Adsl PTHR43172:SF1 ADENYLOSUCCINATE LYASE ADENYLOSUCCINATE LYASE catalytic activity#GO:0003824;lyase activity#GO:0016829 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 lyase#PC00144;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>Adenosuccinate lyase#P02901;De novo purine biosynthesis#P02738>5-Phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole lyase#P02892 DROME|FlyBase=FBgn0037068|UniProtKB=Q9VP55 Q9VP55 Cpr78Cb PTHR10380:SF238 CUTICLE PROTEIN CUTICULAR PROTEIN 65EA-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0035760|UniProtKB=Q9VS44 Q9VS44 Dmel\CG8607 PTHR21381:SF3 ZGC:162297 SGC REGION PROTEIN SGCQ-RELATED DROME|FlyBase=FBgn0042098|UniProtKB=Q9I7V4 Q9I7V4 SP22 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0033649|UniProtKB=B9ZW35 B9ZW35 pyr PTHR48233:SF4 MUCIN 4B, ISOFORM B-RELATED MUCIN 4B, ISOFORM B-RELATED DROME|FlyBase=FBgn0028686|UniProtKB=Q9V405 Q9V405 Rpt3 PTHR23073:SF155 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6B macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>19S proteasome#P01494;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0051163|UniProtKB=A0A0B4KHV7 A0A0B4KHV7 SKIP PTHR12301:SF8 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 DROME|FlyBase=FBgn0267430|UniProtKB=A0A126GUQ2 A0A126GUQ2 Pzl PTHR13167:SF48 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to mechanical stimulus#GO:0009612;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;biological regulation#GO:0065007;detection of mechanical stimulus#GO:0050982;cellular response to abiotic stimulus#GO:0071214;regulation of membrane potential#GO:0042391;regulation of biological quality#GO:0065008;response to external stimulus#GO:0009605 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0031668|UniProtKB=Q9VMV7 Q9VMV7 Dmel\CG31917 PTHR13093:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1 ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0035844|UniProtKB=Q9VSE3 Q9VSE3 Dmel\CG13676 PTHR22933:SF40 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0030684|UniProtKB=Q9VXQ1 Q9VXQ1 Dmel\CG8260 PTHR22667:SF0 AT01380P-RELATED AT01380P-RELATED DROME|FlyBase=FBgn0024958|UniProtKB=Q9VCV4 Q9VCV4 Irp-1A PTHR11670:SF75 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER CYTOPLASMIC ACONITATE HYDRATASE iron-sulfur cluster binding#GO:0051536;lyase activity#GO:0016829;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 DROME|FlyBase=FBgn0086384|UniProtKB=Q24564 Q24564 Mer PTHR23281:SF39 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN_EZRIN_RADIXIN HOMOLOG 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;actin binding#GO:0003779;integrin binding#GO:0005178;cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;negative regulation of cell population proliferation#GO:0008285;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of anatomical structure morphogenesis#GO:0022603;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of cell population proliferation#GO:0042127;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;filopodium#GO:0030175;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0037526|UniProtKB=Q8SXK2 Q8SXK2 ArgRS-m PTHR11956:SF11 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0034885|UniProtKB=A0A0B4KFZ1 A0A0B4KFZ1 Eglp4 PTHR19139:SF270 AQUAPORIN TRANSPORTER ENTOMOGLYCEROPORIN 1-RELATED passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;channel activity#GO:0015267 establishment of localization#GO:0051234;water transport#GO:0006833;localization#GO:0051179;fluid transport#GO:0042044;transport#GO:0006810 apical part of cell#GO:0045177;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;apical plasma membrane#GO:0016324;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 DROME|FlyBase=FBgn0051644|UniProtKB=X2JD93 X2JD93 COX6CL PTHR48416:SF1 CYTOCHROME C OXIDASE SUBUNIT 6C CYTOCHROME C OXIDASE SUBUNIT 6C organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031868|UniProtKB=Q9VM71 Q9VM71 Rat1 PTHR12341:SF41 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 2 catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 DROME|FlyBase=FBgn0051207|UniProtKB=Q8MSJ6 Q8MSJ6 CG7096 PTHR11008:SF32 PROTEIN TAKEOUT-LIKE PROTEIN GH08336P-RELATED rhythmic process#GO:0048511;circadian rhythm#GO:0007623 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0040322|UniProtKB=Q9VVR4 Q9VVR4 GNBP2 PTHR10963:SF70 GLYCOSYL HYDROLASE-RELATED GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glucosidase#PC00108;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0003430|UniProtKB=P32030 P32030 slp1 PTHR11829:SF363 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN TRANSCRIPTION FACTOR SLP1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0003557|UniProtKB=Q9Y0H4 Q9Y0H4 Su(dx) PTHR11254:SF429 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SU(DX) acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0027609|UniProtKB=Q9Y165 Q9Y165 morgue PTHR24068:SF565 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0037358|UniProtKB=Q9VNF9 Q9VNF9 elm PTHR46002:SF5 EG:114D9.1 PROTEIN-RELATED EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0037608|UniProtKB=Q9VHN6 Q9VHN6 mRpL19 PTHR15680:SF21 RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0000146|UniProtKB=O76922 O76922 aub PTHR22891:SF189 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN AUBERGINE-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 piRNA processing#GO:0034587;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;male gamete generation#GO:0048232;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0030341|UniProtKB=Q9VYT6 Q9VYT6 p24-1 PTHR22811:SF210 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN P24-RELATED-1, ISOFORM A cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505 membrane traffic protein#PC00150;vesicle coat protein#PC00235 DROME|FlyBase=FBgn0032295|UniProtKB=Q9VKQ7 Q9VKQ7 Dmel\CG12299 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0015569|UniProtKB=A0A0B4K6L1 A0A0B4K6L1 alpha-Est10 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0033376|UniProtKB=Q6NNB2 Q6NNB2 SKI3 PTHR15704:SF7 SUPERKILLER 3 PROTEIN-RELATED SUPERKILLER COMPLEX PROTEIN 3 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0053230|UniProtKB=Q7KVB0 Q7KVB0 Dmel\CG33230 PTHR13271:SF165 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE MIP03820P lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;methyltransferase#PC00155 DROME|FlyBase=FBgn0036196|UniProtKB=Q9VTM4 Q9VTM4 Dmel\CG11658 PTHR13123:SF7 LD30288P LD30288P protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 DROME|FlyBase=FBgn0023540|UniProtKB=O46052 O46052 EG:152A3.3 PTHR22739:SF7 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED EG:152A3.3 PROTEIN-RELATED regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of signal transduction#GO:0009967;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;regulation of transcription by RNA polymerase II#GO:0006357 membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292 DROME|FlyBase=FBgn0035631|UniProtKB=Q9VRP3 Q9VRP3 Txl PTHR46115:SF1 THIOREDOXIN-LIKE PROTEIN 1 THIOREDOXIN-LIKE PROTEIN 1 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122 DROME|FlyBase=FBgn0036551|UniProtKB=Q9VUW2 Q9VUW2 IMP PTHR20854:SF25 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 DROME|FlyBase=FBgn0015296|UniProtKB=Q9V3C8 Q9V3C8 Shc PTHR10337:SF11 SHC TRANSFORMING PROTEIN DSHC PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Shc#P01175;FGF signaling pathway#P00021>Shc#P00639;Integrin signalling pathway#P00034>Shc#P00949;EGF receptor signaling pathway#P00018>Shc#P00554 DROME|FlyBase=FBgn0004106|UniProtKB=P23572 P23572 Cdk1 PTHR24056:SF334 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;mitotic cell cycle phase transition#GO:0044772;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;signal transduction#GO:0007165;response to stress#GO:0006950 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Cdc2#P04634 DROME|FlyBase=FBgn0039755|UniProtKB=Q9VA93 Q9VA93 Dmel\CG15531 PTHR11351:SF26 ACYL-COA DESATURASE FATTY ACID DESATURASE DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;unsaturated fatty acid biosynthetic process#GO:0006636;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;monocarboxylic acid biosynthetic process#GO:0072330 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 DROME|FlyBase=FBgn0035763|UniProtKB=Q9VS47 Q9VS47 mrva PTHR23512:SF13 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LYSOSOMAL DIPEPTIDE TRANSPORTER MFSD1 lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 DROME|FlyBase=FBgn0031005|UniProtKB=Q9VWJ7 Q9VWJ7 Hs3st-B PTHR10605:SF72 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE 3-O SULFOTRANSFERASE-B, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0003068|UniProtKB=P07663 P07663 per PTHR11269:SF16 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN protein binding#GO:0005515;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription factor binding#GO:0008134 response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;response to radiation#GO:0009314;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;rhythmic process#GO:0048511;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217 Circadian clock system#P00015>Per#P00504;Circadian clock system#P00015>per#G01499;Circadian clock system#P00015>per#G01503 DROME|FlyBase=FBgn0263855|UniProtKB=A1Z6I7 A1Z6I7 BubR1 PTHR14030:SF29 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;sister chromatid cohesion#GO:0007062;cell communication#GO:0007154;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;meiotic sister chromatid cohesion#GO:0051177;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816 membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0039930|UniProtKB=Q9V492 Q9V492 Mpv17 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0000014|UniProtKB=P29555 P29555 abd-A PTHR45659:SF25 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN ABDOMINAL-A transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;pattern specification process#GO:0007389;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0028837|UniProtKB=Q9VCY3 Q9VCY3 CSN6 PTHR10540:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 6 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 translation initiation factor#PC00224 DROME|FlyBase=FBgn0031252|UniProtKB=Q9VPP5 Q9VPP5 CG13690 PTHR10954:SF7 RIBONUCLEASE H2 SUBUNIT A RIBONUCLEASE H2 SUBUNIT A hydrolase activity#GO:0016787;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;mismatch repair#GO:0006298;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 DROME|FlyBase=FBgn0004868|UniProtKB=Q9VLB7 Q9VLB7 Gdi PTHR11787:SF8 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 transport#GO:0006810;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0037553|UniProtKB=E1JJ89 E1JJ89 CT41336 PTHR46473:SF23 GH08155P GH08155P DROME|FlyBase=FBgn0011573|UniProtKB=Q24276 Q24276 Cdc37 PTHR12800:SF4 CDC37-RELATED HSP90 CO-CHAPERONE CDC37 protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 metabolic process#GO:0008152;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;regulation of protein stability#GO:0031647;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chaperone#PC00072 DROME|FlyBase=FBgn0037931|UniProtKB=Q9VGK1 Q9VGK1 CG17822 PTHR24376:SF216 ZINC FINGER PROTEIN DRACULIN-LIKE 3 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0061356|UniProtKB=A1Z8D3 A1Z8D3 Hao PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 oxidoreductase#PC00176 DROME|FlyBase=FBgn0031763|UniProtKB=Q9VMJ2 Q9VMJ2 Dmel\CG13996 PTHR12573:SF4 AT09986P-RELATED AT09986P-RELATED DROME|FlyBase=FBgn0024980|UniProtKB=Q7KVY7 Q7KVY7 Syx4 PTHR19957:SF19 SYNTAXIN SYNTAXIN-4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;cellular component organization#GO:0016043;vesicle fusion#GO:0006906 membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cell junction#GO:0030054;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;synapse#GO:0045202;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 DROME|FlyBase=FBgn0014949|UniProtKB=Q9VCY0 Q9VCY0 btn PTHR24328:SF7 HOMEOBOX PROTEIN MOX BUTTONLESS DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0000546|UniProtKB=P34021 P34021 EcR PTHR24082:SF507 NUCLEAR HORMONE RECEPTOR BILE ACID RECEPTOR-RELATED transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;chemical homeostasis#GO:0048878;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;lipid homeostasis#GO:0055088;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cholesterol homeostasis#GO:0042632;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0041233|UniProtKB=Q9W1N6 Q9W1N6 Gr59e PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030037|UniProtKB=Q9W3F7 Q9W3F7 Miga PTHR21508:SF5 MITOGUARDIN MITOGUARDIN mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043 DROME|FlyBase=FBgn0262166|UniProtKB=Q7K5N4 Q7K5N4 caly PTHR10589:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE BAP1 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0031831|UniProtKB=Q9VMB8 Q9VMB8 COX5BL PTHR10122:SF0 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060 mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transporter complex#GO:1990351;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0004654|UniProtKB=P41572 P41572 Pgd PTHR11811:SF25 6-PHOSPHOGLUCONATE DEHYDROGENASE 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;phosphogluconate dehydrogenase (decarboxylating) activity#GO:0004616;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265 purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 Pentose phosphate pathway#P02762>Gluconate Dehydrogenase#P03070 DROME|FlyBase=FBgn0034289|UniProtKB=A1ZB18 A1ZB18 Dmel\CG10910 PTHR36910:SF10 FAMILY NOT NAMED SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0001991|UniProtKB=Q24270 Q24270 Ca-alpha1D PTHR45628:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE D SUBUNIT ALPHA-1 voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;transport#GO:0006810;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241 5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 DROME|FlyBase=FBgn0260466|UniProtKB=Q9VDQ0 Q9VDQ0 Indy2 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;citrate transmembrane transporter activity#GO:0015137;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;tricarboxylic acid transport#GO:0006842;citrate transport#GO:0015746;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0069913|UniProtKB=Q9W144 Q9W144 Tex9 PTHR23313:SF0 TSEC1-RELATED TESTIS-EXPRESSED PROTEIN 9 actin or actin-binding cytoskeletal protein#PC00041;actin binding motor protein#PC00040 DROME|FlyBase=FBgn0035770|UniProtKB=Q8IQ80 Q8IQ80 pst PTHR21115:SF0 GH06117P-RELATED GH06117P-RELATED DROME|FlyBase=FBgn0029977|UniProtKB=Q9W3M9 Q9W3M9 hdm PTHR21166:SF2 CELL DIVISION CONTROL PROTEIN 24 OB DOMAIN-CONTAINING PROTEIN-RELATED MEIOSIS-SPECIFIC WITH OB DOMAIN-CONTAINING PROTEIN exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408 cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;response to stimulus#GO:0050896;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;organelle fission#GO:0048285;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;homologous recombination#GO:0035825;reproductive process#GO:0022414;DNA damage response#GO:0006974;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0037109|UniProtKB=Q9VP05 Q9VP05 MED1 PTHR12881:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 DROME|FlyBase=FBgn0261573|UniProtKB=Q59E36 Q59E36 CoRest PTHR16089:SF28 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0262570|UniProtKB=C0PDF1 C0PDF1 CG4827-RA PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0036727|UniProtKB=Q9VVH4 Q9VVH4 SecCl PTHR18945:SF843 NEUROTRANSMITTER GATED ION CHANNEL PH-SENSITIVE CHLORIDE CHANNEL 2 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0285896|UniProtKB=Q09147 Q09147 btl PTHR24416:SF550 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATED catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0031940|UniProtKB=Q9VLY1 Q9VLY1 Dmel\CG7214 PTHR12336:SF0 ADULT CUTICLE PROTEIN 1-RELATED ADULT CUTICLE PROTEIN 1-RELATED DROME|FlyBase=FBgn0032195|UniProtKB=Q9VL22 Q9VL22 Bcs1 PTHR23070:SF255 BCS1 AAA-TYPE ATPASE MITOCHONDRIAL CHAPERONE BCS1 establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 DROME|FlyBase=FBgn0035113|UniProtKB=Q9W0T5 Q9W0T5 pyx PTHR24161:SF130 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED TRANSIENT RECEPTOR POTENTIAL CHANNEL PYREXIA protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039889|UniProtKB=H9XVM3 H9XVM3 Arl4 PTHR11711:SF186 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 11 guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 DROME|FlyBase=FBgn0035281|UniProtKB=Q9W077 Q9W077 Cpr62Bc PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0029868|UniProtKB=Q9W402 Q9W402 ND-B16.6 PTHR12966:SF0 NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0050421|UniProtKB=Q9W117 Q9W117 Usp15-31 PTHR21646:SF14 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITINYL HYDROLASE 1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 cysteine protease#PC00081 DROME|FlyBase=FBgn0011327|UniProtKB=Q9XZ61 Q9XZ61 Uch-L5 PTHR10589:SF51 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of chromosome organization#GO:0033044 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0035432|UniProtKB=M9PEG6 M9PEG6 ZnT63C PTHR45820:SF10 FI23527P1 ZINC TRANSPORTER 63C, ISOFORM F transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;monoatomic cation transmembrane transport#GO:0098655;detoxification#GO:0098754;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;response to chemical#GO:0042221;response to metal ion#GO:0010038;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0027616|UniProtKB=Q9VZQ1 Q9VZQ1 Ythdc1 PTHR12357:SF3 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING PROTEIN 1 protein-RNA adaptor activity#GO:0140517;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of mRNA metabolic process#GO:1903311;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0003984|UniProtKB=Q94918 Q94918 vn PTHR11100:SF12 HEREGULIN-NEUREGULIN FAMILY MEMBER PROTEIN VEIN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;animal organ development#GO:0048513;anatomical structure development#GO:0048856;cell communication#GO:0007154;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 DROME|FlyBase=FBgn0032219|UniProtKB=Q9VKZ5 Q9VKZ5 Dmel\CG4995 PTHR45624:SF61 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174 establishment of localization#GO:0051234;intracellular transport#GO:0046907;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;cellular localization#GO:0051641;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 transporter#PC00227 DROME|FlyBase=FBgn0037730|UniProtKB=Q9VH93 Q9VH93 Dmel\CG9444 PTHR11654:SF678 OLIGOPEPTIDE TRANSPORTER-RELATED PEPTIDE TRANSPORTER FAMILY 1 dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;import across plasma membrane#GO:0098739;transport#GO:0006810;oligopeptide transport#GO:0006857;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;dipeptide transport#GO:0042938;import into cell#GO:0098657;localization#GO:0051179 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0037488|UniProtKB=Q9VI81 Q9VI81 Dmel\CG14607 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0085382|UniProtKB=A0A0B4LI09 A0A0B4LI09 CG5566 PTHR45080:SF39 CONTACTIN 5 FASCICLIN-2-LIKE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043 axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944 DROME|FlyBase=FBgn0053544|UniProtKB=A1ZAJ5 A1ZAJ5 Vkor PTHR14519:SF9 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN-K-EPOXIDE REDUCTASE (WARFARIN-SENSITIVE) oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 vitamin K metabolic process#GO:0042373;ketone metabolic process#GO:0042180;metabolic process#GO:0008152;cellular process#GO:0009987 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032167|UniProtKB=Q9VL61 Q9VL61 Dmel\CG5853 PTHR48041:SF26 ABC TRANSPORTER G FAMILY MEMBER 28 FI22810P1 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0053523|UniProtKB=M9PBR6 M9PBR6 CG10977 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle membrane contact site#GO:0044232 DROME|FlyBase=FBgn0027583|UniProtKB=Q9Y140 Q9Y140 CG7601 PTHR44196:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B PEROXISOMAL REDUCTASE ACTIVATING PPAR-GAMMA cellular anatomical structure#GO:0110165;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 DROME|FlyBase=FBgn0035134|UniProtKB=Q9W0R2 Q9W0R2 Dmel\CG1231 PTHR46786:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 3 ZINC FINGER MATRIN-TYPE PROTEIN 3 RNA metabolism protein#PC00031;RNA processing factor#PC00147 p53 pathway#P00059>PAG608#G04690 DROME|FlyBase=FBgn0053105|UniProtKB=Q86BA5 Q86BA5 p24-2 PTHR22811:SF14 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN LP01981P-RELATED cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0000233|UniProtKB=Q24266 Q24266 btd PTHR23235:SF1 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0261791|UniProtKB=Q9VXE0 Q9VXE0 SNRPG PTHR10553:SF2 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cytoplasmic ribonucleoprotein granule#GO:0036464;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U12-type spliceosomal complex#GO:0005689;nucleus#GO:0005634;U1 snRNP#GO:0005685;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;SMN-Sm protein complex#GO:0034719;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2 snRNP#GO:0005686;P granule#GO:0043186;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0039233|UniProtKB=Q9VC28 Q9VC28 anon-WO0118547.410 PTHR23415:SF4 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0011666|UniProtKB=Q8IMS8 Q8IMS8 msi PTHR48032:SF4 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 FI20028P1 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0263852|UniProtKB=Q9VLM5 Q9VLM5 Dad1 PTHR10705:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0033203|UniProtKB=Q8MZG9 Q8MZG9 Dmel\CG2070 PTHR24320:SF294 RETINOL DEHYDROGENASE NADP-RETINOL DEHYDROGENASE-RELATED alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0034902|UniProtKB=Q9W1K0 Q9W1K0 CG5532 PTHR12668:SF58 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14 HOMOLOG mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0003638|UniProtKB=P12297 P12297 su(w[a]) PTHR13161:SF15 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;alternative mRNA splicing, via spliceosome#GO:0000380;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0052521|UniProtKB=Q9VRF7 Q9VRF7 Mnr PTHR39956:SF1 GH09530P-RELATED GH09530P-RELATED DROME|FlyBase=FBgn0031110|UniProtKB=Q9VR95 Q9VR95 Obp19b PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0024182|UniProtKB=Q9VRH6 Q9VRH6 waw PTHR43512:SF7 TRANSLATION FACTOR GUF1-RELATED TRANSLATION FACTOR GUF1, MITOCHONDRIAL protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of translation#GO:0045727;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 translation initiation factor#PC00224 DROME|FlyBase=FBgn0013746|UniProtKB=Q94899 Q94899 alien PTHR10678:SF3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 COP9 SIGNALOSOME COMPLEX SUBUNIT 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0039366|UniProtKB=Q9VBM8 Q9VBM8 Dmel\CG17198 PTHR22883:SF511 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 developmental process#GO:0032502;protein targeting to membrane#GO:0006612;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;cellular process#GO:0009987;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;developmental maturation#GO:0021700;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein targeting#GO:0006605 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036460|UniProtKB=M9NE98 M9NE98 Dmel\CG5114 PTHR19857:SF27 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 cellular process#GO:0009987;cell adhesion#GO:0007155;cell migration#GO:0016477;cell motility#GO:0048870 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0039938|UniProtKB=Q59DN5 Q59DN5 Sox102F PTHR45789:SF6 FI18025P1 FI18025P1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0030753|UniProtKB=Q9VXF9 Q9VXF9 rngo PTHR12917:SF1 ASPARTYL PROTEASE DDI-RELATED AT13091P catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aspartic protease#PC00053;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0016920|UniProtKB=Q9VMR4 Q9VMR4 nompC PTHR24121:SF35 NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED NO MECHANORECEPTOR POTENTIAL C, ISOFORM H system process#GO:0003008;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0000996|UniProtKB=Q7JVY2 Q7JVY2 dup PTHR28637:SF1 DNA REPLICATION FACTOR CDT1 DNA REPLICATION FACTOR CDT1 nucleic acid binding#GO:0003676;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;DNA binding#GO:0003677 negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174;cell communication#GO:0007154;regulation of DNA replication#GO:0006275;intracellular signal transduction#GO:0035556;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell cycle#GO:0051726 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0036217|UniProtKB=Q9VTQ1 Q9VTQ1 BcDNA:AT16953 PTHR11266:SF131 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 FI08002P-RELATED membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 transporter#PC00227 DROME|FlyBase=FBgn0035141|UniProtKB=Q9W0Q2 Q9W0Q2 Cypl PTHR45625:SF18 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|FlyBase=FBgn0039379|UniProtKB=Q9VBL3 Q9VBL3 Dmel\CG5886 PTHR16127:SF13 TAXILIN GH01188P membrane traffic protein#PC00150 DROME|FlyBase=FBgn0038673|UniProtKB=Q9VE11 Q9VE11 CG14286 PTHR13602:SF2 UPF0488 PROTEIN C8ORF33 UPF0488 PROTEIN C8ORF33 DROME|FlyBase=FBgn0031000|UniProtKB=Q9VWK2 Q9VWK2 Muc18B PTHR15817:SF2 STG PROTEIN SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 15 DROME|FlyBase=FBgn0011771|UniProtKB=P55162 P55162 Hem PTHR12093:SF12 NCK-ASSOCIATED PROTEIN 1 MEMBRANE-ASSOCIATED PROTEIN HEM cell projection assembly#GO:0030031;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;cellular component assembly#GO:0022607;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;system development#GO:0048731;cortical actin cytoskeleton organization#GO:0030866;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0036929|UniProtKB=Q9VW70 Q9VW70 FBpp0074674 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0031990|UniProtKB=Q9VLS7 Q9VLS7 PAPLA1 PTHR23509:SF50 PA-PL1 PHOSPHOLIPASE FAMILY LD21067P phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 phospholipase#PC00186;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0011297|UniProtKB=Q27333 Q27333 Alg3 PTHR12646:SF0 NOT56 - RELATED DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0053238|UniProtKB=Q7KV14 Q7KV14 Ste:CG33238 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0014411|UniProtKB=Q9W552 Q9W552 Vps26 PTHR12233:SF1 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26 cytosolic transport#GO:0016482;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;retromer complex#GO:0030904;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0033169|UniProtKB=Q7JX95 Q7JX95 Dmel\CG11123 PTHR13102:SF0 NUCLEOLAR PROTEIN 9 NUCLEOLAR PROTEIN 9 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;nuclear export#GO:0051168;nuclear transport#GO:0051169;localization#GO:0051179;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;establishment of organelle localization#GO:0051656;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0263594|UniProtKB=Q9VN21 Q9VN21 lost PTHR13017:SF0 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE-RELATED METHENYLTETRAHYDROFOLATE SYNTHASE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;ligase#PC00142 DROME|FlyBase=FBgn0038683|UniProtKB=Q9VDZ7 Q9VDZ7 CG117799 PTHR10721:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743 transporter#PC00227 DROME|FlyBase=FBgn0262473|UniProtKB=P08953 P08953 Tl PTHR24365:SF556 TOLL-LIKE RECEPTOR PROTEIN TOLL-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;signal transduction#GO:0007165;immune response#GO:0006955;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;response to external biotic stimulus#GO:0043207;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;immune system process#GO:0002376 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Toll pathway-drosophila#P06217>TL#P06337;Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0052227|UniProtKB=Q9VWA7 Q9VWA7 gogo PTHR16311:SF3 THROMBOSPONDIN TYPE I DOMAIN-CONTAINING 1 THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;cell periphery#GO:0071944 DROME|FlyBase=FBgn0034817|UniProtKB=Q9W1V1 Q9W1V1 Art7 PTHR11006:SF4 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 7 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031681|UniProtKB=Q6WV17 Q6WV17 Pgant5 PTHR11675:SF101 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5 glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0037391|UniProtKB=Q960F7 Q960F7 Gtpbp2 PTHR43721:SF3 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 2 translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 translation elongation factor#PC00222 DROME|FlyBase=FBgn0033250|UniProtKB=D0Z756 D0Z756 CG14762-RA PTHR45617:SF185 LEUCINE RICH REPEAT FAMILY PROTEIN MIP14966P scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035726|UniProtKB=Q9VS02 Q9VS02 Dmel\CG9953 PTHR11010:SF117 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED SERINE PROTEASE 16 serine protease#PC00203 DROME|FlyBase=FBgn0035462|UniProtKB=Q9VZM7 Q9VZM7 IntS10 PTHR16055:SF2 INTEGRATOR COMPLEX SUBUNIT 10 INTEGRATOR COMPLEX SUBUNIT 10 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 DROME|FlyBase=FBgn0003301|UniProtKB=P32870 P32870 Adcy1 PTHR45627:SF26 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 1 catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;CCKR signaling map#P06959>Adenylate cyclase#P07127;Gonadotropin-releasing hormone receptor pathway#P06664>AC#P06699;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760 DROME|FlyBase=FBgn0026090|UniProtKB=O96824 O96824 Lamtor5 PTHR13342:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR5 RAGULATOR COMPLEX PROTEIN LAMTOR5 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;positive regulation of TORC1 signaling#GO:1904263;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;lysosome#GO:0005764 DROME|FlyBase=FBgn0040336|UniProtKB=Q9V3X4 Q9V3X4 Seipin PTHR21212:SF0 BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN SEIPIN lipid storage#GO:0019915;cellular process#GO:0009987;organelle organization#GO:0006996;lipid droplet organization#GO:0034389;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 DROME|FlyBase=FBgn0037419|UniProtKB=Q9VNN2 Q9VNN2 Osi12 PTHR21879:SF12 FI03362P-RELATED-RELATED OSIRIS 12 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0036010|UniProtKB=Q9VT09 Q9VT09 Ir67a PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0034474|UniProtKB=A1ZBQ4 A1ZBQ4 Obp56g PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0033778|UniProtKB=Q961J5 Q961J5 Balat PTHR24064:SF659 SOLUTE CARRIER FAMILY 22 MEMBER BETA-ALANINE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0036236|UniProtKB=Q9VTS1 Q9VTS1 Dmel\CG6931 PTHR31854:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0050392|UniProtKB=Q8MLW4 Q8MLW4 Dmel\CG30392 PTHR10219:SF43 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;phospholipid binding#GO:0005543;ion binding#GO:0043167;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;ceramide transport#GO:0035627;membrane organization#GO:0061024;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;cellular process#GO:0009987 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0031249|UniProtKB=Q9VPN8 Q9VPN8 SP103 PTHR24276:SF99 POLYSERASE-RELATED AT26814P-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0037296|UniProtKB=Q8T915 Q8T915 Prosbeta2R2 PTHR11599:SF44 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0263400|UniProtKB=A0A0B4K6S5 A0A0B4K6S5 Dmel\CG43446 PTHR37445:SF3 PROTEIN CBG24663 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0030937|UniProtKB=Q9VWS8 Q9VWS8 Dmel\CG15042 PTHR22948:SF80 TUDOR DOMAIN CONTAINING PROTEIN KRIMPER FIRST TUDOR DOMAIN-CONTAINING PROTEIN-RELATED scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0023216|UniProtKB=O46043 O46043 Parg PTHR12837:SF15 POLY ADP-RIBOSE GLYCOHYDROLASE POLY(ADP-RIBOSE) GLYCOHYDROLASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;regulation of cellular response to stress#GO:0080135;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;regulation of DNA metabolic process#GO:0051052;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;macromolecule metabolic process#GO:0043170;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;regulation of primary metabolic process#GO:0080090;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 glycosidase#PC00110 DROME|FlyBase=FBgn0037472|UniProtKB=Q9VI64 Q9VI64 Dmel\CG10098 PTHR12994:SF17 SECERNIN LD30995P DROME|FlyBase=FBgn0035007|UniProtKB=Q9W170 Q9W170 anon-WO0140519.253 PTHR11071:SF594 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0033038|UniProtKB=A1Z6H6 A1Z6H6 Mipep PTHR11804:SF79 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED MITOCHONDRIAL INTERMEDIATE PEPTIDASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0052703|UniProtKB=Q9W354 Q9W354 Erk7 PTHR24055:SF79 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 15 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 PDGF signaling pathway#P00047>ERK#P01143;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;EGF receptor signaling pathway#P00018>ERK1-2#P00543 DROME|FlyBase=FBgn0035520|UniProtKB=Q9VZF0 Q9VZF0 Dmel\CG11586 PTHR45986:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 2 ZINC FINGER MATRIN-TYPE PROTEIN 2 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA processing factor#PC00147 DROME|FlyBase=FBgn0263873|UniProtKB=Q9VIQ9 Q9VIQ9 Nav PTHR12784:SF28 STEERIN PROTEIN NEURON NAVIGATOR animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731 DROME|FlyBase=FBgn0045759|UniProtKB=Q9VS05 Q9VS05 bin PTHR46262:SF2 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN BINIOU sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0029813|UniProtKB=Q9W469 Q9W469 AgmNAT PTHR20905:SF33 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0031822|UniProtKB=Q9VMC8 Q9VMC8 Phf5a PTHR13120:SF0 PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0037098|UniProtKB=M9PGC5 M9PGC5 Wnk PTHR13902:SF177 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;molecular function inhibitor activity#GO:0140678;protein kinase activity#GO:0004672;channel regulator activity#GO:0016247;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674 regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878;regulation of transport#GO:0051049;regulation of localization#GO:0032879;monoatomic ion homeostasis#GO:0050801;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;signaling#GO:0023052;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0004921|UniProtKB=P38040 P38040 Ggamma1 PTHR13809:SF48 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA-RELATED hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell division#GO:0051301;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell population proliferation#GO:0008283;cell communication#GO:0007154;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;signal transduction#GO:0007165;cellular process#GO:0009987;asymmetric cell division#GO:0008356;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073 DROME|FlyBase=FBgn0286222|UniProtKB=Q9W3X6 Q9W3X6 Fum1 PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 DROME|FlyBase=FBgn0051866|UniProtKB=Q8IPA1 Q8IPA1 Ada1-2 PTHR21277:SF5 TRANSCRIPTIONAL ADAPTER 1 TRANSCRIPTIONAL ADAPTER 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;SAGA complex#GO:0000124;chromatin#GO:0000785;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DROME|FlyBase=FBgn0036462|UniProtKB=Q9VUJ0 Q9VUJ0 mRpL39 PTHR42753:SF9 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN ML39 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0261848|UniProtKB=X2JAR4 X2JAR4 Dmel\CG42780 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0052451|UniProtKB=M9PG15 M9PG15 SPoCk PTHR42861:SF29 CALCIUM-TRANSPORTING ATPASE P-TYPE CA(2+) TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068 DROME|FlyBase=FBgn0001138|UniProtKB=P91623 P91623 grn PTHR10071:SF340 TRANSCRIPTION FACTOR GATA FAMILY MEMBER FI19405P1-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036327|UniProtKB=Q9VU28 Q9VU28 Mdh2c PTHR11540:SF76 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092 DROME|FlyBase=FBgn0259734|UniProtKB=X2JAX8 X2JAX8 Nost PTHR23065:SF7 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 NOSTRIN, ISOFORM H membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0024289|UniProtKB=O97479 O97479 Sord1 PTHR43161:SF29 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;alcohol metabolic process#GO:0006066;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;hexose biosynthetic process#GO:0019319;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate catabolic process#GO:0016052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0038849|UniProtKB=Q9VDF7 Q9VDF7 Dmel\CG7079 PTHR11008:SF32 PROTEIN TAKEOUT-LIKE PROTEIN GH08336P-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0021796|UniProtKB=Q9VK45 Q9VK45 mTor PTHR11139:SF134 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE MTOR kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;TORC2 signaling#GO:0038203;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;negative regulation of catabolic process#GO:0009895;TORC1 signaling#GO:0038202;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of macroautophagy#GO:0016242;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;TOR signaling#GO:0031929;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of macroautophagy#GO:0016241 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;TOR complex#GO:0038201;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>mTOR#P04638;PDGF signaling pathway#P00047>mTOR#P01144;Interleukin signaling pathway#P00036>mTOR#P00966;Hypoxia response via HIF activation#P00030>TOR#P00817 DROME|FlyBase=FBgn0033538|UniProtKB=A8DY95 A8DY95 Dmel\CG11883 PTHR11575:SF48 5'-NUCLEOTIDASE-RELATED ECTO-5'-NUCLEOTIDASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 DROME|FlyBase=FBgn0034971|UniProtKB=A0A0B4LGJ9 A0A0B4LGJ9 Gpat4 PTHR23063:SF2 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4, ISOFORM D-RELATED intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0020445|UniProtKB=Q7KU30 Q7KU30 E23 PTHR48041:SF63 ABC TRANSPORTER G FAMILY MEMBER 28 EARLY GENE AT 23, ISOFORM C transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0085395|UniProtKB=A8DYR5 A8DYR5 Shawl PTHR11537:SF278 VOLTAGE-GATED POTASSIUM CHANNEL SHAW-LIKE, ISOFORM C voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 action potential#GO:0001508;metal ion transport#GO:0030001;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;postsynapse#GO:0098794;cell body#GO:0044297;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054;cell leading edge#GO:0031252;presynapse#GO:0098793;neuron projection#GO:0043005;protein-containing complex#GO:0032991;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;axon terminus#GO:0043679;membrane#GO:0016020;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886 ion channel#PC00133;voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0033426|UniProtKB=A1Z7V9 A1Z7V9 Nt5c PTHR12103:SF12 5'-NUCLEOTIDASE DOMAIN-CONTAINING FI20020P1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 DROME|FlyBase=FBgn0025827|UniProtKB=A1ZAL1 A1ZAL1 EG:EG0003.8 PTHR11195:SF13 DESTABILASE-RELATED LYSOZYME catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;lysozyme activity#GO:0003796 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0050101|UniProtKB=Q7K0W4 Q7K0W4 Vajk4 PTHR47771:SF15 LD27203P-RELATED LD27203P carbohydrate derivative binding#GO:0097367;binding#GO:0005488 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0261985|UniProtKB=Q9W0R3 Q9W0R3 Ptpmeg PTHR45706:SF4 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 DROME|FlyBase=FBgn0039376|UniProtKB=Q9VBL8 Q9VBL8 Dmel\CG14354 PTHR37161:SF2 HDC10475 AT11648P-RELATED DROME|FlyBase=FBgn0043010|UniProtKB=Q9V6L9 Q9V6L9 Fsn PTHR12245:SF7 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN F-BOX_SPRY DOMAIN-CONTAINING PROTEIN 1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cell junction assembly#GO:0034329;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;cell junction organization#GO:0034330;synapse assembly#GO:0007416;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cell junction#GO:0030054;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0022985|UniProtKB=Q9W254 Q9W254 qkr58E-2 PTHR11208:SF140 RNA-BINDING PROTEIN RELATED GH05812P-RELATED mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0052230|UniProtKB=Q8SYJ2 Q8SYJ2 ND-MLRQ PTHR14256:SF1 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT GEO09626P1 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0052598|UniProtKB=Q8IR50 Q8IR50 betaNACtes6 PTHR10351:SF23 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0021944|UniProtKB=Q9V3D2 Q9V3D2 Coprox PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;porphyrin-containing compound biosynthetic process#GO:0006779;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxidase#PC00175 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 DROME|FlyBase=FBgn0004584|UniProtKB=P27864 P27864 Rrp1 PTHR22748:SF6 AP ENDONUCLEASE DNA REPAIR NUCLEASE_REDOX REGULATOR APEX1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;endonuclease activity#GO:0004519;exonuclease activity#GO:0004527;DNA endonuclease activity#GO:0004520;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408 base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170 DROME|FlyBase=FBgn0033268|UniProtKB=Q7K084 Q7K084 Obp44a PTHR11857:SF46 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 99A-RELATED system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0037535|UniProtKB=Q9VHX6 Q9VHX6 PIG-H PTHR15231:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;biosynthetic process#GO:0009058;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;metabolic process#GO:0008152 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0030694|UniProtKB=Q4QQ70 Q4QQ70 Dmel\CG15602 PTHR46603:SF1 ABSCISSION/NOCUT CHECKPOINT REGULATOR ABSCISSION_NOCUT CHECKPOINT REGULATOR phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075 cellular anatomical structure#GO:0110165;organelle#GO:0043226;midbody#GO:0030496;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cell division site#GO:0032153;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cleavage furrow#GO:0032154;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 DROME|FlyBase=FBgn0029877|UniProtKB=Q9W3Y8 Q9W3Y8 BcDNA:AT19932 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0265607|UniProtKB=M9MRJ2 M9MRJ2 beat-IIIa PTHR21261:SF19 BEAT PROTEIN BEATEN PATH IIIA, ISOFORM D-RELATED cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0036895|UniProtKB=Q9VW23 Q9VW23 ms(3)76Cc PTHR40552:SF6 AT05186P-RELATED FI09606P-RELATED DROME|FlyBase=FBgn0037731|UniProtKB=Q9I7K4 Q9I7K4 Dmel\CG18542 PTHR13947:SF37 GNAT FAMILY N-ACETYLTRANSFERASE LD18367P N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038 DROME|FlyBase=FBgn0033774|UniProtKB=Q7JYV3 Q7JYV3 anon-WO0140519.63 PTHR11705:SF123 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 DOMAIN-CONTAINING PROTEIN-RELATED metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0003373|UniProtKB=P02840 P02840 Sgs3 PTHR21523:SF14 FAMILY NOT NAMED SALIVARY GLUE PROTEIN SGS-3 DROME|FlyBase=FBgn0052081|UniProtKB=Q8IQF3 Q8IQF3 FBgn 52081 PTHR22950:SF340 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0259176|UniProtKB=Q24523 Q24523 bun PTHR46745:SF1 TSC22 DOMAIN FAMILY PROTEIN 1 TSC22 DOMAIN FAMILY PROTEIN 1 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;regulation of cell population proliferation#GO:0042127;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 DROME|FlyBase=FBgn0002022|UniProtKB=Q9V3A4 Q9V3A4 Catsup PTHR16950:SF25 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER SLC39A7 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 DROME|Gene_ORFName=Dmel_CG46513|UniProtKB=A0ACD4DAW8 A0ACD4DAW8 CG46513 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular component assembly#GO:0022607;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0261401|UniProtKB=Q9VVL2 Q9VVL2 Ir75c PTHR42643:SF32 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 31A, ISOFORM C-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0010433|UniProtKB=P48987 P48987 ato PTHR19290:SF169 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED PROTEIN ATONAL RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell fate commitment#GO:0045165;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0033065|UniProtKB=Q9V9L1 Q9V9L1 Cyp6w1 PTHR24292:SF45 CYTOCHROME P450 CYTOCHROME P450 6G1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0003716|UniProtKB=Q9VMT1 Q9VMT1 tkv PTHR23255:SF106 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089;kinase activity#GO:0016301;activin binding#GO:0048185;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773 multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;activin receptor signaling pathway#GO:0032924 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;GBB signaling pathway#P06214>TKV#P06300;DPP signaling pathway#P06213>TKV#P06286;DPP-SCW signaling pathway#P06212>TKV#P06267 DROME|FlyBase=FBgn0014133|UniProtKB=M9PHA0 M9PHA0 bif PTHR13289:SF3 PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL BIFOCAL, ISOFORM F protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 chemotaxis#GO:0006935;response to external stimulus#GO:0009605;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;locomotion#GO:0040011;response to stimulus#GO:0050896;taxis#GO:0042330;response to chemical#GO:0042221;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;rough endoplasmic reticulum#GO:0005791;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane#GO:0016020;nucleus#GO:0005634;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;nuclear membrane#GO:0031965;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 transporter#PC00227 DROME|FlyBase=FBgn0010411|UniProtKB=P41094 P41094 RpS18 PTHR10871:SF3 30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN US13 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosol#GO:0005829;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 DROME|FlyBase=FBgn0037940|UniProtKB=Q9VGJ1 Q9VGJ1 Dmel\CG14720 PTHR21398:SF21 AGAP007094-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0038775|UniProtKB=Q9VDP6 Q9VDP6 Dmel\CG17199 PTHR11091:SF0 OXIDOREDUCTASE-RELATED MALATE DEHYDROGENASE oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Allantoin degradation#P02725>Ureidoglycolate dehydrogenase#P02820;TCA cycle#P00051>Malate Dehydrogenase#P01270;Pyruvate metabolism#P02772>Malate Dehydrogenase#P03138 DROME|FlyBase=FBgn0052699|UniProtKB=Q0KHU5 Q0KHU5 LPCAT PTHR23063:SF63 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034990|UniProtKB=Q59E63 Q59E63 Dmel\CG11406 PTHR11005:SF156 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121;lipase#PC00143 DROME|FlyBase=FBgn0030554|UniProtKB=Q9VY45 Q9VY45 Dus2 PTHR45936:SF1 TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0024992|UniProtKB=Q9W4W8 Q9W4W8 Spg7 PTHR43655:SF8 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT PARAPLEGIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0030563|UniProtKB=Q9VY38 Q9VY38 betaNACtes2 PTHR10351:SF23 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0085422|UniProtKB=Q9VQM8 Q9VQM8 Dmel\CG34393 PTHR23113:SF349 GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBFAMILY NOT NAMED guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0005683|UniProtKB=Q9VKW2 Q9VKW2 pie PTHR12420:SF50 PHD FINGER PROTEIN LD43541P-RELATED intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0035714|UniProtKB=Q9VRY5 Q9VRY5 Sbds PTHR10927:SF1 RIBOSOME MATURATION PROTEIN SBDS RIBOSOME MATURATION PROTEIN SBDS RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035231|UniProtKB=Q9W0D9 Q9W0D9 Pcyt2 PTHR10739:SF13 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE cation binding#GO:0043169;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylcholine binding#GO:0031210;catalytic activity#GO:0003824;transferase activity#GO:0016740;phospholipid binding#GO:0005543;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 transferase#PC00220 DROME|FlyBase=FBgn0040376|UniProtKB=Q9W4Y1 Q9W4Y1 AANATL7 PTHR20905:SF32 N-ACETYLTRANSFERASE-RELATED ARALKYLAMINE N-ACETYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0037153|UniProtKB=Q6NP60 Q6NP60 olf413 PTHR10157:SF40 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 hydroxylase#PC00122 DROME|FlyBase=FBgn0020909|UniProtKB=P56175 P56175 Rtc1 PTHR11096:SF1 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;cyclase activity#GO:0009975;nuclease activity#GO:0004518 cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035431|UniProtKB=Q9VZR5 Q9VZR5 anon-WO0107627.3 PTHR11232:SF57 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER RE46159P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0286508|UniProtKB=Q9VXI1 Q9VXI1 Had1 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0040077|UniProtKB=P82890 P82890 primo-1 PTHR11717:SF7 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195 DROME|FlyBase=FBgn0266111|UniProtKB=A1Z8X3 A1Z8X3 ana3 PTHR31691:SF1 ROTATIN ROTATIN cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell projection organization#GO:0030030;centriole replication#GO:0007099;organelle assembly#GO:0070925;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;centriole#GO:0005814;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0032613|UniProtKB=Q9VJH0 Q9VJH0 Nepl9 PTHR11733:SF222 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED IP12942P hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0032520|UniProtKB=Q9VJY4 Q9VJY4 Dmel\CG10859 PTHR12442:SF7 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;organelle assembly#GO:0070925;cilium movement#GO:0003341;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;outer dynein arm#GO:0036157;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0051860|UniProtKB=Q9VKA3 Q9VKA3 ZnT33D PTHR11562:SF105 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER RE54080P-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 metal ion transport#GO:0030001;response to stimulus#GO:0050896;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;response to chemical#GO:0042221;transport#GO:0006810;response to metal ion#GO:0010038;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0029152|UniProtKB=Q9VP20 Q9VP20 Mkrn1 PTHR11224:SF10 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030886|UniProtKB=Q9VWZ8 Q9VWZ8 Dmel\CG12672 PTHR33995:SF7 PROTEIN CBG18546 CPW-WPC DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0030310|UniProtKB=Q9VYX7 Q9VYX7 PGRP-SA PTHR11022:SF74 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN SA signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783 defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0034299|UniProtKB=A1ZB29 A1ZB29 Dtymk PTHR10344:SF9 THYMIDYLATE KINASE THYMIDYLATE KINASE catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleoside diphosphate metabolic process#GO:0009132;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220;nucleotide kinase#PC00172;kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 DROME|FlyBase=FBgn0035942|UniProtKB=Q9VSR7 Q9VSR7 ValRS-m PTHR11946:SF93 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0032929|UniProtKB=Q9VIE6 Q9VIE6 Mcm10 PTHR13454:SF11 PROTEIN MCM10 HOMOLOG PROTEIN MCM10 HOMOLOG single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0030391|UniProtKB=Q8IR80 Q8IR80 Rab40 PTHR47980:SF21 LD44762P RE54550P ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;export from cell#GO:0140352;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;proteasomal protein catabolic process#GO:0010498 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020 DROME|FlyBase=FBgn0286784|UniProtKB=Q7KN62 Q7KN62 TER94 PTHR23077:SF202 AAA-FAMILY ATPASE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE TER94 protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;modification-dependent protein binding#GO:0140030;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;polyubiquitin modification-dependent protein binding#GO:0031593;hydrolase activity, acting on acid anhydrides#GO:0016817 response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;autophagosome maturation#GO:0097352;transport#GO:0006810;establishment of localization#GO:0051234;spindle organization#GO:0007051;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;protein-containing complex disassembly#GO:0032984;response to endoplasmic reticulum stress#GO:0034976;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;ERAD pathway#GO:0036503 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0037378|UniProtKB=Q9VNI4 Q9VNI4 PSMG1 PTHR15069:SF1 PROTEASOME ASSEMBLY CHAPERONE 1 PROTEASOME ASSEMBLY CHAPERONE 1 protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;chaperone-mediated protein complex assembly#GO:0051131;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;protein folding chaperone complex#GO:0101031;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|FlyBase=FBgn0039681|UniProtKB=Q9VAJ0 Q9VAJ0 Dmel\CG7582 PTHR31885:SF6 GH04784P LYSOPLASMALOGENASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0034406|UniProtKB=Q7K1W4 Q7K1W4 Jheh3 PTHR21661:SF35 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152 hydrolase#PC00121 DROME|FlyBase=FBgn0053287|UniProtKB=B7Z095 B7Z095 CG12982 PTHR20929:SF12 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED AT08232P protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0034534|UniProtKB=A0A0B4LH09 A0A0B4LH09 maf-S PTHR10129:SF48 TRANSCRIPTION FACTOR MAF MAF-S, ISOFORM B cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0265605|UniProtKB=Q7JMZ0 Q7JMZ0 Ric PTHR24070:SF266 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 DROME|FlyBase=FBgn0039198|UniProtKB=A0A6H2EF03 A0A6H2EF03 Dmel\CG5768 PTHR21398:SF7 AGAP007094-PA LP19941P DROME|FlyBase=FBgn0005614|UniProtKB=P48994 P48994 trpl PTHR10117:SF47 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT-RECEPTOR-POTENTIAL-LIKE PROTEIN transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;channel activity#GO:0015267;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;binding#GO:0005488;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;metal ion transport#GO:0030001;homeostatic process#GO:0042592 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 DROME|FlyBase=FBgn0024814|UniProtKB=Q9VWA1 Q9VWA1 Clc PTHR10639:SF46 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN protein binding#GO:0005515;binding#GO:0005488;clathrin binding#GO:0030276 clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;coated vesicle#GO:0030135;coated membrane#GO:0048475;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;clathrin vesicle coat#GO:0030125;cytoplasm#GO:0005737;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;presynapse#GO:0098793;secretory vesicle#GO:0099503 membrane traffic protein#PC00150;vesicle coat protein#PC00235 Huntington disease#P00029>Clathrin#P00798;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 DROME|FlyBase=FBgn0004919|UniProtKB=Q06003 Q06003 gol PTHR22765:SF405 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE GOLIATH catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0054045|UniProtKB=A1ZBJ7 A1ZBJ7 BP1009 PTHR16983:SF10 UPAR/LY6 DOMAIN-CONTAINING PROTEIN PROTEIN QUIVER protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0083992|UniProtKB=Q9NGL1 Q9NGL1 Mkp PTHR46377:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of biological process#GO:0050789;regulation of JNK cascade#GO:0046328;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 DROME|FlyBase=FBgn0265512|UniProtKB=Q7K549 Q7K549 mlt PTHR15140:SF69 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE COFACTOR E-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0034962|UniProtKB=Q7JRE4 Q7JRE4 MAN1 PTHR13428:SF12 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN INNER NUCLEAR MEMBRANE PROTEIN MAN1 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 nuclear envelope organization#GO:0006998;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;membrane assembly#GO:0071709;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 DROME|FlyBase=FBgn0034275|UniProtKB=Q7K4I4 Q7K4I4 neat PTHR11814:SF132 SULFATE TRANSPORTER LD38576P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0023170|UniProtKB=O16130 O16130 RpL39 PTHR19970:SF0 RIBOSOMAL PROTEIN L39E LARGE RIBOSOMAL SUBUNIT PROTEIN EL39 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625 ribosomal protein#PC00202 DROME|FlyBase=FBgn0023537|UniProtKB=Q7KW39 Q7KW39 CG17896 PTHR43866:SF3 MALONATE-SEMIALDEHYDE DEHYDROGENASE METHYLMALONATE-SEMIALDEHYDE_MALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carboxylic acid catabolic process#GO:0046395;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;nucleobase catabolic process#GO:0046113;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;pyrimidine nucleobase catabolic process#GO:0006208 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Methylmalonate Semialdehyde Dehydrogenase#P03124 DROME|FlyBase=FBgn0030638|UniProtKB=Q9VXV4 Q9VXV4 Dmel\CG11655 PTHR10361:SF70 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 primary active transporter#PC00068 DROME|FlyBase=FBgn0037555|UniProtKB=Q8I8V0 Q8I8V0 Ada2b PTHR12374:SF63 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-BETA binding#GO:0005488;transcription coregulator activity#GO:0003712;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0023212|UniProtKB=O44226 O44226 EloB PTHR13248:SF4 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2 ELONGIN-B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;post-transcriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;modification-dependent protein catabolic process#GO:0019941;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;protein catabolic process#GO:0030163;negative regulation of metabolic process#GO:0009892;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular organelle lumen#GO:0070013;Cul2-RING ubiquitin ligase complex#GO:0031462;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 DROME|FlyBase=FBgn0042185|UniProtKB=Q8IQ70 Q8IQ70 MCU PTHR13462:SF10 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL passive transmembrane transporter activity#GO:0022803;secondary active transmembrane transporter activity#GO:0015291;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;transporter complex#GO:1990351;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 DROME|FlyBase=FBgn0039864|UniProtKB=Q9V9V4 Q9V9V4 Dmel\CG11550 PTHR10174:SF213 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0011710|UniProtKB=P42207 P42207 Septin1 PTHR18884:SF136 SEPTIN SEPTIN-1 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;macromolecule localization#GO:0033036;cell cycle#GO:0007049 cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 DROME|FlyBase=FBgn0040251|UniProtKB=Q9VGT5 Q9VGT5 Ugt302K1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0033408|UniProtKB=A1Z7U2 A1Z7U2 ODA-Dnal1 PTHR15454:SF73 NISCHARIN RELATED DYNEIN AXONEMAL LIGHT CHAIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 organelle assembly#GO:0070925;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0010300|UniProtKB=Q8MQJ9 Q8MQJ9 brat PTHR24104:SF41 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED PROTEIN BRAIN TUMOR acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;translation regulator activity#GO:0045182 protein modification by small protein conjugation or removal#GO:0070647;negative regulation of translation#GO:0017148;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030975|UniProtKB=Q9VWN3 Q9VWN3 SdhBL PTHR11921:SF47 SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0053236|UniProtKB=Q7KV12 Q7KV12 Ste:CG33236 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0278608|UniProtKB=Q24537 Q24537 Dsp1 PTHR48112:SF44 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN DSP1 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 DROME|FlyBase=FBgn0001223|UniProtKB=P02515 P02515 Hsp22 PTHR45640:SF40 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN 22-RELATED protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chaperone#PC00072 DROME|FlyBase=FBgn0283531|UniProtKB=Q9VQH2 Q9VQH2 Duox PTHR11972:SF175 NADPH OXIDASE DUAL OXIDASE oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824 response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896;defense response#GO:0006952 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;catalytic complex#GO:1902494 oxidase#PC00175;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0030437|UniProtKB=Q9VYH9 Q9VYH9 hec PTHR45620:SF43 PDF RECEPTOR-LIKE PROTEIN-RELATED HECTOR, ISOFORM A G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0011818|UniProtKB=Q9NLA6 Q9NLA6 oaf PTHR13423:SF2 OUT AT FIRST OUT AT FIRST PROTEIN HOMOLOG DROME|FlyBase=FBgn0031042|UniProtKB=M9PHK6 M9PHK6 Dmel\CG14221 PTHR46135:SF3 NME/NM23 FAMILY MEMBER 8 NME_NM23 FAMILY MEMBER 8 DROME|FlyBase=FBgn0010340|UniProtKB=P81928 P81928 Timmdc1 PTHR13002:SF1 C3ORF1 PROTEIN-RELATED COMPLEX I ASSEMBLY FACTOR TIMMDC1, MITOCHONDRIAL intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0029971|UniProtKB=Q9W3N7 Q9W3N7 ND-MNLL PTHR15222:SF2 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0020251|UniProtKB=Q9V3L1 Q9V3L1 sfl PTHR10605:SF77 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE deacetylase activity#GO:0019213;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;deacylase activity#GO:0160215;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0264907|UniProtKB=D2NUL5 D2NUL5 CG31530-RA PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0040250|UniProtKB=Q9VGS8 Q9VGS8 Ugt304A1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0015583|UniProtKB=O46197 O46197 Acp29AB PTHR22803:SF124 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED ACCESSORY GLAND PROTEIN ACP29AB-RELATED membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0039022|UniProtKB=Q9VCU3 Q9VCU3 Nepl13 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0034162|UniProtKB=Q7JYZ0 Q7JYZ0 l(2)k04810 PTHR11195:SF13 DESTABILASE-RELATED LYSOZYME catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;lysozyme activity#GO:0003796 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0243511|UniProtKB=Q9VDQ7 Q9VDQ7 psidin PTHR22767:SF3 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234 acetyltransferase#PC00038 DROME|FlyBase=FBgn0034365|UniProtKB=A1ZBB1 A1ZBB1 ctg PTHR11346:SF191 GALECTIN GALECTIN carbohydrate binding#GO:0030246;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0004778|UniProtKB=O97063 O97063 Ccp84Af PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0039650|UniProtKB=Q9VAM9 Q9VAM9 Mesh1 PTHR46246:SF1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 hydrolase#PC00121 DROME|FlyBase=FBgn0051374|UniProtKB=Q9VGN4 Q9VGN4 sals PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED ACTIN NUCLEATION-PROMOTING FACTOR WAS-RELATED binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0002921|UniProtKB=P13607 P13607 Atpalpha PTHR43294:SF13 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;potassium ion homeostasis#GO:0055075;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;homeostatic process#GO:0042592;export from cell#GO:0140352;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0038755|UniProtKB=Q9VDR6 Q9VDR6 Hs6st PTHR12812:SF0 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 transferase#PC00220 DROME|FlyBase=FBgn0033067|UniProtKB=Q7JWF7 Q7JWF7 Dmel\CG11211 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0052206|UniProtKB=R9PY60 R9PY60 CG14091 PTHR47537:SF8 CUBILIN CUB DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0035287|UniProtKB=Q8IRG5 Q8IRG5 d4ST2 PTHR12137:SF63 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220 DROME|FlyBase=FBgn0002633|UniProtKB=P13097 P13097 E(spl)m7-HLH PTHR10985:SF12 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED ENHANCER OF SPLIT M3 PROTEIN-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of neurogenesis#GO:0050767;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;pattern specification process#GO:0007389;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 DROME|FlyBase=FBgn0030479|UniProtKB=M9MS48 M9MS48 Rbp1-like PTHR23147:SF75 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 1-RELATED membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear speck#GO:0016607;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0036612|UniProtKB=Q0E8E2 Q0E8E2 SPH66 PTHR24258:SF142 SERINE PROTEASE-RELATED PHENOLOXIDASE-ACTIVATING FACTOR 2 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034490|UniProtKB=Q494G1 Q494G1 Dmel\CG9864 PTHR11662:SF336 SOLUTE CARRIER FAMILY 17 LP19554P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0002121|UniProtKB=P08111 P08111 l(2)gl PTHR10241:SF29 LETHAL 2 GIANT LARVAE PROTEIN LETHAL(2) GIANT LARVAE PROTEIN protein binding#GO:0005515;enzyme regulator activity#GO:0030234;syntaxin binding#GO:0019905;molecular function activator activity#GO:0140677;binding#GO:0005488;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;SNARE binding#GO:0000149;enzyme activator activity#GO:0008047;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 establishment of spindle localization#GO:0051293;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;transport#GO:0006810;regulation of response to stimulus#GO:0048583;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;cell cycle#GO:0007049;establishment of cell polarity#GO:0030010;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;Golgi to plasma membrane transport#GO:0006893;regulation of cell communication#GO:0010646;cortical cytoskeleton organization#GO:0030865;organelle localization#GO:0051640;regulation of Notch signaling pathway#GO:0008593;actin filament-based process#GO:0030029;localization within membrane#GO:0051668;microtubule cytoskeleton organization#GO:0000226;secretion#GO:0046903;cortical actin cytoskeleton organization#GO:0030866;localization#GO:0051179;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of establishment or maintenance of cell polarity#GO:0032878;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;exocytosis#GO:0006887;cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;establishment or maintenance of cell polarity#GO:0007163;regulation of signaling#GO:0023051;spindle localization#GO:0051653;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0035065|UniProtKB=Q9W106 Q9W106 Dmel\CG3589 PTHR21004:SF0 SERINE PROTEASE-RELATED PEROXISOMAL LEADER PEPTIDE-PROCESSING PROTEASE hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;proteolysis#GO:0006508;regulation of lipid metabolic process#GO:0019216;protein metabolic process#GO:0019538;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 serine protease#PC00203 DROME|FlyBase=FBgn0051636|UniProtKB=Q8IPJ5 Q8IPJ5 CG13770 PTHR10174:SF216 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN-RELATED small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0027562|UniProtKB=Q9VET1 Q9VET1 BcDNA:GH08773 PTHR11923:SF104 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI07620P cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0020639|UniProtKB=P92194 P92194 Lcp65Af PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0012051|UniProtKB=Q11002 Q11002 CalpA PTHR10183:SF379 CALPAIN CALPAIN-A-RELATED protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 DROME|FlyBase=FBgn0000075|UniProtKB=P18486 P18486 amd PTHR11999:SF60 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE 3,4-DIHYDROXYPHENYLACETALDEHYDE SYNTHASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 catecholamine metabolic process#GO:0006584;serotonin metabolic process#GO:0042428;metabolic process#GO:0008152;serotonin biosynthetic process#GO:0042427;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;amine metabolic process#GO:0009308;phenol-containing compound biosynthetic process#GO:0046189;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;phenol-containing compound metabolic process#GO:0018958 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;decarboxylase#PC00089 5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400 DROME|FlyBase=FBgn0035977|UniProtKB=Q8SXQ7 Q8SXQ7 PGRP-LF PTHR11022:SF80 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;peptidoglycan muralytic activity#GO:0061783;signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0000053|UniProtKB=P00967 P00967 Gart PTHR10520:SF12 TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleobase metabolic process#GO:0006144;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908 DROME|FlyBase=FBgn0030519|UniProtKB=Q9VY92 Q9VY92 Dmel\CG11151 PTHR10094:SF25 STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN SCP2 STEROL-BINDING DOMAIN-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0284442|UniProtKB=Q9XYU1 Q9XYU1 Mcm3 PTHR11630:SF46 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;MCM complex#GO:0042555;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0036259|UniProtKB=M9PFD5 M9PFD5 Dmel\CG9760 PTHR39074:SF1 AGAP007547-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0031592|UniProtKB=Q9VQX9 Q9VQX9 Art2 PTHR11006:SF124 PROTEIN ARGININE N-METHYLTRANSFERASE ARGININE METHYLTRANSFERASE 9-RELATED histone modifying activity#GO:0140993;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036005|UniProtKB=Q9VT01 Q9VT01 pall PTHR13252:SF9 F-BOX ONLY PROTEIN 28 F-BOX ONLY PROTEIN 28 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 DROME|FlyBase=FBgn0024288|UniProtKB=Q9VA17 Q9VA17 Sox100B PTHR45803:SF5 SOX100B SOX100B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0017579|UniProtKB=P55841 P55841 RpL14 PTHR11127:SF2 60S RIBOSOMAL PROTEIN L14 LARGE RIBOSOMAL SUBUNIT PROTEIN EL14 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 DROME|FlyBase=FBgn0034914|UniProtKB=A0A0B4LHC9 A0A0B4LHC9 Dmel\CG5554 PTHR46107:SF3 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0029665|UniProtKB=Q9W4R8 Q9W4R8 Timm29 PTHR21435:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 mitochondrial transport#GO:0006839;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;protein insertion into mitochondrial inner membrane#GO:0045039;membrane organization#GO:0061024;mitochondrial protein import pathway#GO:7770058;mitochondrion organization#GO:0007005;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907 mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0044328|UniProtKB=Q8IQD3 Q8IQD3 Dmel\CG32052 PTHR10340:SF63 SPHINGOMYELIN PHOSPHODIESTERASE METALLOPHOS DOMAIN-CONTAINING PROTEIN phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;hydrolase#PC00121 DROME|FlyBase=FBgn0034242|UniProtKB=Q7JWU9 Q7JWU9 Dmel\CG14480 PTHR13495:SF0 NEFA-INTERACTING NUCLEAR PROTEIN NIP30 PSME3-INTERACTING PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038471|UniProtKB=Q9VEP1 Q9VEP1 Trm7-32 PTHR10920:SF12 RIBOSOMAL RNA METHYLTRANSFERASE TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0039669|UniProtKB=Q9VAK5 Q9VAK5 ND-20L PTHR11995:SF14 NADH DEHYDROGENASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;electron transfer activity#GO:0009055;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;energy derivation by oxidation of organic compounds#GO:0015980;transmembrane transport#GO:0055085;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;monoatomic ion transport#GO:0006811;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0027070|UniProtKB=Q9VJ45 Q9VJ45 Ugt36E1 PTHR48043:SF114 EG:EG0003.4 PROTEIN-RELATED IP04436P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0038153|UniProtKB=Q9VFV0 Q9VFV0 Ir87a PTHR42643:SF43 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 60A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036691|UniProtKB=Q8T3L6 Q8T3L6 beg PTHR42681:SF8 MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0024187|UniProtKB=Q9GQF1 Q9GQF1 syd PTHR13886:SF4 JNK/SAPK-ASSOCIATED PROTEIN JNK-INTERACTING PROTEIN 3 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;protein complex scaffold activity#GO:0140378;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;structural molecule activity#GO:0005198;MAP kinase scaffold activity#GO:0005078 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037623|UniProtKB=Q0KIA2 Q0KIA2 CG9801 PTHR21586:SF0 TIPA PP2C-LIKE DOMAIN-CONTAINING PROTEIN CG9801 DROME|FlyBase=FBgn0032474|UniProtKB=M9PD23 M9PD23 DnaJ-H PTHR43888:SF31 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 2 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;protein refolding#GO:0042026;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 DROME|FlyBase=FBgn0022709|UniProtKB=Q8IQG9 Q8IQG9 Ak1 PTHR23359:SF70 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 1 phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 DROME|FlyBase=FBgn0038980|UniProtKB=Q9VCZ3 Q9VCZ3 Octbeta1R PTHR24248:SF134 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OCTOPAMINE RECEPTOR BETA-1R G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 DROME|FlyBase=FBgn0031119|UniProtKB=Q9VRA7 Q9VRA7 Dmel\CG1812 PTHR45632:SF3 LD33804P KELCH-LIKE PROTEIN DIABLO ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038649|UniProtKB=Q8SYL0 Q8SYL0 PGS1 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220 DROME|FlyBase=FBgn0026077|UniProtKB=Q9VNL0 Q9VNL0 Gasp PTHR23301:SF100 CHITIN BINDING PERITROPHIN-A GASP, ISOFORM A binding#GO:0005488;carbohydrate derivative binding#GO:0097367 external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0267796|UniProtKB=A0A0U1QT59 A0A0U1QT59 Tmc PTHR23302:SF40 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 DROME|FlyBase=FBgn0053680|UniProtKB=Q4ABK2 Q4ABK2 Jhbp10 PTHR11008:SF39 PROTEIN TAKEOUT-LIKE PROTEIN JUVENILE HORMONE BINDING PROTEIN 10 rhythmic process#GO:0048511;circadian rhythm#GO:0007623 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0051694|UniProtKB=Q9VQI5 Q9VQI5 Ifrd1 PTHR12354:SF1 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1 DROME|FlyBase=FBgn0025725|UniProtKB=Q9W0B8 Q9W0B8 alphaCOP PTHR19876:SF1 COATOMER COATOMER SUBUNIT ALPHA retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 membrane coat#GO:0030117;coated membrane#GO:0048475;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0038901|UniProtKB=Q9VD83 Q9VD83 Burs PTHR15283:SF7 GREMLIN 1 BURSICON molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine binding#GO:0019955;neuropeptide hormone activity#GO:0005184;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;binding#GO:0005488 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0035542|UniProtKB=M9NFM7 M9NFM7 TP53INP PTHR31671:SF3 DIABETES AND OBESITY REGULATED, ISOFORM G DIABETES AND OBESITY REGULATED, ISOFORM G transcription regulator activity#GO:0140110;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;transcription coregulator activity#GO:0003712;protein-membrane adaptor activity#GO:0043495;transcription coactivator activity#GO:0003713 positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;process utilizing autophagic mechanism#GO:0061919;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;macroautophagy#GO:0016236;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;vacuole organization#GO:0007033;regulation of RNA metabolic process#GO:0051252;organelle assembly#GO:0070925 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;autophagosome#GO:0005776;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DROME|FlyBase=FBgn0052767|UniProtKB=Q9W4E8 Q9W4E8 i7 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0003520|UniProtKB=P25159 P25159 stau PTHR46054:SF3 MATERNAL EFFECT PROTEIN STAUFEN MATERNAL EFFECT PROTEIN STAUFEN RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725 protein localization to cell junction#GO:1902414;microtubule-based transport#GO:0099111;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule-based movement#GO:0007018;gamete generation#GO:0007276;RNA localization#GO:0006403;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;intracellular transport#GO:0046907;transport#GO:0006810;developmental process#GO:0032502;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;protein localization to synapse#GO:0035418;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;axo-dendritic transport#GO:0008088;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705 cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 DROME|FlyBase=FBgn0032305|UniProtKB=Q9VKP5 Q9VKP5 Dmel\CG6700 PTHR12436:SF4 80 KDA MCM3-ASSOCIATED PROTEIN LEUKOCYTE RECEPTOR CLUSTER MEMBER 8 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0041723|UniProtKB=Q76NQ1 Q76NQ1 rho-5 PTHR45965:SF3 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 1 regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of secretion#GO:0051046;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of response to stimulus#GO:0048583;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 serine protease#PC00203 DROME|FlyBase=FBgn0032790|UniProtKB=Q9VIV6 Q9VIV6 Dmel\CG10194 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 ACYL-COENZYME A DIPHOSPHATASE NUDT19 DROME|FlyBase=FBgn0031489|UniProtKB=Q0E8U4 Q0E8U4 Dmel\CG17224 PTHR43691:SF11 URIDINE PHOSPHORYLASE FI09636P-RELATED cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 DROME|FlyBase=FBgn0038569|UniProtKB=Q9VED0 Q9VED0 CG7218 PTHR13317:SF5 TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;positive regulation of biological process#GO:0048518;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cell projection assembly#GO:0060491;positive regulation of organelle organization#GO:0010638;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130 membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;ciliary basal body#GO:0036064;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;cilium#GO:0005929;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 DROME|FlyBase=FBgn0030802|UniProtKB=Q9VX98 Q9VX98 DENR PTHR12789:SF0 DENSITY-REGULATED PROTEIN HOMOLOG DENSITY-REGULATED PROTEIN protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 DROME|FlyBase=FBgn0267351|UniProtKB=Q9V8P9 Q9V8P9 Topors PTHR46077:SF1 E3 UBIQUITIN-PROTEIN LIGASE TOPORS E3 UBIQUITIN-PROTEIN LIGASE TOPORS ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0028743|UniProtKB=Q8T017 Q8T017 Dhit PTHR10845:SF192 REGULATOR OF G PROTEIN SIGNALING DOUBLE HIT, ISOFORM B enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 DROME|FlyBase=FBgn0037026|UniProtKB=Q9VPB1 Q9VPB1 CG3634 PTHR12745:SF6 SUPPRESSION OF TUMORIGENICITY 7 PROTEIN ST7 HOMOLOG DROME|FlyBase=FBgn0036161|UniProtKB=Q8T4I0 Q8T4I0 Khk2 PTHR43085:SF55 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of glycogen biosynthetic process#GO:0005979;monosaccharide metabolic process#GO:0005996;regulation of carbohydrate metabolic process#GO:0006109;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biological process#GO:0050789;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;regulation of carbohydrate biosynthetic process#GO:0043255;carbohydrate metabolic process#GO:0005975;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 DROME|FlyBase=FBgn0033863|UniProtKB=A1Z9G7 A1Z9G7 Dmel\CG13337 PTHR48514:SF3 FAMILY NOT NAMED TRICHOHYALIN-PLECTIN-HOMOLOGY DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0023549|UniProtKB=Q9W509 Q9W509 Mct1 PTHR11360:SF325 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0038163|UniProtKB=Q9VFT7 Q9VFT7 anon-WO0140519.42 PTHR20875:SF0 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED GH12158P calmodulin-related#PC00061 DROME|FlyBase=FBgn0259989|UniProtKB=E1JHG3 E1JHG3 CG42501 PTHR21179:SF0 SERINE-TYPE ENDOPEPTIDASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 4 protease inhibitor#PC00191 DROME|FlyBase=FBgn0023090|UniProtKB=Q8INT5 Q8INT5 dtr PTHR45973:SF38 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN AXONEMAL ASSEMBLY FACTOR 1 protein-containing complex binding#GO:0044877;binding#GO:0005488 developmental process#GO:0032502;left/right pattern formation#GO:0060972;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;determination of bilateral symmetry#GO:0009855;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;regionalization#GO:0003002;cellular component assembly#GO:0022607;microtubule bundle formation#GO:0001578;pattern specification process#GO:0007389;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;determination of left/right symmetry#GO:0007368;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030 cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0030421|UniProtKB=Q9VYJ4 Q9VYJ4 Agpat1 PTHR10434:SF11 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0046302|UniProtKB=Q9VJ22 Q9VJ22 BEST:GH09876 PTHR21721:SF27 GH09876P-RELATED GH09876P DROME|FlyBase=FBgn0035926|UniProtKB=Q9VSP9 Q9VSP9 Acbp5 PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0052305|UniProtKB=Q8IRF5 Q8IRF5 CG8970 PTHR45627:SF12 ADENYLATE CYCLASE TYPE 1 ADENYLYL CYCLASE X E-RELATED adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0034654|UniProtKB=Q9W2D9 Q9W2D9 eIF3k PTHR13022:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 DROME|FlyBase=FBgn0029980|UniProtKB=Q9W3M6 Q9W3M6 Dhdds PTHR10291:SF51 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 acyltransferase#PC00042 DROME|FlyBase=FBgn0039056|UniProtKB=Q9VCQ6 Q9VCQ6 CenB1A PTHR23180:SF399 CENTAURIN/ARF BLOWN FUSE, ISOFORM A-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0039302|UniProtKB=A0A0B4K7J2 A0A0B4K7J2 Nup358 PTHR23138:SF190 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038665|UniProtKB=A0A0B4K7H3 A0A0B4K7H3 euc PTHR10094:SF32 STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN EUCALYPTUS, ISOFORM B cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0263667|UniProtKB=Q9W1H0 Q9W1H0 Lpt PTHR45888:SF6 HL01030P-RELATED HL01030P-RELATED histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;transcription regulator activity#GO:0140110;protein-lysine N-methyltransferase activity#GO:0016279;transcription coactivator activity#GO:0003713;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;histone H3 methyltransferase activity#GO:0140938;histone H3K4 methyltransferase activity#GO:0042800;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0027091|UniProtKB=Q7KN90 Q7KN90 CysRS PTHR10890:SF33 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0028697|UniProtKB=O17445 O17445 RpL15 PTHR11847:SF4 RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN EL15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0034807|UniProtKB=Q9W1W5 Q9W1W5 SPH195 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0040588|UniProtKB=Q9VCU0 Q9VCU0 Dmel\CG13841 PTHR10380:SF192 CUTICLE PROTEIN CUTICULAR PROTEIN 65AU, ISOFORM A-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0264078|UniProtKB=O61492 O61492 Flo2 PTHR13806:SF46 FLOTILLIN-RELATED FLOTILLIN-2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0260243|UniProtKB=Q9VHJ3 Q9VHJ3 E(var)3-9 PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0037094|UniProtKB=Q7K0L4 Q7K0L4 CG7611 PTHR22838:SF28 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 26 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0023023|UniProtKB=Q8IPQ2 Q8IPQ2 CRMP PTHR11647:SF1 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE dihydropyrimidinase activity#GO:0004157;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 DROME|FlyBase=FBgn0004374|UniProtKB=Q9VIP4 Q9VIP4 neb PTHR24115:SF1024 KINESIN-RELATED LP17758P isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987 protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0051926|UniProtKB=Q9VQ13 Q9VQ13 Dmel\CG31926 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 aspartic protease#PC00053;protease#PC00190 DROME|FlyBase=FBgn0031622|UniProtKB=Q9VR20 Q9VR20 CG3251 PTHR12419:SF115 OTU DOMAIN CONTAINING PROTEIN DEUBIQUITINASE OTU-RELATED hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 cysteine protease#PC00081 DROME|FlyBase=FBgn0031309|UniProtKB=Q9VPX4 Q9VPX4 Tfb4 PTHR12831:SF0 TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3 cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170 RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 DROME|FlyBase=FBgn0039373|UniProtKB=Q9VBM1 Q9VBM1 MLC1 PTHR23050:SF552 CALCIUM BINDING PROTEIN AT16150P-RELATED molecular function regulator activity#GO:0098772;cation binding#GO:0043169;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 DROME|FlyBase=FBgn0053288|UniProtKB=Q7KTW3 Q7KTW3 cg33288 PTHR45982:SF1 REGULATOR OF CHROMOSOME CONDENSATION HDC11342-RELATED regulation of mitotic spindle assembly#GO:1901673;regulation of organelle assembly#GO:1902115;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of microtubule-based process#GO:0032886;regulation of spindle assembly#GO:0090169;regulation of mitotic spindle organization#GO:0060236;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0011569|UniProtKB=Q9VT91 Q9VT91 can PTHR19879:SF12 TRANSCRIPTION INITIATION FACTOR TFIID CANNONBALL-RELATED protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367 intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;peptidase complex#GO:1905368;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;acetyltransferase complex#GO:1902493;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123 DROME|FlyBase=FBgn0033246|UniProtKB=A1Z784 A1Z784 Acc PTHR45728:SF9 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE, ISOFORM A ligase activity#GO:0016874;catalytic activity#GO:0003824 monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0286782|UniProtKB=B7YZU2 B7YZU2 flz PTHR24253:SF145 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE FILZIG peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0041237|UniProtKB=Q9W2B2 Q9W2B2 Gr58c PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED cell body#GO:0044297;neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038359|UniProtKB=Q9VF40 Q9VF40 Dmel\CG5614 PTHR15431:SF19 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 20 cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0050088|UniProtKB=A1ZA38 A1ZA38 Dmel\CG30088 PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0032879|UniProtKB=Q9VIK2 Q9VIK2 CarT PTHR24064:SF576 SOLUTE CARRIER FAMILY 22 MEMBER CARCININE TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0261402|UniProtKB=B7Z069 B7Z069 Ir75b PTHR42643:SF32 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 31A, ISOFORM C-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0263490|UniProtKB=A0A0B4K7S6 A0A0B4K7S6 mld PTHR24376:SF216 ZINC FINGER PROTEIN DRACULIN-LIKE 3 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0266084|UniProtKB=E1JI78 E1JI78 Fhos PTHR45920:SF4 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;positive regulation of organelle organization#GO:0010638;supramolecular fiber organization#GO:0097435 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0031390|UniProtKB=E2QCS8 E2QCS8 tho2 PTHR21597:SF0 THO2 PROTEIN THO COMPLEX SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;localization#GO:0051179;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973 transcription export complex#GO:0000346;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 transcription cofactor#PC00217 DROME|FlyBase=FBgn0033705|UniProtKB=A1Z8V5 A1Z8V5 Dmel\CG13168 PTHR31598:SF1 IQ DOMAIN-CONTAINING PROTEIN D DYNEIN REGULATORY COMPLEX SUBUNIT 10 DROME|FlyBase=FBgn0086604|UniProtKB=A8DYJ6 A8DYJ6 side-VIII PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0000121|UniProtKB=P19107 P19107 Arr2 PTHR11792:SF23 ARRESTIN PHOSRESTIN-1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;establishment of localization#GO:0051234;import into cell#GO:0098657;regulation of G protein-coupled receptor signaling pathway#GO:0008277;transport#GO:0006810;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;receptor internalization#GO:0031623;negative regulation of cell communication#GO:0010648;localization#GO:0051179;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>beta-arrestin#P01456 DROME|FlyBase=FBgn0034396|UniProtKB=A0A0B4KEU3 A0A0B4KEU3 Dm.CG15097 PTHR24412:SF505 KELCH PROTEIN BTB DOMAIN-CONTAINING PROTEIN enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0040060|UniProtKB=Q9VRS4 Q9VRS4 yip7 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0264492|UniProtKB=P08181 P08181 CkIIalpha PTHR24054:SF0 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;response to stress#GO:0006950;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0040005|UniProtKB=Q9W5H8 Q9W5H8 Dmel\CG17883 PTHR20913:SF7 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE RE60063P enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0029113|UniProtKB=Q7KUA4 Q7KUA4 Uba2 PTHR10953:SF5 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 2 sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874 protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 DROME|FlyBase=FBgn0030743|UniProtKB=Q9VXH4 Q9VXH4 Dmel\CG9921 PTHR12297:SF18 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 2A mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0027490|UniProtKB=Q9VLL1 Q9VLL1 D12 PTHR23195:SF7 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 2 histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 general transcription factor#PC00259 DROME|FlyBase=FBgn0264490|UniProtKB=A0A0B4KHV1 A0A0B4KHV1 Eip93F PTHR21545:SF13 TRANSCRIPTION FACTOR MLR1/2 ECDYSONE-INDUCED PROTEIN 93F, ISOFORM C regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0031937|UniProtKB=Q9VLY3 Q9VLY3 Dmel\CG13795 PTHR11616:SF337 SODIUM/CHLORIDE DEPENDENT TRANSPORTER BLOATED TUBULES, ISOFORM B-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;glycine transmembrane transporter activity#GO:0015187;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175 establishment of localization#GO:0051234;import into cell#GO:0098657;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;glycine transport#GO:0015816;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 DROME|FlyBase=FBgn0042112|UniProtKB=Q9I7Q9 Q9I7Q9 mRpL36 PTHR46909:SF1 39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL36M cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 DROME|FlyBase=FBgn0036428|UniProtKB=Q9VUF3 Q9VUF3 Gbs-70E PTHR12307:SF36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT protein phosphatase binding#GO:0019903;protein binding#GO:0005515;carbohydrate binding#GO:0030246;enzyme binding#GO:0019899;polysaccharide binding#GO:0030247;phosphatase binding#GO:0019902;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0261881|UniProtKB=Q9V3Y0 Q9V3Y0 Ankrd49 PTHR24189:SF71 MYOTROPHIN ANKYRIN REPEAT DOMAIN 39 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DROME|FlyBase=FBgn0043530|UniProtKB=Q7KE33 Q7KE33 Obp51a PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0037239|UniProtKB=Q9VN13 Q9VN13 Sfxn1-3 PTHR11153:SF8 SIDEROFLEXIN SIDEROFLEXIN-1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;mitochondrial transmembrane transport#GO:1990542;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;intracellular transport#GO:0046907 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 DROME|FlyBase=FBgn0040528|UniProtKB=Q9VHU7 Q9VHU7 CG7553 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;oxidoreductase complex#GO:1990204;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0259227|UniProtKB=Q0KI81 Q0KI81 CG18479 PTHR19134:SF544 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DROME|FlyBase=FBgn0020312|UniProtKB=Q7K4B6 Q7K4B6 Tmtc3 PTHR44395:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC3 DROME|FlyBase=FBgn0039527|UniProtKB=Q9VB21 Q9VB21 Dmel\CG5639 PTHR12352:SF31 SECRETED MODULAR CALCIUM-BINDING PROTEIN PAPILIN-LIKE PROTEIN cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061 DROME|FlyBase=FBgn0039759|UniProtKB=Q9VA87 Q9VA87 c-SP10 PTHR24256:SF527 TRYPTASE-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 Toll pathway-drosophila#P06217>EA#P06339 DROME|FlyBase=FBgn0261277|UniProtKB=Q9VZ21 Q9VZ21 rtv PTHR33562:SF22 ATILLA, ISOFORM B-RELATED-RELATED UPAR_LY6 DOMAIN-CONTAINING PROTEIN RTV DROME|FlyBase=FBgn0015025|UniProtKB=Q9VUU3 Q9VUU3 CkIIalpha-i1 PTHR24384:SF189 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0024945|UniProtKB=O76464 O76464 NitFhit PTHR23088:SF55 NITRILASE-RELATED NITRILASE AND FRAGILE HISTIDINE TRIAD FUSION PROTEIN NITFHIT hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 hydrolase#PC00121 DROME|FlyBase=FBgn0036483|UniProtKB=Q9VUL6 Q9VUL6 Dmel\CG12316 PTHR21656:SF3 MALE-SPECIFIC LETHAL-1 PROTEIN GH22749P histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0015623|UniProtKB=Q27597 Q27597 Cpr PTHR19384:SF17 NITRIC OXIDE SYNTHASE-RELATED NADPH--CYTOCHROME P450 REDUCTASE ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;oxidoreductase activity, acting on NAD(P)H#GO:0016651 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>P450 reductase#P04605 DROME|FlyBase=FBgn0011289|UniProtKB=P52654 P52654 TfIIA-L PTHR12694:SF8 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription coregulator activity#GO:0003712;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 DROME|FlyBase=FBgn0030041|UniProtKB=Q9W3F1 Q9W3F1 144701_at PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 reductase#PC00198 DROME|FlyBase=FBgn0037227|UniProtKB=Q9VMZ8 Q9VMZ8 TwdlV PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0032811|UniProtKB=Q9VIT2 Q9VIT2 Pmvk PTHR13101:SF1 PHOSPHOMEVALONATE KINASE PHOSPHOMEVALONATE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;acyl-CoA metabolic process#GO:0006637;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;nucleoside phosphate metabolic process#GO:0006753;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;acetyl-CoA metabolic process#GO:0006084;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;nucleobase-containing small molecule metabolic process#GO:0055086;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;isoprenoid biosynthetic process#GO:0008299 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Cholesterol biosynthesis#P00014>Phosphomevalonate kinase#P00500 DROME|FlyBase=FBgn0037327|UniProtKB=Q9NIV1 Q9NIV1 PEK PTHR11042:SF91 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0031456|UniProtKB=Q9VQG0 Q9VQG0 Tnpo-SR PTHR12363:SF42 TRANSPORTIN 3 AND IMPORTIN 13 TRANSPORTIN-3 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 transporter#PC00227 DROME|FlyBase=FBgn0037788|UniProtKB=Q9VH26 Q9VH26 CAH7 PTHR18952:SF141 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0004369|UniProtKB=P35832 P35832 Ptp99A PTHR19134:SF577 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE 99A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182 protein phosphatase#PC00195;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032596|UniProtKB=Q9VJJ0 Q9VJJ0 Prosbeta4 PTHR11599:SF6 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-2 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033890|UniProtKB=Q494K2 Q494K2 Ctf4 PTHR19932:SF10 WD REPEAT AND HMG-BOX DNA BINDING PROTEIN WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0037875|UniProtKB=Q9VGS1 Q9VGS1 ZnT86D PTHR45755:SF6 FAMILY NOT NAMED ZINC TRANSPORTER 7 zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;Golgi stack#GO:0005795;intracellular vesicle#GO:0097708 DROME|Gene_ORFName=Dmel_CG46514|UniProtKB=A0ACD4DAX0 A0ACD4DAX0 CG46514 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0037146|UniProtKB=Q9VNW6 Q9VNW6 P5CS PTHR11063:SF28 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0033582|UniProtKB=A0A0B4KEL2 A0A0B4KEL2 Dmel\CG9084 PTHR23248:SF4 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;cellular component organization#GO:0016043;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0037236|UniProtKB=Q7YZ95 Q7YZ95 Skp2 PTHR16134:SF160 F-BOX/TPR REPEAT PROTEIN POF3 S-PHASE KINASE-ASSOCIATED PROTEIN 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0037354|UniProtKB=Q9VNF3 Q9VNF3 Dmel\CG12171 PTHR43975:SF6 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED DROME|FlyBase=FBgn0028916|UniProtKB=Q7KT91 Q7KT91 CG33090 PTHR12654:SF0 BILE ACID BETA-GLUCOSIDASE-RELATED NON-LYSOSOMAL GLUCOSYLCERAMIDASE glucosidase#PC00108;hydrolase#PC00121 DROME|FlyBase=FBgn0035332|UniProtKB=Q9W024 Q9W024 Dmel\CG13801 PTHR43568:SF1 P PROTEIN CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0035591|UniProtKB=Q9VRJ7 Q9VRJ7 Dmel\CG4611 PTHR24014:SF6 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;tRNA binding#GO:0000049 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mitochondrial RNA modification#GO:1900864;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;tRNA 3'-end processing#GO:0042780;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032660|UniProtKB=Q9VJB0 Q9VJB0 elfless PTHR47094:SF1 ELFLESS, ISOFORM B ELFLESS, ISOFORM B catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0003090|UniProtKB=A1Z6W3 A1Z6W3 pk PTHR24211:SF20 LIM DOMAIN-CONTAINING PROTEIN PROTEIN ESPINAS-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030246|UniProtKB=Q9VZ55 Q9VZ55 Dmel\CG1582 PTHR18934:SF145 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX57-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0035737|UniProtKB=Q9VS14 Q9VS14 Cpr65Ec PTHR10380:SF230 CUTICLE PROTEIN CUTICULAR PROTEIN 47EE-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0267790|UniProtKB=Q9VHC7 Q9VHC7 rump PTHR23003:SF71 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN FI21236P1-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0032620|UniProtKB=Q9VJG2 Q9VJG2 cg12288 PTHR23236:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H RNA-BINDING PROTEIN 34 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 DROME|FlyBase=FBgn0263353|UniProtKB=Q9VNI6 Q9VNI6 dths PTHR14309:SF10 EXPRESSED PROTEIN PH DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0287724|UniProtKB=M9PD84 M9PD84 Ca-beta PTHR11824:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT CA2+-CHANNEL-PROTEIN-BETA-SUBUNIT, ISOFORM L voltage-gated ion channel#PC00241 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587 DROME|FlyBase=FBgn0036879|UniProtKB=Q9VW03 Q9VW03 Cpr76Bb PTHR12236:SF104 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 64AC-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0083984|UniProtKB=A4V381 A4V381 Dmel\CG34148 PTHR34651:SF1 SIMILAR TO ENSANGP00000021391 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 61 DROME|FlyBase=FBgn0031609|UniProtKB=Q9VR04 Q9VR04 Dmel\CG15443 PTHR16356:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 DROME|FlyBase=FBgn0041623|UniProtKB=P82984 P82984 Or65c PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0085324|UniProtKB=A8JRF1 A8JRF1 Dmel\CG34295 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034470|UniProtKB=Q8SY61 Q8SY61 Obp56d PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0039004|UniProtKB=Q9VCW3 Q9VCW3 Nup133 PTHR13405:SF11 NUCLEAR PORE COMPLEX PROTEIN NUP133 NUCLEAR PORE COMPLEX PROTEIN NUP133 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 gene expression#GO:0010467;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;cellular component organization#GO:0016043;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913 organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643 DROME|FlyBase=FBgn0039636|UniProtKB=Q9VAP6 Q9VAP6 Atg14 PTHR13664:SF0 BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;protein-membrane adaptor activity#GO:0043495;molecular function regulator activity#GO:0098772;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;organelle localization#GO:0051640;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;localization#GO:0051179;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to nutrient levels#GO:0031669;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423 extrinsic component of membrane#GO:0019898;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;transferase complex, transferring phosphorus-containing groups#GO:0061695;phosphatidylinositol 3-kinase complex, class III#GO:0035032;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 DROME|FlyBase=FBgn0033917|UniProtKB=Q7K561 Q7K561 SmydA-1 PTHR46455:SF4 SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A GH11294P intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0027889|UniProtKB=Q7KRY6 Q7KRY6 ball PTHR11909:SF539 CASEIN KINASE-RELATED NUCLEOSOMAL HISTONE KINASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0037021|UniProtKB=Q9VPB7 Q9VPB7 Pcif1 PTHR21727:SF0 PHOSPHORYLATED CTD INTERACTING FACTOR 1 MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0085472|UniProtKB=A8DYD6 A8DYD6 CG30070 PTHR21398:SF22 AGAP007094-PA IP12060P-RELATED DROME|FlyBase=FBgn0037093|UniProtKB=Q9VP22 Q9VP22 Cdk12 PTHR24056:SF597 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 12 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of cellular process#GO:0050794;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003300|UniProtKB=P22814 P22814 run PTHR11950:SF51 RUNT RELATED SEGMENTATION PROTEIN RUNT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 DROME|FlyBase=FBgn0029723|UniProtKB=Q9W4H3 Q9W4H3 Proc-R PTHR46641:SF11 FMRFAMIDE RECEPTOR-RELATED PROCTOLIN RECEPTOR, ISOFORM A neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0022984|UniProtKB=O44434 O44434 qkr58E-3 PTHR11208:SF140 RNA-BINDING PROTEIN RELATED GH05812P-RELATED RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0052808|UniProtKB=Q8IRX5 Q8IRX5 Dmel\CG32808 PTHR24276:SF100 POLYSERASE-RELATED FI18310P1-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039013|UniProtKB=Q9VCV3 Q9VCV3 Rnf220 PTHR13459:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 DROME|FlyBase=FBgn0085434|UniProtKB=Q9W0Y8 Q9W0Y8 NaCP60E PTHR10037:SF303 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN 60E monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 action potential#GO:0001508;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;sodium channel complex#GO:0034706;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0286199|UniProtKB=Q9VCA1 Q9VCA1 shps PTHR43563:SF1 AMINE OXIDASE MONOAMINE OXIDASE oxidase#PC00175;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 DROME|FlyBase=FBgn0016041|UniProtKB=Q9U4L6 Q9U4L6 Tom40 PTHR10802:SF2 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG 1-RELATED transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular transport#GO:0046907;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585 mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0267709|UniProtKB=A0A6H2EG72 A0A6H2EG72 CR46042 PTHR23259:SF82 RIDDLE TIL DOMAIN-CONTAINING PROTEIN protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0030058|UniProtKB=Q9W3C6 Q9W3C6 Dmel\CG11294 PTHR24329:SF569 HOMEOBOX PROTEIN ARISTALESS IP01065P sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0053306|UniProtKB=Q7KTA2 Q7KTA2 DS00941.11 PTHR20993:SF0 GH07914P GH07914P DROME|FlyBase=FBgn0011766|UniProtKB=Q27368 Q27368 E2f1 PTHR12081:SF18 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F2-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 p53 pathway feedback loops 2#P04398>E2F-1#P04652;Cell cycle#P00013>E2F#P00488;p53 pathway#P00059>E2F-1#P04627 DROME|FlyBase=FBgn0035323|UniProtKB=Q9W033 Q9W033 Dmel\CG13807 PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;RNA binding#GO:0003723;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034419|UniProtKB=A1ZBH3 A1ZBH3 Dmel\CG15111 PTHR12277:SF194 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN FI04476P hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824 organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;acylglycerol catabolic process#GO:0046464;glycerophospholipid catabolic process#GO:0046475;neutral lipid metabolic process#GO:0006638;neutral lipid catabolic process#GO:0046461;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid metabolic process#GO:0006650;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 serine protease#PC00203 DROME|FlyBase=FBgn0034518|UniProtKB=Q7K1E3 Q7K1E3 CG18065-RA PTHR24276:SF97 POLYSERASE-RELATED GH13245P2-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003267|UniProtKB=P10181 P10181 ro PTHR45946:SF4 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN ROUGH-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0035518|UniProtKB=Q9VZF2 Q9VZF2 cg15011 PTHR12360:SF1 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 NF-X1-TYPE ZINC FINGER PROTEIN NFXL1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0288966|UniProtKB=O62609 O62609 Med PTHR13703:SF45 SMAD SMAD FAMILY MEMBER 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to growth factor stimulus#GO:0071363;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 SCW signaling pathway#P06216>MED#P06323;GBB signaling pathway#P06214>MED#P06299;TGF-beta signaling pathway#P00052>Co-Smads#P01276;DPP-SCW signaling pathway#P06212>MED#P06265;DPP signaling pathway#P06213>MED#P06279;MYO signaling pathway#P06215>MED#P06311;Activin beta signaling pathway#P06210>MED#P06233;TGF-beta signaling pathway#P00052>RSmads#P01292;BMP/activin signaling pathway-drosophila#P06211>Co-Smad#P06254;ALP23B signaling pathway#P06209>MED#P06221 DROME|FlyBase=FBgn0053182|UniProtKB=Q9V6L0 Q9V6L0 Kdm4B PTHR10694:SF129 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4B-RELATED histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0039518|UniProtKB=Q9VB32 Q9VB32 Dmel\CG13978 PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 extracellular matrix glycoprotein#PC00100 DROME|FlyBase=FBgn0010470|UniProtKB=A0A0B4K7C5 A0A0B4K7C5 Fkbp14 PTHR45779:SF14 PEPTIDYLPROLYL ISOMERASE PEPTIDYLPROLYL ISOMERASE catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0035906|UniProtKB=Q9VSL5 Q9VSL5 GstO2 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;transferase activity#GO:0016740;antioxidant activity#GO:0016209;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364 sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0036298|UniProtKB=Q9VTZ4 Q9VTZ4 nst PTHR45955:SF1 PHOSPHOACETYLGLUCOSAMINE MUTASE PHOSPHOACETYLGLUCOSAMINE MUTASE isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;UDP-N-acetylglucosamine biosynthetic process#GO:0006048 isomerase#PC00135;mutase#PC00160 DROME|FlyBase=FBgn0262866|UniProtKB=Q9VR61 Q9VR61 S6kII PTHR24351:SF110 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Interleukin signaling pathway#P00036>p90RSK#P00964;PDGF signaling pathway#P00047>p90RSK#P01142 DROME|FlyBase=FBgn0034002|UniProtKB=Q7K0W0 Q7K0W0 Dmel\CG8079 PTHR23106:SF25 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 LD27413P cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0038045|UniProtKB=Q9VG74 Q9VG74 Nans PTHR42966:SF1 N-ACETYLNEURAMINATE SYNTHASE N-ACETYLNEURAMINATE-9-PHOSPHATE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032017|UniProtKB=Q9VLP6 Q9VLP6 Dmel\CG7810 PTHR31840:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 DROME|FlyBase=FBgn0035598|UniProtKB=Q9VRK6 Q9VRK6 Dmel\CG4669 PTHR40552:SF6 AT05186P-RELATED FI09606P-RELATED DROME|FlyBase=FBgn0025879|UniProtKB=Q9VH14 Q9VH14 Timp PTHR11844:SF25 METALLOPROTEASE INHIBITOR TISSUE INHIBITOR OF METALLOPROTEINASE enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0003028|UniProtKB=P51521 P51521 ovo PTHR10032:SF271 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS RH12261P-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;epidermis development#GO:0008544;developmental process#GO:0032502;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0051103|UniProtKB=Q9VBV9 Q9VBV9 Dmel\CG31103 PTHR23511:SF37 SYNAPTIC VESICLE GLYCOPROTEIN 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0052702|UniProtKB=Q9W332 Q9W332 Cubn PTHR46335:SF1 CUBILIN CUBILIN DROME|FlyBase=FBgn0041604|UniProtKB=Q9VUG1 Q9VUG1 dlp PTHR10822:SF30 GLYPICAN DALLY-LIKE, ISOFORM A regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell surface#GO:0009986;cell junction#GO:0030054;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0029909|UniProtKB=Q9W3V5 Q9W3V5 mAChR-C PTHR24249:SF414 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR LP14436P postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0036915|UniProtKB=Q9VW52 Q9VW52 Prp3 PTHR14212:SF0 U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;organelle#GO:0043226;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA splicing factor#PC00148 mRNA splicing#P00058>U6#P01473;mRNA splicing#P00058>U4#P01476 DROME|FlyBase=FBgn0034382|UniProtKB=Q6NN18 Q6NN18 mElo PTHR11157:SF116 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0031689|UniProtKB=Q9VMT5 Q9VMT5 Cyp28d1 PTHR24292:SF84 CYTOCHROME P450 CYTOCHROME P450 28A5-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0052706|UniProtKB=Q8IRM9 Q8IRM9 Dmel\CG32706 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component assembly#GO:0022607;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0037206|UniProtKB=Q9VNP4 Q9VNP4 Dmel\CG12768 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0004782|UniProtKB=O97059 O97059 Ccp84Ab PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0028471|UniProtKB=Q9V3H9 Q9V3H9 Nab2 PTHR14738:SF29 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0034783|UniProtKB=Q9W1Z1 Q9W1Z1 Dmel\CG9825 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0053770|UniProtKB=Q4ABH6 Q4ABH6 Dmel\CG33770 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0261584|UniProtKB=A0A0B4JD89 A0A0B4JD89 Dmel\CG42694 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0039110|UniProtKB=Q9VCI7 Q9VCI7 RanBP3 PTHR23138:SF186 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3-RELATED nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032373|UniProtKB=Q9VKF6 Q9VKF6 Vha100-5 PTHR11629:SF61 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;enzyme binding#GO:0019899;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;binding#GO:0005488 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;proton transmembrane transport#GO:1902600;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 vacuolar membrane#GO:0005774;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533 ATP synthase#PC00002 DROME|FlyBase=FBgn0265184|UniProtKB=A0A0B4LGA2 A0A0B4LGA2 Snrnp65 PTHR16105:SF0 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING REGION-CONTAINING PROTEIN 3 pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 DROME|FlyBase=FBgn0064116|UniProtKB=Q9VRG6 Q9VRG6 Acbp-Ank PTHR24119:SF0 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 heterocyclic compound binding#GO:1901363;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0013681|UniProtKB=P18930 P18930 mt:ND3 PTHR11058:SF26 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 NADH dehydrogenase activity#GO:0003954;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;electron transfer activity#GO:0009055;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0031142|UniProtKB=Q9VRD3 Q9VRD3 r-cup PTHR21391:SF0 AT04489P-RELATED AT04489P-RELATED DROME|FlyBase=FBgn0014028|UniProtKB=P21914 P21914 SdhB PTHR11921:SF47 SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039719|UniProtKB=A0A0B4KI23 A0A0B4KI23 BcDNA:RE21592 PTHR10380:SF192 CUTICLE PROTEIN CUTICULAR PROTEIN 65AU, ISOFORM A-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0039443|UniProtKB=Q9VBD3 Q9VBD3 TwdlS PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 DROME|FlyBase=FBgn0031544|UniProtKB=Q9VQR9 Q9VQR9 Dmel\CG17593 PTHR12883:SF0 ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED PAT COMPLEX SUBUNIT CCDC47 cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 DROME|FlyBase=FBgn0030375|UniProtKB=Q9VYP6 Q9VYP6 Dmel\CG11356 PTHR45697:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 DROME|FlyBase=FBgn0052850|UniProtKB=Q8SX35 Q8SX35 Rnf11 PTHR46359:SF2 GEO07743P1 GEO07743P1 DROME|FlyBase=FBgn0032150|UniProtKB=Q9VL80 Q9VL80 Dmel\CG13123 PTHR10032:SF271 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS RH12261P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 developmental process#GO:0032502;epidermis development#GO:0008544;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0033110|UniProtKB=A1Z6Q3 A1Z6Q3 Dmel\CG9447 PTHR11161:SF22 O-ACYLTRANSFERASE ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0035043|UniProtKB=Q9W128 Q9W128 CT15357 PTHR45617:SF170 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 32 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0265268|UniProtKB=Q9VVQ5 Q9VVQ5 anon-SAGE:Wang-055 PTHR10869:SF216 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROCOLLAGEN-PROLINE 4-DIOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 oxidoreductase complex#GO:1990204;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0024811|UniProtKB=Q9XYM0 Q9XYM0 Crk PTHR19969:SF5 SH2-SH3 ADAPTOR PROTEIN-RELATED ADAPTER MOLECULE CRK receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling receptor binding#GO:0005102;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Crk#P00207 DROME|FlyBase=FBgn0037852|UniProtKB=Q7K0L7 Q7K0L7 Tpc1 PTHR24089:SF59 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;vitamin transport#GO:0051180;organophosphate ester transport#GO:0015748 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 DROME|FlyBase=FBgn0034261|UniProtKB=A1ZAX8 A1ZAX8 HPS4 PTHR14407:SF11 HERMANSKY-PUDLAK SYNDROME 4 PROTEIN LIGHT-EAR PROTEIN-RELATED HERMANSKY-PUDLAK SYNDROME 4, ISOFORM A guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 localization#GO:0051179;protein targeting#GO:0006605;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184 protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0040890|UniProtKB=Q9VWH8 Q9VWH8 ksh PTHR13229:SF2 PROTEIN KISH-A PROTEIN KISH-A transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;protein secretion#GO:0009306;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;establishment of protein localization#GO:0045184;export from cell#GO:0140352 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0033739|UniProtKB=A8DYB7 A8DYB7 Dyb PTHR12268:SF27 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN, ISOFORM F plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0053475|UniProtKB=A1Z887 A1Z887 Dmel\CG33475 PTHR20898:SF1 DAEDALUS ON 3-RELATED-RELATED MD-2-RELATED LIPID-RECOGNITION DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0085377|UniProtKB=Q9VZ05 Q9VZ05 CG15197 PTHR22753:SF14 TRANSMEMBRANE PROTEIN 68 DGAT1_2-INDEPENDENT ENZYME SYNTHESIZING STORAGE LIPIDS membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033108|UniProtKB=Q0E9N0 Q0E9N0 Dmel\CG15236 PTHR14445:SF36 GRB10 INTERACTING GYF PROTEIN FI03272P-RELATED translation regulator activity#GO:0045182 regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0011205|UniProtKB=Q9NHN2 Q9NHN2 fbl PTHR12280:SF30 PANTOTHENATE KINASE PANTOTHENATE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 DROME|FlyBase=FBgn0033226|UniProtKB=Q5U191 Q5U191 puml PTHR42886:SF96 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;transferase activity#GO:0016740;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689 organophosphate biosynthetic process#GO:0090407;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987 lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034733|UniProtKB=Q9W247 Q9W247 Dmel\CG4752 PTHR11365:SF2 5-OXOPROLINASE RELATED 5-OXOPROLINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0262535|UniProtKB=M9ND39 M9ND39 Dmel\CG43089 PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0030121|UniProtKB=Q9W352 Q9W352 Cfp1 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188 DROME|FlyBase=FBgn0039059|UniProtKB=Q9VCQ2 Q9VCQ2 Dmel\CG13829 PTHR31792:SF6 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 HOMOLOG cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0000084|UniProtKB=P22465 P22465 AnxB10 PTHR10502:SF247 ANNEXIN ANNEXIN B10 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;anion binding#GO:0043168;ion binding#GO:0043167 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506 calcium-binding protein#PC00060 DROME|FlyBase=FBgn0038619|UniProtKB=Q9VE71 Q9VE71 Dmel\CG7685 PTHR12630:SF1 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA-RELATED biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0039536|UniProtKB=Q9VB11 Q9VB11 unc80 PTHR31781:SF1 UNC80 PROTEIN UNC-80 HOMOLOG monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 regulation of system process#GO:0044057;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;regulation of multicellular organismal process#GO:0051239;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;homeostatic process#GO:0042592 membrane#GO:0016020;membrane protein complex#GO:0098796;neuron projection#GO:0043005;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cation channel complex#GO:0034703;axon#GO:0030424;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706 DROME|FlyBase=FBgn0065110|UniProtKB=Q86LH1 Q86LH1 ppk10 PTHR11690:SF179 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 10 monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0283678|UniProtKB=Q9VKH5 Q9VKH5 Osi21 PTHR21879:SF15 FI03362P-RELATED-RELATED OSIRIS 21 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0039337|UniProtKB=Q9VBQ9 Q9VBQ9 MED28 PTHR13512:SF2 MEDIATOR COMPLEX SUBUNIT 28 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 28 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0001978|UniProtKB=P40798 P40798 stc PTHR12360:SF16 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 TRANSCRIPTIONAL REPRESSOR NF-X1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0031315|UniProtKB=Q7KU06 Q7KU06 Dmel\CG14341 PTHR17005:SF3 MALE-ENHANCED ANTIGEN-1 MALE-ENHANCED ANTIGEN 1 DROME|FlyBase=FBgn0026598|UniProtKB=Q9Y1T2 Q9Y1T2 Apc2 PTHR12607:SF13 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY APC-LIKE, ISOFORM A-RELATED beta-catenin binding#GO:0008013;protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cell fate commitment#GO:0045165;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of signal transduction#GO:0009968;nervous system development#GO:0007399;regulation of protein-containing complex disassembly#GO:0043244;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of microtubule-based process#GO:0032886;pattern specification process#GO:0007389;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;cellular developmental process#GO:0048869;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell migration#GO:0016477;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of protein depolymerization#GO:1901880 plasma membrane protein complex#GO:0098797;cytoplasmic microtubule#GO:0005881;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cell periphery#GO:0071944;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;polymeric cytoskeletal fiber#GO:0099513;extrinsic component of plasma membrane#GO:0019897;membraneless organelle#GO:0043228;extrinsic component of membrane#GO:0019898 Angiogenesis#P00005>APC#P00195;Wnt signaling pathway#P00057>APC#P01468 DROME|FlyBase=FBgn0027868|UniProtKB=Q9V466 Q9V466 Nup107 PTHR13003:SF2 NUP107-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP107 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein transport#GO:0015031;protein import into nucleus#GO:0006606;cellular component organization#GO:0016043;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;biosynthetic process#GO:0009058 nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967 transporter#PC00227 DROME|FlyBase=FBgn0086356|UniProtKB=A1Z9I5 A1Z9I5 tum PTHR46199:SF3 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 nuclear division#GO:0000280;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;Rho protein signal transduction#GO:0007266;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of biological process#GO:0050789;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;signaling#GO:0023052;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;intracellular signaling cassette#GO:0141124;organelle assembly#GO:0070925;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular response to stimulus#GO:0051716;cell division#GO:0051301;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;intracellular organelle#GO:0043229;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;midbody#GO:0030496;intracellular protein-containing complex#GO:0140535;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;cell division site#GO:0032153;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020 G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0000287|UniProtKB=Q9VKH3 Q9VKH3 salr PTHR23233:SF84 SAL-LIKE PROTEIN FI23031P1-RELATED DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0038313|UniProtKB=Q9VFA0 Q9VFA0 Dmel\CG4338 PTHR20426:SF0 RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG 18S RRNA AMINOCARBOXYPROPYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0035795|UniProtKB=Q9VS86 Q9VS86 Dmel\CG16998 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0024510|UniProtKB=Q8T626 Q8T626 dlt PTHR28678:SF1 CODANIN-1 CODANIN-1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0034879|UniProtKB=Q9W1M9 Q9W1M9 Rrp4 PTHR21321:SF4 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP4 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 RNA processing factor#PC00147 DROME|FlyBase=FBgn0030883|UniProtKB=Q9VX02 Q9VX02 bs13c01.y1 PTHR11001:SF2 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 mitochondrial fission#GO:0000266;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0035789|UniProtKB=Q9VS77 Q9VS77 mthl6 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0263289|UniProtKB=Q7KRY7 Q7KRY7 scrib PTHR23119:SF44 DISCS LARGE PROTEIN LAP4 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 protein localization to cell junction#GO:1902414;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;endosome to plasma membrane protein transport#GO:0099638;biological regulation#GO:0065007;establishment or maintenance of cell polarity#GO:0007163;receptor clustering#GO:0043113;cell adhesion#GO:0007155;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;protein transport#GO:0015031;protein localization to membrane#GO:0072657;endocytic recycling#GO:0032456;protein localization to cell periphery#GO:1990778;intracellular protein transport#GO:0006886;protein localization to synapse#GO:0035418;endosomal transport#GO:0016197;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;establishment of protein localization to membrane#GO:0090150;cell-cell adhesion#GO:0098609;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 postsynapse#GO:0098794;basal part of cell#GO:0045178;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054;adherens junction#GO:0005912 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0029697|UniProtKB=Q9W4M4 Q9W4M4 Dmel\CG15570 PTHR12460:SF0 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN CID DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 DROME|FlyBase=FBgn0028946|UniProtKB=Q9V3Q2 Q9V3Q2 Or35a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038114|UniProtKB=A0A6F7RXE0 A0A6F7RXE0 Dmel\CG11670 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0033756|UniProtKB=Q8MQV5 Q8MQV5 BcDNA:SD21019 PTHR10218:SF365 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA Q SUBUNIT-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700 intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020;heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Endothelin signaling pathway#P00019>Gq#P00586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Wnt signaling pathway#P00057>Galpha#P01451;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057 DROME|FlyBase=FBgn0023171|UniProtKB=Q7JY33 Q7JY33 rnh1 PTHR10642:SF35 RIBONUCLEASE H1 RIBONUCLEASE H1 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031;endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 DROME|FlyBase=FBgn0033633|UniProtKB=A1Z8L3 A1Z8L3 Smyd4-3 PTHR46165:SF6 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 SET AND MYND DOMAIN CONTAINING, CLASS 4, MEMBER 3 binding#GO:0005488;enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515 cellular process#GO:0009987;sensory system development#GO:0048880;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;cell development#GO:0048468;visual system development#GO:0150063;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0020381|UniProtKB=Q8IRY7 Q8IRY7 Dredd PTHR10454:SF232 CASPASE CASPASE-8 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;programmed cell death#GO:0012501;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;positive regulation of apoptotic process#GO:0043065 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0038454|UniProtKB=Q9VES0 Q9VES0 Gpkow PTHR15818:SF2 G PATCH AND KOW-CONTAINING G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0039617|UniProtKB=Q9VAR6 Q9VAR6 DIP-gamma PTHR12231:SF105 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN GAMMA protein binding#GO:0005515;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;cell adhesion#GO:0007155;synapse organization#GO:0050808 cell junction#GO:0030054;cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0037937|UniProtKB=Q9VGJ5 Q9VGJ5 fer3 PTHR23349:SF63 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FER3-LIKE PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0028399|UniProtKB=M9PFR2 M9PFR2 Serinc PTHR10383:SF9 SERINE INCORPORATOR SERINE INCORPORATOR, ISOFORM F cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0036723|UniProtKB=Q9VVH0 Q9VVH0 Pykl4 PTHR11817:SF3 PYRUVATE KINASE AT14039P-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;pyruvate kinase activity#GO:0004743;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 DROME|FlyBase=FBgn0037405|UniProtKB=Q9VNL6 Q9VNL6 anon-f PTHR10913:SF45 FOLLISTATIN-RELATED AGRIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0039441|UniProtKB=Q9VBD5 Q9VBD5 TwdlN PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 DROME|FlyBase=FBgn0030734|UniProtKB=Q95TL8 Q95TL8 ERp44 PTHR46295:SF1 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020 DROME|FlyBase=FBgn0033439|UniProtKB=Q7K2L4 Q7K2L4 Dmel\CG1773 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0030851|UniProtKB=Q9VX38 Q9VX38 BEST:LD29336 PTHR21838:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0003074|UniProtKB=P52029 P52029 Pgi PTHR11469:SF1 GLUCOSE-6-PHOSPHATE ISOMERASE GLUCOSE-6-PHOSPHATE ISOMERASE small molecule binding#GO:0036094;binding#GO:0005488;monosaccharide binding#GO:0048029;isomerase activity#GO:0016853;carbohydrate binding#GO:0030246;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824 energy derivation by oxidation of organic compounds#GO:0015980;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Glucose-P-Isomerase#P03080;Glycolysis#P00024>Phosphoglucose isomerase#P00674 DROME|FlyBase=FBgn0040091|UniProtKB=Q9W228 Q9W228 Ugt317A1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0263846|UniProtKB=M9PC26 M9PC26 CG10020 PTHR47644:SF1 AGAP008221-PA PH DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0039491|UniProtKB=Q9VB71 Q9VB71 Dmel\CG6059 PTHR32083:SF0 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 structural protein#PC00211 DROME|FlyBase=FBgn0036598|UniProtKB=Q9VV22 Q9VV22 Dmel\CG4982 PTHR34931:SF4 FI02976P-RELATED GEO13385P1-RELATED DROME|Gene_ORFName=Dmel_CG46522|UniProtKB=A0ACD4DAW1 A0ACD4DAW1 CG46522 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component assembly#GO:0022607;gene expression#GO:0010467 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DROME|FlyBase=FBgn0031250|UniProtKB=Q9VPP0 Q9VPP0 Ent1 PTHR10332:SF88 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0085444|UniProtKB=A8DYH1 A8DYH1 mute PTHR16088:SF3 YY1 ASSOCIATED PROTEIN-RELATED GON-4-LIKE PROTEIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 DROME|FlyBase=FBgn0263998|UniProtKB=Q9I7F7 Q9I7F7 Ack-like PTHR24418:SF444 TYROSINE-PROTEIN KINASE ACTIVATED CDC42 KINASE-LIKE transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 DROME|FlyBase=FBgn0033891|UniProtKB=Q7K1S1 Q7K1S1 Dmel\CG8067 PTHR13090:SF1 ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0033122|UniProtKB=Q7JQT8 Q7JQT8 Dmel\CG17002 PTHR22654:SF2 G PROTEIN PATHWAY SUPPRESSOR 2 G PROTEIN PATHWAY SUPPRESSOR 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0263396|UniProtKB=Q08473 Q08473 sqd PTHR48033:SF10 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN RNA-BINDING PROTEIN SQUID binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032478|UniProtKB=Q9VK29 Q9VK29 Rsph1 PTHR43215:SF18 RADIAL SPOKE HEAD 1 HOMOLOG RADIAL SPOKE HEAD 1 HOMOLOG sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 nucleus#GO:0005634;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0035568|UniProtKB=Q9VZ93 Q9VZ93 anon-WO0140519.190 PTHR45618:SF9 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL 2-OXOGLUTARATE_MALATE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0034415|UniProtKB=Q4V6H2 Q4V6H2 Gpxl PTHR11592:SF78 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979 oxidoreductase#PC00176;peroxidase#PC00180 DROME|FlyBase=FBgn0033665|UniProtKB=Q8SWW2 Q8SWW2 Zip48C PTHR11040:SF211 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP11 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915 zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0031757|UniProtKB=Q9VMK1 Q9VMK1 Ucp4C PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;response to temperature stimulus#GO:0009266;response to cold#GO:0009409;response to stimulus#GO:0050896 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0036479|UniProtKB=Q9VUL2 Q9VUL2 Dmel\CG13458 PTHR28069:SF2 GH20023P GH20023P DROME|FlyBase=FBgn0038426|UniProtKB=Q9VEV5 Q9VEV5 mRpS33 PTHR13362:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S33 SMALL RIBOSOMAL SUBUNIT PROTEIN MS33 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0026268|UniProtKB=Q9VZ19 Q9VZ19 Antdh PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0026409|UniProtKB=Q0E8E8 Q0E8E8 Mpcp2 PTHR45671:SF10 SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 3 active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;phosphate transmembrane transporter activity#GO:0005315;secondary active transmembrane transporter activity#GO:0015291 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;phosphate ion transport#GO:0006817;transport#GO:0006810;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 mitochondrial carrier protein#PC00158 DROME|FlyBase=FBgn0039821|UniProtKB=Q9VA10 Q9VA10 Ktch PTHR12011:SF481 ADHESION G-PROTEIN COUPLED RECEPTOR FI21270P1-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0037070|UniProtKB=Q9VP51 Q9VP51 Dmel\CG11309 PTHR43329:SF4 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 DROME|FlyBase=FBgn0036154|UniProtKB=Q9VTH7 Q9VTH7 Dmel\CG6168 PTHR12283:SF6 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;acyltransferase activity#GO:0016746;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 DROME|FlyBase=FBgn0019928|UniProtKB=Q4V3S6 Q4V3S6 Ser8 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0029896|UniProtKB=Q9W3W9 Q9W3W9 LP06294.5prime PTHR23511:SF34 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2B ISOFORM X1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0036398|UniProtKB=Q9VUB5 Q9VUB5 upSET PTHR46462:SF3 UPSET, ISOFORM A UPSET, ISOFORM A regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Rpd3L-Expanded complex#GO:0070210;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0028940|UniProtKB=Q9V419 Q9V419 Cyp28a5 PTHR24292:SF84 CYTOCHROME P450 CYTOCHROME P450 28A5-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0032961|UniProtKB=Q9V9Q4 Q9V9Q4 Dmel\CG1416 PTHR13009:SF22 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 ACTIVATOR OF 90 KDA HEAT SHOCK PROTEIN ATPASE HOMOLOG 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0027356|UniProtKB=Q7KLE5 Q7KLE5 Amph PTHR46514:SF3 AMPHIPHYSIN AMPHIPHYSIN binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0267978|UniProtKB=P29673 P29673 ap PTHR24208:SF168 LIM/HOMEOBOX PROTEIN LHX PROTEIN APTEROUS DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0022382|UniProtKB=P81900 P81900 Pka-R2 PTHR11635:SF152 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Cell cycle#P00013>Protein kinase subunit#P00482;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Endothelin signaling pathway#P00019>PKA#P00570;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035 DROME|FlyBase=FBgn0038609|UniProtKB=Q9VE85 Q9VE85 Nup43 PTHR22652:SF0 NUCLEOPORIN NUP43 NUCLEOPORIN NUP43 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0266195|UniProtKB=Q9VEA4 Q9VEA4 Tgs1 PTHR14741:SF32 S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED TRIMETHYLGUANOSINE SYNTHASE catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0051441|UniProtKB=Q9VGQ6 Q9VGQ6 CG5135 PTHR24379:SF126 KRAB AND ZINC FINGER DOMAIN-CONTAINING LD25880P gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0038641|UniProtKB=Q9VE46 Q9VE46 ChT PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 DROME|FlyBase=FBgn0034313|UniProtKB=Q7JRH5 Q7JRH5 Dmel\CG5726 PTHR23254:SF16 EIF4G DOMAIN PROTEIN CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR translation regulator activity#GO:0045182 regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035243|UniProtKB=Q9W0C7 Q9W0C7 CG13926 PTHR12925:SF2 HIKESHI FAMILY MEMBER PROTEIN HIKESHI protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;binding#GO:0005488;molecular carrier activity#GO:0140104;protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0032632|UniProtKB=Q9VJE7 Q9VJE7 Dmel\CG6380 PTHR12398:SF20 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 phosphatase inhibitor#PC00183 DROME|FlyBase=FBgn0033191|UniProtKB=Q7JWD3 Q7JWD3 CG1598 PTHR10803:SF3 ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE ATPASE GET3 ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 endomembrane system organization#GO:0010256;membrane organization#GO:0061024;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein localization to organelle#GO:0033365;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 DROME|FlyBase=FBgn0004861|UniProtKB=P39769 P39769 ph-p PTHR12247:SF138 POLYCOMB GROUP PROTEIN L(3)MBT INTERACTOR IN OVARIAN SOMATIC CELLS, ISOFORM A-RELATED binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0004380|UniProtKB=Q9VRK9 Q9VRK9 Klp64D PTHR24115:SF472 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3A protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;organelle assembly#GO:0070925;axonal transport#GO:0098930;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;anterograde axonal transport#GO:0008089;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;axo-dendritic transport#GO:0008088;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0036619|UniProtKB=Q9VV46 Q9VV46 Cpr72Ec PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0038107|UniProtKB=Q9VG06 Q9VG06 Dmel\CG17327 PTHR12649:SF26 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DROME|FlyBase=FBgn0038715|UniProtKB=Q9VDW0 Q9VDW0 Dmel\CG7333 PTHR24064:SF467 SOLUTE CARRIER FAMILY 22 MEMBER FI01439P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0031077|UniProtKB=Q9VWB9 Q9VWB9 THADA PTHR14387:SF7 THADA/DEATH RECEPTOR INTERACTING PROTEIN TRNA (32-2'-O)-METHYLTRANSFERASE REGULATOR THADA enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 RNA metabolic process#GO:0016070;methylation#GO:0032259;calcium ion homeostasis#GO:0055074;RNA modification#GO:0009451;inorganic ion homeostasis#GO:0098771;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;tRNA modification#GO:0006400;intracellular monoatomic ion homeostasis#GO:0006873;tRNA processing#GO:0008033;intracellular calcium ion homeostasis#GO:0006874;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;gene expression#GO:0010467;RNA processing#GO:0006396;monoatomic ion homeostasis#GO:0050801;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA biosynthetic process#GO:0032774;homeostatic process#GO:0042592;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0028579|UniProtKB=Q9V9A8 Q9V9A8 phtf PTHR12680:SF6 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0263994|UniProtKB=Q9VXX6 Q9VXX6 CG15028 PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED ACTIN NUCLEATION-PROMOTING FACTOR WAS-RELATED binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267 regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0028884|UniProtKB=Q9VJM2 Q9VJM2 Dmel\CG4892 PTHR16284:SF13 PROTEIN CDV3 HOMOLOG PROTEIN CDV3 HOMOLOG cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0004509|UniProtKB=P26016 P26016 Fur1 PTHR42884:SF38 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 1, ISOFORMS 1_1-X_2 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;biological regulation#GO:0065007;proteolysis#GO:0006508;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;DPP signaling pathway#P06213>FUR1#P06290;BMP/activin signaling pathway-drosophila#P06211>Furin#P06244;Activin beta signaling pathway#P06210>FUR1#P06238;DPP-SCW signaling pathway#P06212>FUR1#P06263;GBB signaling pathway#P06214>FUR1#P06298;SCW signaling pathway#P06216>FUR1#P06333;Endothelin signaling pathway#P00019>furin#P00575;MYO signaling pathway#P06215>FUR1#P06318;ALP23B signaling pathway#P06209>FUR1#P06227;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 DROME|FlyBase=FBgn0034009|UniProtKB=Q5BI03 Q5BI03 Dmel\CG8155 PTHR22957:SF333 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 25 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;regulation of protein-containing complex disassembly#GO:0043244;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of autophagosome maturation#GO:1901096;regulation of macroautophagy#GO:0016241;regulation of catabolic process#GO:0009894 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0034691|UniProtKB=Q5U0V7 Q5U0V7 Synj PTHR11200:SF311 INOSITOL 5-PHOSPHATASE SYNAPTOJANIN-1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;cellular localization#GO:0051641;import into cell#GO:0098657;localization#GO:0051179;synaptic vesicle endocytosis#GO:0048488;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 Huntington disease#P00029>Synaptojanin#P00804 DROME|FlyBase=FBgn0264785|UniProtKB=Q8SX21 Q8SX21 Hph PTHR12907:SF26 EGL NINE HOMOLOG-RELATED HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASE DROME|FlyBase=FBgn0037445|UniProtKB=A0A0B4KGM5 A0A0B4KGM5 Dmel\CG9727 PTHR12619:SF21 RFX TRANSCRIPTION FACTOR FAMILY RFX-TYPE WINGED-HELIX DOMAIN-CONTAINING PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0038675|UniProtKB=Q9VE08 Q9VE08 Dmel\CG6013 PTHR21680:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0264776|UniProtKB=Q8IND7 Q8IND7 Dmel\CG44014 PTHR11430:SF32 LIPOCALIN CHLOROPLASTIC LIPOCALIN transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0038233|UniProtKB=Q9VFJ3 Q9VFJ3 HtrA2 PTHR22939:SF132 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA2, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;proteolysis#GO:0006508;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 serine protease#PC00203;protease#PC00190 DROME|FlyBase=FBgn0003129|UniProtKB=P23757 P23757 Poxm PTHR45636:SF16 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX POX-MESO PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0050005|UniProtKB=A1Z7X7 A1Z7X7 GstT2 PTHR43917:SF8 FAMILY NOT NAMED GH16740P-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 DROME|FlyBase=FBgn0086408|UniProtKB=Q9W1Z6 Q9W1Z6 stl PTHR13723:SF275 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE STALL, ISOFORM C metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0053912|UniProtKB=Q4ABI1 Q4ABI1 Dmel\CG33912 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0011740|UniProtKB=Q24451 Q24451 alpha-Man-IIa PTHR11607:SF73 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;glycosidase#PC00110 DROME|FlyBase=FBgn0036199|UniProtKB=Q7K566 Q7K566 Bmcp PTHR45618:SF21 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN BMCP transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0039965|UniProtKB=Q9W5N0 Q9W5N0 Coa7 PTHR13891:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0034371|UniProtKB=Q7KIS4 Q7KIS4 Ntan1 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0085442|UniProtKB=A6MHQ4 A6MHQ4 NKAIN PTHR13084:SF6 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0029648|UniProtKB=Q9W4U2 Q9W4U2 BcDNA:RH09070 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;binding#GO:0005488;catalytic activity#GO:0003824;small molecule binding#GO:0036094;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 oxidoreductase#PC00176 DROME|FlyBase=FBgn0036124|UniProtKB=Q9VTE6 Q9VTE6 Noc1 PTHR12048:SF0 CCAAT-BINDING FACTOR-RELATED CCAAT_ENHANCER-BINDING PROTEIN ZETA intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0039831|UniProtKB=Q9V9Z6 Q9V9Z6 Dmel\CG12054 PTHR23057:SF0 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0052654|UniProtKB=X2JEM2 X2JEM2 Sec16 PTHR13402:SF6 RGPR-RELATED SECRETORY 16, ISOFORM I transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0039480|UniProtKB=Q9VB82 Q9VB82 Cpr97Ea PTHR10380:SF249 CUTICLE PROTEIN CUTICULAR PROTEIN 97EA, ISOFORM A extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0031462|UniProtKB=Q9VQH0 Q9VQH0 Pykl2 PTHR11817:SF3 PYRUVATE KINASE AT14039P-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;nucleobase-containing compound metabolic process#GO:0006139;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 DROME|FlyBase=FBgn0038320|UniProtKB=Q9VF87 Q9VF87 Cyfip PTHR12195:SF6 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of protein metabolic process#GO:0051246;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;anatomical structure development#GO:0048856;system development#GO:0048731;axon guidance#GO:0007411;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;neuron projection guidance#GO:0097485 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 DROME|FlyBase=FBgn0030012|UniProtKB=Q9W3J0 Q9W3J0 Imzf PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032689|UniProtKB=Q9VJ75 Q9VJ75 Dmel\CG10413 PTHR11827:SF100 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 9 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108 transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0020655|UniProtKB=Q9VTX5 Q9VTX5 ArfGAP1 PTHR46395:SF1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of endocytosis#GO:0030100;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 G-protein modulator#PC00022;GTPase-activating protein#PC00257 Integrin signalling pathway#P00034>ASAP1#P00909 DROME|FlyBase=FBgn0030330|UniProtKB=Q7K187 Q7K187 Tango10 PTHR24410:SF41 HL07962P-RELATED HL07962P defense/immunity protein#PC00090 DROME|FlyBase=FBgn0086768|UniProtKB=Q27869 Q27869 Pcmt PTHR11579:SF0 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;O-methyltransferase activity#GO:0008171 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 methyltransferase#PC00155;transferase#PC00220 DROME|FlyBase=FBgn0034481|UniProtKB=A1ZBR3 A1ZBR3 Dmel\CG11041 PTHR46763:SF2 DYNEIN REGULATORY COMPLEX PROTEIN 8 DYNEIN REGULATORY COMPLEX PROTEIN 8 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0022699|UniProtKB=Q9VRV4 Q9VRV4 D19B PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0003116|UniProtKB=O18399 O18399 pn PTHR12112:SF39 BNIP - RELATED EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN) hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0037912|UniProtKB=Q7KSQ0 Q7KSQ0 sea PTHR45788:SF4 SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL active transmembrane transporter activity#GO:0022804;citrate transmembrane transporter activity#GO:0015137;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;citrate transport#GO:0015746;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;tricarboxylic acid transport#GO:0006842 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0034579|UniProtKB=Q9W2M8 Q9W2M8 mRpL54 PTHR28595:SF1 39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML54 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0264308|UniProtKB=A0A6H2EJZ8 A0A6H2EJZ8 hbt PTHR12242:SF55 OS02G0130600 PROTEIN-RELATED HEADBUTT, ISOFORM E membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0040341|UniProtKB=Q9V3J7 Q9V3J7 SP193 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0036165|UniProtKB=Q9VTI8 Q9VTI8 chrb PTHR12478:SF16 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 PROTEIN CHARYBDE-RELATED regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 DROME|FlyBase=FBgn0036227|UniProtKB=Q9VTR2 Q9VTR2 Dmel\CG17826 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0250788|UniProtKB=Q00963 Q00963 beta-Spec PTHR11915:SF462 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;actin filament-based process#GO:0030029;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;cell development#GO:0048468;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;organelle organization#GO:0006996;cellular process#GO:0009987 cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0260812|UniProtKB=A8JUS1 A8JUS1 inaF-D PTHR34929:SF1 ZGC:153157 INAF MOTIF CONTAINING 2 DROME|FlyBase=FBgn0040477|UniProtKB=Q9V6Q2 Q9V6Q2 cid PTHR11426:SF280 HISTONE H3 HISTONE H3 mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 DROME|FlyBase=FBgn0039727|UniProtKB=Q9VAD3 Q9VAD3 Vps13B PTHR12517:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B membrane traffic protein#PC00150 DROME|FlyBase=FBgn0010905|UniProtKB=M9NFI9 M9NFI9 Spn PTHR16154:SF6 NEURABIN NEURABIN-1 DROME|FlyBase=FBgn0030874|UniProtKB=Q9VX12 Q9VX12 Spt7 PTHR28598:SF1 STAGA COMPLEX 65 SUBUNIT GAMMA STAGA COMPLEX 65 SUBUNIT GAMMA transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 DROME|FlyBase=FBgn0035643|UniProtKB=M9PEQ7 M9PEQ7 Dmel\CG13287 PTHR16516:SF4 AGAP007109-PA PR DOMAIN ZINC FINGER PROTEIN 8-LIKE regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0020429|UniProtKB=Q9VMP3 Q9VMP3 GluRIIB PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536 postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 DROME|FlyBase=FBgn0030183|UniProtKB=Q9W2X7 Q9W2X7 Ypel PTHR13848:SF2 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0037622|UniProtKB=Q9VHM2 Q9VHM2 CG8202 PTHR13673:SF0 ESOPHAGEAL CANCER ASSOCIATED PROTEIN VPS35 ENDOSOMAL PROTEIN-SORTING FACTOR-LIKE vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0034045|UniProtKB=A1ZA52 A1ZA52 Dmel\CG8249 PTHR48021:SF89 FAMILY NOT NAMED FI02132P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0033124|UniProtKB=Q9NB13 Q9NB13 Tsp42Ec PTHR19282:SF521 TETRASPANIN AT12771P-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0024973|UniProtKB=O76912 O76912 Dmel\CG2701 PTHR21494:SF3 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 DROME|FlyBase=FBgn0259192|UniProtKB=Q9VQ68 Q9VQ68 Dmel\CG42296 PTHR23301:SF98 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED structural molecule activity#GO:0005198;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 DROME|FlyBase=FBgn0051021|UniProtKB=Q8IMH8 Q8IMH8 CG9708 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0023516|UniProtKB=O46085 O46085 Pex5 PTHR10130:SF0 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signal sequence receptor activity#GO:0005048 intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;protein transport#GO:0015031;peroxisomal transport#GO:0043574;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;peroxisome organization#GO:0007031;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;peroxisome#GO:0005777;cytosol#GO:0005829;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0034576|UniProtKB=Q7JYH3 Q7JYH3 ND-B14.7 PTHR21382:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0016797|UniProtKB=Q9VVX3 Q9VVX3 fz2 PTHR11309:SF90 FRIZZLED FRIZZLED-8 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;non-canonical Wnt signaling pathway#GO:0035567;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Angiogenesis#P00005>Fzd#P00189 DROME|FlyBase=FBgn0031724|UniProtKB=Q9VMP0 Q9VMP0 anon-WO0140519.54 PTHR23247:SF2 NY-REN-41 ANTIGEN L15 -RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 34 DROME|FlyBase=FBgn0053639|UniProtKB=Q9VWX4 Q9VWX4 CG16958 PTHR47760:SF1 G-PROTEIN COUPLED RECEPTOR B0563.6-LIKE PROTEIN-RELATED G PROTEIN-COUPLED RECEPTOR B0563.6-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031239|UniProtKB=Q9VPM2 Q9VPM2 Dmel\CG17075 PTHR22883:SF203 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0000448|UniProtKB=P31396 P31396 Hr3 PTHR45805:SF2 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR HORMONE RECEPTOR HR3-RELATED sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0250786|UniProtKB=Q7KU24 Q7KU24 Chd1 PTHR45623:SF14 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD1 catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676 cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0038546|UniProtKB=Q9VEF5 Q9VEF5 Dmel\CG7379 PTHR10333:SF89 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0035702|UniProtKB=Q9VRX0 Q9VRX0 Dmel\CG10147 PTHR24390:SF278 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 772 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0051450|UniProtKB=Q9VHQ0 Q9VHQ0 mRpS18A PTHR13479:SF66 30S RIBOSOMAL PROTEIN S18 LARGE RIBOSOMAL SUBUNIT PROTEIN ML66 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0004656|UniProtKB=P13709 P13709 fs(1)h PTHR22880:SF225 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS HOMEOTIC PROTEIN FEMALE STERILE-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0085478|UniProtKB=Q9W345 Q9W345 Zdhhc8 PTHR12349:SF2 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC8 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 DROME|FlyBase=FBgn0027596|UniProtKB=A8DYE0 A8DYE0 Kank PTHR24168:SF21 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KANK, ISOFORM D regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;regulation of protein-containing complex assembly#GO:0043254;negative regulation of cellular component organization#GO:0051129;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of actin filament length#GO:0030832;negative regulation of protein polymerization#GO:0032272;regulation of biological quality#GO:0065008;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0051217|UniProtKB=Q9VER6 Q9VER6 modSP PTHR24260:SF138 AT07769P-RELATED IP10340P-RELATED DROME|FlyBase=FBgn0015336|UniProtKB=Q9VXD4 Q9VXD4 Dmel\CG15865 PTHR10656:SF69 CELL FATE DETERMINING PROTEIN MAB21-RELATED MAB-21-LIKE HHH_H2TH-LIKE DOMAIN-CONTAINING PROTEIN nucleotidyltransferase#PC00174;transferase#PC00220 DROME|FlyBase=FBgn0054056|UniProtKB=Q9W0L4 Q9W0L4 dC1GalT6 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 transferase#PC00220 DROME|FlyBase=FBgn0032480|UniProtKB=Q9VK27 Q9VK27 Edem2 PTHR45679:SF2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycoprotein metabolic process#GO:0009100;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to unfolded protein#GO:0006986;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;carbohydrate derivative metabolic process#GO:1901135;cell communication#GO:0007154;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0036698|UniProtKB=Q9VVE3 Q9VVE3 Dmel\CG7724 PTHR10366:SF853 NAD DEPENDENT EPIMERASE/DEHYDRATASE GH25466P oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 metabolite interconversion enzyme#PC00262;dehydratase#PC00091;lyase#PC00144 DROME|FlyBase=FBgn0050195|UniProtKB=Q9W226 Q9W226 Dmel\CG30195 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033350|UniProtKB=Q7JXC6 Q7JXC6 Dmel\CG8237 PTHR13659:SF5 AUTOSOMAL HIGHLY CONSERVED PROTEIN PROTEIN FAM8A1 DROME|FlyBase=FBgn0002922|UniProtKB=P22816 P22816 nau PTHR11534:SF9 MYOGENIC FACTOR MYOGENIC-DETERMINATION PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0085391|UniProtKB=E1JIZ9 E1JIZ9 trv PTHR10352:SF93 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G TRIVET, ISOFORM I regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0035336|UniProtKB=Q9W020 Q9W020 CG9004 PTHR18034:SF4 CELL CYCLE CONTROL PROTEIN CWF22-RELATED NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 RNA processing factor#PC00147 DROME|FlyBase=FBgn0029693|UniProtKB=Q9W4N2 Q9W4N2 Cmtr1 PTHR16121:SF0 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0083963|UniProtKB=Q9VIC6 Q9VIC6 Nlg3 PTHR43903:SF30 NEUROLIGIN NEUROLIGIN 3, ISOFORM B signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;signaling#GO:0023052;endocytosis#GO:0006897;synapse assembly#GO:0007416;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;synaptic vesicle recycling#GO:0036465;multicellular organismal process#GO:0032501;developmental process#GO:0032502;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856 plasma membrane#GO:0005886;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0053172|UniProtKB=Q86B53 Q86B53 CG33172 PTHR14344:SF3 WD REPEAT PROTEIN TRNA (34-2'-O)-METHYLTRANSFERASE REGULATOR WDR6 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035914|UniProtKB=M9PET5 M9PET5 Dmel\CG6282 PTHR32251:SF15 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295) membrane#GO:0016020;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0035907|UniProtKB=Q9VSL6 Q9VSL6 GstO1 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;transferase activity#GO:0016740;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0033113|UniProtKB=A1Z6R4 A1Z6R4 Spn42Dc PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0029722|UniProtKB=Q9W4H4 Q9W4H4 Pdha2 PTHR11516:SF70 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0014859|UniProtKB=P49869 P49869 Hr38 PTHR24085:SF4 NUCLEAR HORMONE RECEPTOR NUCLEAR HORMONE RECEPTOR HR38-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor binding#GO:0140297;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565 response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to peptide hormone stimulus#GO:0071375;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0040849|UniProtKB=A1Z6D6 A1Z6D6 Ir41a PTHR42643:SF40 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 41A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0017556|UniProtKB=Q27575 Q27575 Prosalpha4T2 PTHR11599:SF237 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7-1-RELATED macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 nucleus#GO:0005634;proteasome complex#GO:0000502;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0031566|UniProtKB=Q9VQU3 Q9VQU3 Dmel\CG2818 PTHR22958:SF43 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid catabolic process#GO:0016042;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629;glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0033283|UniProtKB=Q5BI51 Q5BI51 Dmel\CG11635 PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0038966|UniProtKB=Q9VD09 Q9VD09 pinta PTHR10174:SF224 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED RETINOL-BINDING PROTEIN PINTA phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0002932|UniProtKB=P29503 P29503 neur PTHR12429:SF6 NEURALIZED PROTEIN NEURALIZED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;transport#GO:0006810;intracellular protein localization#GO:0008104;import into cell#GO:0098657;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;protein transport#GO:0015031;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;protein localization to organelle#GO:0033365;endocytosis#GO:0006897;regulation of cellular process#GO:0050794 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0040660|UniProtKB=Q0E8X8 Q0E8X8 BcDNA:RE33866 PTHR48417:SF1 ATP SYNTHASE F1 SUBUNIT EPSILON ATPASE INHIBITOR, MITOCHONDRIAL molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0038870|UniProtKB=Q9VDC9 Q9VDC9 Oga PTHR13170:SF16 O-GLCNACASE PROTEIN O-GLCNACASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 hydrolase#PC00121 DROME|FlyBase=FBgn0053777|UniProtKB=Q4ABK1 Q4ABK1 Dmel\CG33777 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0053700|UniProtKB=Q4ABI6 Q4ABI6 Dmel\CG33700 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0001291|UniProtKB=P18289 P18289 Jra PTHR11462:SF60 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JRA DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of transcription by RNA polymerase II#GO:0045944;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;response to lipid#GO:0033993;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;response to steroid hormone#GO:0048545;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838 DROME|FlyBase=FBgn0050035|UniProtKB=A1Z8N1 A1Z8N1 Tret1 PTHR48021:SF104 FAMILY NOT NAMED TREHALOSE TRANSPORTER 1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0041625|UniProtKB=P82982 P82982 Or65a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0029936|UniProtKB=Q9W3S4 Q9W3S4 Dmel\CG4617 PTHR46584:SF1 HMG DOMAIN-CONTAINING PROTEIN 4 HMG DOMAIN-CONTAINING PROTEIN 4 HMG box transcription factor#PC00024 DROME|FlyBase=FBgn0038613|UniProtKB=Q9VE77 Q9VE77 Vha100-4 PTHR11629:SF61 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A binding#GO:0005488;enzyme binding#GO:0019899;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;proton transmembrane transport#GO:1902600;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;cell periphery#GO:0071944;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471 ATP synthase#PC00002 DROME|FlyBase=FBgn0034786|UniProtKB=Q9W1Y8 Q9W1Y8 Spg11 PTHR13650:SF2 SPATACSIN SPATACSIN multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;synaptic vesicle localization#GO:0097479;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;establishment of vesicle localization#GO:0051650;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;neuron projection development#GO:0031175;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;microtubule-based transport#GO:0099111;establishment of organelle localization#GO:0051656;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;neurogenesis#GO:0022008;intracellular transport#GO:0046907;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;axo-dendritic transport#GO:0008088;axon development#GO:0061564;vesicle localization#GO:0051648;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;system development#GO:0048731;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;microtubule-based movement#GO:0007018;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268 neuron projection#GO:0043005;synapse#GO:0045202;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0016698|UniProtKB=Q9VQQ0 Q9VQQ0 Ptpa PTHR10012:SF0 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR protein phosphatase regulator activity#GO:0019888;cis-trans isomerase activity#GO:0016859;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;isomerase activity#GO:0016853;phosphatase activator activity#GO:0019211;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047 cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 phosphatase activator#PC00182 DROME|FlyBase=FBgn0000077|UniProtKB=Q9U4H5 Q9U4H5 amx PTHR21016:SF7 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of Notch signaling pathway#GO:0045747;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 DROME|FlyBase=FBgn0038203|UniProtKB=Q9VFN2 Q9VFN2 Or88a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0261564|UniProtKB=A0A0B4JCU3 A0A0B4JCU3 ReepA PTHR12300:SF197 HVA22-LIKE PROTEINS LP05237P-RELATED binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786;endomembrane system organization#GO:0010256 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasmic microtubule#GO:0005881;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;microtubule#GO:0005874;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0010235|UniProtKB=P46824 P46824 Klc PTHR45783:SF3 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 DROME|FlyBase=FBgn0039398|UniProtKB=Q9VBJ6 Q9VBJ6 Dmel\CG14540 PTHR23110:SF115 BTB DOMAIN TRANSCRIPTION FACTOR BTB DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0259196|UniProtKB=Q9VXT8 Q9VXT8 CG18620 PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665 protein modification by small protein conjugation or removal#GO:0070647;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;post-translational protein modification#GO:0043687 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0039747|UniProtKB=Q9VAA2 Q9VAA2 AdoR PTHR24246:SF61 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;G protein-coupled adenosine receptor signaling pathway#GO:0001973;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 DROME|FlyBase=FBgn0003462|UniProtKB=P61851 P61851 Sod1 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN]-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;copper ion binding#GO:0005507;catalytic activity#GO:0003824;antioxidant activity#GO:0016209 response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;response to reactive oxygen species#GO:0000302;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 oxidoreductase#PC00176 DROME|FlyBase=FBgn0001624|UniProtKB=P31007 P31007 dlg1 PTHR23119:SF51 DISCS LARGE DISKS LARGE 1 TUMOR SUPPRESSOR PROTEIN kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;nervous system development#GO:0007399;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;receptor clustering#GO:0043113;cell adhesion#GO:0007155;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;developmental process#GO:0032502;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;anatomical structure development#GO:0048856;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;protein localization to cell junction#GO:1902414;establishment or maintenance of apical/basal cell polarity#GO:0035088;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268 synaptic membrane#GO:0097060;neuromuscular junction#GO:0031594;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033047|UniProtKB=Q0IGX4 Q0IGX4 Dmel\CG7882 PTHR23503:SF127 SOLUTE CARRIER FAMILY 2 FI08437P-RELATED sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;carbohydrate transmembrane transport#GO:0034219;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transport#GO:0008643 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034729|UniProtKB=Q9W251 Q9W251 Dmel\CG10344 PTHR22883:SF414 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC24-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038126|UniProtKB=Q9VFY2 Q9VFY2 Dmel\CG8483 PTHR10334:SF498 CYSTEINE-RICH SECRETORY PROTEIN-RELATED LD39025P defense/immunity protein#PC00090 DROME|FlyBase=FBgn0265356|UniProtKB=B7YZK8 B7YZK8 tn PTHR24104:SF47 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED THIN, ISOFORM C ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0029993|UniProtKB=Q9W3L0 Q9W3L0 Dmel\CG1571 PTHR12442:SF7 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003 axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;outer dynein arm#GO:0036157;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0032394|UniProtKB=Q9VKD2 Q9VKD2 Hacd1 PTHR11035:SF3 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydratase#PC00091 DROME|FlyBase=FBgn0063492|UniProtKB=A1ZB73 A1ZB73 GstE8 PTHR43969:SF8 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE E13, ISOFORM A-RELATED glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0031829|UniProtKB=Q9VMC0 Q9VMC0 IFT52 PTHR12969:SF7 NGD5/OSM-6/IFT52 INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cilium assembly#GO:0060271;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0032129|UniProtKB=Q7JV09 Q7JV09 jp PTHR23085:SF16 GH28348P GH28348P protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 DROME|FlyBase=FBgn0034795|UniProtKB=Q9W1X7 Q9W1X7 MED23 PTHR12691:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 general transcription factor#PC00259 DROME|FlyBase=FBgn0261599|UniProtKB=Q9VH69 Q9VH69 RpS29 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN US14 zinc ion binding#GO:0008270;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0037637|UniProtKB=Q9VHK6 Q9VHK6 IscU PTHR10093:SF8 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME ISCU transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;metal ion binding#GO:0046872;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 chaperone#PC00072 DROME|FlyBase=FBgn0031715|UniProtKB=Q9VMQ3 Q9VMQ3 tomb PTHR12446:SF34 TESMIN/TSO1-RELATED PROTEIN LIN-54 HOMOLOG-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0027592|UniProtKB=Q9Y149 Q9Y149 MED15 PTHR31804:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0039396|UniProtKB=Q868T3 Q868T3 CCAP-R PTHR24224:SF38 CARDIOACCELERATORY PEPTIDE RECEPTOR-RELATED CARDIOACCELERATORY PEPTIDE RECEPTOR-RELATED neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0000557|UniProtKB=P05303 P05303 eEF1alpha2 PTHR23115:SF170 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 2 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 translation factor#PC00223 DROME|FlyBase=FBgn0262582|UniProtKB=Q9U1H0 Q9U1H0 cic PTHR13059:SF13 HMG-BOX TRANSCRIPTION FACTOR BBX PROTEIN CAPICUA HOMOLOG transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0035941|UniProtKB=Q9VSR6 Q9VSR6 Dmel\CG13313 PTHR33236:SF14 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0082582|UniProtKB=A0A0B4K6N4 A0A0B4K6N4 tmod PTHR10901:SF6 TROPOMODULIN TROPOMODULIN, ISOFORM N protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 developmental process#GO:0032502;muscle contraction#GO:0006936;cellular developmental process#GO:0048869;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468 contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0003248|UniProtKB=P08099 P08099 Rh2 PTHR45695:SF43 LEUCOKININ RECEPTOR-RELATED OPSIN RH2 transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 DROME|FlyBase=FBgn0259705|UniProtKB=Q9VDZ5 Q9VDZ5 CG5558 PTHR31792:SF3 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 DROME|FlyBase=FBgn0042118|UniProtKB=Q9I7C6 Q9I7C6 Cpr65Ax1 PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0013953|UniProtKB=Q9VC29 Q9VC29 Esp PTHR11814:SF187 SULFATE TRANSPORTER EPIDERMAL STRIPES AND PATCHES, ISOFORM A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0026196|UniProtKB=Q9VM69 Q9VM69 nop5 PTHR10894:SF1 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 58 RNA binding#GO:0003723;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0019982|UniProtKB=Q94529 Q94529 Gs1l PTHR18901:SF48 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0261552|UniProtKB=A0A0B4KGY6 A0A0B4KGY6 ps PTHR10288:SF339 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN PASILLA binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of mRNA metabolic process#GO:1903311;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0004876|UniProtKB=Q9VE06 Q9VE06 cdi PTHR46485:SF5 LIM DOMAIN KINASE 1 DUAL-SPECIFICITY KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0015001|UniProtKB=P52905 P52905 iotaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0053094|UniProtKB=A0A0B4KH28 A0A0B4KH28 Synd PTHR23065:SF11 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 SYNDAPIN, ISOFORM C lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 organelle organization#GO:0006996;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;biological regulation#GO:0065007;regulation of endocytosis#GO:0030100;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;regulation of transport#GO:0051049 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0030696|UniProtKB=Q9VXN8 Q9VXN8 Dmel\CG8509 PTHR10012:SF0 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR catalytic activity, acting on a protein#GO:0140096;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase activator activity#GO:0019211;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;enzyme activator activity#GO:0008047;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;cis-trans isomerase activity#GO:0016859;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888 cell cycle process#GO:0022402;cellular process#GO:0009987;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphatase activator#PC00182 DROME|FlyBase=FBgn0036849|UniProtKB=Q9VVW9 Q9VVW9 Dmel\CG14079 PTHR16435:SF6 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 IP09370P DROME|FlyBase=FBgn0039856|UniProtKB=Q9V9W4 Q9V9W4 Dmel\CG1774 PTHR12655:SF10 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 DROME|FlyBase=FBgn0024943|UniProtKB=Q9W3E2 Q9W3E2 PIP82 PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED ACTIN NUCLEATION-PROMOTING FACTOR WAS-RELATED binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267 regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0011272|UniProtKB=P41126 P41126 RpL13 PTHR11722:SF0 60S RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN EL13 structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 DROME|FlyBase=FBgn0037689|UniProtKB=Q8MRQ4 Q8MRQ4 CG8135 PTHR21355:SF0 G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 LMBR1 DOMAIN-CONTAINING PROTEIN 2 HOMOLOG membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0287589|UniProtKB=A0A6H2EGA2 A0A6H2EGA2 Dmel\CG46459 PTHR34260:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0002521|UniProtKB=Q8ST83 Q8ST83 pho PTHR14003:SF37 TRANSCRIPTIONAL REPRESSOR PROTEIN YY YY2 TRANSCRIPTION FACTOR RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 nucleus#GO:0005634;chromatin#GO:0000785;PcG protein complex#GO:0031519;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0027539|UniProtKB=Q9VC35 Q9VC35 lili PTHR12625:SF0 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR PROTEIN LILIPOD molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0023213|UniProtKB=A8DZ29 A8DZ29 eIF4G1 PTHR23253:SF78 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 translation initiation factor#PC00224 DROME|FlyBase=FBgn0027872|UniProtKB=Q9U9P7 Q9U9P7 rdgBbeta PTHR10658:SF54 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CYTOPLASMIC PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 binding#GO:0005488;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;transporter activity#GO:0005215;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303;cation binding#GO:0043169;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylcholine binding#GO:0031210;phosphatidylinositol transfer activity#GO:0008526 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0028868|UniProtKB=Q9V3Q1 Q9V3Q1 DmDM19DC4Z PTHR45644:SF88 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED FI08533P-RELATED cellular process#GO:0009987;establishment of protein localization#GO:0045184;localization within membrane#GO:0051668;establishment of protein localization to membrane#GO:0090150;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 DROME|FlyBase=FBgn0000591|UniProtKB=P13098 P13098 E(spl)m8-HLH PTHR10985:SF12 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED ENHANCER OF SPLIT M3 PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 pattern specification process#GO:0007389;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 DROME|FlyBase=FBgn0031871|UniProtKB=Q9VM65 Q9VM65 Fgop2 PTHR12186:SF2 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 HOMOLOG DROME|FlyBase=FBgn0037770|UniProtKB=Q9VH48 Q9VH48 Art4 PTHR11006:SF10 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARMER-RELATED histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0263050|UniProtKB=Q9VIE9 Q9VIE9 CG9243 PTHR10185:SF17 PHOSPHOLIPASE D - RELATED GM01519P-RELATED phospholipase#PC00186 DROME|FlyBase=FBgn0030735|UniProtKB=Q7YU03 Q7YU03 Dmel\CG3632 PTHR10807:SF75 MYOTUBULARIN-RELATED LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG hydrolase activity#GO:0016787;protein binding#GO:0005515;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488;protein phosphatase binding#GO:0019903;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 DROME|FlyBase=FBgn0042094|UniProtKB=Q9VGU6 Q9VGU6 Ak3 PTHR23359:SF242 NUCLEOTIDE KINASE GTP:AMP PHOSPHOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 DROME|FlyBase=FBgn0029966|UniProtKB=Q9W3P2 Q9W3P2 Ir7c PTHR42643:SF52 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 11A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0020377|UniProtKB=A1Z8V0 A1Z8V0 Sr-CII PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED DROME|FlyBase=FBgn0040629|UniProtKB=Q9V9Y6 Q9V9Y6 CAH5 PTHR18952:SF137 CARBONIC ANHYDRASE CARBONIC ANHYDRASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0035076|UniProtKB=Q9W0Z1 Q9W0Z1 Ance-5 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 DROME|FlyBase=FBgn0039155|UniProtKB=Q9VCC7 Q9VCC7 Kal1 PTHR14131:SF5 ANOSMIN ANOSMIN-1 neurogenesis#GO:0022008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;generation of neurons#GO:0048699;developmental process#GO:0032502;neuron differentiation#GO:0030182;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;cellular process#GO:0009987 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0036334|UniProtKB=Q9VU35 Q9VU35 Dmel\CG11267 PTHR10772:SF67 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL ion binding#GO:0043167;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 chaperonin#PC00073 DROME|FlyBase=FBgn0010409|UniProtKB=P41093 P41093 RpL18A PTHR10052:SF1 60S RIBOSOMAL PROTEIN L18A LARGE RIBOSOMAL SUBUNIT PROTEIN EL20 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 DROME|FlyBase=FBgn0034265|UniProtKB=Q7JR96 Q7JR96 Snx16 PTHR22999:SF43 PX SERINE/THREONINE KINASE PXK SORTING NEXIN-16 ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;binding#GO:0005488 endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;macromolecule metabolic process#GO:0043170;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;endosome to lysosome transport#GO:0008333;metabolic process#GO:0008152;lysosomal transport#GO:0007041;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;establishment of localization in cell#GO:0051649 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 DROME|FlyBase=FBgn0031266|UniProtKB=Q9VPR5 Q9VPR5 Sf3b1 PTHR12097:SF0 SPLICING FACTOR 3B, SUBUNIT 1-RELATED SPLICING FACTOR 3B SUBUNIT 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933 U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0264299|UniProtKB=A0A0B4LGE9 A0A0B4LGE9 CG13569 PTHR10334:SF613 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0027080|UniProtKB=Q9VV60 Q9VV60 TyrRS PTHR11586:SF43 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER TYROSINE--TRNA LIGASE, CYTOPLASMIC catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263 DROME|FlyBase=FBgn0060296|UniProtKB=Q9W0Y6 Q9W0Y6 pain PTHR47143:SF4 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;transport#GO:0006810 membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transporter complex#GO:1990351 ion channel#PC00133 DROME|FlyBase=FBgn0037579|UniProtKB=Q9VHR9 Q9VHR9 COX7AL PTHR10510:SF13 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A-LIKE-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175 DROME|FlyBase=FBgn0284220|UniProtKB=P15348 P15348 Top2 PTHR10169:SF38 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543 nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;organelle fission#GO:0048285;primary metabolic process#GO:0044238;sister chromatid segregation#GO:0000819;meiotic cell cycle process#GO:1903046;nucleic acid metabolic process#GO:0090304;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle#GO:0007049;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;homologous recombination#GO:0035825;reproductive process#GO:0022414;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;organelle organization#GO:0006996;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 DROME|FlyBase=FBgn0027582|UniProtKB=Q9VKJ6 Q9VKJ6 Dmel\CG6230 PTHR45630:SF7 CATION-TRANSPORTING ATPASE-RELATED FI03653P protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 primary active transporter#PC00068 DROME|FlyBase=FBgn0001142|UniProtKB=P20477 P20477 Gs1 PTHR20852:SF44 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE 1, MITOCHONDRIAL ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 DROME|FlyBase=FBgn0039510|UniProtKB=Q0KI05 Q0KI05 Dmel\CG3339 PTHR10676:SF36 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN AT 93AB, ISOFORM C macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule motor activity#GO:0003777;protein binding#GO:0005515 cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;microtubule-based movement#GO:0007018;cell motility#GO:0048870 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;dynein complex#GO:0030286;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0050360|UniProtKB=A1Z7F1 A1Z7F1 Mal-A6 PTHR10357:SF234 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A2-RELATED metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;carbohydrate metabolic process#GO:0005975 amylase#PC00048;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0036369|UniProtKB=M9PI51 M9PI51 Dmel\CG10089 PTHR45948:SF2 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED DUAL SPECIFICITY PROTEIN PHOSPHATASE 15 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 DROME|FlyBase=FBgn0050364|UniProtKB=A1Z7D7 A1Z7D7 hubl PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0002466|UniProtKB=M9PI41 M9PI41 sti PTHR22988:SF82 MYOTONIC DYSTROPHY S/T KINASE-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of biological quality#GO:0065008;cytoskeleton-dependent cytokinesis#GO:0061640;regulation of actin filament length#GO:0030832;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;actomyosin structure organization#GO:0031032;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;cytoskeleton organization#GO:0007010;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;organelle organization#GO:0006996 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0039280|UniProtKB=Q9VBX2 Q9VBX2 Mocs2B PTHR23404:SF2 MOLYBDOPTERIN SYNTHASE RELATED MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028499|UniProtKB=Q9VEB8 Q9VEB8 Dmel\CG7985 PTHR21040:SF8 BCDNA.GH04120 HEXOSAMINIDASE D catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 DROME|FlyBase=FBgn0035452|UniProtKB=B7Z0B2 B7Z0B2 AAF47782 PTHR19143:SF470 FIBRINOGEN/TENASCIN/ANGIOPOEITIN GH05177P-RELATED cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0034392|UniProtKB=A1ZBD9 A1ZBD9 MFS15 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034458|UniProtKB=A1ZBM9 A1ZBM9 Ir56d PTHR42643:SF39 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 56A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0039875|UniProtKB=Q95SP2 Q95SP2 sip3 PTHR22763:SF196 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to endoplasmic reticulum stress#GO:0034976 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0260003|UniProtKB=Q9VDW6 Q9VDW6 Dys PTHR11915:SF455 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ, SARCOMERIC-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization#GO:0016043;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029 cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;Z disc#GO:0030018;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;membrane#GO:0016020;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;I band#GO:0031674;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 DROME|FlyBase=FBgn0034356|UniProtKB=Q7JXB5 Q7JXB5 Pepck2 PTHR11561:SF0 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP] transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;lyase activity#GO:0016829;metal ion binding#GO:0046872;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 chemical homeostasis#GO:0048878;cellular response to glucose stimulus#GO:0071333;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;alcohol metabolic process#GO:0006066;glucose homeostasis#GO:0042593;glucose metabolic process#GO:0006006;gluconeogenesis#GO:0006094;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to stress#GO:0006950;carbohydrate biosynthetic process#GO:0016051;response to chemical#GO:0042221;response to lipid#GO:0033993;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;response to monosaccharide#GO:0034284;cellular response to chemical stimulus#GO:0070887;intracellular glucose homeostasis#GO:0001678;response to carbohydrate#GO:0009743;carbohydrate homeostasis#GO:0033500;response to hexose#GO:0009746;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;small molecule biosynthetic process#GO:0044283;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;response to nutrient levels#GO:0031667;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;response to glucose#GO:0009749;hexose biosynthetic process#GO:0019319;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 DROME|FlyBase=FBgn0031181|UniProtKB=Q9VRI8 Q9VRI8 Ir20a PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0052412|UniProtKB=Q9VRQ9 Q9VRQ9 QC PTHR12283:SF5 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;zinc ion binding#GO:0008270;metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;acyltransferase activity#GO:0016746;transition metal ion binding#GO:0046914 transferase#PC00220 DROME|FlyBase=FBgn0015509|UniProtKB=Q24311 Q24311 Cul1 PTHR11932:SF168 CULLIN CULLIN-1 structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Cul-1#P01239 DROME|FlyBase=FBgn0035162|UniProtKB=Q9W0M7 Q9W0M7 Sf3b3 PTHR10644:SF1 DNA REPAIR/RNA PROCESSING CPSF FAMILY SPLICING FACTOR 3B SUBUNIT 3 snRNA binding#GO:0017069;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0051477|UniProtKB=Q9VH24 Q9VH24 ATPsynepsilonL PTHR12448:SF0 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT EPSILON, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 ATP synthase#PC00002 DROME|FlyBase=FBgn0288888|UniProtKB=P41894 P41894 tx PTHR19290:SF147 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED HELIX-LOOP-HELIX PROTEIN DELILAH double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0025800|UniProtKB=O96660 O96660 Smox PTHR13703:SF25 SMAD SMAD FAMILY MEMBER 2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to growth factor stimulus#GO:0071363;activin receptor signaling pathway#GO:0032924;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;positive regulation of macromolecule metabolic process#GO:0010604;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 ALP23B signaling pathway#P06209>SMOX#P06224;TGF-beta signaling pathway#P00052>RSmads#P01292;BMP/activin signaling pathway-drosophila#P06211>R-Smad#P06245;Activin beta signaling pathway#P06210>SMOX#P06236;MYO signaling pathway#P06215>SMOX#P06314 DROME|FlyBase=FBgn0050196|UniProtKB=Q9W222 Q9W222 CG13514 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED transition metal ion binding#GO:0046914;ion binding#GO:0043167;zinc ion binding#GO:0008270;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0004516|UniProtKB=P20228 P20228 Gad1 PTHR45677:SF10 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 DROME|FlyBase=FBgn0035670|UniProtKB=Q9VRT2 Q9VRT2 Dmel\CG10472 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0264253|UniProtKB=Q7KT95 Q7KT95 Send2 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0052095|UniProtKB=Q95U65 Q95U65 BcDNA:GH03217 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0004378|UniProtKB=P46863 P46863 Klp61F PTHR47970:SF41 KINESIN-LIKE PROTEIN KIF11 KINESIN FAMILY MEMBER 11 polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;plus-end-directed microtubule motor activity#GO:0008574;microtubule motor activity#GO:0003777;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cellular component assembly#GO:0022607;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;nuclear division#GO:0000280;organelle assembly#GO:0070925 microtubule#GO:0005874;spindle microtubule#GO:0005876;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0051121|UniProtKB=Q0KI14 Q0KI14 CG18633 PTHR48041:SF89 ABC TRANSPORTER G FAMILY MEMBER 28 FI03229P transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0051007|UniProtKB=Q4V6F6 Q4V6F6 Dmel\CG31007 PTHR13523:SF2 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 mitochondrion#GO:0005739;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0001150|UniProtKB=P39572 P39572 gt PTHR11988:SF57 THYROTROPH EMBRYONIC FACTOR RELATED PROTEIN GIANT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0040296|UniProtKB=Q9VUI5 Q9VUI5 Ocho PTHR12254:SF0 ENHANCER OF SPLIT MALPHA PROTEIN BARBU-RELATED DROME|FlyBase=FBgn0000018|UniProtKB=Q9VKM4 Q9VKM4 ao PTHR13374:SF3 DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG DET1 HOMOLOG ubiquitin protein ligase binding#GO:0031625;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like protein ligase binding#GO:0044389;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;primary metabolic process#GO:0044238;protein modification process#GO:0036211;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0027111|UniProtKB=Q9W0S5 Q9W0S5 miple1 PTHR21050:SF1 MIDKINE AND PLEIOTROPHIN 1, ISOFORM A-RELATED MIDKINE AND PLEIOTROPHIN 1, ISOFORM A-RELATED heparin binding#GO:0008201;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;tissue morphogenesis#GO:0048729;mesoderm development#GO:0007498;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;mesoderm morphogenesis#GO:0048332;multicellular organismal process#GO:0032501;tissue development#GO:0009888 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0020407|UniProtKB=Q9VEX5 Q9VEX5 Asun PTHR12955:SF1 SARCOMA ANTIGEN NY-SAR-95-RELATED INTEGRATOR COMPLEX SUBUNIT 13 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;centrosome localization#GO:0051642;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0036058|UniProtKB=Q9VT69 Q9VT69 Dmel\CG6707 PTHR21014:SF6 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid modification#GO:0030258;dephosphorylation#GO:0016311;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 DROME|FlyBase=FBgn0035590|UniProtKB=Q9VRJ6 Q9VRJ6 Tcs5 PTHR12209:SF0 NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE EKC_KEOPS COMPLEX SUBUNIT TP53RK kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0085380|UniProtKB=M9PCK0 M9PCK0 dcma PTHR21029:SF21 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG DECIMA, ISOFORM D cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 neuron projection#GO:0043005;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0001989|UniProtKB=Q9V3W2 Q9V3W2 ND-B17 PTHR21106:SF2 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 GM23292P cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0261928|UniProtKB=A0A0B4LH08 A0A0B4LH08 blobby PTHR22957:SF168 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0010359|UniProtKB=C0HKA3 C0HKA3 gammaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0261793|UniProtKB=Q07DP5 Q07DP5 Trf2 PTHR10126:SF69 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 1 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription regulation#P00023>TBP#P00670 DROME|FlyBase=FBgn0033550|UniProtKB=Q7JV61 Q7JV61 Dmel\CG12341 PTHR22779:SF6 SD17342P SD17342P DROME|FlyBase=FBgn0037831|UniProtKB=Q8INL2 Q8INL2 Cap-H2 PTHR14324:SF3 CONDENSIN-2 COMPLEX SUBUNIT H2 CONDENSIN-2 COMPLEX SUBUNIT H2 binding#GO:0005488;chromatin binding#GO:0003682 chromosome separation#GO:0051304;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome segregation#GO:0007059;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;organelle fission#GO:0048285;chromosome condensation#GO:0030261;nuclear division#GO:0000280;sexual reproduction#GO:0019953;mitotic sister chromatid separation#GO:0051306;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;sister chromatid segregation#GO:0000819;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensin complex#GO:0000796;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 DROME|FlyBase=FBgn0035534|UniProtKB=Q9VZD5 Q9VZD5 mRpS6 PTHR21011:SF17 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0051365|UniProtKB=Q8T051 Q8T051 CG4639 PTHR24393:SF183 ZINC FINGER PROTEIN LD28458P-RELATED transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0025366|UniProtKB=O76994 O76994 Ip259 PTHR12642:SF0 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0037105|UniProtKB=Q9VP10 Q9VP10 S1P PTHR43806:SF7 PEPTIDASE S8 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 serine protease#PC00203 DROME|FlyBase=FBgn0064225|UniProtKB=Q9W5R8 Q9W5R8 RpL5 PTHR23410:SF12 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;ribosomal large subunit assembly#GO:0000027;biological regulation#GO:0065007;organelle assembly#GO:0070925;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;protein-RNA complex assembly#GO:0022618;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;positive regulation of protein metabolic process#GO:0051247;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 DROME|FlyBase=FBgn0030104|UniProtKB=Q9W371 Q9W371 Dmel\CG15368 PTHR10634:SF149 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0037736|UniProtKB=Q9VH85 Q9VH85 side-VII PTHR23278:SF25 SIDESTEP PROTEIN GH14967P immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0038001|UniProtKB=Q9VGC0 Q9VGC0 SP149 PTHR24256:SF562 TRYPTASE-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN-RELATED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0026778|UniProtKB=Q9VQD4 Q9VQD4 Rad1 PTHR10870:SF0 CELL CYCLE CHECKPOINT PROTEIN RAD1 CELL CYCLE CHECKPOINT PROTEIN RAD1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 negative regulation of cell cycle#GO:0045786;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA integrity checkpoint signaling#GO:0031570;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716 condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 DROME|FlyBase=FBgn0036740|UniProtKB=Q9VVI9 Q9VVI9 Vps60 PTHR22761:SF12 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 cellular component organization#GO:0016043;membrane assembly#GO:0071709;late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;localization#GO:0051179;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;nuclear membrane organization#GO:0071763;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;endosomal transport#GO:0016197 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0032136|UniProtKB=Q7KTG2 Q7KTG2 Apoltp PTHR23345:SF38 VITELLOGENIN-RELATED APOLIPOPROTEIN LIPID TRANSFER PARTICLE molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 storage protein#PC00210 DROME|FlyBase=FBgn0041096|UniProtKB=Q9VTS9 Q9VTS9 rols PTHR24166:SF55 ROLLING PEBBLES, ISOFORM B ROLLING PEBBLES, ISOFORM B scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0003449|UniProtKB=P43332 P43332 snf PTHR10501:SF13 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;U1 snRNP#GO:0005685;organelle#GO:0043226 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 mRNA splicing#P00058>U2#P01478;mRNA splicing#P00058>U1#P01479 DROME|FlyBase=FBgn0035423|UniProtKB=Q9VZS3 Q9VZS3 eIF1 PTHR10388:SF87 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR EIF1 translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224 DROME|FlyBase=FBgn0033020|UniProtKB=Q8T4H8 Q8T4H8 COX4L PTHR10707:SF10 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;transporter complex#GO:1990351;organelle membrane#GO:0031090 oxidoreductase#PC00176;oxidase#PC00175 DROME|FlyBase=FBgn0026570|UniProtKB=Q9W047 Q9W047 LD30049 PTHR43329:SF4 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 DROME|FlyBase=FBgn0036059|UniProtKB=Q9VT70 Q9VT70 nudE PTHR10921:SF4 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 establishment of organelle localization#GO:0051656;centrosome localization#GO:0051642;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;protein polymerization#GO:0051258;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular localization#GO:0051641;spindle localization#GO:0051653;establishment or maintenance of cell polarity#GO:0007163;nuclear division#GO:0000280;microtubule-based transport#GO:0099111;cellular component assembly#GO:0022607;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;organelle transport along microtubule#GO:0072384;chromosome localization#GO:0050000;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;protein-containing complex organization#GO:0043933;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;establishment of cell polarity#GO:0030010;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;supramolecular fiber organization#GO:0097435;organelle localization#GO:0051640;cytoskeleton-dependent intracellular transport#GO:0030705;cell migration#GO:0016477;microtubule polymerization or depolymerization#GO:0031109;vesicle localization#GO:0051648;establishment of spindle localization#GO:0051293;establishment of mitotic spindle orientation#GO:0000132;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;mitotic cell cycle process#GO:1903047;microtubule polymerization#GO:0046785;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810 organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793 DROME|FlyBase=FBgn0038581|UniProtKB=Q9VEB7 Q9VEB7 Dmel\CG14314 PTHR11012:SF60 PROTEIN KINASE-LIKE DOMAIN-CONTAINING AT04491P DROME|FlyBase=FBgn0010355|UniProtKB=P51123 P51123 Taf1 PTHR13900:SF0 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1 protein binding#GO:0005515;binding#GO:0005488;transcription factor binding#GO:0008134 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0061515|UniProtKB=Q9VUB8 Q9VUB8 endos PTHR10358:SF6 ENDOSULFINE ENDOSULFINE, ISOFORM A molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053922|UniProtKB=Q4ABI3 Q4ABI3 Dmel\CG33922 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0033464|UniProtKB=Q7K3T3 Q7K3T3 Dmel\CG1441 PTHR11011:SF61 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0051200|UniProtKB=Q95SN8 Q95SN8 CG17837 PTHR24260:SF87 AT07769P-RELATED GH08193P-RELATED DROME|FlyBase=FBgn0032971|UniProtKB=Q9V9P3 Q9V9P3 ttm3 PTHR12210:SF3 DULLARD PROTEIN PHOSPHATASE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 protein phosphatase#PC00195 DROME|FlyBase=FBgn0037408|UniProtKB=Q9VNM1 Q9VNM1 NPFR PTHR24235:SF30 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE F RECEPTOR neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0029957|UniProtKB=Q9W3Q2 Q9W3Q2 Dmel\CG12155 PTHR23009:SF2 FAMILY NOT NAMED HISTIDINE-RICH CARBOXYL TERMINUS PROTEIN 1 DROME|FlyBase=FBgn0004045|UniProtKB=P02843 P02843 Yp1 PTHR11610:SF149 LIPASE FI01450P-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0001257|UniProtKB=Q09024 Q09024 ImpL2 PTHR10075:SF109 BASIGIN RELATED NEURAL_ECTODERMAL DEVELOPMENT FACTOR IMP-L2 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0025693|UniProtKB=Q8T0G1 Q8T0G1 ZnT41F PTHR11562:SF17 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER LD05335P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075 zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;transport#GO:0006810;zinc ion transmembrane transport#GO:0071577 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0038545|UniProtKB=Q9VEF6 Q9VEF6 pasi1 PTHR36694:SF13 PASIFLORA 1, ISOFORM A-RELATED PASIFLORA 1, ISOFORM A cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;biological regulation#GO:0065007;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;regulation of anatomical structure size#GO:0090066;neurogenesis#GO:0022008;gliogenesis#GO:0042063;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell development#GO:0048468;cell junction organization#GO:0034330;central nervous system development#GO:0007417;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0002643|UniProtKB=P21519 P21519 mam PTHR16431:SF1 NEUROGENIC PROTEIN MASTERMIND NEUROGENIC PROTEIN MASTERMIND kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;kinetochore organization#GO:0051383;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;chromatin organization#GO:0006325;cellular component assembly#GO:0022607 chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0038681|UniProtKB=Q9VE00 Q9VE00 Cyp12a4 PTHR24305:SF238 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0022224|UniProtKB=Q9V998 Q9V998 ubl PTHR13042:SF0 UBIQUITIN-LIKE PROTEIN 5 UBIQUITIN-LIKE PROTEIN 5 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0035902|UniProtKB=Q9VSL0 Q9VSL0 Dmel\CG6683 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0266409|UniProtKB=A0A0B4LHK8 A0A0B4LHK8 CG6982 PTHR14399:SF5 P53-INDUCED PROTEIN RELATED TRANSMEMBRANE PROTEIN 47 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 DROME|FlyBase=FBgn0010247|UniProtKB=P35875 P35875 Parp1 PTHR10459:SF118 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 2 pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 DROME|FlyBase=FBgn0036133|UniProtKB=Q9VTF5 Q9VTF5 emei PTHR13624:SF6 RE42071P EMEI DROME|FlyBase=FBgn0038975|UniProtKB=Q3KN41 Q3KN41 Nrx-1 PTHR15036:SF89 PIKACHURIN-LIKE PROTEIN NEUREXIN 1 molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023;signaling receptor binding#GO:0005102;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;signal transduction#GO:0007165;postsynaptic density assembly#GO:0097107;cellular process#GO:0009987;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;synapse assembly#GO:0007416;signaling#GO:0023052;excitatory synapse assembly#GO:1904861;animal gross anatomical part developmental process#GO:0160108;postsynaptic density organization#GO:0097106;nervous system process#GO:0050877;macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;developmental process#GO:0032502;system process#GO:0003008;intracellular protein localization#GO:0008104;cellular response to stimulus#GO:0051716;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;postsynapse organization#GO:0099173;organelle assembly#GO:0070925;protein localization to cell junction#GO:1902414;cognition#GO:0050890;synapse organization#GO:0050808;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;postsynaptic specialization organization#GO:0099084 presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;presynaptic active zone membrane#GO:0048787;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0030984|UniProtKB=Q9VWM1 Q9VWM1 tgy PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;galactosyltransferase activity#GO:0008378 transferase#PC00220 DROME|FlyBase=FBgn0039955|UniProtKB=Q7PLP5 Q7PLP5 BEST:GM10035 PTHR24198:SF191 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN RABANKYRIN-5-LIKE non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0038049|UniProtKB=Q9VG69 Q9VG69 Srlp PTHR43802:SF1 ENOYL-COA HYDRATASE IP11341P-RELATED hydratase#PC00120;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039052|UniProtKB=Q9VCQ9 Q9VCQ9 Dmel\CG6733 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 DROME|FlyBase=FBgn0034214|UniProtKB=Q7K4W1 Q7K4W1 CG6550 PTHR11918:SF45 RADICAL SAM PROTEINS THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0011278|UniProtKB=Q7KS77 Q7KS77 lbe PTHR24336:SF8 TRANSCRIPTION FACTOR LBX LADYBIRD EARLY-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0028424|UniProtKB=Q7K0P0 Q7K0P0 JhI-26 PTHR11012:SF8 PROTEIN KINASE-LIKE DOMAIN-CONTAINING JUVENILE HORMONE-INDUCIBLE PROTEIN 26 DROME|FlyBase=FBgn0031765|UniProtKB=X2JDC2 X2JDC2 Dmel\CG9109 PTHR10811:SF110 FRINGE-RELATED BETA-1,3-GLUCOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0027951|UniProtKB=A0A0B4KG70 A0A0B4KG70 MTA1-like PTHR10865:SF29 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA3 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;histone deacetylase binding#GO:0042826;transcription coactivator activity#GO:0003713;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;protein binding#GO:0005515 negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 p53 pathway#P00059>MTA2#P04615 DROME|FlyBase=FBgn0024733|UniProtKB=O61231 O61231 RpL10 PTHR11726:SF10 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0031883|UniProtKB=Q9VM49 Q9VM49 Caper PTHR48036:SF6 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA-BINDING MOTIF PROTEIN 39A-RELATED binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0039836|UniProtKB=Q9V9Z0 Q9V9Z0 Dmel\CG1750 PTHR11138:SF5 METHIONYL-TRNA FORMYLTRANSFERASE METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032330|UniProtKB=Q9VKL0 Q9VKL0 Samuel PTHR12247:SF138 POLYCOMB GROUP PROTEIN L(3)MBT INTERACTOR IN OVARIAN SOMATIC CELLS, ISOFORM A-RELATED histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0034535|UniProtKB=Q4QQ12 Q4QQ12 Immp2 PTHR46041:SF2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 endopeptidase complex#GO:1905369;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190 DROME|FlyBase=FBgn0036219|UniProtKB=Q9VTQ3 Q9VTQ3 CCDC151 PTHR46518:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 151 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3 plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cilium movement#GO:0003341;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0039116|UniProtKB=Q9VCH9 Q9VCH9 Dmel\CG10375 PTHR15606:SF4 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 8 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|FlyBase=FBgn0262733|UniProtKB=P00528 P00528 Src64B PTHR24418:SF447 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRC64B transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;signaling receptor binding#GO:0005102;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940;Angiogenesis#P00005>Src#P00184 DROME|FlyBase=FBgn0033194|UniProtKB=A1Z713 A1Z713 Vps13 PTHR16166:SF147 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13 phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 lipid localization#GO:0010876;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;catabolic process#GO:0009056;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;autophagy#GO:0006914;lipid transport#GO:0006869;macroautophagy#GO:0016236;membrane organization#GO:0061024;mitochondrion organization#GO:0007005 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;mitochondrion#GO:0005739;vesicle#GO:0031982;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0037009|UniProtKB=Q9VPD4 Q9VPD4 Dmel\CG5104 PTHR23137:SF6 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN DROME|FlyBase=FBgn0026439|UniProtKB=A0A6H2EJK0 A0A6H2EJK0 Eaat1 PTHR11958:SF63 SODIUM/DICARBOXYLATE SYMPORTER-RELATED AMINO ACID TRANSPORTER amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283 L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization#GO:0051234;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;acidic amino acid transport#GO:0015800;carboxylic acid transport#GO:0046942;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;L-glutamate import#GO:0051938 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 DROME|FlyBase=FBgn0036975|UniProtKB=Q9VPH6 Q9VPH6 Dmel\CG5618 PTHR45677:SF13 GLUTAMATE DECARBOXYLASE-RELATED LP10922P catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 DROME|FlyBase=FBgn0039193|UniProtKB=Q9VC83 Q9VC83 Dmel\CG13613 PTHR21398:SF6 AGAP007094-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0005536|UniProtKB=M9NEB2 M9NEB2 Mbs PTHR24179:SF21 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12B protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0035430|UniProtKB=Q9VZR6 Q9VZR6 Dmel\CG12009 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0031264|UniProtKB=Q9VPR2 Q9VPR2 uncNacbeta PTHR10351:SF23 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0034181|UniProtKB=Q7K581 Q7K581 Paip1 PTHR23254:SF15 EIF4G DOMAIN PROTEIN POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1 translation regulator activity#GO:0045182 regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0261802|UniProtKB=M9PDE6 M9PDE6 CG6448 PTHR21517:SF3 APICAL JUNCTION COMPONENT 1 HOMOLOG APICAL JUNCTION COMPONENT 1 HOMOLOG cellular process#GO:0009987;cell-cell junction organization#GO:0045216;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;cell junction#GO:0030054;apical junction complex#GO:0043296 DROME|FlyBase=FBgn0051146|UniProtKB=Q9VIC7 Q9VIC7 Nlg1 PTHR43903:SF23 NEUROLIGIN NEUROLIGIN 1, ISOFORM D signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular localization#GO:0051641;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;synapse assembly#GO:0007416;endocytosis#GO:0006897;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;nervous system development#GO:0007399;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;membrane organization#GO:0061024;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465 synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell surface#GO:0009986 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0284245|UniProtKB=P08736 P08736 eEF1alpha1 PTHR23115:SF236 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412 translation factor#PC00223 DROME|FlyBase=FBgn0040259|UniProtKB=Q9VGT3 Q9VGT3 Ugt302C1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 DROME|FlyBase=FBgn0053658|UniProtKB=Q4AB23 Q4AB23 BP1056 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0004903|UniProtKB=Q02926 Q02926 Rb97D PTHR48038:SF6 RIBONUCLEOPROTEIN RB97D RIBONUCLEOPROTEIN RB97D DROME|FlyBase=FBgn0035866|UniProtKB=Q9VSG8 Q9VSG8 Arl5 PTHR11711:SF31 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE 5 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein#PC00020 DROME|FlyBase=FBgn0266363|UniProtKB=X2JA66 X2JA66 Dmel\CG45011 PTHR21131:SF0 SERINE-TYPE ENDOPEPTIDASE INHIBITOR GEO10195P1-RELATED protease inhibitor#PC00191 DROME|FlyBase=FBgn0035235|UniProtKB=Q9W0D6 Q9W0D6 cg7879 PTHR13976:SF88 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED FI22004P1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030707|UniProtKB=Q9VXL9 Q9VXL9 Lcch-14A PTHR18945:SF920 NEUROTRANSMITTER GATED ION CHANNEL IP12579P cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0263979|UniProtKB=Q24572 Q24572 Caf1-55 PTHR22850:SF221 WD40 REPEAT FAMILY CHROMATIN ASSEMBLY FACTOR 1 P55 SUBUNIT binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;PcG protein complex#GO:0031519;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097 DROME|FlyBase=FBgn0035083|UniProtKB=Q9W0Y1 Q9W0Y1 Tina-1 PTHR12510:SF18 TROPONIN C-AKIN-1 PROTEIN TROPONIN C-AKIN-1 PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DROME|FlyBase=FBgn0032166|UniProtKB=Q7KTG0 Q7KTG0 CG31879 PTHR21228:SF69 FAST LEU-RICH DOMAIN-CONTAINING GH07286P-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;gene expression#GO:0010467;RNA processing#GO:0006396;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233 RNA processing factor#PC00147 DROME|FlyBase=FBgn0039009|UniProtKB=Q9VCV8 Q9VCV8 Dmel\CG13842 PTHR21436:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 DROME|FlyBase=FBgn0036208|UniProtKB=Q9VTN9 Q9VTN9 Gcat PTHR13693:SF105 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transaminase#PC00216 DROME|FlyBase=FBgn0025820|UniProtKB=O96067 O96067 JTBR PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell division#GO:0051301;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic cell cycle process#GO:1903047;cytokinesis#GO:0000910 cytoskeleton#GO:0005856;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0037862|UniProtKB=Q8T4D6 Q8T4D6 mAcon2 PTHR43160:SF3 ACONITATE HYDRATASE B ACONITATE HYDRATASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;iron-sulfur cluster binding#GO:0051536;hydro-lyase activity#GO:0016836;binding#GO:0005488;small molecule binding#GO:0036094;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lyase#PC00144;hydratase#PC00120 TCA cycle#P00051>Aconitase#P01268 DROME|FlyBase=FBgn0039593|UniProtKB=Q9VAU2 Q9VAU2 Sid PTHR13966:SF19 ENDONUCLEASE RELATED DNA_RNA NON-SPECIFIC ENDONUCLEASE DOMAIN-CONTAINING PROTEIN-RELATED DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536 cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0037705|UniProtKB=Q9VHC2 Q9VHC2 mura PTHR46171:SF3 GH10160P GH10160P ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 DROME|FlyBase=FBgn0288834|UniProtKB=Q9VIH1 Q9VIH1 RPA2 PTHR13989:SF16 REPLICATION PROTEIN A-RELATED REPLICATION FACTOR A PROTEIN 2 sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;replisome#GO:0030894;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;chromosome, telomeric region#GO:0000781;protein-containing complex#GO:0032991 DNA replication#P00017>RPA#P00537 DROME|FlyBase=FBgn0033880|UniProtKB=Q4V6B0 Q4V6B0 Dmel\CG6553 PTHR24270:SF62 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED CD320 ANTIGEN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;apolipoprotein#PC00052 DROME|FlyBase=FBgn0260789|UniProtKB=Q9W363 Q9W363 mxc PTHR23202:SF130 WASP INTERACTING PROTEIN-RELATED MULTI SEX COMBS, ISOFORM A-RELATED intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0262736|UniProtKB=P23380 P23380 Vha16-1 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0000097|UniProtKB=Q01842 Q01842 aop PTHR11849:SF201 ETS ETS DNA-BINDING PROTEIN POKKURI DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032125|UniProtKB=Q9VLB1 Q9VLB1 Cpr30B PTHR12236:SF46 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 30B-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0030510|UniProtKB=Q9VYA1 Q9VYA1 Dmel\CG12177 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 DROME|FlyBase=FBgn0030578|UniProtKB=Q9VY20 Q9VY20 Dmel\CG5347 PTHR11224:SF10 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0037857|UniProtKB=Q9VGU3 Q9VGU3 Tengl4 PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097 cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;catabolic process#GO:0009056;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411 organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 Apoptosis signaling pathway#P00006>endoG#P00279 DROME|FlyBase=FBgn0261647|UniProtKB=Q9U4G5 Q9U4G5 Axud1 PTHR13580:SF10 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0010389|UniProtKB=Q07407 Q07407 htl PTHR24416:SF550 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;response to fibroblast growth factor#GO:0071774;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0259676|UniProtKB=Q9VPH2 Q9VPH2 Prim2 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;RNA metabolic process#GO:0016070 DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;replication fork#GO:0005657;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231 primase#PC00189 DNA replication#P00017>Primase#P00528 DROME|FlyBase=FBgn0039627|UniProtKB=Q9VAQ5 Q9VAQ5 CG11837 PTHR11727:SF34 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037140|UniProtKB=Q9VNX2 Q9VNX2 SLC22A PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER FI24011P1-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0032494|UniProtKB=Q9VK12 Q9VK12 Jhbp13 PTHR11008:SF18 PROTEIN TAKEOUT-LIKE PROTEIN BCDNA.GH05536-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0034418|UniProtKB=Q7K4M9 Q7K4M9 anon-EST:fe1H12 PTHR12447:SF31 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 LD31969P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;late endosome#GO:0005770;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051675|UniProtKB=Q8SXV2 Q8SXV2 Dmel\CG31675 PTHR33562:SF18 ATILLA, ISOFORM B-RELATED-RELATED RE19849P-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0051414|UniProtKB=Q8IMY3 Q8IMY3 Gba1b PTHR11069:SF23 GLUCOSYLCERAMIDASE LYSOSOMAL ACID GLUCOSYLCERAMIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;carbohydrate derivative catabolic process#GO:1901136;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672 DROME|FlyBase=FBgn0017457|UniProtKB=Q94535 Q94535 U2af38 PTHR12620:SF8 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT U2 SMALL NUCLEAR RNA AUXILIARY FACTOR 1 RNA binding#GO:0003723;binding#GO:0005488;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0004657|UniProtKB=P11584 P11584 mys PTHR10082:SF60 INTEGRIN BETA SUBUNIT INTEGRIN BETA-PS protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166;cell migration#GO:0016477;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;focal adhesion#GO:0005925 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 DROME|FlyBase=FBgn0038890|UniProtKB=Q0KI33 Q0KI33 sp3 PTHR45662:SF8 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITIDE 4-PHOSPHATASE SAC2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;regulation of transport#GO:0051049;regulation of localization#GO:0032879;lipid modification#GO:0030258;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856 early endosome#GO:0005769;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;clathrin-coated endocytic vesicle#GO:0045334;endoplasmic reticulum#GO:0005783;clathrin-coated vesicle#GO:0030136;cytoplasm#GO:0005737;endomembrane system#GO:0012505 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0030887|UniProtKB=Q9VWZ7 Q9VWZ7 CT21241 PTHR23192:SF92 OLFACTOMEDIN-RELATED FI21454P1 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 DROME|FlyBase=FBgn0000037|UniProtKB=P16395 P16395 mAChR-A PTHR24247:SF265 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR DM1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;molecular transducer activity#GO:0060089;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;acetylcholine receptor activity#GO:0015464 cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 DROME|FlyBase=FBgn0004875|UniProtKB=Q8MSX1 Q8MSX1 enc PTHR15672:SF8 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN PROTEIN ENCORE DROME|FlyBase=FBgn0031132|UniProtKB=Q9VRC1 Q9VRC1 GPAT PTHR23063:SF2 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4, ISOFORM D-RELATED cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0024956|UniProtKB=Q7KPG8 Q7KPG8 Mat1 PTHR12683:SF13 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991 chaperone#PC00072 DROME|FlyBase=FBgn0038282|UniProtKB=Q9VFD9 Q9VFD9 dpr9 PTHR23279:SF47 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 9, ISOFORM A cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589 DROME|FlyBase=FBgn0261703|UniProtKB=Q9VXW7 Q9VXW7 gce PTHR23042:SF107 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS FI10506P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0023515|UniProtKB=Q7KW09 Q7KW09 Gcna PTHR23099:SF0 TRANSCRIPTIONAL REGULATOR GERM CELL NUCLEAR ACIDIC PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024 DROME|FlyBase=FBgn0036732|UniProtKB=Q9VVH9 Q9VVH9 Oatp74D PTHR11388:SF76 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 74D active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0035192|UniProtKB=Q9W0J0 Q9W0J0 galene PTHR11003:SF358 POTASSIUM CHANNEL, SUBFAMILY K BCDNA.GH04802-RELATED transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0038924|UniProtKB=Q95SI7 Q95SI7 Dmel\CG6028 PTHR42796:SF4 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED OXALOACETATE TAUTOMERASE FAHD2A, MITOCHONDRIAL hydrolase#PC00121 DROME|FlyBase=FBgn0053853|UniProtKB=Q4AB57 Q4AB57 His2A:CG33859 PTHR23430:SF390 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0283480|UniProtKB=Q9W274 Q9W274 Alp2 PTHR11596:SF91 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0031114|UniProtKB=Q9VR99 Q9VR99 cactin PTHR21737:SF4 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 SPLICING FACTOR CACTIN RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039994|UniProtKB=Q8T0G4 Q8T0G4 conu PTHR14963:SF1 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN CONUNDRUM molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of cell communication#GO:0010646;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832;regulation of intracellular signal transduction#GO:1902531;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0004915|UniProtKB=P29052 P29052 TfIIB PTHR11618:SF85 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION INITIATION FACTOR IIB protein binding#GO:0005515;binding#GO:0005488;transcription factor binding#GO:0008134 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259 General transcription regulation#P00023>TFIIB#P00668;Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397 DROME|FlyBase=FBgn0013278|UniProtKB=Q9BIS2 Q9BIS2 Hsp70Bb PTHR19375:SF518 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN AA-RELATED protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817 biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 Hsp70 family chaperone#PC00027;chaperone#PC00072 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 DROME|FlyBase=FBgn0034237|UniProtKB=Q0E940 Q0E940 eIF3b PTHR14068:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 DROME|FlyBase=FBgn0010053|UniProtKB=Q7JRC3 Q7JRC3 Jheh1 PTHR21661:SF35 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803 metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 DROME|FlyBase=FBgn0052675|UniProtKB=Q9W2S1 Q9W2S1 Tango5 PTHR10281:SF121 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 cellular component organization#GO:0016043;Golgi organization#GO:0007030;catabolic process#GO:0009056;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;macroautophagy#GO:0016236;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0043576|UniProtKB=C0HK98 C0HK98 PGRP-SC1a PTHR11022:SF75 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN SB1-RELATED signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783 defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0028707|UniProtKB=Q9VKB3 Q9VKB3 Mt2 PTHR46098:SF1 TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 DROME|FlyBase=FBgn0004197|UniProtKB=P18168 P18168 Ser PTHR24044:SF448 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Serrate#P01104;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Next#P01103 DROME|FlyBase=FBgn0054033|UniProtKB=Q6IGS3 Q6IGS3 Dmel\CG34033 PTHR45710:SF8 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN CONTAINING 5A-RELATED signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0033998|UniProtKB=A0A0B4KER0 A0A0B4KER0 row PTHR24408:SF60 ZINC FINGER PROTEIN RELATIVE OF WOC, ISOFORM C DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0024315|UniProtKB=Q9V7S5 Q9V7S5 Picot PTHR11662:SF247 SOLUTE CARRIER FAMILY 17 INORGANIC PHOSPHATE COTRANSPORTER-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034858|UniProtKB=Q9W1Q8 Q9W1Q8 eIF2Bdelta PTHR10233:SF14 TRANSLATION INITIATION FACTOR EIF-2B TRANSLATION INITIATION FACTOR EIF2B SUBUNIT DELTA translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152 protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0032051|UniProtKB=Q9VLK1 Q9VLK1 Dmel\CG13097 PTHR17039:SF0 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0289578|UniProtKB=Q960D4 Q960D4 EG:22E5.5 PTHR43557:SF2 APOPTOSIS-INDUCING FACTOR 1 RIESKE DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824 oxidoreductase#PC00176 DROME|FlyBase=FBgn0263706|UniProtKB=M9PHU0 M9PHU0 CG12432 PTHR12877:SF7 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR DH DOMAIN-CONTAINING PROTEIN enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;organelle organization#GO:0006996;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0031052|UniProtKB=Q9VWE6 Q9VWE6 Elys PTHR21583:SF8 ELYS PROTEIN PROTEIN ELYS scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037383|UniProtKB=Q9VNI9 Q9VNI9 Sec20 PTHR12825:SF0 BNIP1-RELATED VESICLE TRANSPORT PROTEIN SEC20 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane protein complex#GO:0098796;membrane#GO:0016020;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0051561|UniProtKB=Q8IPR4 Q8IPR4 Osi16 PTHR21879:SF9 FI03362P-RELATED-RELATED OSIRIS 16 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0011281|UniProtKB=P54193 P54193 Obp83a PTHR11857:SF45 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 83A-RELATED system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0026252|UniProtKB=Q9VSD6 Q9VSD6 msk PTHR10997:SF18 IMPORTIN-7, 8, 11 D-IMPORTIN 7_RANBP7 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;organelle envelope#GO:0031967 transporter#PC00227 DROME|FlyBase=FBgn0034709|UniProtKB=Q7JWQ7 Q7JWQ7 Swim PTHR12411:SF1062 CYSTEINE PROTEASE FAMILY C1-RELATED SI:DKEY-158B13.1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 DROME|FlyBase=FBgn0020391|UniProtKB=Q9V6K3 Q9V6K3 Nrk PTHR24416:SF317 TYROSINE-PROTEIN KINASE RECEPTOR MUSCLE, SKELETAL RECEPTOR TYROSINE-PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036620|UniProtKB=Q9VV47 Q9VV47 Dmel\CG4842 PTHR44229:SF8 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] ALCOHOL DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 DROME|FlyBase=FBgn0029754|UniProtKB=Q9W4D3 Q9W4D3 Dmel\CG15930 PTHR22948:SF29 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051345|UniProtKB=Q9VG26 Q9VG26 CG10135 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0037536|UniProtKB=A0A0B4K6B9 A0A0B4K6B9 Dmel\CG2698 PTHR21716:SF4 TRANSMEMBRANE PROTEIN TRANSMEMBRANE PROTEIN 245 cellular process#GO:0009987;transport#GO:0006810;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0040239|UniProtKB=Q9V3L0 Q9V3L0 bc10 PTHR13259:SF1 BLADDER CANCER 10 KD PROTEIN HOMOLOG APOPTOSIS INDUCING FACTOR BLCAP DROME|FlyBase=FBgn0038136|UniProtKB=Q9VFW9 Q9VFW9 Dmel\CG8774 PTHR11533:SF306 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787 catabolic process#GO:0009056;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;proteolysis#GO:0006508;circulatory system process#GO:0003013;biological regulation#GO:0065007;biosynthetic process#GO:0009058;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;peptide catabolic process#GO:0043171;protein processing#GO:0016485;peptide hormone processing#GO:0016486;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0286809|UniProtKB=Q9U3V9 Q9U3V9 xmas PTHR12436:SF39 80 KDA MCM3-ASSOCIATED PROTEIN GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179 nucleus#GO:0005634;organelle#GO:0043226;transcription export complex 2#GO:0070390;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051832|UniProtKB=Q7KT80 Q7KT80 DS00929.7 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0002732|UniProtKB=O97178 O97178 E(spl)malpha-BFM PTHR12254:SF0 ENHANCER OF SPLIT MALPHA PROTEIN BARBU-RELATED DROME|FlyBase=FBgn0004888|UniProtKB=Q94522 Q94522 Scsalpha1 PTHR11117:SF2 SUCCINYL-COA LIGASE SUBUNIT ALPHA SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;ligase#PC00142 TCA cycle#P00051>Succinyl CoA Synthetase#P01274 DROME|FlyBase=FBgn0264493|UniProtKB=Q9VFP2 Q9VFP2 rdx PTHR24413:SF240 SPECKLE-TYPE POZ PROTEIN PROTEIN ROADKILL ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0038705|UniProtKB=A0A6H2EEF7 A0A6H2EEF7 Dmel\CG11626 PTHR11010:SF5 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED RE36938P-RELATED serine protease#PC00203 DROME|FlyBase=FBgn0264325|UniProtKB=Q9VCE1 Q9VCE1 Atg6 PTHR12768:SF4 BECLIN 1 BECLIN-1 protein binding#GO:0005515;phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;establishment of localization#GO:0051234;mitophagy#GO:0000423;intracellular transport#GO:0046907;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;transport#GO:0006810;vacuolar transport#GO:0007034;cellular response to nutrient levels#GO:0031669;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;autophagy#GO:0006914 membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;phosphatidylinositol 3-kinase complex, class III#GO:0035032;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 protease inhibitor#PC00191 DROME|FlyBase=FBgn0031804|UniProtKB=Q9VME7 Q9VME7 AAF52372 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0035849|UniProtKB=Q8WS79 Q8WS79 ERR PTHR48092:SF22 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN-RELATED RECEPTOR SPLICE VARIANT sequence-specific double-stranded DNA binding#GO:1990837;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0029807|UniProtKB=Q9W475 Q9W475 Dmel\CG3108 PTHR11705:SF161 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI01817P-RELATED peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0022359|UniProtKB=O96299 O96299 Sord2 PTHR43161:SF29 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 carbohydrate catabolic process#GO:0016052;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;hexose biosynthetic process#GO:0019319;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;alcohol metabolic process#GO:0006066;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0040305|UniProtKB=A8JNP3 A8JNP3 MTF-1 PTHR46179:SF25 ZINC FINGER PROTEIN METAL RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR-1, ISOFORM C regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0052668|UniProtKB=Q8IR94 Q8IR94 Dmel\CG32668 PTHR21356:SF1 ARMADILLO REPEAT CONTAINING 2 ARMADILLO REPEAT-CONTAINING PROTEIN 2 cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 DROME|FlyBase=FBgn0011824|UniProtKB=Q7KVQ0 Q7KVQ0 Gar1 PTHR23237:SF6 NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1 nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA-templated DNA biosynthetic process#GO:0006278;rRNA metabolic process#GO:0016072;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;telomere organization#GO:0032200;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;telomere maintenance via telomerase#GO:0007004;telomere maintenance via telomere lengthening#GO:0010833;gene expression#GO:0010467;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA modification#GO:0000154;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0053202|UniProtKB=Q8MRE6 Q8MRE6 dpr11 PTHR23279:SF21 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 11, ISOFORM B-RELATED cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253 DROME|FlyBase=FBgn0027079|UniProtKB=A0A0B4KF06 A0A0B4KF06 ValRS PTHR11946:SF93 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE-RELATED catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0029172|UniProtKB=Q9VTD4 Q9VTD4 Fad2 PTHR11351:SF104 ACYL-COA DESATURASE DESATURASE 1, ISOFORM A-RELATED transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;unsaturated fatty acid biosynthetic process#GO:0006636;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 DROME|FlyBase=FBgn0037263|UniProtKB=Q9VN41 Q9VN41 slx1 PTHR20208:SF10 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 DROME|FlyBase=FBgn0000524|UniProtKB=Q23985 Q23985 dx PTHR12622:SF4 DELTEX-RELATED PROTEIN DELTEX acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032517|UniProtKB=Q9VJY7 Q9VJY7 FBgn 32517 PTHR15180:SF1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;rRNA transcription#GO:0009303;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription factor TFIIIC complex#GO:0000127;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0050414|UniProtKB=C5WLM7 C5WLM7 CG30414-RA PTHR24256:SF546 TRYPTASE-RELATED MIP11562P-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0053239|UniProtKB=Q7KV15 Q7KV15 Ste:CG33239 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0037069|UniProtKB=Q9VP53 Q9VP53 Cpr78Cc PTHR10380:SF238 CUTICLE PROTEIN CUTICULAR PROTEIN 65EA-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0036891|UniProtKB=Q9VW19 Q9VW19 Dmel\CG9372 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035405|UniProtKB=Q9VZU3 Q9VZU3 pfk PTHR23110:SF113 BTB DOMAIN TRANSCRIPTION FACTOR FI07618P-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0033153|UniProtKB=A1Z6W5 A1Z6W5 Gadd45 PTHR10411:SF8 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 FI09246P protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0011769|UniProtKB=P37193 P37193 Fdx1 PTHR23426:SF78 FERREDOXIN/ADRENODOXIN FERREDOXIN-2, MITOCHONDRIAL metabolic process#GO:0008152;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 DROME|FlyBase=FBgn0027453|UniProtKB=Q9VKN8 Q9VKN8 Dnz1 PTHR22883:SF405 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0004839|UniProtKB=Q6AWJ9 Q6AWJ9 otk PTHR10075:SF102 BASIGIN RELATED OFF-TRACK2-RELATED regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0031596|UniProtKB=Q9VQY5 Q9VQY5 Dmel\CG15429 PTHR21281:SF0 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0270928|UniProtKB=O17444 O17444 VAChT PTHR23506:SF13 GH10249P VESICULAR ACETYLCHOLINE TRANSPORTER active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular process#GO:0009987;regulation of biological process#GO:0050789 cell junction#GO:0030054;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin vesicle coat#GO:0030125;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;presynapse#GO:0098793;neuron projection#GO:0043005;coated membrane#GO:0048475;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;synapse#GO:0045202;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;cell projection#GO:0042995;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;organelle membrane#GO:0031090;axon terminus#GO:0043679;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane#GO:0005886;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;trans-Golgi network transport vesicle#GO:0030140;axon#GO:0030424;AP-1 adaptor complex#GO:0030121;neuron projection terminus#GO:0044306;distal axon#GO:0150034;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797 secondary carrier transporter#PC00258;transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>VAChT#P01065;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078 DROME|FlyBase=FBgn0031660|UniProtKB=Q9VMX0 Q9VMX0 mRpL28 PTHR13528:SF3 39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0259685|UniProtKB=P10040 P10040 crb PTHR24044:SF515 NOTCH LIGAND FAMILY MEMBER PROTEIN CRUMBS protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0051638|UniProtKB=Q9VMC7 Q9VMC7 CG9545 PTHR46292:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102A DROME|FlyBase=FBgn0037270|UniProtKB=Q9VN50 Q9VN50 eIF3f1 PTHR10540:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F binding#GO:0005488;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;protein binding#GO:0005515;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;translation factor activity#GO:0180051;translation initiation factor binding#GO:0031369;catalytic activity, acting on a protein#GO:0140096;translation initiation factor activity#GO:0003743;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0028425|UniProtKB=Q9VKC2 Q9VKC2 JhI-21 PTHR11785:SF539 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER PROTEIN JHI-21 L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171 transport#GO:0006810;cellular process#GO:0009987;amino acid transport#GO:0006865;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0000928|UniProtKB=Q9W4W2 Q9W4W2 fs(1)Yb PTHR22655:SF2 ATP-DEPENDENT RNA HELICASE TDRD12-RELATED ATP-DEPENDENT RNA HELICASE TDRD12-RELATED regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;piRNA processing#GO:0034587;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0030349|UniProtKB=Q76NS2 Q76NS2 Dmel\CG10353 PTHR12308:SF83 ANOCTAMIN ANOCTAMIN intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;lipid transport#GO:0006869 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0283681|UniProtKB=Q9VV41 Q9VV41 Tcs3 PTHR11735:SF14 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0034876|UniProtKB=Q9W1N4 Q9W1N4 wmd PTHR19877:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;cellular anatomical structure#GO:0110165;SMN complex#GO:0032797;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719 translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0042126|UniProtKB=Q9I7N1 Q9I7N1 Dmel\CG18788 PTHR11662:SF415 SOLUTE CARRIER FAMILY 17 AT30085P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0013323|UniProtKB=X2JCX9 X2JCX9 Ptth PTHR39940:SF5 PROTHORACICOTROPIC HORMONE, ISOFORM F PROTHORACICOTROPIC HORMONE, ISOFORM F neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;positive regulation of metabolic process#GO:0009893;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of lipid metabolic process#GO:0019216;biological regulation#GO:0065007;regulation of steroid biosynthetic process#GO:0050810;regulation of lipid biosynthetic process#GO:0046890;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 DROME|FlyBase=FBgn0050354|UniProtKB=Q4QPY6 Q4QPY6 UQCR-11L PTHR15336:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;reductase#PC00198 DROME|FlyBase=FBgn0259728|UniProtKB=A1Z7R9 A1Z7R9 Dmel\CG42382 PTHR21099:SF2 RAD201 C3H1-TYPE DOMAIN-CONTAINING PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0002354|UniProtKB=Q9VG00 Q9VG00 l(3)87Df PTHR31586:SF1 CYTOCHROME C OXIDASE PROTEIN 20 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0039667|UniProtKB=Q9VAK7 Q9VAK7 FipoQ PTHR20933:SF4 F-BOX ONLY PROTEIN 33 F-BOX INVOLVED IN POLYQ PATHOGENESIS, ISOFORM A DROME|FlyBase=FBgn0025815|UniProtKB=Q9V461 Q9V461 Mcm6 PTHR11630:SF43 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound metabolic process#GO:0006139;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;DNA repair#GO:0006281;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;MCM complex#GO:0042555;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0033210|UniProtKB=Q9V4Q8 Q9V4Q8 U2A PTHR10552:SF11 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0002565|UniProtKB=Q24388 Q24388 Lsp2 PTHR11511:SF5 LARVAL STORAGE PROTEIN/PHENOLOXIDASE FAT-BODY PROTEIN 1-RELATED DROME|FlyBase=FBgn0052638|UniProtKB=Q8IR72 Q8IR72 Dmel\CG32638 PTHR16521:SF4 TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN FI19011P1 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030366|UniProtKB=Q9VYQ8 Q9VYQ8 Usp7 PTHR24006:SF644 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0035012|UniProtKB=Q9W165 Q9W165 Dmel\CG13590 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0000442|UniProtKB=Q03042 Q03042 Pkg21D PTHR24353:SF161 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED receptor guanylyl cyclase signaling pathway#GO:0007168;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 DROME|FlyBase=FBgn0024236|UniProtKB=Q9VSL7 Q9VSL7 foi PTHR12191:SF30 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER FOI monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0035271|UniProtKB=Q9W087 Q9W087 l(3)neo7 PTHR15588:SF9 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 U6 snRNP#GO:0005688;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0035791|UniProtKB=Q9VS80 Q9VS80 Dmel\CG8539 PTHR11705:SF140 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI02848P-RELATED hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0024975|UniProtKB=Q960Q9 Q960Q9 EG:95B7.7 PTHR24381:SF393 ZINC FINGER PROTEIN LD39664P-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0035515|UniProtKB=Q9VZF6 Q9VZF6 Sqor PTHR10632:SF2 SULFIDE:QUINONE OXIDOREDUCTASE SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 DROME|FlyBase=FBgn0261931|UniProtKB=Q9W326 Q9W326 Hecw PTHR11254:SF320 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE HECT-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;regulation of dendrite morphogenesis#GO:0048814;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of developmental process#GO:0050793;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;biological regulation#GO:0065007;metabolic process#GO:0008152;regulation of cell projection organization#GO:0031344;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031661|UniProtKB=Q9VMW9 Q9VMW9 Gmd PTHR43715:SF1 GDP-MANNOSE 4,6-DEHYDRATASE GDP-MANNOSE 4,6 DEHYDRATASE lyase#PC00144;dehydratase#PC00091 Mannose metabolism#P02752>GDP-Mannose 4,6-dehydratase#P03015 DROME|FlyBase=FBgn0023495|UniProtKB=O46108 O46108 Lip3 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 hydrolase#PC00121;lipase#PC00143 DROME|FlyBase=FBgn0051835|UniProtKB=Q7KT86 Q7KT86 BG:DS00810.1 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0285913|UniProtKB=Q961C8 Q961C8 red PTHR20932:SF8 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 1-RELATED DROME|FlyBase=FBgn0053919|UniProtKB=A1Z6L8 A1Z6L8 Dmel\CG33919 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0026872|UniProtKB=Q9W588 Q9W588 Dmel\CG14777 PTHR11266:SF75 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 IP10007P-RELATED cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0031492|UniProtKB=Q9VQK5 Q9VQK5 Prp40 PTHR11864:SF0 PRE-MRNA-PROCESSING PROTEIN PRP40 PRE-MRNA-PROCESSING FACTOR 40 HOMOLOG A nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525 DROME|FlyBase=FBgn0002044|UniProtKB=Q9VIV2 Q9VIV2 swm PTHR14398:SF0 RNA RECOGNITION RRM/RNP DOMAIN ZINC FINGER PROTEIN SWM RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0261565|UniProtKB=Q7KUQ6 Q7KUQ6 Lmpt PTHR13270:SF15 PROTEIN C20ORF116-RELATED LIMPET, ISOFORM K DROME|FlyBase=FBgn0035838|UniProtKB=Q9VSD7 Q9VSD7 ldbr PTHR12849:SF0 RNA LARIAT DEBRANCHING ENZYME LARIAT DEBRANCHING ENZYME RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound catabolic process#GO:0034655;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 endoribonuclease#PC00094 DROME|FlyBase=FBgn0039023|UniProtKB=Q9VCU2 Q9VCU2 Nepl14 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0034475|UniProtKB=Q9V8Y9 Q9V8Y9 Obp56h PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0034096|UniProtKB=A1ZAC2 A1ZAC2 Dmel\CG7786 PTHR11988:SF55 THYROTROPH EMBRYONIC FACTOR RELATED BZIP DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0053481|UniProtKB=A8DZ27 A8DZ27 dpr7 PTHR23279:SF6 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 7, ISOFORM F cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 DROME|FlyBase=FBgn0267792|UniProtKB=E1JH10 E1JH10 rgr PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0050183|UniProtKB=Q9W1L2 Q9W1L2 CG4093 PTHR21538:SF23 ANILLIN/RHOTEKIN RTKN ANILLIN cellular process#GO:0009987;actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;septin cytoskeleton organization#GO:0032185;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cell division#GO:0051301;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;cortical actin cytoskeleton organization#GO:0030866;septin ring organization#GO:0031106;cytoskeleton-dependent cytokinesis#GO:0061640 cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoskeleton#GO:0005856;contractile ring#GO:0070938;actomyosin contractile ring#GO:0005826;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0037551|UniProtKB=Q9VHV5 Q9VHV5 Arl8 PTHR45732:SF23 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 lysosomal transport#GO:0007041;axonal transport#GO:0098930;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;anterograde axonal transport#GO:0008089;microtubule-based movement#GO:0007018;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;endosomal transport#GO:0016197;microtubule-based process#GO:0007017;axo-dendritic transport#GO:0008088;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737 Huntington disease#P00029>ARF#P00786 DROME|FlyBase=FBgn0039358|UniProtKB=Q8MT18 Q8MT18 Idh3g PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;alcohol metabolic process#GO:0006066;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0039739|UniProtKB=Q9VAB9 Q9VAB9 RpS28a PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN ES28 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 DROME|FlyBase=FBgn0283536|UniProtKB=Q9XZH6 Q9XZH6 Vha13 PTHR12713:SF39 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G cellular component organization#GO:0016043;homeostatic process#GO:0042592;transmembrane transport#GO:0055085;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;developmental maturation#GO:0021700;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;proton transmembrane transport#GO:1902600;synaptic vesicle maturation#GO:0016188;vesicle organization#GO:0016050;cellular homeostasis#GO:0019725 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469;cellular anatomical structure#GO:0110165;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ATP synthase#PC00002 DROME|FlyBase=FBgn0033033|UniProtKB=Q7K5M0 Q7K5M0 scaf PTHR24260:SF147 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED DROME|FlyBase=FBgn0031548|UniProtKB=Q9VQS3 Q9VQS3 Dmel\CG8852 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0024909|UniProtKB=Q9VHY5 Q9VHY5 Taf7 PTHR12228:SF0 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 DROME|FlyBase=FBgn0053489|UniProtKB=Q7KUG5 Q7KUG5 CG6110 PTHR12086:SF12 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;reproductive process#GO:0022414;regulation of calcium-mediated signaling#GO:0050848;cell motility#GO:0048870;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;regulation of metal ion transport#GO:0010959;sperm motility#GO:0097722;regulation of biological process#GO:0050789;cilium-dependent cell motility#GO:0060285;regulation of signaling#GO:0023051;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;regulation of calcineurin-NFAT signaling cascade#GO:0070884;microtubule-based process#GO:0007017;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of response to stimulus#GO:0048583;flagellated sperm motility#GO:0030317 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic microtubule#GO:0005881;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0032381|UniProtKB=Q9VKE6 Q9VKE6 Mal-B1 PTHR10357:SF235 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A3-RELATED metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313 metabolite interconversion enzyme#PC00262;amylase#PC00048 DROME|FlyBase=FBgn0030136|UniProtKB=Q9W334 Q9W334 RpS28b PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN ES28 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;organelle assembly#GO:0070925;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;rRNA metabolic process#GO:0016072 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 DROME|FlyBase=FBgn0034624|UniProtKB=Q9W2H3 Q9W2H3 Dmel\CG17974 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0264089|UniProtKB=P24014 P24014 sli PTHR45836:SF4 SLIT HOMOLOG PROTEIN SLIT cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 DROME|FlyBase=FBgn0035267|UniProtKB=A0A4D6K3Y7 A0A4D6K3Y7 Dmel\CG13921 PTHR39952:SF1 FI02073P SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0031981|UniProtKB=Q9VLT6 Q9VLT6 Megf8 PTHR23244:SF485 KELCH REPEAT DOMAIN MULTIPLE EGF LIKE DOMAINS 8, ISOFORM B cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 DROME|FlyBase=FBgn0024361|UniProtKB=O46101 O46101 Tsp2A PTHR19282:SF555 TETRASPANIN TETRASPANIN-2A cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0026176|UniProtKB=Q7KJ69 Q7KJ69 SkpB PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0039690|UniProtKB=Q9VAI0 Q9VAI0 Gnpnat PTHR13355:SF11 GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;glucosamine 6-phosphate N-acetyltransferase activity#GO:0004343;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038 DROME|FlyBase=FBgn0002901|UniProtKB=Q9VVN4 Q9VVN4 mus304 PTHR28594:SF1 ATR-INTERACTING PROTEIN ATR-INTERACTING PROTEIN DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 DROME|FlyBase=FBgn0037024|UniProtKB=Q8IPU3 Q8IPU3 tzn PTHR11935:SF94 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 DROME|FlyBase=FBgn0032514|UniProtKB=Q9VJZ1 Q9VJZ1 anon-WO0118547.80 PTHR45672:SF2 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE A5 catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 chaperone#PC00072 DROME|FlyBase=FBgn0039565|UniProtKB=Q9VAX9 Q9VAX9 Dmel\CG4884 PTHR13633:SF3 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0085326|UniProtKB=A8JQU5 A8JQU5 Dmel\CG34297 PTHR46540:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 12 TETRATRICOPEPTIDE REPEAT PROTEIN 12 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;protein-containing complex assembly#GO:0065003;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0027364|UniProtKB=Q9Y1P6 Q9Y1P6 Six4 PTHR10390:SF44 HOMEOBOX PROTEIN SIX SIX HOMEOBOX 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0250839|UniProtKB=A0A0B4KF22 A0A0B4KF22 Jhbp2 PTHR11008:SF31 PROTEIN TAKEOUT-LIKE PROTEIN JUVENILE HORMONE BINDING PROTEIN 2, ISOFORM E rhythmic process#GO:0048511;circadian rhythm#GO:0007623 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028969|UniProtKB=Q9W555 Q9W555 deltaCOP PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;organelle localization#GO:0051640;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;vesicle-mediated transport#GO:0016192 vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0266711|UniProtKB=Q7JWD6 Q7JWD6 EloC PTHR20648:SF0 ELONGIN-C ELONGIN-C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 DROME|FlyBase=FBgn0017561|UniProtKB=Q94526 Q94526 Ork1 PTHR11003:SF331 POTASSIUM CHANNEL, SUBFAMILY K OPEN RECTIFIER POTASSIUM CHANNEL PROTEIN 1 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transport#GO:0006813;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0034768|UniProtKB=Q9W209 Q9W209 Obp58b PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0038038|UniProtKB=Q9VG81 Q9VG81 Sccpdh2 PTHR12286:SF5 SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247 cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0036499|UniProtKB=Q7KUM9 Q7KUM9 Dmel\CG7276 PTHR21255:SF7 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0038788|UniProtKB=Q9I7I7 Q9I7I7 Sirt2 PTHR11085:SF6 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2 deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213 nucleolus organization#GO:0007000;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0037644|UniProtKB=Q9VHJ7 Q9VHJ7 Dmel\CG11964 PTHR14978:SF0 BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN BETA-CATENIN-LIKE PROTEIN 1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0052708|UniProtKB=Q9W394 Q9W394 Dmel\CG32708 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 DROME|FlyBase=FBgn0086712|UniProtKB=Q5U117 Q5U117 Egm PTHR48083:SF2 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED COMPLEX I ASSEMBLY FACTOR EGM, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 DROME|FlyBase=FBgn0050077|UniProtKB=A1Z9S1 A1Z9S1 Blos1 PTHR13073:SF0 BLOC-1 COMPLEX SUBUNIT 1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 protein-containing complex#GO:0032991;BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0025185|UniProtKB=Q5BIC3 Q5BIC3 az2 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0015033|UniProtKB=Q9VS79 Q9VS79 Cyp4d8 PTHR24291:SF187 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4AE1-RELATED oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0037985|UniProtKB=Q9VGD8 Q9VGD8 ssp5 PTHR41967:SF6 FI19406P1-RELATED FI19406P1-RELATED DROME|FlyBase=FBgn0027504|UniProtKB=Q7KMI3 Q7KMI3 bsd PTHR11909:SF422 CASEIN KINASE-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0038772|UniProtKB=Q9VDP8 Q9VDP8 mdlc PTHR12930:SF0 ZINC FINGER PROTEIN 183 RING FINGER PROTEIN 113A1 catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0029912|UniProtKB=Q9W3V2 Q9W3V2 Tmf PTHR46515:SF1 TATA ELEMENT MODULATORY FACTOR TMF1 TATA ELEMENT MODULATORY FACTOR intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 DROME|FlyBase=FBgn0086778|UniProtKB=E1JJR2 E1JJR2 nAChRalpha7 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;trans-synaptic signaling#GO:0099537 signaling receptor complex#GO:0043235;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 DROME|FlyBase=FBgn0028427|UniProtKB=Q9V400 Q9V400 Ilk PTHR44329:SF57 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED SCAFFOLD PROTEIN ILK kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular adaptor activity#GO:0060090;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein-macromolecule adaptor activity#GO:0030674;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773 developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>ILK#P00935 DROME|FlyBase=FBgn0015818|UniProtKB=Q9W424 Q9W424 Spx PTHR48030:SF7 SPLICING FACTOR 3B SUBUNIT 4 SPLICING FACTOR 3B SUBUNIT 4 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0031533|UniProtKB=Q9VQQ5 Q9VQQ5 Dmel\CG2772 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0036566|UniProtKB=Q9VUY1 Q9VUY1 ClC-c PTHR45711:SF12 CHLORIDE CHANNEL PROTEIN CHLORIDE CHANNEL PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078 renal system process#GO:0003014;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;multicellular organismal process#GO:0032501;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;system process#GO:0003008;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0035982|UniProtKB=Q9VSX2 Q9VSX2 BEST:GH12586 PTHR45640:SF40 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN 22-RELATED macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;response to heat#GO:0009408;protein refolding#GO:0042026;protein metabolic process#GO:0019538;protein folding#GO:0006457;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 DROME|FlyBase=FBgn0038983|UniProtKB=Q9VCZ0 Q9VCZ0 Dmel\CG5326 PTHR11157:SF28 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0034420|UniProtKB=B7YZL3 B7YZL3 10737 PTHR21119:SF5 C2 DOMAIN-CONTAINING PROTEIN C2 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0039595|UniProtKB=Q9NBC8 Q9NBC8 AstA-R2 PTHR24230:SF75 G-PROTEIN COUPLED RECEPTOR ALLATOSTATIN A RECEPTOR 2, ISOFORM A molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0010424|UniProtKB=P47949 P47949 TpnC73F PTHR23050:SF244 CALCIUM BINDING PROTEIN TROPONIN C, ISOFORM 2-RELATED ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0032593|UniProtKB=Q9VJJ7 Q9VJJ7 Trpgamma PTHR10117:SF54 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN binding#GO:0005488;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 DROME|FlyBase=FBgn0033287|UniProtKB=Q7K2U6 Q7K2U6 anon-WO0140519.78 PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0032642|UniProtKB=Q9VJD2 Q9VJD2 Lamtor3 PTHR13378:SF1 REGULATOR COMPLEX PROTEIN LAMTOR3 RAGULATOR COMPLEX PROTEIN LAMTOR3 positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of TORC1 signaling#GO:1904263;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0004783|UniProtKB=Q9V3L8 Q9V3L8 Ccp84Aa PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038201|UniProtKB=Q8ITC9 Q8ITC9 PK1-R PTHR24243:SF237 G-PROTEIN COUPLED RECEPTOR PYROKININ-1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0029095|UniProtKB=Q8IPW1 Q8IPW1 aru PTHR12287:SF23 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN AROUSER, ISOFORM A-RELATED cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0000036|UniProtKB=P09478 P09478 nAChRalpha1 PTHR18945:SF945 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-LIKE 1 gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261 anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;synaptic transmission, cholinergic#GO:0007271;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;signaling receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 DROME|FlyBase=FBgn0039298|UniProtKB=Q9VBV3 Q9VBV3 to PTHR11008:SF32 PROTEIN TAKEOUT-LIKE PROTEIN GH08336P-RELATED rhythmic process#GO:0048511;circadian rhythm#GO:0007623 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0032818|UniProtKB=Q9I7M2 Q9I7M2 CG10628 PTHR11702:SF43 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED GTP-BINDING PROTEIN 10 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0085271|UniProtKB=A1A6X2 A1A6X2 CG34242-RA PTHR34923:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 20 SMALL INTEGRAL MEMBRANE PROTEIN 20 protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0052382|UniProtKB=Q9VS71 Q9VS71 sphinx2 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0085421|UniProtKB=A1Z6P8 A1Z6P8 Epac PTHR23113:SF327 GUANINE NUCLEOTIDE EXCHANGE FACTOR EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CAMP, ISOFORM E molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0030010|UniProtKB=Q9W3J2 Q9W3J2 Dmel\CG10959 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0035088|UniProtKB=Q9W0X3 Q9W0X3 DmP29 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0030122|UniProtKB=Q9W351 Q9W351 Aladin PTHR14494:SF0 ALADIN/ADRACALIN/AAAS ALADIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0011828|UniProtKB=Q9VZZ4 Q9VZZ4 Pxn PTHR11475:SF147 OXIDASE/PEROXIDASE PEROXIDASIN peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 DROME|FlyBase=FBgn0033272|UniProtKB=Q7K519 Q7K519 RagC-D PTHR11259:SF2 RAS-RELATED GTP BINDING RAG/GTR YEAST GH16429P guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 negative regulation of catabolic process#GO:0009895;positive regulation of TOR signaling#GO:0032008;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;response to nutrient levels#GO:0031667;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987 nucleus#GO:0005634;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 DROME|FlyBase=FBgn0037647|UniProtKB=Q9VHJ4 Q9VHJ4 RagA-B PTHR11259:SF1 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 negative regulation of catabolic process#GO:0009895;positive regulation of TOR signaling#GO:0032008;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of TORC1 signaling#GO:1903432;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;response to nutrient levels#GO:0031667;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;nucleus#GO:0005634;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 small GTPase#PC00208 DROME|FlyBase=FBgn0023507|UniProtKB=Q7K511 Q7K511 D2hgdh PTHR43716:SF6 D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0015925|UniProtKB=Q9U6Y9 Q9U6Y9 csul PTHR10738:SF0 PROTEIN ARGININE N-METHYLTRANSFERASE 5 PROTEIN ARGININE N-METHYLTRANSFERASE 5 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003162|UniProtKB=P48596 P48596 Pu PTHR11109:SF7 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 DROME|FlyBase=FBgn0025697|UniProtKB=Q9VM10 Q9VM10 santa-maria PTHR11923:SF93 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 GH07959P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0263977|UniProtKB=Q7PLT4 Q7PLT4 Tim17b PTHR10485:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 AT05822P-RELATED transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 transporter#PC00227 DROME|FlyBase=FBgn0020376|UniProtKB=Q9N2Q3 Q9N2Q3 Sr-CIII PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED DROME|FlyBase=FBgn0042101|UniProtKB=Q9I7K7 Q9I7K7 Dmel\CG18744 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0024889|UniProtKB=O76521 O76521 Kap-alpha1 PTHR23316:SF87 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0037620|UniProtKB=Q9VHM4 Q9VHM4 ranshi PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0035380|UniProtKB=Q9VZX0 Q9VZX0 Dmel\CG9970 PTHR22667:SF0 AT01380P-RELATED AT01380P-RELATED DROME|FlyBase=FBgn0027057|UniProtKB=Q9VVU5 Q9VVU5 CSN1b PTHR14145:SF2 26S PROTESOME SUBUNIT 6 COP9 SIGNALOSOME COMPLEX SUBUNIT 1 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of protein stability#GO:0031647;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;biological regulation#GO:0065007;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0051391|UniProtKB=Q8MSL1 Q8MSL1 CG6471 PTHR21055:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 phosphatase modulator#PC00184 DROME|FlyBase=FBgn0031449|UniProtKB=M9PBX3 M9PBX3 Dmel\CG31689 PTHR48041:SF32 ABC TRANSPORTER G FAMILY MEMBER 28 PROTEIN WHITE-LIKE PROTEIN ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0284246|UniProtKB=Q7K4B2 Q7K4B2 l(2)k09848 PTHR16038:SF4 NOP SEVEN ASSOCIATED PROTEIN 1 WD REPEAT-CONTAINING PROTEIN 74 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA processing factor#PC00147 DROME|FlyBase=FBgn0035642|UniProtKB=Q9VRQ5 Q9VRQ5 Dmel\CG18586 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521 ligase#PC00142 DROME|FlyBase=FBgn0001230|UniProtKB=O97125 O97125 Hsp68 PTHR19375:SF518 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN AA-RELATED protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817 protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 Hsp70 family chaperone#PC00027;chaperone#PC00072 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 DROME|FlyBase=FBgn0261268|UniProtKB=Q8IP45 Q8IP45 Cul3 PTHR11932:SF180 CULLIN CULLIN-3 binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0039808|UniProtKB=Q9VA29 Q9VA29 Dmel\CG12071 PTHR24393:SF114 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0038829|UniProtKB=Q9VDI5 Q9VDI5 Dmel\CG17271 PTHR23104:SF17 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 DROME|FlyBase=FBgn0035601|UniProtKB=Q9VRL1 Q9VRL1 Uev1A PTHR24068:SF143 UBIQUITIN-CONJUGATING ENZYME E2 GEO06356P1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Uev1A#P01376 DROME|FlyBase=FBgn0027779|UniProtKB=Q9V3J1 Q9V3J1 VhaSFD PTHR10698:SF0 V-TYPE PROTON ATPASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT H biological regulation#GO:0065007;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;vacuolar acidification#GO:0007035;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0035099|UniProtKB=Q9W0V0 Q9W0V0 Dmel\CG6845 PTHR21041:SF9 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN-LIKE DOMAIN-CONTAINING PROTEIN reproductive process#GO:0022414;fertilization#GO:0009566;single fertilization#GO:0007338;sexual reproduction#GO:0019953 DROME|FlyBase=FBgn0035713|UniProtKB=Q9VRY4 Q9VRY4 velo PTHR46896:SF3 SENTRIN-SPECIFIC PROTEASE FI06413P-RELATED protease#PC00190;cysteine protease#PC00081 DROME|FlyBase=FBgn0050338|UniProtKB=Q4QQ93 Q4QQ93 Dmel\CG30338 PTHR15955:SF8 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2B ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0051634|UniProtKB=Q8SY02 Q8SY02 Oatp26F PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter#PC00227 DROME|FlyBase=FBgn0053801|UniProtKB=Q4ABE3 Q4ABE3 His1:CG33801 PTHR11467:SF36 HISTONE H1 H1.010 LINKER HISTONE, CLUSTER MEMBER-RELATED chromatin DNA binding#GO:0031490;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682 cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0031397|UniProtKB=Q9VQ86 Q9VQ86 Dmel\CG15385 PTHR11567:SF213 ACID PHOSPHATASE-RELATED 2-PHOSPHOXYLOSE PHOSPHATASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 DROME|FlyBase=FBgn0052057|UniProtKB=Q9VT83 Q9VT83 dpr10 PTHR23279:SF49 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 10, ISOFORM A-RELATED cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253 DROME|FlyBase=FBgn0005696|UniProtKB=Q9VB62 Q9VB62 PolA2 PTHR23061:SF12 DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT DNA POLYMERASE ALPHA SUBUNIT B nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;replication fork#GO:0005657;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0033876|UniProtKB=Q7JYV2 Q7JYV2 Syngr PTHR10838:SF34 SYNAPTOGYRIN SYNAPTOGYRIN cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0034665|UniProtKB=Q9W2C3 Q9W2C3 CG4372 PTHR10188:SF50 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0265003|UniProtKB=A0A0B4KEE4 A0A0B4KEE4 koi PTHR12911:SF48 SAD1/UNC-84-LIKE PROTEIN-RELATED KLAROID PROTEIN-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;membrane#GO:0016020;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0005624|UniProtKB=P35820 P35820 Psc PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0038738|UniProtKB=Q9VDT5 Q9VDT5 anon-WO02059370.13 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 serine protease#PC00203 DROME|FlyBase=FBgn0032266|UniProtKB=Q9VKT7 Q9VKT7 Dmel\CG18302 PTHR11005:SF144 LYSOSOMAL ACID LIPASE-RELATED AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 hydrolase#PC00121;lipase#PC00143 DROME|FlyBase=FBgn0022343|UniProtKB=Q8MMC4 Q8MMC4 CG3760 PTHR16284:SF13 PROTEIN CDV3 HOMOLOG PROTEIN CDV3 HOMOLOG cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0010403|UniProtKB=Q23970 Q23970 Obp83b PTHR11857:SF45 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 83A-RELATED sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0030882|UniProtKB=Q86B44 Q86B44 Gss2 PTHR11130:SF0 GLUTATHIONE SYNTHETASE GLUTATHIONE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ligase#PC00142 DROME|FlyBase=FBgn0015803|UniProtKB=A8DZ19 A8DZ19 RtGEF PTHR46026:SF1 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0004368|UniProtKB=Q9W4F5 Q9W4F5 Ptp4E PTHR19134:SF553 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Axon guidance mediated by Slit/Robo#P00008>Ptp10D#P00343 DROME|FlyBase=FBgn0030817|UniProtKB=M9PHT8 M9PHT8 CT15971 PTHR22950:SF150 AMINO ACID TRANSPORTER FI17861P1 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774 secondary carrier transporter#PC00258;amino acid transporter#PC00046 DROME|FlyBase=FBgn0263121|UniProtKB=Q9XZJ4 Q9XZJ4 Prosalpha1 PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0004047|UniProtKB=P06607 P06607 Yp3 PTHR11610:SF149 LIPASE FI01450P-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0035600|UniProtKB=Q9VRL0 Q9VRL0 Cyt-c1 PTHR10266:SF3 CYTOCHROME C1 CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Huntington disease#P00029>Cytochrome c#P00785;FAS signaling pathway#P00020>CytochromeC#P00620;ATP synthesis#P02721>Cyt bc1#P02799 DROME|FlyBase=FBgn0052676|UniProtKB=Q8SXD4 Q8SXD4 stx PTHR23010:SF1 MIDNOLIN MIDNOLIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0031535|UniProtKB=Q9VQQ7 Q9VQQ7 Dmel\CG12795 PTHR14677:SF46 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein targeting#GO:0006605;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;localization#GO:0051179;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0263197|UniProtKB=A1ZAU8 A1ZAU8 Patronin PTHR21595:SF0 PATRONIN PATRONIN protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 supramolecular fiber organization#GO:0097435;negative regulation of cytoskeleton organization#GO:0051494;microtubule cytoskeleton organization#GO:0000226;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of microtubule-based process#GO:0032886;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;cytoplasmic microtubule organization#GO:0031122;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of protein depolymerization#GO:1901880;regulation of microtubule cytoskeleton organization#GO:0070507;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752 DROME|FlyBase=FBgn0085436|UniProtKB=A0A0B4LEZ3 A0A0B4LEZ3 Not1 PTHR13162:SF8 CCR4-NOT TRANSCRIPTION COMPLEX CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;CCR4-NOT complex#GO:0030014;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0031473|UniProtKB=Q9VQI1 Q9VQI1 Dmel\CG3104 PTHR24120:SF4 GH07239P GH07239P DROME|FlyBase=FBgn0038316|UniProtKB=Q9VF93 Q9VF93 Dmel\CG6276 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0026565|UniProtKB=O97069 O97069 Ass PTHR11587:SF11 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;ligase#PC00142 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 DROME|FlyBase=FBgn0039551|UniProtKB=Q9VAZ3 Q9VAZ3 Or98a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0029840|UniProtKB=Q9W437 Q9W437 raptor PTHR12848:SF22 REGULATORY-ASSOCIATED PROTEIN OF MTOR REGULATORY-ASSOCIATED PROTEIN OF MTOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cellular process#GO:0050794;regulation of growth#GO:0040008;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of catabolic process#GO:0009894;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;TORC1 signaling#GO:0038202;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;positive regulation of growth#GO:0045927;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;positive regulation of cell growth#GO:0030307;TOR signaling#GO:0031929;regulation of cell growth#GO:0001558;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0032016|UniProtKB=Q9VLP7 Q9VLP7 Mettl14 PTHR13107:SF0 N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT N(6)-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT METTL14 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA modification#GO:0016556;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;metabolic process#GO:0008152 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0039182|UniProtKB=Q9VC94 Q9VC94 Rrp5 PTHR23270:SF10 PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5 PROTEIN RRP5 HOMOLOG binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039294|UniProtKB=A0A0B4LHM7 A0A0B4LHM7 Cad96Cb PTHR24028:SF364 CADHERIN-87A CADHERIN 96CB, ISOFORM D cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0029858|UniProtKB=Q9W413 Q9W413 mldr PTHR13547:SF23 RIBONUCLEASE P MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT ribonuclease P activity#GO:0004526;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030066|UniProtKB=Q9W3B3 Q9W3B3 Uros1 PTHR12390:SF0 UROPORPHYRINOGEN III SYNTHASE UROPORPHYRINOGEN-III SYNTHASE hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;small molecule metabolic process#GO:0044281;porphyrin-containing compound metabolic process#GO:0006778;small molecule biosynthetic process#GO:0044283;tetrapyrrole metabolic process#GO:0033013;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Heme biosynthesis#P02746>Uroporphyrinogen-III synthase#P02974 DROME|FlyBase=FBgn0042630|UniProtKB=M9PCG2 M9PCG2 Sox21b PTHR10270:SF338 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0027554|UniProtKB=Q9Y114 Q9Y114 anon-WO0172774.24 PTHR46424:SF1 UBX DOMAIN-CONTAINING PROTEIN 4 UBX DOMAIN-CONTAINING PROTEIN 4 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0037975|UniProtKB=Q9VGF1 Q9VGF1 Dmel\CG3397 PTHR42686:SF1 GH17980P-RELATED GH17980P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0030679|UniProtKB=Q9VXQ7 Q9VXQ7 Dmel\CG8206 PTHR20922:SF13 DNL-TYPE ZINC FINGER PROTEIN DNL-TYPE ZINC FINGER PROTEIN mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein folding#GO:0006457;mitochondrial transport#GO:0006839;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;chaperone-mediated protein complex assembly#GO:0051131;localization#GO:0051179;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein localization to organelle#GO:0033365;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058;protein import into mitochondrial matrix#GO:0030150 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0259791|UniProtKB=Q9VVR2 Q9VVR2 bora PTHR14728:SF2 PROTEIN AURORA BOREALIS PROTEIN AURORA BOREALIS enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 regulation of microtubule-based process#GO:0032886;regulation of mitotic spindle organization#GO:0060236;regulation of mitotic nuclear division#GO:0007088;regulation of organelle organization#GO:0033043;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of spindle organization#GO:0090224;regulation of nuclear division#GO:0051783;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0034282|UniProtKB=Q9V895 Q9V895 Anp32a PTHR11375:SF0 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0039914|UniProtKB=Q9V4E6 Q9V4E6 mav PTHR11848:SF313 TGF-BETA FAMILY MAVERICK receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 DROME|FlyBase=FBgn0289650|UniProtKB=A0A0B4KFF9 A0A0B4KFF9 jbug PTHR38537:SF13 JITTERBUG, ISOFORM N JITTERBUG, ISOFORM N DROME|FlyBase=FBgn0259221|UniProtKB=B7YZF8 B7YZF8 ATP8A PTHR24092:SF150 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;intramembrane lipid carrier activity#GO:0140303 regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0046706|UniProtKB=P83103 P83103 Haspin PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN protein serine/threonine kinase activity#GO:0004674;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0039369|UniProtKB=Q9VBM5 Q9VBM5 CG17195-PA PTHR22883:SF511 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 protein targeting to membrane#GO:0006612;developmental process#GO:0032502;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;developmental maturation#GO:0021700;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;protein targeting#GO:0006605 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039258|UniProtKB=Q9VBZ9 Q9VBZ9 beta4GalT7 PTHR19300:SF30 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 7 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 Wnt signaling pathway#P00057>Calcineurin#P01446 DROME|FlyBase=FBgn0033770|UniProtKB=A1Z949 A1Z949 wuc PTHR31489:SF2 LIN52 FAMILY MEMBER PROTEIN LIN-52 HOMOLOG DROME|FlyBase=FBgn0035265|UniProtKB=Q9W096 Q9W096 PIG-Wb PTHR20661:SF0 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN GLUCOSAMINYL-PHOSPHATIDYLINOSITOL-ACYLTRANSFERASE PIGW acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 DROME|FlyBase=FBgn0035993|UniProtKB=Q9VSY9 Q9VSY9 Nf-YA PTHR12632:SF122 TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 DROME|FlyBase=FBgn0051998|UniProtKB=Q9V4B6 Q9V4B6 CG11578 PTHR35578:SF6 PROLINE-RICH TRANSMEMBRANE PROTEIN 4-RELATED PROLINE-RICH TRANSMEMBRANE PROTEIN 4 DROME|FlyBase=FBgn0014163|UniProtKB=Q95RI5 Q95RI5 fax PTHR12289:SF78 METAXIN RELATED FAILED AXON CONNECTIONS transporter#PC00227 DROME|FlyBase=FBgn0052373|UniProtKB=Q8SYF5 Q8SYF5 Dmel\CG32373 PTHR24034:SF111 EGF-LIKE DOMAIN-CONTAINING PROTEIN RE64043P cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0051975|UniProtKB=Q8IPV2 Q8IPV2 CG18501 PTHR11012:SF55 PROTEIN KINASE-LIKE DOMAIN-CONTAINING T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0032680|UniProtKB=Q9VJ85 Q9VJ85 Ntf-2r PTHR12612:SF48 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643 DROME|FlyBase=FBgn0005642|UniProtKB=P15619 P15619 wdn PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0036454|UniProtKB=Q7KUK9 Q7KUK9 CT39634 PTHR13817:SF155 TITIN IG-LIKE AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN C25G4.10 structural protein#PC00211 DROME|FlyBase=FBgn0030658|UniProtKB=Q9VXT2 Q9VXT2 CG7872 PTHR44176:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0037166|UniProtKB=Q9VNT9 Q9VNT9 WUN-like PTHR10165:SF103 LIPID PHOSPHATE PHOSPHATASE FI04477P-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cell communication#GO:0007154;dephosphorylation#GO:0016311;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0267828|UniProtKB=E1JHE4 E1JHE4 Fatp1 PTHR43107:SF27 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN-FATTY-ACID--COA LIGASE carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid metabolic process#GO:0006629;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;import into cell#GO:0098657;establishment of localization#GO:0051234;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0085446|UniProtKB=M9PDW8 M9PDW8 CG3950 PTHR23167:SF46 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031044|UniProtKB=Q9VWF4 Q9VWF4 MKP-4 PTHR45848:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 DROME|FlyBase=FBgn0267823|UniProtKB=Q9W1X8 Q9W1X8 Gmer PTHR43238:SF1 GDP-L-FUCOSE SYNTHASE GDP-L-FUCOSE SYNTHASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxidoreductase#PC00176 DROME|FlyBase=FBgn0030241|UniProtKB=Q9VZ62 Q9VZ62 feo PTHR19321:SF57 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED FASCETTO-RELATED protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;organelle assembly#GO:0070925;nuclear division#GO:0000280;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0035999|UniProtKB=Q9VSZ5 Q9VSZ5 Dmel\CG3552 PTHR20884:SF8 GDP-D-GLUCOSE PHOSPHORYLASE 1 GDP-D-GLUCOSE PHOSPHORYLASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cellular process#GO:0009987;response to stress#GO:0006950;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0261353|UniProtKB=P0DKM0 P0DKM0 Ccdc56 PTHR15642:SF3 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0038186|UniProtKB=Q9VFQ4 Q9VFQ4 Dmel\CG14362 PTHR46002:SF5 EG:114D9.1 PROTEIN-RELATED EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0036023|UniProtKB=Q9VT24 Q9VT24 Dmel\CG18179 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0003250|UniProtKB=P08255 P08255 Rh4 PTHR24240:SF226 OPSIN OPSIN RH3-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;detection of stimulus#GO:0051606;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;cellular response to radiation#GO:0071478;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0010352|UniProtKB=A8JNU6 A8JNU6 Ogdh1 PTHR23152:SF4 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034901|UniProtKB=Q9W1K1 Q9W1K1 Dmel\CG11300 PTHR48583:SF1 PROLINE-RICH 13 PROLINE-RICH 13 DROME|FlyBase=FBgn0038067|UniProtKB=Q0KI77 Q0KI77 Dmel\CG11598 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121;lipase#PC00143 DROME|FlyBase=FBgn0034641|UniProtKB=Q9W2F2 Q9W2F2 mahj PTHR13129:SF4 VPRBP PROTEIN-RELATED PROTEIN MAHJONG intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DROME|FlyBase=FBgn0264816|UniProtKB=Q9VE72 Q9VE72 koko PTHR10026:SF70 CYCLIN CYCLIN-Q enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 DROME|FlyBase=FBgn0040230|UniProtKB=Q9VUU5 Q9VUU5 dbo PTHR24412:SF491 KELCH PROTEIN KELCH-LIKE PROTEIN 20 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 DROME|FlyBase=FBgn0005355|UniProtKB=Q9VG38 Q9VG38 Su(fu) PTHR10928:SF2 SUPPRESSOR OF FUSED SUPPRESSOR OF FUSED HOMOLOG protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 Hedgehog signaling pathway#P00025>Su(fu)#P00699 DROME|FlyBase=FBgn0014861|UniProtKB=P49735 P49735 Mcm2 PTHR11630:SF44 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM2 DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;DNA damage response#GO:0006974 intracellular organelle#GO:0043229;MCM complex#GO:0042555;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0027864|UniProtKB=Q9V3I8 Q9V3I8 Ogg1 PTHR10242:SF2 8-OXOGUANINE DNA GLYCOSYLASE N-GLYCOSYLASE_DNA LYASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA N-glycosylase activity#GO:0019104;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;hydrolase activity#GO:0016787 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0037742|UniProtKB=Q9VH79 Q9VH79 Rpt3R PTHR23073:SF155 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6B isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 proteasome complex#GO:0000502;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>19S proteasome#P01494;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0037807|UniProtKB=Q9VH02 Q9VH02 Dmel\CG6293 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 DROME|FlyBase=FBgn0037130|UniProtKB=Q9VNY2 Q9VNY2 Syn1 PTHR10554:SF12 SYNTROPHIN IP02644P dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0050020|UniProtKB=Q7JQY8 Q7JQY8 p190 PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0050410|UniProtKB=Q8MLS2 Q8MLS2 Rpi PTHR11934:SF0 RIBOSE-5-PHOSPHATE ISOMERASE RIBOSE-5-PHOSPHATE ISOMERASE intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;ribose-5-phosphate isomerase activity#GO:0004751;intramolecular oxidoreductase activity#GO:0016860 purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071 DROME|FlyBase=FBgn0035194|UniProtKB=Q9W0I7 Q9W0I7 Psf1 PTHR12914:SF2 PARTNER OF SLD5 DNA REPLICATION COMPLEX GINS PROTEIN PSF1 DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;DNA strand elongation involved in DNA replication#GO:0006271;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 protein-containing complex#GO:0032991;CMG complex#GO:0071162;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;GINS complex#GO:0000811;organelle lumen#GO:0043233;chromosome#GO:0005694;DNA replication preinitiation complex#GO:0031261;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0260936|UniProtKB=Q9VRP5 Q9VRP5 scny PTHR24006:SF952 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647;regulation of programmed cell death#GO:0043067;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0286813|UniProtKB=A0A6M3Q7C8 A0A6M3Q7C8 SRPK PTHR47634:SF26 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SERINE-ARGININE PROTEIN KINASE AT 79D-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0037344|UniProtKB=Q9VNE0 Q9VNE0 Dmel\CG2926 PTHR12618:SF20 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0001281|UniProtKB=P20349 P20349 janB PTHR12258:SF5 JANUS-A/JANUS-B SEX-REGULATED PROTEIN JANUS-A-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0032401|UniProtKB=Q9VKC4 Q9VKC4 Plzf PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0000406|UniProtKB=P19967 P19967 Cyt-b5-r PTHR16740:SF1 CYTOCHROME B5-RELATED PROTEIN-RELATED CYTOCHROME B5-RELATED PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0027578|UniProtKB=Q9Y136 Q9Y136 Nepl21 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0036101|UniProtKB=Q8MPP0 Q8MPP0 NijA PTHR12316:SF17 NINJURIN-RELATED NINJURIN-A binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 programmed cell death#GO:0012501;cell adhesion#GO:0007155;cellular process#GO:0009987;cell death#GO:0008219 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0028670|UniProtKB=Q9VE75 Q9VE75 Vha100-2 PTHR11629:SF61 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;binding#GO:0005488;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002 DROME|FlyBase=FBgn0003175|UniProtKB=Q9W244 Q9W244 px PTHR40240:SF1 PLEXUS, ISOFORM A PLEXUS, ISOFORM A DROME|FlyBase=FBgn0264574|UniProtKB=Q8IRI6 Q8IRI6 Glut1 PTHR23503:SF128 SOLUTE CARRIER FAMILY 2 GLUCOSE TRANSPORTER TYPE 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 carbohydrate transmembrane transport#GO:0034219;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810;carbohydrate transport#GO:0008643 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0267363|UniProtKB=A8QI34 A8QI34 JYalpha PTHR43294:SF21 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0028622|UniProtKB=Q7K3W4 Q7K3W4 qsm PTHR47327:SF7 FI18240P1-RELATED GH08941P anatomical structure development#GO:0048856;developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653 DROME|FlyBase=FBgn0028544|UniProtKB=Q9V3Z9 Q9V3Z9 Vajk3 PTHR47771:SF12 LD27203P-RELATED HL02234P-RELATED DROME|FlyBase=FBgn0266723|UniProtKB=Q7K2Q8 Q7K2Q8 Trs31 PTHR20902:SF0 41-2 PROTEIN ANTIGEN-RELATED TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 DROME|FlyBase=FBgn0035371|UniProtKB=Q9VZX9 Q9VZX9 AhcyL1 PTHR23420:SF31 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE-LIKE 1-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0038122|UniProtKB=Q9VFY6 Q9VFY6 Cfap299 PTHR33588:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 structural protein#PC00211 DROME|FlyBase=FBgn0035084|UniProtKB=Q9W0Y0 Q9W0Y0 R5_2R:20832201..20832579 PTHR24047:SF32 FI01909P-RELATED FI01909P-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0037295|UniProtKB=A0A0B4LGN7 A0A0B4LGN7 dpr16 PTHR23279:SF21 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 11, ISOFORM B-RELATED cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253 DROME|FlyBase=FBgn0263199|UniProtKB=Q95U34 Q95U34 Galk PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220;carbohydrate kinase#PC00065;kinase#PC00137;metabolite interconversion enzyme#PC00262 Fructose galactose metabolism#P02744>Galactokinase#P02960 DROME|FlyBase=FBgn0000384|UniProtKB=P25157 P25157 cta PTHR10218:SF360 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;G protein-coupled receptor binding#GO:0001664;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein binding#GO:0005515;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;side of membrane#GO:0098552;cell projection membrane#GO:0031253;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;apical part of cell#GO:0045177;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;brush border#GO:0005903;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;brush border membrane#GO:0031526;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590 G-protein#PC00020;heterotrimeric G-protein#PC00117 DROME|FlyBase=FBgn0051913|UniProtKB=Q8IPK2 Q8IPK2 NEST:bs35c08 PTHR47148:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;NADH dehydrogenase complex assembly#GO:0010257;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 DROME|FlyBase=FBgn0002716|UniProtKB=Q7KPA5 Q7KPA5 mei-W68 PTHR10848:SF0 MEIOTIC RECOMBINATION PROTEIN SPO11 MEIOTIC RECOMBINATION PROTEIN SPO11 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;organelle organization#GO:0006996;meiotic DNA double-strand break formation#GO:0042138;response to stress#GO:0006950;cellular process#GO:0009987;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013 nucleus#GO:0005634;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 endodeoxyribonuclease#PC00093 DROME|FlyBase=FBgn0020269|UniProtKB=Q7JY80 Q7JY80 mspo PTHR11311:SF15 SPONDIN SPONDIN-2 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0029666|UniProtKB=Q9W4R7 Q9W4R7 rop-1 PTHR14202:SF0 60 KDA RIBONUCLEOPROTEIN SSA/RO RNA-BINDING PROTEIN RO60 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034046|UniProtKB=Q7K2Y9 Q7K2Y9 tun PTHR13035:SF0 PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0267824|UniProtKB=Q7JXA2 Q7JXA2 PRAS40 PTHR21844:SF2 AKT1 SUBSTRATE 1 PROTEIN PROLINE-RICH AKT1 SUBSTRATE 1 regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of TOR signaling#GO:0032006;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 CCKR signaling map#P06959>PRAS40#P07076 DROME|FlyBase=FBgn0033491|UniProtKB=Q7K1V0 Q7K1V0 Dmel\CG18011 PTHR24376:SF216 ZINC FINGER PROTEIN DRACULIN-LIKE 3 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0027087|UniProtKB=Q8IQX8 Q8IQX8 HisRS PTHR11476:SF7 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0038868|UniProtKB=Q9VDD1 Q9VDD1 Ddrgk1 PTHR48176:SF1 DDRGK DOMAIN-CONTAINING PROTEIN 1 DDRGK DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;protein binding#GO:0005515 DROME|FlyBase=FBgn0030013|UniProtKB=Q9W3I8 Q9W3I8 GIIIspla2 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 A2-type glycerophospholipase activity#GO:0004623;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689 DROME|FlyBase=FBgn0034318|UniProtKB=A1ZB48 A1ZB48 Dmel\CG14500 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0264748|UniProtKB=M9PFU4 M9PFU4 Dmel\CG44006 PTHR38926:SF5 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED F-BOX DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 DROME|FlyBase=FBgn0038218|UniProtKB=Q9VFL3 Q9VFL3 Dmel\CG14841 PTHR37161:SF2 HDC10475 AT11648P-RELATED DROME|FlyBase=FBgn0036825|UniProtKB=Q9VVU2 Q9VVU2 RpL26 PTHR11143:SF7 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER RIBOSOMAL PROTEIN L26 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0011284|UniProtKB=P41042 P41042 RpS4 PTHR11581:SF0 30S/40S RIBOSOMAL PROTEIN S4 RIBOSOMAL PROTEIN S4 Y1-RELATED structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 DROME|FlyBase=FBgn0262476|UniProtKB=A0A0B4K7V4 A0A0B4K7V4 Dmel\CG43066 PTHR11616:SF330 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 DROME|FlyBase=FBgn0011701|UniProtKB=Q7KSE4 Q7KSE4 repo PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0027491|UniProtKB=Q9V3H5 Q9V3H5 Cdk5alpha PTHR23401:SF0 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;kinase activator activity#GO:0019209;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase modulator#PC00140;kinase activator#PC00138 DROME|FlyBase=FBgn0003261|UniProtKB=P19109 P19109 Rm62 PTHR47958:SF122 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE CG14443-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 RNA helicase#PC00032 DROME|FlyBase=FBgn0038034|UniProtKB=A0A2U8U1P3 A0A2U8U1P3 Cyp9f3 PTHR24292:SF54 CYTOCHROME P450 CYTOCHROME P450 9B1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0086446|UniProtKB=Q9VIZ1 Q9VIZ1 DCTN6-p27 PTHR13072:SF0 DYNACTIN 6 DYNACTIN SUBUNIT 6 protein-containing complex binding#GO:0044877;binding#GO:0005488 mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle process#GO:0022402;cellular process#GO:0009987;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0034243|UniProtKB=Q7JXU4 Q7JXU4 Ns2 PTHR11089:SF9 GTP-BINDING PROTEIN-RELATED NUCLEOLAR GTP-BINDING PROTEIN 2 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 DROME|FlyBase=FBgn0035709|UniProtKB=Q9VRY0 Q9VRY0 eIF4E4 PTHR11960:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0035164|UniProtKB=Q9W0M5 Q9W0M5 Dmel\CG13901 PTHR31921:SF1 PROTEIN DPCD PROTEIN DPCD protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection assembly#GO:0060491;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 DROME|FlyBase=FBgn0250815|UniProtKB=Q9VRS6 Q9VRS6 Jon65Aiv PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0003510|UniProtKB=P07666 P07666 Sry-alpha PTHR18914:SF33 ALPHA CATENIN RE47911P-RELATED beta-catenin binding#GO:0008013;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;cell motility#GO:0048870;cell migration#GO:0016477 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;adherens junction#GO:0005912;anchoring junction#GO:0070161;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0053513|UniProtKB=Q9W581 Q9W581 Nmdar2 PTHR18966:SF391 IONOTROPIC GLUTAMATE RECEPTOR NMDA RECEPTOR 2, ISOFORM C transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;channel activity#GO:0015267;molecular transducer activity#GO:0060089;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;voltage-gated channel activity#GO:0022832;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;cellular process#GO:0009987;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051 cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039 DROME|FlyBase=FBgn0038432|UniProtKB=Q9VEU9 Q9VEU9 Dmel\CG14883 PTHR46320:SF1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;phospholipid metabolic process#GO:0006644;amine metabolic process#GO:0009308;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;hydrolase#PC00121 DROME|FlyBase=FBgn0029524|UniProtKB=Q9I7Z9 Q9I7Z9 BcDNA:RH59219 PTHR14365:SF2 APOPTOSIS REGULATORY PROTEIN SIVA GEO12726P1-RELATED immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune system process#GO:0002376;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716 DROME|FlyBase=FBgn0036715|UniProtKB=Q9VVG0 Q9VVG0 Cad74A PTHR24026:SF133 FAT ATYPICAL CADHERIN-RELATED CADHERIN-RELATED FAMILY MEMBER 2 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 DROME|FlyBase=FBgn0039559|UniProtKB=Q8MT36 Q8MT36 NSD PTHR22884:SF498 SET DOMAIN PROTEINS NUCLEAR RECEPTOR BINDING SET DOMAIN PROTEIN catalytic activity, acting on a protein#GO:0140096;histone H3K36 methyltransferase activity#GO:0046975;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 DROME|FlyBase=FBgn0250842|UniProtKB=A0A0B4JCT2 A0A0B4JCT2 Dmel\CG17575 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0039525|UniProtKB=Q9VB24 Q9VB24 Dmel\CG5646 PTHR45624:SF1 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SD08189P L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 intracellular transport#GO:0046907;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transmembrane transport#GO:1990542;cellular localization#GO:0051641;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;L-alpha-amino acid transmembrane transport#GO:1902475;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 transporter#PC00227 DROME|FlyBase=FBgn0028292|UniProtKB=Q9W358 Q9W358 ric8a PTHR12425:SF5 SYNEMBRYN CHAPERONE RIC-8 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053645|UniProtKB=Q4ABF6 Q4ABF6 Dmel\CG33645 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0034623|UniProtKB=Q9W2H4 Q9W2H4 Agr-like PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0037899|UniProtKB=Q9VGN9 Q9VGN9 RpL24-like PTHR10792:SF8 60S RIBOSOMAL PROTEIN L24 RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 ribosomal protein#PC00202 DROME|FlyBase=FBgn0050115|UniProtKB=A1ZBA1 A1ZBA1 GEFmeso PTHR45924:SF2 FI17866P1 FI17866P1 protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 DROME|FlyBase=FBgn0024294|UniProtKB=Q7KA66 Q7KA66 Spn43Aa PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0037061|UniProtKB=Q9VP65 Q9VP65 Trmt112 PTHR12773:SF0 UPF0315 PROTEIN-RELATED MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0035792|UniProtKB=Q9VS81 Q9VS81 Dmel\CG7548 PTHR39068:SF2 LARVAL/PUPAL CUTICLE PROTEIN H1C-LIKE PROTEIN-RELATED MIP24391P DROME|FlyBase=FBgn0010265|UniProtKB=Q03334 Q03334 RpS13 PTHR11885:SF6 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 ribosome#GO:0005840;small-subunit processome#GO:0032040;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0045473|UniProtKB=Q8INM9 Q8INM9 Gr85a PTHR21143:SF121 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 59F-RELATED neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031367|UniProtKB=Q9VQ46 Q9VQ46 c-cup PTHR10281:SF76 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED CALCUTTA CUP-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0029992|UniProtKB=Q9W3L1 Q9W3L1 Upf2 PTHR12839:SF7 NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2 REGULATOR OF NONSENSE TRANSCRIPTS 2 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0041780|UniProtKB=Q9VAQ9 Q9VAQ9 Ssl2 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0033367|UniProtKB=Q9V521 Q9V521 PPO2 PTHR11511:SF4 LARVAL STORAGE PROTEIN/PHENOLOXIDASE PHENOLOXIDASE 2-RELATED DROME|FlyBase=FBgn0030447|UniProtKB=Q9VYH3 Q9VYH3 CG2200 PTHR20842:SF0 PROTEASE S51 ALPHA-ASPARTYL DIPEPTIDASE DIPEPTIDASE E protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0035845|UniProtKB=M9PEI0 M9PEI0 Dmel\CG13675 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0039069|UniProtKB=Q9VCN5 Q9VCN5 Dmel\CG6763 PTHR10127:SF905 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0036710|UniProtKB=Q9VVF4 Q9VVF4 Dmel\CG6479 PTHR21780:SF0 TRANSMEMBRANE PROTEIN 209 TRANSMEMBRANE PROTEIN 209 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0015574|UniProtKB=Q9VIB6 Q9VIB6 alpha-Est6 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0038603|UniProtKB=A0A0B4KHC3 A0A0B4KHC3 PKD PTHR22968:SF24 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Angiogenesis#P00005>PKC#P00219;VEGF signaling pathway#P00056>PKC#P01425;EGF receptor signaling pathway#P00018>PKC#P00565 DROME|FlyBase=FBgn0085332|UniProtKB=A8JQW9 A8JQW9 Dmel\CG34303 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0033010|UniProtKB=Q8SX87 Q8SX87 Atf6 PTHR46164:SF3 ATF6, ISOFORM C ATF6, ISOFORM C sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to unfolded protein#GO:0006986;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 DROME|FlyBase=FBgn0259683|UniProtKB=Q9V9N1 Q9V9N1 Ir40a PTHR42643:SF44 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 40A transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0030685|UniProtKB=X2JDY8 X2JDY8 Graf PTHR12552:SF1 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN GRAF enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 DROME|FlyBase=FBgn0029885|UniProtKB=Q9W3Y0 Q9W3Y0 CG3224 PTHR46095:SF1 ZINC FINGER PROTEIN 593 ZINC FINGER PROTEIN 593 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0034294|UniProtKB=A1ZB24 A1ZB24 Muc55B PTHR48233:SF4 MUCIN 4B, ISOFORM B-RELATED MUCIN 4B, ISOFORM B-RELATED DROME|FlyBase=FBgn0030943|UniProtKB=Q9VWS2 Q9VWS2 Nup35 PTHR21527:SF6 NUCLEOPORIN NUP35 NUCLEOPORIN NUP35 lipid binding#GO:0008289;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;phospholipid binding#GO:0005543;binding#GO:0005488 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear pore organization#GO:0006999;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;macromolecule localization#GO:0033036;organelle organization#GO:0006996;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 transporter#PC00227 DROME|FlyBase=FBgn0011277|UniProtKB=M9PH26 M9PH26 HLH4C PTHR13864:SF10 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED HELIX-LOOP-HELIX PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0030398|UniProtKB=Q9VYM0 Q9VYM0 Cpr11B PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0024836|UniProtKB=Q9V5N8 Q9V5N8 stan PTHR24026:SF51 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN-LIKE WING POLARITY PROTEIN STAN cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon development#GO:0061564;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 DROME|FlyBase=FBgn0025639|UniProtKB=Q9W5E0 Q9W5E0 Hmt4-20 PTHR12977:SF4 SUPPRESSOR OF VARIEGATION 4-20-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B-RELATED DROME|FlyBase=FBgn0021847|UniProtKB=Q7KN74 Q7KN74 Ttc7 PTHR23083:SF476 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT DOMAIN 7, ISOFORM A protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;localization within membrane#GO:0051668;phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization#GO:0051179;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037466|UniProtKB=Q9VI54 Q9VI54 Dmel\CG1965 PTHR12214:SF0 GC-RICH SEQUENCE DNA-BINDING FACTOR LD29489P nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0031284|UniProtKB=Q9VPT7 Q9VPT7 PGAP2 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 ACYLTRANSFERASE PGAP2 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039259|UniProtKB=Q9VBZ8 Q9VBZ8 EMC6 PTHR20994:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 localization within membrane#GO:0051668;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagosome organization#GO:1905037;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;macroautophagy#GO:0016236;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;cellular component assembly#GO:0022607 membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0033814|UniProtKB=Q7JQR3 Q7JQR3 Qsox1 PTHR22897:SF8 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;extracellular structure organization#GO:0043062;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176;oxidase#PC00175 DROME|FlyBase=FBgn0030500|UniProtKB=Q9VYB1 Q9VYB1 Ndc80 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;mitotic metaphase chromosome alignment#GO:0007080;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;localization#GO:0051179;organelle fission#GO:0048285;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;attachment of spindle microtubules to kinetochore#GO:0008608;cellular process#GO:0009987;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276 membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776 transcription cofactor#PC00217 DROME|FlyBase=FBgn0267488|UniProtKB=Q9VLT3 Q9VLT3 Mcr PTHR11412:SF146 MACROGLOBULIN / COMPLEMENT LD23292P endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376 catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease inhibitor#PC00191 DROME|FlyBase=FBgn0030357|UniProtKB=H0RNK3 H0RNK3 Sclp PTHR16083:SF93 LEUCINE RICH REPEAT CONTAINING PROTEIN FI16115P1 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032688|UniProtKB=X2JAA3 X2JAA3 Dmel\CG15160 PTHR12460:SF40 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 2 RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 DROME|FlyBase=FBgn0037923|UniProtKB=E1JII8 E1JII8 CG31372 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0033864|UniProtKB=A1Z9G8 A1Z9G8 Dmel\CG18368 PTHR38758:SF1 PUTATIVE-RELATED PUTATIVE-RELATED DROME|FlyBase=FBgn0043364|UniProtKB=Q9VPQ5 Q9VPQ5 cbt PTHR23235:SF164 KRUEPPEL-LIKE TRANSCRIPTION FACTOR CABUT, ISOFORM A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0031808|UniProtKB=Q9VME3 Q9VME3 Nepl5 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0086698|UniProtKB=Q9VQ36 Q9VQ36 frtz PTHR13667:SF5 HOMOLOC-13 WD REPEAT-CONTAINING AND PLANAR CELL POLARITY EFFECTOR PROTEIN FRITZ HOMOLOG DROME|FlyBase=FBgn0034863|UniProtKB=Q9W1Q0 Q9W1Q0 SkpF PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0289579|UniProtKB=Q9VVL7 Q9VVL7 Dld PTHR22912:SF151 DISULFIDE OXIDOREDUCTASE DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 DROME|FlyBase=FBgn0010039|UniProtKB=Q9VG97 Q9VG97 GstD3 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0038595|UniProtKB=Q9VEA0 Q9VEA0 SP132 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0037200|UniProtKB=Q8IPS4 Q8IPS4 Nsun6 PTHR22807:SF34 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(72)-C(5))-METHYLTRANSFERASE NSUN6 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649 rRNA processing#GO:0006364;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;tRNA modification#GO:0006400;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0005632|UniProtKB=P55824 P55824 faf PTHR24006:SF925 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITINYL HYDROLASE 1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;cell motility#GO:0048870;cell migration#GO:0016477 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0032817|UniProtKB=Q9VIS5 Q9VIS5 Dmel\CG10631 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0034741|UniProtKB=Q9W239 Q9W239 cg4269 PTHR39945:SF1 FI14129P FI14129P DROME|FlyBase=FBgn0264695|UniProtKB=P05661 P05661 Mhc PTHR45615:SF86 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN, MUSCLE protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;system process#GO:0003008;cellular developmental process#GO:0048869;developmental process#GO:0032502;muscle contraction#GO:0006936;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0051855|UniProtKB=Q8IP73 Q8IP73 CG6537 PTHR31879:SF2 DET1- AND DDB1-ASSOCIATED PROTEIN 1 DET1- AND DDB1-ASSOCIATED PROTEIN 1 regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of proteasomal protein catabolic process#GO:1901800 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 DROME|FlyBase=FBgn0016641|UniProtKB=Q9W2F3 Q9W2F3 PTP-ER PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DROME|FlyBase=FBgn0262111|UniProtKB=Q0KHR2 Q0KHR2 f PTHR24153:SF8 ESPIN FORKED, ISOFORM F binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0038926|UniProtKB=Q9VD53 Q9VD53 Dmel\CG13409 PTHR31918:SF2 TRANSMEMBRANE PROTEIN 181 TRANSMEMBRANE PROTEIN 181 positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of protein secretion#GO:0050714;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of protein secretion#GO:0050708;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of protein transport#GO:0051223;regulation of cell communication#GO:0010646;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of secretion by cell#GO:1903530 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037798|UniProtKB=Q0KI91 Q0KI91 Dmel\CG12817 PTHR23104:SF1 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 DROME|FlyBase=FBgn0030575|UniProtKB=Q9VY24 Q9VY24 anon-EST:Posey66 PTHR10696:SF58 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED GAMMA-BUTYROBETAINE DIOXYGENASE-RELATED dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biosynthetic process#GO:0009058;carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydroxylase#PC00122 DROME|FlyBase=FBgn0031702|UniProtKB=Q7K3S3 Q7K3S3 fusl PTHR35270:SF3 FUSELESS, ISOFORM A FUSELESS, ISOFORM A neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cell maturation#GO:0048469;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;developmental process#GO:0032502;neuromuscular synaptic transmission#GO:0007274;nervous system development#GO:0007399;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental maturation#GO:0021700;cellular process#GO:0009987;synaptic signaling#GO:0099536;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;generation of neurons#GO:0048699;trans-synaptic signaling#GO:0099537;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;cell differentiation#GO:0030154;anatomical structure maturation#GO:0071695;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590 DROME|FlyBase=FBgn0261396|UniProtKB=P25161 P25161 Rpn3 PTHR10758:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541 protein modifying enzyme#PC00260;protease#PC00190 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0030538|UniProtKB=Q9VY63 Q9VY63 betaNACtes1 PTHR10351:SF23 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0051869|UniProtKB=Q9VKQ0 Q9VKQ0 CG18499 PTHR46698:SF9 CROSSVEINLESS 2 TENECTIN ISOFORM 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0032181|UniProtKB=Q9VL41 Q9VL41 Dmel\CG13133 PTHR45640:SF40 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN 22-RELATED gene expression#GO:0010467;protein maturation#GO:0051604;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;response to heat#GO:0009408;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;protein refolding#GO:0042026 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 chaperone#PC00072 DROME|FlyBase=FBgn0022027|UniProtKB=Q7JXV9 Q7JXV9 Vps25 PTHR13149:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25 protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;protein transport#GO:0015031;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0036560|UniProtKB=Q9VUX4 Q9VUX4 Dmel\CG5895 PTHR13593:SF157 FAMILY NOT NAMED RE10370P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 DROME|FlyBase=FBgn0005664|UniProtKB=Q9VKE2 Q9VKE2 Crys PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028836|UniProtKB=Q9V4S8 Q9V4S8 CSN7 PTHR15350:SF5 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DROME|FlyBase=FBgn0041710|UniProtKB=Q9VG09 Q9VG09 yellow-f PTHR10009:SF10 PROTEIN YELLOW-RELATED L-DOPACHROME TAUTOMERASE YELLOW-F-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053673|UniProtKB=Q4ABI5 Q4ABI5 Dmel\CG33673 PTHR23291:SF131 BAX INHIBITOR-RELATED TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0014022|UniProtKB=Q27411 Q27411 Rlb1 PTHR23325:SF1 SERUM RESPONSE FACTOR-BINDING SERUM RESPONSE FACTOR-BINDING PROTEIN 1 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0086361|UniProtKB=Q961C5 Q961C5 alph PTHR47992:SF257 PROTEIN PHOSPHATASE ALPHABET, ISOFORM E phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DPP signaling pathway#P06213>PPM1A#P06289;Activin beta signaling pathway#P06210>PPM1A#P06237;MYO signaling pathway#P06215>PPM1A#P06317;SCW signaling pathway#P06216>PPM1A#P06332;BMP/activin signaling pathway-drosophila#P06211>PPM1A#P06247;GBB signaling pathway#P06214>PPM1A#P06296;ALP23B signaling pathway#P06209>PPM1A#P06226;DPP-SCW signaling pathway#P06212>PPM1A#P06261 DROME|FlyBase=FBgn0039645|UniProtKB=Q9VAN4 Q9VAN4 Dmel\CG11898 PTHR24223:SF324 ATP-BINDING CASSETTE SUB-FAMILY C LD17001P establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0036749|UniProtKB=Q9VVK1 Q9VVK1 Dmel\CG7460 PTHR10742:SF398 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidase#PC00175 DROME|FlyBase=FBgn0031238|UniProtKB=Q9VPM1 Q9VPM1 Dus1 PTHR11082:SF5 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA processing factor#PC00147 DROME|FlyBase=FBgn0263143|UniProtKB=Q9VCU7 Q9VCU7 vret PTHR22948:SF84 TUDOR DOMAIN CONTAINING PROTEIN FI02030P-RELATED biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;cell maturation#GO:0048469;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;pattern specification process#GO:0007389;piRNA processing#GO:0034587;RNA processing#GO:0006396;oogenesis#GO:0048477;embryo development#GO:0009790;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;embryonic pattern specification#GO:0009880;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anterior/posterior axis specification#GO:0009948;metabolic process#GO:0008152;anterior/posterior pattern specification#GO:0009952;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036659|UniProtKB=Q9VV98 Q9VV98 Dmel\CG9701 PTHR10353:SF36 GLYCOSYL HYDROLASE CYTOSOLIC BETA-GLUCOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;beta-glucosidase activity#GO:0008422;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycosidase#PC00110;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039896|UniProtKB=Q9V4C0 Q9V4C0 yellow-h PTHR10009:SF13 PROTEIN YELLOW-RELATED DOPAMINECHROME TAUTOMERASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0031607|UniProtKB=Q8SXG7 Q8SXG7 Secp43 PTHR47640:SF81 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DROME|FlyBase=FBgn0025632|UniProtKB=Q9W533 Q9W533 EG:22E5.10 PTHR24228:SF59 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR NEUROPEPTIDE RECEPTOR 15 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0050203|UniProtKB=Q3ZAL6 Q3ZAL6 CG17740 PTHR11311:SF16 SPONDIN SPONDIN-1 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0021742|UniProtKB=Q9VZ44 Q9VZ44 C901 PTHR24044:SF420 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN-RELATED intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 DROME|FlyBase=FBgn0035464|UniProtKB=Q9VZM5 Q9VZM5 PIG-B PTHR22760:SF4 GLYCOSYLTRANSFERASE GPI ALPHA-1,2-MANNOSYLTRANSFERASE 3 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0050363|UniProtKB=A1Z7D9 A1Z7D9 cola PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0033971|UniProtKB=A0A0B4KEQ7 A0A0B4KEQ7 Dmel\CG10209 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE DROME|FlyBase=FBgn0040777|UniProtKB=Q7KGU6 Q7KGU6 dmCG14767 PTHR12479:SF10 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of membrane permeability#GO:0090559 membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 DROME|FlyBase=FBgn0033397|UniProtKB=Q9V559 Q9V559 Cyp4p3 PTHR24291:SF105 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4P1-RELATED oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034059|UniProtKB=A1ZA77 A1ZA77 Tmem208 PTHR13505:SF7 TRANSMEMBRANE PROTEIN 208 TRANSMEMBRANE PROTEIN 208 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 DROME|FlyBase=FBgn0033467|UniProtKB=Q4QQ01 Q4QQ01 Pdrg1 PTHR21162:SF0 P53 AND DNA DAMAGE-REGULATED PROTEIN P53 AND DNA DAMAGE-REGULATED PROTEIN 1 DROME|FlyBase=FBgn0036621|UniProtKB=Q9VV48 Q9VV48 roq PTHR13139:SF54 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN RING-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;nucleic acid binding#GO:0003676;acyltransferase activity#GO:0016746;mRNA binding#GO:0003729;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;positive regulation of mRNA catabolic process#GO:0061014;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA catabolic process#GO:0006401;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;protein ubiquitination#GO:0016567;positive regulation of macromolecule metabolic process#GO:0010604 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0034091|UniProtKB=A8DYF7 A8DYF7 mrj PTHR43948:SF10 DNAJ HOMOLOG SUBFAMILY B MRJ, ISOFORM E protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0001196|UniProtKB=P84051 P84051 His2A PTHR23430:SF390 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558 organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0046689|UniProtKB=P83104 P83104 Takl1 PTHR46716:SF1 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;JNK cascade#GO:0007254;positive regulation of response to stimulus#GO:0048584;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of canonical NF-kappaB signal transduction#GO:0043123 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;TGF-beta signaling pathway#P00052>TAK#P01285;Interleukin signaling pathway#P00036>MEK#P00984;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Gonadotropin-releasing hormone receptor pathway#P06664>TAK1#P06799;p38 MAPK pathway#P05918>TAK1#P06037;Toll receptor signaling pathway#P00054>TAK1#P01370 DROME|FlyBase=FBgn0030960|UniProtKB=Q9VWQ1 Q9VWQ1 Atg101 PTHR13292:SF0 AUTOPHAGY-RELATED PROTEIN 101 AUTOPHAGY-RELATED PROTEIN 101 kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;catabolic process#GO:0009056;organelle assembly#GO:0070925;metabolic process#GO:0008152;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554 DROME|FlyBase=FBgn0017550|UniProtKB=Q94547 Q94547 Rga PTHR23326:SF35 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;CCR4-NOT complex#GO:0030014;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0013435|UniProtKB=A1Z840 A1Z840 Cdc2rk PTHR24056:SF508 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 10 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 mitotic cell cycle phase transition#GO:0044772;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;mitotic cell cycle process#GO:1903047;regulation of cell cycle G2/M phase transition#GO:1902749;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0015245|UniProtKB=O02649 O02649 Hsp60A PTHR45633:SF53 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN HOMOLOG 1, MITOCHONDRIAL-RELATED protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;mitochondrial protein import pathway#GO:7770058;transport#GO:0006810;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;cellular response to stimulus#GO:0051716;cell death#GO:0008219;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;localization#GO:0051179;protein metabolic process#GO:0019538;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;apoptotic process#GO:0006915;cellular component organization#GO:0016043;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;cellular localization#GO:0051641 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0030956|UniProtKB=Q9VWQ6 Q9VWQ6 Dmel\CG18259 PTHR19965:SF96 RNA AND EXPORT FACTOR BINDING PROTEIN POLYMERASE DELTA-INTERACTING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;localization#GO:0051179;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039463|UniProtKB=Q9VBA1 Q9VBA1 Spag1 PTHR45984:SF1 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG SPAG1 AXONEMAL DYNEIN ASSEMBLY FACTOR heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0030823|UniProtKB=Q9VX74 Q9VX74 TTLL1A PTHR12241:SF31 TUBULIN POLYGLUTAMYLASE POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1 protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874 cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0033698|UniProtKB=Q9V677 Q9V677 CG8858 PTHR23346:SF19 TRANSLATIONAL ACTIVATOR GCN1-RELATED PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0027795|UniProtKB=Q9W593 Q9W593 EG:BACN32G11.2 PTHR22667:SF0 AT01380P-RELATED AT01380P-RELATED DROME|FlyBase=FBgn0034897|UniProtKB=Q9W1K5 Q9W1K5 Sesn PTHR12474:SF0 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN HOMOLOG oxidoreductase activity#GO:0016491;amino acid binding#GO:0016597;catalytic activity#GO:0003824;cation binding#GO:0043169;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;positive regulation of macroautophagy#GO:0016239;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;response to chemical#GO:0042221;cellular response to amino acid starvation#GO:0034198;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;response to acid chemical#GO:0001101;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262 oxidoreductase#PC00176;peroxidase#PC00180 DROME|FlyBase=FBgn0039698|UniProtKB=Q9VAG9 Q9VAG9 Dmel\CG7789 PTHR43028:SF5 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0035004|UniProtKB=Q9W173 Q9W173 Pgam5-2 PTHR20935:SF0 PHOSPHOGLYCERATE MUTASE-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 positive regulation of organelle organization#GO:0010638;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cellular component organization#GO:0051130;positive regulation of developmental process#GO:0051094;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;biological regulation#GO:0065007;positive regulation of mitochondrial fission#GO:0090141;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of organelle organization#GO:0033043 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 mutase#PC00160;isomerase#PC00135 DROME|FlyBase=FBgn0036489|UniProtKB=Q9VUM3 Q9VUM3 Dmel\CG7011 PTHR10984:SF85 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034489|UniProtKB=Q86LH3 Q86LH3 ppk6 PTHR11690:SF263 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 6-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0034543|UniProtKB=Q9V968 Q9V968 galla-1 PTHR12377:SF2 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2A macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0033973|UniProtKB=Q7K3N1 Q7K3N1 HPS1 PTHR12761:SF2 HERMANSKY-PUDLAK SYNDROME PROTEIN 1 GH27401P GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0035160|UniProtKB=Q9W0N1 Q9W0N1 hng3 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0034728|UniProtKB=Q9W252 Q9W252 rad50 PTHR18867:SF12 RAD50 DNA REPAIR PROTEIN RAD50 single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;RNA-templated DNA biosynthetic process#GO:0006278;DNA repair#GO:0006281;reproductive process#GO:0022414;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;telomere organization#GO:0032200;sexual reproduction#GO:0019953;mitotic recombination#GO:0006312;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;organelle organization#GO:0006996;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;response to stimulus#GO:0050896;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794 DROME|FlyBase=FBgn0259937|UniProtKB=O44081 O44081 Nop60B PTHR23127:SF0 CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;snRNA processing#GO:0016180;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;mRNA modification#GO:0016556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077;centromere DNA-binding protein#PC00071 DROME|FlyBase=FBgn0004132|UniProtKB=Q8T9B6 Q8T9B6 boca PTHR17600:SF2 MESODERM DEVELOPMENT CANDIDATE 2 LRP CHAPERONE MESD DROME|FlyBase=FBgn0036757|UniProtKB=Q9VVL1 Q9VVL1 Ir75a PTHR42643:SF32 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 31A, ISOFORM C-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0011556|UniProtKB=P42280 P42280 zetaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0031493|UniProtKB=Q9VQK7 Q9VQK7 Sf3b2 PTHR12785:SF19 SPLICING FACTOR 3B SPLICING FACTOR 3B SUBUNIT 2 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0023509|UniProtKB=Q9W542 Q9W542 mip130 PTHR21689:SF2 LIN-9 PROTEIN LIN-9 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0027082|UniProtKB=Q9VZY9 Q9VZY9 ProRS-m PTHR42753:SF10 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0259111|UniProtKB=Q8IPI3 Q8IPI3 Ndae1 PTHR11453:SF36 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034068|UniProtKB=Q7JUP3 Q7JUP3 casp PTHR23322:SF107 FAS-ASSOCIATED PROTEIN CASPAR, ISOFORM A ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 FAS signaling pathway#P00020>FAF1#P00609 DROME|FlyBase=FBgn0023550|UniProtKB=Q9W508 Q9W508 FarO PTHR11011:SF130 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0030541|UniProtKB=Q8IR58 Q8IR58 Dmel\CG11584 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0031855|UniProtKB=Q9VM90 Q9VM90 meng PTHR24359:SF26 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE_THREONINE-PROTEIN KINASE MENG-PO protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0034029|UniProtKB=A1ZA22 A1ZA22 eIF2Bgamma PTHR45989:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT GAMMA molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;translation factor activity#GO:0180051;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 DROME|FlyBase=FBgn0032477|UniProtKB=Q9VK30 Q9VK30 Alg7 PTHR10571:SF0 UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0286198|UniProtKB=Q9VLX0 Q9VLX0 LKRSDH PTHR11133:SF28 SACCHAROPINE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 DROME|FlyBase=FBgn0035872|UniProtKB=Q9VSH4 Q9VSH4 Cpsf6 PTHR23204:SF10 CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031227|UniProtKB=Q9VPK7 Q9VPK7 Pus10 PTHR21568:SF0 TRNA PSEUDOURIDINE SYNTHASE PUS10 TRNA PSEUDOURIDINE SYNTHASE PUS10 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;primary miRNA processing#GO:0031053;tRNA processing#GO:0008033;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;tRNA modification#GO:0006400 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034884|UniProtKB=Q9W1M2 Q9W1M2 Eglp3 PTHR19139:SF270 AQUAPORIN TRANSPORTER ENTOMOGLYCEROPORIN 1-RELATED channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;fluid transport#GO:0042044;localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;apical part of cell#GO:0045177 transporter#PC00227 DROME|FlyBase=FBgn0030177|UniProtKB=Q9W2Y4 Q9W2Y4 Dmel\CG2972 PTHR12814:SF2 RNA-BINDING PROTEIN NOB1 RNA-BINDING PROTEIN NOB1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904 DROME|FlyBase=FBgn0085414|UniProtKB=A1Z6H9 A1Z6H9 dpr12 PTHR23279:SF45 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 12, ISOFORM C cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020 DROME|FlyBase=FBgn0000244|UniProtKB=Q9VHC3 Q9VHC3 by PTHR45734:SF10 TENSIN BLISTERY, ISOFORM A cell junction#GO:0030054;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0015568|UniProtKB=Q9VIC3 Q9VIC3 alpha-Est1 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0028550|UniProtKB=Q9XZS8 Q9XZS8 Atf3 PTHR23351:SF24 FOS TRANSCRIPTION FACTOR-RELATED ACTIVATING TRANSCRIPTION FACTOR 3-RELATED basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0036662|UniProtKB=A0A4D6K3L8 A0A4D6K3L8 Dmel\CG9706 PTHR12778:SF9 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED ACETYL-COENZYME A TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0016126|UniProtKB=Q7JMV3 Q7JMV3 CaMKI PTHR24347:SF456 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0086917|UniProtKB=A8Y592 A8Y592 spok PTHR24303:SF31 HEME-BINDING MONOOXYGENASE FAMILY CYTOCHROME P450 307A1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0034322|UniProtKB=A1ZB54 A1ZB54 Dmel\CG18536 PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0036410|UniProtKB=Q9VUC9 Q9VUC9 lincRNA.S5087 PTHR11511:SF5 LARVAL STORAGE PROTEIN/PHENOLOXIDASE FAT-BODY PROTEIN 1-RELATED DROME|FlyBase=FBgn0039788|UniProtKB=Q9VA54 Q9VA54 Rpt6R PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0037001|UniProtKB=Q9VPE2 Q9VPE2 ND-39 PTHR12126:SF11 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL protein-containing complex binding#GO:0044877;binding#GO:0005488 ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 DROME|FlyBase=FBgn0262580|UniProtKB=M9NDR1 M9NDR1 Dmel\CG43120 PTHR24410:SF51 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN-RELATED defense/immunity protein#PC00090 DROME|FlyBase=FBgn0260499|UniProtKB=B5A5T4 B5A5T4 qvr PTHR33562:SF27 ATILLA, ISOFORM B-RELATED-RELATED FI02817P-RELATED DROME|FlyBase=FBgn0033154|UniProtKB=A1Z6W6 A1Z6W6 Dmel\CG1850 PTHR31750:SF31 PROTEIN STAY-GREEN 1, CHLOROPLASTIC-RELATED LP06106P DROME|FlyBase=FBgn0031518|UniProtKB=Q8IQ00 Q8IQ00 Dmel\CG3277 PTHR24416:SF594 TYROSINE-PROTEIN KINASE RECEPTOR PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0052626|UniProtKB=X2JEY5 X2JEY5 AMPdeam PTHR11359:SF0 AMP DEAMINASE AMP DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987 deaminase#PC00088 Purine metabolism#P02769>5'-AMP Deaminase#P03117 DROME|FlyBase=FBgn0027563|UniProtKB=Q9Y122 Q9Y122 Dmel\CG9631 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0025832|UniProtKB=Q7K7A9 Q7K7A9 Fen1 PTHR11081:SF81 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE 1 catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;metal ion binding#GO:0046872;DNA endonuclease activity#GO:0004520;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;binding#GO:0005488;exonuclease activity#GO:0004527;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;magnesium ion binding#GO:0000287;cation binding#GO:0043169;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0039139|UniProtKB=Q9VCE6 Q9VCE6 Mettl3 PTHR12829:SF7 N6-ADENOSINE-METHYLTRANSFERASE N(6)-ADENOSINE-METHYLTRANSFERASE CATALYTIC SUBUNIT METTL3 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA modification#GO:0016556;cellular process#GO:0009987;mRNA metabolic process#GO:0016071;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0053337|UniProtKB=Q7KS40 Q7KS40 Dmel\CG33337 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0031971|UniProtKB=Q9VLU6 Q9VLU6 Sirup PTHR28524:SF3 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL chaperone#PC00072 DROME|FlyBase=FBgn0034067|UniProtKB=Q8MSU3 Q8MSU3 sdr2 PTHR45828:SF38 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE FERRIC REDUCTASE 1 catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on metal ions#GO:0016722 cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0000180|UniProtKB=P23645 P23645 bib PTHR19139:SF268 AQUAPORIN TRANSPORTER NEUROGENIC PROTEIN BIG BRAIN channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;passive transmembrane transporter activity#GO:0022803 localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0036848|UniProtKB=Q9VVW8 Q9VVW8 Naxd PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 metabolic process#GO:0008152;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0036624|UniProtKB=Q9VV52 Q9VV52 RAF2 PTHR10237:SF15 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0037702|UniProtKB=Q6AWD5 Q6AWD5 Sgip1 PTHR23065:SF15 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 AT02057P import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;protein-containing complex assembly#GO:0065003 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated vesicle#GO:0030136;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0035528|UniProtKB=Q9VZE2 Q9VZE2 Dmel\CG15012 PTHR13180:SF4 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50A transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 DROME|FlyBase=FBgn0036940|UniProtKB=Q9VW81 Q9VW81 obst-J PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0034948|UniProtKB=Q9W1E4 Q9W1E4 PPP1R15 PTHR16489:SF12 GH11727P GH11727P enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 DROME|FlyBase=FBgn0050051|UniProtKB=A1Z903 A1Z903 Tmem18 PTHR22593:SF2 TRANSMEMBRANE PROTEIN 18 TRANSMEMBRANE PROTEIN 18 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0037167|UniProtKB=Q9VNT8 Q9VNT8 WUN-like PTHR10165:SF103 LIPID PHOSPHATE PHOSPHATASE FI04477P-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;dephosphorylation#GO:0016311;cell communication#GO:0007154;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0034210|UniProtKB=Q8MRA9 Q8MRA9 Camp PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A DROME|FlyBase=FBgn0020258|UniProtKB=Q7KT94 Q7KT94 ppk PTHR11690:SF288 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0032243|UniProtKB=Q9VKW4 Q9VKW4 Klp31E PTHR24115:SF929 KINESIN-RELATED KINESIN-LIKE PROTEIN AT 31E, ISOFORM A catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0037836|UniProtKB=Q9VGW4 Q9VGW4 Dmel\CG14692 PTHR37001:SF5 PHOSPHORYN, PUTATIVE-RELATED-RELATED RIIA DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0039789|UniProtKB=Q9I7H4 Q9I7H4 Dmel\CG9717 PTHR11814:SF231 SULFATE TRANSPORTER RE02508P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0053454|UniProtKB=A1ZBI1 A1ZBI1 Dmel\CG33454 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0040334|UniProtKB=Q9W4X6 Q9W4X6 Tsp3A PTHR19282:SF489 TETRASPANIN TETRASPANIN-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0027780|UniProtKB=Q9VLL0 Q9VLL0 Aasdh PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME metabolite interconversion enzyme#PC00262;ligase#PC00142 DROME|FlyBase=FBgn0045483|UniProtKB=Q9W1V0 Q9W1V0 Gr59a PTHR21143:SF132 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 33A-RELATED dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037324|UniProtKB=Q9VNB5 Q9VNB5 Orco PTHR21137:SF9 ODORANT RECEPTOR ODORANT RECEPTOR CORECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0033784|UniProtKB=Q8T8S1 Q8T8S1 SCCRO3 PTHR12281:SF31 RP42 RELATED DCN1-LIKE PROTEIN 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515 positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of protein modification process#GO:0031399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0051661|UniProtKB=Q9VQ14 Q9VQ14 CG10872 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987 aspartic protease#PC00053;protease#PC00190 DROME|FlyBase=FBgn0011672|UniProtKB=P49283 P49283 Mvl PTHR11706:SF113 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER PROTEIN MALVOLIO transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;iron ion transmembrane transporter activity#GO:0005381 establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;iron ion transmembrane transport#GO:0034755;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;iron ion transport#GO:0006826;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0037329|UniProtKB=Q8IPQ6 Q8IPQ6 POLDIP2 PTHR14289:SF16 F-BOX ONLY PROTEIN 3 POLYMERASE DELTA-INTERACTING PROTEIN 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;nucleoid#GO:0009295;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0040697|UniProtKB=Q9VZG8 Q9VZG8 Teh3 PTHR12335:SF7 TIPE PROTEIN TEMPERATURE-INDUCED PARALYTIC E RT03134P molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 regulation of biological process#GO:0050789;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0035718|UniProtKB=Q9VRZ3 Q9VRZ3 Dmel\CG14820 PTHR11705:SF123 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0038016|UniProtKB=Q9VGA4 Q9VGA4 MBD-R2 PTHR15856:SF51 PHD FINGER PROTEIN 20-RELATED PROTEIN MBD-R2 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;chromatin#GO:0000785;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248 DROME|FlyBase=FBgn0036685|UniProtKB=Q9VVC8 Q9VVC8 Ccdc6 PTHR15276:SF0 H4 D10S170 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 6 DROME|FlyBase=FBgn0042207|UniProtKB=Q9VG50 Q9VG50 CG12294 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 hydrolase#PC00121;lipase#PC00143 DROME|FlyBase=FBgn0051080|UniProtKB=Q9VBD4 Q9VBD4 TwdlH PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 DROME|FlyBase=FBgn0034196|UniProtKB=A1ZAQ6 A1ZAQ6 Dmel\CG15605 PTHR12292:SF9 RWD DOMAIN-CONTAINING PROTEIN RWD DOMAIN-CONTAINING PROTEIN 1 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;intracellular receptor signaling pathway#GO:0030522;signaling#GO:0023052;response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to hormone#GO:0009725;cellular process#GO:0009987;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;signal transduction#GO:0007165;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;nuclear receptor-mediated signaling pathway#GO:0141193;biological regulation#GO:0065007;cellular response to steroid hormone stimulus#GO:0071383 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0050339|UniProtKB=Q8SXR4 Q8SXR4 Dmel\CG30339 PTHR10174:SF216 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN-RELATED anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0030291|UniProtKB=Q9VZ02 Q9VZ02 BcDNA:RE11532 PTHR28366:SF1 CHROMOSOME 1 OPEN READING FRAME 131 40S SMALL SUBUNIT PROCESSOME ASSEMBLY FACTOR 1 DROME|FlyBase=FBgn0025743|UniProtKB=Q9VXE5 Q9VXE5 mbt PTHR48015:SF4 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK MBT protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to nutrient levels#GO:0031667;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 DROME|FlyBase=FBgn0038925|UniProtKB=Q9VD55 Q9VD55 Cchl PTHR12743:SF0 CYTOCHROME C1 HEME LYASE HOLOCYTOCHROME C-TYPE SYNTHASE catalytic activity, acting on a protein#GO:0140096;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 lyase#PC00144 DROME|FlyBase=FBgn0025807|UniProtKB=O96533 O96533 Rad9 PTHR15237:SF0 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9 signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular response to radiation#GO:0071478;response to stimulus#GO:0050896;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;response to ionizing radiation#GO:0010212;signal transduction in response to DNA damage#GO:0042770;response to abiotic stimulus#GO:0009628;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cellular response to stress#GO:0033554;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;DNA replication checkpoint signaling#GO:0000076;cellular response to abiotic stimulus#GO:0071214;negative regulation of cell cycle#GO:0045786;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;regulation of mitotic cell cycle#GO:0007346;response to radiation#GO:0009314;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 exodeoxyribonuclease#PC00098 DROME|FlyBase=FBgn0263598|UniProtKB=Q27331 Q27331 Vha68-2 PTHR43607:SF10 V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A H(+)-TRANSPORTING TWO-SECTOR ATPASE monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829 transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773 ATP synthase#PC00002 DROME|FlyBase=FBgn0035023|UniProtKB=Q0E8W5 Q0E8W5 ITP PTHR35981:SF2 ION TRANSPORT PEPTIDE, ISOFORM C ION TRANSPORT PEPTIDE, ISOFORM C rhythmic process#GO:0048511;circadian rhythm#GO:0007623 DROME|FlyBase=FBgn0051549|UniProtKB=Q8SX57 Q8SX57 CG11005 PTHR43975:SF6 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED DROME|FlyBase=FBgn0032847|UniProtKB=Q9VIP1 Q9VIP1 Taf13 PTHR11380:SF17 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259 DROME|FlyBase=FBgn0031002|UniProtKB=Q9VWK0 Q9VWK0 Dmel\CG14196 PTHR11360:SF8 MONOCARBOXYLATE TRANSPORTER BCDNA.LD28120-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0030667|UniProtKB=Q9VXS2 Q9VXS2 Dmel\CG15599 PTHR23246:SF13 NEW-GLUE PROTEIN GH12359P DROME|FlyBase=FBgn0052392|UniProtKB=Q9VRY7 Q9VRY7 Rsph3 PTHR21648:SF0 FLAGELLAR RADIAL SPOKE PROTEIN 3 RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 DROME|FlyBase=FBgn0034753|UniProtKB=Q9W227 Q9W227 Dmel\CG2852 PTHR11071:SF581 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0267487|UniProtKB=Q9W0G1 Q9W0G1 Ptp61F PTHR46047:SF3 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DROME|FlyBase=FBgn0033238|UniProtKB=Q7K049 Q7K049 azot PTHR23050:SF547 CALCIUM BINDING PROTEIN AT10229P-RELATED calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0031299|UniProtKB=Q9VPW3 Q9VPW3 anon-WO0257455.15 PTHR24343:SF0 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE NIM1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0038286|UniProtKB=Q9VFD5 Q9VFD5 CG6966 PTHR24173:SF93 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG CG6966 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0045035|UniProtKB=Q5EAK6 Q5EAK6 tefu PTHR11139:SF72 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE ATM catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to stress#GO:0006950;regulation of telomere maintenance via telomere lengthening#GO:1904356;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular response to abiotic stimulus#GO:0071214;double-strand break repair#GO:0006302;response to abiotic stimulus#GO:0009628;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;response to ionizing radiation#GO:0010212;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;positive regulation of cellular component organization#GO:0051130;cellular response to stress#GO:0033554;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to radiation#GO:0009314;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of chromosome organization#GO:0033044;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;regulation of telomere maintenance#GO:0032204;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of DNA metabolic process#GO:0051054;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036426|UniProtKB=Q9VUE9 Q9VUE9 Dmel\CG9592 PTHR31996:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA22 monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;biological regulation#GO:0065007 cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0035923|UniProtKB=Q9VSP0 Q9VSP0 Dmel\CG6511 PTHR15000:SF1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 DROME|FlyBase=FBgn0038878|UniProtKB=Q9VDC0 Q9VDC0 FOHSDR PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0038818|UniProtKB=Q8T062 Q8T062 Nep4 PTHR11733:SF248 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-4 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0039157|UniProtKB=Q4AB27 Q4AB27 Myo95E PTHR13140:SF802 MYOSIN MYOSIN 95E, ISOFORM E cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 transport#GO:0006810;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based movement#GO:0030048;cellular process#GO:0009987;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0037369|UniProtKB=Q9VNH2 Q9VNH2 Dmel\CG2100 PTHR46173:SF1 CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;tRNA 3'-end processing#GO:0042780;mitochondrial RNA 3'-end processing#GO:0000965 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0036813|UniProtKB=Q9VVS6 Q9VVS6 Atg3 PTHR12866:SF2 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787 metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;macromolecule catabolic process#GO:0009057;generation of precursor metabolites and energy#GO:0006091;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;autophagosome assembly#GO:0000045;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;glycogen catabolic process#GO:0005980;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;carbohydrate catabolic process#GO:0016052;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251 phagophore assembly site#GO:0000407;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0036899|UniProtKB=Q9VW27 Q9VW27 tey PTHR13459:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238 DROME|FlyBase=FBgn0034510|UniProtKB=A1ZBU4 A1ZBU4 Dmel\CG13426 PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum#GO:0005791;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 primary active transporter#PC00068 DROME|FlyBase=FBgn0025865|UniProtKB=Q9VDF4 Q9VDF4 Cortactin PTHR10829:SF23 CORTACTIN AND DREBRIN CORTACTIN, ISOFORM A actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell migration#GO:0016477;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;supramolecular fiber#GO:0099512;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0038845|UniProtKB=Q9VDG4 Q9VDG4 Alp5 PTHR11596:SF85 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0052484|UniProtKB=Q9VZW0 Q9VZW0 Sk2 PTHR12358:SF112 SPHINGOSINE KINASE SPHINGOSINE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 sphingoid biosynthetic process#GO:0046520;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 DROME|FlyBase=FBgn0015572|UniProtKB=Q9VIC0 Q9VIC0 alpha-Est4 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0004860|UniProtKB=Q9W523 Q9W523 ph-d PTHR12247:SF138 POLYCOMB GROUP PROTEIN L(3)MBT INTERACTOR IN OVARIAN SOMATIC CELLS, ISOFORM A-RELATED chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0052304|UniProtKB=Q8IRF4 Q8IRF4 obst-I PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;carbohydrate derivative binding#GO:0097367 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0031697|UniProtKB=Q9VMS3 Q9VMS3 d4ST1 PTHR12137:SF30 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 transferase#PC00220 DROME|FlyBase=FBgn0032447|UniProtKB=X2JDZ1 X2JDZ1 PICK1 PTHR12141:SF1 ARFAPTIN-RELATED PRKCA-BINDING PROTEIN molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of receptor-mediated endocytosis#GO:0048259;neuron projection organization#GO:0106027;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein transport#GO:0015031;cellular localization#GO:0051641;receptor clustering#GO:0043113;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of biological process#GO:0048518;dendritic spine organization#GO:0097061;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component organization or biogenesis#GO:0071840;regulation of endocytosis#GO:0030100;intracellular protein transport#GO:0006886;postsynapse organization#GO:0099173;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;localization within membrane#GO:0051668;synapse organization#GO:0050808;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of endocytosis#GO:0045807;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;postsynaptic specialization#GO:0099572;transport vesicle#GO:0030133;endomembrane system#GO:0012505;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;cell junction#GO:0030054;trans-Golgi network membrane#GO:0032588;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005 vesicle coat protein#PC00235 Ionotropic glutamate receptor pathway#P00037>PICK#P01012 DROME|FlyBase=FBgn0030615|UniProtKB=Q9VXY0 Q9VXY0 Cyp4s3 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0283682|UniProtKB=Q9VKK1 Q9VKK1 Ge-1 PTHR15598:SF5 ENHANCER OF MRNA-DECAPPING PROTEIN 4 ENHANCER OF MRNA-DECAPPING PROTEIN 4 molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;RNA decapping#GO:0110154;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 mRNA capping factor#PC00145 DROME|FlyBase=FBgn0039028|UniProtKB=Q9VCT6 Q9VCT6 Dmel\CG13840 PTHR47771:SF6 LD27203P-RELATED LP03545P DROME|FlyBase=FBgn0002887|UniProtKB=Q4U2Q5 Q4U2Q5 mus201 PTHR11081:SF76 FLAP ENDONUCLEASE FAMILY MEMBER FI23547P1 endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 DROME|FlyBase=FBgn0028692|UniProtKB=Q9V3P6 Q9V3P6 Rpn2 PTHR10943:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endopeptidase complex#GO:1905369;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;proteasome complex#GO:0000502;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0038881|UniProtKB=Q9VDB7 Q9VDB7 aus PTHR22255:SF10 LP06548P ARGUS, ISOFORM A autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;transport#GO:0006810;metabolic process#GO:0008152;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179 DROME|FlyBase=FBgn0003388|UniProtKB=Q9VUF8 Q9VUF8 shd PTHR24305:SF166 CYTOCHROME P450 CYTOCHROME P450 302A1, MITOCHONDRIAL-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0035825|UniProtKB=Q9VSB9 Q9VSB9 Tmem43 PTHR13416:SF2 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 43 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 DROME|FlyBase=FBgn0031021|UniProtKB=Q9VWI0 Q9VWI0 ND-18 PTHR12219:SF8 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;electron transport chain#GO:0022900;cellular respiration#GO:0045333;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 DROME|FlyBase=FBgn0050043|UniProtKB=Q8MKL0 Q8MKL0 CG30041_CG30043 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0034478|UniProtKB=Q4QPW2 Q4QPW2 Dmel\CG10822 PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0032187|UniProtKB=Q9VL34 Q9VL34 Dmel\CG4839 PTHR24353:SF144 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED cell surface receptor signaling pathway#GO:0007166;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;receptor guanylyl cyclase signaling pathway#GO:0007168;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0001330|UniProtKB=O46072 O46072 kz PTHR18934:SF99 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX37-RELATED helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0015622|UniProtKB=Q9VAL7 Q9VAL7 Cnx99A PTHR11073:SF1 CALRETICULIN AND CALNEXIN CALNEXIN 14D-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;catabolic process#GO:0009056;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 DROME|FlyBase=FBgn0032666|UniProtKB=Q0E8P5 Q0E8P5 Dmel\CG5758 PTHR10900:SF127 PERIOSTIN-RELATED FI05614P cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0035477|UniProtKB=Q9VZK7 Q9VZK7 Dmel\CG14982 PTHR14758:SF1 AGAP005440-PA CENTROSOME-ASSOCIATED FAM110 C-TERMINAL DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0030297|UniProtKB=Q9VYZ2 Q9VYZ2 Gr10b PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0050263|UniProtKB=Q9W2E1 Q9W2E1 stum PTHR21676:SF8 PROTEIN STUM PROTEIN STUM locomotion#GO:0040011;taxis#GO:0042330;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;response to external stimulus#GO:0009605;system process#GO:0003008;sensory perception#GO:0007600;neuromuscular process#GO:0050905;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877 dendritic tree#GO:0097447;neuron projection#GO:0043005;dendrite#GO:0030425;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0020617|UniProtKB=Q9W2Q1 Q9W2Q1 Rx PTHR24329:SF405 HOMEOBOX PROTEIN ARISTALESS RETINAL HOMEOBOX PROTEIN RX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0030164|UniProtKB=Q8IRM2 Q8IRM2 AAN09619 PTHR19143:SF470 FIBRINOGEN/TENASCIN/ANGIOPOEITIN GH05177P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0004110|UniProtKB=P22711 P22711 tin PTHR24340:SF41 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN CEH-24-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0037473|UniProtKB=Q9VI65 Q9VI65 Elmod PTHR12771:SF51 ENGULFMENT AND CELL MOTILITY LD01482P GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0052532|UniProtKB=Q9VWH1 Q9VWH1 CG14203 PTHR24329:SF520 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN UNC-42 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0063498|UniProtKB=Q7JYZ9 Q7JYZ9 GstE2 PTHR43969:SF4 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED FI01423P-RELATED catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 transferase#PC00220 DROME|FlyBase=FBgn0030403|UniProtKB=Q9VYL5 Q9VYL5 Dmel\CG1824 PTHR24221:SF674 ATP-BINDING CASSETTE SUB-FAMILY B MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0037492|UniProtKB=Q9VI85 Q9VI85 Dtwd2 PTHR21392:SF0 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 DROME|FlyBase=FBgn0035014|UniProtKB=Q9W161 Q9W161 Dmel\CG13581 PTHR35826:SF1 PROTEIN ATP6V1FNB-LIKE PROTEIN SPMIP1 ISOFORM X1 DROME|FlyBase=FBgn0031012|UniProtKB=Q9VWJ0 Q9VWJ0 Yqy PTHR11360:SF8 MONOCARBOXYLATE TRANSPORTER BCDNA.LD28120-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0031897|UniProtKB=M9PEZ6 M9PEZ6 BcDNA:SD10385 PTHR14856:SF9 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN SOLUTE CARRIER FAMILY 66 MEMBER 2 cytosolic transport#GO:0016482;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;localization#GO:0051179;lipid localization#GO:0010876;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;regulation of membrane lipid distribution#GO:0097035;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907 Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0000273|UniProtKB=P12370 P12370 Pka-C1 PTHR24353:SF153 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Endothelin signaling pathway#P00019>PKA#P00570;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Enkephalin release#P05913>PKA#P05972 DROME|FlyBase=FBgn0033963|UniProtKB=Q7JWV5 Q7JWV5 Dmel\CG12857 PTHR22667:SF0 AT01380P-RELATED AT01380P-RELATED DROME|FlyBase=FBgn0036821|UniProtKB=Q9VVT8 Q9VVT8 ACSL1 PTHR43272:SF116 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 1 ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 ligase#PC00142 DROME|FlyBase=FBgn0266465|UniProtKB=Q9VEN3 Q9VEN3 GckIII PTHR48012:SF10 STERILE20-LIKE KINASE, ISOFORM B-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003969|UniProtKB=Q8IR23 Q8IR23 vap PTHR10194:SF146 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Ras#P00886;EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646;Interleukin signaling pathway#P00036>RasGAP#P00975;Angiogenesis#P00005>GAP#P00205;Angiogenesis#P00005>RasGAP#P00190 DROME|FlyBase=FBgn0033733|UniProtKB=A1Z8Z9 A1Z8Z9 mdcds_23070 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;fatty acid metabolic process#GO:0006631;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436 ligase#PC00142 DROME|FlyBase=FBgn0024754|UniProtKB=O61491 O61491 Flo1 PTHR13806:SF47 FLOTILLIN-RELATED FLOTILLIN-1 positive regulation of cellular component organization#GO:0051130;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;positive regulation of endocytosis#GO:0045807;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 membrane microdomain#GO:0098857;cell periphery#GO:0071944;caveola#GO:0005901;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane raft#GO:0045121;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036680|UniProtKB=Q9VVC3 Q9VVC3 Cpr73D PTHR10380:SF246 CUTICLE PROTEIN CUTICULAR PROTEIN 73D, ISOFORM B extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0033379|UniProtKB=Q7KKH3 Q7KKH3 Mys45A PTHR12730:SF0 HSDA/SDA1-RELATED PROTEIN SDA1 HOMOLOG cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0022770|UniProtKB=O17452 O17452 PeriA PTHR23301:SF107 CHITIN BINDING PERITROPHIN-A LD20793P carbohydrate derivative binding#GO:0097367;binding#GO:0005488 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039240|UniProtKB=Q9VC19 Q9VC19 Dmel\CG3744 PTHR11731:SF193 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 9 peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 DROME|FlyBase=FBgn0034473|UniProtKB=Q9V8Y7 Q9V8Y7 Or56a PTHR21137:SF40 ODORANT RECEPTOR ODORANT RECEPTOR 56A molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0013679|UniProtKB=P18929 P18929 mt:ND1 PTHR11432:SF23 NADH DEHYDROGENASE SUBUNIT 1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0037556|UniProtKB=Q95T08 Q95T08 Dmel\CG9636 PTHR12493:SF0 CUE DOMAIN CONTAINING 2 CUE DOMAIN-CONTAINING PROTEIN 2 DROME|FlyBase=FBgn0034717|UniProtKB=Q7JWP9 Q7JWP9 tartan_capricious-like PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0033725|UniProtKB=Q7JR69 Q7JR69 Cpr49Ac PTHR10380:SF200 CUTICLE PROTEIN CUTICULAR PROTEIN 49AB-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0034165|UniProtKB=Q4V625 Q4V625 Dmel\CG6435 PTHR11195:SF13 DESTABILASE-RELATED LYSOZYME hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;lysozyme activity#GO:0003796;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0037883|UniProtKB=Q9VGQ9 Q9VGQ9 Dph3 PTHR21454:SF31 DPH3 HOMOLOG-RELATED DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3 transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872;iron ion binding#GO:0005506 primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0011704|UniProtKB=P48592 P48592 RnrS PTHR23409:SF18 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 oxidoreductase#PC00176;reductase#PC00198;metabolite interconversion enzyme#PC00262 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921 DROME|FlyBase=FBgn0025702|UniProtKB=M9MS50 M9MS50 Srpk79D PTHR47634:SF26 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SERINE-ARGININE PROTEIN KINASE AT 79D-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0035008|UniProtKB=Q0E8W8 Q0E8W8 CT11751 PTHR45752:SF196 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 4 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031232|UniProtKB=Q9VPL4 Q9VPL4 Dmel\CG11617 PTHR11211:SF3 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN MOHAWK RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;muscle organ development#GO:0007517;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0039192|UniProtKB=Q9VC84 Q9VC84 Dmel\CG17784 PTHR21398:SF11 AGAP007094-PA HDC15381-RELATED DROME|FlyBase=FBgn0263748|UniProtKB=M9PEP7 M9PEP7 CG8473 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0025720|UniProtKB=O96539 O96539 Ate1 PTHR21367:SF1 ARGININE-TRNA-PROTEIN TRANSFERASE 1 ARGINYL-TRNA--PROTEIN TRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;catalytic activity, acting on a tRNA#GO:0140101 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translational protein#PC00263 DROME|FlyBase=FBgn0034774|UniProtKB=Q9W200 Q9W200 Dmel\CG13526 PTHR23050:SF547 CALCIUM BINDING PROTEIN AT10229P-RELATED calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0053630|UniProtKB=Q4AB38 Q4AB38 CG12808 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0266579|UniProtKB=Q9VB15 Q9VB15 tau PTHR11501:SF19 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 developmental process#GO:0032502;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of microtubule-based process#GO:0032886;system development#GO:0048731;neuron development#GO:0048666;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;axon#GO:0030424;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0262009|UniProtKB=Q4V608 Q4V608 Dmel\CG42827 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0053511|UniProtKB=Q59DY3 Q59DY3 Dmel\CG33511 PTHR11012:SF48 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0037826|UniProtKB=Q9VGY1 Q9VGY1 Dmel\CG14689 PTHR21055:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 phosphatase modulator#PC00184 DROME|FlyBase=FBgn0032451|UniProtKB=M9PD12 M9PD12 spict PTHR12570:SF92 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED SPICHTHYIN, ISOFORM B metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transport#GO:0006810;magnesium ion transport#GO:0015693 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0026402|UniProtKB=Q9V7W9 Q9V7W9 NiPp1 PTHR23308:SF74 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE 1 enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;protein serine/threonine phosphatase inhibitor activity#GO:0004865;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;plasma membrane bounded cell projection organization#GO:0120036;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;regulation of BMP signaling pathway#GO:0030510;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;anatomical structure development#GO:0048856;system development#GO:0048731;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;positive regulation of BMP signaling pathway#GO:0030513;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;generation of neurons#GO:0048699 membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607 RNA splicing factor#PC00148 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 DROME|FlyBase=FBgn0032115|UniProtKB=Q9VLC4 Q9VLC4 Dmel\CG4438 PTHR22055:SF0 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0250816|UniProtKB=Q7PLK0 Q7PLK0 AGO3 PTHR22891:SF111 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676 regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 DROME|FlyBase=FBgn0027788|UniProtKB=Q7KM13 Q7KM13 Hey PTHR10985:SF138 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 DROME|FlyBase=FBgn0032805|UniProtKB=Q9VIU0 Q9VIU0 Dmel\CG10337 PTHR15422:SF45 OS05G0565100 PROTEIN ASCORBATE FERRIREDUCTASE (TRANSMEMBRANE) DROME|FlyBase=FBgn0013469|UniProtKB=M9PF84 M9PF84 klu PTHR24404:SF128 ZINC FINGER PROTEIN KLUMPFUSS, ISOFORM B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0031498|UniProtKB=Q9VQL2 Q9VQL2 Dmel\CG17260 PTHR40237:SF1 LD44813P LD44813P DROME|FlyBase=FBgn0030895|UniProtKB=Q9VWY5 Q9VWY5 Dmel\CG7135 PTHR11012:SF56 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0262588|UniProtKB=A0A0B4K7A7 A0A0B4K7A7 Dmel\CG43125 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0259737|UniProtKB=B7YZH2 B7YZH2 Dmel\CG42391 PTHR46427:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 STRUCTURE-SPECIFIC ENDONUCLEASE ANKLE1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;homologous recombination#GO:0035825;reproductive process#GO:0022414;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0036862|UniProtKB=Q9VVY3 Q9VVY3 Gbs-76A PTHR12307:SF61 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT GLYCOGEN-BINDING SUBUNIT 76A protein phosphatase binding#GO:0019903;carbohydrate binding#GO:0030246;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247 regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 DROME|FlyBase=FBgn0037576|UniProtKB=Q9VHS4 Q9VHS4 Or85a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034143|UniProtKB=A1ZAI3 A1ZAI3 CG8303 PTHR11011:SF130 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579 DROME|FlyBase=FBgn0029714|UniProtKB=Q9W4J5 Q9W4J5 CG3527 PTHR12636:SF5 NEP1/MRA1 RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;rRNA binding#GO:0019843;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA binding#GO:0003723;catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;transferase#PC00220 DROME|FlyBase=FBgn0051004|UniProtKB=Q0KHY3 Q0KHY3 mesh PTHR13802:SF52 MUCIN 4-RELATED NIDOGEN-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0004179|UniProtKB=Q03751 Q03751 Csp PTHR44027:SF8 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 axon#GO:0030424;axon terminus#GO:0043679;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;distal axon#GO:0150034;neuron projection terminus#GO:0044306;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0015754|UniProtKB=Q7KNS3 Q7KNS3 Lis-1 PTHR44129:SF18 WD REPEAT-CONTAINING PROTEIN POP1 LISSENCEPHALY-1 HOMOLOG cellular localization#GO:0051641;localization#GO:0051179;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;axonal transport#GO:0098930;centrosome localization#GO:0051642;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;intracellular transport#GO:0046907;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088 membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;kinetochore#GO:0000776 DROME|FlyBase=FBgn0030114|UniProtKB=Q7K0L2 Q7K0L2 Dmel\CG17754 PTHR24412:SF135 KELCH PROTEIN KELCH-LIKE PROTEIN 5 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0263198|UniProtKB=Q9VJ12 Q9VJ12 Acn PTHR46589:SF1 APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DROME|FlyBase=FBgn0039838|UniProtKB=Q9V9Y8 Q9V9Y8 CAH6 PTHR18952:SF137 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0035204|UniProtKB=Q961B3 Q961B3 Nt5a PTHR12103:SF38 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 DROME|FlyBase=FBgn0031782|UniProtKB=Q6NL34 Q6NL34 WDR79 PTHR13211:SF1 TELOMERASE CAJAL BODY PROTEIN 1 TELOMERASE CAJAL BODY PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0038956|UniProtKB=Q4V4S9 Q4V4S9 CAH8 PTHR18952:SF137 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0010109|UniProtKB=Q26263 Q26263 dpn PTHR10985:SF156 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED PROTEIN DEADPAN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0029689|UniProtKB=Q9W4N6 Q9W4N6 CG-6428 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040 DROME|FlyBase=FBgn0266580|UniProtKB=A1Z6H7 A1Z6H7 Gp210 PTHR23019:SF3 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210 intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 DROME|FlyBase=FBgn0042111|UniProtKB=Q9I7H8 Q9I7H8 CG5995 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 DROME|FlyBase=FBgn0041004|UniProtKB=Q8SYF7 Q8SYF7 Dmel\CG17715 PTHR21706:SF15 TRANSMEMBRANE PROTEIN 65 LP09246P intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0036565|UniProtKB=Q9VUY0 Q9VUY0 CG5235 PTHR10157:SF43 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576 hydroxylase#PC00122 DROME|FlyBase=FBgn0031418|UniProtKB=Q9VQB4 Q9VQB4 Dmel\CG3609 PTHR22604:SF105 OXIDOREDUCTASES TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0053099|UniProtKB=Q86B83 Q86B83 CG5340 PTHR10209:SF885 OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN FI07970P-RELATED oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0016081|UniProtKB=Q9VT28 Q9VT28 fry PTHR12295:SF35 FURRY-RELATED PROTEIN FURRY multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699 cell division site#GO:0032153;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030815|UniProtKB=Q9VX86 Q9VX86 Cg8945 PTHR11705:SF89 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0038271|UniProtKB=Q9VFF0 Q9VFF0 UQCR-C1 PTHR11851:SF149 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT BETA catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;endopeptidase complex#GO:1905369;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0016032|UniProtKB=Q24188 Q24188 lbm PTHR19282:SF521 TETRASPANIN AT12771P-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038832|UniProtKB=Q8SY05 Q8SY05 gi7300665 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0030805|UniProtKB=Q9VX95 Q9VX95 wus PTHR44733:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 DROME|FlyBase=FBgn0051481|UniProtKB=P31264 P31264 pb PTHR45664:SF2 PROTEIN ZERKNUELLT 1-RELATED HOMEOTIC PROTEIN PROBOSCIPEDIA-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0265045|UniProtKB=A0A0B4KG35 A0A0B4KG35 Strn-Mlck PTHR13817:SF151 TITIN BENT, ISOFORM F-RELATED structural molecule activity#GO:0005198 cell development#GO:0048468;actomyosin structure organization#GO:0031032;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989 contractile muscle fiber#GO:0043292;A band#GO:0031672;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;M band#GO:0031430;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016 structural protein#PC00211 DROME|FlyBase=FBgn0032262|UniProtKB=Q9VKU2 Q9VKU2 Dmel\CG7384 PTHR20992:SF9 AT15442P-RELATED AT15442P-RELATED DROME|FlyBase=FBgn0037809|UniProtKB=Q9VH00 Q9VH00 Dmel\CG12818 PTHR22093:SF0 LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1 LEUKOCYTE RECEPTOR CLUSTER MEMBER 1 DROME|FlyBase=FBgn0036363|UniProtKB=Q9VU74 Q9VU74 Dmel\CG10140 PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;carbohydrate derivative binding#GO:0097367 external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0040508|UniProtKB=Q9VK53 Q9VK53 ACXC PTHR45627:SF12 ADENYLATE CYCLASE TYPE 1 ADENYLYL CYCLASE X E-RELATED adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0051528|UniProtKB=Q8IPM2 Q8IPM2 Dmel\CG31528 PTHR10677:SF3 UBIQUILIN FI07626P-RELATED binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;protein binding#GO:0005515 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0040505|UniProtKB=Q7KJ08 Q7KJ08 Alk PTHR24416:SF604 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of developmental process#GO:0050793;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of neuron differentiation#GO:0045664;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell differentiation#GO:0045595;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0034956|UniProtKB=Q8SYM5 Q8SYM5 Dmel\CG4324 PTHR24064:SF445 SOLUTE CARRIER FAMILY 22 MEMBER AT15560P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0053721|UniProtKB=Q0KI29 Q0KI29 CR33721 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0026315|UniProtKB=Q9VGS9 Q9VGS9 Ugt35A1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740 DROME|FlyBase=FBgn0033844|UniProtKB=A0A0B4K7Y4 A0A0B4K7Y4 bbc PTHR10414:SF78 ETHANOLAMINEPHOSPHOTRANSFERASE DIACYLGLYCEROL CHOLINEPHOSPHOTRANSFERASE transferase#PC00220 DROME|FlyBase=FBgn0038295|UniProtKB=Q8INF0 Q8INF0 Gyc88E PTHR45655:SF20 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 SOLUBLE GUANYLATE CYCLASE 88E binding#GO:0005488;small molecule binding#GO:0036094;lyase activity#GO:0016829;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;guanylate cyclase activity#GO:0004383 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cytosol#GO:0005829 guanylate cyclase#PC00114;cyclase#PC00079 DROME|FlyBase=FBgn0030493|UniProtKB=Q9VYC2 Q9VYC2 Dmel\CG15756 PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0265137|UniProtKB=Q7K8Y5 Q7K8Y5 Spn42Da PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0260779|UniProtKB=Q9VE09 Q9VE09 GatA PTHR11895:SF179 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a tRNA#GO:0140101 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0035496|UniProtKB=Q9VZI5 Q9VZI5 SPH97 PTHR24256:SF462 TRYPTASE-RELATED LP21446P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0036984|UniProtKB=Q9VPG2 Q9VPG2 dCat-4 PTHR43243:SF108 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0030174|UniProtKB=M9NDT2 M9NDT2 CT35293 PTHR12231:SF278 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN KAPPA, ISOFORM A protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular process#GO:0009987 neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell junction#GO:0030054;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0031049|UniProtKB=Q9VWE9 Q9VWE9 Sec61gamma PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization within membrane#GO:0051668;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 primary active transporter#PC00068 DROME|FlyBase=FBgn0039229|UniProtKB=Q8IMV6 Q8IMV6 Saf-B PTHR15683:SF8 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B, ISOFORM B nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0031708|UniProtKB=Q9VMR0 Q9VMR0 Dmel\CG7382 PTHR13032:SF6 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542 mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0004580|UniProtKB=P41044 P41044 Cbp53E PTHR19972:SF16 CALBINDIN CALBINDIN-32 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axon#GO:0030424;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425;distal axon#GO:0150034;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;axon terminus#GO:0043679;cell junction#GO:0030054;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;nucleus#GO:0005634;neuron projection#GO:0043005;presynapse#GO:0098793;cytosol#GO:0005829 calmodulin-related#PC00061 DROME|FlyBase=FBgn0034423|UniProtKB=Q4V5A7 Q4V5A7 tbrd-2 PTHR22880:SF225 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS HOMEOTIC PROTEIN FEMALE STERILE-RELATED chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0037703|UniProtKB=Q9VHC5 Q9VHC5 Kdm3 PTHR12549:SF11 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3 DNA binding#GO:0003677;histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;chromatin DNA binding#GO:0031490;histone demethylase activity#GO:0032452 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0266709|UniProtKB=Q9VU41 Q9VU41 Zmynd10 PTHR13244:SF7 ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10 inner dynein arm assembly#GO:0036159;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039347|UniProtKB=Q8IMS5 Q8IMS5 BcDNA:AT31683 PTHR11071:SF597 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SUBFAMILY NOT NAMED nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 DROME|FlyBase=FBgn0036995|UniProtKB=Q9VPF0 Q9VPF0 atk PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0020521|UniProtKB=Q8IRK0 Q8IRK0 pio PTHR22907:SF54 GH04558P GH04558P DROME|FlyBase=FBgn0030701|UniProtKB=A0A4D6K4K0 A0A4D6K4K0 Dmel\CG16952 PTHR16064:SF3 BTB POZ DOMAIN CONTAINING 7 BTB_POZ DOMAIN-CONTAINING PROTEIN 7 DROME|FlyBase=FBgn0028963|UniProtKB=Q9V6H2 Q9V6H2 Or49b PTHR21137:SF3 ODORANT RECEPTOR ODORANT RECEPTOR 30A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0041231|UniProtKB=Q9VTN0 Q9VTN0 Gr68a PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0036485|UniProtKB=Q9VUL9 Q9VUL9 FucTA PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE GLYCOPROTEIN 3-ALPHA-L-FUCOSYLTRANSFERASE A fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0264339|UniProtKB=A8DY43 A8DY43 Dmel\CG43795 PTHR32546:SF29 G-PROTEIN COUPLED RECEPTOR 158-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0086129|UniProtKB=Q9XZ21 Q9XZ21 snama PTHR15439:SF0 RETINOBLASTOMA-BINDING PROTEIN 6 E3 UBIQUITIN-PROTEIN LIGASE RBBP6 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0015338|UniProtKB=Q9V3I6 Q9V3I6 anon-35Fc PTHR12869:SF0 SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN BOS COMPLEX SUBUNIT TMEM147 DROME|FlyBase=FBgn0010638|UniProtKB=Q7JZN0 Q7JZN0 Sec61beta PTHR13509:SF26 SEC61 SUBUNIT BETA PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 localization within membrane#GO:0051668;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;rough endoplasmic reticulum#GO:0005791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0039378|UniProtKB=Q9VBL5 Q9VBL5 alpha4GT2 PTHR12042:SF31 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE 1-RELATED UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032444|UniProtKB=Q9VK69 Q9VK69 CCT4 PTHR11353:SF26 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT DELTA metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829;chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 DROME|FlyBase=FBgn0036510|UniProtKB=Q9VUQ8 Q9VUQ8 SCCRO PTHR12281:SF32 RP42 RELATED DCN1-LIKE PROTEIN 1 binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0260008|UniProtKB=A8Y535 A8Y535 UQCR-11 PTHR15336:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069 reductase#PC00198;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0051424|UniProtKB=Q8IN09 Q8IN09 Ir94b PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0039844|UniProtKB=A0A0B4KHK8 A0A0B4KHK8 Dmel\CG1607 PTHR11785:SF531 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1 amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0039554|UniProtKB=Q9VAZ0 Q9VAZ0 FBXL8 PTHR12904:SF32 FAMILY NOT NAMED FI05230P DROME|FlyBase=FBgn0031061|UniProtKB=Q9VWD5 Q9VWD5 Acbp8 PTHR22973:SF12 LD35087P LD35087P DROME|FlyBase=FBgn0036500|UniProtKB=Q9VUN7 Q9VUN7 Dmel\CG7275 PTHR22851:SF0 U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 13 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0284252|UniProtKB=P91927 P91927 Letm1 PTHR14009:SF40 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;organelle organization#GO:0006996;monoatomic ion transmembrane transport#GO:0034220;mitochondrion organization#GO:0007005;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular component organization#GO:0016043;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0259146|UniProtKB=Q9VBJ3 Q9VBJ3 fid PTHR13069:SF37 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 FIRE DANCER catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175;nucleic acid binding#GO:0003676;binding#GO:0005488;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0032752|UniProtKB=Q9VJ04 Q9VJ04 Dmel\CG10702 PTHR21662:SF59 RECEPTOR PROTEIN-TYROSINE KINASE RECEPTOR PROTEIN-TYROSINE KINASE DROME|FlyBase=FBgn0038642|UniProtKB=Q9VE45 Q9VE45 Muc91C PTHR15363:SF4 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 CUTICLE PROTEIN 16.5-RELATED transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032629|UniProtKB=Q8SY13 Q8SY13 beat-IIIc PTHR21261:SF19 BEAT PROTEIN BEATEN PATH IIIA, ISOFORM D-RELATED cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;anatomical structure morphogenesis#GO:0009653 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0051388|UniProtKB=Q9VGQ5 Q9VGQ5 CG5135 PTHR24390:SF289 ZINC FINGER PROTEIN GH10523P DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0017418|UniProtKB=Q94981 Q94981 ari-1 PTHR11685:SF475 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0037467|UniProtKB=Q9VI55 Q9VI55 Ufl1 PTHR31057:SF0 E3 UFM1-PROTEIN LIGASE 1 E3 UFM1-PROTEIN LIGASE 1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 response to stress#GO:0006950;reticulophagy#GO:0061709;autophagy#GO:0006914;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;catabolic process#GO:0009056;macroautophagy#GO:0016236;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0036348|UniProtKB=Q9VU57 Q9VU57 Dmel\CG17687 PTHR14885:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43 cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226 DROME|FlyBase=FBgn0032916|UniProtKB=Q9VIG0 Q9VIG0 Dmel\CG9257 PTHR13460:SF0 FAMILY NOT NAMED MALECTIN carbohydrate binding#GO:0030246;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0086757|UniProtKB=Q7K4K7 Q7K4K7 Golgin97 PTHR23157:SF24 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GOLGIN SUBFAMILY A MEMBER 1 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 DROME|FlyBase=FBgn0039852|UniProtKB=Q9V9X0 Q9V9X0 nyo PTHR47327:SF1 FI18240P1-RELATED FI18240P1-RELATED anatomical structure development#GO:0048856;developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653 DROME|FlyBase=FBgn0015737|UniProtKB=Q9VB46 Q9VB46 Hmu PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 DROME|FlyBase=FBgn0030530|UniProtKB=Q9VY77 Q9VY77 jub PTHR24219:SF4 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN JUB transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of response to stimulus#GO:0048583;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;regulation of signaling#GO:0023051;negative regulation of translation#GO:0017148;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of hippo signaling#GO:0035330;negative regulation of metabolic process#GO:0009892 adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;cell-cell junction#GO:0005911;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0032138|UniProtKB=Q9VL96 Q9VL96 CG4364 PTHR12221:SF6 PESCADILLO - RELATED PESCADILLO HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037592|UniProtKB=Q9VHQ5 Q9VHQ5 Dmel\CG11737 PTHR12459:SF27 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 DROME|FlyBase=FBgn0261574|UniProtKB=Q9VW71 Q9VW71 kug PTHR24026:SF125 FAT ATYPICAL CADHERIN-RELATED FAT-LIKE CADHERIN-RELATED TUMOR SUPPRESSOR HOMOLOG cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 DROME|FlyBase=FBgn0004513|UniProtKB=Q00748 Q00748 Mdr65 PTHR24221:SF503 ATP-BINDING CASSETTE SUB-FAMILY B MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49-RELATED transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0045770|UniProtKB=Q961W5 Q961W5 S-Lap3 PTHR11963:SF16 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0031529|UniProtKB=Q9VQP9 Q9VQP9 Ostc PTHR13160:SF4 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0262872|UniProtKB=Q960V3 Q960V3 milt PTHR15751:SF12 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN MILT binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;protein targeting#GO:0006605;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;mitochondrion localization#GO:0051646;vesicle cytoskeletal trafficking#GO:0099518;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle localization#GO:0051648 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;vesicle#GO:0031982 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0038268|UniProtKB=Q95T10 Q95T10 CG3631 PTHR12450:SF14 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 GLYCOSAMINOGLYCAN XYLOSYLKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0002909|UniProtKB=Q9VS48 Q9VS48 mus312 PTHR21541:SF3 BTB POZ DOMAIN CONTAINING 12 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4 cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;meiosis I#GO:0007127;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049;reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0000618|UniProtKB=Q9VYX1 Q9VYX1 e(y)2 PTHR12514:SF1 ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;metabolic process#GO:0008152;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nuclear transport#GO:0051169;nuclear export#GO:0051168;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of DNA-templated transcription#GO:0006355;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;RNA localization#GO:0006403;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;chromatin#GO:0000785;SAGA complex#GO:0000124;DUBm complex#GO:0071819;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0283494|UniProtKB=Q9U915 Q9U915 Ak2 PTHR23359:SF234 NUCLEOTIDE KINASE ADENYLATE KINASE 2, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;phosphotransferase activity, phosphate group as acceptor#GO:0016776 nucleoside phosphate biosynthetic process#GO:1901293;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;nucleoside diphosphate metabolic process#GO:0009132;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 DROME|FlyBase=FBgn0033378|UniProtKB=Q9V535 Q9V535 tsu PTHR45894:SF1 RNA-BINDING PROTEIN 8A RNA-BINDING PROTEIN 8A RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0036278|UniProtKB=M9PF00 M9PF00 CrzR PTHR24230:SF164 G-PROTEIN COUPLED RECEPTOR CORAZONIN RECEPTOR, ISOFORM B neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0260005|UniProtKB=Q9VHY7 Q9VHY7 wtrw PTHR24197:SF44 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54-RELATED DROME|FlyBase=FBgn0020616|UniProtKB=Q9VM62 Q9VM62 SA1 PTHR11199:SF0 STROMAL ANTIGEN LD34181P-RELATED chromatin binding#GO:0003682;binding#GO:0005488 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;cell cycle process#GO:0022402;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0039800|UniProtKB=Q9VA42 Q9VA42 Npc2g PTHR11306:SF55 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED GEO08227P1-RELATED steroid binding#GO:0005496;lipid binding#GO:0008289;binding#GO:0005488;sterol binding#GO:0032934 lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;sterol transport#GO:0015918;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;lipid transport#GO:0006869 DROME|Gene_ORFName=Dmel_CG3830|UniProtKB=A0ACD4DAQ9 A0ACD4DAQ9 vg PTHR15950:SF15 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN PROTEIN VESTIGIAL-RELATED regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0037114|UniProtKB=Q9VP00 Q9VP00 Cpr78E PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0034221|UniProtKB=A1ZAT2 A1ZAT2 Dmel\CG10764 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0259195|UniProtKB=Q9VXT4 Q9VXT4 CG15644 PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;recombinational repair#GO:0000725;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;protein sumoylation#GO:0016925;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 condensed chromosome#GO:0000793;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0285947|UniProtKB=Q9VWG3 Q9VWG3 RpS10b PTHR12146:SF0 40S RIBOSOMAL PROTEIN S10 RIBOSOMAL PROTEIN S10 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 DROME|FlyBase=FBgn0038428|UniProtKB=Q9VEV3 Q9VEV3 Ttc1 PTHR46014:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 DROME|FlyBase=FBgn0085371|UniProtKB=A8JNC9 A8JNC9 CG32422 PTHR11011:SF81 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0039335|UniProtKB=Q9VBR1 Q9VBR1 Vps33B PTHR11679:SF92 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33B intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 lytic vacuole#GO:0000323;vesicle tethering complex#GO:0099023;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0032470|UniProtKB=Q9VK41 Q9VK41 Ttc30 PTHR20931:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 30 TETRATRICOPEPTIDE REPEAT PROTEIN 30 protein-containing complex binding#GO:0044877;binding#GO:0005488 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856 DROME|FlyBase=FBgn0264895|UniProtKB=A8DYW8 A8DYW8 RapGAP1 PTHR15711:SF22 RAP GTPASE-ACTIVATING PROTEIN RAP GTPASE ACTIVATING PROTEIN 1, ISOFORM H enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0003044|UniProtKB=Q24459 Q24459 Pcl PTHR13037:SF24 FORMIN POLYCOMB PROTEIN PCL-RELATED DROME|FlyBase=FBgn0039897|UniProtKB=H9XVM9 H9XVM9 Dmel\CG1674 PTHR24217:SF0 PUTATIVE-RELATED SYNAPTOPODIN 2-LIKE PROTEIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of actin filament organization#GO:0110053;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;regulation of response to stimulus#GO:0048583;regulation of actin filament-based process#GO:0032970;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of actin filament bundle assembly#GO:0032233;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of organelle organization#GO:0010638 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0260453|UniProtKB=Q9VKP4 Q9VKP4 CG31722-B PTHR11743:SF70 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL GH26960P-RELATED monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234 membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0040087|UniProtKB=Q9W3N6 Q9W3N6 p115 PTHR10013:SF7 GENERAL VESICULAR TRANSPORT FACTOR P115 GENERAL VESICULAR TRANSPORT FACTOR P115 intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;membrane fusion#GO:0061025;cellular component organization#GO:0016043;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;membrane organization#GO:0061024 coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi stack#GO:0005795;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0032205|UniProtKB=Q9VL11 Q9VL11 Dmel\CG4957 PTHR12532:SF12 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031628|UniProtKB=Q9VR26 Q9VR26 Dmel\CG3294 PTHR12620:SF4 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT ZINC FINGER (CCCH TYPE), RNA-BINDING MOTIF AND SERINE_ARGININE RICH 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0003612|UniProtKB=A1Z7P5 A1Z7P5 Su(var)2-10 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;protein sumoylation#GO:0016925;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 DROME|FlyBase=FBgn0029958|UniProtKB=Q9W3Q1 Q9W3Q1 Pdp PTHR13832:SF792 PROTEIN PHOSPHATASE 2C GM14286P catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 DPP signaling pathway#P06213>PDP#P06280;BMP/activin signaling pathway-drosophila#P06211>PDP#P06248;SCW signaling pathway#P06216>PDP#P06324;GBB signaling pathway#P06214>PDP#P06297;DPP-SCW signaling pathway#P06212>PDP#P06262 DROME|FlyBase=FBgn0020638|UniProtKB=C0HL64 C0HL64 Lcp65Ag1 PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0031117|UniProtKB=E1JJS1 E1JJS1 GstT3 PTHR43917:SF8 FAMILY NOT NAMED GH16740P-RELATED glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 DROME|FlyBase=FBgn0031247|UniProtKB=Q9VPN3 Q9VPN3 Dmel\CG11562 PTHR28163:SF1 PROTEIN PET117 HOMOLOG, MITOCHONDRIAL PROTEIN PET117 HOMOLOG, MITOCHONDRIAL cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0053514|UniProtKB=Q6NLM7 Q6NLM7 CG15018 PTHR10174:SF216 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN-RELATED ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0003053|UniProtKB=Q9W4J1 Q9W4J1 peb PTHR46451:SF1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0266410|UniProtKB=Q9VHF4 Q9VHF4 drn PTHR10634:SF149 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0037603|UniProtKB=Q9VHP1 Q9VHP1 Sys1 PTHR12952:SF0 SYS1 PROTEIN SYS1 HOMOLOG Golgi to endosome transport#GO:0006895;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;Golgi to plasma membrane protein transport#GO:0043001;cytosolic transport#GO:0016482;protein localization to organelle#GO:0033365;Golgi to plasma membrane transport#GO:0006893;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;protein localization to Golgi apparatus#GO:0034067;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0262683|UniProtKB=M9NEZ8 M9NEZ8 lincRNA.110 PTHR38572:SF1 BCDNA.GH07269-RELATED BCDNA.GH07269-RELATED DROME|FlyBase=FBgn0053147|UniProtKB=Q8MRE7 Q8MRE7 Hs3st-A PTHR10605:SF65 HEPARAN SULFATE SULFOTRANSFERASE GH20068P transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0261386|UniProtKB=A0A6I8WFJ4 A0A6I8WFJ4 Gpa2 PTHR31129:SF2 GLYCOPROTEIN HORMONE ALPHA-2 GLYCOPROTEIN HORMONES ALPHA CHAIN protein binding#GO:0005515;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 DROME|FlyBase=FBgn0260934|UniProtKB=A1ZBL9 A1ZBL9 par-1 PTHR24346:SF114 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 3-RELATED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036969|UniProtKB=Q9VWB4 Q9VWB4 Spn77Bb PTHR11461:SF367 SERINE PROTEASE INHIBITOR, SERPIN GH21475P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0029118|UniProtKB=Q9V470 Q9V470 ScsbetaG PTHR11815:SF18 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ligase#PC00142 DROME|FlyBase=FBgn0065032|UniProtKB=Q9VX82 Q9VX82 Arpc3B PTHR12391:SF0 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Integrin signalling pathway#P00034>Arp2/3#P00912;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 DROME|FlyBase=FBgn0036142|UniProtKB=Q9VTG5 Q9VTG5 Adck5 PTHR43173:SF28 ABC1 FAMILY PROTEIN AARF DOMAIN CONTAINING KINASE 5 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0264005|UniProtKB=Q9VEI9 Q9VEI9 Hmx PTHR46110:SF3 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0033728|UniProtKB=Q95RB2 Q95RB2 Cpr49Ae PTHR10380:SF217 CUTICLE PROTEIN CUTICULAR PROTEIN 49AE extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0034644|UniProtKB=Q9W2E9 Q9W2E9 Ip6k PTHR12400:SF21 INOSITOL POLYPHOSPHATE KINASE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;organophosphate biosynthetic process#GO:0090407 kinase#PC00137 DROME|FlyBase=FBgn0259214|UniProtKB=Q59DP9 Q59DP9 PMCA PTHR24093:SF535 CATION TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 primary active transporter#PC00068 DROME|FlyBase=FBgn0036928|UniProtKB=Q95RF6 Q95RF6 Tom20 PTHR12430:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20 mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;nucleobase-containing compound transport#GO:0015931;mitochondrial transport#GO:0006839;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0001087|UniProtKB=P54362 P54362 g PTHR22781:SF14 DELTA ADAPTIN-RELATED AP-3 COMPLEX SUBUNIT DELTA-1 anterograde synaptic vesicle transport#GO:0048490;vesicle cytoskeletal trafficking#GO:0099518;intracellular protein localization#GO:0008104;vesicle budding from membrane#GO:0006900;establishment of protein localization to organelle#GO:0072594;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;membrane organization#GO:0061024;synaptic vesicle recycling#GO:0036465;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;synaptic vesicle membrane organization#GO:0048499;axo-dendritic transport#GO:0008088;anterograde axonal transport#GO:0008089;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;endosome to lysosome transport#GO:0008333;axonal transport#GO:0098930;protein localization to vacuole#GO:0072665;organelle localization#GO:0051640;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;endosomal transport#GO:0016197;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;establishment of vesicle localization#GO:0051650;endomembrane system organization#GO:0010256;organelle transport along microtubule#GO:0072384;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;protein targeting to vacuole#GO:0006623;synaptic vesicle transport#GO:0048489;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;establishment of organelle localization#GO:0051656;protein localization to lysosome#GO:0061462;cellular component organization#GO:0016043 vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;organelle membrane#GO:0031090;axon terminus#GO:0043679;membrane protein complex#GO:0098796;vesicle#GO:0031982;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;intracellular membrane-bounded organelle#GO:0043231;axon#GO:0030424;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;presynapse#GO:0098793;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;cell junction#GO:0030054;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;coated membrane#GO:0048475 transporter#PC00227 DROME|FlyBase=FBgn0264503|UniProtKB=Q9W2X8 Q9W2X8 CG12644 PTHR22747:SF18 NUCLEOPLASMIN GEO09167P1-RELATED chaperone#PC00072 DROME|FlyBase=FBgn0038170|UniProtKB=Q9VFS4 Q9VFS4 Dmel\CG14367 PTHR21532:SF0 PHOSPHODIESTERASE HL CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;ciliary base#GO:0097546 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 DROME|FlyBase=FBgn0034730|UniProtKB=Q9W250 Q9W250 ppk12 PTHR11690:SF243 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 12-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0263316|UniProtKB=Q9VGM1 Q9VGM1 Mrp4 PTHR24223:SF448 ATP-BINDING CASSETTE SUB-FAMILY C FI20146P1-RELATED transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0029504|UniProtKB=Q9W3Q5 Q9W3Q5 CHES-1-like PTHR45881:SF7 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED DROME|FlyBase=FBgn0033323|UniProtKB=Q8SZV0 Q8SZV0 anon-WO0140519.77 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;monoatomic ion homeostasis#GO:0050801;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0030346|UniProtKB=Q9VYT1 Q9VYT1 BORCS5 PTHR31634:SF2 BLOC-1-RELATED COMPLEX SUBUNIT 5 BLOC-1-RELATED COMPLEX SUBUNIT 5 organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;regulation of microtubule-based movement#GO:0060632;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;regulation of localization#GO:0032879;regulation of transport#GO:0051049;lysosome localization#GO:0032418;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;biological regulation#GO:0065007 intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;cell junction#GO:0030054;cytoplasmic side of membrane#GO:0098562;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;lysosomal membrane#GO:0005765;presynapse#GO:0098793;secretory vesicle#GO:0099503;side of membrane#GO:0098552;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708 DROME|FlyBase=FBgn0033614|UniProtKB=A1Z8I9 A1Z8I9 Obp47b PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0261822|UniProtKB=Q7KTJ7 Q7KTJ7 Bsg PTHR10075:SF104 BASIGIN RELATED BASIGIN, ISOFORM G cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0031815|UniProtKB=Q9VMD5 Q9VMD5 frj PTHR13906:SF16 PORCUPINE MEMBRANE-BOUND ACYLGLYCEROPHOSPHATIDYLINOSITOL O-ACYLTRANSFERASE MBOAT7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;lipid modification#GO:0030258;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644 membrane#GO:0016020;organelle membrane contact site#GO:0044232;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;organelle#GO:0043226;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 DROME|FlyBase=FBgn0037073|UniProtKB=Q9VP47 Q9VP47 Tsr1 PTHR12858:SF1 RIBOSOME BIOGENESIS PROTEIN PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;RNA binding#GO:0003723;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684 DROME|FlyBase=FBgn0003495|UniProtKB=P48607 P48607 spz PTHR23199:SF18 NEUROTROPHIN 1-RELATED PROTEIN SPAETZLE-RELATED signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;response to external stimulus#GO:0009605;innate immune response#GO:0045087;multicellular organism development#GO:0007275;developmental process#GO:0032502;response to other organism#GO:0051707;nervous system development#GO:0007399;defense response to other organism#GO:0098542;multicellular organismal process#GO:0032501;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Toll pathway-drosophila#P06217>SPZ#P06349;Toll pathway-drosophila#P06217>SPZ full length#P06347 DROME|FlyBase=FBgn0039348|UniProtKB=Q9VBP9 Q9VBP9 Npl4 PTHR12710:SF0 NUCLEAR PROTEIN LOCALIZATION 4 NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 DROME|FlyBase=FBgn0053654|UniProtKB=Q4AB39 Q4AB39 Dmel\CG33654 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0036229|UniProtKB=Q9VTR4 Q9VTR4 Dmel\CG7248 PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;carbohydrate derivative binding#GO:0097367 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 DROME|FlyBase=FBgn0053798|UniProtKB=A1Z977 A1Z977 Dmel\CG33798 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0027537|UniProtKB=Q9XZ06 Q9XZ06 Nup93-1 PTHR11225:SF4 NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP93 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406 nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 transporter#PC00227 DROME|FlyBase=FBgn0085284|UniProtKB=A8JNV4 A8JNV4 Blos3 PTHR31974:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 3 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 3 microtubule-based transport#GO:0099111;cellular localization#GO:0051641;cell differentiation#GO:0030154;response to stimulus#GO:0050896;establishment of organelle localization#GO:0051656;microtubule-based process#GO:0007017;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;developmental pigmentation#GO:0048066;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;cellular pigmentation#GO:0033059;axonal transport#GO:0098930;organelle localization#GO:0051640;pigmentation#GO:0043473;localization#GO:0051179;anterograde axonal transport#GO:0008089;cellular response to stimulus#GO:0051716;microtubule-based movement#GO:0007018;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;developmental process#GO:0032502;transport#GO:0006810;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;anterograde synaptic vesicle transport#GO:0048490;response to external stimulus#GO:0009605;vesicle cytoskeletal trafficking#GO:0099518;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;developmental maturation#GO:0021700;cytoskeleton-dependent intracellular transport#GO:0030705 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083 DROME|FlyBase=FBgn0014184|UniProtKB=P54361 P54361 Oda PTHR10279:SF10 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0030196|UniProtKB=Q9W2V7 Q9W2V7 Psf3 PTHR22768:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;GINS complex#GO:0000811;organelle lumen#GO:0043233;chromosome#GO:0005694;DNA replication preinitiation complex#GO:0031261;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0051017|UniProtKB=Q961I8 Q961I8 PH4alphaNE3 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;oxidoreductase complex#GO:1990204;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0085353|UniProtKB=Q9VYC9 Q9VYC9 CG12726 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0290397|UniProtKB=Q9VCC9 Q9VCC9 Tsc1 PTHR15154:SF2 HAMARTIN HAMARTIN regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of TOR signaling#GO:0032006;negative regulation of cell population proliferation#GO:0008285;negative regulation of cell communication#GO:0010648;regulation of cell population proliferation#GO:0042127;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC1#P04495;p53 pathway by glucose deprivation#P04397>TSC1#P04645 DROME|FlyBase=FBgn0030071|UniProtKB=Q9W3A7 Q9W3A7 Dmel\CG12661 PTHR21096:SF0 PROTEIN FAM136A TIM DOUBLE TWIN CX3C MOTIF PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0261808|UniProtKB=A8JQX3 A8JQX3 cu PTHR12121:SF45 CARBON CATABOLITE REPRESSOR PROTEIN 4 NOCTURNIN hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of RNA metabolic process#GO:0051254;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0033667|UniProtKB=A1Z8Q9 A1Z8Q9 reb PTHR22742:SF2 EXPANSION, ISOFORM A-RELATED EXPANSION, ISOFORM A-RELATED DROME|FlyBase=FBgn0030572|UniProtKB=Q9VY28 Q9VY28 mRpS25 PTHR13274:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN MS25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 DROME|FlyBase=FBgn0033566|UniProtKB=A1Z8D5 A1Z8D5 Dmel\CG18004 PTHR21812:SF1 INO80 COMPLEX SUBUNIT E INO80 COMPLEX SUBUNIT E cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of DNA replication#GO:0006275;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;positive regulation of RNA metabolic process#GO:0051254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 DROME|FlyBase=FBgn0030864|UniProtKB=Q9VX24 Q9VX24 Dmel\CG8173 PTHR43289:SF14 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0037067|UniProtKB=Q9VP56 Q9VP56 Cpr78Ca PTHR10380:SF238 CUTICLE PROTEIN CUTICULAR PROTEIN 65EA-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0287725|UniProtKB=Q9W3W6 Q9W3W6 sov PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0015075|UniProtKB=Q9VNV3 Q9VNV3 Ddx1 PTHR24031:SF307 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX1 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0036942|UniProtKB=Q9VW84 Q9VW84 Khk PTHR43085:SF55 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;carbohydrate metabolic process#GO:0005975;regulation of carbohydrate biosynthetic process#GO:0043255;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;transferase#PC00220 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 DROME|FlyBase=FBgn0004581|UniProtKB=Q9W1I2 Q9W1I2 bgcn PTHR18934:SF229 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX30 RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0033554|UniProtKB=A1Z8C4 A1Z8C4 Lsm10 PTHR21196:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770 DROME|FlyBase=FBgn0004892|UniProtKB=Q9VQS7 Q9VQS7 sob PTHR14196:SF11 ODD-SKIPPED - RELATED PROTEIN SISTER OF ODD AND BOWEL sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;tube morphogenesis#GO:0035239;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;tube development#GO:0035295;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;embryo development#GO:0009790;negative regulation of macromolecule biosynthetic process#GO:0010558;embryonic pattern specification#GO:0009880 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0039462|UniProtKB=Q9VBA2 Q9VBA2 Dmel\CG14252 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0262699|UniProtKB=Q9W4H9 Q9W4H9 fzr PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;binding#GO:0005488 positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0051821|UniProtKB=Q9VJN0 Q9VJN0 CG7647 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 serine protease#PC00203 DROME|FlyBase=FBgn0038373|UniProtKB=Q9VF23 Q9VF23 Argk3 PTHR11547:SF38 ARGININE OR CREATINE KINASE ARGININE KINASE 1-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0004880|UniProtKB=Q9VZK2 Q9VZK2 scrt PTHR23226:SF139 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER X-CHROMOSOMAL PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0004370|UniProtKB=P35992 P35992 Ptp10D PTHR19134:SF553 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;axon guidance#GO:0007411;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Axon guidance mediated by Slit/Robo#P00008>Ptp10D#P00343 DROME|FlyBase=FBgn0044817|UniProtKB=Q9NIV2 Q9NIV2 Ste12DOR PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;serine/threonine protein kinase complex#GO:1902554 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0050371|UniProtKB=A1Z7D2 A1Z7D2 CG2280 PTHR24258:SF134 SERINE PROTEASE-RELATED SUBFAMILY NOT NAMED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0263258|UniProtKB=X2JE77 X2JE77 chas PTHR13585:SF19 CHASCON, ISOFORM D-RELATED CHASCON, ISOFORM D-RELATED DROME|FlyBase=FBgn0030774|UniProtKB=Q9VXC8 Q9VXC8 sphe PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0035724|UniProtKB=Q9VS00 Q9VS00 Dmel\CG10064 PTHR13720:SF14 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0039323|UniProtKB=Q9VBS5 Q9VBS5 Dmel\CG10559 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0051800|UniProtKB=Q8INX1 Q8INX1 Dmel\CG31800 PTHR14553:SF1 UNCHARACTERIZED PROTEIN C1ORF50 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 50 DROME|FlyBase=FBgn0030482|UniProtKB=Q9VYD5 Q9VYD5 Bcat PTHR11825:SF44 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transaminase#PC00216;transferase#PC00220 Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994;Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000 DROME|FlyBase=FBgn0036978|UniProtKB=Q9VPH1 Q9VPH1 Toll-9 PTHR24365:SF530 TOLL-LIKE RECEPTOR TOLL-9, ISOFORM A molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0051272|UniProtKB=Q9VGX6 Q9VGX6 CG6529 PTHR23511:SF36 SYNAPTIC VESICLE GLYCOPROTEIN 2 EG:BACR7A4.13 PROTEIN-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0034814|UniProtKB=Q9W1V7 Q9W1V7 CG9890 PTHR13267:SF3 ZINC FINGER PROTEIN 277 ZINC FINGER PROTEIN 277 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0038789|UniProtKB=Q9VDN3 Q9VDN3 Ir92a PTHR42643:SF40 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 41A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0002842|UniProtKB=Q9VP40 Q9VP40 sa PTHR46469:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667 General transcription by RNA polymerase I#P00022>TAF-IB#P00650;General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>TAF-IC#P00649;General transcription regulation#P00023>TBP-associated factors#P00658;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 DROME|FlyBase=FBgn0037572|UniProtKB=Q8MSM9 Q8MSM9 Dmel\CG11698 PTHR37161:SF2 HDC10475 AT11648P-RELATED DROME|FlyBase=FBgn0030432|UniProtKB=Q9VYI4 Q9VYI4 Dmel\CG4404 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0039310|UniProtKB=Q9VBT8 Q9VBT8 CT33083 PTHR11012:SF13 PROTEIN KINASE-LIKE DOMAIN-CONTAINING AT27361P-RELATED DROME|FlyBase=FBgn0024330|UniProtKB=Q8MSX2 Q8MSX2 MED6 PTHR13104:SF0 MED-6-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0014020|UniProtKB=P48148 P48148 Rho1 PTHR24072:SF398 RHO FAMILY GTPASE RAS-LIKE GTP-BINDING PROTEIN RHO1 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515 cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;cell migration#GO:0016477;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208;G-protein#PC00020 Ras Pathway#P04393>Rho#P04578;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 DROME|FlyBase=FBgn0053301|UniProtKB=Q9VL46 Q9VL46 Dmel\CG33301 PTHR11012:SF13 PROTEIN KINASE-LIKE DOMAIN-CONTAINING AT27361P-RELATED DROME|FlyBase=FBgn0003312|UniProtKB=Q9VGH1 Q9VGH1 sad PTHR24291:SF161 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 315A1, MITOCHONDRIAL mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0004577|UniProtKB=Q01603 Q01603 Pxd PTHR11475:SF86 OXIDASE/PEROXIDASE PEROXIDASE antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 DROME|FlyBase=FBgn0035335|UniProtKB=Q9W021 Q9W021 mRpL23 PTHR12059:SF5 RIBOSOMAL PROTEIN L23-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 DROME|FlyBase=FBgn0041180|UniProtKB=M9PDR0 M9PDR0 Tep4 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494 protease inhibitor#PC00191 DROME|FlyBase=FBgn0015805|UniProtKB=Q94517 Q94517 HDAC1 PTHR10625:SF53 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE HDAC1 deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993;deacylase activity#GO:0160215;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407 biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629 transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233 Wnt signaling pathway#P00057>Histone deacetylase#P01472 DROME|FlyBase=FBgn0033720|UniProtKB=A0A0B4KEL4 A0A0B4KEL4 Dmel\CG13160 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0033233|UniProtKB=Q9V333 Q9V333 Kdm4A PTHR10694:SF142 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4A-RELATED histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;protein demethylase activity#GO:0140457 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0038435|UniProtKB=Q9VEU6 Q9VEU6 Gyc89Da PTHR45655:SF5 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 SOLUBLE GUANYLATE CYCLASE 89DA-RELATED catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;lyase activity#GO:0016829;guanylate cyclase activity#GO:0004383 response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;response to oxygen levels#GO:0070482 cytosol#GO:0005829;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cyclase#PC00079;guanylate cyclase#PC00114 DROME|FlyBase=FBgn0032919|UniProtKB=Q9VIF6 Q9VIF6 pths PTHR24031:SF790 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX47-RELATED ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0015221|UniProtKB=Q9VA83 Q9VA83 Fer2LCH PTHR11431:SF51 FERRITIN FERRITIN LIGHT CHAIN iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 storage protein#PC00210 DROME|FlyBase=FBgn0003941|UniProtKB=P18101 P18101 RpL40 PTHR10666:SF442 UBIQUITIN UBIQUITIN B LIKE 1 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0028421|UniProtKB=Q9VZ07 Q9VZ07 Kap3 PTHR15605:SF2 KINESIN-ASSOCIATED PROTEINS KINESIN-ASSOCIATED PROTEIN 3 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium organization#GO:0044782;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0035488|UniProtKB=Q9VZJ4 Q9VZJ4 anon-EST:Posey64 PTHR12112:SF22 BNIP - RELATED MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 DROME|FlyBase=FBgn0032935|UniProtKB=Q9VIE1 Q9VIE1 Atg18b PTHR11227:SF24 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED AUTOPHAGY-RELATED 18B, ISOFORM A phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;cellular component assembly#GO:0022607;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036118|UniProtKB=Q9VTE0 Q9VTE0 Blos2 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;organelle localization#GO:0051640;transport#GO:0006810;vesicle-mediated transport#GO:0016192;lysosome localization#GO:0032418;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;BLOC-1 complex#GO:0031083;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0032691|UniProtKB=Q9VJ73 Q9VJ73 Atac2 PTHR20916:SF26 CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186 DROME|FlyBase=FBgn0035438|UniProtKB=Q8IRD3 Q8IRD3 Gtpx PTHR11592:SF78 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197 peroxidase#PC00180;oxidoreductase#PC00176 DROME|FlyBase=FBgn0052062|UniProtKB=M9NFQ7 M9NFQ7 Rbfox1 PTHR15597:SF51 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA-BINDING FOX PROTEIN 1, ISOFORM H RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0051091|UniProtKB=Q8IMS3 Q8IMS3 CG5990 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0002524|UniProtKB=Q9V3F2 Q9V3F2 lace PTHR13693:SF3 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE C-PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 transaminase#PC00216 DROME|FlyBase=FBgn0034705|UniProtKB=Q9W280 Q9W280 CG30279 PTHR32073:SF7 GH11358P GH11358P DROME|FlyBase=FBgn0017567|UniProtKB=Q9VF27 Q9VF27 ND-23 PTHR10849:SF20 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 8, MITOCHONDRIAL oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0004391|UniProtKB=Q9VXV3 Q9VXV3 shtd PTHR12827:SF3 MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER ANAPHASE-PROMOTING COMPLEX SUBUNIT 1 regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;protein K11-linked ubiquitination#GO:0070979;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;regulation of chromosome segregation#GO:0051983;metaphase/anaphase transition of cell cycle#GO:0044784;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;modification-dependent protein catabolic process#GO:0019941;cell cycle#GO:0007049;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;mitotic cell cycle phase transition#GO:0044772;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0027785|UniProtKB=Q9V3L7 Q9V3L7 NP15.6 PTHR13327:SF0 NADH-UBIQUINONE OXIDOREDUCTASE ESSS SUBUNIT, MITOCHONDRIAL PRECURSOR NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 11, MITOCHONDRIAL catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0030969|UniProtKB=Q9VWP1 Q9VWP1 Usp39 PTHR21646:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 39 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;regulation of protein stability#GO:0031647;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 cysteine protease#PC00081 DROME|FlyBase=FBgn0032042|UniProtKB=Q9VLL4 Q9VLL4 Dmel\CG13398 PTHR21258:SF55 DOCKING PROTEIN RELATED FI23523P1 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;fibroblast growth factor receptor binding#GO:0005104;receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;growth factor receptor binding#GO:0070851 signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;response to fibroblast growth factor#GO:0071774;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032067|UniProtKB=Q9VLI1 Q9VLI1 LManIV PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 glycosidase#PC00110;hydrolase#PC00121 DROME|FlyBase=FBgn0263233|UniProtKB=Q6IG91 Q6IG91 robls54B PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0051678|UniProtKB=Q9VIK7 Q9VIK7 CG17465 PTHR12953:SF0 MEMBRANE PROTEIN CH1 RELATED LD18032P membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 structural protein#PC00211 DROME|FlyBase=FBgn0033235|UniProtKB=Q7K3W2 Q7K3W2 Mppa PTHR11851:SF229 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endopeptidase complex#GO:1905369 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0031636|UniProtKB=E1JHT4 E1JHT4 anon-EST:Posey105 PTHR23512:SF13 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LYSOSOMAL DIPEPTIDE TRANSPORTER MFSD1 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0027492|UniProtKB=A0A6F7R657 A0A6F7R657 wdb PTHR10257:SF5 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B WIDERBORST, ISOFORM H enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 negative regulation of cell communication#GO:0010648;sister chromatid cohesion#GO:0007062;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell cycle#GO:0007049;negative regulation of biological process#GO:0048519;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;organelle organization#GO:0006996 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 DROME|FlyBase=FBgn0033868|UniProtKB=Q500X4 Q500X4 S-Lap7 PTHR11963:SF16 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0000639|UniProtKB=Q04691 Q04691 Fbp1 PTHR11511:SF5 LARVAL STORAGE PROTEIN/PHENOLOXIDASE FAT-BODY PROTEIN 1-RELATED DROME|FlyBase=FBgn0040078|UniProtKB=Q9VH07 Q9VH07 pont PTHR11093:SF6 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 1 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ribonucleoprotein complex biogenesis#GO:0022613;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of DNA-templated transcription#GO:0006355;protein-RNA complex assembly#GO:0022618;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;protein-containing complex organization#GO:0043933 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0036170|UniProtKB=Q9VTJ5 Q9VTJ5 CG33047 PTHR24410:SF51 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN-RELATED defense/immunity protein#PC00090 DROME|FlyBase=FBgn0037074|UniProtKB=Q9VP46 Q9VP46 Tbc1d8-9 PTHR22957:SF661 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN GH16847P molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0261955|UniProtKB=Q9W401 Q9W401 Cs1 PTHR11739:SF8 CITRATE SYNTHASE CITRATE SYNTHASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 carbohydrate metabolic process#GO:0005975;cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Citrate Synthetase#P03141;TCA cycle#P00051>Citrate Synthase#P01267 DROME|FlyBase=FBgn0263144|UniProtKB=Q7K480 Q7K480 bin3 PTHR12315:SF0 BICOID-INTERACTING PROTEIN RELATED 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;snRNA binding#GO:0017069;RNA binding#GO:0003723;O-methyltransferase activity#GO:0008171;binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073 DROME|FlyBase=FBgn0024983|UniProtKB=O76896 O76896 EG:65F1.1 PTHR10984:SF30 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2 transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020 DROME|FlyBase=FBgn0036594|UniProtKB=Q9VV18 Q9VV18 Dmel\CG13047 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0033867|UniProtKB=Q7JZ94 Q7JZ94 Cpr50Ca PTHR12236:SF100 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 50CA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0011591|UniProtKB=Q24342 Q24342 fng PTHR10811:SF134 FRINGE-RELATED FRINGE GLYCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593 transferase#PC00220;glycosyltransferase#PC00111 Notch signaling pathway#P00045>Fringe#P01107 DROME|FlyBase=FBgn0025686|UniProtKB=Q9VPN2 Q9VPN2 Amnionless PTHR14995:SF2 AMNIONLESS PROTEIN AMNIONLESS receptor-mediated endocytosis#GO:0006898;intracellular protein localization#GO:0008104;system process#GO:0003008;import into cell#GO:0098657;establishment of localization#GO:0051234;renal absorption#GO:0070293;localization#GO:0051179;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;cellular process#GO:0009987;renal system process#GO:0003014;macromolecule localization#GO:0033036 apical part of cell#GO:0045177;signaling receptor complex#GO:0043235;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982 DROME|FlyBase=FBgn0032271|UniProtKB=Q9VKT2 Q9VKT2 Dmel\CG7329 PTHR11005:SF144 LYSOSOMAL ACID LIPASE-RELATED AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0032253|UniProtKB=Q9VKV2 Q9VKV2 LManI PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;hydrolase#PC00121 DROME|FlyBase=FBgn0039200|UniProtKB=Q9VC75 Q9VC75 Dmel\CG13616 PTHR21398:SF7 AGAP007094-PA LP19941P DROME|FlyBase=FBgn0035078|UniProtKB=Q9W0Y9 Q9W0Y9 Tpc2 PTHR24089:SF59 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER organophosphate ester transmembrane transporter activity#GO:0015605;quaternary ammonium group transmembrane transporter activity#GO:0015651;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 vitamin transport#GO:0051180;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 DROME|FlyBase=FBgn0261710|UniProtKB=Q9W2U7 Q9W2U7 nocte PTHR14038:SF0 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 LP18708P RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0025592|UniProtKB=Q9W0U0 Q9W0U0 Gk1 PTHR10196:SF82 SUGAR KINASE GLYCEROL KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 carbohydrate kinase#PC00065;kinase#PC00137 DROME|FlyBase=FBgn0039252|UniProtKB=Q9VC06 Q9VC06 Dmel\CG11771 PTHR11804:SF86 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED LD37516P catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0034447|UniProtKB=A1ZBL2 A1ZBL2 Dmel\CG7744 PTHR28646:SF2 TRANSMEMBRANE PROTEIN 201 FI17509P1 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;nuclear migration#GO:0007097 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967 DROME|FlyBase=FBgn0004644|UniProtKB=Q02936 Q02936 hh PTHR11889:SF86 HEDGEHOG PROTEIN HEDGEHOG calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;smoothened signaling pathway#GO:0007224;cell fate commitment#GO:0045165;cell communication#GO:0007154;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cell surface receptor signaling pathway#GO:0007166;cell fate specification#GO:0001708;developmental process#GO:0032502 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Hedgehog signaling pathway#P00025>Hedgehog#P00688 DROME|FlyBase=FBgn0032433|UniProtKB=Q9VK84 Q9VK84 Oatp33Ea PTHR11388:SF131 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0036787|UniProtKB=Q9VVP9 Q9VVP9 Dmel\CG4306 PTHR12935:SF0 GAMMA-GLUTAMYLCYCLOTRANSFERASE GAMMA-GLUTAMYLCYCLOTRANSFERASE lyase activity#GO:0016829;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0029157|UniProtKB=Q6NN85 Q6NN85 ssh PTHR45864:SF2 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;actin binding#GO:0003779;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;cytoskeletal protein binding#GO:0008092;phosphatase activity#GO:0016791 regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 DROME|FlyBase=FBgn0034158|UniProtKB=Q0E949 Q0E949 RalGPS PTHR23113:SF374 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;intracellular signaling cassette#GO:0141124;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;Ras protein signal transduction#GO:0007265;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0001078|UniProtKB=P33244 P33244 ftz-f1 PTHR24086:SF15 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NUCLEAR HORMONE RECEPTOR FTZ-F1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0039311|UniProtKB=Q9VBT7 Q9VBT7 Dmel\CG10513 PTHR11012:SF13 PROTEIN KINASE-LIKE DOMAIN-CONTAINING AT27361P-RELATED DROME|FlyBase=FBgn0037760|UniProtKB=Q9VH60 Q9VH60 FBXO11 PTHR22990:SF20 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0022097|UniProtKB=Q9V7D2 Q9V7D2 Vha36-1 PTHR11671:SF5 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of intracellular pH#GO:0051453;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;regulation of pH#GO:0006885;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;vacuolar acidification#GO:0007035 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 ATP synthase#PC00002 DROME|FlyBase=FBgn0035103|UniProtKB=Q0E8K8 Q0E8K8 Vdup1 PTHR11188:SF179 ARRESTIN DOMAIN CONTAINING PROTEIN FI21816P1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0029507|UniProtKB=Q7JWV7 Q7JWV7 Tsp42Ed PTHR19282:SF521 TETRASPANIN AT12771P-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0052201|UniProtKB=Q8IQS7 Q8IQS7 CG13382 PTHR10869:SF216 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROCOLLAGEN-PROLINE 4-DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 oxidoreductase complex#GO:1990204;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0025549|UniProtKB=Q9XYQ2 Q9XYQ2 unc-119 PTHR12951:SF1 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG lipid binding#GO:0008289;binding#GO:0005488 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;localization#GO:0051179;protein transport#GO:0015031;cilium organization#GO:0044782;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0020626|UniProtKB=Q9VC05 Q9VC05 Osbp PTHR10972:SF205 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 1 binding#GO:0005488;sterol binding#GO:0032934;lipid binding#GO:0008289;steroid binding#GO:0005496 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0035429|UniProtKB=Q9VZR7 Q9VZR7 Dmel\CG12017 PTHR48209:SF2 AGL056WP FI24008P1 DROME|FlyBase=FBgn0037100|UniProtKB=Q8ITC7 Q8ITC7 CapaR PTHR24243:SF241 G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDES CAPA RECEPTOR signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0063493|UniProtKB=A1ZB72 A1ZB72 GstE7 PTHR43969:SF4 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED FI01423P-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 DROME|FlyBase=FBgn0027101|UniProtKB=P83102 P83102 Dyrk3 PTHR24058:SF112 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 HOMOLOG-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030847|UniProtKB=M9PJQ1 M9PJQ1 Dmel\CG12991 PTHR16021:SF13 MANSC DOMAIN CONTAINING PROTEIN 1 EARTHBOUND 1-RELATED DROME|FlyBase=FBgn0024248|UniProtKB=Q9XTN2 Q9XTN2 chico PTHR10614:SF13 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 1 receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;binding#GO:0005488;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;insulin-like growth factor receptor signaling pathway#GO:0048009;response to stimulus#GO:0050896;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 PI3 kinase pathway#P00048>IRS#P01193;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887 DROME|FlyBase=FBgn0030344|UniProtKB=Q9VYT3 Q9VYT3 Nrd1 PTHR43690:SF40 NARDILYSIN NARDILYSIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 DROME|FlyBase=FBgn0051211|UniProtKB=Q86B99 Q86B99 CG18546 PTHR31518:SF3 ARGININE/SERINE-RICH PROTEIN PNISR ARGININE_SERINE-RICH PROTEIN PNISR DROME|FlyBase=FBgn0002736|UniProtKB=P49028 P49028 mago PTHR12638:SF0 PROTEIN MAGO NASHI HOMOLOG MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing#GO:0008380;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 DROME|FlyBase=FBgn0000808|UniProtKB=O62589 O62589 gd PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0052823|UniProtKB=Q8IRZ3 Q8IRZ3 Sdic3 PTHR12442:SF22 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;microtubule-based transport#GO:0099111;intracellular transport#GO:0046907;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0031474|UniProtKB=Q9VQI2 Q9VQI2 CT42388 PTHR20893:SF2 LD08641P LD08641P DROME|FlyBase=FBgn0264693|UniProtKB=A8JNK1 A8JNK1 ens PTHR15073:SF19 MICROTUBULE-ASSOCIATED PROTEIN ENSCONSIN, ISOFORM F biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0003360|UniProtKB=Q26365 Q26365 sesB PTHR45635:SF56 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008;transport#GO:0006810;organophosphate ester transport#GO:0015748;regulation of membrane permeability#GO:0090559;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0052704|UniProtKB=Q9W365 Q9W365 Ir8a PTHR18966:SF403 IONOTROPIC GLUTAMATE RECEPTOR IONOTROPIC RECEPTOR CORECEPTOR IR8A gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0030467|UniProtKB=Q9VYF0 Q9VYF0 Dmel\CG1764 PTHR12737:SF9 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE GM09012P hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;biological regulation#GO:0065007;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of biological process#GO:0050789 hydrolase#PC00121 DROME|FlyBase=FBgn0052755|UniProtKB=Q8IRR3 Q8IRR3 Dmel\CG32755 PTHR24253:SF201 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033373|UniProtKB=A0A0B4KEG0 A0A0B4KEG0 Nadk2 PTHR13158:SF5 FAMILY NOT NAMED NAD KINASE 2, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521 DROME|FlyBase=FBgn0010398|UniProtKB=Q9VKU0 Q9VKU0 Lrr47 PTHR45752:SF13 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 58 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0003719|UniProtKB=P25723 P25723 tld PTHR10127:SF911 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING DORSAL-VENTRAL PATTERNING PROTEIN TOLLOID-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 pattern specification process#GO:0007389;proteolysis#GO:0006508;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;dorsal/ventral pattern formation#GO:0009953;primary metabolic process#GO:0044238;developmental process#GO:0032502;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;regionalization#GO:0003002;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 SCW signaling pathway#P06216>TLD#P06327;TGF-beta signaling pathway#P00052>TGFbeta#P01286;DPP signaling pathway#P06213>TLD#P06283;BMP/activin signaling pathway-drosophila#P06211>TLD#P06249;DPP-SCW signaling pathway#P06212>TLD#P06264 DROME|FlyBase=FBgn0037418|UniProtKB=Q9VNN1 Q9VNN1 Osi11 PTHR21879:SF7 FI03362P-RELATED-RELATED OSIRIS 11 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0030654|UniProtKB=Q9VXT6 Q9VXT6 CG32583 PTHR13481:SF0 SREBP REGULATING GENE PROTEIN SREBP REGULATING GENE PROTEIN DROME|FlyBase=FBgn0029905|UniProtKB=Q9W3V9 Q9W3V9 Nf-YC PTHR10252:SF156 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 DROME|FlyBase=FBgn0038079|UniProtKB=A8JQY7 A8JQY7 NijC PTHR12316:SF29 NINJURIN-RELATED NINJURIN C, ISOFORM D cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515 programmed cell death#GO:0012501;cell adhesion#GO:0007155;cellular process#GO:0009987;cell death#GO:0008219 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0032843|UniProtKB=Q9VIP6 Q9VIP6 Dmel\CG10730 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0046296|UniProtKB=Q9VTT9 Q9VTT9 DEF8 PTHR12326:SF3 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN DIFFERENTIALLY EXPRESSED IN FDCP 8 HOMOLOG DROME|FlyBase=FBgn0037164|UniProtKB=Q9VNU1 Q9VNU1 WUN-like PTHR10165:SF103 LIPID PHOSPHATE PHOSPHATASE FI04477P-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;cell communication#GO:0007154;dephosphorylation#GO:0016311;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0250874|UniProtKB=Q9W4V8 Q9W4V8 ttm50 PTHR12210:SF3 DULLARD PROTEIN PHOSPHATASE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 protein phosphatase#PC00195 DROME|FlyBase=FBgn0037004|UniProtKB=Q9VPD9 Q9VPD9 Dmel\CG17637 PTHR23504:SF1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 GH21943P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0010434|UniProtKB=Q9V8R9 Q9V8R9 cora PTHR23280:SF21 4.1 G PROTEIN PROTEIN 4.1 HOMOLOG cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0031294|UniProtKB=Q9VPV8 Q9VPV8 IA-2 PTHR46106:SF4 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C regulation of secretion#GO:0051046;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789 cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982 protein phosphatase#PC00195 DROME|FlyBase=FBgn0038366|UniProtKB=Q9VF31 Q9VF31 Dmel\CG4576 PTHR11161:SF22 O-ACYLTRANSFERASE ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0030657|UniProtKB=Q9VXT3 Q9VXT3 cerv PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;protein modification by small protein conjugation or removal#GO:0070647 condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0001198|UniProtKB=P02283 P02283 His2B PTHR23428:SF70 HISTONE H2B HISTONE H2B chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0033584|UniProtKB=A0A0B4LET0 A0A0B4LET0 Dmel\CG7737 PTHR10742:SF398 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidase#PC00175 DROME|FlyBase=FBgn0034538|UniProtKB=A1ZBX6 A1ZBX6 Dmel\CG16799 PTHR11407:SF75 LYSOZYME C LYSOZYME hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;lysozyme activity#GO:0003796;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycosidase#PC00110 DROME|FlyBase=FBgn0050441|UniProtKB=A1Z6F0 A1Z6F0 IFT20 PTHR31978:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG INTRAFLAGELLAR TRANSPORT 20 cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;cellular component organization#GO:0016043;cilium assembly#GO:0060271 ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0030703|UniProtKB=Q9VXM4 Q9VXM4 MSBP PTHR10281:SF106 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED IP06960P-RELATED membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0031896|UniProtKB=Q9VM35 Q9VM35 CG4502 PTHR24068:SF72 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2Q-LIKE PROTEIN 1 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0037110|UniProtKB=Q9VP04 Q9VP04 ORMDL PTHR12665:SF7 ORMDL PROTEINS ORM1-LIKE PROTEIN lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;ceramide metabolic process#GO:0006672;cellular process#GO:0009987;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;homeostatic process#GO:0042592 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0034734|UniProtKB=Q9W246 Q9W246 Dmel\CG4554 PTHR17695:SF11 SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0030384|UniProtKB=Q9VYN5 Q9VYN5 Dmel\CG2577 PTHR11909:SF428 CASEIN KINASE-RELATED DISCS OVERGROWN PROTEIN KINASE-RELATED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;cell communication#GO:0007154;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;positive regulation of Wnt signaling pathway#GO:0030177;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242 DROME|FlyBase=FBgn0003386|UniProtKB=P17972 P17972 Shaw PTHR11537:SF294 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAW voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 metal ion transport#GO:0030001;action potential#GO:0001508;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;axon terminus#GO:0043679;membrane#GO:0016020;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054;cell leading edge#GO:0031252;presynapse#GO:0098793;neuron projection#GO:0043005;protein-containing complex#GO:0032991;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;postsynapse#GO:0098794;cell body#GO:0044297;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995 voltage-gated ion channel#PC00241;ion channel#PC00133 DROME|FlyBase=FBgn0032154|UniProtKB=Q9VL76 Q9VL76 mtDNA-helicase PTHR12873:SF7 T7-LIKE MITOCHONDRIAL DNA HELICASE TWINKLE MTDNA HELICASE DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA helicase#PC00011 DROME|FlyBase=FBgn0037336|UniProtKB=Q9VNC9 Q9VNC9 Dmel\CG2519 PTHR37686:SF1 LD36006P LD36006P DROME|FlyBase=FBgn0036020|UniProtKB=Q9VT21 Q9VT21 Cyp40 PTHR11071:SF497 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYCLOPHILIN 40, ISOFORM A ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 DROME|FlyBase=FBgn0033139|UniProtKB=Q1EC46 Q1EC46 Tsp42Er PTHR19282:SF521 TETRASPANIN AT12771P-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0267350|UniProtKB=M9PDM4 M9PDM4 Pi4KIIIalpha PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 kinase#PC00137 DROME|FlyBase=FBgn0033650|UniProtKB=A1Z8P1 A1Z8P1 Dmel\CG13193 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0031068|UniProtKB=C0PVB3 C0PVB3 Alr PTHR12645:SF0 ALR/ERV SULFHYDRYL OXIDASE nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;disulfide oxidoreductase activity#GO:0015036 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0266268|UniProtKB=Q9V9S8 Q9V9S8 FeCh PTHR11108:SF1 FERROCHELATASE FERROCHELATASE, MITOCHONDRIAL catalytic activity#GO:0003824;lyase activity#GO:0016829 porphyrin-containing compound biosynthetic process#GO:0006779;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 lyase#PC00144 Heme biosynthesis#P02746>Ferrochelatase#P02972 DROME|FlyBase=FBgn0036534|UniProtKB=Q5U127 Q5U127 DCP2 PTHR23114:SF17 M7GPPPN-MRNA HYDROLASE M7GPPPN-MRNA HYDROLASE catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0041624|UniProtKB=P82983 P82983 Or65b PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0032649|UniProtKB=Q9VJC3 Q9VJC3 Dmel\CG15145 PTHR22455:SF10 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 DROME|FlyBase=FBgn0035686|UniProtKB=Q9VRU9 Q9VRU9 Cpr65Az PTHR10380:SF242 CUTICLE PROTEIN CUTICULAR PROTEIN 47EG-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0032988|UniProtKB=Q9V9M6 Q9V9M6 Tif-IA PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription initiation at RNA polymerase I promoter#GO:0006361;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 DROME|FlyBase=FBgn0039862|UniProtKB=A0A0B4KHL5 A0A0B4KHL5 kek6 PTHR24366:SF87 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS KEKKON 6, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0000251|UniProtKB=P09085 P09085 cad PTHR24332:SF9 HOMEOBOX PROTEIN CDX HOMEOTIC PROTEIN CAUDAL double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tube development#GO:0035295;embryo development#GO:0009790;regulation of primary metabolic process#GO:0080090;embryonic pattern specification#GO:0009880;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;anterior/posterior axis specification#GO:0009948;regulation of gene expression#GO:0010468;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0033174|UniProtKB=Q6NMT8 Q6NMT8 Dmel\CG11125 PTHR21490:SF2 ENKURIN-RELATED ENKURIN DOMAIN-CONTAINING PROTEIN 1 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0053641|UniProtKB=Q4ABG0 Q4ABG0 Dmel\CG33641 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0037447|UniProtKB=Q9VI25 Q9VI25 Neurochondrin PTHR13109:SF8 NEUROCHONDRIN NEUROCHONDRIN cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of synaptic plasticity#GO:0048167;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856 plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;neuron projection#GO:0043005;dendrite#GO:0030425 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0003118|UniProtKB=P51023 P51023 pnt PTHR11849:SF289 ETS ETS-LIKE PROTEIN POINTED transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 DROME|FlyBase=FBgn0037162|UniProtKB=Q9VNU3 Q9VNU3 Dmel\CG11449 PTHR15504:SF0 NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45 regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of cell motility#GO:2000145;regulation of microtubule-based process#GO:0032886 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881 DROME|FlyBase=FBgn0029870|UniProtKB=Q7YU24 Q7YU24 Marf PTHR10465:SF3 TRANSMEMBRANE GTPASE FZO1 TRANSMEMBRANE GTPASE MARF-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;mitochondrion localization#GO:0051646;organelle localization#GO:0051640;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular process#GO:0009987 organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0036306|UniProtKB=Q95RI2 Q95RI2 Dmel\CG10973 PTHR19316:SF35 PROTEIN FOLDING REGULATOR NUCLEOTIDE EXCHANGE FACTOR SIL1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0286070|UniProtKB=Q7KNQ9 Q7KNQ9 cnk PTHR12844:SF42 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KSR PROTEIN CNK structural molecule activity#GO:0005198;MAP kinase scaffold activity#GO:0005078;signaling adaptor activity#GO:0035591;protein complex scaffold activity#GO:0140378;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051115|UniProtKB=Q8IMU4 Q8IMU4 CG31115 PTHR42679:SF2 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 Purine metabolism#P02769>Nucleoside Phosphorylase#P03115 DROME|FlyBase=FBgn0033904|UniProtKB=A1Z9L9 A1Z9L9 Dmel\CG18327 PTHR45928:SF1 RE38146P RE38146P DROME|FlyBase=FBgn0023179|UniProtKB=Q9VBC7 Q9VBC7 amon PTHR42884:SF13 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 2 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 peptide hormone processing#GO:0016486;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;hormone metabolic process#GO:0042445;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;proteolysis#GO:0006508;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;neuron projection#GO:0043005;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 DROME|FlyBase=FBgn0039558|UniProtKB=Q9VAY6 Q9VAY6 BCAS2 PTHR13296:SF0 BCAS2 PROTEIN PRE-MRNA-SPLICING FACTOR SPF27 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0031972|UniProtKB=Q9VLU5 Q9VLU5 Wwox PTHR24320:SF292 RETINOL DEHYDROGENASE WW DOMAIN-CONTAINING OXIDOREDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0035524|UniProtKB=Q9VZE6 Q9VZE6 CG11583 PTHR13634:SF0 RIBOSOME BIOGENESIS PROTEIN BRIX RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;ribosomal large subunit assembly#GO:0000027;protein-RNA complex assembly#GO:0022618;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0036706|UniProtKB=Q9VVF0 Q9VVF0 ND-24L PTHR10371:SF3 NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176;dehydrogenase#PC00092 Parkinson disease#P00049>Complex I#P01237 DROME|FlyBase=FBgn0028539|UniProtKB=Q0E8Q7 Q0E8Q7 Eato PTHR19229:SF278 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0023531|UniProtKB=Q7KW14 Q7KW14 CG32809 PTHR22741:SF10 P140CAP/SNIP-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN CG32809 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0033558|UniProtKB=Q8SWZ1 Q8SWZ1 alka PTHR18945:SF802 NEUROTRANSMITTER GATED ION CHANNEL RH55021P excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0031858|UniProtKB=Q9VM87 Q9VM87 Dmel\CG17378 PTHR13663:SF2 SIMILAR TO RIKEN CDNA 6430548M08 RIKEN CDNA 6430548M08 GENE LIKE DROME|FlyBase=FBgn0259736|UniProtKB=A0A6H2EFV6 A0A6H2EFV6 Dmel\CG42390 PTHR23138:SF142 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 2 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051814|UniProtKB=Q8IP70 Q8IP70 DIP-kappa PTHR12231:SF278 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN KAPPA, ISOFORM A binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;cell adhesion#GO:0007155;synapse organization#GO:0050808 cell projection membrane#GO:0031253;cell junction#GO:0030054;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0033744|UniProtKB=E2QCM9 E2QCM9 Dh44-R2 PTHR45620:SF15 PDF RECEPTOR-LIKE PROTEIN-RELATED DIURETIC HORMONE RECEPTOR hormone binding#GO:0042562;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0039054|UniProtKB=Q9VCR3 Q9VCR3 Cow PTHR12352:SF25 SECRETED MODULAR CALCIUM-BINDING PROTEIN TESTICAN-1 establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 calmodulin-related#PC00061 DROME|FlyBase=FBgn0243486|UniProtKB=X2J6K6 X2J6K6 rdo PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0037727|UniProtKB=Q9VH96 Q9VH96 Nepl12 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0005779|UniProtKB=Q9VQL9 Q9VQL9 PpD6 PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE-RELATED phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 DROME|FlyBase=FBgn0035247|UniProtKB=Q86BS6 Q86BS6 Mettl2 PTHR22809:SF11 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 methyltransferase#PC00155 DROME|FlyBase=FBgn0039688|UniProtKB=Q9VAI2 Q9VAI2 Kul PTHR45702:SF3 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;biological regulation#GO:0065007;membrane protein ectodomain proteolysis#GO:0006509;proteolysis#GO:0006508;cell communication#GO:0007154;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 DROME|FlyBase=FBgn0031987|UniProtKB=Q9VLS9 Q9VLS9 CG12375 PTHR23131:SF6 ENDORIBONUCLEASE LACTB2 ENDORIBONUCLEASE LACTB2 nuclease activity#GO:0004518;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0042137|UniProtKB=Q9I7R3 Q9I7R3 Dmel\CG18814 PTHR44229:SF8 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] ALCOHOL DEHYDROGENASE-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0031630|UniProtKB=Q9VR28 Q9VR28 Dmel\CG15629 PTHR24322:SF729 PKSB MIP05442P oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 DROME|FlyBase=FBgn0029801|UniProtKB=Q9W481 Q9W481 Nanp PTHR46470:SF3 N-ACYLNEURAMINATE-9-PHOSPHATASE N-ACYLNEURAMINATE-9-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0052280|UniProtKB=Q8IRE5 Q8IRE5 BcDNA:GM08588 PTHR23292:SF6 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16602P1-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039584|UniProtKB=Q9VAV8 Q9VAV8 beat-VI PTHR21261:SF17 BEAT PROTEIN BEAT VI intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0039817|UniProtKB=Q9VA14 Q9VA14 Dmel\CG15553 PTHR23507:SF39 ZGC:174356 GH23453P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0032321|UniProtKB=Q9VKM6 Q9VKM6 YL-1 PTHR13275:SF4 YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0038256|UniProtKB=Q9VFG7 Q9VFG7 Dmel\CG7530 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to Golgi apparatus#GO:0034067;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034554|UniProtKB=Q9W2R0 Q9W2R0 CAH14 PTHR18952:SF233 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 14 hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0031026|UniProtKB=Q9VWH2 Q9VWH2 Dmel\CG12231 PTHR12378:SF80 DESUMOYLATING ISOPEPTIDASE IP06716P-RELATED deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0086674|UniProtKB=Q9VYB7 Q9VYB7 Tpst PTHR12788:SF10 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 DROME|FlyBase=FBgn0037240|UniProtKB=Q9VN14 Q9VN14 Cont PTHR10075:SF83 BASIGIN RELATED CONTACTIN cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0016756|UniProtKB=Q24574 Q24574 Usp47 PTHR24006:SF702 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 DROME|FlyBase=FBgn0004117|UniProtKB=P09491 P09491 Tm2 PTHR19269:SF53 TROPOMYOSIN TROPOMYOSIN-2 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;muscle system process#GO:0003012 supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884 actin binding motor protein#PC00040 DROME|FlyBase=FBgn0030206|UniProtKB=Q9W2U6 Q9W2U6 Dmel\CG2889 PTHR23225:SF2 ZINC FINGER PROTEIN AT09679P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0015300|UniProtKB=Q24536 Q24536 Ssl PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;serine/threonine protein kinase complex#GO:1902554;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0039244|UniProtKB=Q8MRJ2 Q8MRJ2 Dmel\CG11069 PTHR48041:SF144 ABC TRANSPORTER G FAMILY MEMBER 28 LD11139P sterol transfer activity#GO:0120015;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;cholesterol transfer activity#GO:0120020;primary active transmembrane transporter activity#GO:0015399;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid transfer activity#GO:0120013 cellular process#GO:0009987;cholesterol efflux#GO:0033344;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;lipid transport#GO:0006869;chemical homeostasis#GO:0048878;transport#GO:0006810;sterol transport#GO:0015918;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;ATP-binding cassette (ABC) transporter complex#GO:0043190;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0011224|UniProtKB=A0A0B4K6W9 A0A0B4K6W9 heph PTHR15592:SF14 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HEPHAESTUS, ISOFORM Y RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 DROME|FlyBase=FBgn0036947|UniProtKB=Q9VW89 Q9VW89 obst-F PTHR23301:SF114 CHITIN BINDING PERITROPHIN-A LP10853P binding#GO:0005488;carbohydrate derivative binding#GO:0097367 external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035620|UniProtKB=Q9VRM9 Q9VRM9 Alp9 PTHR11596:SF85 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0029093|UniProtKB=Q7K485 Q7K485 cathD PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987 aspartic protease#PC00053;protease#PC00190 DROME|FlyBase=FBgn0033429|UniProtKB=A1Z7W3 A1Z7W3 Dmel\CG12929 PTHR28668:SF1 TRANSMEMBRANE PROTEIN 234 TRANSMEMBRANE PROTEIN 234 DROME|FlyBase=FBgn0034552|UniProtKB=Q9W2R2 Q9W2R2 Dmel\CG17999 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436 ligase#PC00142 DROME|FlyBase=FBgn0000274|UniProtKB=P16911 P16911 Pka-C2 PTHR24353:SF152 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE UT01108P-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437 DROME|FlyBase=FBgn0050373|UniProtKB=A1Z7B8 A1Z7B8 Dmel\CG30373 PTHR35268:SF1 PROTEIN CCSMST1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 4 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0037894|UniProtKB=Q9VGP4 Q9VGP4 Ipo9 PTHR10997:SF9 IMPORTIN-7, 8, 11 IMPORTIN-9 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 DROME|FlyBase=FBgn0040349|UniProtKB=Q9U1L2 Q9U1L2 EG:BACR7A4.14 PTHR43975:SF6 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED DROME|FlyBase=FBgn0261393|UniProtKB=A0A0B4K6V8 A0A0B4K6V8 alpha-Est5 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0027499|UniProtKB=Q7KMH9 Q7KMH9 wde PTHR23210:SF26 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0264691|UniProtKB=Q9W328 Q9W328 Lst8 PTHR19842:SF0 G BETA-LIKE PROTEIN GBL TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of actin filament-based process#GO:0032970;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;TOR signaling#GO:0031929;regulation of actin cytoskeleton organization#GO:0032956 protein-containing complex#GO:0032991;TOR complex#GO:0038201;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0025814|UniProtKB=Q8SY19 Q8SY19 Mgstl PTHR10689:SF6 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0014010|UniProtKB=Q9V3I2 Q9V3I2 Rab5 PTHR24073:SF1240 DRAB5-RELATED RAS-RELATED PROTEIN RAB5 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;endocytosis#GO:0006897;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0002522|UniProtKB=P10105 P10105 lab PTHR45946:SF4 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN ROUGH-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0027525|UniProtKB=Q7KN79 Q7KN79 LTV1 PTHR21531:SF0 LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED PROTEIN LTV1 HOMOLOG cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;ribosomal small subunit biogenesis#GO:0042274;transport#GO:0006810;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0085452|UniProtKB=E1JGT3 E1JGT3 Dmel\CG34423 PTHR48417:SF1 ATP SYNTHASE F1 SUBUNIT EPSILON ATPASE INHIBITOR, MITOCHONDRIAL molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0031673|UniProtKB=Q7K1W8 Q7K1W8 CG9112 PTHR10827:SF78 RETICULOCALBIN RETICULOCALBIN-2 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0003317|UniProtKB=A0A0B4K7J3 A0A0B4K7J3 sax PTHR23255:SF109 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE protein kinase activity#GO:0004672;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;regionalization#GO:0003002;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;cell differentiation#GO:0030154;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;dorsal/ventral pattern formation#GO:0009953;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;pattern specification process#GO:0007389 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 serine/threonine protein kinase receptor#PC00205 BMP/activin signaling pathway-drosophila#P06211>TGFbetaR I#P06241;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;GBB signaling pathway#P06214>SAX#P06307;SCW signaling pathway#P06216>SAX#P06329;DPP-SCW signaling pathway#P06212>SAX#P06274;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 DROME|FlyBase=FBgn0026189|UniProtKB=P82295 P82295 promL PTHR22730:SF1 PROMININ PROM PROTEIN PROMININ-LIKE PROTEIN cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoskeleton#GO:0005856;apical part of cell#GO:0045177;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;extracellular region#GO:0005576;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 DROME|FlyBase=FBgn0015283|UniProtKB=P55035 P55035 Rpn10 PTHR10223:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488;protein binding#GO:0005515 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 protease#PC00190;protein modifying enzyme#PC00260 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0051792|UniProtKB=Q9VJ21 Q9VJ21 CG17338 PTHR24223:SF448 ATP-BINDING CASSETTE SUB-FAMILY C FI20146P1-RELATED transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 ATP-binding cassette (ABC) transporter#PC00003 DROME|Gene_ORFName=Dmel_CG46519|UniProtKB=A0ACD4DAV5 A0ACD4DAV5 CG46519 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;protein-containing complex assembly#GO:0065003;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0040102|UniProtKB=Q9VQX3 Q9VQX3 lectin-24Db PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN binding#GO:0005488;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0051244|UniProtKB=Q9VDX4 Q9VDX4 CG18491 PTHR12532:SF12 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0020378|UniProtKB=M9PJG1 M9PJG1 Sp1 PTHR23235:SF207 KRUEPPEL-LIKE TRANSCRIPTION FACTOR SP1, ISOFORM F sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 Huntington disease#P00029>Sp1#P00803 DROME|FlyBase=FBgn0033519|UniProtKB=A0A0B4KEI1 A0A0B4KEI1 Dmel\CG11825 PTHR12297:SF21 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN-CONTAINING PROTEIN cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0263111|UniProtKB=P91645 P91645 cac PTHR45628:SF40 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 monoatomic cation transmembrane transport#GO:0098655;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;synaptic signaling#GO:0099536;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;transport#GO:0006810;metal ion transport#GO:0030001;signaling#GO:0023052;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;chemical synaptic transmission#GO:0007268;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022 DROME|FlyBase=FBgn0032631|UniProtKB=Q6IH99 Q6IH99 Dmel\CG15140 PTHR39956:SF1 GH09530P-RELATED GH09530P-RELATED DROME|FlyBase=FBgn0004885|UniProtKB=Q9VC47 Q9VC47 tok PTHR10127:SF911 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING DORSAL-VENTRAL PATTERNING PROTEIN TOLLOID-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;regionalization#GO:0003002;biosynthetic process#GO:0009058;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;metabolic process#GO:0008152;developmental process#GO:0032502;primary metabolic process#GO:0044238;dorsal/ventral pattern formation#GO:0009953;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;proteolysis#GO:0006508;pattern specification process#GO:0007389 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 SCW signaling pathway#P06216>TLD#P06327;TGF-beta signaling pathway#P00052>TGFbeta#P01286;DPP signaling pathway#P06213>TLD#P06283;BMP/activin signaling pathway-drosophila#P06211>TLD#P06249;DPP-SCW signaling pathway#P06212>TLD#P06264 DROME|FlyBase=FBgn0037409|UniProtKB=Q9VNM2 Q9VNM2 Osi24 PTHR21879:SF25 FI03362P-RELATED-RELATED OSIRIS 24 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0002924|UniProtKB=P20480 P20480 ncd PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0030571|UniProtKB=X2JBU2 X2JBU2 BcDNA:AT01764 PTHR21245:SF2 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 18-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037248|UniProtKB=Q8IPM1 Q8IPM1 srl PTHR15528:SF11 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED FI18188P1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organismal-level homeostasis#GO:0048871;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0032706|UniProtKB=B7YZX2 B7YZX2 Irk3 PTHR11767:SF102 INWARD RECTIFIER POTASSIUM CHANNEL INWARDLY RECTIFYING POTASSIUM CHANNEL 1, ISOFORM F-RELATED voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 DROME|FlyBase=FBgn0261550|UniProtKB=A0A0B4JCZ0 A0A0B4JCZ0 Orp8 PTHR10972:SF220 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0030731|UniProtKB=Q9VXJ0 Q9VXJ0 Mfe2 PTHR13078:SF56 PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0013576|UniProtKB=A0A0B4K620 A0A0B4K620 mtd PTHR23354:SF132 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED OXIDATION RESISTANCE PROTEIN 1 response to stress#GO:0006950;response to stimulus#GO:0050896;response to oxidative stress#GO:0006979 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0034379|UniProtKB=A1ZBC5 A1ZBC5 Dmel\CG15073 PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0038827|UniProtKB=Q8MYL1 Q8MYL1 Fancd2 PTHR32086:SF0 FANCONI ANEMIA GROUP D2 PROTEIN FANCONI ANEMIA GROUP D2 PROTEIN protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;cell communication#GO:0007154;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;meiotic chromosome segregation#GO:0045132;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;signaling#GO:0023052;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;response to stress#GO:0006950;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;homologous chromosome pairing at meiosis#GO:0007129;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;homologous recombination#GO:0035825;sexual reproduction#GO:0019953;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;nuclear chromosome segregation#GO:0098813;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793 DROME|FlyBase=FBgn0000482|UniProtKB=Q24314 Q24314 dor PTHR23323:SF29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endomembrane system organization#GO:0010256;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;organelle organization#GO:0006996;vesicle organization#GO:0016050;endosome organization#GO:0007032;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;lytic vacuole organization#GO:0080171;transport#GO:0006810;intracellular transport#GO:0046907;cellular component organization#GO:0016043;vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vesicle tethering complex#GO:0099023;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0086779|UniProtKB=Q0E8N2 Q0E8N2 step PTHR10663:SF402 GUANYL-NUCLEOTIDE EXCHANGE FACTOR MIP16918P cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0261648|UniProtKB=P39770 P39770 salm PTHR23233:SF84 SAL-LIKE PROTEIN FI23031P1-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0002576|UniProtKB=Q9W349 Q9W349 lz PTHR11950:SF31 RUNT RELATED PROTEIN LOZENGE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 DROME|FlyBase=FBgn0036897|UniProtKB=B7Z078 B7Z078 Rnf146 PTHR13417:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF146 E3 UBIQUITIN-PROTEIN LIGASE RNF146 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030676|UniProtKB=Q9VXR1 Q9VXR1 Dmel\CG12379 PTHR20922:SF13 DNL-TYPE ZINC FINGER PROTEIN DNL-TYPE ZINC FINGER PROTEIN intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular transport#GO:0046907;biosynthetic process#GO:0009058;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;localization#GO:0051179;protein metabolic process#GO:0019538;chaperone-mediated protein complex assembly#GO:0051131;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;mitochondrial transmembrane transport#GO:1990542;protein folding#GO:0006457;mitochondrial transport#GO:0006839;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0261239|UniProtKB=Q05192 Q05192 Hr39 PTHR24086:SF25 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NUCLEAR HORMONE RECEPTOR FTZ-F1 BETA C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0261286|UniProtKB=Q8IH00 Q8IH00 Mat89Ba PTHR17972:SF0 NUCLEOLAR RNA-ASSOCIATED PROTEIN NUCLEOLAR PROTEIN 6 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274 preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0027095|UniProtKB=Q9XZ63 Q9XZ63 Manf PTHR12990:SF5 ARMET-LIKE PROTEIN MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR HOMOLOG receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;cellular component organization#GO:0016043;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0262716|UniProtKB=P32392 P32392 Arp3 PTHR11937:SF31 ACTIN ACTIN-RELATED PROTEIN 3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;structural molecule activity#GO:0005198;cytoskeletal protein binding#GO:0008092 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807 DROME|FlyBase=FBgn0027655|UniProtKB=Q9V3N4 Q9V3N4 htt PTHR10170:SF11 HUNTINGTON DISEASE PROTEIN HUNTINGTIN, ISOFORM A organelle localization#GO:0051640;system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;developmental process#GO:0032502;transport#GO:0006810;regulation of response to stimulus#GO:0048583;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;vesicle cytoskeletal trafficking#GO:0099518;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle localization#GO:0051648;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;microtubule-based transport#GO:0099111;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle transport#GO:0048489;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;synaptic vesicle localization#GO:0097479 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0037305|UniProtKB=Q9VN95 Q9VN95 Enoph PTHR20371:SF1 ENOLASE-PHOSPHATASE E1 ENOLASE-PHOSPHATASE E1 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0032972|UniProtKB=Q9V9P1 Q9V9P1 Dmel\CG10834 PTHR10779:SF17 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 1 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037988|UniProtKB=Q95TZ4 Q95TZ4 Cs2 PTHR11739:SF8 CITRATE SYNTHASE CITRATE SYNTHASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 metabolite interconversion enzyme#PC00262;transferase#PC00220 Pyruvate metabolism#P02772>Citrate Synthetase#P03141;TCA cycle#P00051>Citrate Synthase#P01267 DROME|FlyBase=FBgn0034743|UniProtKB=Q9W237 Q9W237 RpS16 PTHR21569:SF16 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9 structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202 DROME|FlyBase=FBgn0038923|UniProtKB=Q8MS27 Q8MS27 mRpL35 PTHR15909:SF0 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ribosomal protein#PC00202 DROME|FlyBase=FBgn0085207|UniProtKB=A8DYV1 A8DYV1 Dmel\CG34178 PTHR39957:SF1 AT09846P1-RELATED AT09846P1-RELATED DROME|FlyBase=FBgn0285911|UniProtKB=Q9VHG1 Q9VHG1 Vps16A PTHR12811:SF3 VACUOLAR PROTEIN SORTING VPS16 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;vacuole fusion#GO:0097576;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;vacuole fusion, non-autophagic#GO:0042144;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0034517|UniProtKB=Q7K5J8 Q7K5J8 Cpr57A PTHR12236:SF7 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 57A, ISOFORM A extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0003654|UniProtKB=Q24246 Q24246 sw PTHR12442:SF22 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular localization#GO:0051641;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;microtubule-based transport#GO:0099111;transport#GO:0006810 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;organelle#GO:0043226;dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0050269|UniProtKB=Q9W217 Q9W217 Dmel\CG30269 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED transition metal ion binding#GO:0046914;ion binding#GO:0043167;zinc ion binding#GO:0008270;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035766|UniProtKB=Q9VS50 Q9VS50 eco PTHR45884:SF2 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ECO protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic sister chromatid cohesion#GO:0007064;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0250851|UniProtKB=A0A0B4KEY8 A0A0B4KEY8 BEST:GH01256 PTHR28672:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446 cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DROME|FlyBase=FBgn0053194|UniProtKB=Q8T0X8 Q8T0X8 CheA29a PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0261671|UniProtKB=X2JA38 X2JA38 tweek PTHR31640:SF1 TRANSMEMBRANE PROTEIN KIAA1109 BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 1 synaptic vesicle recycling#GO:0036465;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle endocytosis#GO:0048488;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;synaptic vesicle cycle#GO:0099504 DROME|FlyBase=FBgn0031589|UniProtKB=Q9VQX4 Q9VQX4 Naprt PTHR11098:SF1 NICOTINATE PHOSPHORIBOSYLTRANSFERASE NICOTINATE PHOSPHORIBOSYLTRANSFERASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0015396|UniProtKB=Q9XTP7 Q9XTP7 jumu PTHR13962:SF17 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0050486|UniProtKB=A1Z959 A1Z959 Dmel\CG30486 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0284257|UniProtKB=Q7K556 Q7K556 Ttd14 PTHR34932:SF2 TRPL TRANSLOCATION DEFECT PROTEIN 14 TRPL TRANSLOCATION DEFECT PROTEIN 14 lipid binding#GO:0008289;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091 homeostatic process#GO:0042592;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;retina homeostasis#GO:0001895;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249 DROME|FlyBase=FBgn0285910|UniProtKB=Q9W4P5 Q9W4P5 VhaAC39-1 PTHR11028:SF6 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of biological quality#GO:0065008;cellular localization#GO:0051641;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801 intracellular organelle#GO:0043229;endosome#GO:0005768;ATPase complex#GO:1904949;early endosome#GO:0005769;ATPase dependent transmembrane transport complex#GO:0098533;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;proton-transporting two-sector ATPase complex#GO:0016469;lytic vacuole#GO:0000323;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;vesicle#GO:0031982;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886 ATP synthase#PC00002 DROME|FlyBase=FBgn0030739|UniProtKB=Q9VXH9 Q9VXH9 SWIP PTHR31409:SF0 WASH COMPLEX SUBUNIT 4 WASH COMPLEX SUBUNIT 4 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 DROME|FlyBase=FBgn0031209|UniProtKB=Q9VPI2 Q9VPI2 Ir21a PTHR18966:SF413 IONOTROPIC GLUTAMATE RECEPTOR IONOTROPIC RECEPTOR 21A extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0039293|UniProtKB=Q9VBV8 Q9VBV8 Alg9 PTHR22760:SF2 GLYCOSYLTRANSFERASE ALPHA-1,2-MANNOSYLTRANSFERASE ALG9 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0032289|UniProtKB=M9MRT1 M9MRT1 chr2L_10724193_10724543.0 PTHR11610:SF36 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0034095|UniProtKB=Q7JR82 Q7JR82 Dmel\CG15701 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0051515|UniProtKB=Q9VCM5 Q9VCM5 Dmel\CG31515 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0086451|UniProtKB=Q9VM75 Q9VM75 Heatr1 PTHR13457:SF1 BAP28 HEAT REPEAT-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of transcription by RNA polymerase I#GO:0006356;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840 small-subunit processome#GO:0032040;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037461|UniProtKB=Q9VI39 Q9VI39 Dmel\CG15177 PTHR23055:SF190 CALCIUM BINDING PROTEINS AT17667P-RELATED calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 DROME|FlyBase=FBgn0035711|UniProtKB=Q9VRY2 Q9VRY2 Dmel\CG8519 PTHR45704:SF19 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE DROME|FlyBase=FBgn0263237|UniProtKB=Q24216 Q24216 Cdk7 PTHR24056:SF0 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 7 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;DNA-templated transcription initiation#GO:0006352;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;regulation of cell cycle#GO:0051726;DNA-templated transcription#GO:0006351 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transferase complex#GO:1990234 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0040346|UniProtKB=Q9V3R3 Q9V3R3 Dmel\CG3704 PTHR21231:SF8 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0250911|UniProtKB=B7Z0I5 B7Z0I5 Dmel\CG42245 PTHR31195:SF2 GEO02494P1 GEO02494P1 DROME|FlyBase=FBgn0035800|UniProtKB=Q9VS91 Q9VS91 t-Grip84 PTHR19302:SF13 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 2 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0000063|UniProtKB=A0A0B4KG66 A0A0B4KG66 Mps1 PTHR22974:SF21 MIXED LINEAGE PROTEIN KINASE DUAL SPECIFICITY PROTEIN KINASE TTK catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;cell communication#GO:0007154;sexual reproduction#GO:0019953;negative regulation of chromosome organization#GO:2001251;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of reproductive process#GO:2000241;regulation of mitotic cell cycle#GO:0007346;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;negative regulation of mitotic nuclear division#GO:0045839;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;negative regulation of cell cycle#GO:0045786;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;negative regulation of chromosome segregation#GO:0051985;meiotic cell cycle#GO:0051321;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046 condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;chromosome#GO:0005694;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036537|UniProtKB=Q9VUU7 Q9VUU7 Dmel\CG18081 PTHR21213:SF0 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 DROME|FlyBase=FBgn0261360|UniProtKB=A4V243 A4V243 Dmel\CG42637 PTHR11920:SF474 GUANYLYL CYCLASE GUANYLATE CYCLASE-RELATED lyase activity#GO:0016829;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383 cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 lyase#PC00144;guanylate cyclase#PC00114 DROME|FlyBase=FBgn0026086|UniProtKB=Q9NII1 Q9NII1 Adar PTHR10910:SF62 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN AT07585P-RELATED RNA binding#GO:0003723;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on RNA#GO:0140098;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;base conversion or substitution editing#GO:0016553;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;adenosine to inosine editing#GO:0006382;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034782|UniProtKB=Q9W1Z2 Q9W1Z2 Dmel\CG12490 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0033101|UniProtKB=Q7JVH6 Q7JVH6 Ar4 PTHR11732:SF385 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0035858|UniProtKB=Q9VSF9 Q9VSF9 Dmel\CG13674 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0037986|UniProtKB=Q9VGD7 Q9VGD7 Dmel\CG14736 PTHR10264:SF137 BAND 7 PROTEIN-RELATED GH04404P1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0034950|UniProtKB=Q95SH0 Q95SH0 Pask PTHR24346:SF51 MAP/MICROTUBULE AFFINITY-REGULATING KINASE PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 negative regulation of metabolic process#GO:0009892;regulation of carbohydrate biosynthetic process#GO:0043255;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of biosynthetic process#GO:0009890;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030332|UniProtKB=Q9VYU9 Q9VYU9 Dmel\CG9360 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0033540|UniProtKB=Q7K4B3 Q7K4B3 Elp2 PTHR44111:SF2 ELONGATOR COMPLEX PROTEIN 2 ELONGATOR COMPLEX PROTEIN 2 catalytic complex#GO:1902494;elongator holoenzyme complex#GO:0033588;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0033292|UniProtKB=Q9V4T3 Q9V4T3 Cyp4ad1 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 DROME|FlyBase=FBgn0044049|UniProtKB=Q9VT53 Q9VT53 Ilp4 PTHR10423:SF3 INSULIN-LIKE 3 INSULIN-LIKE 3 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;signaling#GO:0023052;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of reproductive process#GO:2000241;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0034563|UniProtKB=Q4V664 Q4V664 Dmel\CG15649 PTHR39951:SF2 FI22632P1 IP05660P DROME|FlyBase=FBgn0035887|UniProtKB=Q9VSJ2 Q9VSJ2 Jon66Cii PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0036235|UniProtKB=M9PI24 M9PI24 Dmel\CG6938 PTHR12308:SF91 ANOCTAMIN ANOCTAMIN molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0033982|UniProtKB=Q9V776 Q9V776 Cyp317a1 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0038290|UniProtKB=Q9VFD1 Q9VFD1 anon-WO0140519.208 PTHR22917:SF6 HEMOPEXIN DOMAIN-CONTAINING PROTEIN EG:8D8.2 PROTEIN-RELATED DROME|FlyBase=FBgn0036337|UniProtKB=Q9VU38 Q9VU38 Adk2 PTHR45769:SF3 ADENOSINE KINASE ADENOSINE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773 purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0263395|UniProtKB=A1ZBH7 A1ZBH7 hppy PTHR48012:SF18 STERILE20-LIKE KINASE, ISOFORM B-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>GCKR#P00311;Apoptosis signaling pathway#P00006>GCK#P00268 DROME|FlyBase=FBgn0036158|UniProtKB=Q9VTI1 Q9VTI1 Dmel\CG6149 PTHR10989:SF16 ANDROGEN-INDUCED PROTEIN 1-RELATED AT02829P-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 DROME|FlyBase=FBgn0034925|UniProtKB=Q9W1H1 Q9W1H1 Mettl9 PTHR12890:SF0 DREV PROTEIN PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0040752|UniProtKB=A1Z9K8 A1Z9K8 Prosap PTHR24135:SF30 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN LD13733P signaling adaptor activity#GO:0035591;protein binding#GO:0005515;signaling receptor complex adaptor activity#GO:0030159;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 postsynaptic membrane#GO:0045211;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197;cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 scaffold/adaptor protein#PC00226 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 DROME|FlyBase=FBgn0040370|UniProtKB=Q9W5G7 Q9W5G7 EG:BACR37P7.8 PTHR24070:SF290 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE, FAMILY 10, MEMBER A hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 DROME|FlyBase=FBgn0017577|UniProtKB=Q9VGW6 Q9VGW6 Mcm5 PTHR11630:SF42 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM5 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA replication initiation#GO:0006270;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 DROME|FlyBase=FBgn0028434|UniProtKB=Q7KMG7 Q7KMG7 Ercc1 PTHR12749:SF0 EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1 DNA EXCISION REPAIR PROTEIN ERCC-1 DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular response to abiotic stimulus#GO:0071214;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;response to UV#GO:0009411;DNA damage response#GO:0006974;DNA recombination#GO:0006310 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 endodeoxyribonuclease#PC00093 DROME|FlyBase=FBgn0259677|UniProtKB=Q0KHN6 Q0KHN6 CG40500 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0053159|UniProtKB=Q9VZT0 Q9VZT0 CG11532 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036937|UniProtKB=Q9VW78 Q9VW78 Ir76b PTHR18966:SF399 IONOTROPIC GLUTAMATE RECEPTOR IONOTROPIC RECEPTOR CORECEPTOR IR76B transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;cellular process#GO:0009987 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0066303|UniProtKB=Q8SXX5 Q8SXX5 CG32530-ORFB PTHR13568:SF9 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 203 cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0038247|UniProtKB=Q9VFH5 Q9VFH5 Cad88C PTHR24028:SF263 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 1 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 DROME|Gene_ORFName=Dmel_CG46518|UniProtKB=A0ACD4DAU5 A0ACD4DAU5 CG46518 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0033615|UniProtKB=A1Z8J0 A1Z8J0 CG7741 PTHR12072:SF4 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634 DROME|FlyBase=FBgn0289323|UniProtKB=A1ZAK1 A1ZAK1 IntS8 PTHR13350:SF1 INTEGRATOR COMPLEX SUBUNIT 8 INTEGRATOR COMPLEX SUBUNIT 8 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;integrator complex#GO:0032039;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0030747|UniProtKB=Q9VXG6 Q9VXG6 Dmel\CG4301 PTHR24092:SF230 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE intramembrane lipid carrier activity#GO:0140303;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;lipid transport#GO:0006869 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0032222|UniProtKB=Q9VKZ1 Q9VKZ1 Cox10 PTHR43448:SF2 PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982 DROME|FlyBase=FBgn0031824|UniProtKB=Q9VMC6 Q9VMC6 152078_at PTHR42807:SF1 GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 DROME|FlyBase=FBgn0031296|UniProtKB=Q9VPV7 Q9VPV7 gNacalpha PTHR21713:SF4 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED GH09281P-RELATED protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0033807|UniProtKB=Q7KY01 Q7KY01 AQP PTHR21191:SF16 AQUAPORIN AQUAPORIN water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of cellular component size#GO:0032535;cellular process#GO:0009987;cellular component organization#GO:0016043;intracellular chemical homeostasis#GO:0055082;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0024807|UniProtKB=Q9TW27 Q9TW27 DIP1 PTHR46205:SF5 LOQUACIOUS, ISOFORM B BLANKS-RELATED RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of gene silencing by regulatory ncRNA#GO:0060966;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 DROME|FlyBase=FBgn0039555|UniProtKB=Q9VAY9 Q9VAY9 mRpS22 PTHR13071:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22 SMALL RIBOSOMAL SUBUNIT PROTEIN MS22 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 DROME|FlyBase=FBgn0035582|UniProtKB=Q8SX23 Q8SX23 CG13705-PA PTHR36135:SF2 FIBROUS SHEATH CABYR-BINDING PROTEIN FIBROUS SHEATH CABYR-BINDING PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 DROME|FlyBase=FBgn0260642|UniProtKB=P02833 P02833 Antp PTHR45659:SF24 HOMEOBOX PROTEIN HOX HOMEOTIC PROTEIN ANTENNAPEDIA-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0039492|UniProtKB=Q9VB70 Q9VB70 CG6051 PTHR46465:SF2 LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 DROME|FlyBase=FBgn0015789|UniProtKB=O15971 O15971 Rab10 PTHR47980:SF23 LD44762P SMALL MONOMERIC GTPASE export from cell#GO:0140352;endocytic recycling#GO:0032456;localization within membrane#GO:0051668;secretion by cell#GO:0032940;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;endosomal transport#GO:0016197;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;secretory vesicle#GO:0099503;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;TGF-beta signaling pathway#P00052>Ras-GDP#P01291 DROME|FlyBase=FBgn0030365|UniProtKB=Q9VYQ9 Q9VYQ9 Tango4 PTHR19923:SF0 WD40 REPEAT PROTEINPRL1/PRL2-RELATED PLEIOTROPIC REGULATOR 1 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0040726|UniProtKB=A1ZBY3 A1ZBY3 dpr1 PTHR23279:SF7 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 1, ISOFORM A cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043 cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252 DROME|FlyBase=FBgn0036463|UniProtKB=Q9VUJ2 Q9VUJ2 Reck PTHR13487:SF4 SERINE PROTEASE INHIBITOR FI21605P1 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0033138|UniProtKB=A1Z6U8 A1Z6U8 Tsp42Eq PTHR19282:SF456 TETRASPANIN FI23944P1-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0053690|UniProtKB=Q4ABJ0 Q4ABJ0 dls PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0052413|UniProtKB=Q8I936 Q8I936 CG10487 PTHR12283:SF5 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;zinc ion binding#GO:0008270;transferase activity#GO:0016740;catalytic activity#GO:0003824;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;acyltransferase activity#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 transferase#PC00220 DROME|FlyBase=FBgn0003415|UniProtKB=Q7KTX8 Q7KTX8 skd PTHR48249:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DROME|FlyBase=FBgn0027945|UniProtKB=Q9U616 Q9U616 ppl PTHR11715:SF3 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0034704|UniProtKB=Q9W281 Q9W281 Fbxo42 PTHR46432:SF1 F-BOX ONLY PROTEIN 42 F-BOX ONLY PROTEIN 42 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005 DROME|FlyBase=FBgn0030717|UniProtKB=Q9VXK8 Q9VXK8 Slc25A46a PTHR21252:SF3 TB1 PROTEIN-RELATED FI08023P-RELATED mitochondrion organization#GO:0007005;organelle fission#GO:0048285;mitochondrial fission#GO:0000266;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 DROME|FlyBase=FBgn0032020|UniProtKB=Q9VLP3 Q9VLP3 strat PTHR13276:SF0 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892 membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0029975|UniProtKB=Q9W3N1 Q9W3N1 spidey PTHR43899:SF49 RH59310P RH59310P catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0029762|UniProtKB=Q9W4C5 Q9W4C5 NAAT1 PTHR11616:SF334 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1 carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;establishment of localization#GO:0051234;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 DROME|FlyBase=FBgn0053977|UniProtKB=Q2PDR0 Q2PDR0 Dpm3 PTHR16433:SF0 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;mannosyltransferase complex#GO:0031501;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494 transferase#PC00220 DROME|FlyBase=FBgn0261436|UniProtKB=Q9VMY9 Q9VMY9 DhpD PTHR11271:SF6 GUANINE DEAMINASE GUANINE DEAMINASE transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 deaminase#PC00088 Purine metabolism#P02769>Guanine Deaminase#P03118;Xanthine and guanine salvage pathway#P02788>Guanine deaminase#P03249 DROME|FlyBase=FBgn0010415|UniProtKB=P49415 P49415 Sdc PTHR10915:SF1 SYNDECAN SYNDECAN cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0050345|UniProtKB=Q1EC10 Q1EC10 Dmel\CG30345 PTHR23507:SF39 ZGC:174356 GH23453P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0039081|UniProtKB=A0A0B4LHI9 A0A0B4LHI9 Irk2 PTHR11767:SF113 INWARD RECTIFIER POTASSIUM CHANNEL INWARDLY RECTIFYING POTASSIUM CHANNEL 2, ISOFORM D transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 DROME|FlyBase=FBgn0032511|UniProtKB=Q9VJZ4 Q9VJZ4 ND-B22 PTHR12868:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0030240|UniProtKB=Q9VZ63 Q9VZ63 Dmel\CG2202 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0015024|UniProtKB=P54367 P54367 CkIalpha PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 DROME|FlyBase=FBgn0036606|UniProtKB=Q9VV30 Q9VV30 BcDNA:RE40431 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0027560|UniProtKB=Q9Y119 Q9Y119 Tps1 PTHR10788:SF133 TREHALOSE-6-PHOSPHATE SYNTHASE BCDNA.GH08860 sugar-phosphatase activity#GO:0050308;glucosyltransferase activity#GO:0046527;hydrolase activity#GO:0016787;UDP-glucosyltransferase activity#GO:0035251;phosphatase activity#GO:0016791;hexosyltransferase activity#GO:0016758;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;phosphoric ester hydrolase activity#GO:0042578 metabolic process#GO:0008152;oligosaccharide biosynthetic process#GO:0009312;oligosaccharide metabolic process#GO:0009311;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058 DROME|FlyBase=FBgn0039104|UniProtKB=Q9VCJ6 Q9VCJ6 bs30h03.y1 PTHR21580:SF61 SHIPPO-1-RELATED AT18965P cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 structural protein#PC00211 DROME|FlyBase=FBgn0266917|UniProtKB=Q9VEP9 Q9VEP9 Sf3a1 PTHR15316:SF1 SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED SPLICING FACTOR 3A SUBUNIT 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0015371|UniProtKB=Q7YU81 Q7YU81 chn PTHR24392:SF62 ZINC FINGER PROTEIN PROTEIN CHARLATAN-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0030081|UniProtKB=Q9W397 Q9W397 Dmel\CG7246 PTHR23271:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511;binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139 ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0021761|UniProtKB=Q9V463 Q9V463 Nup154 PTHR10350:SF6 NUCLEAR PORE COMPLEX PROTEIN NUP155 NUCLEAR PORE COMPLEX PROTEIN NUP155 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;RNA localization#GO:0006403;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;localization within membrane#GO:0051668;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;protein import into nucleus#GO:0006606;protein transport#GO:0015031 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 DROME|FlyBase=FBgn0000308|UniProtKB=P25843 P25843 chic PTHR11604:SF0 PROFILIN PROFILIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin monomer binding#GO:0003785;binding#GO:0005488 cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 DROME|FlyBase=FBgn0002036|UniProtKB=P18487 P18487 anon-37Cs PTHR10742:SF398 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidase#PC00175 DROME|FlyBase=FBgn0010356|UniProtKB=P49846 P49846 Taf5 PTHR19879:SF12 TRANSCRIPTION INITIATION FACTOR TFIID CANNONBALL-RELATED protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;peptidase complex#GO:1905368;transferase complex#GO:1990234;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0000459|UniProtKB=P23792 P23792 disco PTHR15021:SF0 DISCONNECTED-RELATED DISCO-RELATED, ISOFORM A-RELATED regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0026533|UniProtKB=Q8T0D3 Q8T0D3 Dek PTHR13468:SF1 DEK PROTEIN PROTEIN DEK protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular component organization#GO:0016043;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0052208|UniProtKB=Q8IQU7 Q8IQU7 825-Oak PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0053208|UniProtKB=Q86BA1 Q86BA1 Mical PTHR23167:SF54 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL binding#GO:0005488;actin binding#GO:0003779;protein binding#GO:0005515;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;cytoskeletal protein binding#GO:0008092;oxidoreductase activity#GO:0016491 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;protein-containing complex organization#GO:0043933;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031651|UniProtKB=Q9VMY1 Q9VMY1 mRpL24 PTHR12903:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN UL24M metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 ribosomal protein#PC00202 DROME|FlyBase=FBgn0290109|UniProtKB=P41374 P41374 eIF2alpha PTHR10602:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 protein-containing complex binding#GO:0044877;translation initiation factor activity#GO:0003743;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;translation factor activity#GO:0180051;binding#GO:0005488 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 translation factor#PC00223;translation initiation factor#PC00224 Apoptosis signaling pathway#P00006>ELF2alpha#P00307 DROME|FlyBase=FBgn0052581|UniProtKB=Q8IR26 Q8IR26 sordd2 PTHR12313:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0050075|UniProtKB=A1Z9Q7 A1Z9Q7 Dmel\CG30075 PTHR46674:SF1 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 protein binding#GO:0005515;binding#GO:0005488;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879 male gamete generation#GO:0048232;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0037368|UniProtKB=Q9VNH1 Q9VNH1 Amus PTHR12315:SF0 BICOID-INTERACTING PROTEIN RELATED 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;snRNA binding#GO:0017069;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 DROME|FlyBase=FBgn0027620|UniProtKB=Q9V9T4 Q9V9T4 Acf PTHR46510:SF1 BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA replication#GO:0045740;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;positive regulation of DNA metabolic process#GO:0051054;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of chromatin organization#GO:1902275;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;regulation of DNA replication#GO:0006275;regulation of DNA-templated transcription#GO:0006355 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603 DROME|FlyBase=FBgn0032259|UniProtKB=Q9VKU5 Q9VKU5 Dmel\CG6144 PTHR46030:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6 RNA_DNA DEMETHYLASE ALKBH6-RELATED dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0051028|UniProtKB=Q9VA99 Q9VA99 Rsod PTHR20910:SF1 AGAP001623-PA RELATED TO SOD DROME|FlyBase=FBgn0038257|UniProtKB=H8F4T3 H8F4T3 smp-30 PTHR10907:SF66 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;esterase#PC00097 DROME|FlyBase=FBgn0035839|UniProtKB=Q9VSD8 Q9VSD8 Dmel\CG7550 PTHR22966:SF76 2-AMINOETHANETHIOL DIOXYGENASE 2-AMINOETHANETHIOL DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 response to hypoxia#GO:0001666;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to abiotic stimulus#GO:0009628;cellular response to hypoxia#GO:0071456;response to stress#GO:0006950;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031409|UniProtKB=Q9VQA4 Q9VQA4 Dmel\CG4271 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032551|UniProtKB=Q7KT84 Q7KT84 Dmel\CG18636 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0026316|UniProtKB=Q7K738 Q7K738 Ubc10 PTHR24068:SF116 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>UbcH8#P01223;Parkinson disease#P00049>UbcH7#P01224 DROME|FlyBase=FBgn0042131|UniProtKB=Q9I7T1 Q9I7T1 Dmel\CG18808 PTHR11091:SF0 OXIDOREDUCTASE-RELATED MALATE DEHYDROGENASE oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Allantoin degradation#P02725>Ureidoglycolate dehydrogenase#P02820;TCA cycle#P00051>Malate Dehydrogenase#P01270;Pyruvate metabolism#P02772>Malate Dehydrogenase#P03138 DROME|FlyBase=FBgn0259170|UniProtKB=P53624 P53624 alpha-Man-Ia PTHR11742:SF6 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033706|UniProtKB=A1Z8V7 A1Z8V7 Vha36-2 PTHR11671:SF5 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 vacuolar acidification#GO:0007035;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453;homeostatic process#GO:0042592;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;vacuolar membrane#GO:0005774 ATP synthase#PC00002 DROME|FlyBase=FBgn0031907|UniProtKB=C9QPE7 C9QPE7 Tpp PTHR43768:SF3 TREHALOSE 6-PHOSPHATE PHOSPHATASE TREHALOSE 6-PHOSPHATE PHOSPHATASE phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0025781|UniProtKB=Q9VCN6 Q9VCN6 Cdc16 PTHR12558:SF9 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 16 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;protein modification by small protein conjugation or removal#GO:0070647;anaphase-promoting complex-dependent catabolic process#GO:0031145;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;positive regulation of cell cycle process#GO:0090068;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;positive regulation of cell cycle#GO:0045787;proteasomal protein catabolic process#GO:0010498;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cell division#GO:0051301;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346 intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0032585|UniProtKB=Q9VJK5 Q9VJK5 Nepl8 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0019932|UniProtKB=P91931 P91931 SamDC PTHR11570:SF0 S-ADENOSYLMETHIONINE DECARBOXYLASE S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME metabolite interconversion enzyme#PC00262;lyase#PC00144;decarboxylase#PC00089 DROME|FlyBase=FBgn0039101|UniProtKB=Q9VCJ9 Q9VCJ9 Dmel\CG16710 PTHR24260:SF144 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED Toll pathway-drosophila#P06217>SPE#P06340 DROME|FlyBase=FBgn0036353|UniProtKB=Q8IQJ7 Q8IQJ7 Dmel\CG10171 PTHR13353:SF5 TRANSMEMBRANE PROTEIN 19 TRANSMEMBRANE PROTEIN 19 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0032775|UniProtKB=Q9VIX4 Q9VIX4 Dmel\CG17544 PTHR10909:SF223 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE organic acid binding#GO:0043177;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;lipid binding#GO:0008289;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;fatty acid binding#GO:0005504;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0004177|UniProtKB=P23696 P23696 mts PTHR45619:SF12 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PP2A phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway feedback loops 2#P04398>PP2A-C#P04659;Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;p53 pathway#P00059>PP2A#P04630;EGF receptor signaling pathway#P00018>PP2A#P00547;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643 DROME|FlyBase=FBgn0000339|UniProtKB=P49858 P49858 cni PTHR12290:SF48 CORNICHON-RELATED PROTEIN CORNICHON intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0264607|UniProtKB=Q00168 Q00168 CaMKII PTHR24347:SF458 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 DROME|FlyBase=FBgn0287720|UniProtKB=P52295 P52295 Pen PTHR23316:SF71 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to organelle#GO:0033365;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0026388|UniProtKB=Q9V3N2 Q9V3N2 Or46a PTHR21137:SF37 ODORANT RECEPTOR ODORANT RECEPTOR 46A, ISOFORM B-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0052214|UniProtKB=Q8IQU8 Q8IQU8 Dmel\CG32214 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0015558|UniProtKB=Q9U6L4 Q9U6L4 tty PTHR12424:SF20 TWEETY-RELATED PROTEIN TWEETY ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0031758|UniProtKB=Q9VMK0 Q9VMK0 Ucp4B PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;response to cold#GO:0009409;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0028467|UniProtKB=Q9U4F8 Q9U4F8 Ube4A PTHR13931:SF16 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 A catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0038437|UniProtKB=Q8SZ16 Q8SZ16 Sdhaf3 PTHR13137:SF6 DC11 ACN9 HOMOLOG SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL cellular component assembly#GO:0022607;mitochondrial respiratory chain complex II assembly#GO:0034553;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0011361|UniProtKB=Q94519 Q94519 ND-ACP PTHR20863:SF80 ACYL CARRIER PROTEIN ACYL CARRIER PROTEIN, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;molecular carrier activity#GO:0140104 membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0036734|UniProtKB=Q9VVI1 Q9VVI1 Alsin2 PTHR12375:SF30 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN ALSIN2-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685 DROME|FlyBase=FBgn0034106|UniProtKB=A1ZAD3 A1ZAD3 Dmel\CG9068 PTHR46532:SF4 MALE FERTILITY FACTOR KL5 DYNEIN HEAVY CHAIN, CYTOPLASMIC Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0014879|UniProtKB=P53997 P53997 Set PTHR11875:SF49 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0033697|UniProtKB=Q9V676 Q9V676 Cyp6t3 PTHR24292:SF45 CYTOCHROME P450 CYTOCHROME P450 6G1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0031722|UniProtKB=Q9VMP2 Q9VMP2 Dmel\CG14011 PTHR23247:SF2 NY-REN-41 ANTIGEN L15 -RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 34 DROME|FlyBase=FBgn0039642|UniProtKB=Q9VAN8 Q9VAN8 Dmel\CG11882 PTHR14787:SF1 C10ORF188 FAMILY MEMBER ATPASE PAAT ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0035217|UniProtKB=Q9W0F6 Q9W0F6 FucTD PTHR48438:SF3 ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED FUCOSYLTRANSFERASE DROME|FlyBase=FBgn0035688|UniProtKB=M9PEH8 M9PEH8 fmt PTHR12634:SF40 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED FIERY MOUNTAIN, ISOFORM D protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 phosphatase modulator#PC00184 DROME|FlyBase=FBgn0053276|UniProtKB=Q7KU86 Q7KU86 Urm1 PTHR14986:SF4 RURM1 PROTEIN UBIQUITIN-RELATED MODIFIER 1 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036290|UniProtKB=Q9VTY2 Q9VTY2 Ar2 PTHR11732:SF385 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0036527|UniProtKB=Q8IA44 Q8IA44 pgant12 PTHR11675:SF134 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0033087|UniProtKB=A1Z6M8 A1Z6M8 Hsepi PTHR13174:SF3 D-GLUCURONYL C5-EPIMERASE D-GLUCURONYL C5-EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857 proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 isomerase#PC00135 DROME|FlyBase=FBgn0031728|UniProtKB=Q9VMN5 Q9VMN5 Hsp60C PTHR45633:SF53 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN HOMOLOG 1, MITOCHONDRIAL-RELATED protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 protein metabolic process#GO:0019538;localization#GO:0051179;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular localization#GO:0051641;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;apoptotic process#GO:0006915;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;response to stress#GO:0006950;organelle organization#GO:0006996 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0013720|UniProtKB=O76899 O76899 pck PTHR21284:SF13 EG:80H7.2 PROTEIN EG:80H7.2 PROTEIN animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607 tight junction#GO:0070160;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;apical junction complex#GO:0043296 DROME|FlyBase=FBgn0027279|UniProtKB=Q9VR59 Q9VR59 l(1)G0196 PTHR12750:SF25 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 kinase#PC00137;nucleotide kinase#PC00172 DROME|FlyBase=FBgn0034219|UniProtKB=Q9V817 Q9V817 mthl4 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036889|UniProtKB=Q9VW14 Q9VW14 CG14100 PTHR43191:SF2 RRNA METHYLTRANSFERASE 3, RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0037678|UniProtKB=Q9VHF7 Q9VHF7 Dmel\CG16749 PTHR24276:SF100 POLYSERASE-RELATED FI18310P1-RELATED catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031064|UniProtKB=Q9VWD3 Q9VWD3 Dmel\CG12531 PTHR43243:SF17 INNER MEMBRANE TRANSPORTER YGJI-RELATED SOLUTE CARRIER FAMILY 7 MEMBER 14 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0262647|UniProtKB=Q9VKJ3 Q9VKJ3 Nup160 PTHR21286:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP160 NUCLEAR PORE COMPLEX PROTEIN NUP160 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 metabolic process#GO:0008152;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;response to heat#GO:0009408;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular response to heat#GO:0034605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;response to chemical#GO:0042221;chromosome localization#GO:0050000;response to temperature stimulus#GO:0009266;protein export from nucleus#GO:0006611;ribosome biogenesis#GO:0042254;telomere tethering at nuclear periphery#GO:0034398;cellular response to stress#GO:0033554;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;protein transport#GO:0015031;protein import into nucleus#GO:0006606;response to abiotic stimulus#GO:0009628;cellular component organization#GO:0016043;ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;response to stimulus#GO:0050896;ribonucleoprotein complex biogenesis#GO:0022613;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;biosynthetic process#GO:0009058;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;response to nitrogen compound#GO:1901698;telomere localization#GO:0034397;cellular response to stimulus#GO:0051716;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0015298|UniProtKB=P49963 P49963 Srp19 PTHR17453:SF0 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting#GO:0006605;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein-containing complex organization#GO:0043933;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;cellular component assembly#GO:0022607;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0259483|UniProtKB=Q7K0E3 Q7K0E3 Mob4 PTHR22599:SF1 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB-LIKE PROTEIN PHOCEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase activator#PC00138 DROME|FlyBase=FBgn0260775|UniProtKB=P92029 P92029 DnaJ-60 PTHR44825:SF1 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY C MEMBER 4 DROME|FlyBase=FBgn0029088|UniProtKB=Q9VNJ5 Q9VNJ5 disp PTHR45951:SF3 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0013810|UniProtKB=A0A6H2EJG3 A0A6H2EJG3 Dhc36C PTHR10676:SF310 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 7 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;microtubule motor activity#GO:0003777;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657 spermatid development#GO:0007286;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;cilium or flagellum-dependent cell motility#GO:0001539;inner dynein arm assembly#GO:0036159;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 microtubule cytoskeleton#GO:0015630;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;inner dynein arm#GO:0036156;membraneless organelle#GO:0043228;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;catalytic complex#GO:1902494;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0013303|UniProtKB=P42325 P42325 Nca PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 DROME|FlyBase=FBgn0014931|UniProtKB=Q8T053 Q8T053 kipf PTHR24377:SF995 IP01015P-RELATED LD25464P-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0052487|UniProtKB=Q9VZW4 Q9VZW4 CG2077 PTHR19288:SF93 4-NITROPHENYLPHOSPHATASE-RELATED FI11325P-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0030060|UniProtKB=Q9W3C3 Q9W3C3 Dmel\CG2004 PTHR11012:SF57 PROTEIN KINASE-LIKE DOMAIN-CONTAINING LD10016P DROME|FlyBase=FBgn0030494|UniProtKB=Q9VYC1 Q9VYC1 Cpr12A PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0037322|UniProtKB=Q9VNB3 Q9VNB3 Or83a PTHR21137:SF42 ODORANT RECEPTOR ODORANT RECEPTOR 83A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037462|UniProtKB=Q9VI40 Q9VI40 sunz PTHR23055:SF190 CALCIUM BINDING PROTEINS AT17667P-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 calmodulin-related#PC00061 DROME|FlyBase=FBgn0032209|UniProtKB=Q9VL05 Q9VL05 Hand PTHR23349:SF68 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FI14601P DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0030841|UniProtKB=Q9VX49 Q9VX49 Dmel\CG8568 PTHR36299:SF4 AGAP008005-PA GH07892P-RELATED DROME|FlyBase=FBgn0037374|UniProtKB=Q7K1V5 Q7K1V5 jagn PTHR20955:SF1 PROTEIN JAGUNAL HOMOLOG 1 PROTEIN JAGUNAL establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 DROME|FlyBase=FBgn0029123|UniProtKB=M9PCZ7 M9PCZ7 SoxN PTHR10270:SF324 SOX TRANSCRIPTION FACTOR SOXNEURO, ISOFORM B DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;negative regulation of metabolic process#GO:0009892;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 DROME|FlyBase=FBgn0033504|UniProtKB=A0A6M3QH40 A0A6M3QH40 CAP PTHR14167:SF125 SH3 DOMAIN-CONTAINING CAP, ISOFORM AC molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0026582|UniProtKB=Q9W2K8 Q9W2K8 Hmg-2 PTHR46040:SF3 HIGH MOBILITY GROUP PROTEIN 2 HIGH MOBILITY GROUP PROTEIN 2 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038584|UniProtKB=Q9VEB4 Q9VEB4 mTerf5 PTHR15437:SF7 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 5, MITOCHONDRIAL nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 nucleic acid biosynthetic process#GO:0141187;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;DNA-templated transcription termination#GO:0006353;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mitochondrial transcription#GO:0006390;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0039109|UniProtKB=Q9VCI9 Q9VCI9 Dmel\CG10365 PTHR12192:SF26 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1 catalytic activity#GO:0003824;lyase activity#GO:0016829 catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0025612|UniProtKB=Q9W4I5 Q9W4I5 CG3062 PTHR34639:SF1 PROTEIN FLATTOP PROTEIN FLATTOP cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929 DROME|FlyBase=FBgn0035604|UniProtKB=Q9VRL4 Q9VRL4 Ir64a PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536 postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cell junction#GO:0030054 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 DROME|FlyBase=FBgn0037717|UniProtKB=Q9VHA9 Q9VHA9 Dmel\CG8301 PTHR24377:SF995 IP01015P-RELATED LD25464P-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0039769|UniProtKB=Q9VA77 Q9VA77 Dmel\CG15534 PTHR10340:SF29 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;ceramide metabolic process#GO:0006672;organophosphate catabolic process#GO:0046434;cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingomyelin metabolic process#GO:0006684;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 hydrolase#PC00121;phosphodiesterase#PC00185 DROME|FlyBase=FBgn0033232|UniProtKB=A1Z765 A1Z765 Dmel\CG12159 PTHR28607:SF4 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174-LIKE DROME|FlyBase=FBgn0002629|UniProtKB=P13095 P13095 E(spl)m4-BFM PTHR12254:SF0 ENHANCER OF SPLIT MALPHA PROTEIN BARBU-RELATED DROME|FlyBase=FBgn0040754|UniProtKB=Q7JVR7 Q7JVR7 CG17059 PTHR28562:SF1 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 DROME|FlyBase=FBgn0033735|UniProtKB=Q7K209 Q7K209 Dera PTHR10889:SF3 DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOXYRIBOSE-PHOSPHATE ALDOLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829 nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleobase-containing compound metabolic process#GO:0006139;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleoside catabolic process#GO:0009164;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 lyase#PC00144;aldolase#PC00044 DROME|FlyBase=FBgn0032771|UniProtKB=Q9VIX9 Q9VIX9 Dmel\CG17349 PTHR21207:SF2 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED GH16267P-RELATED Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 DROME|FlyBase=FBgn0002174|UniProtKB=Q27237 Q27237 l(2)tid PTHR44145:SF5 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG L(2)TID, MITOCHONDRIAL cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 chaperone#PC00072 DROME|FlyBase=FBgn0003205|UniProtKB=P08646 P08646 Ras85D PTHR24070:SF468 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE PROTEIN 1 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;epidermal growth factor receptor signaling pathway#GO:0007173;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Ras Pathway#P04393>Ras#P04547;Integrin signalling pathway#P00034>Ras#P00916;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;PI3 kinase pathway#P00048>Ras#P01182;Angiogenesis#P00005>Ras#P00238;p53 pathway feedback loops 2#P04398>Ras#P04651;FGF signaling pathway#P00021>Ras#P00633 DROME|FlyBase=FBgn0033654|UniProtKB=Q95TY2 Q95TY2 Sobp PTHR23186:SF4 RETINOIC ACID-INDUCED PROTEIN 2 GH22790P animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0085305|UniProtKB=Q9VF11 Q9VF11 CG5470 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0011276|UniProtKB=Q9W4X2 Q9W4X2 HLH3B PTHR13864:SF15 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 HOMOLOG-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0043791|UniProtKB=Q9VHD0 Q9VHD0 phu PTHR11596:SF96 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0030508|UniProtKB=M9PHR3 M9PHR3 Dmel\CG15760 PTHR14971:SF2 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN BINDING PROTEIN VOPP1 molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035227|UniProtKB=Q9W0E3 Q9W0E3 Iml1 PTHR13179:SF8 DEP DOMAIN CONTAINING PROTEIN 5 GATOR1 COMPLEX PROTEIN DEPDC5 cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;negative regulation of TORC1 signaling#GO:1904262;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Seh1-associated complex#GO:0035859;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0037084|UniProtKB=Q7JY00 Q7JY00 Syx6 PTHR19957:SF435 SYNTAXIN HL02043P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;vesicle fusion#GO:0006906;cytosolic transport#GO:0016482;cellular component organization#GO:0016043 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 SNARE protein#PC00034 DROME|FlyBase=FBgn0263934|UniProtKB=Q9U1I1 Q9U1I1 esn PTHR24211:SF20 LIM DOMAIN-CONTAINING PROTEIN PROTEIN ESPINAS-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039830|UniProtKB=Q6NN09 Q6NN09 ATPsynC PTHR10031:SF0 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATPASE PROTEIN 9 ATP synthase#PC00002;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0035690|UniProtKB=A8JNL9 A8JNL9 Dmel\CG10274 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0031417|UniProtKB=M9PE54 M9PE54 BVRA PTHR22604:SF105 OXIDOREDUCTASES TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0040255|UniProtKB=Q9VGT1 Q9VGT1 Ugt35E2 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 DROME|FlyBase=FBgn0004237|UniProtKB=P48810 P48810 Hrb87F PTHR48027:SF18 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0033286|UniProtKB=Q8T8W0 Q8T8W0 Dmel\CG2127 PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0026634|UniProtKB=Q9VF78 Q9VF78 Cog2 PTHR12961:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2 establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;Golgi organization#GO:0007030 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;COG complex#GO:0017119;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0027600|UniProtKB=Q9Y156 Q9Y156 obst-B PTHR23301:SF104 CHITIN BINDING PERITROPHIN-A BCDNA.GH02976 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037229|UniProtKB=A8JQS3 A8JQS3 flip PTHR24124:SF14 ANKYRIN REPEAT FAMILY A FLIPPY protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0036783|UniProtKB=Q9VVP3 Q9VVP3 CheA75a PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0051789|UniProtKB=Q8INX6 Q8INX6 Dmel\CG31789 PTHR37685:SF1 GEO11136P1-RELATED GEO11136P1-RELATED DROME|FlyBase=FBgn0036970|UniProtKB=Q9VPH9 Q9VPH9 Spn77Bc PTHR11461:SF367 SERINE PROTEASE INHIBITOR, SERPIN GH21475P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0003882|UniProtKB=P22812 P22812 tub PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;signaling#GO:0023052;biological regulation#GO:0065007;cell cycle#GO:0007049;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0053548|UniProtKB=O46040 O46040 SmydA-8 PTHR46455:SF3 SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 9, ISOFORM A-RELATED intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038808|UniProtKB=Q9VDL0 Q9VDL0 Srp14 PTHR12013:SF0 SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN protein targeting#GO:0006605;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;localization within membrane#GO:0051668;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;SRP-dependent cotranslational protein targeting to membrane#GO:0006614 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031936|UniProtKB=Q9VLY4 Q9VLY4 Dmel\CG13794 PTHR11616:SF337 SODIUM/CHLORIDE DEPENDENT TRANSPORTER BLOATED TUBULES, ISOFORM B-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;glycine transmembrane transporter activity#GO:0015187;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;glycine transport#GO:0015816;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 DROME|FlyBase=FBgn0035248|UniProtKB=Q9W0B7 Q9W0B7 Dmel\CG13919 PTHR13568:SF4 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 60 DROME|FlyBase=FBgn0032018|UniProtKB=Q9VLP5 Q9VLP5 Dmel\CG7806 PTHR24223:SF330 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 10 xenobiotic transmembrane transporter activity#GO:0042910;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0020493|UniProtKB=A0A6H2EEY2 A0A6H2EEY2 Dad PTHR13703:SF54 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;molecular function regulator activity#GO:0098772;sequence-specific double-stranded DNA binding#GO:1990837;molecular function inhibitor activity#GO:0140678;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565 cellular response to growth factor stimulus#GO:0071363;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>RSmads#P01292 DROME|FlyBase=FBgn0034598|UniProtKB=A8DYK5 A8DYK5 Isha PTHR23140:SF4 RNA PROCESSING PROTEIN LD23810P INSULATOR SU(HW) MRNA ADAPTOR, ISOFORM B RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 DROME|FlyBase=FBgn0028685|UniProtKB=Q9W414 Q9W414 Rpt4 PTHR23073:SF31 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 10B isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to stress#GO:0006950;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;macromolecule catabolic process#GO:0009057;regulation of cellular component biogenesis#GO:0044087;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to stress#GO:0033554;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription initiation#GO:2000142;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;response to endoplasmic reticulum stress#GO:0034976 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0031703|UniProtKB=Q9VMR6 Q9VMR6 Acsf2 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;ligase#PC00142 DROME|FlyBase=FBgn0039531|UniProtKB=Q9VB17 Q9VB17 Dmel\CG5611 PTHR43802:SF1 ENOYL-COA HYDRATASE IP11341P-RELATED metabolite interconversion enzyme#PC00262;hydratase#PC00120 DROME|FlyBase=FBgn0036999|UniProtKB=Q86PD7 Q86PD7 isoQC PTHR12283:SF5 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;acyltransferase activity#GO:0016746;binding#GO:0005488;small molecule binding#GO:0036094;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;zinc ion binding#GO:0008270;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 DROME|FlyBase=FBgn0039805|UniProtKB=Q9VA32 Q9VA32 Cpr100A PTHR10380:SF160 CUTICLE PROTEIN CUTICULAR PROTEIN 100A extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0033224|UniProtKB=Q0E9G3 Q0E9G3 Nop17l PTHR22997:SF12 PIH1 DOMAIN-CONTAINING PROTEIN 1 LD09868P-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0042125|UniProtKB=Q9I7N2 Q9I7N2 Dmel\CG18787 PTHR46527:SF1 NUCLEOPORIN-LIKE PROTEIN 2 NUCLEOPORIN NUP42 transporter#PC00227 DROME|FlyBase=FBgn0267252|UniProtKB=Q9NFZ3 Q9NFZ3 Ggamma30A PTHR15936:SF2 GUANINE NUCLEOTIDE-BINDING PROTEIN G I /G S /G O GAMMA-13 SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-13 binding#GO:0005488;protein binding#GO:0005515 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 G-protein#PC00020;heterotrimeric G-protein#PC00117;protein-binding activity modulator#PC00095 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Wnt signaling pathway#P00057>Ggamma#P01465 DROME|FlyBase=FBgn0261397|UniProtKB=A1Z6Z8 A1Z6Z8 didum PTHR13140:SF880 MYOSIN DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0052649|UniProtKB=Q9VYI6 Q9VYI6 Coq8 PTHR43851:SF3 FAMILY NOT NAMED COENZYME Q8 ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 DROME|FlyBase=FBgn0001145|UniProtKB=P20478 P20478 Gs2 PTHR20852:SF57 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE 2 CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 DROME|FlyBase=FBgn0030239|UniProtKB=Q9VZ64 Q9VZ64 Pgls PTHR11054:SF0 6-PHOSPHOGLUCONOLACTONASE 6-PHOSPHOGLUCONOLACTONASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;6-phosphogluconolactonase activity#GO:0017057;hydrolase activity#GO:0016787 NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0036837|UniProtKB=Q86BI9 Q86BI9 Dmel\CG18135 PTHR22958:SF43 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 DROME|FlyBase=FBgn0030723|UniProtKB=Q9VXK1 Q9VXK1 dpr18 PTHR23279:SF48 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 18 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252 DROME|FlyBase=FBgn0020906|UniProtKB=Q9VMX7 Q9VMX7 Jon25Bi PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0262954|UniProtKB=Q6IGE3 Q6IGE3 Polr2K PTHR12056:SF2 DNA-DIRECTED RNA POLYMERASES I, II, AND III DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0032290|UniProtKB=Q9VKR2 Q9VKR2 Dmel\CG6443 PTHR12775:SF0 PROTEIN C20ORF43 HOMOLOG REPLICATION TERMINATION FACTOR 2 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0261068|UniProtKB=Q9VJI7 Q9VJI7 LSm7 PTHR10553:SF44 SMALL NUCLEAR RIBONUCLEOPROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U6 snRNP#GO:0005688;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0051648|UniProtKB=Q9VMQ6 Q9VMQ6 Cox11 PTHR21320:SF8 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0034380|UniProtKB=Q8MSY4 Q8MSY4 Vps51 PTHR15954:SF4 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;Golgi organization#GO:0007030;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0037317|UniProtKB=Q59E05 Q59E05 Dmel\CG14667 PTHR24406:SF42 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED FI01110P-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0034180|UniProtKB=A4UZL3 A4UZL3 Ehbp1 PTHR23167:SF97 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EPS15 HOMOLOGY DOMAIN CONTAINING PROTEIN-BINDING PROTEIN 1, ISOFORM F actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0028490|UniProtKB=Q9VKG4 Q9VKG4 Dmel\CG31705 PTHR38572:SF1 BCDNA.GH07269-RELATED BCDNA.GH07269-RELATED DROME|FlyBase=FBgn0031779|UniProtKB=Q9VMH4 Q9VMH4 Dmel\CG9175 PTHR23284:SF0 PROLACTIN REGULATORY ELEMENT BINDING PROTEIN GUANINE NUCLEOTIDE-EXCHANGE FACTOR SEC12 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0037935|UniProtKB=Q9VGJ7 Q9VGJ7 Dmel\CG6834 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0001235|UniProtKB=O46339 O46339 hth PTHR11850:SF266 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN HOMOTHORAX sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;embryonic pattern specification#GO:0009880;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;eye development#GO:0001654;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0030617|UniProtKB=A8JUX3 A8JUX3 CT26106 PTHR19325:SF497 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN defense/immunity protein#PC00090;complement component#PC00078 DROME|FlyBase=FBgn0039273|UniProtKB=Q9VBY3 Q9VBY3 shams PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 DROME|FlyBase=FBgn0034649|UniProtKB=Q9W2E4 Q9W2E4 PIG-M PTHR12886:SF0 PIG-M MANNOSYLTRANSFERASE GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, CATALYTIC SUBUNIT mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mannosyltransferase complex#GO:0031501 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0040773|UniProtKB=Q7JW00 Q7JW00 COX7C PTHR13313:SF0 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transporter complex#GO:1990351;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 oxidoreductase#PC00176;oxidase#PC00175 DROME|FlyBase=FBgn0051029|UniProtKB=Q8IMJ2 Q8IMJ2 CG2164 PTHR39079:SF1 FI08034P-RELATED GH11706P-RELATED DROME|FlyBase=FBgn0035586|UniProtKB=Q9VRJ2 Q9VRJ2 Fitm2 PTHR23129:SF0 ACYL-COENZYME A DIPHOSPHATASE FITM2 ACYL-COENZYME A DIPHOSPHATASE FITM2 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular component assembly#GO:0022607;homeostatic process#GO:0042592;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;lipid homeostasis#GO:0055088;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;lipid storage#GO:0019915;cellular component organization or biogenesis#GO:0071840;lipid droplet organization#GO:0034389;organelle assembly#GO:0070925;chemical homeostasis#GO:0048878 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 DROME|FlyBase=FBgn0020653|UniProtKB=P91938 P91938 Trxr1 PTHR48105:SF37 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN-DISULFIDE REDUCTASE (NADPH) oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035 cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0031050|UniProtKB=Q9VWE8 Q9VWE8 Arp10 PTHR11937:SF14 ACTIN ACTIN-RELATED PROTEIN 10 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 localization#GO:0051179;cellular localization#GO:0051641;axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;retrograde axonal transport#GO:0008090;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;mitochondrion localization#GO:0051646;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;axo-dendritic transport#GO:0008088;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 DROME|FlyBase=FBgn0010052|UniProtKB=A1ZA98 A1ZA98 Jhe PTHR11559:SF428 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE esterase#PC00097 DROME|FlyBase=FBgn0039184|UniProtKB=Q9VC92 Q9VC92 Dmel\CG6432 PTHR43347:SF5 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 ligase#PC00142;metabolite interconversion enzyme#PC00262 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 DROME|FlyBase=FBgn0010014|UniProtKB=P48451 P48451 CanB PTHR45942:SF1 Calcineurin subunit B PROTEIN PHOSPHATASE 3 REGULATORY SUBUNIT B, ALPHA protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;calcineurin-mediated signaling#GO:0097720;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>Calcineurin#P01446 DROME|FlyBase=FBgn0054049|UniProtKB=A8WHB7 A8WHB7 CG34049-RA PTHR10334:SF565 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0036346|UniProtKB=Q9VU50 Q9VU50 Dmel\CG11251 PTHR42796:SF4 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED OXALOACETATE TAUTOMERASE FAHD2A, MITOCHONDRIAL hydrolase#PC00121 DROME|FlyBase=FBgn0035109|UniProtKB=Q9W0T9 Q9W0T9 Dmel\CG13876 PTHR21084:SF1 DENSE INCISORS SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 38 DROME|FlyBase=FBgn0259741|UniProtKB=B7Z137 B7Z137 Dmel\CG42395 PTHR43461:SF1 TRANSMEMBRANE PROTEIN 256 TRANSMEMBRANE PROTEIN 256 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038858|UniProtKB=Q9VDE2 Q9VDE2 Dmel\CG5793 PTHR11820:SF7 ACYLPYRUVASE OXALOACETATE TAUTOMERASE FAHD1, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0040366|UniProtKB=Q9V3X8 Q9V3X8 EG:BACR42I17.11 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0016070|UniProtKB=Q23972 Q23972 smg PTHR12515:SF5 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 DROME|FlyBase=FBgn0027054|UniProtKB=Q9V345 Q9V345 CSN4 PTHR10855:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 COP9 SIGNALOSOME COMPLEX SUBUNIT 4 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180 protease#PC00190 DROME|FlyBase=FBgn0032090|UniProtKB=Q9VLF1 Q9VLF1 Dmel\CG9582 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0016978|UniProtKB=P17133 P17133 snRNP-U1-70K PTHR13952:SF5 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;snRNA binding#GO:0017069;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0035847|UniProtKB=Q9VSE7 Q9VSE7 mthl7 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0050340|UniProtKB=A1Z7X3 A1Z7X3 Dmel\CG30340 PTHR24235:SF35 NEUROPEPTIDE Y RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0267398|UniProtKB=Q8SXI2 Q8SXI2 Yeti PTHR48407:SF1 CRANIOFACIAL DEVELOPMENT PROTEIN 1 HETEROCHROMATIN-STABILIZING PROTEIN CFDP1 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;Swr1 complex#GO:0000812;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0267449|UniProtKB=B4F7L9 B4F7L9 WDY PTHR44324:SF6 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN ON Y CHROMOSOME DROME|FlyBase=FBgn0261705|UniProtKB=Q9W1W2 Q9W1W2 CG9895 PTHR23235:SF197 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0038814|UniProtKB=A0A0B4KGJ7 A0A0B4KGJ7 Dmel\CG15923 PTHR21274:SF0 MECKELIN MECKELIN plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;ciliary transition zone#GO:0035869 DROME|FlyBase=FBgn0050021|UniProtKB=A1Z8G0 A1Z8G0 metro PTHR23122:SF42 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MENAGE A TROIS, ISOFORM A cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032223|UniProtKB=Q9VKZ0 Q9VKZ0 GATAd PTHR10071:SF340 TRANSCRIPTION FACTOR GATA FAMILY MEMBER FI19405P1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032169|UniProtKB=Q9VL59 Q9VL59 CG4709 PTHR46297:SF1 ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0027503|UniProtKB=Q9Y0Z1 Q9Y0Z1 Dmel\CG11970 PTHR13052:SF3 NFRKB-RELATED NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN protein binding#GO:0005515;binding#GO:0005488;protease binding#GO:0002020;enzyme binding#GO:0019899 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0030082|UniProtKB=Q9W396 Q9W396 HP1b PTHR22812:SF162 CHROMOBOX PROTEIN CHROMOBOX 3 chromatin binding#GO:0003682;binding#GO:0005488 heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0038312|UniProtKB=Q9VFA2 Q9VFA2 Zip88E PTHR11040:SF169 ZINC/IRON TRANSPORTER FI24038P1 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0029798|UniProtKB=Q9W484 Q9W484 Rtel1 PTHR11472:SF34 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER REGULATOR OF TELOMERE ELONGATION HELICASE 1 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;carbohydrate derivative binding#GO:0097367;nucleic acid conformation isomerase activity#GO:0120545;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;helicase activity#GO:0004386;nucleotide binding#GO:0000166;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of telomere maintenance#GO:0032204;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular component organization#GO:0051129;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;telomere organization#GO:0032200;regulation of double-strand break repair#GO:2000779;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of metabolic process#GO:0009892;regulation of cellular component biogenesis#GO:0044087;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0040634|UniProtKB=Q9VPC2 Q9VPC2 Dmel\CG4186 PTHR46811:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0033508|UniProtKB=A1Z875 A1Z875 Obp46a PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0085289|UniProtKB=M9PFS9 M9PFS9 Dmel\CG34260 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0036795|UniProtKB=Q9VVQ6 Q9VVQ6 Dmel\CG18233 PTHR10869:SF216 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROCOLLAGEN-PROLINE 4-DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;oxidoreductase complex#GO:1990204;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031941|UniProtKB=Q9VLY0 Q9VLY0 ATPsynGL PTHR12386:SF12 ATP SYNTHASE SUBUNIT ATP SYNTHASE F(0) COMPLEX SUBUNIT G, MITOCHONDRIAL-RELATED proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;oxidative phosphorylation#GO:0006119;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293 organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 DROME|FlyBase=FBgn0008635|UniProtKB=P45437 P45437 betaCOP PTHR10635:SF0 COATOMER SUBUNIT BETA COATOMER SUBUNIT BETA intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0085451|UniProtKB=Q9VWP5 Q9VWP5 htk PTHR13964:SF27 RBP-RELATED HAT-TRICK, ISOFORM D double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 DROME|FlyBase=FBgn0030686|UniProtKB=Q9VXQ0 Q9VXQ0 mRpL3 PTHR11229:SF8 50S RIBOSOMAL PROTEIN L3 LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 DROME|FlyBase=FBgn0033663|UniProtKB=Q3YMU0 Q3YMU0 ERp60 PTHR18929:SF132 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 chaperone#PC00072 DROME|FlyBase=FBgn0032535|UniProtKB=Q9VJV2 Q9VJV2 Ance-2 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0035122|UniProtKB=Q9W0S6 Q9W0S6 mRpL17 PTHR14413:SF24 RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0052277|UniProtKB=Q8IRE1 Q8IRE1 Dmel\CG32277 PTHR24276:SF97 POLYSERASE-RELATED GH13245P2-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032246|UniProtKB=Q9VKW1 Q9VKW1 Wdfy2 PTHR46189:SF1 LD41958P LD41958P membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 DROME|FlyBase=FBgn0020304|UniProtKB=E1JHR0 E1JHR0 drongo PTHR46134:SF3 DRONGO, ISOFORM F DRONGO, ISOFORM F cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0036948|UniProtKB=Q9VW90 Q9VW90 Dmel\CG7298 PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0004403|UniProtKB=C0HKA0 C0HKA0 RpS14a PTHR11759:SF1 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;translation#GO:0006412;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0014930|UniProtKB=O76206 O76206 Rfk PTHR22749:SF14 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;flavin-containing compound metabolic process#GO:0042726;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Flavin biosynthesis#P02741>FAD synthetase#P02936;Flavin biosynthesis#P02741>Riboflavin kinase#P02934 DROME|FlyBase=FBgn0034436|UniProtKB=Q4U2G8 Q4U2G8 Dmel\CG11961 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0010198|UniProtKB=P48149 P48149 RpS15Aa PTHR11758:SF16 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0031835|UniProtKB=X2J9P4 X2J9P4 Dpp10 PTHR11731:SF200 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED VENOM DIPEPTIDYL PEPTIDASE 4 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0034394|UniProtKB=Q5BIE4 Q5BIE4 CT42567 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0033140|UniProtKB=A0A0B4LEE2 A0A0B4LEE2 Dmel\CG12836 PTHR21255:SF65 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0261994|UniProtKB=Q9VC82 Q9VC82 CG18669 PTHR21398:SF6 AGAP007094-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0003486|UniProtKB=Q9VRM7 Q9VRM7 spo PTHR24303:SF31 HEME-BINDING MONOOXYGENASE FAMILY CYTOCHROME P450 307A1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0032021|UniProtKB=Q9VLP2 Q9VLP2 Dmel\CG7781 PTHR33562:SF14 ATILLA, ISOFORM B-RELATED-RELATED GEO08076P1 DROME|FlyBase=FBgn0085383|UniProtKB=A8JPX0 A8JPX0 CG12852 PTHR10352:SF93 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G TRIVET, ISOFORM I regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0263029|UniProtKB=A0A0B4K838 A0A0B4K838 Dmel\CG43324 PTHR13809:SF48 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell division#GO:0051301;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;cell population proliferation#GO:0008283;generation of neurons#GO:0048699;cell communication#GO:0007154;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;signal transduction#GO:0007165;cellular process#GO:0009987;asymmetric cell division#GO:0008356;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073 DROME|FlyBase=FBgn0036368|UniProtKB=Q9VU79 Q9VU79 EHR PTHR11920:SF515 GUANYLYL CYCLASE GUANYLATE CYCLASE lyase activity#GO:0016829;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanylate cyclase#PC00114;lyase#PC00144 DROME|FlyBase=FBgn0001206|UniProtKB=Q86CW5 Q86CW5 Hmr PTHR12243:SF67 MADF DOMAIN TRANSCRIPTION FACTOR COREPRESSOR OF PANGOLIN, ISOFORM A-RELATED regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0030931|UniProtKB=Q9VWT5 Q9VWT5 Xrcc2 PTHR46644:SF4 DNA REPAIR PROTEIN XRCC2 DNA REPAIR PROTEIN XRCC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;four-way junction DNA binding#GO:0000400 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;replication fork#GO:0005657;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0003944|UniProtKB=P83949 P83949 Ubx PTHR45659:SF21 HOMEOBOX PROTEIN HOX HOMEOTIC PROTEIN ULTRABITHORAX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 DROME|FlyBase=FBgn0029820|UniProtKB=Q9W461 Q9W461 Dmel\CG16721 PTHR12832:SF11 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 LD23868P signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0083141|UniProtKB=Q9VLZ8 Q9VLZ8 Spn28B PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0025633|UniProtKB=Q0KHX7 Q0KHX7 spdi PTHR23167:SF69 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED FI18193P1 cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038325|UniProtKB=Q9VF80 Q9VF80 Atg4b PTHR22624:SF49 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233 metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;autophagosome assembly#GO:0000045;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;macromolecule biosynthetic process#GO:0009059;autophagosome organization#GO:1905037;protein processing#GO:0016485;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;macroautophagy#GO:0016236;organelle assembly#GO:0070925;proteolysis#GO:0006508;protein metabolic process#GO:0019538;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 DROME|FlyBase=FBgn0052817|UniProtKB=Q8IRY8 Q8IRY8 Dmel\CG32817 PTHR14365:SF2 APOPTOSIS REGULATORY PROTEIN SIVA GEO12726P1-RELATED positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;immune system process#GO:0002376;regulation of immune response#GO:0050776;cell communication#GO:0007154 DROME|FlyBase=FBgn0039357|UniProtKB=Q9VBN7 Q9VBN7 CG4743 PTHR45667:SF9 S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN MITOCHONDRIAL S-ADENOSYLMETHIONINE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158 DROME|FlyBase=FBgn0265778|UniProtKB=Q9VMF3 Q9VMF3 PDZ-GEF PTHR23113:SF249 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;anatomical structure development#GO:0048856;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0030215|UniProtKB=Q9W2T5 Q9W2T5 BcDNA:AT26906 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle membrane contact site#GO:0044232;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0011836|UniProtKB=Q24325 Q24325 Taf2 PTHR15137:SF9 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2 binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 DROME|FlyBase=FBgn0250757|UniProtKB=Q9VBK1 Q9VBK1 kumpel PTHR42985:SF5 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER FI02094P-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293 sodium ion transport#GO:0006814;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0010078|UniProtKB=P48159 P48159 RpL23 PTHR11761:SF8 50S/60S RIBOSOMAL PROTEIN L14/L23 LARGE RIBOSOMAL SUBUNIT PROTEIN UL14 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0037973|UniProtKB=Q9VGF3 Q9VGF3 Dmel\CG18547 PTHR42686:SF1 GH17980P-RELATED GH17980P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0036442|UniProtKB=Q9VUG9 Q9VUG9 Dmel\CG13473 PTHR45663:SF11 GEO12009P1 THIOREDOXIN-1 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 DROME|FlyBase=FBgn0037012|UniProtKB=Q8SXY5 Q8SXY5 Rcd2 PTHR46439:SF3 CYSTEINE-RICH MOTOR NEURON 1 PROTEIN RE54525P DROME|FlyBase=FBgn0051472|UniProtKB=Q9VHZ5 Q9VHZ5 sgll PTHR10851:SF0 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXINE-5'-PHOSPHATE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;pyridine-containing compound metabolic process#GO:0072524 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061 DROME|FlyBase=FBgn0003896|UniProtKB=Q9VJ37 Q9VJ37 tup PTHR24204:SF8 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell fate specification#GO:0001708;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cell fate commitment#GO:0045165;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0260004|UniProtKB=Q9VDD3 Q9VDD3 Snmp1 PTHR11923:SF69 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 SENSORY NEURON MEMBRANE PROTEIN 1 cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0038173|UniProtKB=Q9VFS0 Q9VFS0 Adgf-C PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000 primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;purine-containing compound biosynthetic process#GO:0072522;purine nucleoside metabolic process#GO:0042278;nucleoside catabolic process#GO:0009164;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;nucleobase metabolic process#GO:0009112;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 deaminase#PC00088 DROME|FlyBase=FBgn0284243|UniProtKB=Q24560 Q24560 betaTub56D PTHR11588:SF504 TUBULIN TUBULIN BETA-1 CHAIN-RELATED ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 DROME|FlyBase=FBgn0033479|UniProtKB=A1Z838 A1Z838 PIG-N PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 extracellular matrix glycoprotein#PC00100 DROME|FlyBase=FBgn0041224|UniProtKB=Q8IMQ6 Q8IMQ6 Gr97a PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0053145|UniProtKB=A1Z8R6 A1Z8R6 GalT1 PTHR11214:SF314 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0030592|UniProtKB=Q9VY06 Q9VY06 Dm GMCdelta1 PTHR11552:SF154 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI04917P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036881|UniProtKB=M9PFX4 M9PFX4 Cpr76Bd PTHR12236:SF104 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 64AC-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0031228|UniProtKB=Q7K1C0 Q7K1C0 ND-15 PTHR21268:SF2 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 GH23780P DROME|FlyBase=FBgn0052590|UniProtKB=Q8IR45 Q8IR45 CG32590 PTHR21146:SF3 MEF2B PROTEIN BLOC-1-RELATED COMPLEX SUBUNIT 8 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 p38 MAPK pathway#P05918>MEF#P06023 DROME|FlyBase=FBgn0029785|UniProtKB=Q9W499 Q9W499 RpL35 PTHR45722:SF2 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 DROME|FlyBase=FBgn0026385|UniProtKB=P81922 P81922 Or47b PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0045502|UniProtKB=P58950 P58950 Gr10a PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038700|UniProtKB=Q8SXS7 Q8SXS7 Dmel\CG3734 PTHR11010:SF5 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED RE36938P-RELATED serine protease#PC00203 DROME|FlyBase=FBgn0261804|UniProtKB=Q9VJ94 Q9VJ94 CG7198 PTHR10443:SF47 MICROSOMAL DIPEPTIDASE DIPEPTIDASE catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0001148|UniProtKB=P09082 P09082 gsb PTHR45636:SF57 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PROTEIN GOOSEBERRY sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032934|UniProtKB=Q9VIE0 Q9VIE0 dLEM3 PTHR46427:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 STRUCTURE-SPECIFIC ENDONUCLEASE ANKLE1 DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520 cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 DROME|FlyBase=FBgn0037165|UniProtKB=Q9VNU0 Q9VNU0 LPP-like PTHR10165:SF103 LIPID PHOSPHATE PHOSPHATASE FI04477P-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;signal transduction#GO:0007165;lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;cell communication#GO:0007154;dephosphorylation#GO:0016311 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0015279|UniProtKB=P91634 P91634 Pi3K92E PTHR10048:SF118 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;organophosphate metabolic process#GO:0019637;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;cell motility#GO:0048870;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 kinase#PC00137 Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;p53 pathway feedback loops 2#P04398>PI3K#P04661;PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Ras Pathway#P04393>PI3K#P04567;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;PI3 kinase pathway#P00048>P110ACT#P01177;VEGF signaling pathway#P00056>PI3K#P01413;PI3 kinase pathway#P00048>p110#P01192;FGF signaling pathway#P00021>PI3K#P00640;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;EGF receptor signaling pathway#P00018>PI3K#P00557;Angiogenesis#P00005>PI3K#P00236 DROME|FlyBase=FBgn0038405|UniProtKB=Q9VEY0 Q9VEY0 Dmel\CG8927 PTHR10380:SF2 CUTICLE PROTEIN SUBFAMILY NOT NAMED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0086690|UniProtKB=Q400N2 Q400N2 Plp PTHR44981:SF2 PERICENTRIN-LIKE PROTEIN, ISOFORM F PERICENTRIN-LIKE PROTEIN, ISOFORM F cellular process#GO:0009987;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226 DROME|FlyBase=FBgn0034086|UniProtKB=Q7K1V1 Q7K1V1 Dmel\CG8441 PTHR13507:SF0 PRKR-INTERACTING PROTEIN 1 PRKR-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;enzyme inhibitor activity#GO:0004857;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0000351|UniProtKB=Q960N3 Q960N3 cort PTHR19918:SF52 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED PROTEIN CORTEX molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;binding#GO:0005488 biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163 intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0036967|UniProtKB=Q9VWB1 Q9VWB1 SCCRO4 PTHR12281:SF12 RP42 RELATED DCN1-LIKE PROTEIN 4 binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of protein modification process#GO:0031399;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of protein modification by small protein conjugation or removal#GO:1903320 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0264502|UniProtKB=A8JUR1 A8JUR1 CG15207 PTHR24215:SF7 RHO-GTPASE-ACTIVATING PROTEIN LRG1 SUBFAMILY NOT NAMED cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0260439|UniProtKB=P36179 P36179 Pp2A-29B PTHR10648:SF38 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;sister chromatid cohesion#GO:0007062;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;meiotic sister chromatid cohesion#GO:0051177;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 DROME|FlyBase=FBgn0029939|UniProtKB=A0A499JF18 A0A499JF18 Cph PTHR45993:SF6 B-CELL LYMPHOMA/LEUKEMIA 11 CHRONOPHAGE, ISOFORM K sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0036007|UniProtKB=Q9VT04 Q9VT04 path PTHR22950:SF154 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER-LIKE PROTEIN PATHETIC amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987;amino acid transport#GO:0006865 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0039201|UniProtKB=Q9VC70 Q9VC70 DZIP1 PTHR21502:SF12 ZINC FINGER PROTEIN DZIP1 CILIUM ASSEMBLY PROTEIN DZIP1L cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0028582|UniProtKB=Q9VS85 Q9VS85 lqf PTHR12276:SF115 EPSIN/ENT-RELATED FI19443P1 lipid binding#GO:0008289;protein binding#GO:0005515;phospholipid binding#GO:0005543;binding#GO:0005488;clathrin binding#GO:0030276 cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin-coated vesicle membrane#GO:0030665;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;vesicle coat#GO:0030120;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0034401|UniProtKB=A1ZBE9 A1ZBE9 MetRS PTHR45765:SF1 METHIONINE--TRNA LIGASE METHIONINE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 cytosol#GO:0005829;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0011230|UniProtKB=Q9VLT5 Q9VLT5 poe PTHR21725:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR4 E3 UBIQUITIN-PROTEIN LIGASE UBR4 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0032189|UniProtKB=Q9VL31 Q9VL31 Ripalpha PTHR31742:SF1 RPA-INTERACTING PROTEIN RPAIN RPA-INTERACTING PROTEIN protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0266369|UniProtKB=Q9VIH3 Q9VIH3 Mtp PTHR13024:SF0 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIACYLGLYCEROL TRANSFER PROTEIN macromolecule metabolic process#GO:0043170;lipoprotein metabolic process#GO:0042157;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;basal part of cell#GO:0045178;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0035483|UniProtKB=Q9VZJ9 Q9VZJ9 Mul1 PTHR12183:SF32 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 MITOCHONDRIAL E3 UBIQUITIN PROTEIN LIGASE 1 positive regulation of biological process#GO:0048518;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of developmental process#GO:0051094;protein stabilization#GO:0050821;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;positive regulation of mitochondrial fission#GO:0090141;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0037242|UniProtKB=Q9VN18 Q9VN18 March5 PTHR46283:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;metabolic process#GO:0008152;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;protein polyubiquitination#GO:0000209;regulation of mitochondrion organization#GO:0010821;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0015277|UniProtKB=Q9W1M7 Q9W1M7 Pi3K59F PTHR10048:SF7 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 process utilizing autophagic mechanism#GO:0061919;phosphatidylinositol phosphate biosynthetic process#GO:0046854;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;endocytosis#GO:0006897;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;metabolic process#GO:0008152;cellular component assembly#GO:0022607;glycerophospholipid metabolic process#GO:0006650;autophagy#GO:0006914;signal transduction#GO:0007165;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;vacuole organization#GO:0007033;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;organelle assembly#GO:0070925;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;pexophagy#GO:0000425;establishment of localization#GO:0051234;glycerophospholipid biosynthetic process#GO:0046474;transport#GO:0006810;lipid metabolic process#GO:0006629;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macroautophagy#GO:0016236;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;peroxisome#GO:0005777;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;extrinsic component of membrane#GO:0019898;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;microbody#GO:0042579;membrane#GO:0016020 kinase#PC00137 p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236;PDGF signaling pathway#P00047>PI3K#P01168;Ras Pathway#P04393>PI3K#P04567;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;EGF receptor signaling pathway#P00018>PI3K#P00557;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;T cell activation#P00053>PI3K#P01322;VEGF signaling pathway#P00056>PI3K#P01413;Integrin signalling pathway#P00034>PI3K#P00936 DROME|FlyBase=FBgn0030449|UniProtKB=Q9VYH1 Q9VYH1 Fer3HCH PTHR11431:SF75 FERRITIN FERRITIN metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 storage protein#PC00210 DROME|FlyBase=FBgn0034712|UniProtKB=Q9W273 Q9W273 Alp8 PTHR11596:SF91 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0037944|UniProtKB=A0A0B4KFN6 A0A0B4KFN6 Dmel\CG6923 PTHR14445:SF46 GRB10 INTERACTING GYF PROTEIN SUBFAMILY NOT NAMED translation regulator activity#GO:0045182 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0015295|UniProtKB=Q24145 Q24145 Shark PTHR24418:SF421 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SHARK phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 DROME|FlyBase=FBgn0037962|UniProtKB=Q9VGG6 Q9VGG6 Dnali1 PTHR13183:SF4 AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28 AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1 binding#GO:0005488;protein binding#GO:0005515 ciliary base#GO:0097546;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0038000|UniProtKB=Q9VGC1 Q9VGC1 Rsbp15 PTHR14952:SF21 ROPPORIN-1-LIKE PROTEIN IQ DOMAIN-CONTAINING PROTEIN E sperm motility#GO:0097722;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;sperm capacitation#GO:0048240;microtubule-based process#GO:0007017;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;protein localization to cilium#GO:0061512;cell motility#GO:0048870;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;spermatid development#GO:0007286;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;localization#GO:0051179;macromolecule localization#GO:0033036;male gamete generation#GO:0048232;developmental maturation#GO:0021700;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;cell maturation#GO:0048469 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0038033|UniProtKB=Q9VG86 Q9VG86 anon-WO0140519.58 PTHR11011:SF60 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0260943|UniProtKB=Q9VVE5 Q9VVE5 Rbp6 PTHR48032:SF18 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0030105|UniProtKB=Q9W370 Q9W370 Dmel\CG15369 PTHR12319:SF2 CYSTATIN-RELATED CYSTATIN-LIKE PROTEIN-RELATED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0053490|UniProtKB=Q8MST3 Q8MST3 CG6110 PTHR12086:SF12 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of signal transduction#GO:0009966;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987;regulation of calcineurin-NFAT signaling cascade#GO:0070884;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of response to stimulus#GO:0048583;flagellated sperm motility#GO:0030317;reproductive process#GO:0022414;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of metal ion transport#GO:0010959;sperm motility#GO:0097722;regulation of biological process#GO:0050789;cilium-dependent cell motility#GO:0060285;regulation of signaling#GO:0023051;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;regulation of intracellular signal transduction#GO:1902531 cytoplasmic microtubule#GO:0005881;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0040007|UniProtKB=Q9W5N2 Q9W5N2 RpL38 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 LARGE RIBOSOMAL SUBUNIT PROTEIN EL38 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0044030|UniProtKB=Q9VWI3 Q9VWI3 mRpS14 PTHR19836:SF31 30S RIBOSOMAL PROTEIN S14 SMALL RIBOSOMAL SUBUNIT PROTEIN US14M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467 membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 DROME|FlyBase=FBgn0030101|UniProtKB=Q9W375 Q9W375 Dmel\CG12118 PTHR13192:SF3 MY011 PROTEIN COBALAMIN TRAFFICKING PROTEIN CBLD tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0003511|UniProtKB=P07665 P07665 Sry-beta PTHR24409:SF417 ZINC FINGER PROTEIN 142 SERENDIPITY LOCUS PROTEIN BETA-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0264598|UniProtKB=Q7KVY9 Q7KVY9 PsGEF PTHR46848:SF1 REGULATOR OF G-PROTEIN SIGNALING 3 REGULATOR OF G PROTEIN SIGNALING 3 membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 DROME|FlyBase=FBgn0032748|UniProtKB=Q9VJ08 Q9VJ08 TU37B1 PTHR16195:SF16 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 14 DROME|FlyBase=FBgn0039424|UniProtKB=Q9VBF6 Q9VBF6 ppk15 PTHR11690:SF157 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 15-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0261999|UniProtKB=Q8IP22 Q8IP22 Ca-Ma2d PTHR10166:SF31 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED CA[2+] CHANNEL MUSCLE-SPECIFIC ALPHA2_DELTA SUBUNIT, ISOFORM A calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;transporter#PC00227 DROME|FlyBase=FBgn0039849|UniProtKB=Q9V9X4 Q9V9X4 Mri1 PTHR43475:SF1 METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;purine-containing compound metabolic process#GO:0072521;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 isomerase#PC00135 DROME|FlyBase=FBgn0038020|UniProtKB=Q9VGA0 Q9VGA0 GstD9 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0032074|UniProtKB=Q9VLH1 Q9VLH1 Tsp29Fa PTHR19282:SF456 TETRASPANIN FI23944P1-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0259938|UniProtKB=Q9VGZ5 Q9VGZ5 cwo PTHR10985:SF141 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR CWO transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA biosynthetic process#GO:1902679;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0036405|UniProtKB=Q9VUC3 Q9VUC3 Dmel\CG6833 PTHR12801:SF158 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 4 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;DNA catabolic process#GO:0006308;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DROME|FlyBase=FBgn0036550|UniProtKB=Q9VUW1 Q9VUW1 cg17026 PTHR20854:SF25 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 DROME|FlyBase=FBgn0032339|UniProtKB=Q9VKK2 Q9VKK2 Wdr59 PTHR46170:SF1 GATOR COMPLEX PROTEIN WDR59 GATOR2 COMPLEX PROTEIN WDR59 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;regulation of TORC1 signaling#GO:1903432;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to nutrient levels#GO:0031667;response to stress#GO:0006950;positive regulation of TORC1 signaling#GO:1904263;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cellular response to amino acid starvation#GO:0034198 membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0036738|UniProtKB=Q8T4A8 Q8T4A8 Dmel\CG7542 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0030286|UniProtKB=Q9VZ08 Q9VZ08 Gapvd1 PTHR23101:SF25 RAB GDP/GTP EXCHANGE FACTOR GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899 intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0015351|UniProtKB=Q9VER8 Q9VER8 Mettl4 PTHR12829:SF4 N6-ADENOSINE-METHYLTRANSFERASE LD37858P catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0030613|UniProtKB=Q9VXY2 Q9VXY2 Rab3-GEF PTHR13008:SF7 MAP-KINASE ACTIVATING DEATH DOMAIN PROTEIN MADD /DENN/AEX-3 C.ELEGANS MAP KINASE-ACTIVATING DEATH DOMAIN PROTEIN enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;regulation of intracellular signal transduction#GO:1902531 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Apoptosis signaling pathway#P00006>MADD#P00267 DROME|FlyBase=FBgn0031791|UniProtKB=Q9VMG0 Q9VMG0 AANATL2 PTHR20905:SF33 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0039798|UniProtKB=Q9VA44 Q9VA44 c-SP11 PTHR24256:SF527 TRYPTASE-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Toll pathway-drosophila#P06217>EA#P06339 DROME|FlyBase=FBgn0032810|UniProtKB=Q9VIT5 Q9VIT5 Fire-like PTHR15422:SF45 OS05G0565100 PROTEIN ASCORBATE FERRIREDUCTASE (TRANSMEMBRANE) DROME|FlyBase=FBgn0034484|UniProtKB=A1ZBR6 A1ZBR6 Dmel\CG11044 PTHR20872:SF1 FAMILY NOT NAMED F-BOX DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0036495|UniProtKB=Q7KUM2 Q7KUM2 CG7489 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0037672|UniProtKB=Q9VHG3 Q9VHG3 sage PTHR20937:SF3 IP14615P IP14615P transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;mesoderm morphogenesis#GO:0048332;gastrulation#GO:0007369;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;mesoderm formation#GO:0001707;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of gene expression#GO:0010468;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;mesoderm development#GO:0007498;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0039731|UniProtKB=Q9VAC8 Q9VAC8 Sas-6 PTHR44281:SF6 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;centriole replication#GO:0007099;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0001197|UniProtKB=P08985 P08985 His2Av PTHR23430:SF7 HISTONE H2A HISTONE H2A.V structural molecule activity#GO:0005198 cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0036009|UniProtKB=Q9VT08 Q9VT08 Or67a PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034660|UniProtKB=Q9W2C9 Q9W2C9 Loxl2 PTHR45817:SF4 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE-LIKE-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0052557|UniProtKB=Q9VX11 Q9VX11 Mco4 PTHR11709:SF539 MULTI-COPPER OXIDASE FI03373P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 oxidase#PC00175 DROME|FlyBase=FBgn0000261|UniProtKB=P17336 P17336 Cat PTHR11465:SF9 CATALASE CATALASE binding#GO:0005488;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity#GO:0016491 response to stress#GO:0006950;cellular process#GO:0009987;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to chemical#GO:0042221;hydrogen peroxide metabolic process#GO:0042743;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to oxygen-containing compound#GO:1901700;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;mitochondrion#GO:0005739;peroxisome#GO:0005777 peroxidase#PC00180 DROME|FlyBase=FBgn0053517|UniProtKB=Q8IS44 Q8IS44 Dop2R PTHR24248:SF125 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE D2-LIKE RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0019936|UniProtKB=P55828 P55828 RpS20 PTHR11700:SF8 30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US10 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 DROME|FlyBase=FBgn0035019|UniProtKB=Q9W155 Q9W155 Ir60e PTHR42643:SF39 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 56A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0285950|UniProtKB=P36241 P36241 RpL19 PTHR10722:SF0 60S RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN EL19 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 DROME|FlyBase=FBgn0030659|UniProtKB=Q9VXT1 Q9VXT1 Dmel\CG9215 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0250753|UniProtKB=Q9VNE2 Q9VNE2 kra PTHR14208:SF2 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN PROTEIN KRASAVIETZ intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0037750|UniProtKB=Q0KI93 Q0KI93 Whamy PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED ACTIN NUCLEATION-PROMOTING FACTOR WAS-RELATED enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267 regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0036992|UniProtKB=Q9VPF3 Q9VPF3 Hpd PTHR11959:SF16 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0045495|UniProtKB=Q9VM08 Q9VM08 Gr28b PTHR21143:SF104 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 8A-RELATED neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0035878|UniProtKB=Q9VSI1 Q9VSI1 Dmel\CG7182 PTHR19375:SF518 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN AA-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 DROME|FlyBase=FBgn0029890|UniProtKB=Q9W3X5 Q9W3X5 Fum2 PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 DROME|FlyBase=FBgn0031857|UniProtKB=Q8IPJ3 Q8IPJ3 LUBEL PTHR16004:SF2 RING FINGER PROTEIN 31-RELATED E3 UBIQUITIN-PROTEIN LIGASE LUBEL ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;modification-dependent protein binding#GO:0140030;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin binding#GO:0043130;polyubiquitin modification-dependent protein binding#GO:0031593;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035854|UniProtKB=Q9VSF4 Q9VSF4 CG8005 PTHR11703:SF0 DEOXYHYPUSINE SYNTHASE DEOXYHYPUSINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;biogenic amine metabolic process#GO:0006576 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0036221|UniProtKB=Q9VTQ5 Q9VTQ5 Dmel\CG11588 PTHR46107:SF3 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0036985|UniProtKB=Q9VPG1 Q9VPG1 zye PTHR46560:SF6 CYPHER, ISOFORM B ZYE developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell morphogenesis#GO:0000902 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 DROME|FlyBase=FBgn0014391|UniProtKB=Q9VXN2 Q9VXN2 sun PTHR12448:SF0 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT EPSILON, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;oxidative phosphorylation#GO:0006119;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 ATP synthase#PC00002 DROME|FlyBase=FBgn0053461|UniProtKB=A1ZA41 A1ZA41 Dmel\CG33461 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0033897|UniProtKB=A0A0B4KF25 A0A0B4KF25 Rcd1 PTHR13136:SF16 TESTIS DEVELOPMENT PROTEIN PRTD KAT8 REGULATORY NSL COMPLEX SUBUNIT 3 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248 DROME|FlyBase=FBgn0039354|UniProtKB=Q9VBP0 Q9VBP0 Lgr3 PTHR24372:SF84 GLYCOPROTEIN HORMONE RECEPTOR FI21465P1 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0263031|UniProtKB=A0A0B4K870 A0A0B4K870 Dmel\CG43326 PTHR23292:SF6 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16602P1-RELATED transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032029|UniProtKB=Q7K3Z8 Q7K3Z8 Dmel\CG17292 PTHR11610:SF37 LIPASE GH01208P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0003862|UniProtKB=P20659 P20659 trx PTHR45838:SF4 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE TRITHORAX histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0039370|UniProtKB=Q9VBM4 Q9VBM4 Dmel\CG4956 PTHR22883:SF511 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 establishment of localization#GO:0051234;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;protein targeting to membrane#GO:0006612;developmental process#GO:0032502;developmental maturation#GO:0021700;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting#GO:0006605;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0262081|UniProtKB=Q8INJ8 Q8INJ8 Csk PTHR24418:SF474 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 DROME|FlyBase=FBgn0259229|UniProtKB=Q9VPZ4 Q9VPZ4 Dmel\CG42329 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0051719|UniProtKB=Q9VKV0 Q9VKV0 RluA-1 PTHR21600:SF40 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD2 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 RNA processing factor#PC00147 DROME|FlyBase=FBgn0024362|UniProtKB=Q95RC0 Q95RC0 Naa30A PTHR45896:SF1 N-ALPHA-ACETYLTRANSFERASE 30 N-ALPHA-ACETYLTRANSFERASE 30 protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0053193|UniProtKB=Q9VCR6 Q9VCR6 sav PTHR47522:SF2 SALVADOR FAMILY WW DOMAIN-CONTAINING PROTEIN 1 PROTEIN SALVADOR HOMOLOG 1 negative regulation of cell population proliferation#GO:0008285;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;hippo signaling#GO:0035329;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DROME|FlyBase=FBgn0287185|UniProtKB=Q1JUZ1 Q1JUZ1 nvd PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0262139|UniProtKB=Q24119 Q24119 trh PTHR23043:SF26 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PROTEIN TRACHEALESS DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0045501|UniProtKB=P58951 P58951 Gr22a PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0035678|UniProtKB=Q9VRU0 Q9VRU0 Dmel\CG10469 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0035110|UniProtKB=Q8IRJ8 Q8IRJ8 thoc7 PTHR23405:SF5 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED THO COMPLEX SUBUNIT 7 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406 intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;transcription export complex#GO:0000346 DROME|FlyBase=FBgn0036212|UniProtKB=Q95TV5 Q95TV5 Dmel\CG11597 PTHR45619:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 DROME|FlyBase=FBgn0266441|UniProtKB=Q9VUK9 Q9VUK9 Dmel\CG45071 PTHR12243:SF51 MADF DOMAIN TRANSCRIPTION FACTOR LD27370P regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0052350|UniProtKB=Q8SX81 Q8SX81 Vps11 PTHR23323:SF24 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endomembrane system organization#GO:0010256;organelle fusion#GO:0048284;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;vesicle organization#GO:0016050;endosome organization#GO:0007032;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0031632|UniProtKB=Q9VR30 Q9VR30 anon-WO02059370.23 PTHR20958:SF9 GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN RE58324P DROME|FlyBase=FBgn0051133|UniProtKB=Q95T19 Q95T19 Slimp PTHR11778:SF2 SERYL-TRNA SYNTHETASE SERINE--TRNA SYNTHETASE-LIKE PROTEIN SLIMP RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;translation#GO:0006412;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0003079|UniProtKB=P11346 P11346 Raf PTHR44329:SF325 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RAF HOMOLOG SERINE_THREONINE-PROTEIN KINASE RAF MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;ERK1 and ERK2 cascade#GO:0070371;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>Raf#P01161;VEGF signaling pathway#P00056>Raf#P01417;Angiogenesis#P00005>Raf#P00243;Endothelin signaling pathway#P00019>Raf-1#P00587;EGF receptor signaling pathway#P00018>Raf-1#P00560;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Raf-1#P00843 DROME|FlyBase=FBgn0037222|UniProtKB=Q9VMZ3 Q9VMZ3 SP29 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0034425|UniProtKB=Q8SXZ6 Q8SXZ6 11906 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0002789|UniProtKB=P14318 P14318 Mp20 PTHR47385:SF27 CALPONIN MUSCLE-SPECIFIC PROTEIN 20 binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 DROME|FlyBase=FBgn0037709|UniProtKB=Q9VHB8 Q9VHB8 Bckdha PTHR43380:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 catalytic complex#GO:1902494;transferase complex#GO:1990234;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0034606|UniProtKB=Q86BG1 Q86BG1 ASPP PTHR24131:SF10 APOPTOSIS-STIMULATING OF P53 PROTEIN ANKYRIN-REPEAT, SH3-DOMAIN, AND PROLINE-RICH-REGION CONTAINING PROTEIN, ISOFORM B protein binding#GO:0005515;binding#GO:0005488 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction by p53 class mediator#GO:0072331;signaling#GO:0023052;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;programmed cell death#GO:0012501;apoptotic signaling pathway#GO:0097190;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular organelle#GO:0043229;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;nucleus#GO:0005634;cell-cell junction#GO:0005911;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0040503|UniProtKB=A1Z8L7 A1Z8L7 CK02422a PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0046875|UniProtKB=Q8MZ07 Q8MZ07 Obp83g PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0032769|UniProtKB=Q9VIY1 Q9VIY1 Dmel\CG10750 PTHR21683:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 42 HOMOLOG ISOFORM X1 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037530|UniProtKB=Q9VHY6 Q9VHY6 EMC1 PTHR21573:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 DROME|FlyBase=FBgn0034553|UniProtKB=Q9W2R1 Q9W2R1 Dmel\CG9993 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;organophosphate biosynthetic process#GO:0090407 ligase#PC00142 DROME|FlyBase=FBgn0290203|UniProtKB=Q9VL20 Q9VL20 Su(var)2-1 PTHR20338:SF6 NUCLEAR RESPIRATORY FACTOR 1 OVARIES ABSENT, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0028667|UniProtKB=Q8IQG3 Q8IQG3 Vha16-3 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0041092|UniProtKB=M9ND53 M9ND53 tai PTHR10684:SF4 NUCLEAR RECEPTOR COACTIVATOR TAIMAN, ISOFORM G transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713;binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to chemical stimulus#GO:0070887;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0033391|UniProtKB=A1Z7S4 A1Z7S4 anon-WO0242455.53 PTHR45683:SF18 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 32 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transporter#PC00227 DROME|FlyBase=FBgn0029943|UniProtKB=Q9W3R7 Q9W3R7 Atg5 PTHR13040:SF2 AUTOPHAGY PROTEIN 5 AUTOPHAGY PROTEIN 5 ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;piecemeal microautophagy of the nucleus#GO:0034727;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;cellular component organization#GO:0016043;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;cellular response to nutrient levels#GO:0031669;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagy of mitochondrion#GO:0000422;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;autophagosome#GO:0005776;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0265959|UniProtKB=P40421 P40421 rdgC PTHR45668:SF3 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE RDGC protein phosphatase#PC00195 DROME|FlyBase=FBgn0025838|UniProtKB=Q9W4X1 Q9W4X1 Dmel\CG2652 PTHR23195:SF15 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 4 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 general transcription factor#PC00259 DROME|FlyBase=FBgn0013348|UniProtKB=P47947 P47947 TpnC41C PTHR23050:SF221 CALCIUM BINDING PROTEIN FI07231P-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0260635|UniProtKB=Q24306 Q24306 Diap1 PTHR10044:SF174 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 1 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;enzyme regulator activity#GO:0030234;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of protein ubiquitination#GO:0031398;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396;regulation of apoptotic process#GO:0042981;regulation of protein modification process#GO:0031399;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0020238|UniProtKB=P92177 P92177 14-3-3epsilon PTHR18860:SF176 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 DROME|FlyBase=FBgn0023095|UniProtKB=A0A0S0WP14 A0A0S0WP14 caps PTHR45617:SF159 LEUCINE RICH REPEAT FAMILY PROTEIN CAPRICIOUS, ISOFORM E scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037147|UniProtKB=Q9VNW4 Q9VNW4 G6pdl PTHR23429:SF23 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;glucose-6-phosphate dehydrogenase activity#GO:0004345;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 DROME|FlyBase=FBgn0033029|UniProtKB=Q7K126 Q7K126 Not3 PTHR23326:SF1 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;CCR4-NOT complex#GO:0030014 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035772|UniProtKB=Q9NFP5 Q9NFP5 Sh3beta PTHR12232:SF15 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN HOMOLOG cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DROME|FlyBase=FBgn0014340|UniProtKB=O02193 O02193 mof PTHR10615:SF82 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT8 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;protein N-acyltransferase activity#GO:0140186 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0033355|UniProtKB=A1Z7L2 A1Z7L2 Dmel\CG13748 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0032002|UniProtKB=Q9VLR2 Q9VLR2 Dmel\CG8353 PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside catabolic process#GO:0009164;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 deaminase#PC00088 Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144 DROME|FlyBase=FBgn0041156|UniProtKB=Q9VSC2 Q9VSC2 exex PTHR24335:SF4 MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN EXTRA-EXTRA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0025360|UniProtKB=Q95RW8 Q95RW8 Optix PTHR10390:SF33 HOMEOBOX PROTEIN SIX PROTEIN OPTIX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036769|UniProtKB=Q7JZI2 Q7JZI2 Tsp74F PTHR19282:SF564 TETRASPANIN TETRASPANIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0261871|UniProtKB=Q59DZ4 Q59DZ4 dpr2 PTHR23279:SF4 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 2, ISOFORM F-RELATED cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020 DROME|FlyBase=FBgn0030959|UniProtKB=Q9VWQ3 Q9VWQ3 cg6961 PTHR19965:SF96 RNA AND EXPORT FACTOR BINDING PROTEIN POLYMERASE DELTA-INTERACTING PROTEIN 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;localization#GO:0051179 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037142|UniProtKB=Q9VNX0 Q9VNX0 NP_649372 PTHR28633:SF2 HERMANSKY-PUDLAK SYNDROME 3 PROTEIN HPS3 BIOGENESIS OF LYSOSOMAL ORGANELLES COMPLEX 2 SUBUNIT 1 DROME|FlyBase=FBgn0265342|UniProtKB=A0A0B4LF36 A0A0B4LF36 COX7CL PTHR13313:SF0 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0031906|UniProtKB=Q9VM20 Q9VM20 Dmel\CG5160 PTHR45704:SF16 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE DROME|FlyBase=FBgn0259727|UniProtKB=B7YZN8 B7YZN8 CG9865(uORF1) PTHR15590:SF0 CX9C MOTIF-CONTAINING PROTEIN 4 CX9C MOTIF-CONTAINING PROTEIN 4 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039611|UniProtKB=Q9VAS2 Q9VAS2 Nepl18 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0083943|UniProtKB=Q0KI89 Q0KI89 Dmel\CG34107 PTHR20899:SF1 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 1 PROTEIN DROME|FlyBase=FBgn0052985|UniProtKB=Q86BL9 Q86BL9 gi21430910 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0013263|UniProtKB=Q08605 Q08605 Trl PTHR23110:SF10 BTB DOMAIN TRANSCRIPTION FACTOR TRANSCRIPTION ACTIVATOR GAGA regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0036766|UniProtKB=Q9VVM2 Q9VVM2 Dmel\CG5506 PTHR31649:SF10 AGAP009604-PA IP19903P-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0032986|UniProtKB=Q9V9M8 Q9V9M8 Nubpl PTHR42961:SF4 IRON-SULFUR PROTEIN NUBPL IRON-SULFUR CLUSTER TRANSFER PROTEIN NUBPL iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0032553|UniProtKB=Q9VJR3 Q9VJR3 Dmel\CG4480 PTHR12242:SF49 OS02G0130600 PROTEIN-RELATED IP08657P-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0034084|UniProtKB=Q7JVH0 Q7JVH0 Dmel\CG8435 PTHR12111:SF1 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0051957|UniProtKB=Q8IQ13 Q8IQ13 CG31957 PTHR21641:SF0 TRANSLATION INITIATION FACTOR-RELATED RNA-BINDING PROTEIN EIF1AD-RELATED organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0027505|UniProtKB=Q9VKB9 Q9VKB9 Rab3-GAP PTHR12472:SF1 RAB3-GAP REGULATORY DOMAIN RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT molecular function regulator activity#GO:0098772;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 metabolic process#GO:0008152;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;synaptic signaling#GO:0099536;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;macroautophagy#GO:0016236;biological regulation#GO:0065007;establishment of protein localization to endoplasmic reticulum#GO:0072599;cell-cell signaling#GO:0007267;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;catabolic process#GO:0009056;signaling#GO:0023052 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022 DROME|FlyBase=FBgn0020660|UniProtKB=Q7PLL3 Q7PLL3 eIF4B PTHR23236:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC INITIATION FACTOR 4B-RELATED binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 DROME|FlyBase=FBgn0002905|UniProtKB=O18475 O18475 PolQ PTHR10133:SF64 DNA POLYMERASE I DNA POLYMERASE THETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 DNA-directed DNA polymerase#PC00018 DROME|FlyBase=FBgn0025709|UniProtKB=Q7K4A1 Q7K4A1 CNT2 PTHR10590:SF24 SODIUM/NUCLEOSIDE COTRANSPORTER CONCENTRATIVE NUCLEOSIDE TRANSPORTER 1-RELATED carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;nucleobase-containing compound transmembrane transporter activity#GO:0015932;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;nucleoside transmembrane transporter activity#GO:0005337;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0037874|UniProtKB=Q9VGS2 Q9VGS2 Tctp PTHR11991:SF23 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of catabolic process#GO:0009895;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037747|UniProtKB=Q59DX8 Q59DX8 Naa80 PTHR13538:SF4 N-ACETYLTRANSFERASE 6 N-ALPHA-ACETYLTRANSFERASE 80 transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;heterocyclic compound binding#GO:1901363;acetyltransferase activity#GO:0016407;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;N-acetyltransferase activity#GO:0008080;small molecule binding#GO:0036094;anion binding#GO:0043168;acyltransferase activity#GO:0016746;ion binding#GO:0043167 regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0034062|UniProtKB=Q4V5A5 Q4V5A5 Dmel\CG8388 PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0039630|UniProtKB=Q9VAQ2 Q9VAQ2 Dmel\CG11843 PTHR24260:SF147 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED DROME|FlyBase=FBgn0002735|UniProtKB=Q01070 Q01070 E(spl)mgamma-HLH PTHR10985:SF12 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED ENHANCER OF SPLIT M3 PROTEIN-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;pattern specification process#GO:0007389;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 DROME|FlyBase=FBgn0037250|UniProtKB=Q960G1 Q960G1 anon-WO0118547.308 PTHR13370:SF3 RNA METHYLASE-RELATED TRNA (GUANINE(10)-N(2))-METHYLTRANSFERASE TRMT11 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0013676|UniProtKB=P00417 P00417 mt:CoIII PTHR11403:SF7 CYTOCHROME C OXIDASE SUBUNIT III CYTOCHROME C OXIDASE SUBUNIT 3 oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324 electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0039402|UniProtKB=Q9VBI3 Q9VBI3 Vps2 PTHR10476:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2A late endosome to vacuole transport#GO:0045324;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0286203|UniProtKB=A0A0B4KF30 A0A0B4KF30 stw PTHR11709:SF232 MULTI-COPPER OXIDASE STRAW, ISOFORM G oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 oxidase#PC00175 DROME|FlyBase=FBgn0034880|UniProtKB=Q9W1M8 Q9W1M8 ItgaPS5 PTHR23220:SF83 INTEGRIN ALPHA INTEGRIN ALPHA-PS3-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941 DROME|FlyBase=FBgn0032997|UniProtKB=Q5LJP9 Q5LJP9 CG17486 PTHR45937:SF1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN CG17486 DROME|FlyBase=FBgn0025836|UniProtKB=X2JC00 X2JC00 RhoGAP1A PTHR23182:SF1 BREAKPOINT CLUSTER REGION PROTEIN BCR RHO GTPASE ACTIVATING PROTEIN AT 1A, ISOFORM E enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 postsynaptic density#GO:0014069;cell junction#GO:0030054;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;plasma membrane#GO:0005886 G-protein modulator#PC00022 DROME|FlyBase=FBgn0260874|UniProtKB=A8JNV9 A8JNV9 Ir76a PTHR42643:SF40 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 41A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0020299|UniProtKB=Q9VFI0 Q9VFI0 stumps PTHR16267:SF14 BANK1/PIK3AP1 FAMILY MEMBER STUMPS, ISOFORM E fibroblast growth factor receptor binding#GO:0005104;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;growth factor receptor binding#GO:0070851 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0052191|UniProtKB=Q8IQS4 Q8IQS4 CG5584 PTHR10342:SF264 ARYLSULFATASE MIP05773P-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0014870|UniProtKB=A1ZAK8 A1ZAK8 Psi PTHR10288:SF358 KH DOMAIN CONTAINING RNA BINDING PROTEIN P-ELEMENT SOMATIC INHIBITOR, ISOFORM C RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034166|UniProtKB=A1ZAL5 A1ZAL5 Dmel\CG6472 PTHR11610:SF169 LIPASE GH15759P-RELATED lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0085457|UniProtKB=A8JNS2 A8JNS2 Dmel\CG34428 PTHR21398:SF21 AGAP007094-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0034495|UniProtKB=Q4V3Z5 Q4V3Z5 Dmel\CG11788 PTHR13395:SF6 SISTER CHROMATID COHESION PROTEIN DCC1-RELATED SISTER CHROMATID COHESION PROTEIN DCC1 mitotic sister chromatid cohesion#GO:0007064;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 DROME|FlyBase=FBgn0260458|UniProtKB=Q9GN97 Q9GN97 PGRP-LD PTHR11022:SF73 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LD peptidoglycan muralytic activity#GO:0061783;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0028341|UniProtKB=Q9W323 Q9W323 Ptpmeg2 PTHR19134:SF449 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 9 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DROME|FlyBase=FBgn0038676|UniProtKB=Q9VE07 Q9VE07 Dmel\CG6026 PTHR10019:SF12 SNF5 SWI_SNF CHROMATIN-REMODELING COMPLEX SUBUNIT transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0011207|UniProtKB=P48612 P48612 pelo PTHR10853:SF11 PELOTA PROTEIN PELOTA HOMOLOG molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;rescue of stalled cytosolic ribosome#GO:0072344;regulation of biological process#GO:0050789;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;organelle disassembly#GO:1903008;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;organelle organization#GO:0006996;cellular process#GO:0009987;gene expression#GO:0010467;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;translational elongation#GO:0006414;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;translation#GO:0006412;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 translation release factor#PC00225 DROME|FlyBase=FBgn0010315|UniProtKB=Q7KUZ5 Q7KUZ5 CycD PTHR10177:SF527 CYCLINS CYCLIN D, ISOFORM D molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of cellular process#GO:0048522;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931 membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 Cell cycle#P00013>Cyclin D#P00484;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 DROME|FlyBase=FBgn0035206|UniProtKB=Q9W0H3 Q9W0H3 sturkopf PTHR13390:SF0 LIPASE LIPID DROPLET-ASSOCIATED HYDROLASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;lipid droplet organization#GO:0034389 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0003256|UniProtKB=P40417 P40417 rl PTHR24055:SF599 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE ERK-A kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>MAPK#P00269;FGF signaling pathway#P00021>ERK1-2#P00627;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Endothelin signaling pathway#P00019>ERK#P00566;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Parkinson disease#P00049>ERK#P01211;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293 DROME|FlyBase=FBgn0026160|UniProtKB=A0A6J3SHB9 A0A6J3SHB9 tna PTHR10782:SF108 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN TONALLI, ISOFORM E transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;SUMO transferase activity#GO:0019789;transcription regulator activity#GO:0140110;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678 protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;metabolic process#GO:0008152;protein sumoylation#GO:0016925;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;negative regulation of cellular process#GO:0048523;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0035710|UniProtKB=Q0E8H7 Q0E8H7 SP1173 PTHR16172:SF27 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE FI19426P1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036756|UniProtKB=Q9VVL0 Q9VVL0 Cln3 PTHR10981:SF0 BATTENIN BATTENIN homeostatic process#GO:0042592;microtubule-based movement#GO:0007018;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;organelle localization#GO:0051640;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;vesicle localization#GO:0051648;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;vacuolar transport#GO:0007034;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;intracellular chemical homeostasis#GO:0055082;receptor-mediated endocytosis#GO:0006898;vesicle cytoskeletal trafficking#GO:0099518;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;intracellular monoatomic ion homeostasis#GO:0006873;cytosolic transport#GO:0016482;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;post-Golgi vesicle-mediated transport#GO:0006892;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;vesicle-mediated transport#GO:0016192;amino acid transport#GO:0006865;Golgi vesicle transport#GO:0048193;chemical homeostasis#GO:0048878;microtubule-based process#GO:0007017;import into cell#GO:0098657 intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;vacuole#GO:0005773;Golgi apparatus#GO:0005794;lytic vacuole#GO:0000323 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0050467|UniProtKB=Q7K4H1 Q7K4H1 CG8185 PTHR23424:SF34 SERUM AMYLOID A LD40680P membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 transfer/carrier protein#PC00219;apolipoprotein#PC00052 DROME|FlyBase=FBgn0266669|UniProtKB=Q9VVG4 Q9VVG4 Sec3 PTHR16092:SF14 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668;cellular localization#GO:0051641;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;secretion by cell#GO:0032940;post-Golgi vesicle-mediated transport#GO:0006892 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;exocyst#GO:0000145;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell cortex#GO:0005938 membrane traffic protein#PC00150;SNARE protein#PC00034 DROME|FlyBase=FBgn0035875|UniProtKB=Q9VSH7 Q9VSH7 Cpr66Cb PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0031467|UniProtKB=Q9VQH5 Q9VQH5 Cpr23B PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053143|UniProtKB=Q9W233 Q9W233 Idit PTHR21104:SF2 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0038727|UniProtKB=Q9VDU8 Q9VDU8 SP19 PTHR24258:SF147 SERINE PROTEASE-RELATED FI16631P1-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0053463|UniProtKB=A1ZA59 A1ZA59 Dmel\CG33463 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0001276|UniProtKB=Q7KBL8 Q7KBL8 ix PTHR28314:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 DROME|FlyBase=FBgn0023441|UniProtKB=Q9BJZ5 Q9BJZ5 fus PTHR13976:SF25 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA-BINDING PROTEIN FUSILLI nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0025381|UniProtKB=O76902 O76902 rush PTHR46280:SF3 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 HOMOLOG DROME|FlyBase=FBgn0067629|UniProtKB=Q9VFF2 Q9VFF2 CG3641 PTHR46370:SF1 GPALPP MOTIFS-CONTAINING PROTEIN 1 GPALPP MOTIFS-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0286818|UniProtKB=P54399 P54399 Pdi PTHR18929:SF240 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;response to stress#GO:0006950;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0032513|UniProtKB=Q9VJZ2 Q9VJZ2 Stard7 PTHR19308:SF8 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 7, MITOCHONDRIAL DROME|FlyBase=FBgn0034509|UniProtKB=Q9V931 Q9V931 Obp57c PTHR11857:SF48 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 57C-RELATED sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0034900|UniProtKB=Q9W1K2 Q9W1K2 Dmel\CG12491 PTHR14369:SF0 SURFEIT LOCUS PROTEIN 6 SURFEIT LOCUS PROTEIN 6 RNA binding#GO:0003723;molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488 ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035252|UniProtKB=A0A0S0WGR0 A0A0S0WGR0 anon-WO0118547.268 PTHR11266:SF134 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 PEROXISOMAL MEMBRANE PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0027930|UniProtKB=A0A126GUP6 A0A126GUP6 MP1 PTHR24260:SF135 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED DROME|FlyBase=FBgn0086694|UniProtKB=Q9VRP9 Q9VRP9 Bre1 PTHR23163:SF0 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0033600|UniProtKB=A1Z8H4 A1Z8H4 Cpr47Ec PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0027793|UniProtKB=Q9W591 Q9W591 Dmel\CG14787 PTHR43459:SF1 ENOYL-COA HYDRATASE EG:BACN32G11.4 PROTEIN metabolite interconversion enzyme#PC00262;lyase#PC00144;hydratase#PC00120 DROME|FlyBase=FBgn0037638|UniProtKB=Q7KSU3 Q7KSU3 Dmel\CG8379 PTHR13608:SF3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0011817|UniProtKB=A0A4D6K823 A0A4D6K823 nmo PTHR24055:SF391 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;Wnt signaling pathway#P00057>Nemo-like Kinase#P01449;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Apoptosis signaling pathway#P00006>MAPK#P00269;FGF signaling pathway#P00021>ERK1-2#P00627;Endothelin signaling pathway#P00019>ERK#P00566;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;EGF receptor signaling pathway#P00018>ERK1-2#P00543 DROME|FlyBase=FBgn0003885|UniProtKB=P06605 P06605 alphaTub84D PTHR11588:SF501 TUBULIN TUBULIN ALPHA CHAIN GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 tubulin#PC00228;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0030063|UniProtKB=Q9W3C0 Q9W3C0 CG1789 PTHR12838:SF0 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035868|UniProtKB=Q9VSH0 Q9VSH0 CG7194 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED nucleotidyltransferase#PC00174;transferase#PC00220 DROME|FlyBase=FBgn0032670|UniProtKB=Q9VJ98 Q9VJ98 Dmel\CG5783 PTHR20958:SF10 GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN GH05617P-RELATED DROME|FlyBase=FBgn0040211|UniProtKB=Q9VKJ0 Q9VKJ0 Hgd PTHR11056:SF0 HOMOGENTISATE 1,2-DIOXYGENASE HOMOGENTISATE 1,2-DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0015929|UniProtKB=Q26454 Q26454 dpa PTHR11630:SF66 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM4 DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;cellular process#GO:0009987;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716 MCM complex#GO:0042555;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0261403|UniProtKB=Q7KJA9 Q7KJA9 sxc PTHR44366:SF1 UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035455|UniProtKB=Q9I7T6 Q9I7T6 Dmel\CG10862 PTHR24068:SF567 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME-RELATED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 DROME|FlyBase=FBgn0029880|UniProtKB=Q9W3Y5 Q9W3Y5 CG14443 PTHR47958:SF122 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE CG14443-RELATED ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386 macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA helicase#PC00032 DROME|FlyBase=FBgn0026401|UniProtKB=Q7PLI2 Q7PLI2 Nipped-B PTHR21704:SF18 NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED NIPPED-B PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 replication-born double-strand break repair via sister chromatid exchange#GO:1990414;nucleobase-containing compound metabolic process#GO:0006139;mitotic sister chromatid cohesion#GO:0007064;DNA damage response#GO:0006974;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;localization#GO:0051179;sister chromatid cohesion#GO:0007062;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0015799|UniProtKB=Q24472 Q24472 Rbf PTHR13742:SF17 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RE32990P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;negative regulation of cell cycle#GO:0045786;cellular developmental process#GO:0048869;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;negative regulation of cell cycle process#GO:0010948;negative regulation of mitotic cell cycle phase transition#GO:1901991;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0036844|UniProtKB=Q9VVW5 Q9VVW5 Mkp3 PTHR10159:SF541 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 DROME|FlyBase=FBgn0033640|UniProtKB=A1Z8N0 A1Z8N0 Dmel\CG13198 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0034614|UniProtKB=Q9W2I2 Q9W2I2 Dmel\CG9752 PTHR21314:SF0 QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 DROME|FlyBase=FBgn0032291|UniProtKB=Q9VKR1 Q9VKR1 Dmel\CG17118 PTHR12458:SF11 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;cellular component organization#GO:0016043;cilium assembly#GO:0060271;anatomical structure morphogenesis#GO:0009653;sperm motility#GO:0097722;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;motile cilium assembly#GO:0044458;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;anatomical structure formation involved in morphogenesis#GO:0048646 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;motile cilium#GO:0031514;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 DROME|FlyBase=FBgn0035965|UniProtKB=Q9VSU7 Q9VSU7 Use1 PTHR13050:SF7 USE1-LIKE PROTEIN VESICLE TRANSPORT PROTEIN USE1 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020 DROME|FlyBase=FBgn0029930|UniProtKB=Q9W3T1 Q9W3T1 Dmel\CG12541 PTHR21104:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0266450|UniProtKB=P08155 P08155 Kr-h1 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0001491|UniProtKB=O97454 O97454 l(1)10Bb PTHR19411:SF0 PROTEIN BUD31-RELATED PROTEIN BUD31 HOMOLOG mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0000117|UniProtKB=P18824 P18824 arm PTHR45976:SF1 ARMADILLO SEGMENT POLARITY PROTEIN ARMADILLO SEGMENT POLARITY PROTEIN transcription coactivator activity#GO:0003713;protein phosphatase binding#GO:0019903;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coregulator activity#GO:0003712;cell adhesion molecule binding#GO:0050839;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cell adhesion#GO:0007155;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 p53 pathway feedback loops 2#P04398>beta-catenin#P04670;Cadherin signaling pathway#P00012>betacatenin#P00463;Wnt signaling pathway#P00057>Beta-Catenin#P01432;Angiogenesis#P00005>beta catenin#P00187;Alzheimer disease-presenilin pathway#P00004>beta-catenin#P00156 DROME|FlyBase=FBgn0015544|UniProtKB=Q9V3E9 Q9V3E9 spag PTHR46423:SF1 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 DROME|FlyBase=FBgn0017545|UniProtKB=P55830 P55830 RpS3A PTHR11830:SF0 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0051664|UniProtKB=M9PC61 M9PC61 Dmel\CG31664 PTHR47890:SF1 LD24308P LD24308P DROME|FlyBase=FBgn0038013|UniProtKB=Q95RN0 Q95RN0 CG10038 PTHR21357:SF4 FAM172 FAMILY PROTEIN HOMOLOG CG10038 FAM172 FAMILY PROTEIN HOMOLOG CG10038 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0064126|UniProtKB=Q6NL44 Q6NL44 CG18238 PTHR46467:SF1 TETHER CONTAINING UBX DOMAIN FOR GLUT4 TETHER CONTAINING UBX DOMAIN FOR GLUT4 homeostatic process#GO:0042592;carbohydrate homeostasis#GO:0033500;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;glucose homeostasis#GO:0042593;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0030594|UniProtKB=Q9VY04 Q9VY04 fiz PTHR11552:SF229 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE ECDYSONE OXIDASE-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0000015|UniProtKB=P09087 P09087 Abd-B PTHR45874:SF4 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN ABDOMINAL-B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0267791|UniProtKB=A1ZBW0 A1ZBW0 HnRNP-K PTHR10288:SF356 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA splicing#GO:0043484;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034974|UniProtKB=Q7JRF0 Q7JRF0 Dmel\CG16786 PTHR39072:SF3 RE48511P RE48511P DROME|FlyBase=FBgn0032822|UniProtKB=Q9VIS0 Q9VIS0 cg10466 PTHR45880:SF1 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011 DROME|FlyBase=FBgn0041195|UniProtKB=Q9VK95 Q9VK95 Pkd2 PTHR10877:SF183 POLYCYSTIN FAMILY MEMBER AT14535P-RELATED ion channel#PC00133 DROME|FlyBase=FBgn0003961|UniProtKB=P16163 P16163 Uro PTHR42874:SF1 URICASE URICASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0000181|UniProtKB=Q7KM15 Q7KM15 bic PTHR10351:SF23 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0260858|UniProtKB=Q9W3M8 Q9W3M8 Ykt6 PTHR45806:SF1 SYNAPTOBREVIN HOMOLOG YKT6 SYNAPTOBREVIN HOMOLOG YKT6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 vesicle fusion#GO:0006906;catabolic process#GO:0009056;intra-Golgi vesicle-mediated transport#GO:0006891;cellular component organization#GO:0016043;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;vacuole fusion#GO:0097576;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;vacuole fusion, non-autophagic#GO:0042144;macroautophagy#GO:0016236;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;metabolic process#GO:0008152 autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;vesicle#GO:0031982;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773 DROME|FlyBase=FBgn0034422|UniProtKB=Q7K2B0 Q7K2B0 CG7137 PTHR12787:SF0 RIBOSOMAL RNA-PROCESSING PROTEIN 8 RIBOSOMAL RNA-PROCESSING PROTEIN 8 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649 cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleolus organization#GO:0007000;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0032880|UniProtKB=Q9VIK1 Q9VIK1 TM9SF2 PTHR10766:SF176 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0264324|UniProtKB=Q9VAS8 Q9VAS8 spg PTHR45653:SF12 DEDICATOR OF CYTOKINESIS SPONGE, ISOFORM E molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0022936|UniProtKB=O76513 O76513 CycH PTHR10026:SF8 CYCLIN CYCLIN-H enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 kinase activator#PC00138;kinase modulator#PC00140 DROME|FlyBase=FBgn0044051|UniProtKB=Q9VT50 Q9VT50 Ilp1 PTHR13647:SF4 INSULIN-LIKE PEPTIDE 2-RELATED INSULIN-LIKE PEPTIDE 1-RELATED DROME|FlyBase=FBgn0028561|UniProtKB=Q7KJP2 Q7KJP2 sut3 PTHR23503:SF127 SOLUTE CARRIER FAMILY 2 FI08437P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 carbohydrate transport#GO:0008643;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;carbohydrate transmembrane transport#GO:0034219;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0026391|UniProtKB=P81915 P81915 Or33b PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037773|UniProtKB=Q9VH45 Q9VH45 Dmel\CG5359 PTHR21255:SF7 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0031799|UniProtKB=Q9V3V3 Q9V3V3 Pez PTHR45706:SF1 TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 protein phosphatase#PC00195 DROME|FlyBase=FBgn0259231|UniProtKB=A8JUP8 A8JUP8 CCKLR-17D1 PTHR24238:SF84 G-PROTEIN COUPLED RECEPTOR CHOLECYSTOKININ-LIKE RECEPTOR AT 17D1-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0263231|UniProtKB=Q9VHP0 Q9VHP0 bel PTHR47958:SF216 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;reproductive process#GO:0022414;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA helicase#PC00032 DROME|FlyBase=FBgn0030407|UniProtKB=Q9VYL1 Q9VYL1 Fpgs1 PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739 ligase#PC00142 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 DROME|FlyBase=FBgn0283508|UniProtKB=C3KGN2 C3KGN2 nw PTHR22802:SF421 C-TYPE LECTIN SUPERFAMILY MEMBER MIP03875P signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0014396|UniProtKB=P49021 P49021 tim PTHR22940:SF6 TIMEOUT/TIMELESS-2 PROTEIN TIMELESS DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;DNA replication#GO:0006260;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;negative regulation of DNA-templated DNA replication#GO:2000104;DNA repair#GO:0006281;response to external stimulus#GO:0009605;macromolecule metabolic process#GO:0043170;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;DNA integrity checkpoint signaling#GO:0031570;regulation of primary metabolic process#GO:0080090;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0002441|UniProtKB=Q9VB52 Q9VB52 l(3)mbt PTHR12247:SF141 POLYCOMB GROUP PROTEIN LD05287P binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0033320|UniProtKB=A1Z7H7 A1Z7H7 Dmel\CG8586 PTHR24256:SF555 TRYPTASE-RELATED PHENOLOXIDASE-ACTIVATING FACTOR 2 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0259228|UniProtKB=O77086 O77086 C3G PTHR23113:SF224 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;positive regulation of neuron projection development#GO:0010976;Ras protein signal transduction#GO:0007265;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 Integrin signalling pathway#P00034>C3G#P00929 DROME|FlyBase=FBgn0031244|UniProtKB=Q9VPM9 Q9VPM9 Dmel\CG11601 PTHR10989:SF16 ANDROGEN-INDUCED PROTEIN 1-RELATED AT02829P-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436 DROME|FlyBase=FBgn0026238|UniProtKB=A1Z6E0 A1Z6E0 gus PTHR12245:SF11 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN PROTEIN GUSTAVUS enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0030587|UniProtKB=Q9VY11 Q9VY11 Dm GMCiota1 PTHR11552:SF208 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE RE36204P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0032077|UniProtKB=Q86BM0 Q86BM0 gh06087 PTHR43213:SF5 BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429 DROME|FlyBase=FBgn0034081|UniProtKB=A1ZAA9 A1ZAA9 ATPW PTHR13382:SF10 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B ATP SYNTHASE SUBUNIT S, MITOCHONDRIAL cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002 DROME|FlyBase=FBgn0035028|UniProtKB=Q9W145 Q9W145 Start1 PTHR46121:SF4 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome#GO:0005768;endosome membrane#GO:0010008;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane contact site#GO:0044232;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506 DROME|FlyBase=FBgn0032648|UniProtKB=Q9VJC4 Q9VJC4 Dmel\CG15144 PTHR22455:SF10 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 DROME|FlyBase=FBgn0036667|UniProtKB=Q9VVA8 Q9VVA8 kud PTHR13636:SF0 TRANSMEMBRANE PROTEIN 258 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT TMEM258 binding#GO:0005488;protein-containing complex binding#GO:0044877 response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;response to stimulus#GO:0050896 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0265140|UniProtKB=Q6QU65 Q6QU65 Meltrin PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0002917|UniProtKB=A8JUW5 A8JUW5 na PTHR46141:SF1 SODIUM LEAK CHANNEL NON-SELECTIVE PROTEIN SODIUM LEAK CHANNEL NALCN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 DROME|FlyBase=FBgn0051961|UniProtKB=Q95TP0 Q95TP0 Tbcc PTHR15139:SF0 TUBULIN FOLDING COFACTOR C TUBULIN-SPECIFIC CHAPERONE C microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0036597|UniProtKB=Q9VV21 Q9VV21 Dmel\CG4962 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0027055|UniProtKB=Q8SYG2 Q8SYG2 CSN3 PTHR10758:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 COP9 SIGNALOSOME COMPLEX SUBUNIT 3 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0005695|UniProtKB=Q01820 Q01820 gcl PTHR23231:SF17 GERM CELL-LESS PROTEIN GERM CELL-LESS 1, SPERMATOSIS ASSOCIATED ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0023169|UniProtKB=O18645 O18645 AMPKalpha PTHR24343:SF576 SERINE/THREONINE KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;localization#GO:0051179;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;cellular response to glucose starvation#GO:0042149;macromolecule localization#GO:0033036;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;regulation of TORC1 signaling#GO:1903432;intracellular protein localization#GO:0008104;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;negative regulation of TORC1 signaling#GO:1904262 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003731|UniProtKB=P04412 P04412 Egfr PTHR24416:SF566 TYROSINE-PROTEIN KINASE RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;system development#GO:0048731;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067 membrane#GO:0016020;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;EGF receptor signaling pathway#P00018>EGFR#P00542 DROME|FlyBase=FBgn0052463|UniProtKB=Q8IPZ0 Q8IPZ0 Tengl2 PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520 cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655 mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Apoptosis signaling pathway#P00006>endoG#P00279 DROME|FlyBase=FBgn0032833|UniProtKB=Q9VIQ8 Q9VIQ8 COX4 PTHR10707:SF10 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transporter complex#GO:1990351;organelle membrane#GO:0031090 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0027567|UniProtKB=Q9VT61 Q9VT61 Ciz1 PTHR15491:SF18 FAMILY NOT NAMED CIZ1 ZINC FINGER PROTEIN, ISOFORM A intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0035082|UniProtKB=Q9W0Y2 Q9W0Y2 CG2811 PTHR12510:SF4 TROPONIN C-AKIN-1 PROTEIN GAMMA-GLUTAMYLAMINECYCLOTRANSFERASE intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DROME|FlyBase=FBgn0011280|UniProtKB=P54192 P54192 Obp19d PTHR11857:SF42 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 19D-RELATED nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0267033|UniProtKB=Q9VY72 Q9VY72 mamo PTHR23110:SF104 BTB DOMAIN TRANSCRIPTION FACTOR MATERNAL GENE REQUIRED FOR MEIOSIS, ISOFORM H regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0035532|UniProtKB=Q9VZD8 Q9VZD8 CG15014 PTHR13452:SF10 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 DROME|FlyBase=FBgn0026207|UniProtKB=Q9GYU8 Q9GYU8 mbo PTHR13257:SF0 NUCLEOPORIN NUP84-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP88 organelle localization#GO:0051640;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA export from nucleus#GO:0006405;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;protein transport#GO:0015031;protein import into nucleus#GO:0006606;ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;gene expression#GO:0010467;protein export from nucleus#GO:0006611 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0026573|UniProtKB=A1Z8R2 A1Z8R2 ADD1 PTHR46357:SF1 TRANSCRIPTIONAL REGULATOR ATRX CHROMATIN REMODELER ATRX nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 chromatin remodeling#GO:0006338;replication fork processing#GO:0031297;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0031865|UniProtKB=Q9VM74 Q9VM74 Nha1 PTHR31102:SF24 FAMILY NOT NAMED NA[+]_H[+] HYDROGEN ANTIPORTER 1, ISOFORM A localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 DROME|FlyBase=FBgn0004650|UniProtKB=O76904 O76904 fs(1)N PTHR22918:SF6 SEMINAL PLASMA PROTEIN EG:8D8.1 PROTEIN-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0259200|UniProtKB=Q9VZY7 Q9VZY7 Dmel\CG42304 PTHR23399:SF2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0035425|UniProtKB=Q9VZS1 Q9VZS1 Cg17746 PTHR13832:SF565 PROTEIN PHOSPHATASE 2C PROTEIN-SERINE_THREONINE PHOSPHATASE hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 protein phosphatase#PC00195 DROME|FlyBase=FBgn0037878|UniProtKB=Q9VGR7 Q9VGR7 CG6693 PTHR44144:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 binding#GO:0005488;heat shock protein binding#GO:0031072;protein binding#GO:0005515 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0029955|UniProtKB=Q9W3Q4 Q9W3Q4 Dmel\CG15478 PTHR24330:SF10 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN B-H1-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0260749|UniProtKB=Q9VL07 Q9VL07 Utx PTHR14017:SF32 LYSINE-SPECIFIC DEMETHYLASE LD02225P binding#GO:0005488;histone modifying activity#GO:0140993;transcription regulatory region nucleic acid binding#GO:0001067;histone demethylase activity#GO:0032452;sequence-specific DNA binding#GO:0043565;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;dioxygenase activity#GO:0051213;DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;sequence-specific double-stranded DNA binding#GO:1990837;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0039196|UniProtKB=Q9VC79 Q9VC79 Dmel\CG17781 PTHR21398:SF1 AGAP007094-PA FI03705P DROME|FlyBase=FBgn0032602|UniProtKB=Q9VJI4 Q9VJI4 ppk17 PTHR11690:SF222 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 17, ISOFORM A channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0037220|UniProtKB=Q95RB1 Q95RB1 Dmel\CG14641 PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 PRE-MRNA-SPLICING FACTOR RBM22 pre-mRNA binding#GO:0036002;binding#GO:0005488;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0038358|UniProtKB=Q9VF41 Q9VF41 Ttc26 PTHR14781:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 56 INTRAFLAGELLAR TRANSPORT PROTEIN 56 protein-containing complex binding#GO:0044877;binding#GO:0005488 microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;intraciliary transport involved in cilium assembly#GO:0035735;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810 ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0265297|UniProtKB=P21187 P21187 pAbp PTHR24012:SF935 RNA BINDING PROTEIN LD36772P-RELATED single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;poly(A) binding#GO:0008143;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;cytosol#GO:0005829;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0264978|UniProtKB=Q24179 Q24179 Slh PTHR11679:SF2 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;syntaxin binding#GO:0019905;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0036602|UniProtKB=Q9VV26 Q9VV26 Dmel\CG13042 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0000157|UniProtKB=P20009 P20009 Dll PTHR24327:SF81 HOMEOBOX PROTEIN HOMEOTIC PROTEIN DISTAL-LESS-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0259789|UniProtKB=Q9VWC6 Q9VWC6 zld PTHR24393:SF71 ZINC FINGER PROTEIN TRANSCRIPTION FACTOR ZELDA transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0034200|UniProtKB=Q7K533 Q7K533 Gbp2 PTHR10545:SF29 DIAMINE N-ACETYLTRANSFERASE GH14572P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0034578|UniProtKB=Q9W2M9 Q9W2M9 Dmel\CG15653 PTHR47148:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 chaperone#PC00072 DROME|FlyBase=FBgn0264741|UniProtKB=Q0KI22 Q0KI22 BcDNA:AT03227 PTHR12499:SF30 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN nervous system process#GO:0050877;neuromuscular process#GO:0050905;system process#GO:0003008;multicellular organismal process#GO:0032501 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038874|UniProtKB=Q9VDC4 Q9VDC4 ETHR PTHR24243:SF233 G-PROTEIN COUPLED RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0036663|UniProtKB=M9NFH8 M9NFH8 Glts PTHR11938:SF152 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE GLUTAMATE SYNTHASE [NADH] catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;response to nutrient levels#GO:0031667;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;chemical homeostasis#GO:0048878;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;proteinogenic amino acid biosynthetic process#GO:0170038 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037538|UniProtKB=Q9VHX2 Q9VHX2 Dmel\CG3223 PTHR10677:SF25 UBIQUILIN UBIQUITIN-LIKE PROTEIN 7 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0015359|UniProtKB=Q24050 Q24050 Elp5 PTHR15641:SF1 ELONGATOR COMPLEX PROTEIN 5 ELONGATOR COMPLEX PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;elongator holoenzyme complex#GO:0033588;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0036354|UniProtKB=Q9VU65 Q9VU65 Poc1 PTHR44019:SF24 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0033185|UniProtKB=Q1LZ24 Q1LZ24 cliff PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0003525|UniProtKB=P20483 P20483 stg PTHR10828:SF17 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 CDC25-LIKE PROTEIN PHOSPHATASE TWINE-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle process#GO:0090068;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;regulation of reproductive process#GO:2000241;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;regulation of cell cycle G2/M phase transition#GO:1902749;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell cycle G2/M phase transition#GO:0044839;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0029712|UniProtKB=Q9W4J7 Q9W4J7 24639695 PTHR46191:SF2 FAMILY NOT NAMED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0004054|UniProtKB=P09090 P09090 zen2 PTHR45664:SF2 PROTEIN ZERKNUELLT 1-RELATED HOMEOTIC PROTEIN PROBOSCIPEDIA-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0261278|UniProtKB=O61661 O61661 grp PTHR24343:SF540 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE CHK1 histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0051075|UniProtKB=A0A0B4K6I6 A0A0B4K6I6 CT19744 PTHR11699:SF269 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL-LIKE PROTEIN oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;catabolic process#GO:0009056;aldehyde catabolic process#GO:0046185 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 DROME|FlyBase=FBgn0266064|UniProtKB=Q9VFC8 Q9VFC8 Glys PTHR10176:SF3 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0263832|UniProtKB=Q9VZJ3 Q9VZJ3 Rcd5 PTHR13233:SF0 MICROSPHERULE PROTEIN 1 MICROSPHERULE PROTEIN 1 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785 DROME|FlyBase=FBgn0036019|UniProtKB=Q9VT20 Q9VT20 Or67b PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034626|UniProtKB=Q9W2H1 Q9W2H1 bisc PTHR21016:SF1 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of Notch signaling pathway#GO:0045747;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;positive regulation of signal transduction#GO:0009967;programmed cell death#GO:0012501;apoptotic signaling pathway#GO:0097190;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0003733|UniProtKB=P18475 P18475 tor PTHR24416:SF620 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TORSO protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036254|UniProtKB=Q9VTU0 Q9VTU0 CG5645 PTHR14490:SF5 ZINC FINGER, ZZ TYPE PROTEIN KRI1 HOMOLOG cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DROME|FlyBase=FBgn0259982|UniProtKB=Q9VJP9 Q9VJP9 Uxt PTHR13345:SF15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 PROTEIN UXT transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0032791|UniProtKB=Q9VIV5 Q9VIV5 Dmel\CG18094 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 ACYL-COENZYME A DIPHOSPHATASE NUDT19 DROME|FlyBase=FBgn0019830|UniProtKB=Q9VQG4 Q9VQG4 colt PTHR45624:SF4 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED CONGESTED-LIKE TRACHEA PROTEIN-RELATED quaternary ammonium group transmembrane transporter activity#GO:0015651;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;mitochondrial transport#GO:0006839;transport#GO:0006810;intracellular transport#GO:0046907;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 DROME|FlyBase=FBgn0034138|UniProtKB=Q7JZW2 Q7JZW2 RpS15 PTHR11880:SF2 RIBOSOMAL PROTEIN S19P FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US19 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 DROME|FlyBase=FBgn0038505|UniProtKB=Q9VEK5 Q9VEK5 Dmel\CG17283 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 aspartic protease#PC00053;protease#PC00190 DROME|FlyBase=FBgn0032258|UniProtKB=Q95TN4 Q95TN4 Cog4 PTHR24016:SF21 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular component organization#GO:0016043;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0030242|UniProtKB=Q9VZ61 Q9VZ61 sofe PTHR19321:SF57 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED FASCETTO-RELATED microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;organelle assembly#GO:0070925;nuclear division#GO:0000280;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0034118|UniProtKB=Q7JXF5 Q7JXF5 Nup62 PTHR12084:SF0 NUCLEAR PORE GLYCOPROTEIN P62-RELATED NUCLEAR PORE GLYCOPROTEIN P62 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 transporter#PC00227 DROME|FlyBase=FBgn0031693|UniProtKB=Q9VMS9 Q9VMS9 Cyp4ac1 PTHR24291:SF105 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4P1-RELATED oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 DROME|FlyBase=FBgn0260756|UniProtKB=E1JHX0 E1JHX0 Dmel\CG42554 PTHR14964:SF2 NUCLEAR RECEPTOR BINDING FACTOR 2 NUCLEAR RECEPTOR-BINDING FACTOR 2 cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0037102|UniProtKB=Q9VP13 Q9VP13 CRIF PTHR31761:SF1 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP1 LARGE RIBOSOMAL SUBUNIT PROTEIN ML64 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0039726|UniProtKB=Q9VAD4 Q9VAD4 eIF2Balpha PTHR45860:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT ALPHA translation initiation factor#PC00224 DROME|FlyBase=FBgn0036501|UniProtKB=Q9VUN8 Q9VUN8 Dmel\CG7272 PTHR10791:SF5 RAG1-ACTIVATING PROTEIN 1 SUGAR TRANSPORTER SWEET sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036111|UniProtKB=Q7JVG2 Q7JVG2 Aps PTHR12629:SF0 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 phosphatase#PC00181 DROME|FlyBase=FBgn0036512|UniProtKB=Q9VUR0 Q9VUR0 Ufsp2 PTHR48153:SF6 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 2 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0017566|UniProtKB=Q94511 Q94511 ND-75 PTHR11615:SF377 NITRATE, FORMATE, IRON DEHYDROGENASE NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 DROME|FlyBase=FBgn0040963|UniProtKB=Q9VLG0 Q9VLG0 Dmel\CG18662 PTHR12258:SF5 JANUS-A/JANUS-B SEX-REGULATED PROTEIN JANUS-A-RELATED catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039773|UniProtKB=Q9VA71 Q9VA71 Q9VA71 PTHR12947:SF22 AMSH-LIKE PROTEASE FI19924P1 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824 late endosome to vacuole transport#GO:0045324;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907 vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0001112|UniProtKB=P18173 P18173 Gld PTHR11552:SF217 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE GLUCOSE DEHYDROGENASE [FAD, QUINONE] catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0025936|UniProtKB=Q9V4E5 Q9V4E5 Eph PTHR24416:SF539 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0028662|UniProtKB=Q9VFE3 Q9VFE3 VhaPPA1-1 PTHR10263:SF18 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 21 KDA PROTEOLIPID SUBUNIT C'' cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0028984|UniProtKB=Q9VFC2 Q9VFC2 Spn88Ea PTHR11461:SF278 SERINE PROTEASE INHIBITOR, SERPIN SERINE PROTEASE INHIBITOR 88EA cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0031314|UniProtKB=Q9VPY0 Q9VPY0 IntS14 PTHR13532:SF3 FAMILY NOT NAMED INTEGRATOR COMPLEX SUBUNIT 14 DROME|FlyBase=FBgn0286075|UniProtKB=Q9VG84 Q9VG84 DNAlig3 PTHR45674:SF20 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 3 ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA ligase#PC00012 DROME|FlyBase=FBgn0039045|UniProtKB=Q9VCR7 Q9VCR7 Ctns PTHR13131:SF14 CYSTINOSIN CYSTINOSIN amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0038275|UniProtKB=Q9VFE6 Q9VFE6 CG3817 PTHR13245:SF14 RRP15-LIKE PROTEIN RRP15-LIKE PROTEIN metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 DROME|FlyBase=FBgn0036817|UniProtKB=M9NDV6 M9NDV6 Dmel\CG6865 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0037465|UniProtKB=Q9VI53 Q9VI53 Dmel\CG1105 PTHR11188:SF17 ARRESTIN DOMAIN CONTAINING PROTEIN LD44267P cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0033834|UniProtKB=A1Z9C4 A1Z9C4 Dmel\CG4744 PTHR13992:SF39 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR SMRTER, ISOFORM G regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0015765|UniProtKB=O62618 O62618 p38a PTHR24055:SF615 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE P38A-RELATED catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;FGF signaling pathway#P00021>p38#P00644;TGF-beta signaling pathway#P00052>P38#P01275;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Parkinson disease#P00049>p38 MAPK#P01212 DROME|FlyBase=FBgn0036896|UniProtKB=Q9VW24 Q9VW24 wnd PTHR23257:SF1008 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0259189|UniProtKB=B7Z0X5 B7Z0X5 Ir7e PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0030973|UniProtKB=Q9VWN5 Q9VWN5 mindy3 PTHR12473:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-3 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005 DROME|FlyBase=FBgn0262685|UniProtKB=Q9VYY5 Q9VYY5 CG15194 PTHR11003:SF359 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0036198|UniProtKB=Q9VTM6 Q9VTM6 crim PTHR33562:SF28 ATILLA, ISOFORM B-RELATED-RELATED UPAR_LY6 DOMAIN-CONTAINING PROTEIN CRIM DROME|FlyBase=FBgn0024963|UniProtKB=Q94900 Q94900 GluClalpha PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0038412|UniProtKB=Q9VEX1 Q9VEX1 Zip89B PTHR11040:SF203 ZINC/IRON TRANSPORTER FI18611P1-RELATED transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0050094|UniProtKB=Q7JR99 Q7JR99 Dmel\CG30094 PTHR14677:SF39 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED RE31204P modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;localization#GO:0051179;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein targeting#GO:0006605;catabolic process#GO:0009056;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;proteasomal protein catabolic process#GO:0010498;establishment of protein localization to endoplasmic reticulum#GO:0072599 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0040687|UniProtKB=Q9VN06 Q9VN06 Dmel\CG14645 PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0034182|UniProtKB=Q5U179 Q5U179 SmydA-7 PTHR46455:SF6 SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A RE22408P-RELATED intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0013995|UniProtKB=Q9VDG5 Q9VDG5 Calx PTHR11878:SF80 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER CALX calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0037176|UniProtKB=B7Z0A0 B7Z0A0 Dmel\CG14456 PTHR20898:SF1 DAEDALUS ON 3-RELATED-RELATED MD-2-RELATED LIPID-RECOGNITION DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0033712|UniProtKB=A0A384ZD34 A0A384ZD34 mIF3 PTHR10938:SF9 TRANSLATION INITIATION FACTOR IF-3 TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translation initiation factor#PC00224 DROME|FlyBase=FBgn0031060|UniProtKB=Q9VWD6 Q9VWD6 Tcs4 PTHR11735:SF6 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0034360|UniProtKB=Q7K157 Q7K157 Dmel\CG10927 PTHR11079:SF156 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE-34 DEAMINASE REGULATORY SUBUNIT ADAT3 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 DROME|FlyBase=FBgn0034909|UniProtKB=Q8MLQ7 Q8MLQ7 pippin PTHR48021:SF7 FAMILY NOT NAMED RH09188P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037828|UniProtKB=Q9VGX9 Q9VGX9 tomboy20 PTHR12430:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20 mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;mitochondrial transport#GO:0006839;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane translocase complex#GO:0005742;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0038805|UniProtKB=Q86BR8 Q86BR8 TFAM PTHR48112:SF41 HIGH MOBILITY GROUP PROTEIN DSP1 MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;nucleus#GO:0005634 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0030460|UniProtKB=Q9VYF8 Q9VYF8 Coq5 PTHR43591:SF116 METHYLTRANSFERASE 2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 transferase#PC00220;methyltransferase#PC00155 DROME|FlyBase=FBgn0024230|UniProtKB=P25722 P25722 Hs2st PTHR12129:SF17 HEPARAN SULFATE 2-O-SULFOTRANSFERASE HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034829|UniProtKB=Q9W1T9 Q9W1T9 Ctr9L PTHR14027:SF2 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0011288|UniProtKB=P36975 P36975 Snap25 PTHR19305:SF14 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN-RELATED molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484 trans-synaptic signaling#GO:0099537;signal release#GO:0023061;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;synaptic vesicle membrane organization#GO:0048499;membrane fusion#GO:0061025;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;cellular localization#GO:0051641;secretion by cell#GO:0032940;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;export from cell#GO:0140352;signaling#GO:0023052;regulated exocytosis#GO:0045055;vesicle fusion to plasma membrane#GO:0099500;exocytic process#GO:0140029;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;neurotransmitter transport#GO:0006836 SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Synaptic vesicle trafficking#P05734>SNAP-25#P05778;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049 DROME|FlyBase=FBgn0010317|UniProtKB=Q9VZP3 Q9VZP3 CycJ PTHR10177:SF210 CYCLINS CYCLIN J, ISOFORM A enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 DROME|FlyBase=FBgn0029867|UniProtKB=Q9W403 Q9W403 Dmel\CG3847 PTHR24384:SF189 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032858|UniProtKB=Q9VIM6 Q9VIM6 Dmel\CG10949 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0086445|UniProtKB=Q9VIZ2 Q9VIZ2 l(2)37Cd PTHR13230:SF5 GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA transcription#GO:0009303;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 protein-containing complex#GO:0032991;transcription factor TFIIIC complex#GO:0000127;transcription regulator complex#GO:0005667 general transcription factor#PC00259 DROME|FlyBase=FBgn0035390|UniProtKB=Q9VZW1 Q9VZW1 scramb2 PTHR23248:SF9 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215 cellular process#GO:0009987;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0051109|UniProtKB=Q9VBY9 Q9VBY9 Dmel\CG31109 PTHR39942:SF1 BCDNA.LD26519-RELATED BCDNA.LD26519-RELATED DROME|FlyBase=FBgn0031952|UniProtKB=Q9VLW7 Q9VLW7 Cdc14 PTHR23339:SF129 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE CELL DIVISION CYCLE 14, ISOFORM A catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of cell cycle#GO:0051726;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;cilium organization#GO:0044782;regulation of mitotic cell cycle phase transition#GO:1901990;microtubule cytoskeleton organization#GO:0000226;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell projection assembly#GO:0030031;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cell cycle#GO:0045787;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 protein phosphatase#PC00195;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0050480|UniProtKB=A1Z9U0 A1Z9U0 Dmel\CG30480 PTHR23202:SF119 WASP INTERACTING PROTEIN-RELATED FI03313P cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0011554|UniProtKB=P42279 P42279 etaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0040066|UniProtKB=Q9V3J8 Q9V3J8 wds PTHR22847:SF751 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase II#GO:0006366;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;Set1C/COMPASS complex#GO:0048188;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;NSL complex#GO:0044545;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654 DROME|FlyBase=FBgn0037941|UniProtKB=Q9VGJ0 Q9VGJ0 Dmel\CG12594 PTHR22906:SF43 PROPERDIN PROPERDIN DROME|FlyBase=FBgn0034844|UniProtKB=Q9W1S3 Q9W1S3 Dmel\CG9861 PTHR41967:SF6 FI19406P1-RELATED FI19406P1-RELATED DROME|FlyBase=FBgn0037485|UniProtKB=A0A1Z1CGZ4 A0A1Z1CGZ4 Dmel\CG14606 PTHR48021:SF33 FAMILY NOT NAMED AT22075P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0004102|UniProtKB=P22810 P22810 oc PTHR45793:SF5 HOMEOBOX PROTEIN HOMEOTIC PROTEIN OCELLILESS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cell fate specification#GO:0001708;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0052268|UniProtKB=Q9VZQ4 Q9VZQ4 Drsl6 PTHR33147:SF98 DEFENSIN-LIKE PROTEIN 1 DRO1 PROTEIN-RELATED defense response#GO:0006952;response to stimulus#GO:0050896;response to stress#GO:0006950 antimicrobial response protein#PC00051 DROME|FlyBase=FBgn0035254|UniProtKB=Q9W0A9 Q9W0A9 Dmel\CG7974 PTHR13486:SF2 TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER SPLICING FACTOR C9ORF78 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038425|UniProtKB=Q9VEV6 Q9VEV6 Dmel\CG14881 PTHR43437:SF3 HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0030634|UniProtKB=Q9VXV9 Q9VXV9 CG9164 PTHR45964:SF5 WSCD FAMILY MEMBER CG9164 WSCD FAMILY MEMBER CG9164 DROME|FlyBase=FBgn0038611|UniProtKB=Q9VE79 Q9VE79 Dmel\CG14309 PTHR46145:SF4 HEPARANASE HEPARANASE glycosidase#PC00110 DROME|FlyBase=FBgn0035571|UniProtKB=Q9VZ88 Q9VZ88 cg12493 PTHR10910:SF62 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN AT07585P-RELATED tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 RNA biosynthetic process#GO:0032774;adenosine to inosine editing#GO:0006382;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030394|UniProtKB=Q9VYM5 Q9VYM5 Cpr11A PTHR10380:SF228 CUTICLE PROTEIN CUTICULAR PROTEIN 11A-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0034073|UniProtKB=A1ZA92 A1ZA92 Nol9 PTHR12755:SF3 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9 nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0005585|UniProtKB=P29413 P29413 Calr PTHR11073:SF2 CALRETICULIN AND CALNEXIN CALRETICULIN ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to chemical#GO:0042221;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 chaperone#PC00072 DROME|FlyBase=FBgn0023214|UniProtKB=Q7K119 Q7K119 edl PTHR11849:SF187 ETS ETS-DOMAIN LACKING DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0260945|UniProtKB=Q8MQJ7 Q8MQJ7 Atg1 PTHR24348:SF79 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED AUTOPHAGY-RELATED 1, ISOFORM B catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;axon extension#GO:0048675;cellular component assembly#GO:0022607;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron differentiation#GO:0030182;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cell projection morphogenesis#GO:0048858;cell growth#GO:0016049;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;regulation of autophagy#GO:0010506;cell development#GO:0048468;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;process utilizing autophagic mechanism#GO:0061919;neuron development#GO:0048666;axonogenesis#GO:0007409;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;regulation of metabolic process#GO:0019222;axon development#GO:0061564;reticulophagy#GO:0061709;response to nutrient levels#GO:0031667;plasma membrane bounded cell projection organization#GO:0120036;macroautophagy#GO:0016236;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;autophagy of mitochondrion#GO:0000422;neurogenesis#GO:0022008;regulation of catabolic process#GO:0009894;cellular developmental process#GO:0048869;developmental growth#GO:0048589;mitophagy#GO:0000423;response to starvation#GO:0042594;developmental cell growth#GO:0048588;piecemeal microautophagy of the nucleus#GO:0034727;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;organelle assembly#GO:0070925;system development#GO:0048731;vacuole organization#GO:0007033;anatomical structure development#GO:0048856 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;autophagosome#GO:0005776;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0027548|UniProtKB=Q7KMJ6 Q7KMJ6 nito PTHR23189:SF137 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN SPENITO nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0036751|UniProtKB=Q9VVK4 Q9VVK4 Adgf-B PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;adenosine deaminase activity#GO:0004000;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 purine nucleoside metabolic process#GO:0042278;purine-containing compound biosynthetic process#GO:0072522;nucleoside catabolic process#GO:0009164;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine nucleobase metabolic process#GO:0006144;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;extracellular region#GO:0005576 deaminase#PC00088 DROME|FlyBase=FBgn0037548|UniProtKB=Q9VHV9 Q9VHV9 Dmel\CG7900 PTHR43372:SF3 FATTY-ACID AMIDE HYDROLASE AT07710P-RELATED hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|Gene_ORFName=Dmel_CG46509|UniProtKB=A0ACD4DAW5 A0ACD4DAW5 CG46509 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0263251|UniProtKB=Q9VT75 Q9VT75 vnc PTHR23091:SF4 N-TERMINAL ACETYLTRANSFERASE N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 acetyltransferase#PC00038 DROME|FlyBase=FBgn0035856|UniProtKB=Q8SZ49 Q8SZ49 Dmel\CG13679 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0085693|UniProtKB=A8QI32 A8QI32 Dmel\CG41562 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0036030|UniProtKB=Q9VT33 Q9VT33 Prps PTHR10210:SF123 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0052179|UniProtKB=Q9VVJ6 Q9VVJ6 Krn PTHR12332:SF1 KEREN-RELATED KEREN-RELATED cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 DROME|FlyBase=FBgn0267330|UniProtKB=O76767 O76767 KdelR PTHR10585:SF14 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR signal sequence receptor activity#GO:0005048 macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;intracellular protein localization#GO:0008104 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cis-Golgi network#GO:0005801;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0260971|UniProtKB=E1JJG7 E1JJG7 CG32771 PTHR11003:SF257 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0011283|UniProtKB=P54195 P54195 Obp28a PTHR11857:SF42 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 19D-RELATED sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0053965|UniProtKB=Q2MGL9 Q2MGL9 Dmel\CG33965 PTHR10174:SF216 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN-RELATED ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0031968|UniProtKB=Q9VLU9 Q9VLU9 Dmel\CG7231 PTHR21184:SF6 MENORIN (DENDRITIC BRANCHING PROTEIN) MENORIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0264959|UniProtKB=Q9V9J3 Q9V9J3 Src42A PTHR24418:SF373 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRC42A catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715 cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167;developmental process#GO:0032502;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940 DROME|FlyBase=FBgn0026174|UniProtKB=Q9VWC5 Q9VWC5 SkpD PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0027108|UniProtKB=Q9V427 Q9V427 Inx2 PTHR11893:SF41 INNEXIN INNEXIN INX2 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell communication#GO:0007154;response to external stimulus#GO:0009605;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to radiation#GO:0009314;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 gap junction#PC00105 DROME|FlyBase=FBgn0037301|UniProtKB=Q95U54 Q95U54 Mms19 PTHR12891:SF0 DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19 MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037134|UniProtKB=Q9VNX9 Q9VNX9 BcDNA:LD29166 PTHR21845:SF2 TRANSMEMBRANE ANCHOR PROTEIN 1 MATRIX-REMODELING-ASSOCIATED PROTEIN 7 DROME|FlyBase=FBgn0046685|UniProtKB=P83097 P83097 Wsck PTHR24418:SF448 TYROSINE-PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE WSCK-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 DROME|FlyBase=FBgn0038058|UniProtKB=Q9VG59 Q9VG59 Dmel\CG5608 PTHR16023:SF0 TAX1 BINDING PROTEIN-RELATED PROTEIN VAC14 HOMOLOG phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;transferase complex#GO:1990234;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039596|UniProtKB=Q8MYY6 Q8MYY6 pgant13 PTHR11675:SF128 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 13-RELATED polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0034346|UniProtKB=A1ZB84 A1ZB84 PIG-O PTHR23071:SF1 PHOSPHATIDYLINOSITOL GLYCAN GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3, CATALYTIC SUBUNIT phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0039434|UniProtKB=Q9VBE2 Q9VBE2 TwdlM PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 DROME|FlyBase=FBgn0037384|UniProtKB=Q9VNJ0 Q9VNJ0 dgrn PTHR23041:SF83 RING FINGER DOMAIN-CONTAINING DEGRINGOLADE, ISOFORM A-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;DNA repair#GO:0006281;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA damage response#GO:0006974;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0002609|UniProtKB=Q01068 Q01068 E(spl)m3-HLH PTHR10985:SF12 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED ENHANCER OF SPLIT M3 PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 DROME|FlyBase=FBgn0040022|UniProtKB=Q5LJZ2 Q5LJZ2 Set1 PTHR45814:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0032746|UniProtKB=Q9VJ11 Q9VJ11 anon-37B-2 PTHR20917:SF1 PNAS-RELATED CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 DROME|FlyBase=FBgn0083950|UniProtKB=Q0KI85 Q0KI85 side-VI PTHR23278:SF34 SIDESTEP PROTEIN SIDESTEP VI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0033933|UniProtKB=A1Z9Q9 A1Z9Q9 Dmel\CG10104 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 aspartic protease#PC00053;protease#PC00190 DROME|FlyBase=FBgn0033502|UniProtKB=Q7K2R1 Q7K2R1 Dmel\CG12910 PTHR21461:SF1 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0261526|UniProtKB=B7TB45 B7TB45 NT1 PTHR23199:SF12 NEUROTROPHIN 1-RELATED NEUROTROPHIN 1 DROME|FlyBase=FBgn0028668|UniProtKB=Q9VTI6 Q9VTI6 Vha16-2 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0000723|UniProtKB=P18106 P18106 FER PTHR24418:SF418 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FER catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715 response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 DROME|FlyBase=FBgn0037911|UniProtKB=Q9VGM4 Q9VGM4 Dmel\CG10898 PTHR22769:SF56 MUTT/NUDIX HYDROLASE 8-OXO-DGDP PHOSPHATASE NUDT18 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787 hydrolase#PC00121 DROME|FlyBase=FBgn0024179|UniProtKB=M9PE88 M9PE88 wit PTHR23255:SF100 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transforming growth factor beta receptor activity#GO:0005024 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 BMP/activin signaling pathway-drosophila#P06211>TGFbetaR II#P06255;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;MYO signaling pathway#P06215>WIT#P06316;GBB signaling pathway#P06214>WIT#P06306 DROME|FlyBase=FBgn0083969|UniProtKB=Q8IMK1 Q8IMK1 CG31035 PTHR14221:SF72 WD REPEAT DOMAIN 44 WD REPEAT-CONTAINING PROTEIN 44 organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 DROME|FlyBase=FBgn0053771|UniProtKB=Q4ABH5 Q4ABH5 Dmel\CG33771 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0033726|UniProtKB=A1Z8Y8 A1Z8Y8 Cpr49Ad PTHR10380:SF200 CUTICLE PROTEIN CUTICULAR PROTEIN 49AB-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0033052|UniProtKB=A1Z6J2 A1Z6J2 SCAP PTHR46378:SF1 STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN regulation of lipid biosynthetic process#GO:0046890;regulation of steroid biosynthetic process#GO:0050810;biological regulation#GO:0065007;SREBP signaling pathway#GO:0032933;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of lipid metabolic process#GO:0019216;cellular response to stress#GO:0033554 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0028717|UniProtKB=A0A0B4LHY5 A0A0B4LHY5 Lnk PTHR10872:SF2 SH2B ADAPTER PROTEIN LNK, ISOFORM D signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038482|UniProtKB=Q9VEM7 Q9VEM7 Dmel\CG4053 PTHR24260:SF138 AT07769P-RELATED IP10340P-RELATED DROME|FlyBase=FBgn0050273|UniProtKB=Q8MME9 Q8MME9 CG13515 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;ion binding#GO:0043167;transition metal ion binding#GO:0046914 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031895|UniProtKB=Q9VM36 Q9VM36 Dmel\CG4497 PTHR22227:SF6 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 PROTEIN FAM122B ISOFORM X1 protein serine/threonine phosphatase inhibitor activity#GO:0004865;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208 positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DROME|FlyBase=FBgn0036760|UniProtKB=Q9VVL5 Q9VVL5 Dmel\CG5567 PTHR19288:SF93 4-NITROPHENYLPHOSPHATASE-RELATED FI11325P-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0039265|UniProtKB=Q8SWX6 Q8SWX6 Dmel\CG11790 PTHR19991:SF2 L 2 01289 GH08893P DROME|FlyBase=FBgn0051361|UniProtKB=Q9VGD3 Q9VGD3 dpr17 PTHR23279:SF21 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 11, ISOFORM B-RELATED cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0030664|UniProtKB=Q9VXS5 Q9VXS5 Dmel\CG8119 PTHR12243:SF67 MADF DOMAIN TRANSCRIPTION FACTOR COREPRESSOR OF PANGOLIN, ISOFORM A-RELATED biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0039592|UniProtKB=Q9VAU3 Q9VAU3 LP23408p PTHR13966:SF19 ENDONUCLEASE RELATED DNA_RNA NON-SPECIFIC ENDONUCLEASE DOMAIN-CONTAINING PROTEIN-RELATED nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on DNA#GO:0140097 primary metabolic process#GO:0044238;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;catabolic process#GO:0009056;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0263757|UniProtKB=Q9VEA5 Q9VEA5 Polr2D PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 binding#GO:0005488;translation initiation factor binding#GO:0031369;protein binding#GO:0005515 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 DROME|FlyBase=FBgn0011555|UniProtKB=P42278 P42278 thetaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0041585|UniProtKB=Q9U6B8 Q9U6B8 Orai PTHR31501:SF7 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 ion channel#PC00133 DROME|FlyBase=FBgn0010226|UniProtKB=P41043 P41043 GstS1 PTHR11571:SF274 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE S1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790 transferase#PC00220 DROME|FlyBase=FBgn0035676|UniProtKB=Q9VRT8 Q9VRT8 ssp6 PTHR15963:SF5 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED SHORT SPINDLE 6, ISOFORM A DROME|FlyBase=FBgn0038678|UniProtKB=Q9VE04 Q9VE04 mRpL55 PTHR34095:SF1 39S RIBOSOMAL PROTEIN L55, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML55 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 DROME|FlyBase=FBgn0260767|UniProtKB=Q9W219 Q9W219 CG13512 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0034856|UniProtKB=Q9W1R0 Q9W1R0 yellow-d2 PTHR10009:SF7 PROTEIN YELLOW-RELATED GH10609P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0031391|UniProtKB=Q9VQ77 Q9VQ77 11723 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0263102|UniProtKB=A0A6M3Q7H0 A0A6M3Q7H0 psq PTHR23110:SF102 BTB DOMAIN TRANSCRIPTION FACTOR PIPSQUEAK, ISOFORM O regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0000567|UniProtKB=P11536 P11536 Eip74EF PTHR11849:SF191 ETS ECDYSONE-INDUCED PROTEIN 74EF ISOFORM B transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 DROME|FlyBase=FBgn0037580|UniProtKB=Q9VHR8 Q9VHR8 DppIII PTHR23422:SF11 DIPEPTIDYL PEPTIDASE III-RELATED DIPEPTIDYL PEPTIDASE 3 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0004575|UniProtKB=Q24546 Q24546 Syn PTHR10841:SF17 SYNAPSIN SYNAPSIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093 cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 DROME|FlyBase=FBgn0030181|UniProtKB=A8JUP5 A8JUP5 Dmel\CG12645 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED transition metal ion binding#GO:0046914;zinc ion binding#GO:0008270;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0010380|UniProtKB=Q24253 Q24253 AP-1-2beta PTHR11134:SF33 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP COMPLEX SUBUNIT BETA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0031700|UniProtKB=Q9VMR9 Q9VMR9 BcDNA:RH62365 PTHR10029:SF10 ACYLPHOSPHATASE ACYLPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 DROME|FlyBase=FBgn0064115|UniProtKB=Q86BL4 Q86BL4 GatC PTHR15004:SF0 GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL translation#GO:0006412;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0013759|UniProtKB=Q24210 Q24210 CASK PTHR23122:SF7 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PERIPHERAL PLASMA MEMBRANE PROTEIN CASK signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;macromolecule localization#GO:0033036;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104;regulation of transport#GO:0051049;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>CASK#P01232;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847 DROME|FlyBase=FBgn0027621|UniProtKB=Q9VWH7 Q9VWH7 Pfrx PTHR10606:SF44 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphatase activity#GO:0016791;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578;sugar-phosphatase activity#GO:0050308;hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121 DROME|FlyBase=FBgn0259241|UniProtKB=Q9VZ43 Q9VZ43 vex PTHR20920:SF5 RPE-SPONDIN VEXED, ISOFORM B DROME|FlyBase=FBgn0037902|UniProtKB=Q9VGN6 Q9VGN6 Dmel\CG5281 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED RH69884P membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0039439|UniProtKB=Q9VBD7 Q9VBD7 TwdlK PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0051106|UniProtKB=Q8IMT7 Q8IMT7 Dmel\CG31106 PTHR23511:SF37 SYNAPTIC VESICLE GLYCOPROTEIN 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0026088|UniProtKB=O97420 O97420 CG14818 PTHR34344:SF1 UPF0184 PROTEIN C9ORF16 BUBLIN COILED-COIL PROTEIN cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;intermediate filament bundle assembly#GO:0045110;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 DROME|FlyBase=FBgn0053725|UniProtKB=Q4ABI9 Q4ABI9 Dmel\CG33725 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0038766|UniProtKB=Q9VDQ5 Q9VDQ5 Dmel\CG4854 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0000316|UniProtKB=P39205 P39205 cin PTHR10192:SF33 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN GEPHYRIN transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;neuromuscular junction development#GO:0007528;metabolic process#GO:0008152;membrane organization#GO:0061024;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;macromolecule localization#GO:0033036;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;receptor clustering#GO:0043113;synapse organization#GO:0050808;localization within membrane#GO:0051668;cell junction organization#GO:0034330;postsynapse organization#GO:0099173;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein localization to membrane#GO:0072657 intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;postsynaptic membrane#GO:0045211;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron projection#GO:0043005;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020 DROME|FlyBase=FBgn0284244|UniProtKB=Q9VK10 Q9VK10 l(2)k05911 PTHR24256:SF580 TRYPTASE-RELATED PHENOLOXIDASE-ACTIVATING FACTOR 2 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0032409|UniProtKB=Q9VKB2 Q9VKB2 Ced-12 PTHR12771:SF74 ENGULFMENT AND CELL MOTILITY CED-12 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037512|UniProtKB=Q9VI05 Q9VI05 Dmel\CG2616 PTHR45760:SF2 FI19922P1-RELATED FI19922P1-RELATED intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0010282|UniProtKB=Q05913 Q05913 TfIIFalpha PTHR13011:SF0 TFIIF-ALPHA GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 binding#GO:0005488;transcription factor binding#GO:0008134;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFalpha#P00663;Transcription regulation by bZIP transcription factor#P00055>TFIIFalpha#P01391 DROME|FlyBase=FBgn0026873|UniProtKB=Q9XZT1 Q9XZT1 MED18 PTHR13321:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0038002|UniProtKB=Q9VGB9 Q9VGB9 Dmel\CG12256 PTHR24256:SF562 TRYPTASE-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0024841|UniProtKB=O76454 O76454 Pcd PTHR12599:SF0 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE dehydratase#PC00091;lyase#PC00144 DROME|FlyBase=FBgn0026566|UniProtKB=O97067 O97067 CG1307 PTHR12649:SF11 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE 2-RELATED DROME|FlyBase=FBgn0052274|UniProtKB=Q9VZQ5 Q9VZQ5 Drsl1 PTHR33147:SF98 DEFENSIN-LIKE PROTEIN 1 DRO1 PROTEIN-RELATED defense response#GO:0006952;response to stimulus#GO:0050896;response to stress#GO:0006950 antimicrobial response protein#PC00051 DROME|FlyBase=FBgn0038984|UniProtKB=Q9VCY8 Q9VCY8 AdipoR PTHR20855:SF152 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to chemical stimulus#GO:0070887;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0031738|UniProtKB=Q7JRE1 Q7JRE1 Dmel\CG9171 PTHR47412:SF1 FI01434P-RELATED FI01434P-RELATED DROME|FlyBase=FBgn0032651|UniProtKB=Q9VJC1 Q9VJC1 Oli PTHR19290:SF104 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED GH17679P sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0011834|UniProtKB=Q9VRD0 Q9VRD0 Ser6 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0021995|UniProtKB=Q7JQN4 Q7JQN4 Rs1 PTHR24031:SF706 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX27-RELATED gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0031285|UniProtKB=Q9VPT9 Q9VPT9 Dmel\CG3662 PTHR10962:SF1 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2 binding#GO:0005488;peptide binding#GO:0042277 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0033313|UniProtKB=A1Z7G7 A1Z7G7 Cirl PTHR12011:SF347 ADHESION G-PROTEIN COUPLED RECEPTOR LATROPHILIN CIRL cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0001091|UniProtKB=P07486 P07486 Gapdh1 PTHR10836:SF76 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 DROME|FlyBase=FBgn0046247|UniProtKB=Q0KI06 Q0KI06 Dmel\CG5938 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0029861|UniProtKB=Q9W410 Q9W410 PF1 PTHR46309:SF28 PHD FINGER PROTEIN 12 PHD FINGER PROTEIN 12 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0034479|UniProtKB=Q7K3M6 Q7K3M6 CG8654-RA PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034400|UniProtKB=A1ZBE8 A1ZBE8 CG15099 PTHR14042:SF24 DOPEY-RELATED PROTEIN DOP1 HOMOLOG establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;retrograde transport, vesicle recycling within Golgi#GO:0000301;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;Golgi apparatus#GO:0005794 DROME|FlyBase=FBgn0030466|UniProtKB=Q7KV24 Q7KV24 Remo PTHR45930:SF4 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN REMOULADE cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031268|UniProtKB=Q9VPR7 Q9VPR7 cold PTHR20914:SF9 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 UPAR_LY6 DOMAIN-CONTAINING PROTEIN COLD scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036741|UniProtKB=M9PFK5 M9PFK5 anchor PTHR22829:SF5 DEP DOMAIN PROTEIN LYSOSOMAL CHOLESTEROL SIGNALING PROTEIN regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of BMP signaling pathway#GO:0030510;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0050487|UniProtKB=Q6NN84 Q6NN84 NEST:bs16h04 PTHR31383:SF2 OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1 OXIDATIVE STRESS-RESPONSIVE SERINE-RICH PROTEIN 1 DROME|FlyBase=FBgn0260793|UniProtKB=A0A0B4KFU1 A0A0B4KFU1 2mit PTHR45617:SF167 LEUCINE RICH REPEAT FAMILY PROTEIN 2MIT, ISOFORM B scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0004852|UniProtKB=Q9VW60 Q9VW60 Ac76E PTHR45627:SF35 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 2 catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016 regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cyclic purine nucleotide metabolic process#GO:0052652 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0051191|UniProtKB=A8JR57 A8JR57 CG17277 PTHR21010:SF3 AGAP001581-PA DAXX DROME|FlyBase=FBgn0045482|UniProtKB=Q8MLS6 Q8MLS6 Gr59b PTHR21143:SF132 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 33A-RELATED dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;neuron projection#GO:0043005;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031959|UniProtKB=Q9VLV7 Q9VLV7 spz3 PTHR23199:SF13 NEUROTROPHIN 1-RELATED PROTEIN SPAETZLE 3 signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;central nervous system development#GO:0007417;response to stimulus#GO:0050896;developmental process#GO:0032502;response to external stimulus#GO:0009605;anatomical structure formation involved in morphogenesis#GO:0048646;defense response#GO:0006952;multicellular organism development#GO:0007275;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;nervous system development#GO:0007399;response to other organism#GO:0051707;multicellular organismal process#GO:0032501;defense response to other organism#GO:0098542 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030417|UniProtKB=Q9VYJ8 Q9VYJ8 Dmel\CG15725 PTHR46105:SF5 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0013277|UniProtKB=Q8INI8 Q8INI8 Hsp70Ba PTHR19375:SF518 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN AA-RELATED hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein refolding#GO:0042026;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 DROME|FlyBase=FBgn0036726|UniProtKB=Q9VVH3 Q9VVH3 QIL1 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 mitochondrion organization#GO:0007005;membrane organization#GO:0061024;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;cellular component organization or biogenesis#GO:0071840 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle membrane contact site#GO:0044232;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0045471|UniProtKB=Q8IN58 Q8IN58 Gr92a PTHR16189:SF0 TRANSMEMBRANE PROTEIN 104-RELATED SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 12-RELATED DROME|FlyBase=FBgn0033357|UniProtKB=Q7K036 Q7K036 Tom7 PTHR46722:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 primary active transporter#PC00068 DROME|FlyBase=FBgn0033893|UniProtKB=Q4V6I0 Q4V6I0 CG18371-RA PTHR10029:SF3 ACYLPHOSPHATASE ACYLPHOSPHATASE-1 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0033716|UniProtKB=E1JH43 E1JH43 Den1 PTHR46468:SF1 SENTRIN-SPECIFIC PROTEASE 8 SENTRIN-SPECIFIC PROTEASE 8 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687 protease#PC00190 DROME|FlyBase=FBgn0002562|UniProtKB=P11995 P11995 Lsp1alpha PTHR11511:SF5 LARVAL STORAGE PROTEIN/PHENOLOXIDASE FAT-BODY PROTEIN 1-RELATED DROME|FlyBase=FBgn0051523|UniProtKB=Q95T98 Q95T98 CG9798 PTHR11157:SF162 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0035916|UniProtKB=Q9VSM8 Q9VSM8 GAPsec PTHR22957:SF27 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 13 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0045500|UniProtKB=P84180 P84180 Gr22b PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED cell body#GO:0044297;neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0002535|UniProtKB=P07189 P07189 Lcp4 PTHR10380:SF230 CUTICLE PROTEIN CUTICULAR PROTEIN 47EE-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0031682|UniProtKB=Q9VMU2 Q9VMU2 Dmel\CG5828 PTHR12280:SF35 PANTOTHENATE KINASE 4'-PHOSPHOPANTETHEINE PHOSPHATASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 kinase#PC00137;metabolite interconversion enzyme#PC00262 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 DROME|FlyBase=FBgn0037205|UniProtKB=Q9VNP5 Q9VNP5 BoYb PTHR22655:SF2 ATP-DEPENDENT RNA HELICASE TDRD12-RELATED ATP-DEPENDENT RNA HELICASE TDRD12-RELATED negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;piRNA processing#GO:0034587;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0030672|UniProtKB=Q9VXR5 Q9VXR5 Dmel\CG9281 PTHR19211:SF15 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2 anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 translation elongation factor#PC00222 DROME|FlyBase=FBgn0029857|UniProtKB=Q9W415 Q9W415 wuho PTHR16288:SF0 WD40 REPEAT PROTEIN 4 TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0264975|UniProtKB=P20241 P20241 Nrg PTHR12231:SF256 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN NEUROGLIAN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0259717|UniProtKB=B7YZZ0 B7YZZ0 Dmel\CG42371 PTHR38001:SF1 PROTEIN CEBPZOS PROTEIN CEBPZOS DROME|FlyBase=FBgn0040510|UniProtKB=Q9VK51 Q9VK51 ACXA PTHR45627:SF12 ADENYLATE CYCLASE TYPE 1 ADENYLYL CYCLASE X E-RELATED cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0032487|UniProtKB=Q9VK19 Q9VK19 Ski6 PTHR11953:SF0 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP41 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA catabolic process#GO:0006401;macromolecule catabolic process#GO:0009057;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DROME|FlyBase=FBgn0051524|UniProtKB=Q8IMI2 Q8IMI2 Dmel\CG31524 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;oxidoreductase complex#GO:1990204;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0000394|UniProtKB=Q9W494 Q9W494 cv PTHR12312:SF16 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 SCW signaling pathway#P06216>TSG#P06330;DPP-SCW signaling pathway#P06212>TSG#P06258;BMP/activin signaling pathway-drosophila#P06211>TSG#P06242;DPP signaling pathway#P06213>TSG#P06287 DROME|FlyBase=FBgn0260660|UniProtKB=M9ND55 M9ND55 Mp PTHR24023:SF1129 COLLAGEN ALPHA MULTIPLEXIN, ISOFORM R structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0259817|UniProtKB=B8K3A5 B8K3A5 SteXh:CG42398 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0052072|UniProtKB=Q5JZZ4 Q5JZZ4 Elo68alpha PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0040268|UniProtKB=Q9NG98 Q9NG98 Top3alpha PTHR11390:SF21 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-ALPHA macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 nucleus#GO:0005634;chromosome#GO:0005694;DNA helicase complex#GO:0033202;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0053958|UniProtKB=A1ZB47 A1ZB47 CG5719 PTHR11920:SF504 GUANYLYL CYCLASE GUANYLATE CYCLASE lyase activity#GO:0016829;molecular transducer activity#GO:0060089;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653 enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;cell communication#GO:0007154;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 lyase#PC00144;guanylate cyclase#PC00114 DROME|FlyBase=FBgn0029949|UniProtKB=Q9W3R1 Q9W3R1 Dmel\CG15035 PTHR12320:SF98 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 DROME|FlyBase=FBgn0063649|UniProtKB=A2RVG5 A2RVG5 Dmel\CG6006 PTHR24064:SF547 SOLUTE CARRIER FAMILY 22 MEMBER IP17430P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0037762|UniProtKB=Q9VH58 Q9VH58 eloF PTHR11157:SF116 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0034486|UniProtKB=A1ZBR8 A1ZBR8 Dmel\CG13869 PTHR21398:SF11 AGAP007094-PA HDC15381-RELATED DROME|FlyBase=FBgn0035498|UniProtKB=Q9VZI3 Q9VZI3 Fit1 PTHR16160:SF13 FERMITIN 2-RELATED FERMITIN 2-RELATED protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-substrate junction#GO:0030055 DROME|FlyBase=FBgn0032946|UniProtKB=M9PDX8 M9PDX8 nrv3 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;import across plasma membrane#GO:0098739;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;potassium ion homeostasis#GO:0055075;localization#GO:0051179 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0035647|UniProtKB=Q9VRR0 Q9VRR0 Dmel\CG10486 PTHR24064:SF316 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0033438|UniProtKB=Q8MPP3 Q8MPP3 Mmp2 PTHR10201:SF291 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE 1, ISOFORM C-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0030005|UniProtKB=Q0IGR3 Q0IGR3 spdt PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0035692|UniProtKB=Q9VRV7 Q9VRV7 Sf3b6 PTHR48526:SF2 SPLICING FACTOR 3B SUBUNIT 6 SPLICING FACTOR 3B SUBUNIT 6 DROME|FlyBase=FBgn0004511|UniProtKB=Q9VYU7 Q9VYU7 dy PTHR46560:SF1 CYPHER, ISOFORM B DUSKY cell morphogenesis#GO:0000902;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 DROME|FlyBase=FBgn0033629|UniProtKB=A1Z8K7 A1Z8K7 Tsp47F PTHR19282:SF273 TETRASPANIN TETRASPANIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035741|UniProtKB=Q9VS19 Q9VS19 BBS1 PTHR20870:SF0 BARDET-BIEDL SYNDROME 1 PROTEIN BBSOME COMPLEX MEMBER BBS1 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;cellular component organization#GO:0016043;cilium assembly#GO:0060271 intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;BBSome#GO:0034464;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0037849|UniProtKB=Q9VGV1 Q9VGV1 Dmel\CG4596 PTHR31777:SF0 TRANSMEMBRANE PROTEIN 169 TRANSMEMBRANE PROTEIN 169 DROME|FlyBase=FBgn0035951|UniProtKB=Q95R98 Q95R98 Dmel\CG5068 PTHR14189:SF0 PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED PROTEIN PHOSPHATASE METHYLESTERASE 1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033713|UniProtKB=Q0E9B5 Q0E9B5 Dmc1 PTHR21575:SF12 PROTEIN HID1 PROTEIN HID1 developmental process#GO:0032502;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;anatomical structure maturation#GO:0071695;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;developmental maturation#GO:0021700 Golgi stack#GO:0005795;cytosol#GO:0005829;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0030925|UniProtKB=A8JUP7 A8JUP7 Hayan PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0035325|UniProtKB=Q8SXL5 Q8SXL5 Dmel\CG13806 PTHR23301:SF115 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0086680|UniProtKB=P16241 P16241 vvl PTHR11636:SF140 POU DOMAIN POU DOMAIN PROTEIN 2, ISOFORM B-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0040309|UniProtKB=Q9V3P0 Q9V3P0 Prx2 PTHR10681:SF163 THIOREDOXIN PEROXIDASE PEROXIREDOXIN 2-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular process#GO:0009987;response to stress#GO:0006950;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;peroxidase#PC00180 DROME|FlyBase=FBgn0015756|UniProtKB=P50882 P50882 RpL9 PTHR11655:SF16 60S/50S RIBOSOMAL PROTEIN L6/L9 LARGE RIBOSOMAL SUBUNIT PROTEIN UL6 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 DROME|FlyBase=FBgn0265272|UniProtKB=Q29QL9 Q29QL9 anon-SAGE:Wang-129 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 DROME|FlyBase=FBgn0027532|UniProtKB=Q9XZ11 Q9XZ11 Dmel\CG7139 PTHR46535:SF1 NEDD4-BINDING PROTEIN 2 NEDD4-BINDING PROTEIN 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 DROME|FlyBase=FBgn0288875|UniProtKB=Q9VAQ0 Q9VAQ0 Cul5 PTHR11932:SF76 CULLIN CULLIN-5 structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056 Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0025776|UniProtKB=Q7KUL4 Q7KUL4 ind PTHR24339:SF28 HOMEOBOX PROTEIN EMX-RELATED E5-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;head development#GO:0060322;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0000395|UniProtKB=Q9W2H2 Q9W2H2 cv-2 PTHR46698:SF10 CROSSVEINLESS 2 CROSSVEINLESS 2 binding#GO:0005488;protein binding#GO:0005515;cytokine binding#GO:0019955 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of BMP signaling pathway#GO:0030510;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of BMP signaling pathway#GO:0030513;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037646|UniProtKB=Q9VHJ5 Q9VHJ5 CAHbeta PTHR11002:SF76 CARBONIC ANHYDRASE CARBONIC ANHYDRASE lyase#PC00144;dehydratase#PC00091 DROME|FlyBase=FBgn0037995|UniProtKB=Q8T3U8 Q8T3U8 Adk1 PTHR45769:SF3 ADENOSINE KINASE ADENOSINE KINASE nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031356|UniProtKB=Q9VQ34 Q9VQ34 Dmel\CG17660 PTHR21229:SF86 LUNG SEVEN TRANSMEMBRANE RECEPTOR GH17801P endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0262656|UniProtKB=Q9W4S7 Q9W4S7 Myc PTHR45851:SF3 MYC PROTO-ONCOGENE MYC PROTO-ONCOGENE PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 p53 pathway feedback loops 2#P04398>Myc#P04649;Oxidative stress response#P00046>Myc#P01124;PDGF signaling pathway#P00047>c-Myc#P01172;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 DROME|FlyBase=FBgn0051098|UniProtKB=Q9VBT1 Q9VBT1 Dmel\CG31098 PTHR11012:SF19 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0037722|UniProtKB=Q9VHA4 Q9VHA4 Dmel\CG8319 PTHR24390:SF278 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 772 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0039637|UniProtKB=Q9VAP3 Q9VAP3 Ctl2 PTHR12385:SF14 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0027343|UniProtKB=O77438 O77438 fz3 PTHR11309:SF142 FRIZZLED FRIZZLED-3 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 DROME|FlyBase=FBgn0032467|UniProtKB=Q9VK44 Q9VK44 Ube4B PTHR13931:SF2 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 B acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0038722|UniProtKB=Q9VDV3 Q9VDV3 Nup58 PTHR13437:SF2 NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1 NUCLEOPORIN P58_P45 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nuclear transport#GO:0051169;intracellular transport#GO:0046907;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transporter#PC00227 DROME|FlyBase=FBgn0039349|UniProtKB=Q9VBP6 Q9VBP6 Ssadh PTHR43353:SF14 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824 DROME|FlyBase=FBgn0044419|UniProtKB=Q8IQ56 Q8IQ56 Pmi PTHR15099:SF2 PROTEIN PM1 TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840 mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0013279|UniProtKB=Q9BIR7 Q9BIR7 Hsp70Bc PTHR19375:SF518 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN AA-RELATED hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 DROME|FlyBase=FBgn0005654|UniProtKB=Q7K2L1 Q7K2L1 Orc3 PTHR12748:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nuclear pre-replicative complex#GO:0005656;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nuclear origin of replication recognition complex#GO:0005664;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;DNA replication preinitiation complex#GO:0031261;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;pre-replicative complex#GO:0036387;intracellular organelle#GO:0043229 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0000229|UniProtKB=P92208 P92208 bsk PTHR24055:SF598 MITOGEN-ACTIVATED PROTEIN KINASE STRESS-ACTIVATED PROTEIN KINASE JNK catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Apoptosis signaling pathway#P00006>JNK#P00274;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Oxidative stress response#P00046>JNK1/2#P01129;Toll receptor signaling pathway#P00054>JNK#P01375;Parkinson disease#P00049>SAPK#P01219;Angiogenesis#P00005>JNK1#P00221;Ras Pathway#P04393>JNK#P04572;TGF-beta signaling pathway#P00052>JNK#P01284;FGF signaling pathway#P00021>JNK1-3#P00628;Integrin signalling pathway#P00034>Jnk#P00951;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545 DROME|FlyBase=FBgn0035750|UniProtKB=Q9VS31 Q9VS31 Dmel\CG14826 PTHR21398:SF11 AGAP007094-PA HDC15381-RELATED DROME|FlyBase=FBgn0037655|UniProtKB=Q95RX5 Q95RX5 Kcmf1 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038806|UniProtKB=Q9VDL1 Q9VDL1 CG5412 PTHR48070:SF6 ESTERASE OVCA2 ESTERASE OVCA2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 esterase#PC00097;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0030680|UniProtKB=Q9VXQ6 Q9VXQ6 Dmel\CG8944 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0003326|UniProtKB=P21520 P21520 sca PTHR19143:SF444 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-3 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0036449|UniProtKB=E1JI03 E1JI03 bmm PTHR12406:SF41 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED TRIACYLGLYCEROL LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;triacylglycerol lipase activity#GO:0004806;hydrolase activity#GO:0016787 acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;neutral lipid catabolic process#GO:0046461;chemical homeostasis#GO:0048878;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid catabolic process#GO:0016042;cellular process#GO:0009987;triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503;homeostatic process#GO:0042592;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811 phospholipase#PC00186 DROME|FlyBase=FBgn0004430|UniProtKB=P37160 P37160 LysS PTHR11407:SF63 LYSOZYME C LYSOZYME hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;lysozyme activity#GO:0003796;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycosidase#PC00110 DROME|FlyBase=FBgn0038691|UniProtKB=Q9VDY7 Q9VDY7 Dmel\CG5250 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;inorganic ion homeostasis#GO:0098771;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0000715|UniProtKB=P10552 P10552 FMRFa PTHR20986:SF22 FMRFAMIDE-RELATED PEPTIDES FMRFAMIDE-RELATED PEPTIDES DROME|FlyBase=FBgn0030354|UniProtKB=Q9VYS3 Q9VYS3 Upf1 PTHR10887:SF364 DNA2/NAM7 HELICASE FAMILY REGULATOR OF NONSENSE TRANSCRIPTS 1 RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 DROME|FlyBase=FBgn0001225|UniProtKB=P02517 P02517 Hsp26 PTHR45640:SF40 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN 22-RELATED metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;protein folding#GO:0006457 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0038487|UniProtKB=Q8IH13 Q8IH13 TwdlW PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0000326|UniProtKB=Q9W2F4 Q9W2F4 clt PTHR11559:SF430 CARBOXYLESTERASE CARBOXYLESTERASE esterase#PC00097 DROME|FlyBase=FBgn0052056|UniProtKB=Q9VT88 Q9VT88 scramb1 PTHR23248:SF9 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 lipid localization#GO:0010876;localization#GO:0051179;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0005626|UniProtKB=P18459 P18459 ple PTHR11473:SF15 AROMATIC AMINO ACID HYDROXYLASE TYROSINE 3-MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 cell communication#GO:0007154;multicellular organismal reproductive process#GO:0048609;trans-synaptic signaling#GO:0099537;cognition#GO:0050890;nervous system process#GO:0050877;anterograde trans-synaptic signaling#GO:0098916;reproductive process#GO:0022414;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;system process#GO:0003008;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;synaptic transmission, dopaminergic#GO:0001963;cellular process#GO:0009987 axon#GO:0030424;perikaryon#GO:0043204;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;cell body#GO:0044297;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Dopamine receptor mediated signaling pathway#P05912>TH#P05970;Adrenaline and noradrenaline biosynthesis#P00001>TH#P00062 DROME|FlyBase=FBgn0041588|UniProtKB=Q9NG60 Q9NG60 eIF2D PTHR12217:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 2D EUKARYOTIC TRANSLATION INITIATION FACTOR 2D translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;cytoplasmic translational initiation#GO:0002183;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 DROME|FlyBase=FBgn0037276|UniProtKB=Q9VN57 Q9VN57 Ccdc39 PTHR18962:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;pattern specification process#GO:0007389;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;localization#GO:0051179;determination of left/right symmetry#GO:0007368;cell motility#GO:0048870;microtubule-based movement#GO:0007018;transport#GO:0006810;developmental process#GO:0032502;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;establishment of localization#GO:0051234;plasma membrane bounded cell projection organization#GO:0120036;regionalization#GO:0003002;multicellular organismal process#GO:0032501;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based transport#GO:0099111;inner dynein arm assembly#GO:0036159;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;left/right pattern formation#GO:0060972;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;determination of bilateral symmetry#GO:0009855;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0051950|UniProtKB=Q8IPZ7 Q8IPZ7 Sbat PTHR10701:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT RNA splicing factor#PC00148 DROME|FlyBase=FBgn0262952|UniProtKB=P18931 P18931 mt:ND4 PTHR43507:SF20 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;NADH dehydrogenase activity#GO:0003954 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;aerobic respiration#GO:0009060;monoatomic ion transport#GO:0006811;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;energy derivation by oxidation of organic compounds#GO:0015980;establishment of localization#GO:0051234;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810;metabolic process#GO:0008152 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176 DROME|FlyBase=FBgn0004404|UniProtKB=C0HKA1 C0HKA1 RpS14b PTHR11759:SF1 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;translation#GO:0006412 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0267002|UniProtKB=A1ZAJ2 A1ZAJ2 unc-104 PTHR24115:SF1030 KINESIN-RELATED KINESIN-LIKE PROTEIN UNC-104 plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;retrograde axonal transport#GO:0008090;axonal transport#GO:0098930;organelle localization#GO:0051640;cytosolic transport#GO:0016482;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088 microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037906|UniProtKB=Q8INK6 Q8INK6 PGRP-LB PTHR11022:SF77 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LB hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;peptidoglycan muralytic activity#GO:0061783;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824 defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;response to external stimulus#GO:0009605;defense response#GO:0006952;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0054026|UniProtKB=Q2PE22 Q2PE22 Dmel\CG34026 PTHR37685:SF1 GEO11136P1-RELATED GEO11136P1-RELATED DROME|FlyBase=FBgn0039137|UniProtKB=Q9VCE9 Q9VCE9 Epp PTHR16469:SF27 UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BB-RELATED DROME|FlyBase=FBgn0036716|UniProtKB=Q9VVG1 Q9VVG1 Dmel\CG13728 PTHR15708:SF4 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED FI21477P1-RELATED protein binding#GO:0005515;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0030418|UniProtKB=Q9VYJ6 Q9VYJ6 Dmel\CG4004 PTHR21505:SF8 MADF DOMAIN-CONTAINING PROTEIN-RELATED DPT-YFP REPRESSOR BY OVEREXPRESSION, ISOFORM D-RELATED DROME|FlyBase=FBgn0011260|UniProtKB=Q24323 Q24323 Sema2a PTHR11036:SF90 SEMAPHORIN SEMAPHORIN-2A signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon development#GO:0061564;axon guidance#GO:0007411;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 DROME|FlyBase=FBgn0031523|UniProtKB=Q9VQP2 Q9VQP2 Dmel\CG15408 PTHR48021:SF33 FAMILY NOT NAMED AT22075P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0035145|UniProtKB=Q9W0P8 Q9W0P8 MED14 PTHR12809:SF2 MEDIATOR COMPLEX SUBUNIT MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0033730|UniProtKB=A1Z8Z3 A1Z8Z3 Cpr49Ag PTHR10380:SF215 CUTICLE PROTEIN CUTICULAR PROTEIN 49AG extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0041775|UniProtKB=M9PF20 M9PF20 tral PTHR13586:SF0 SCD6 PROTEIN-RELATED TRAILER HITCH, ISOFORM H RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;P-body assembly#GO:0033962;cellular process#GO:0009987;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0025454|UniProtKB=Q9V674 Q9V674 Cyp6g1 PTHR24292:SF45 CYTOCHROME P450 CYTOCHROME P450 6G1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0031546|UniProtKB=R9PY49 R9PY49 Dmel\CG8851 PTHR23162:SF10 OUTER DENSE FIBER OF SPERM TAILS 2 FI13205P regulation of cell projection assembly#GO:0060491;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0025620|UniProtKB=O77436 O77436 EG:34F3.5 PTHR11012:SF56 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0261649|UniProtKB=Q86B91 Q86B91 tinc PTHR21579:SF20 PROTEIN TINCAR PROTEIN TINCAR DROME|FlyBase=FBgn0041706|UniProtKB=Q9W1A7 Q9W1A7 BEST:GH04269 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220 DROME|FlyBase=FBgn0001077|UniProtKB=P02835 P02835 ftz PTHR45659:SF24 HOMEOBOX PROTEIN HOX HOMEOTIC PROTEIN ANTENNAPEDIA-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032633|UniProtKB=Q960C5 Q960C5 Lrch PTHR45752:SF206 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0004687|UniProtKB=P54357 P54357 Mlc-c PTHR23048:SF0 MYOSIN LIGHT CHAIN 1, 3 FI08416P-RELATED intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0051104|UniProtKB=Q9VBT4 Q9VBT4 CG13657 PTHR11012:SF12 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0085354|UniProtKB=Q9VXC1 Q9VXC1 Dmel\CG34325 PTHR24205:SF16 FOUR AND A HALF LIM DOMAINS PROTEIN GH01042P-RELATED transcription cofactor#PC00217 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 DROME|FlyBase=FBgn0034825|UniProtKB=Q9W1U3 Q9W1U3 Gpdh2 PTHR11728:SF8 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0034398|UniProtKB=Q4QQB9 Q4QQB9 dmCG15098 PTHR36694:SF14 PASIFLORA 1, ISOFORM A-RELATED LP21121P DROME|FlyBase=FBgn0032296|UniProtKB=Q9VKQ6 Q9VKQ6 CG6729 PTHR13091:SF0 AMPLIFIED IN BREAST CANCER 2-RELATED NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8 nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 DROME|FlyBase=FBgn0011584|UniProtKB=Q9VL49 Q9VL49 Trp1 PTHR12443:SF9 TRANSLOCATION PROTEIN SEC62 TRANSLOCATION PROTEIN SEC62 transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization within membrane#GO:0051668;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030961|UniProtKB=Q9VWP9 Q9VWP9 Dmel\CG7058 PTHR24413:SF229 SPECKLE-TYPE POZ PROTEIN GH01369P ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0001319|UniProtKB=P56721 P56721 kn PTHR10747:SF38 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COLLIER DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;P53-like transcription factor#PC00253 DROME|FlyBase=FBgn0034456|UniProtKB=A1ZBM7 A1ZBM7 Ir56b PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0038549|UniProtKB=Q8SX40 Q8SX40 Nnk PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0034172|UniProtKB=A1ZAM0 A1ZAM0 Dmel\CG6665 PTHR21425:SF3 NICE-3 LIPID TRANSPORT AUXILIARY PROTEIN 1 DROME|FlyBase=FBgn0259101|UniProtKB=Q9VZ32 Q9VZ32 CG1961 PTHR11575:SF32 5'-NUCLEOTIDASE-RELATED APYRASE catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 purine-containing compound catabolic process#GO:0072523;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 DROME|FlyBase=FBgn0086704|UniProtKB=Q9VA06 Q9VA06 stops PTHR20966:SF2 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238 DROME|FlyBase=FBgn0000826|UniProtKB=O46308 O46308 png PTHR44305:SF2 SI:DKEY-192D15.2-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0039367|UniProtKB=Q9VBM7 Q9VBM7 Dmel\CG17197 PTHR22883:SF511 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein targeting to membrane#GO:0006612;developmental process#GO:0032502;developmental maturation#GO:0021700;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein targeting#GO:0006605;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034437|UniProtKB=A1ZBK1 A1ZBK1 Dmel\CG10051 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0069938|UniProtKB=Q5LJU1 Q5LJU1 Cnep1r1 PTHR20996:SF1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 intracellular anatomical structure#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;membrane protein complex#GO:0098796 phosphatase modulator#PC00184 DROME|FlyBase=FBgn0031069|UniProtKB=Q9VWC8 Q9VWC8 Abcd3 PTHR11384:SF62 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 3 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monocarboxylic acid transmembrane transporter activity#GO:0008028;nucleotide binding#GO:0000166;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265 organelle organization#GO:0006996;cellular process#GO:0009987;lipid catabolic process#GO:0016042;establishment of localization in cell#GO:0051649;metabolic process#GO:0008152;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;fatty acid oxidation#GO:0019395;cellular component organization or biogenesis#GO:0071840;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;peroxisome organization#GO:0007031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;fatty acid catabolic process#GO:0009062;macromolecule localization#GO:0033036;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;lipid transport#GO:0006869;fatty acid metabolic process#GO:0006631;intracellular transport#GO:0046907;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;transport#GO:0006810;establishment of localization#GO:0051234;lipid modification#GO:0030258;primary metabolic process#GO:0044238;catabolic process#GO:0009056;carboxylic acid transmembrane transport#GO:1905039;lipid oxidation#GO:0034440;fatty acid transport#GO:0015908;localization#GO:0051179;peroxisomal transport#GO:0043574;monocarboxylic acid transport#GO:0015718 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0261592|UniProtKB=P29327 P29327 RpS6 PTHR11502:SF6 40S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN ES6 ribosomal protein#PC00202 DROME|FlyBase=FBgn0031774|UniProtKB=Q9VMI0 Q9VMI0 Dmel\CG9147 PTHR33558:SF1 GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0003464|UniProtKB=P27398 P27398 sol PTHR10183:SF382 CALPAIN CALPAIN-15 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0025578|UniProtKB=P82384 P82384 Lcp9 PTHR10380:SF228 CUTICLE PROTEIN CUTICULAR PROTEIN 11A-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0031086|UniProtKB=Q9W5X5 Q9W5X5 fd19B PTHR11829:SF402 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD3-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0016919|UniProtKB=Q7KRS6 Q7KRS6 nompB PTHR44117:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG NO MECHANORECEPTOR POTENTIAL B, ISOFORM D binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;ciliary base#GO:0097546;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064 DROME|FlyBase=FBgn0032261|UniProtKB=Q9VKU3 Q9VKU3 FBgn 32261 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR LARGE RIBOSOMAL SUBUNIT PROTEIN ML62 catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;translation factor activity#GO:0180051;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 translation release factor#PC00225 DROME|FlyBase=FBgn0032681|UniProtKB=E1JHK9 E1JHK9 Dmel\CG10283 PTHR22115:SF4 C3ORF6 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0026593|UniProtKB=D5SHT6 D5SHT6 CG5707-RA PTHR43329:SF4 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 DROME|FlyBase=FBgn0261561|UniProtKB=A0A0B4KGL2 A0A0B4KGL2 CG31554 PTHR13555:SF25 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1A C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0037506|UniProtKB=Q9VIB2 Q9VIB2 Mics1 PTHR23291:SF112 BAX INHIBITOR-RELATED GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;metal ion transport#GO:0030001;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;organelle organization#GO:0006996;mitochondrial calcium ion transmembrane transport#GO:0006851;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;inner mitochondrial membrane organization#GO:0007007;mitochondrion organization#GO:0007005;monoatomic cation transmembrane transport#GO:0098655;membrane organization#GO:0061024;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;calcium ion transport#GO:0006816 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0260750|UniProtKB=Q9VL10 Q9VL10 Mulk PTHR12358:SF116 SPHINGOSINE KINASE ACYLGLYCEROL KINASE, MITOCHONDRIAL phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingoid biosynthetic process#GO:0046520;primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0038248|UniProtKB=Q9VFH6 Q9VFH6 CG7886 PTHR24110:SF3 CENTROSOMAL PROTEIN OF 78 KDA CENTROSOMAL PROTEIN OF 78 KDA cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0033121|UniProtKB=Q9V979 Q9V979 Cyp6u1 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0028533|UniProtKB=Q9V3P4 Q9V3P4 anon-WO0140519.73 PTHR20993:SF0 GH07914P GH07914P DROME|FlyBase=FBgn0265523|UniProtKB=M9PGZ8 M9PGZ8 Smr PTHR13992:SF39 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR SMRTER, ISOFORM G regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0260229|UniProtKB=P0C919 P0C919 Mocs2A PTHR33359:SF1 MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT metabolic process#GO:0008152;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;macromolecule metabolic process#GO:0043170;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;biosynthetic process#GO:0009058 cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0035435|UniProtKB=A0A2U8U156 A0A2U8U156 PIG-C PTHR12982:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS C PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0031494|UniProtKB=Q9VQK8 Q9VQK8 Dmel\CG17219 PTHR14614:SF177 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0025382|UniProtKB=O76901 O76901 Rab27 PTHR47977:SF123 RAS-RELATED PROTEIN RAB EG:80H7.4 PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787 regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;positive regulation of secretion#GO:0051047;export from cell#GO:0140352;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulation of transport#GO:0051049;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532 apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;apical part of cell#GO:0045177 small GTPase#PC00208 DROME|FlyBase=FBgn0004556|UniProtKB=P26802 P26802 Dbp73D PTHR24031:SF68 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX51 RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0032518|UniProtKB=Q9VJY6 Q9VJY6 RpL24 PTHR10792:SF1 60S RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN EL24 binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625 ribosomal protein#PC00202 DROME|FlyBase=FBgn0039809|UniProtKB=Q9VA28 Q9VA28 Dmel\CG15547 PTHR46161:SF1 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE 5 nucleotide kinase#PC00172;kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 DROME|FlyBase=FBgn0052857|UniProtKB=Q8SY96 Q8SY96 CG33502 PTHR11178:SF1 IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0259678|UniProtKB=A1Z7Y7 A1Z7Y7 sqa PTHR24347:SF393 SERINE/THREONINE-PROTEIN KINASE SPAGHETTI-SQUASH ACTIVATOR, ISOFORM C protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877 DROME|FlyBase=FBgn0029969|UniProtKB=Q9W3N9 Q9W3N9 Acat1 PTHR18919:SF156 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid metabolic process#GO:0008202 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 acyltransferase#PC00042;transferase#PC00220 CCKR signaling map#P06959>ACAT1#G06992;CCKR signaling map#P06959>ACAT1#G07285 DROME|FlyBase=FBgn0041622|UniProtKB=P82985 P82985 Or69a PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031725|UniProtKB=Q9VMN9 Q9VMN9 DIP-eta PTHR12231:SF282 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN ETA, ISOFORM B-RELATED protein binding#GO:0005515;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;synapse organization#GO:0050808;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell junction#GO:0030054;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0042186|UniProtKB=Q9VQ98 Q9VQ98 Dmel\CG17239 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0026760|UniProtKB=Q9VJX9 Q9VJX9 Tehao PTHR24365:SF556 TOLL-LIKE RECEPTOR PROTEIN TOLL-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;immune system process#GO:0002376;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Toll pathway-drosophila#P06217>TL#P06337;Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0033178|UniProtKB=Q7JRM5 Q7JRM5 Dmel\CG11127 PTHR21461:SF100 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GH12965P glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033086|UniProtKB=Q8MLL3 Q8MLL3 Coq10 PTHR12901:SF10 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL DROME|FlyBase=FBgn0025839|UniProtKB=O97418 O97418 ND-B14.5A PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037501|UniProtKB=Q9VIA5 Q9VIA5 Ir84a PTHR42643:SF36 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 84A transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0025634|UniProtKB=Q9W5E2 Q9W5E2 Dmel\CG13367 PTHR13340:SF2 GATA ZINC FINGER DOMAIN-CONTAINING GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0032439|UniProtKB=Q9VK76 Q9VK76 Ref2 PTHR19965:SF35 RNA AND EXPORT FACTOR BINDING PROTEIN THO COMPLEX SUBUNIT 4 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0025115|UniProtKB=P56544 P56544 Acyp PTHR10029:SF3 ACYLPHOSPHATASE ACYLPHOSPHATASE-1 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 DROME|FlyBase=FBgn0026777|UniProtKB=Q9V3W9 Q9V3W9 Rad23 PTHR10621:SF0 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;ubiquitin binding#GO:0043130 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0002707|UniProtKB=Q24087 Q24087 mei-9 PTHR10150:SF0 DNA REPAIR ENDONUCLEASE XPF DNA REPAIR ENDONUCLEASE XPF single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA binding#GO:0003677;damaged DNA binding#GO:0003684;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 organelle fission#GO:0048285;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;homologous recombination#GO:0035825;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 DROME|FlyBase=FBgn0020388|UniProtKB=Q9VTZ1 Q9VTZ1 Gcn5 PTHR45750:SF5 GH11602P HISTONE ACETYLTRANSFERASE protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;chromatin organization#GO:0006325;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 Notch signaling pathway#P00045>CoA#P01100 DROME|FlyBase=FBgn0050464|UniProtKB=A1ZA17 A1ZA17 Ir52d PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0015577|UniProtKB=Q9VIB1 Q9VIB1 alpha-Est9 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0040273|UniProtKB=Q9V460 Q9V460 Spt5 PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0038349|UniProtKB=Q9VF51 Q9VF51 AOX3 PTHR11908:SF132 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE 1-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0030221|UniProtKB=Q9W2S9 Q9W2S9 Rab9Db PTHR47980:SF101 LD44762P IP08727P-RELATED endocytic recycling#GO:0032456;export from cell#GO:0140352;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;endosomal transport#GO:0016197;exocytosis#GO:0006887;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810 Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0029003|UniProtKB=Q9U3W6 Q9U3W6 mab-21 PTHR10656:SF80 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21 nucleotidyltransferase#PC00174;transferase#PC00220 DROME|FlyBase=FBgn0039102|UniProtKB=Q9VCJ8 Q9VCJ8 SPE PTHR24260:SF144 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED Toll pathway-drosophila#P06217>SPE#P06340 DROME|FlyBase=FBgn0028956|UniProtKB=Q9V818 Q9V818 mthl3 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0261274|UniProtKB=Q9V3A6 Q9V3A6 Ero1L PTHR12613:SF0 ERO1-RELATED ERO1-LIKE PROTEIN protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;signal transduction#GO:0007165;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0033815|UniProtKB=Q0IGS7 Q0IGS7 Dmel\CG4676 PTHR22883:SF414 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC24-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0000079|UniProtKB=P08144 P08144 Amy-p PTHR43447:SF61 ALPHA-AMYLASE ALPHA-AMYLASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 amylase#PC00048 DROME|FlyBase=FBgn0030748|UniProtKB=Q8IR14 Q8IR14 Traf-like PTHR10131:SF167 TNF RECEPTOR ASSOCIATED FACTOR RE66324P tumor necrosis factor receptor superfamily binding#GO:0032813;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488 cytokine-mediated signaling pathway#GO:0019221;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035693|UniProtKB=Q9VRV9 Q9VRV9 148274_at PTHR10527:SF3 IMPORTIN BETA TRANSPORTIN-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 DROME|FlyBase=FBgn0036811|UniProtKB=Q9VVS4 Q9VVS4 MED11 PTHR22890:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592 DROME|FlyBase=FBgn0038903|UniProtKB=Q9VD81 Q9VD81 Polr1H PTHR11239:SF14 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on RNA#GO:0140098 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0037235|UniProtKB=Q960K3 Q960K3 Dmel\CG1103 PTHR31548:SF1 CLARIN LD47387P DROME|FlyBase=FBgn0038344|UniProtKB=Q9VF56 Q9VF56 obe PTHR24075:SF6 SEC63 DOMAIN-CONTAINING ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;RNA binding#GO:0003723;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037802|UniProtKB=Q9VH08 Q9VH08 Sirt6 PTHR11085:SF19 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;transcription corepressor activity#GO:0003714;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;deacylase activity#GO:0160215;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;transcription regulator activity#GO:0140110;acyltransferase activity#GO:0016746 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0032287|UniProtKB=Q9VKR4 Q9VKR4 Gcst PTHR43757:SF2 AMINOMETHYLTRANSFERASE AMINOMETHYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220;methyltransferase#PC00155 DROME|FlyBase=FBgn0051151|UniProtKB=Q3LHL9 Q3LHL9 wge PTHR12505:SF24 PHD FINGER TRANSCRIPTION FACTOR PROTEIN WINGED EYE gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0051368|UniProtKB=Q7KSN8 Q7KSN8 salsa PTHR10887:SF5 DNA2/NAM7 HELICASE FAMILY RNA HELICASE AQUARIUS RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA helicase#PC00032 DROME|FlyBase=FBgn0034435|UniProtKB=A1ZBJ8 A1ZBJ8 fest PTHR39075:SF1 FI19908P1 FI19908P1 DROME|FlyBase=FBgn0039505|UniProtKB=Q9VB51 Q9VB51 Dmel\CG5934 PTHR21614:SF0 SHORT COILED COIL PROTEIN SHORT COILED-COIL PROTEIN organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi apparatus subcompartment#GO:0098791 DROME|FlyBase=FBgn0025455|UniProtKB=O96433 O96433 CycT PTHR10026:SF51 CYCLIN CYCLIN-T molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription elongation#GO:0032784;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 kinase activator#PC00138;kinase modulator#PC00140 DROME|FlyBase=FBgn0035539|UniProtKB=Q95RQ1 Q95RQ1 slow PTHR14949:SF61 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 LD16414P binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0267106|UniProtKB=A0A0B4LHW5 A0A0B4LHW5 Dmel\CG45546 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0031522|UniProtKB=Q9VQP1 Q9VQP1 Dmel\CG3285 PTHR48021:SF33 FAMILY NOT NAMED AT22075P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0023477|UniProtKB=Q9W1G0 Q9W1G0 Taldo PTHR10683:SF44 TRANSALDOLASE TRANSALDOLASE transaldolase activity#GO:0004801;transketolase or transaldolase activity#GO:0016744;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 lyase#PC00144;aldolase#PC00044;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Transaldolase#P03081 DROME|FlyBase=FBgn0038922|UniProtKB=Q9VD58 Q9VD58 Idh3b PTHR11835:SF84 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 carboxylic acid metabolic process#GO:0019752;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;alcohol metabolic process#GO:0006066;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0264848|UniProtKB=Q9VTY6 Q9VTY6 vih PTHR24068:SF144 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 C-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of chromosome segregation#GO:0051983;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 DROME|FlyBase=FBgn0250862|UniProtKB=Q9VYG9 Q9VYG9 CG4346 PTHR12253:SF34 RH14732P PHOSPHOLIPASE A2 DROME|FlyBase=FBgn0034684|UniProtKB=Q9W2A3 Q9W2A3 Dmel\CG13501 PTHR15599:SF1 RTDR1 RADIAL SPOKE HEAD 14 HOMOLOG DROME|FlyBase=FBgn0037430|UniProtKB=Q9VI07 Q9VI07 Osi20 PTHR21879:SF2 FI03362P-RELATED-RELATED OSIRIS 20 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039214|UniProtKB=Q9VC56 Q9VC56 puf PTHR24006:SF943 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE PUF deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0036806|UniProtKB=Q9VVR9 Q9VVR9 Cyp12c1 PTHR24305:SF238 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0062413|UniProtKB=M9NE97 M9NE97 Ctr1A PTHR12483:SF115 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS COPPER TRANSPORT PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;transition metal ion transport#GO:0000041;copper ion transmembrane transport#GO:0035434;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0037544|UniProtKB=Q9VHW5 Q9VHW5 anon-WO0118547.426 PTHR44873:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL chaperone#PC00072 DROME|FlyBase=FBgn0036031|UniProtKB=Q9VT34 Q9VT34 Dmel\CG6761 PTHR20946:SF1 SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION SANT AND BTB DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0042182|UniProtKB=Q8MSK0 Q8MSK0 CG31188 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038720|UniProtKB=Q9VDV5 Q9VDV5 Dmel\CG6231 PTHR24064:SF467 SOLUTE CARRIER FAMILY 22 MEMBER FI01439P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0000083|UniProtKB=P22464 P22464 AnxB9 PTHR10502:SF233 ANNEXIN ANNEXIN B9 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886 calcium-binding protein#PC00060 DROME|FlyBase=FBgn0024804|UniProtKB=O61305 O61305 Dbp80 PTHR47958:SF31 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 DROME|FlyBase=FBgn0035458|UniProtKB=Q9VZN1 Q9VZN1 ppk27 PTHR11690:SF237 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 27-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0003744|UniProtKB=Q9NBK5 Q9NBK5 trc PTHR24356:SF450 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TRICORNERED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;establishment or maintenance of cell polarity#GO:0007163;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0028476|UniProtKB=Q8I077 Q8I077 Usp1 PTHR24006:SF905 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 1 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0051105|UniProtKB=Q8IMV2 Q8IMV2 ppk22 PTHR11690:SF253 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 18-RELATED monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0015520|UniProtKB=Q24113 Q24113 nonA-l PTHR23189:SF102 RNA RECOGNITION MOTIF-CONTAINING PROTEIN NO-ON-TRANSIENT A nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037537|UniProtKB=Q9VHX4 Q9VHX4 Ar5 PTHR11732:SF482 ALDO/KETO REDUCTASE LD24679P oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0039152|UniProtKB=Q9VCD1 Q9VCD1 Root PTHR23159:SF65 CENTROSOMAL PROTEIN 2 ROOTLETIN, ISOFORM D chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0039002|UniProtKB=Q9VCW5 Q9VCW5 Dmel\CG17625 PTHR12301:SF8 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 DROME|FlyBase=FBgn0287234|UniProtKB=Q8SZK9 Q8SZK9 slf PTHR21407:SF5 RE43931P-RELATED HL04814P DROME|FlyBase=FBgn0037341|UniProtKB=Q8IGV3 Q8IGV3 Dmel\CG12746 PTHR10165:SF35 LIPID PHOSPHATE PHOSPHATASE RE23632P phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;dephosphorylation#GO:0016311;lipid modification#GO:0030258 membrane#GO:0016020;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0023519|UniProtKB=Q9W547 Q9W547 mRpL16 PTHR12220:SF13 50S/60S RIBOSOMAL PROTEIN L16 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 ribosomal protein#PC00202 Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005 DROME|FlyBase=FBgn0031737|UniProtKB=Q9VMM6 Q9VMM6 obst-E PTHR23301:SF98 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;carbohydrate derivative binding#GO:0097367;structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0032701|UniProtKB=Q9VJ62 Q9VJ62 CG10341 PTHR31633:SF1 H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;ribosome biogenesis#GO:0042254 protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904 DROME|FlyBase=FBgn0016061|UniProtKB=A0A0B4K7N1 A0A0B4K7N1 side PTHR23278:SF4 SIDESTEP PROTEIN SIDESTEP, ISOFORM C immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0040069|UniProtKB=Q9NFP1 Q9NFP1 vanin-like PTHR10609:SF28 BIOTINIDASE-RELATED CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752 hydrolase#PC00121 DROME|FlyBase=FBgn0037782|UniProtKB=Q9VH32 Q9VH32 Npc2d PTHR11306:SF36 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NIEMANN-PICK TYPE C-2C-RELATED binding#GO:0005488;sterol binding#GO:0032934;lipid binding#GO:0008289;steroid binding#GO:0005496 macromolecule localization#GO:0033036;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;establishment of localization#GO:0051234;sterol transport#GO:0015918 DROME|FlyBase=FBgn0039205|UniProtKB=Q9VC65 Q9VC65 Dmel\CG13623 PTHR43011:SF1 IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;iron ion binding#GO:0005506 protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0031495|UniProtKB=Q9VQK9 Q9VQK9 GABPI PTHR22883:SF475 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC23 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 protein targeting#GO:0006605;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;protein localization to plasma membrane#GO:0072659;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein targeting to membrane#GO:0006612;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0290398|UniProtKB=Q9VBH3 Q9VBH3 dysf PTHR23043:SF39 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA DYSFUSION, ISOFORM D DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0000346|UniProtKB=P46461 P46461 comt PTHR23078:SF3 VESICULAR-FUSION PROTEIN NSF VESICLE-FUSING ATPASE hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;intra-Golgi vesicle-mediated transport#GO:0006891;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>NSF#P05774;Ionotropic glutamate receptor pathway#P00037>NSF#P01020 DROME|FlyBase=FBgn0013973|UniProtKB=Q9VA09 Q9VA09 Gycbeta100B PTHR45655:SF2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;response to abiotic stimulus#GO:0009628;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleoside phosphate metabolic process#GO:0006753;response to oxygen levels#GO:0070482;primary metabolic process#GO:0044238;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cytosol#GO:0005829 cyclase#PC00079;guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581;Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726 DROME|FlyBase=FBgn0260857|UniProtKB=Q9VVX6 Q9VVX6 Bet1 PTHR12791:SF64 GOLGI SNARE BET1-RELATED BET1 HOMOLOG SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043;vesicle fusion#GO:0006906 membrane#GO:0016020;membrane protein complex#GO:0098796;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 SNARE protein#PC00034 DROME|FlyBase=FBgn0052758|UniProtKB=Q9W486 Q9W486 Snx27 PTHR12431:SF19 SORTING NEXIN 17 AND 27 SORTING NEXIN-27 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;macromolecule metabolic process#GO:0043170;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035541|UniProtKB=Q9VZC8 Q9VZC8 Dmel\CG15019 PTHR34253:SF1 PROTEIN LLP HOMOLOG PROTEIN LLP HOMOLOG animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;developmental cell growth#GO:0048588;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;developmental process#GO:0032502;neuron differentiation#GO:0030182;developmental growth#GO:0048589;cell growth#GO:0016049;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0029994|UniProtKB=Q9W3K9 Q9W3K9 Ldsdh1 PTHR24322:SF754 PKSB SHORT-CHAIN DEHYDROGENASE_REDUCTASE 3 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811 dehydrogenase#PC00092 DROME|FlyBase=FBgn0031036|UniProtKB=Q9VWG2 Q9VWG2 SDS3 PTHR21964:SF34 BREAST CANCER METASTASIS-SUPPRESSOR 1 SIN3 HISTONE DEACETYLASE COREPRESSOR COMPLEX COMPONENT SDS3 enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;histone deacetylase binding#GO:0042826 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 DROME|FlyBase=FBgn0031442|UniProtKB=Q8T8U1 Q8T8U1 Prosbeta4R1 PTHR11599:SF6 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-2 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0261261|UniProtKB=E1JJ52 E1JJ52 plx PTHR22957:SF653 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN FI17814P1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0086253|UniProtKB=Q8T045 Q8T045 rumi PTHR12203:SF126 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 1 glucosyltransferase activity#GO:0046527;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;UDP-xylosyltransferase activity#GO:0035252;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;carbohydrate derivative metabolic process#GO:1901135;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;positive regulation of Notch signaling pathway#GO:0045747;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0260944|UniProtKB=Q02427 Q02427 Rbp1 PTHR23147:SF75 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 1-RELATED membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;nuclear speck#GO:0016607;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0038716|UniProtKB=Q9VDV9 Q9VDV9 Dmel\CG7342 PTHR24064:SF467 SOLUTE CARRIER FAMILY 22 MEMBER FI01439P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0036090|UniProtKB=Q8T0B1 Q8T0B1 Cnep1r2 PTHR20996:SF1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 phosphatase modulator#PC00184 DROME|FlyBase=FBgn0028978|UniProtKB=Q9V3Z1 Q9V3Z1 trbl PTHR22961:SF13 SER/THR PROTEIN KINASE-TRB TRIBBLES enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of proteasomal protein catabolic process#GO:1901800 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0037439|UniProtKB=Q9VI15 Q9VI15 Dmel\CG10286 PTHR13347:SF1 HEAT REPEAT-CONTAINING PROTEIN 3 HEAT REPEAT-CONTAINING PROTEIN 3 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;ribonucleoprotein complex biogenesis#GO:0022613;protein localization to organelle#GO:0033365;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273 DROME|FlyBase=FBgn0052404|UniProtKB=Q9VRU7 Q9VRU7 Cpr65Aw PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0039742|UniProtKB=Q9VAB0 Q9VAB0 Dmel\CG15528 PTHR45961:SF6 IP21249P IP21249P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 Oxidative stress response#P00046>MKP5#P01131 DROME|FlyBase=FBgn0038590|UniProtKB=Q9VEA6 Q9VEA6 Dmel\CG12320 PTHR12689:SF4 A1 CISTRON SPLICING FACTOR AAR2-RELATED PROTEIN AAR2 HOMOLOG nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0028546|UniProtKB=Q9V428 Q9V428 ics PTHR45752:SF215 LEUCINE-RICH REPEAT-CONTAINING GH17740P-RELATED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0029105|UniProtKB=A0A0C4DHD7 A0A0C4DHD7 alpha-Catr PTHR46342:SF1 ALPHA-CATULIN ALPHA-CATULIN intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 Wnt signaling pathway#P00057>alpha-catenin#P01471 DROME|FlyBase=FBgn0035481|UniProtKB=Q29R14 Q29R14 scrape PTHR23226:SF139 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER X-CHROMOSOMAL PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0036980|UniProtKB=M9PG08 M9PG08 RhoBTB PTHR24072:SF156 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN CONTAINING, ISOFORM B hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;signaling#GO:0023052;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell shape#GO:0008360;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;establishment or maintenance of cell polarity#GO:0007163 membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0043070|UniProtKB=Q9GU50 Q9GU50 MESK2 PTHR11034:SF62 N-MYC DOWNSTREAM REGULATED GH09802P signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 serine protease#PC00203 DROME|FlyBase=FBgn0035873|UniProtKB=Q9VSH5 Q9VSH5 Dmel\CG13670 PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0266696|UniProtKB=X2JAM4 X2JAM4 Svil PTHR11977:SF143 VILLIN SUPERVILLIN, ISOFORM AE phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167 actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0016762|UniProtKB=Q24239 Q24239 angel PTHR12121:SF105 CARBON CATABOLITE REPRESSOR PROTEIN 4 PROTEIN ANGEL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;mRNA 3'-UTR binding#GO:0003730;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;mRNA binding#GO:0003729;exonuclease activity#GO:0004527;binding#GO:0005488;3'-5'-RNA exonuclease activity#GO:0000175;nuclease activity#GO:0004518 regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;mitochondrial RNA 3'-end processing#GO:0000965;RNA processing#GO:0006396;RNA destabilization#GO:0050779;mRNA processing#GO:0006397;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;negative regulation of macromolecule biosynthetic process#GO:0010558;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of gene expression#GO:0010468;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;mitochondrial RNA processing#GO:0000963 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0053795|UniProtKB=Q4ABJ4 Q4ABJ4 Dmel\CG33795 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0034251|UniProtKB=A1ZAW7 A1ZAW7 ND-51L1 PTHR11780:SF10 NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1 NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 oxidoreductase#PC00176 DROME|FlyBase=FBgn0003475|UniProtKB=Q9U1K1 Q9U1K1 spir PTHR21345:SF3 SPIRE PROTEIN SPIRE protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;membrane invagination#GO:0010324;meiotic cell cycle#GO:0051321;gamete generation#GO:0007276;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cellular localization#GO:0051641;spindle localization#GO:0051653;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;nuclear division#GO:0000280;membrane organization#GO:0061024;establishment of spindle localization#GO:0051293;actin filament organization#GO:0007015;establishment of localization#GO:0051234;meiotic nuclear division#GO:0140013;transport#GO:0006810;intracellular transport#GO:0046907;reproductive process#GO:0022414;actin cytoskeleton organization#GO:0030036;cell division#GO:0051301;cell cycle#GO:0007049;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;actin filament-based process#GO:0030029;sexual reproduction#GO:0019953;organelle localization#GO:0051640 vesicle#GO:0031982;cell cortex#GO:0005938;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;organelle membrane#GO:0031090 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0003145|UniProtKB=P06601 P06601 prd PTHR45636:SF49 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED SEGMENTATION PROTEIN PAIRED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0030891|UniProtKB=M9PHZ1 M9PHZ1 Ada3 PTHR13556:SF2 TRANSCRIPTIONAL ADAPTER 3-RELATED TRANSCRIPTIONAL ADAPTER 3 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0040475|UniProtKB=Q9NCC3 Q9NCC3 SH3PX1 PTHR45827:SF1 SORTING NEXIN SORTING NEXIN ion binding#GO:0043167;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;anion binding#GO:0043168 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular localization#GO:0051641;localization#GO:0051179;plasma membrane organization#GO:0007009;cellular component organization#GO:0016043;endocytosis#GO:0006897 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0250908|UniProtKB=Q9VBC9 Q9VBC9 beat-VII PTHR21261:SF3 BEAT PROTEIN BEATEN PATH VII intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0024920|UniProtKB=O76511 O76511 Ts PTHR11548:SF2 THYMIDYLATE SYNTHASE 1 THYMIDYLATE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 Formyltetrahydrofolate biosynthesis#P02743>Thymidylate synthase#P02954;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>Thymidylate synthase#P02913;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957 DROME|FlyBase=FBgn0051015|UniProtKB=Q8T5S8 Q8T5S8 PH4alphaPV PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036761|UniProtKB=Q9VVL6 Q9VVL6 MED19 PTHR22536:SF1 LUNG CANCER METASTASIS-RELATED LCMR1 PROTEIN MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557 membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DROME|FlyBase=FBgn0033557|UniProtKB=Q5U0X8 Q5U0X8 Dmel\CG12325 PTHR19858:SF0 WD40 REPEAT PROTEIN PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0267428|UniProtKB=Q7PLL7 Q7PLL7 DIP-lambda PTHR12231:SF87 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN BETA, ISOFORM C-RELATED cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular process#GO:0009987 neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell junction#GO:0030054;cell projection membrane#GO:0031253;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0288690|UniProtKB=Q8IRL9 Q8IRL9 Dna2 PTHR10887:SF433 DNA2/NAM7 HELICASE FAMILY DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2 endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 DNA replication#P00017>Hel#P00532 DROME|FlyBase=FBgn0031466|UniProtKB=Q9VQH4 Q9VQH4 dC1GalT7 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 transferase#PC00220 DROME|Gene_ORFName=Dmel_CG3318|UniProtKB=A0ACD4DAR7 A0ACD4DAR7 speck PTHR20905:SF33 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0266801|UniProtKB=Q9VHR2 Q9VHR2 CG42286 PTHR11640:SF154 NEPHRIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0037386|UniProtKB=A8JQU1 A8JQU1 Dmel\CG1208 PTHR48021:SF86 FAMILY NOT NAMED FACILITATED TREHALOSE TRANSPORTER TRET1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0040347|UniProtKB=Q9V3T1 Q9V3T1 mus81 PTHR13451:SF0 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT MUS81 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 cell communication#GO:0007154;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;mitotic cell cycle process#GO:1903047;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA integrity checkpoint signaling#GO:0031570;double-strand break repair via break-induced replication#GO:0000727;resolution of meiotic recombination intermediates#GO:0000712;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;meiosis I#GO:0007127;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0038533|UniProtKB=Q9VEH2 Q9VEH2 Dmel\CG7523 PTHR31592:SF1 TRANSMEMBRANE PROTEIN 192 TRANSMEMBRANE PROTEIN 192 lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 DROME|FlyBase=FBgn0033050|UniProtKB=Q7KRR5 Q7KRR5 Pngl PTHR12143:SF45 PEPTIDE N-GLYCANASE PNGASE -RELATED PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;glycoprotein metabolic process#GO:0009100;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of BMP signaling pathway#GO:0030513;macromolecule metabolic process#GO:0043170;carbohydrate derivative metabolic process#GO:1901135;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of response to stimulus#GO:0048584 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 DROME|FlyBase=FBgn0037338|UniProtKB=Q9VND2 Q9VND2 Snm1 PTHR23240:SF6 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED DNA CROSS-LINK REPAIR 1A PROTEIN DNA binding#GO:0003677;hydrolase activity#GO:0016787;5'-3' exonuclease activity#GO:0008409;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;exonuclease activity#GO:0004527;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;damaged DNA binding#GO:0003684 cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0038745|UniProtKB=A0A0B4LID7 A0A0B4LID7 ClpX PTHR48102:SF7 ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED ATP-DEPENDENT CLPX-LIKE CHAPERONE, MITOCHONDRIAL purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190 DROME|FlyBase=FBgn0030586|UniProtKB=Q8SXY8 Q8SXY8 Dmel\CG12539 PTHR11552:SF208 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE RE36204P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0023174|UniProtKB=Q9VUJ1 Q9VUJ1 Prosbeta2 PTHR11599:SF44 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0039026|UniProtKB=Q86B80 Q86B80 Dmel\CG7029 PTHR14445:SF36 GRB10 INTERACTING GYF PROTEIN FI03272P-RELATED translation regulator activity#GO:0045182 negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0264753|UniProtKB=A1ZBJ6 A1ZBJ6 Rgk1 PTHR45775:SF7 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C RAD, GEM_KIR FAMILY MEMBER 1, ISOFORM B ribonucleotide binding#GO:0032553;calcium channel regulator activity#GO:0005246;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ion channel regulator activity#GO:0099106;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;channel regulator activity#GO:0016247 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0030086|UniProtKB=Q9W392 Q9W392 CCT2 PTHR11353:SF23 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT BETA metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperonin#PC00073 DROME|FlyBase=FBgn0039165|UniProtKB=Q9VCB7 Q9VCB7 GH20028p PTHR10887:SF341 DNA2/NAM7 HELICASE FAMILY NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase complex#GO:0030880 RNA helicase#PC00032 DROME|FlyBase=FBgn0033520|UniProtKB=A1Z892 A1Z892 Prx6b PTHR43503:SF3 MCG48959-RELATED 1-CYS PEROXIREDOXIN antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;peroxidase#PC00180 DROME|FlyBase=FBgn0022338|UniProtKB=Q9XZT6 Q9XZT6 dnk PTHR10513:SF24 DEOXYNUCLEOSIDE KINASE THYMIDINE KINASE 2, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;deoxynucleoside kinase activity#GO:0019136;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 DROME|FlyBase=FBgn0039612|UniProtKB=Q9VAS1 Q9VAS1 Nepl19 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0052163|UniProtKB=Q8IQP3 Q8IQP3 Dmel\CG32163 PTHR31435:SF9 PROTEIN NATD1 PROTEIN NATD1 DROME|FlyBase=FBgn0262619|UniProtKB=Q9W1H4 Q9W1H4 DNAlig1 PTHR45674:SF15 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 1 catalytic activity, acting on DNA#GO:0140097;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;mitotic cell cycle#GO:0000278;DNA strand elongation involved in DNA replication#GO:0006271;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;DNA replication#GO:0006260;cell cycle process#GO:0022402;DNA-templated DNA replication#GO:0006261 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA ligase#PC00012;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0260940|UniProtKB=Q9VD72 Q9VD72 lsn PTHR12806:SF0 EAP30 SUBUNIT OF ELL COMPLEX VACUOLAR-SORTING PROTEIN SNF8 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein transport#GO:0015031;cellular localization#GO:0051641;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization to vacuole#GO:0072666;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to vacuole#GO:0072665;localization#GO:0051179;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;macromolecule localization#GO:0033036;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0038593|UniProtKB=Q9VEA2 Q9VEA2 Vps39 PTHR12894:SF49 CNH DOMAIN CONTAINING VAM6_VPS39-LIKE PROTEIN binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267 cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;vacuole fusion#GO:0097576;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular component disassembly#GO:0022411;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;macroautophagy#GO:0016236;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;transport#GO:0006810;metabolic process#GO:0008152;autophagosome maturation#GO:0097352;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle tethering complex#GO:0099023;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0037829|UniProtKB=Q9VGX7 Q9VGX7 Dmel\CG14691 PTHR23511:SF36 SYNAPTIC VESICLE GLYCOPROTEIN 2 EG:BACR7A4.13 PROTEIN-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0027844|UniProtKB=Q9V396 Q9V396 CAH1 PTHR18952:SF141 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0085420|UniProtKB=A8JNC7 A8JNC7 DIP-delta PTHR12231:SF247 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN DELTA, ISOFORM D protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 cellular process#GO:0009987;synapse organization#GO:0050808;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253;cell junction#GO:0030054 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0040524|UniProtKB=Q9VHX3 Q9VHX3 Dmel\CG11052 PTHR10029:SF3 ACYLPHOSPHATASE ACYLPHOSPHATASE-1 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 DROME|FlyBase=FBgn0030015|UniProtKB=Q9W3I6 Q9W3I6 Dmel\CG10761 PTHR46283:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;metabolic process#GO:0008152;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0003502|UniProtKB=P08630 P08630 Btk PTHR24418:SF479 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BTK catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;non-membrane spanning protein tyrosine kinase activity#GO:0004715 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 DROME|FlyBase=FBgn0266136|UniProtKB=Q7JQ32 Q7JQ32 Gyc76C PTHR11920:SF474 GUANYLYL CYCLASE GUANYLATE CYCLASE-RELATED molecular transducer activity#GO:0060089;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653 ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanylate cyclase#PC00114;lyase#PC00144 DROME|FlyBase=FBgn0039580|UniProtKB=Q9VAW3 Q9VAW3 Gfat2 PTHR10937:SF0 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING) catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;nucleoside phosphate metabolic process#GO:0006753;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 DROME|FlyBase=FBgn0038507|UniProtKB=Q9VEK3 Q9VEK3 Dmel\CG5863 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;primary metabolic process#GO:0044238;programmed cell death#GO:0012501 protease#PC00190;aspartic protease#PC00053 DROME|FlyBase=FBgn0031753|UniProtKB=Q9VMK8 Q9VMK8 Dmel\CG13999 PTHR13306:SF6 TRANSMEMBRANE PROTEIN 138 TRANSMEMBRANE PROTEIN 138 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 DROME|FlyBase=FBgn0261641|UniProtKB=A0A0B4KFB8 A0A0B4KFB8 CG31367 PTHR15377:SF3 TRANSCRIPTION ELONGATION REGULATOR 1 WW DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;RNA polymerase binding#GO:0070063;binding#GO:0005488;transcription coregulator activity#GO:0003712 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 general transcription factor#PC00259 DROME|FlyBase=FBgn0031800|UniProtKB=Q9VMF1 Q9VMF1 Dmel\CG9497 PTHR11012:SF56 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0000057|UniProtKB=Q7K7W5 Q7K7W5 adp PTHR15574:SF40 WD REPEAT DOMAIN-CONTAINING FAMILY WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1 regulation of lipid biosynthetic process#GO:0046890;regulation of cellular process#GO:0050794;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0035947|UniProtKB=Q9VSS2 Q9VSS2 Srp68 PTHR12860:SF0 SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614 ribonucleoprotein complex#GO:1990904;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0013269|UniProtKB=P54397 P54397 Fkbp39 PTHR43811:SF63 FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA 39 KDA FK506-BINDING NUCLEAR PROTEIN peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0039771|UniProtKB=Q9VA75 Q9VA75 Osi23 PTHR21879:SF8 FI03362P-RELATED-RELATED OSIRIS 23 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028342|UniProtKB=Q9W2X6 Q9W2X6 ATPsyndelta PTHR13822:SF7 ATP SYNTHASE DELTA/EPSILON CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT DELTA, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034 proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 DROME|FlyBase=FBgn0038542|UniProtKB=Q9VEG1 Q9VEG1 TyrR PTHR24248:SF207 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR IP13425P-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0004864|UniProtKB=Q24592 Q24592 hop PTHR45807:SF7 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE HOPSCOTCH non-receptor tyrosine protein kinase#PC00168 DROME|FlyBase=FBgn0030163|UniProtKB=Q9W302 Q9W302 AAF46535 PTHR19143:SF470 FIBRINOGEN/TENASCIN/ANGIOPOEITIN GH05177P-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0033134|UniProtKB=Q7K527 Q7K527 Tsp42El PTHR19282:SF521 TETRASPANIN AT12771P-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0029887|UniProtKB=Q9W3X8 Q9W3X8 Dmel\CG3198 PTHR12375:SF47 RNA-BINDING PROTEIN LUC7-RELATED LUC7-LIKE PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site recognition#GO:0006376;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;spliceosomal complex#GO:0005681 DROME|FlyBase=FBgn0029915|UniProtKB=X2JAQ5 X2JAQ5 Dmel\CG14434 PTHR21028:SF2 SI:CH211-156B7.4 CYTH DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0053497|UniProtKB=Q7KWG3 Q7KWG3 Sdic2 PTHR12442:SF22 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED protein binding#GO:0005515;binding#GO:0005488 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;microtubule-based movement#GO:0007018;cytoskeleton-dependent intracellular transport#GO:0030705;intracellular transport#GO:0046907;microtubule-based transport#GO:0099111;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular localization#GO:0051641;microtubule-based process#GO:0007017 dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0031258|UniProtKB=Q9VPQ4 Q9VPQ4 Dmel\CG4297 PTHR23246:SF13 NEW-GLUE PROTEIN GH12359P DROME|FlyBase=FBgn0040308|UniProtKB=Q9V3Q4 Q9V3Q4 Prx4 PTHR10681:SF180 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular process#GO:0009987;response to stress#GO:0006950;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;response to oxidative stress#GO:0006979;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 peroxidase#PC00180;oxidoreductase#PC00176 DROME|FlyBase=FBgn0284253|UniProtKB=Q9VQR8 Q9VQR8 LeuRS PTHR45794:SF1 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0010238|UniProtKB=Q24372 Q24372 Lac PTHR12231:SF220 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN LACHESIN binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0024985|UniProtKB=O76878 O76878 Rilpl PTHR21502:SF4 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN HOMOLOG enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0263072|UniProtKB=B7Z141 B7Z141 CG9817 PTHR24391:SF18 HISTONE H4 TRANSCRIPTION FACTOR-RELATED SECRETED PROTEIN gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0030026|UniProtKB=Q9W3H4 Q9W3H4 sni PTHR43544:SF41 SHORT-CHAIN DEHYDROGENASE/REDUCTASE LD36273P alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 DROME|FlyBase=FBgn0030974|UniProtKB=Q9VWN4 Q9VWN4 Flacc PTHR38563:SF1 FL(2)D-ASSOCIATED COMPLEX COMPONENT FL(2)D-ASSOCIATED COMPLEX COMPONENT DROME|FlyBase=FBgn0034129|UniProtKB=A1ZAG4 A1ZAG4 Parp16 PTHR21328:SF2 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP16 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;enzyme binding#GO:0019899;kinase activator activity#GO:0019209;kinase binding#GO:0019900;binding#GO:0005488 intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950 organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783 DROME|FlyBase=FBgn0032664|UniProtKB=Q9VJA5 Q9VJA5 Slc25A46b PTHR21252:SF3 TB1 PROTEIN-RELATED FI08023P-RELATED organelle fission#GO:0048285;mitochondrial fission#GO:0000266;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0000479|UniProtKB=Q9W4T4 Q9W4T4 dnc PTHR11347:SF198 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE, ISOFORM I cyclic-nucleotide phosphodiesterase activity#GO:0004112;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 phosphodiesterase#PC00185;hydrolase#PC00121 DROME|FlyBase=FBgn0032475|UniProtKB=Q9VK33 Q9VK33 Sfmbt PTHR12247:SF104 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SFMBT histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0261873|UniProtKB=E2QD98 E2QD98 sdt PTHR23122:SF14 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS1 establishment or maintenance of apical/basal cell polarity#GO:0035088;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of bipolar cell polarity#GO:0061245;generation of neurons#GO:0048699;localization within membrane#GO:0051668;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;tissue morphogenesis#GO:0048729;system development#GO:0048731;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;protein localization to cell periphery#GO:1990778;developmental process#GO:0032502;cellular developmental process#GO:0048869;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;morphogenesis of an epithelium#GO:0002009;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;nervous system development#GO:0007399;embryo development#GO:0009790 cell junction#GO:0030054;adherens junction#GO:0005912;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0034866|UniProtKB=Q9W1P7 Q9W1P7 Or59c PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030738|UniProtKB=A8JV07 A8JV07 Dmel\CG9915 PTHR46010:SF1 PROTEIN IWS1 HOMOLOG PROTEIN IWS1 HOMOLOG nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;localization#GO:0051179;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034440|UniProtKB=A0A0B4KFC9 A0A0B4KFC9 Dmel\CG10073 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0002526|UniProtKB=Q00174 Q00174 LanA PTHR10574:SF449 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 DROME|FlyBase=FBgn0035753|UniProtKB=Q9VS34 Q9VS34 RpL18 PTHR10934:SF2 60S RIBOSOMAL PROTEIN L18 LARGE RIBOSOMAL SUBUNIT PROTEIN EL18 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0260766|UniProtKB=Q9VI17 Q9VI17 Dmel\CG42564 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0261930|UniProtKB=P22808 P22808 vnd PTHR24340:SF82 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN VND sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0035852|UniProtKB=Q8SZX1 Q8SZX1 Dmel\CG7387 PTHR44145:SF5 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG L(2)TID, MITOCHONDRIAL organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 DROME|FlyBase=FBgn0038742|UniProtKB=Q9VDT1 Q9VDT1 Arc42 PTHR43884:SF42 ACYL-COA DEHYDROGENASE SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;short-chain fatty acid catabolic process#GO:0019626;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0261535|UniProtKB=Q9V3P2 Q9V3P2 l(2)34Fd PTHR14927:SF0 NUCLEOLAR PROTEIN 10 NUCLEOLAR PROTEIN 10 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0260237|UniProtKB=E1JIG6 E1JIG6 BBIP1 PTHR28596:SF1 BBSOME-INTERACTING PROTEIN 1 BBSOME-INTERACTING PROTEIN 1 cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;localization within membrane#GO:0051668 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;BBSome#GO:0034464;plasma membrane region#GO:0098590;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227 DROME|Gene_ORFName=Dmel_CG30424|UniProtKB=A0ACA5W0V3 A0ACA5W0V3 cGlr2 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED nucleotidyltransferase#PC00174;transferase#PC00220 DROME|FlyBase=FBgn0037779|UniProtKB=Q9VH37 Q9VH37 Dmel\CG12811 PTHR21177:SF4 IP06524P-RELATED IP06524P DROME|FlyBase=FBgn0033115|UniProtKB=Q8SZF4 Q8SZF4 Spn42De PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0263109|UniProtKB=A1Z6I3 A1Z6I3 Dmel\CG43366 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0004957|UniProtKB=Q9VWV9 Q9VWV9 por PTHR13906:SF12 PORCUPINE PROTEIN-SERINE O-PALMITOLEOYLTRANSFERASE PORCUPINE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;acyltransferase activity#GO:0016746;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;protein localization to extracellular region#GO:0071692;regulation of biological process#GO:0050789;signaling#GO:0023052;export from cell#GO:0140352;signal release#GO:0023061;secretion#GO:0046903;protein secretion#GO:0009306;cell communication#GO:0007154;localization#GO:0051179;protein transport#GO:0015031;secretion by cell#GO:0032940;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;transport#GO:0006810;lipid metabolic process#GO:0006629;establishment of localization#GO:0051234;lipid modification#GO:0030258;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acetyltransferase#PC00038 DROME|FlyBase=FBgn0037150|UniProtKB=Q9VNW1 Q9VNW1 Dmel\CG7133 PTHR24074:SF61 CO-CHAPERONE PROTEIN DJLA DNAJ HOMOLOG SUBFAMILY B MEMBER 9 chaperone#PC00072 DROME|FlyBase=FBgn0016031|UniProtKB=Q9VRK8 Q9VRK8 lama PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 DROME|FlyBase=FBgn0004449|UniProtKB=O61307 O61307 Ten-m PTHR11219:SF72 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-M binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;synaptic membrane adhesion#GO:0099560;axonogenesis#GO:0007409;neuron development#GO:0048666;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cell junction organization#GO:0034330;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cell junction#GO:0030054 DROME|FlyBase=FBgn0086683|UniProtKB=Q7PL83 Q7PL83 Spf45 PTHR13288:SF9 SPLICING FACTOR 45 SPF45 SPLICING FACTOR 45 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0034022|UniProtKB=Q29QW0 Q29QW0 Dmel\CG12964 PTHR15708:SF15 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED IP14311P lipid binding#GO:0008289;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;phospholipid binding#GO:0005543;binding#GO:0005488 membrane organization#GO:0061024;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0050424|UniProtKB=A8DYP7 A8DYP7 cGlr2 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED transferase#PC00220;nucleotidyltransferase#PC00174 DROME|FlyBase=FBgn0035121|UniProtKB=Q9W0S7 Q9W0S7 Tudor-SN PTHR12302:SF2 EBNA2 BINDING PROTEIN P100 STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1 nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0040235|UniProtKB=Q9V3B6 Q9V3B6 c12.1 PTHR12718:SF2 CELL CYCLE CONTROL PROTEIN CWF15 SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 DROME|FlyBase=FBgn0033856|UniProtKB=A1Z9F8 A1Z9F8 NEST:bs27e02 PTHR43128:SF34 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0067779|UniProtKB=Q9V474 Q9V474 dbr PTHR39942:SF1 BCDNA.LD26519-RELATED BCDNA.LD26519-RELATED DROME|FlyBase=FBgn0034098|UniProtKB=A1ZAC4 A1ZAC4 krimp PTHR22948:SF80 TUDOR DOMAIN CONTAINING PROTEIN KRIMPER FIRST TUDOR DOMAIN-CONTAINING PROTEIN-RELATED scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031039|UniProtKB=Q9VWG0 Q9VWG0 Shawn PTHR45760:SF2 FI19922P1-RELATED FI19922P1-RELATED intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0033449|UniProtKB=Q4V6W8 Q4V6W8 Dmel\CG1663 PTHR24393:SF138 ZINC FINGER PROTEIN IP01201P-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0030893|UniProtKB=X2JCF3 X2JCF3 RhoGAP16F PTHR23176:SF145 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 DROME|FlyBase=FBgn0036258|UniProtKB=Q9VTU4 Q9VTU4 eIF3l PTHR13242:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 DROME|FlyBase=FBgn0263390|UniProtKB=A0A0B4K6G5 A0A0B4K6G5 Nha2 PTHR31102:SF1 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 9 MEMBER B2 DROME|FlyBase=FBgn0030955|UniProtKB=Q9VWQ7 Q9VWQ7 Dmel\CG6891 PTHR10829:SF25 CORTACTIN AND DREBRIN COACTOSIN-LIKE PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament polymerization#GO:0030833;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832 actin filament#GO:0005884;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0031048|UniProtKB=Q9VWF0 Q9VWF0 Dmel\CG12237 PTHR20889:SF12 PHOSPHATASE, ORPHAN 1, 2 LP01149P hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0037657|UniProtKB=Q9VHI1 Q9VHI1 hyx PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0032208|UniProtKB=Q9VL06 Q9VL06 Ufd4 PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE HECTD1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0040805|UniProtKB=A8JNT1 A8JNT1 Dmel\CG12355 PTHR11266:SF85 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0001125|UniProtKB=Q8IPY3 Q8IPY3 Got2 PTHR11879:SF58 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 DROME|FlyBase=FBgn0040338|UniProtKB=Q9W5B9 Q9W5B9 TfIIA-S-2 PTHR10966:SF0 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 transcription factor binding#GO:0008134;binding#GO:0005488;protein binding#GO:0005515 gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 DROME|FlyBase=FBgn0036702|UniProtKB=Q8T4G5 Q8T4G5 Afg3l2 PTHR43655:SF2 ATP-DEPENDENT PROTEASE AFG3 LIKE MATRIX AAA PEPTIDASE SUBUNIT 2, ISOFORM A metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0283510|UniProtKB=Q9V5E1 Q9V5E1 Pal1 PTHR10680:SF44 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYL-ALPHA-HYDROXYGLYCINE ALPHA-AMIDATING LYASE 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 DROME|FlyBase=FBgn0027094|UniProtKB=Q9VLM8 Q9VLM8 AlaRS PTHR11777:SF9 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;ligase activity#GO:0016874;deacylase activity#GO:0160215;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0030693|UniProtKB=Q9VXP1 Q9VXP1 sordd1 PTHR12313:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0052602|UniProtKB=Q8IR52 Q8IR52 Muc12Ea PTHR35383:SF2 MUCIN 12EA-RELATED MUCIN 12EA DROME|FlyBase=FBgn0016701|UniProtKB=Q7KY04 Q7KY04 Rab4 PTHR47979:SF139 DRAB11-RELATED SMALL MONOMERIC GTPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265 transport#GO:0006810;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;recycling endosome#GO:0055037 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0036733|UniProtKB=Q9VVI0 Q9VVI0 U4-U6-60K PTHR19846:SF0 WD40 REPEAT PROTEIN U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP4 RNA processing factor#PC00147;RNA splicing factor#PC00148 mRNA splicing#P00058>U6#P01473;mRNA splicing#P00058>U4#P01476 DROME|FlyBase=FBgn0039250|UniProtKB=Q9VC08 Q9VC08 Mink PTHR15874:SF1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 establishment of spindle localization#GO:0051293;mitotic sister chromatid segregation#GO:0000070;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell division#GO:0051301;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;localization#GO:0051179;organelle localization#GO:0051640;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;spindle localization#GO:0051653;cellular localization#GO:0051641;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;nuclear division#GO:0000280 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 DROME|FlyBase=FBgn0031115|UniProtKB=Q9VRA1 Q9VRA1 Dmel\CG11710 PTHR12963:SF4 THYROID RECEPTOR INTERACTING PROTEIN RELATED TRIP4_RQT4 C2HC5-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;protein biosynthetic process#GO:0160307;modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;translational elongation#GO:0006414;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 protein-containing complex#GO:0032991 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0027360|UniProtKB=Q9W2D6 Q9W2D6 Tim10 PTHR11038:SF16 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 cellular component organization#GO:0016043;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular localization#GO:0051641;organelle organization#GO:0006996;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;protein insertion into mitochondrial inner membrane#GO:0045039;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;mitochondrial protein import pathway#GO:7770058;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;membrane-bounded organelle#GO:0043227 transporter#PC00227 DROME|FlyBase=FBgn0262512|UniProtKB=Q24583 Q24583 Vha14-1 PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0019938|UniProtKB=P91875 P91875 RpI1 PTHR19376:SF11 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1 macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription by RNA polymerase I#GO:0006360;rRNA transcription#GO:0009303;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0028737|UniProtKB=O96827 O96827 eEF1beta PTHR11595:SF92 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-BETA guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 DROME|FlyBase=FBgn0288857|UniProtKB=Q9XZF0 Q9XZF0 Ype PTHR13848:SF56 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 5 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0026141|UniProtKB=O96860 O96860 Cdlc2 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC-RELATED binding#GO:0005488;protein binding#GO:0005515 microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0000566|UniProtKB=Q7JXZ2 Q7JXZ2 Cth PTHR11808:SF15 TRANS-SULFURATION ENZYME FAMILY MEMBER CYSTATHIONINE GAMMA-LYASE catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829 sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;homocysteine metabolic process#GO:0050667;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;metabolite interconversion enzyme#PC00262 Methionine biosynthesis#P02753>O-Succinyl homoserine lyase#P03026 DROME|FlyBase=FBgn0266570|UniProtKB=Q7K4H4 Q7K4H4 NO66 PTHR13096:SF8 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 1 dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993;protein demethylase activity#GO:0140457;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DROME|FlyBase=FBgn0038732|UniProtKB=Q9VDU2 Q9VDU2 Acsx2 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;lipid metabolic process#GO:0006629;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 ligase#PC00142 DROME|FlyBase=FBgn0040342|UniProtKB=Q9V3E0 Q9V3E0 Dmel\CG3706 PTHR34717:SF1 EG:BACR7A4.20 PROTEIN EG:BACR7A4.20 PROTEIN DROME|FlyBase=FBgn0263133|UniProtKB=Q9VM33 Q9VM33 mEFG1 PTHR43636:SF2 ELONGATION FACTOR G, MITOCHONDRIAL ELONGATION FACTOR G, MITOCHONDRIAL ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031412|UniProtKB=Q9VQA7 Q9VQA7 Dmel\CG16995 PTHR10334:SF565 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0262975|UniProtKB=P20482 P20482 cnc PTHR24411:SF55 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR SEGMENTATION PROTEIN CAP'N'COLLAR transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0029830|UniProtKB=Q9W450 Q9W450 Grip PTHR46227:SF2 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP FI03335P protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;endocytic recycling#GO:0032456;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;protein localization to cell junction#GO:1902414;regulation of biological quality#GO:0065008;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;endosome to plasma membrane protein transport#GO:0099638;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein localization to cell periphery#GO:1990778;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;protein localization to synapse#GO:0035418 DROME|FlyBase=FBgn0038416|UniProtKB=Q9VEW7 Q9VEW7 Dmel\CG17930 PTHR23529:SF2 GH19118P-RELATED GH19118P-RELATED DROME|FlyBase=FBgn0011774|UniProtKB=Q23976 Q23976 Irbp PTHR12604:SF2 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU70 telomeric repeat DNA binding#GO:0042162;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA helicase#PC00011 DROME|FlyBase=FBgn0003062|UniProtKB=Q9W1V3 Q9W1V3 Fib PTHR10335:SF28 RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN RRNA 2'-O-METHYLTRANSFERASE FIBRILLARIN histone methyltransferase activity#GO:0042054;binding#GO:0005488;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;N-methyltransferase activity#GO:0008170;nucleic acid binding#GO:0003676;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;RNA binding#GO:0003723;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on a protein#GO:0140096 nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA processing factor#PC00147 DROME|FlyBase=FBgn0015618|UniProtKB=Q9VT57 Q9VT57 Cdk8 PTHR24056:SF581 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 8 cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;protein kinase complex#GO:1902911;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0035348|UniProtKB=M9PE19 M9PE19 CG16760 PTHR11904:SF9 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 glycosyl compound catabolic process#GO:1901658;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside metabolic process#GO:0042278;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;nucleoside catabolic process#GO:0009164;nucleotide biosynthetic process#GO:0009165 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 kinase#PC00137;nucleotide kinase#PC00172 Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250 DROME|FlyBase=FBgn0035170|UniProtKB=Q9W0L9 Q9W0L9 dpr20 PTHR23279:SF3 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 14, ISOFORM A-RELATED cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 DROME|FlyBase=FBgn0032812|UniProtKB=M9PBE2 M9PBE2 Hakai PTHR13480:SF0 E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED E3 UBIQUITIN-PROTEIN LIGASE HAKAI transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0051802|UniProtKB=Q8T415 Q8T415 CG15158 PTHR23050:SF549 CALCIUM BINDING PROTEIN AT22559P metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;centriole replication#GO:0007099;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0046692|UniProtKB=P83098 P83098 Stlk PTHR45832:SF16 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED STE20-RELATED KINASE ADAPTER PROTEIN STLK DROME|FlyBase=FBgn0067628|UniProtKB=Q8INF2 Q8INF2 CG33331 PTHR13619:SF0 PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 organophosphate biosynthetic process#GO:0090407;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0034312|UniProtKB=Q7K1R6 Q7K1R6 Dmel\CG10916 PTHR31649:SF10 AGAP009604-PA IP19903P-RELATED cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0290174|UniProtKB=P54351 P54351 Nsf2 PTHR23078:SF3 VESICULAR-FUSION PROTEIN NSF VESICLE-FUSING ATPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;transport#GO:0006810;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;intra-Golgi vesicle-mediated transport#GO:0006891;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951 Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>NSF#P05774;Ionotropic glutamate receptor pathway#P00037>NSF#P01020 DROME|FlyBase=FBgn0033296|UniProtKB=A1Z7F2 A1Z7F2 Mal-A7 PTHR10357:SF234 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A2-RELATED oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152 amylase#PC00048;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0085419|UniProtKB=A0A0B4LFV4 A0A0B4LFV4 Rgk2 PTHR45775:SF6 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C RAD, GEM_KIR FAMILY MEMBER 2, ISOFORM C DROME|FlyBase=FBgn0039481|UniProtKB=Q9VB81 Q9VB81 Cpr97Eb PTHR10380:SF234 CUTICLE PROTEIN CUTICULAR PROTEIN 97EB extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0051278|UniProtKB=Q9VGY2 Q9VGY2 CG6482 PTHR10458:SF2 PEPTIDE DEFORMYLASE PEPTIDE DEFORMYLASE, MITOCHONDRIAL mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 DROME|FlyBase=FBgn0010406|UniProtKB=Q9VSC3 Q9VSC3 RNaseX25 PTHR11240:SF22 RIBONUCLEASE T2 RIBONUCLEASE X25 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 endoribonuclease#PC00094 DROME|FlyBase=FBgn0031634|UniProtKB=E9NA96 E9NA96 Ir25a PTHR18966:SF411 IONOTROPIC GLUTAMATE RECEPTOR IONOTROPIC RECEPTOR 25A monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0052260|UniProtKB=Q8IRB8 Q8IRB8 BcDNA:GH24648 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0262057|UniProtKB=Q0E8C8 Q0E8C8 Spn77Ba PTHR11461:SF367 SERINE PROTEASE INHIBITOR, SERPIN GH21475P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0022942|UniProtKB=Q7K4N3 Q7K4N3 Cbp80 PTHR12412:SF2 CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0053126|UniProtKB=M9PBN2 M9PBN2 NLaz PTHR10612:SF63 APOLIPOPROTEIN D APOLIPOPROTEIN D cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052 DROME|FlyBase=FBgn0031547|UniProtKB=Q9VQS2 Q9VQS2 Sr-CIV PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED DROME|FlyBase=FBgn0085423|UniProtKB=R9PY62 R9PY62 GramD1B PTHR23319:SF4 GRAM DOMAIN CONTAINING 1B, ISOFORM E AT22714P-RELATED binding#GO:0005488;lipid carrier activity#GO:0005319;sterol binding#GO:0032934;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;steroid binding#GO:0005496 intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;cellular localization#GO:0051641;sterol transport#GO:0015918;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;lipid localization#GO:0010876 endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle membrane contact site#GO:0044232;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 DROME|FlyBase=FBgn0262483|UniProtKB=A0A0B4JDC9 A0A0B4JDC9 Rbp PTHR14234:SF19 RIM BINDING PROTEIN-RELATED RIM-BINDING PROTEIN, ISOFORM F scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035625|UniProtKB=M9PBR0 M9PBR0 Blimp-1 PTHR16515:SF59 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0064117|UniProtKB=Q0KHQ1 Q0KHQ1 SLIRP1 PTHR48024:SF64 GEO13361P1-RELATED GEO13361P1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0005638|UniProtKB=Q02637 Q02637 slbo PTHR23334:SF75 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0051787|UniProtKB=Q8INX8 Q8INX8 p24 PTHR22811:SF59 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN GOLD DOMAIN-CONTAINING PROTEIN-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982 vesicle coat protein#PC00235;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0022935|UniProtKB=Q9VRV5 Q9VRV5 D19A PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0026389|UniProtKB=P81917 P81917 Or43a PTHR21137:SF3 ODORANT RECEPTOR ODORANT RECEPTOR 30A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0260744|UniProtKB=Q9VGF5 Q9VGF5 Tango9 PTHR13146:SF0 SOLUTE CARRIER FAMILY 35 MEMBER F6-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F6 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0045842|UniProtKB=Q9V435 Q9V435 yuri PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular localization#GO:0051641;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;organelle localization#GO:0051640;localization within membrane#GO:0051668;localization#GO:0051179;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;membrane organization#GO:0061024;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;intracellular protein localization#GO:0008104 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 FAS signaling pathway#P00020>Nuclear Lamin#P00616 DROME|FlyBase=FBgn0026392|UniProtKB=P81914 P81914 Or33a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0260855|UniProtKB=M9PGI6 M9PGI6 Sec22 PTHR45837:SF3 VESICLE-TRAFFICKING PROTEIN SEC22B VESICLE-TRAFFICKING PROTEIN SEC22B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;membrane fusion#GO:0061025;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;Golgi organization#GO:0007030 organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vesicle#GO:0031982;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708 DROME|FlyBase=FBgn0033727|UniProtKB=Q9V6A9 Q9V6A9 Or49a PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0053993|UniProtKB=Q6NR09 Q6NR09 Egfrap PTHR45734:SF7 TENSIN EGFR ADAPTER PROTEIN-RELATED anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0050052|UniProtKB=Q7JVM1 Q7JVM1 Obp49a PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0030704|UniProtKB=Q8SXX0 Q8SXX0 BcDNA:RH08992 PTHR14725:SF0 RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED DROME|FlyBase=FBgn0032229|UniProtKB=Q9VKY3 Q9VKY3 ClpP PTHR10381:SF11 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL enzyme binding#GO:0019899;ATP-dependent activity#GO:0140657;serine-type peptidase activity#GO:0008236;binding#GO:0005488;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056 protein-containing complex#GO:0032991;catalytic complex#GO:1902494 serine protease#PC00203 DROME|FlyBase=FBgn0034570|UniProtKB=A0A6M3Q7L9 A0A6M3Q7L9 Dmel\CG10543 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0034560|UniProtKB=Q9W2Q2 Q9W2Q2 CAH15 PTHR18952:SF227 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 13-RELATED hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0030057|UniProtKB=Q9W3C7 Q9W3C7 Ppt1 PTHR11247:SF81 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 PALMITOYL-PROTEIN THIOESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 multicellular organismal process#GO:0032501;endocytosis#GO:0006897;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;transport#GO:0006810;developmental process#GO:0032502;anatomical structure development#GO:0048856;import into cell#GO:0098657;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;localization#GO:0051179;system development#GO:0048731 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038281|UniProtKB=Q9VFE0 Q9VFE0 RpL10Aa PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0039436|UniProtKB=Q9VBE0 Q9VBE0 TwdlB PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 DROME|FlyBase=FBgn0033846|UniProtKB=A1Z9E2 A1Z9E2 mip120 PTHR12446:SF34 TESMIN/TSO1-RELATED PROTEIN LIN-54 HOMOLOG-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031091|UniProtKB=Q9W5W9 Q9W5W9 Phf7 PTHR12420:SF50 PHD FINGER PROTEIN LD43541P-RELATED organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0045761|UniProtKB=Q107I8 Q107I8 CHKov1 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0003249|UniProtKB=P04950 P04950 Rh3 PTHR24240:SF226 OPSIN OPSIN RH3-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signal transduction#GO:0007165;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;detection of stimulus#GO:0051606;biological regulation#GO:0065007;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030869|UniProtKB=M9PHY7 M9PHY7 Socs16D PTHR10155:SF39 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING AT 16D, ISOFORM B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 kinase modulator#PC00140 DROME|FlyBase=FBgn0030061|UniProtKB=Q9W3C2 Q9W3C2 Nop53 PTHR14211:SF7 GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2 RIBOSOME BIOGENESIS PROTEIN NOP53 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0039743|UniProtKB=Q9VAA9 Q9VAA9 Jasper PTHR12550:SF70 HEPATOMA-DERIVED GROWTH FACTOR-RELATED JIL-1 ANCHORING AND STABILIZING PROTEIN, ISOFORM A cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0031108|UniProtKB=Q9VR92 Q9VR92 Dmel\CG15459 PTHR34038:SF1 ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT K, MITOCHONDRIAL membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ATP synthase#PC00002 DROME|FlyBase=FBgn0033581|UniProtKB=Q7K4G8 Q7K4G8 anon-WO0140519.201 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0087005|UniProtKB=Q9VN91 Q9VN91 rtp PTHR46614:SF1 MORN REPEAT-CONTAINING PROTEIN 4 MORN REPEAT-CONTAINING PROTEIN 4 response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611 cell projection#GO:0042995;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038638|UniProtKB=Q9VE49 Q9VE49 Dmel\CG7702 PTHR24364:SF18 LP06937P LP06937P cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0261811|UniProtKB=Q9VWB7 Q9VWB7 pico PTHR11243:SF39 GROWTH FACTOR RECEPTOR-BOUND PROTEIN LD06925P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;signaling#GO:0023052;cell morphogenesis#GO:0000902;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032600|UniProtKB=M9PBC6 M9PBC6 BuGZ PTHR23215:SF0 ZINC FINGER PROTEIN 207 BUB3 INTERACTING GLEBS AND ZINC FINGER DOMAIN PROTEIN, ISOFORM F membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0051016|UniProtKB=Q9VA52 Q9VA52 CG9708 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;oxidoreductase complex#GO:1990204;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032732|UniProtKB=Q9VJ25 Q9VJ25 EMC5 PTHR21181:SF7 ER membrane protein complex subunit 5-related ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 DROME|FlyBase=FBgn0030790|UniProtKB=Q9VXB1 Q9VXB1 Dmel\CG4768 PTHR31624:SF4 UPF0472 PROTEIN C16ORF72 HUWE1 ASSOCIATED PROTEIN MODIFYING STRESS RESPONSES DROME|FlyBase=FBgn0261509|UniProtKB=A0A4D6K327 A0A4D6K327 haf PTHR24366:SF179 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS HATTIFATTENER, ISOFORM I immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0035526|UniProtKB=Q9VZE4 Q9VZE4 cg1316 PTHR10352:SF18 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G RNA BINDING MOTIF PROTEIN 45 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 DROME|FlyBase=FBgn0039749|UniProtKB=A0A1Z1CH18 A0A1Z1CH18 Dmel\CG11498 PTHR21771:SF1 MITOCHONDRIA-EATING PROTEIN-RELATED MITOCHONDRIA-EATING PROTEIN DROME|FlyBase=FBgn0033900|UniProtKB=Q7K3P0 Q7K3P0 CysRS-m PTHR10890:SF27 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0026181|UniProtKB=Q9VXE3 Q9VXE3 Rok PTHR22988:SF73 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cortical cytoskeleton organization#GO:0030865;regulation of cell junction assembly#GO:1901888;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;cortical actin cytoskeleton organization#GO:0030866;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cell division#GO:0051301;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;mitotic cell cycle process#GO:1903047;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cytokinesis#GO:0000910;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;actomyosin structure organization#GO:0031032;signaling#GO:0023052;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;embryo development#GO:0009790;intracellular signaling cassette#GO:0141124;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 DROME|FlyBase=FBgn0025629|UniProtKB=O77263 O77263 Mettl1 PTHR23417:SF16 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 DROME|FlyBase=FBgn0034361|UniProtKB=A1ZBA5 A1ZBA5 mRpS28 PTHR13447:SF2 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN BS1M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543 organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0263235|UniProtKB=Q9VKA8 Q9VKA8 Phae2 PTHR24276:SF99 POLYSERASE-RELATED AT26814P-RELATED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0022943|UniProtKB=Q9V3L6 Q9V3L6 Cbp20 PTHR18847:SF0 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mRNA processing#GO:0006397;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA export from nucleus#GO:0006406;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;macromolecule localization#GO:0033036;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;negative regulation of cellular process#GO:0048523;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions#GO:0000375 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0010309|UniProtKB=Q24118 Q24118 pigeon PTHR13630:SF1 GAMMA-SECRETASE-ACTIVATING PROTEIN GAMMA-SECRETASE-ACTIVATING PROTEIN positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0022288|UniProtKB=Q8SYL1 Q8SYL1 l(2)09851 PTHR45903:SF1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0000044|UniProtKB=P53501 P53501 Act57B PTHR11937:SF397 ACTIN ACTIN-57B-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 DROME|FlyBase=FBgn0037980|UniProtKB=Q9VGE3 Q9VGE3 DCAF12 PTHR19860:SF16 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 DROME|FlyBase=FBgn0030850|UniProtKB=Q9VX39 Q9VX39 stas PTHR43220:SF18 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41B cellular component assembly#GO:0022607;catabolic process#GO:0009056;macroautophagy#GO:0016236;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 DROME|FlyBase=FBgn0025352|UniProtKB=Q9W1H8 Q9W1H8 Mtpbeta PTHR18919:SF153 ACETYL-COA C-ACYLTRANSFERASE TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0036277|UniProtKB=Q9VTW6 Q9VTW6 Dmel\CG10418 PTHR13829:SF2 SNRNP CORE PROTEIN FAMILY MEMBER U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U6 snRNP#GO:0005688;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0038837|UniProtKB=Q9VDH5 Q9VDH5 KaiR1D PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 DROME|FlyBase=FBgn0033787|UniProtKB=Q7JZZ3 Q7JZZ3 Dmel\CG13321 PTHR31649:SF10 AGAP009604-PA IP19903P-RELATED cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0038236|UniProtKB=Q9VFJ0 Q9VFJ0 Cyp313a1 PTHR24305:SF224 CYTOCHROME P450 CYTOCHROME P450 313A1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0038402|UniProtKB=A0A0B4LH78 A0A0B4LH78 Fer2 PTHR23349:SF97 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0033760|UniProtKB=Q7K2W3 Q7K2W3 Dmel\CG8785 PTHR22950:SF494 AMINO ACID TRANSPORTER GH04538P carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987 intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0026372|UniProtKB=Q9W0A8 Q9W0A8 RpL23A PTHR11620:SF2 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0033058|UniProtKB=Q4V622 Q4V622 CCHa2-R PTHR45695:SF24 LEUCOKININ RECEPTOR-RELATED NEUROPEPTIDE CCHAMIDE-2 RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0029664|UniProtKB=Q9W4R9 Q9W4R9 anon-EST:Posey113 PTHR43462:SF1 ALANYL-TRNA EDITING PROTEIN ALANYL-TRNA EDITING PROTEIN AARSD1 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deacylase activity#GO:0160215;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689 regulation of biological quality#GO:0065008;biological regulation#GO:0065007 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037758|UniProtKB=A0A6H2EG81 A0A6H2EG81 Dmel\CG9467 PTHR15859:SF1 SETA BINDING PROTEIN 1 BTB DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035032|UniProtKB=Q9W141 Q9W141 ATPsynF PTHR13080:SF20 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL-RELATED ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 ATP synthase#PC00002 DROME|FlyBase=FBgn0028513|UniProtKB=Q9VJW8 Q9VJW8 Dmel\CG9254 PTHR11662:SF415 SOLUTE CARRIER FAMILY 17 AT30085P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0037225|UniProtKB=Q9VMZ6 Q9VMZ6 TwdlG PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 DROME|FlyBase=FBgn0037137|UniProtKB=M9PFZ1 M9PFZ1 Nopp140 PTHR23216:SF2 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0040823|UniProtKB=X2J8X8 X2J8X8 dpr6 PTHR23279:SF49 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 10, ISOFORM A-RELATED cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256 DROME|FlyBase=FBgn0039728|UniProtKB=Q9VAD1 Q9VAD1 CT23878 PTHR24366:SF80 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LD30178P immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0037602|UniProtKB=Q9VHP3 Q9VHP3 SLIRP2 PTHR48024:SF70 GEO13361P1-RELATED GEO11133P1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0037541|UniProtKB=A0A0B4KGF6 A0A0B4KGF6 Heatr5 PTHR21663:SF0 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5A DROME|FlyBase=FBgn0005391|UniProtKB=P02844 P02844 Yp2 PTHR11610:SF149 LIPASE FI01450P-RELATED catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0032922|UniProtKB=Q9VIF3 Q9VIF3 Coq3 PTHR43464:SF105 METHYLTRANSFERASE UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220;methyltransferase#PC00155 DROME|FlyBase=FBgn0038450|UniProtKB=Q9VES6 Q9VES6 Dmel\CG17560 PTHR11011:SF60 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038005|UniProtKB=Q9VGB5 Q9VGB5 Cyp313a5 PTHR24305:SF224 CYTOCHROME P450 CYTOCHROME P450 313A1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0261790|UniProtKB=Q9VLV5 Q9VLV5 SmE PTHR11193:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085 intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0000721|UniProtKB=Q03043 Q03043 for PTHR24353:SF111 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;receptor guanylyl cyclase signaling pathway#GO:0007168;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 DROME|FlyBase=FBgn0261996|UniProtKB=F3YD80 F3YD80 CG42814-RA PTHR11839:SF15 UDP/ADP-SUGAR PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196 DROME|FlyBase=FBgn0023177|UniProtKB=O76932 O76932 Pp4-19C PTHR45619:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 DROME|FlyBase=FBgn0036136|UniProtKB=Q9VTF9 Q9VTF9 Ufd1 PTHR12555:SF13 UBIQUITIN FUSION DEGRADATON PROTEIN 1 UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;protein binding#GO:0005515 ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 DROME|FlyBase=FBgn0027335|UniProtKB=Q9VWS3 Q9VWS3 Rip11 PTHR15746:SF23 RAB11-RELATED RAB11 INTERACTING PROTEIN, ISOFORM A small GTPase#PC00208 DROME|FlyBase=FBgn0250843|UniProtKB=P12881 P12881 Prosalpha6 PTHR11599:SF244 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;proteasome complex#GO:0000502 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0050178|UniProtKB=Q8MLQ2 Q8MLQ2 CG17263 PTHR24205:SF16 FOUR AND A HALF LIM DOMAINS PROTEIN GH01042P-RELATED transcription cofactor#PC00217 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 DROME|FlyBase=FBgn0051249|UniProtKB=Q9VEG8 Q9VEG8 CG7477 PTHR15924:SF9 CLE TRNA-SPLICING LIGASE COMPLEX SUBUNIT RTRAF RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0263995|UniProtKB=Q01617 Q01617 cpo PTHR10501:SF49 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B PROTEIN COUCH POTATO RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0038771|UniProtKB=Q7KSB5 Q7KSB5 Dmel\CG4390 PTHR10061:SF0 S-FORMYLGLUTATHIONE HYDROLASE S-FORMYLGLUTATHIONE HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039483|UniProtKB=Q9VB79 Q9VB79 Dmel\CG14259 PTHR11008:SF25 PROTEIN TAKEOUT-LIKE PROTEIN IP09473P-RELATED rhythmic process#GO:0048511;circadian rhythm#GO:0007623 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0036905|UniProtKB=Q9VW36 Q9VW36 Vtld PTHR37962:SF2 MALE STERILE (3) 76CA MALE STERILE (3) 76CA DROME|FlyBase=FBgn0032343|UniProtKB=Q9VKJ8 Q9VKJ8 Idua PTHR12631:SF8 ALPHA-L-IDURONIDASE ALPHA-L-IDURONIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 hydrolase#PC00121;glycosidase#PC00110 DROME|FlyBase=FBgn0063494|UniProtKB=A1ZB71 A1ZB71 GstE6 PTHR43969:SF8 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE E13, ISOFORM A-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 DROME|FlyBase=FBgn0035610|UniProtKB=Q9VRM0 Q9VRM0 Lkr PTHR45695:SF38 LEUCOKININ RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 83 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0288833|UniProtKB=Q9VYW3 Q9VYW3 RPA3 PTHR15114:SF1 REPLICATION PROTEIN A3 REPLICATION PROTEIN A 14 KDA SUBUNIT DNA binding#GO:0003677;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mismatch repair#GO:0006298;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replisome#GO:0030894;replication fork#GO:0005657;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;site of double-strand break#GO:0035861;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 Cell cycle#P00013>Pre-replication Complex#P00478 DROME|FlyBase=FBgn0028699|UniProtKB=A0A6M3Q9I2 A0A6M3Q9I2 Rh50 PTHR11730:SF60 AMMONIUM TRANSPORTER RH50, ISOFORM D channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;transport#GO:0006810;inorganic ion homeostasis#GO:0098771;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0031619|UniProtKB=Q9VR15 Q9VR15 Dmel\CG3355 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0030812|UniProtKB=Q9VX88 Q9VX88 wcy PTHR15911:SF6 WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL binding#GO:0005488;RNA polymerase binding#GO:0070063;chromatin binding#GO:0003682;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of TOR signaling#GO:0032006;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037519|UniProtKB=Q9VHZ9 Q9VHZ9 Dmel\CG3014 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0000303|UniProtKB=P07668 P07668 ChAT PTHR22589:SF14 CARNITINE O-ACYLTRANSFERASE CHOLINE O-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407 signaling#GO:0023052;cell-cell signaling#GO:0007267;biosynthetic process#GO:0009058;biological regulation#GO:0065007;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;cellular process#GO:0009987;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;cell communication#GO:0007154;metabolic process#GO:0008152;neuromuscular synaptic transmission#GO:0007274;trans-synaptic signaling#GO:0099537 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 DROME|FlyBase=FBgn0035649|UniProtKB=Q9VRR2 Q9VRR2 PXo PTHR10783:SF141 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED SOLUTE CARRIER FAMILY 53 MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;efflux transmembrane transporter activity#GO:0015562;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;export from cell#GO:0140352;homeostatic process#GO:0042592;phosphate ion transport#GO:0006817;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0031739|UniProtKB=Q9VMM4 Q9VMM4 Dmel\CG14005 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0028487|UniProtKB=A0A0B4KG03 A0A0B4KG03 f-cup PTHR45752:SF76 LEUCINE-RICH REPEAT-CONTAINING FLYERS-CUP, ISOFORM F regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035978|UniProtKB=Q9VSW1 Q9VSW1 Ugp PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE DROME|FlyBase=FBgn0032202|UniProtKB=Q9VL14 Q9VL14 REPTOR-BP PTHR21051:SF4 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0085424|UniProtKB=P31368 P31368 nub PTHR11636:SF76 POU DOMAIN PROTEIN NUBBIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0030348|UniProtKB=M9PJJ5 M9PJJ5 Dmel\CG10352 PTHR19288:SF4 4-NITROPHENYLPHOSPHATASE-RELATED RE04130P-RELATED catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0030711|UniProtKB=Q9VXL4 Q9VXL4 Rrp47 PTHR15341:SF3 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;DNA binding#GO:0003677 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217 DROME|Gene_ORFName=Dmel_CG33950|UniProtKB=A0ACD4DAU3 A0ACD4DAU3 trol PTHR24270:SF64 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED TERRIBLY REDUCED OPTIC LOBES, ISOFORM BD membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 apolipoprotein#PC00052;transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0031196|UniProtKB=Q9VR64 Q9VR64 Cluap1 PTHR21547:SF0 CLUSTERIN ASSOCIATED PROTEIN 1 CLUSTERIN-ASSOCIATED PROTEIN 1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 DROME|FlyBase=FBgn0003651|UniProtKB=P16376 P16376 svp PTHR24083:SF46 NUCLEAR HORMONE RECEPTOR STEROID RECEPTOR SEVEN-UP, ISOFORM A sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0031908|UniProtKB=Q9VM18 Q9VM18 Tppl PTHR43768:SF3 TREHALOSE 6-PHOSPHATE PHOSPHATASE TREHALOSE 6-PHOSPHATE PHOSPHATASE phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0038331|UniProtKB=Q9VF70 Q9VF70 Ccm3 PTHR13250:SF1 TF-1 CELL APOPTOSIS RELATED PROTEIN-15 PROGRAMMED CELL DEATH PROTEIN 10 protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0036117|UniProtKB=Q9VTD9 Q9VTD9 Dmel\CG6321 PTHR42858:SF1 AMINOTRANSFERASE LD15494P catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 transaminase#PC00216;transferase#PC00220 DROME|FlyBase=FBgn0035630|UniProtKB=Q9VRP2 Q9VRP2 BEST:CK00496 PTHR10804:SF11 PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P PROLIFERATION-ASSOCIATED PROTEIN 2G4 protease#PC00190 DROME|FlyBase=FBgn0038548|UniProtKB=Q9VEF3 Q9VEF3 Dmel\CG17806 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0037502|UniProtKB=Q9VIA6 Q9VIA6 wa-cup PTHR21391:SF0 AT04489P-RELATED AT04489P-RELATED DROME|FlyBase=FBgn0040388|UniProtKB=A8JUV7 A8JUV7 boi PTHR10075:SF131 BASIGIN RELATED INTERFERENCE HEDGEHOG cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0052104|UniProtKB=Q9VTX1 Q9VTX1 anon-69Ag PTHR21483:SF18 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 DROME|FlyBase=FBgn0024227|UniProtKB=Q9VKN7 Q9VKN7 aurB PTHR24350:SF24 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE B catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;microtubule#GO:0005874;spindle microtubule#GO:0005876;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0028370|UniProtKB=Q9V430 Q9V430 kek3 PTHR24366:SF176 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IP22191P immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0264449|UniProtKB=Q9W5D0 Q9W5D0 CG43867 PTHR22903:SF8 PLEKHH PROTEIN PH DOMAIN-CONTAINING PROTEIN Axon guidance mediated by netrin#P00009>MAX-1#P00365 DROME|FlyBase=FBgn0038737|UniProtKB=Q9VDT6 Q9VDT6 Mrm2 PTHR10920:SF18 RIBOSOMAL RNA METHYLTRANSFERASE RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;O-methyltransferase activity#GO:0008171;catalytic activity, acting on a rRNA#GO:0140102 macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;methylation#GO:0032259;rRNA modification#GO:0000154;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0259224|UniProtKB=Q9VZP0 Q9VZP0 CG14972 PTHR28664:SF4 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 cell junction protein#PC00070;tight junction#PC00214 DROME|FlyBase=FBgn0262728|UniProtKB=Q9W1L5 Q9W1L5 Pal2 PTHR10680:SF36 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYL-ALPHA-HYDROXYGLYCINE ALPHA-AMIDATING LYASE 2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 DROME|FlyBase=FBgn0010217|UniProtKB=Q05825 Q05825 ATPsynbeta PTHR15184:SF88 ATP SYNTHASE ATP SYNTHASE F(1) COMPLEX SUBUNIT BETA, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281 proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 ATP synthesis#P02721>F1 beta#P02794 DROME|FlyBase=FBgn0036386|UniProtKB=Q9VUA0 Q9VUA0 CG8833 PTHR13384:SF19 G PATCH DOMAIN-CONTAINING PROTEIN 1 G PATCH DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0052066|UniProtKB=Q7K1H0 Q7K1H0 cyri PTHR12422:SF1 GH09096P GH09096P DROME|FlyBase=FBgn0034255|UniProtKB=A1ZAW9 A1ZAW9 Oxp PTHR22812:SF112 CHROMOBOX PROTEIN CHROMATOR, ISOFORM A-RELATED chromatin binding#GO:0003682;binding#GO:0005488 cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338 chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0260746|UniProtKB=Q9VGE7 Q9VGE7 Ect3 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052 galactosidase#PC00104;hydrolase#PC00121 DROME|FlyBase=FBgn0004360|UniProtKB=P28465 P28465 Wnt2 PTHR12027:SF112 WNT RELATED PROTEIN WNT-2 protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 generation of neurons#GO:0048699;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of JNK cascade#GO:0046328;multicellular organism development#GO:0007275;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;nervous system development#GO:0007399;system development#GO:0048731;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;Wnt signaling pathway#GO:0016055;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 DROME|FlyBase=FBgn0034325|UniProtKB=A1ZB57 A1ZB57 Dmel\CG18539 PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0003002|UniProtKB=P39768 P39768 opa PTHR19818:SF178 ZINC FINGER PROTEIN ZIC AND GLI PAIR-RULE PROTEIN ODD-PAIRED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0029898|UniProtKB=Q9W3W7 Q9W3W7 Dmel\CG14439 PTHR23505:SF96 SPINSTER LP14756P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0033741|UniProtKB=A1Z909 A1Z909 Dmel\CG8545 PTHR22807:SF30 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA base methylation#GO:0070475;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037926|UniProtKB=Q9VGK7 Q9VGK7 Elp1 PTHR12747:SF0 ELONGATOR COMPLEX PROTEIN 1 ELONGATOR COMPLEX PROTEIN 1 tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;elongator holoenzyme complex#GO:0033588;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 general transcription factor#PC00259 PDGF signaling pathway#P00047>Ikk#P01146 DROME|FlyBase=FBgn0002564|UniProtKB=P11997 P11997 Lsp1gamma PTHR11511:SF5 LARVAL STORAGE PROTEIN/PHENOLOXIDASE FAT-BODY PROTEIN 1-RELATED DROME|FlyBase=FBgn0035976|UniProtKB=Q9GNK5 Q9GNK5 PGRP-LC PTHR11022:SF80 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;peptidoglycan muralytic activity#GO:0061783;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0033523|UniProtKB=A1Z897 A1Z897 CG12895 PTHR12469:SF2 PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex II assembly#GO:0034553;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;tricarboxylic acid cycle#GO:0006099;electron transport chain#GO:0022900;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0030552|UniProtKB=Q9VY48 Q9VY48 mRpL38 PTHR11362:SF133 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML38 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 protease inhibitor#PC00191 DROME|FlyBase=FBgn0003523|UniProtKB=Q7KV18 Q7KV18 Ste:CG33242 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;serine/threonine protein kinase complex#GO:1902554;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0032964|UniProtKB=Q9V9Q1 Q9V9Q1 gi7302136 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED DROME|FlyBase=FBgn0287788|UniProtKB=Q4V6M1 Q4V6M1 Datp PTHR21340:SF0 DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside monophosphate metabolic process#GO:0009123;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259 hydrolase#PC00121 DROME|FlyBase=FBgn0037063|UniProtKB=Q7KTW5 Q7KTW5 Dmel\CG9391 PTHR20854:SF4 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;biological regulation#GO:0065007;signaling#GO:0023052;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181 DROME|FlyBase=FBgn0264326|UniProtKB=Q9VCN1 Q9VCN1 PolE1 PTHR10670:SF0 DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740;DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261 transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0035150|UniProtKB=Q9W0P2 Q9W0P2 Rev1 PTHR45990:SF1 DNA REPAIR PROTEIN REV1 TRANSLESION SYNTHESIS PROTEIN REV1 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887 cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0263608|UniProtKB=Q9VV00 Q9VV00 l(3)72Dr PTHR11315:SF0 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE FOLATE GAMMA-GLUTAMYL HYDROLASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0085376|UniProtKB=A8JPC8 A8JPC8 Dmel\CG34347 PTHR23280:SF4 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4A actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0286051|UniProtKB=Q9VRX7 Q9VRX7 Rexo5 PTHR12801:SF82 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 5 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 exoribonuclease#PC00099;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0038053|UniProtKB=Q9VG64 Q9VG64 Dmel\CG18549 PTHR23294:SF0 ET TRANSLATION PRODUCT-RELATED UNC93-LIKE PROTEIN MFSD11 DROME|FlyBase=FBgn0283658|UniProtKB=Q9VM14 Q9VM14 Dlat PTHR23151:SF94 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739 transferase#PC00220;acetyltransferase#PC00038 DROME|FlyBase=FBgn0040350|UniProtKB=Q9V3J5 Q9V3J5 EG:BACR7A4.13 PTHR23511:SF36 SYNAPTIC VESICLE GLYCOPROTEIN 2 EG:BACR7A4.13 PROTEIN-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0035901|UniProtKB=Q9VSK9 Q9VSK9 Pus7 PTHR13326:SF31 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;pseudouridine synthesis#GO:0001522;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0039628|UniProtKB=Q9VAQ4 Q9VAQ4 anon-WO0140519.6 PTHR24260:SF147 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED DROME|FlyBase=FBgn0034908|UniProtKB=Q9W1J3 Q9W1J3 CG5543 PTHR16017:SF0 GASTRULATION DEFECTIVE PROTEIN 1-RELATED WD REPEAT-CONTAINING PROTEIN 70 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0028688|UniProtKB=Q9V3G7 Q9V3G7 Rpn7 PTHR14145:SF1 26S PROTESOME SUBUNIT 6 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0051118|UniProtKB=Q9VC31 Q9VC31 RabX4 PTHR47980:SF29 LD44762P RAS-RELATED PROTEIN RAB-1 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;secretion by cell#GO:0032940;exocytosis#GO:0006887;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0036959|UniProtKB=Q9VWA2 Q9VWA2 CG6951 PTHR11086:SF23 DEOXYCYTIDYLATE DEAMINASE-RELATED DEOXYCYTIDYLATE DEAMINASE catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 deaminase#PC00088;hydrolase#PC00121 DROME|FlyBase=FBgn0027791|UniProtKB=Q9W589 Q9W589 Ofut2 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0029789|UniProtKB=Q9W495 Q9W495 PGAP1 PTHR15495:SF7 NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED GPI INOSITOL-DEACYLASE catalytic activity#GO:0003824;deacylase activity#GO:0160215 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 DROME|FlyBase=FBgn0002926|UniProtKB=P98159 P98159 ndl PTHR24258:SF149 SERINE PROTEASE-RELATED SERINE PROTEASE NDL protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0016694|UniProtKB=Q8SZT1 Q8SZT1 Pdp1 PTHR11988:SF58 THYROTROPH EMBRYONIC FACTOR RELATED GH27708P sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0037688|UniProtKB=Q9VHE3 Q9VHE3 Dmel\CG9356 PTHR13066:SF2 BASIC LEUCINE ZIPPER NUCLEAR FACTOR 1 BLZF1 PROTEIN GOLGIN-45 establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi organization#GO:0007030;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0004959|UniProtKB=Q9VWR5 Q9VWR5 phtm PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 binding#GO:0005488;steroid hydroxylase activity#GO:0008395;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410 membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0031730|UniProtKB=Q9VMN3 Q9VMN3 Cdkl PTHR24056:SF222 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0052407|UniProtKB=Q9VRR3 Q9VRR3 CG10727 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle membrane contact site#GO:0044232 DROME|FlyBase=FBgn0028689|UniProtKB=Q7KLV9 Q7KLV9 Rpn6 PTHR10678:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;proteasome regulatory particle, lid subcomplex#GO:0008541;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 DROME|FlyBase=FBgn0061469|UniProtKB=Q9VTH1 Q9VTH1 Ube3a PTHR45622:SF82 UBIQUITIN-PROTEIN LIGASE E3A-RELATED UBIQUITIN-PROTEIN LIGASE E3A transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of protein catabolic process#GO:0042176;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 DROME|FlyBase=FBgn0038354|UniProtKB=Q9VF45 Q9VF45 Dmel\CG5404 PTHR11814:SF195 SULFATE TRANSPORTER GH25012P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0030234|UniProtKB=Q9VZ71 Q9VZ71 Dmel\CG15211 PTHR22776:SF97 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01453P regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032515|UniProtKB=Q9VJY9 Q9VJY9 loqs PTHR46205:SF3 LOQUACIOUS, ISOFORM B PROTEIN LOQUACIOUS double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;ribonucleoprotein complex#GO:1990904 DROME|FlyBase=FBgn0030435|UniProtKB=Q9VYI1 Q9VYI1 Dmel\CG4645 PTHR12822:SF2 PROTEIN YIPF PROTEIN YIPF endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0036505|UniProtKB=Q95RY2 Q95RY2 CG17014 PTHR12334:SF6 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008 chaperone#PC00072 DROME|FlyBase=FBgn0039212|UniProtKB=Q9VC58 Q9VC58 Syx18 PTHR15959:SF0 SYNTAXIN-18 SYNTAXIN-18 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 SNARE protein#PC00034;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0053263|UniProtKB=Q7KUJ0 Q7KUJ0 CG14106 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0040236|UniProtKB=Q9W350 Q9W350 c11.1 PTHR23120:SF0 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 1 ISOFORM X1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037591|UniProtKB=Q9VHQ6 Q9VHQ6 Or85c PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0050403|UniProtKB=Q8MLV3 Q8MLV3 Dmel\CG30403 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0031574|UniProtKB=Q9VQV6 Q9VQV6 TTLL4B PTHR12241:SF162 TUBULIN POLYGLUTAMYLASE TUBULIN MONOGLUTAMYLASE TTLL4 protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cilium#GO:0005929;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0038797|UniProtKB=Q9VDM3 Q9VDM3 Dic2 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310 phosphate ion transport#GO:0006817;carboxylic acid transmembrane transport#GO:1905039;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744;cellular process#GO:0009987;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0001202|UniProtKB=Q24185 Q24185 hook PTHR18947:SF39 HOOK PROTEINS PROTEIN HOOK protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0034262|UniProtKB=Q8SXT3 Q8SXT3 swi2 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0036128|UniProtKB=A8JNR0 A8JNR0 Elo68beta PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0030992|UniProtKB=M9PI06 M9PI06 CG14192 PTHR10264:SF133 BAND 7 PROTEIN-RELATED AT06885P-RELATED channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;transporter regulator activity#GO:0141108;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0053453|UniProtKB=A1ZBI2 A1ZBI2 Dmel\CG33453 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0039427|UniProtKB=A0A0B4KH14 A0A0B4KH14 Dmel\CG5447 PTHR13254:SF0 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 RAS MODIFICATION PROTEIN ERF4 protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting#GO:0006605 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 DROME|FlyBase=FBgn0052533|UniProtKB=Q9VWI5 Q9VWI5 CG12211 PTHR18934:SF278 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX34-RELATED helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0046886|UniProtKB=Q8IMN6 Q8IMN6 Gr98c PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0033827|UniProtKB=A1Z9B9 A1Z9B9 Dmel\CG17047 PTHR33236:SF12 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0003366|UniProtKB=P13368 P13368 sev PTHR24416:SF527 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0042083|UniProtKB=Q9V9A7 Q9V9A7 Mccc2 PTHR22855:SF13 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;ligase#PC00142 DROME|FlyBase=FBgn0036305|UniProtKB=Q8IQI3 Q8IQI3 Ankrd11 PTHR24149:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0035140|UniProtKB=Q9W0Q3 Q9W0Q3 BORCS6 PTHR13440:SF7 BLOC-1 RELATED COMPLEX SUBUNIT 6 BLOC-1 RELATED COMPLEX SUBUNIT 6 lysosome localization#GO:0032418;organelle localization#GO:0051640;localization#GO:0051179 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0029711|UniProtKB=Q9W4J8 Q9W4J8 Usf PTHR46117:SF3 FI24210P1 FI24210P1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0002579|UniProtKB=P49630 P49630 RpL36 PTHR10114:SF0 60S RIBOSOMAL PROTEIN L36 LARGE RIBOSOMAL SUBUNIT PROTEIN EL36 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0011737|UniProtKB=P54350 P54350 Wee1 PTHR11042:SF185 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0042110|UniProtKB=Q4V4D1 Q4V4D1 Dmel\CG18765 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0033341|UniProtKB=Q7K003 Q7K003 MrgBP PTHR13581:SF5 MRG-BINDING PROTEIN MRG_MORF4L-BINDING PROTEIN regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234 DROME|FlyBase=FBgn0030881|UniProtKB=Q9VX05 Q9VX05 Dmel\CG12985 PTHR37161:SF2 HDC10475 AT11648P-RELATED DROME|FlyBase=FBgn0036882|UniProtKB=Q7JQV2 Q7JQV2 Dred PTHR18916:SF95 DYNACTIN 1-RELATED MICROTUBULE-BINDING DYNACTIN SUBUNIT 1 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;mitotic cell cycle process#GO:1903047;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;spindle localization#GO:0051653;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010;nuclear migration#GO:0007097;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278 neuron projection#GO:0043005;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;spindle#GO:0005819;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;axon#GO:0030424;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 chaperone#PC00072 Huntington disease#P00029>Dynactin#P00781 DROME|FlyBase=FBgn0005558|UniProtKB=O18381 O18381 ey PTHR45636:SF58 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0011274|UniProtKB=P98149 P98149 Dif PTHR24169:SF28 NUCLEAR FACTOR NF-KAPPA-B PROTEIN DORSAL-RELATED IMMUNITY FACTOR DIF-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of DNA-templated transcription#GO:0045893;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;DNA-binding transcription factor#PC00218 Toll pathway-drosophila#P06217>DL#P06344;Toll receptor signaling pathway#P00054>NFkappaB#P01354 DROME|FlyBase=FBgn0034968|UniProtKB=Q9W1B9 Q9W1B9 RpL12 PTHR11661:SF2 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11 binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 DROME|FlyBase=FBgn0039476|UniProtKB=Q9VB88 Q9VB88 DmelL1 PTHR11610:SF178 LIPASE FI01825P-RELATED catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0039319|UniProtKB=Q9VBS9 Q9VBS9 Dmel\CG13659 PTHR11012:SF12 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0085300|UniProtKB=A8JNL8 A8JNL8 Cpr65Ay PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0035385|UniProtKB=Q9VZW5 Q9VZW5 FMRFaR PTHR46641:SF26 FMRFAMIDE RECEPTOR-RELATED FMRFAMIDE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0040345|UniProtKB=Q7KW25 Q7KW25 Dmel\CG3708 PTHR11875:SF7 TESTIS-SPECIFIC Y-ENCODED PROTEIN AT14585P-RELATED binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|Gene_ORFName=Dmel_CG30048|UniProtKB=A0ACD4DAI6 A0ACD4DAI6 CG30048 PTHR46730:SF1 POLYCYSTIN-1 POLYCYSTIN-1-LIKE PROTEIN 1 ISOFORM X1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0263606|UniProtKB=A8JNT7 A8JNT7 Hsc20 PTHR14021:SF20 IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 DROME|FlyBase=FBgn0045498|UniProtKB=P84181 P84181 Gr22d PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037007|UniProtKB=Q9VPD6 Q9VPD6 BNIP3 PTHR15186:SF5 RE48077P BNIP3, ISOFORM A positive regulation of apoptotic process#GO:0043065;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;macroautophagy#GO:0016236;apoptotic mitochondrial changes#GO:0008637;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;nucleus#GO:0005634 DROME|FlyBase=FBgn0035722|UniProtKB=Q9VRZ7 Q9VRZ7 Uqcc1 PTHR12184:SF1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0027052|UniProtKB=Q9XYW6 Q9XYW6 STUB1 PTHR46803:SF5 E3 UBIQUITIN-PROTEIN LIGASE CHIP E3 UBIQUITIN-PROTEIN LIGASE CHIP protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein-folding chaperone binding#GO:0051087 positive regulation of metabolic process#GO:0009893;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;response to misfolded protein#GO:0051788;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to topologically incorrect protein#GO:0035967;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular response to misfolded protein#GO:0071218;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522 I band#GO:0031674;intracellular organelle#GO:0043229;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>CHIP#P01214 DROME|FlyBase=FBgn0034071|UniProtKB=Q7K4L9 Q7K4L9 R5_2R:11947059..11948303 PTHR21650:SF4 MEMBRALIN/KINETOCHORE PROTEIN NUF2 MEMBRALIN biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of ERAD pathway#GO:1904292;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;cellular response to stimulus#GO:0051716;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of cellular response to stress#GO:0080135;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;response to endoplasmic reticulum stress#GO:0034976 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0020248|UniProtKB=Q9W0E9 Q9W0E9 stet PTHR45840:SF2 RHOMBOID-RELATED PROTEIN PROTEIN RHOMBOID-RELATED DROME|FlyBase=FBgn0038167|UniProtKB=Q8T9L5 Q8T9L5 Lkb1 PTHR24346:SF94 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE STK11 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>LKB1#P04647 DROME|FlyBase=FBgn0035407|UniProtKB=Q9VZU1 Q9VZU1 Asciz PTHR46664:SF1 ATM INTERACTOR ATM INTERACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0034136|UniProtKB=Q7K4Y6 Q7K4Y6 DAT PTHR11616:SF341 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT DOPAMINE TRANSPORTER active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;neurotransmitter transport#GO:0006836;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;nitrogen compound transport#GO:0071705;synaptic signaling#GO:0099536;sodium ion transmembrane transport#GO:0035725;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic transmission, dopaminergic#GO:0001963;establishment of localization#GO:0051234;import into cell#GO:0098657;amino acid transport#GO:0006865;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular localization#GO:0051641;organic hydroxy compound transport#GO:0015850;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell body#GO:0044297;axon#GO:0030424;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 primary active transporter#PC00068 DROME|FlyBase=FBgn0261244|UniProtKB=B7Z150 B7Z150 inaE PTHR45792:SF14 DIACYLGLYCEROL LIPASE HOMOLOG-RELATED DIACYLGLYCEROL LIPASE-ALPHA hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;triacylglycerol lipase activity#GO:0004806;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 system development#GO:0048731;anatomical structure development#GO:0048856;catabolic process#GO:0009056;primary metabolic process#GO:0044238;neurogenesis#GO:0022008;neutral lipid metabolic process#GO:0006638;cellular developmental process#GO:0048869;developmental process#GO:0032502;neutral lipid catabolic process#GO:0046461;lipid metabolic process#GO:0006629;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;multicellular organismal process#GO:0032501;oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;olefinic compound metabolic process#GO:0120254;glycerolipid catabolic process#GO:0046503;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;acylglycerol catabolic process#GO:0046464;multicellular organism development#GO:0007275;unsaturated fatty acid metabolic process#GO:0033559;metabolic process#GO:0008152;nervous system development#GO:0007399;icosanoid metabolic process#GO:0006690;lipid catabolic process#GO:0016042;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron projection membrane#GO:0032589 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0050108|UniProtKB=A1ZAX2 A1ZAX2 Triap1 PTHR46403:SF2 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 AT19138P-RELATED localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;lipid localization#GO:0010876;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;phospholipid transport#GO:0015914;membrane organization#GO:0061024;intermembrane phospholipid transfer#GO:0120010;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0260799|UniProtKB=Q7PLI0 Q7PLI0 p120ctn PTHR10372:SF27 PLAKOPHILLIN-RELATED P120 CATENIN cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 intermediate filament binding protein#PC00130;cytoskeletal protein#PC00085;intermediate filament#PC00129 DROME|FlyBase=FBgn0290324|UniProtKB=Q9W1I8 Q9W1I8 Snap29 PTHR19305:SF42 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 29 protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149 secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 membrane traffic protein#PC00150;SNARE protein#PC00034 5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049 DROME|FlyBase=FBgn0267429|UniProtKB=A0A0S0WGX2 A0A0S0WGX2 lovit PTHR19432:SF35 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0025383|UniProtKB=Q9W586 Q9W586 Dmel\CG14780 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0037046|UniProtKB=Q9VP84 Q9VP84 Dmel\CG10581 PTHR43146:SF1 CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0036335|UniProtKB=Q9VU36 Q9VU36 mRpL20 PTHR10986:SF16 39S RIBOSOMAL PROTEIN L20 LARGE RIBOSOMAL SUBUNIT PROTEIN BL20M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 ribosomal protein#PC00202 DROME|FlyBase=FBgn0037275|UniProtKB=Q9VN56 Q9VN56 Dmel\CG14655 PTHR24390:SF291 ZINC FINGER PROTEIN GH23506P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0035453|UniProtKB=Q9VZN6 Q9VZN6 Dmel\CG10357 PTHR11610:SF202 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0039886|UniProtKB=Q9V9S4 Q9V9S4 Dmel\CG2003 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0051702|UniProtKB=Q8IME8 Q8IME8 tplus3a PTHR13115:SF8 RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591 DROME|FlyBase=FBgn0052110|UniProtKB=Q8IQH8 Q8IQH8 Dmel\CG32110 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protease#PC00190 DROME|FlyBase=FBgn0039083|UniProtKB=Q9VCL7 Q9VCL7 Dmel\CG10177 PTHR44167:SF34 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED DOUBLECORTIN-LIKE AND CAM KINASE-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032704|UniProtKB=Q9VJ59 Q9VJ59 Jwa PTHR12859:SF0 PRA1 PROTEIN PRA1 FAMILY PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 DROME|FlyBase=FBgn0052679|UniProtKB=Q8IRL3 Q8IRL3 Dmel\CG32679 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0015576|UniProtKB=Q9VIB3 Q9VIB3 alpha-Est8 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0035187|UniProtKB=Q9W0K2 Q9W0K2 Trhn PTHR11473:SF43 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 2 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 metabolic process#GO:0008152;serotonin metabolic process#GO:0042428;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;phenol-containing compound metabolic process#GO:0018958;phenol-containing compound biosynthetic process#GO:0046189;biosynthetic process#GO:0009058;serotonin biosynthetic process#GO:0042427 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 DROME|FlyBase=FBgn0033402|UniProtKB=Q7K105 Q7K105 Myd88 PTHR15079:SF3 MYD88 MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;defense response to Gram-positive bacterium#GO:0050830;regulation of biological process#GO:0050789;defense response to bacterium#GO:0042742;immune system process#GO:0002376;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;response to other organism#GO:0051707;toll-like receptor 4 signaling pathway#GO:0034142;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;activation of innate immune response#GO:0002218;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>MyD88#P01377;Toll pathway-drosophila#P06217>MyD88#P06346 DROME|FlyBase=FBgn0029512|UniProtKB=Q7KSM5 Q7KSM5 Aos1 PTHR10953:SF162 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 1 ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 DROME|FlyBase=FBgn0000319|UniProtKB=P29742 P29742 Chc PTHR10292:SF46 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cell cortex#GO:0005938;vesicle#GO:0031982;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle#GO:0030136 vesicle coat protein#PC00235;membrane traffic protein#PC00150 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 DROME|FlyBase=FBgn0030997|UniProtKB=Q9VWK6 Q9VWK6 CG7990 PTHR12892:SF17 FGF RECEPTOR ACTIVATING PROTEIN 1 POST-GPI ATTACHMENT TO PROTEINS FACTOR 2-LIKE biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032052|UniProtKB=Q9VLK0 Q9VLK0 PIG-U PTHR13121:SF0 GPI TRANSAMIDASE COMPONENT PIG-U GPI-ANCHOR TRANSAMIDASE COMPONENT PIGU metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchored protein biosynthesis#GO:0180046 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;caspase complex#GO:0008303;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827 DROME|FlyBase=FBgn0085487|UniProtKB=A8DYG0 A8DYG0 SP118 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0010825|UniProtKB=M9PHT1 M9PHT1 Gug PTHR13859:SF11 ATROPHIN-RELATED GRUNGE, ISOFORM J transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0035047|UniProtKB=Q9W123 Q9W123 Pof PTHR23003:SF71 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN FI21236P1-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;nuclear mRNA surveillance#GO:0071028;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;rRNA processing#GO:0006364 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0033088|UniProtKB=Q7K0P4 Q7K0P4 PGAP3 PTHR13148:SF0 PER1-RELATED GPI-SPECIFIC PHOSPHOLIPASE A2-LIKE PGAP3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0033240|UniProtKB=A8DY65 A8DY65 Dmel\CG2906 PTHR12496:SF2 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25B RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0031109|UniProtKB=Q9VR94 Q9VR94 Obp19a PTHR21364:SF2 GENERAL ODORANT-BINDING PROTEIN 19A GENERAL ODORANT-BINDING PROTEIN 19A DROME|FlyBase=FBgn0085410|UniProtKB=Q9VML9 Q9VML9 TrissinR PTHR24241:SF194 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRISSIN RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0287864|UniProtKB=A1Z9X4 A1Z9X4 hbs PTHR11640:SF136 NEPHRIN NEPHRIN cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0034205|UniProtKB=A1ZAR6 A1ZAR6 Dmel\CG10950 PTHR12363:SF42 TRANSPORTIN 3 AND IMPORTIN 13 TRANSPORTIN-3 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0028567|UniProtKB=Q9W0F0 Q9W0F0 robl62A PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dynein complex#GO:0030286;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037877|UniProtKB=Q9VGR8 Q9VGR8 Dmel\CG6689 PTHR24376:SF216 ZINC FINGER PROTEIN DRACULIN-LIKE 3 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0259175|UniProtKB=A2RVG6 A2RVG6 ome PTHR11731:SF192 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED VENOM DIPEPTIDYL PEPTIDASE 4 peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0038381|UniProtKB=Q9VF14 Q9VF14 EndoU PTHR12439:SF42 PLACENTAL PROTEIN 11-RELATED ENDORIBONUCLEASE ARLR-RELATED nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 post-transcriptional gene silencing#GO:0016441;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0015320|UniProtKB=P52485 P52485 Ubc2 PTHR24068:SF41 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2-24 KDA transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0039111|UniProtKB=Q86BN8 Q86BN8 PTPMT1 PTHR46712:SF1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 DROME|FlyBase=FBgn0031484|UniProtKB=Q9VQJ7 Q9VQJ7 Dmel\CG3165 PTHR13058:SF19 THREE PRIME REPAIR EXONUCLEASE 1, 2 LD40940P 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527 cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0260479|UniProtKB=Q95TF4 Q95TF4 CG13796 PTHR11616:SF337 SODIUM/CHLORIDE DEPENDENT TRANSPORTER BLOATED TUBULES, ISOFORM B-RELATED glycine transmembrane transporter activity#GO:0015187;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943 nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;glycine transport#GO:0015816;monoatomic cation transport#GO:0006812;localization#GO:0051179;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 DROME|FlyBase=FBgn0036040|UniProtKB=Q9VT44 Q9VT44 Dmel\CG6749 PTHR45617:SF169 LEUCINE RICH REPEAT FAMILY PROTEIN LP04042P scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0260486|UniProtKB=M9PCG3 M9PCG3 Ziz PTHR23317:SF26 DEDICATOR OF CYTOKINESIS DOCK ZIZIMIN, ISOFORM K guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0052523|UniProtKB=Q8IQ51 Q8IQ51 Dmel\CG32523 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0259167|UniProtKB=Q8IQ55 Q8IQ55 CG32415 PTHR46780:SF25 PROTEIN EVA-1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 62 DROME|FlyBase=FBgn0052320|UniProtKB=Q8IRH3 Q8IRH3 Dmel\CG32320 PTHR21041:SF9 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN-LIKE DOMAIN-CONTAINING PROTEIN single fertilization#GO:0007338;sexual reproduction#GO:0019953;fertilization#GO:0009566;reproductive process#GO:0022414 DROME|FlyBase=FBgn0030440|UniProtKB=Q9VYH6 Q9VYH6 Dmel\CG15719 PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0033799|UniProtKB=A1Z991 A1Z991 GLaz PTHR10612:SF41 APOLIPOPROTEIN D GLIAL LAZARILLO, ISOFORM A cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;response to chemical#GO:0042221;response to stimulus#GO:0050896;lipid metabolic process#GO:0006629;response to oxygen-containing compound#GO:1901700;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 apolipoprotein#PC00052 DROME|FlyBase=FBgn0034567|UniProtKB=Q9W2P2 Q9W2P2 Dmel\CG15651 PTHR13627:SF31 FUKUTIN RELATED PROTEIN RIBITOL 5-PHOSPHATE TRANSFERASE FKRP transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 DROME|FlyBase=FBgn0038606|UniProtKB=A0A0B4LIC4 A0A0B4LIC4 Dmel\CG15803 PTHR19964:SF20 MULTIPLE PDZ DOMAIN PROTEIN PATJ HOMOLOG-LIKE PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033490|UniProtKB=Q4V3G1 Q4V3G1 Dmel\CG12917 PTHR13966:SF19 ENDONUCLEASE RELATED DNA_RNA NON-SPECIFIC ENDONUCLEASE DOMAIN-CONTAINING PROTEIN-RELATED nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on DNA#GO:0140097 cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 DROME|FlyBase=FBgn0032873|UniProtKB=Q9VIK9 Q9VIK9 CG2614 PTHR12176:SF78 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 DROME|FlyBase=FBgn0058191|UniProtKB=Q7PLT1 Q7PLT1 Dmel\CG40191 PTHR15615:SF127 FAMILY NOT NAMED PROTEIN CNPPD1 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 DROME|FlyBase=FBgn0035755|UniProtKB=Q9VS39 Q9VS39 Dmel\CG14830 PTHR41155:SF1 FI19525P1 FI19525P1 DROME|FlyBase=FBgn0025837|UniProtKB=M9NFP5 M9NFP5 Dmel\CG17636 PTHR11686:SF9 GAMMA GLUTAMYL TRANSPEPTIDASE GAMMA-GLUTAMYL TRANSPEPTIDASE, ISOFORM A catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0020414|UniProtKB=Q8MLZ7 Q8MLZ7 Idgf3 PTHR11177:SF235 CHITINASE CHITINASE-LIKE PROTEIN IDGF1-RELATED chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0038826|UniProtKB=A0A0B4KHI4 A0A0B4KHI4 Syp PTHR21245:SF10 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN PROTEIN TUMOROUS TESTIS-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034184|UniProtKB=A1ZAP1 A1ZAP1 Dmel\CG9646 PTHR21477:SF13 ZGC:172139 KIAA0930 DROME|FlyBase=FBgn0034368|UniProtKB=Q7K3D4 Q7K3D4 zda PTHR46512:SF1 PEPTIDYLPROLYL ISOMERASE PEPTIDYLPROLYL ISOMERASE metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;cytosol#GO:0005829;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0261270|UniProtKB=O18373 O18373 Sps1 PTHR10256:SF0 SELENIDE, WATER DIKINASE INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0029995|UniProtKB=Q9W3K8 Q9W3K8 Dmel\CG2256 PTHR23055:SF60 CALCIUM BINDING PROTEINS CALAXIN binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 DROME|FlyBase=FBgn0033809|UniProtKB=A0A0B4KFK6 A0A0B4KFK6 Dmel\CG4630 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0032264|UniProtKB=M9PCU5 M9PCU5 Lip4 PTHR11005:SF144 LYSOSOMAL ACID LIPASE-RELATED AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0050499|UniProtKB=Q95RV5 Q95RV5 Rpe PTHR11749:SF3 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;D-ribulose-phosphate 3-epimerase activity#GO:0004750;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;nucleotide metabolic process#GO:0009117;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 DROME|FlyBase=FBgn0039941|UniProtKB=Q7PLW4 Q7PLW4 CG40146 PTHR10846:SF2 SODIUM/POTASSIUM/CALCIUM EXCHANGER RE48874P passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0027660|UniProtKB=Q8IQQ7 Q8IQQ7 blot PTHR11616:SF337 SODIUM/CHLORIDE DEPENDENT TRANSPORTER BLOATED TUBULES, ISOFORM B-RELATED amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;glycine transmembrane transporter activity#GO:0015187;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171 sodium ion transport#GO:0006814;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;establishment of localization#GO:0051234;import into cell#GO:0098657 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 DROME|FlyBase=FBgn0261444|UniProtKB=Q9W5A5 Q9W5A5 Motor PTHR12424:SF18 TWEETY-RELATED PROTEIN MOVEMENT MODULATOR monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0033469|UniProtKB=A1Z824 A1Z824 SP15 PTHR24260:SF144 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED Toll pathway-drosophila#P06217>SPE#P06340 DROME|FlyBase=FBgn0004573|UniProtKB=P20905 P20905 5-HT7 PTHR24247:SF202 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 DROME|FlyBase=FBgn0038082|UniProtKB=Q9VG30 Q9VG30 Ugt37A2 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 DROME|FlyBase=FBgn0002031|UniProtKB=P24156 P24156 Phb1 PTHR23222:SF0 PROHIBITIN PROHIBITIN 1 DROME|FlyBase=FBgn0034405|UniProtKB=Q7KB18 Q7KB18 Jheh2 PTHR21661:SF35 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803 metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 DROME|FlyBase=FBgn0034975|UniProtKB=Q9W1A9 Q9W1A9 enok PTHR10615:SF217 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;histone acetyltransferase activity#GO:0004402;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;binding#GO:0005488;transcription regulator activity#GO:0140110;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0023522|UniProtKB=Q9I7X6 Q9I7X6 unmet PTHR12303:SF14 CARNOSINE N-METHYLTRANSFERASE PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE CARNMT1 transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0039577|UniProtKB=Q9VAW6 Q9VAW6 Dmel\CG12516 PTHR21644:SF0 AT02555P-RELATED AT02555P-RELATED DROME|FlyBase=FBgn0020272|UniProtKB=O01939 O01939 mst PTHR13391:SF1 MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO PROTEIN MISATO HOMOLOG 1 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0023528|UniProtKB=Q29R09 Q29R09 Dmel\CG2924 PTHR24068:SF33 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0039210|UniProtKB=Q9VC60 Q9VC60 anon-WO0118547.376 PTHR31809:SF0 BUD13 HOMOLOG BUD13 HOMOLOG nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0027657|UniProtKB=Q9VF15 Q9VF15 glob1 PTHR46458:SF1 BLR2807 PROTEIN NEUROGLOBIN molecular carrier activity#GO:0140104;small molecule binding#GO:0036094;binding#GO:0005488 transport#GO:0006810;response to hypoxia#GO:0001666;establishment of localization#GO:0051234;localization#GO:0051179;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;response to stimulus#GO:0050896 transporter#PC00227 DROME|FlyBase=FBgn0030088|UniProtKB=Q9W389 Q9W389 Arfrp1 PTHR45909:SF1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to cell periphery#GO:1990778;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane transport#GO:0006893;protein localization to organelle#GO:0033365;Golgi to plasma membrane protein transport#GO:0043001;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0052183|UniProtKB=Q9VVK3 Q9VVK3 Ccn PTHR11348:SF17 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN glycosaminoglycan binding#GO:0005539;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;integrin binding#GO:0005178 regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0029838|UniProtKB=Q9W440 Q9W440 CG4666 PTHR12475:SF14 FAMILY NOT NAMED PROTEIN THEM6 DROME|FlyBase=FBgn0010314|UniProtKB=Q24152 Q24152 Cks30A PTHR23415:SF29 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT-RELATED kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase activator activity#GO:0030295;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 mitotic cell cycle process#GO:1903047;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle phase transition#GO:0044772;cell cycle#GO:0007049 protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0053057|UniProtKB=Q86BH3 Q86BH3 Tpt PTHR12684:SF2 PUTATIVE PHOSPHOTRANSFERASE TRNA 2'-PHOSPHOTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0261556|UniProtKB=Q9VW85 Q9VW85 CG13812 PTHR13217:SF11 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 5 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 endothelial cell migration#GO:0043542;cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987 intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 DROME|FlyBase=FBgn0010421|UniProtKB=P41900 P41900 TfIIFbeta PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 DROME|FlyBase=FBgn0053237|UniProtKB=Q7KV13 Q7KV13 Ste:CG33237 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0003480|UniProtKB=O77135 O77135 spn-B PTHR46487:SF1 DNA REPAIR PROTEIN XRCC3 DNA REPAIR PROTEIN XRCC3 nucleic acid binding#GO:0003676;binding#GO:0005488;four-way junction DNA binding#GO:0000400;DNA binding#GO:0003677 DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;cellular response to stress#GO:0033554;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;telomere organization#GO:0032200;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;replication fork#GO:0005657;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0036036|UniProtKB=Q9VT39 Q9VT39 Dmel\CG14174 PTHR34761:SF1 NUCLEOLUS AND NEURAL PROGENITOR PROTEIN RIBONUCLEASE MRP SUBUNIT P64 positive regulation of signal transduction#GO:0009967;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of response to stimulus#GO:0048584;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0261053|UniProtKB=Q9VGW1 Q9VGW1 Cad86C PTHR24026:SF96 FAT ATYPICAL CADHERIN-RELATED CADHERIN-86C cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell-cell junction#GO:0005911 cadherin#PC00057 DROME|FlyBase=FBgn0039920|UniProtKB=Q9V4F3 Q9V4F3 Dmel\CG11360 PTHR23285:SF7 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 LD09246P1 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0025642|UniProtKB=O77424 O77424 EG:114D9.1 PTHR46002:SF5 EG:114D9.1 PROTEIN-RELATED EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0004595|UniProtKB=P29617 P29617 pros PTHR12198:SF0 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 HOMEOBOX PROTEIN PROSPERO sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0052441|UniProtKB=Q8IPT0 Q8IPT0 EMC10 PTHR21397:SF6 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0013272|UniProtKB=Q8MLT4 Q8MLT4 Gp150 PTHR45617:SF171 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0005322|UniProtKB=Q9VL02 Q9VL02 nmd PTHR45644:SF88 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED FI08533P-RELATED localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 DROME|FlyBase=FBgn0032512|UniProtKB=Q9VJZ3 Q9VJZ3 Bdp1 PTHR22929:SF0 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032363|UniProtKB=Q9VKG8 Q9VKG8 Dlg5 PTHR46360:SF1 DISKS LARGE HOMOLOG 5 DISKS LARGE HOMOLOG 5 negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039626|UniProtKB=Q9VAQ7 Q9VAQ7 Slu7 PTHR12942:SF2 STEP II SPLICING FACTOR SLU7 PRE-MRNA-SPLICING FACTOR SLU7 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;pre-mRNA binding#GO:0036002 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0261624|UniProtKB=Q9VRC5 Q9VRC5 I-3 PTHR20835:SF0 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase binding#GO:0019903 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0250819|UniProtKB=Q59DP4 Q59DP4 anon-EST:fe2A9 PTHR24215:SF37 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE-RICH PROTEIN 1 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0038188|UniProtKB=Q9VFP9 Q9VFP9 Art9 PTHR11006:SF124 PROTEIN ARGININE N-METHYLTRANSFERASE ARGININE METHYLTRANSFERASE 9-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031903|UniProtKB=Q9VM25 Q9VM25 Wnt10 PTHR12027:SF98 WNT RELATED PROTEIN WNT signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 system development#GO:0048731;cell fate commitment#GO:0045165;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0052238|UniProtKB=Q9VZ97 Q9VZ97 TTLL1B PTHR12241:SF31 TUBULIN POLYGLUTAMYLASE POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1 catalytic activity, acting on a protein#GO:0140096;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281 intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0035379|UniProtKB=Q9VZX1 Q9VZX1 spz5 PTHR23199:SF18 NEUROTROPHIN 1-RELATED PROTEIN SPAETZLE-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;response to external stimulus#GO:0009605;innate immune response#GO:0045087;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;response to other organism#GO:0051707;multicellular organismal process#GO:0032501;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;central nervous system development#GO:0007417;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Toll pathway-drosophila#P06217>SPZ#P06349;Toll pathway-drosophila#P06217>SPZ full length#P06347 DROME|FlyBase=FBgn0015794|UniProtKB=Q9W4A0 Q9W4A0 Rab18 PTHR24073:SF1242 DRAB5-RELATED RAS-RELATED PROTEIN RAB-18 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;lipid droplet organization#GO:0034389;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 DROME|FlyBase=FBgn0034976|UniProtKB=Q9W1A8 Q9W1A8 Arip4 PTHR45797:SF1 RAD54-LIKE HELICASE ARIP4 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0035036|UniProtKB=Q9W137 Q9W137 Cg4707 PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0025643|UniProtKB=Q9W4V1 Q9W4V1 EG:100G7.6 PTHR23213:SF368 FORMIN-RELATED HISTONE H3-K79 METHYLTRANSFERASE actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029 organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0284435|UniProtKB=Q8MS37 Q8MS37 tyn PTHR47327:SF24 FI18240P1-RELATED RE15579P anatomical structure development#GO:0048856;developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653 DROME|FlyBase=FBgn0052438|UniProtKB=Q8IPT2 Q8IPT2 SMC5 PTHR45916:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697 cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 condensed chromosome#GO:0000793;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0036362|UniProtKB=Q8IQJ4 Q8IQJ4 Dmel\CG10725 PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;carbohydrate derivative binding#GO:0097367 external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0000047|UniProtKB=P83967 P83967 Act88F PTHR11937:SF387 ACTIN ACTIN, INDIRECT FLIGHT MUSCLE-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 DROME|FlyBase=FBgn0260655|UniProtKB=Q9VW22 Q9VW22 l(3)76BDm PTHR12975:SF6 TRANSPORT PROTEIN TRAPP TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;TRAPP complex#GO:0030008 DROME|FlyBase=FBgn0004606|UniProtKB=P28166 P28166 zfh1 PTHR24391:SF27 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0040261|UniProtKB=Q9VJH9 Q9VJH9 Ugt37E1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740 DROME|FlyBase=FBgn0032235|UniProtKB=Q9VKX6 Q9VKX6 CT16355 PTHR45617:SF4 LEUCINE RICH REPEAT FAMILY PROTEIN TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC32 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032194|UniProtKB=Q9VL25 Q9VL25 ath PTHR18934:SF118 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX33 ATP-dependent activity#GO:0140657;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;helicase activity#GO:0004386 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase I#GO:0045943;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase I#GO:0006356 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039135|UniProtKB=Q9VCF1 Q9VCF1 Dmel\CG13603 PTHR31872:SF4 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179 DROME|FlyBase=FBgn0052054|UniProtKB=Q8IQE0 Q8IQE0 Dmel\CG32054 PTHR23529:SF2 GH19118P-RELATED GH19118P-RELATED DROME|FlyBase=FBgn0004379|UniProtKB=Q9VSW5 Q9VSW5 Klp67A PTHR24115:SF372 KINESIN-RELATED KINESIN-LIKE PROTEIN plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;mitotic sister chromatid segregation#GO:0000070;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule depolymerization#GO:0007019;chromosome localization#GO:0050000;protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle fission#GO:0048285;cellular component disassembly#GO:0022411;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;protein-containing complex disassembly#GO:0032984 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic microtubule#GO:0005881;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;spindle microtubule#GO:0005876;microtubule#GO:0005874 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0259986|UniProtKB=Q59E55 Q59E55 nab PTHR12623:SF10 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN HOMOLOG transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0086904|UniProtKB=Q94518 Q94518 Nacalpha PTHR21713:SF4 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED GH09281P-RELATED protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0034139|UniProtKB=Q4V3U8 Q4V3U8 SP42 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0035392|UniProtKB=Q9VZV9 Q9VZV9 Dmel\CG1271 PTHR10196:SF68 SUGAR KINASE GLYCEROL KINASE 5 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;carbohydrate metabolic process#GO:0005975;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;carbohydrate derivative biosynthetic process#GO:1901137;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 carbohydrate kinase#PC00065;kinase#PC00137 DROME|FlyBase=FBgn0028935|UniProtKB=Q9VJN2 Q9VJN2 BG:DS00365.1 PTHR11533:SF253 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0039682|UniProtKB=Q9VAI9 Q9VAI9 Obp99c PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0259216|UniProtKB=H9XVN1 H9XVN1 RhoGAP102A PTHR12635:SF7 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE ACTIVATING PROTEIN 36-RELATED enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 DROME|FlyBase=FBgn0010741|UniProtKB=Q9VTE5 Q9VTE5 Pfdn2 PTHR13303:SF0 PREFOLDIN SUBUNIT 2 PREFOLDIN SUBUNIT 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991 chaperone#PC00072 DROME|FlyBase=FBgn0011640|UniProtKB=Q94901 Q94901 lark PTHR23147:SF291 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN LARK cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0265194|UniProtKB=A8DYE2 A8DYE2 Trpm PTHR13800:SF1 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL TRPM channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0032754|UniProtKB=Q9VJ03 Q9VJ03 Dmel\CG10700 PTHR43557:SF2 APOPTOSIS-INDUCING FACTOR 1 RIESKE DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176 DROME|FlyBase=FBgn0035603|UniProtKB=Q9VRL3 Q9VRL3 Pfdn4 PTHR21100:SF9 PREFOLDIN SUBUNIT 4 PREFOLDIN SUBUNIT 4 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0001565|UniProtKB=Q9VRI0 Q9VRI0 Ddx56 PTHR24031:SF781 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX56-RELATED rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;response to external stimulus#GO:0009605;defense response#GO:0006952;macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;response to other organism#GO:0051707;response to virus#GO:0009615;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to external biotic stimulus#GO:0043207;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;response to biotic stimulus#GO:0009607;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;defense response to virus#GO:0051607;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0033324|UniProtKB=A1Z7I1 A1Z7I1 Dmel\CG14744 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0261067|UniProtKB=Q9W2K2 Q9W2K2 LSm1 PTHR15588:SF8 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of RNA stability#GO:0043487;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0034145|UniProtKB=A1ZAI5 A1ZAI5 CG5065 PTHR11011:SF130 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034921|UniProtKB=Q9W1H5 Q9W1H5 DCP1 PTHR16290:SF0 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 DECAPPING PROTEIN 1, ISOFORM A RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;RNA catabolic process#GO:0006401;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 mRNA capping factor#PC00145;RNA processing factor#PC00147 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 DROME|FlyBase=FBgn0035879|UniProtKB=A8JNN5 A8JNN5 GAPcenA PTHR47219:SF9 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;molecular function activator activity#GO:0140677 G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0031736|UniProtKB=Q9VMM7 Q9VMM7 Dmel\CG11030 PTHR13237:SF9 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED NEUROGUIDIN maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030410|UniProtKB=Q9VYK8 Q9VYK8 Aven PTHR16524:SF2 CELL DEATH REGULATOR AVEN CELL DEATH REGULATOR AVEN regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;negative regulation of mitotic cell cycle#GO:0045930 DROME|FlyBase=FBgn0030590|UniProtKB=Q9VY08 Q9VY08 Dm GMCzeta1 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0032303|UniProtKB=Q9VKP7 Q9VKP7 Dmel\CG6508 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219;programmed cell death#GO:0012501;primary metabolic process#GO:0044238 aspartic protease#PC00053;protease#PC00190 DROME|FlyBase=FBgn0002552|UniProtKB=Q9V4Z9 Q9V4Z9 lin PTHR16057:SF1 WINS1, 2 PROTEIN PROTEIN LINES HOMOLOG 1 DROME|FlyBase=FBgn0031707|UniProtKB=M9PB43 M9PB43 Dmel\CG14020 PTHR14605:SF1 CHST5 PROTEIN TRANSMEMBRANE PROTEIN 231 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;regulation of protein localization#GO:0032880;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;cell projection organization#GO:0030030 cell projection membrane#GO:0031253;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;organelle#GO:0043226;ciliary membrane#GO:0060170;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0067864|UniProtKB=Q9NB04 Q9NB04 Patj PTHR19964:SF92 MULTIPLE PDZ DOMAIN PROTEIN PATJ HOMOLOG scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051380|UniProtKB=Q8IMS4 Q8IMS4 Dmel\CG31380 PTHR11012:SF13 PROTEIN KINASE-LIKE DOMAIN-CONTAINING AT27361P-RELATED DROME|FlyBase=FBgn0037707|UniProtKB=Q9VHC0 Q9VHC0 RnpS1 PTHR15481:SF0 RIBONUCLEIC ACID BINDING PROTEIN S1 LD23870P-RELATED gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0035848|UniProtKB=Q9VSE8 Q9VSE8 Uxs PTHR43078:SF54 UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED UDP-GLUCURONIC ACID DECARBOXYLASE 1 catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 lyase#PC00144;decarboxylase#PC00089 DROME|FlyBase=FBgn0029881|UniProtKB=Q9W3Y4 Q9W3Y4 pigs PTHR46756:SF29 TRANSGELIN GAS2-LIKE PROTEIN PICKLED EGGS protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;microtubule bundle formation#GO:0001578;actin filament-based process#GO:0030029;regulation of microtubule-based process#GO:0032886;actin cytoskeleton organization#GO:0030036;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;protein localization to microtubule cytoskeleton#GO:0072698;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996 actin cytoskeleton#GO:0015629;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;stress fiber#GO:0001725;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0010213|UniProtKB=Q00637 Q00637 Sod2 PTHR11404:SF6 SUPEROXIDE DISMUTASE 2 SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0029893|UniProtKB=Q9W3X2 Q9W3X2 Dmel\CG14442 PTHR44054:SF3 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE PDZ DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0000377|UniProtKB=P17886 P17886 crn PTHR11246:SF3 PRE-MRNA SPLICING FACTOR CROOKED NECK-LIKE PROTEIN 1 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0032509|UniProtKB=Q9VJZ6 Q9VJZ6 Grx3 PTHR10293:SF74 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 inorganic ion homeostasis#GO:0098771;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;homeostatic process#GO:0042592;iron-sulfur cluster assembly#GO:0016226;intracellular iron ion homeostasis#GO:0006879;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;monoatomic ion homeostasis#GO:0050801;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034528|UniProtKB=A1ZBW6 A1ZBW6 Dmel\CG11180 PTHR23149:SF27 G PATCH DOMAIN CONTAINING PROTEIN PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030789|UniProtKB=Q8T4A9 Q8T4A9 Rrp45 PTHR11097:SF14 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP45 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;snRNA metabolic process#GO:0016073;rRNA processing#GO:0006364;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nuclear mRNA surveillance#GO:0071028;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;snRNA processing#GO:0016180;regulation of gene expression#GO:0010468;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;maturation of 5.8S rRNA#GO:0000460;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;snRNA 3'-end processing#GO:0034472;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DROME|FlyBase=FBgn0030951|UniProtKB=Q9VWR1 Q9VWR1 adf PTHR11913:SF122 COFILIN-RELATED COFILIN_ACTIN-DEPOLYMERIZING FACTOR HOMOLOG-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;actin filament depolymerization#GO:0030042 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0024273|UniProtKB=Q9VAT0 Q9VAT0 WASp PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED ACTIN NUCLEATION-PROMOTING FACTOR WAS-RELATED protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488 cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0034058|UniProtKB=Q7JZE1 Q7JZE1 Pex11ab PTHR12652:SF50 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXIN 11 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;peroxisome organization#GO:0007031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777 DROME|FlyBase=FBgn0042086|UniProtKB=Q7K2V7 Q7K2V7 Tsp42Eb PTHR19282:SF521 TETRASPANIN AT12771P-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036531|UniProtKB=Q7KUN6 Q7KUN6 Dmel\CG6244 PTHR20934:SF0 TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0029667|UniProtKB=Q8MT08 Q8MT08 Gas8 PTHR31543:SF0 DYNEIN REGULATORY COMPLEX SUBUNIT 4 DYNEIN REGULATORY COMPLEX SUBUNIT 4 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;regulation of signaling#GO:0023051;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium organization#GO:0044782;positive regulation of signaling#GO:0023056;cilium-dependent cell motility#GO:0060285;regulation of biological process#GO:0050789;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;regulation of response to stimulus#GO:0048583;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of cellular process#GO:0048522;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0030342|UniProtKB=Q9VYT5 Q9VYT5 HSP20 PTHR21664:SF1 CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66 NUDC DOMAIN-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0038524|UniProtKB=Q9VEI3 Q9VEI3 sll PTHR10778:SF13 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1 purine nucleotide transmembrane transporter activity#GO:0015216;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0032117|UniProtKB=Q9VLC1 Q9VLC1 FucTB PTHR11929:SF194 ALPHA- 1,3 -FUCOSYLTRANSFERASE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 3 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0265138|UniProtKB=P58952 P58952 Gr22c PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034114|UniProtKB=Q8T092 Q8T092 Dmel\CG4282 PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0038799|UniProtKB=Q7K2N3 Q7K2N3 VGlut2 PTHR11662:SF465 SOLUTE CARRIER FAMILY 17 SIALIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0022029|UniProtKB=Q8MQK4 Q8MQK4 l(2)k01209 PTHR10285:SF116 URIDINE KINASE URIDINE KINASE cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 DROME|FlyBase=FBgn0038852|UniProtKB=Q9VDF0 Q9VDF0 HHEX PTHR24324:SF5 HOMEOBOX PROTEIN HHEX HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0037716|UniProtKB=Q9VHB0 Q9VHB0 Son PTHR46528:SF1 PROTEIN SON PROTEIN SON binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0039868|UniProtKB=Q9V9U9 Q9V9U9 BcDNA:RE07994 PTHR13243:SF1 HSPC111 PROTEIN-RELATED NUCLEOLAR PROTEIN 16 ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0051189|UniProtKB=Q9VDF8 Q9VDF8 Dmel\CG31189 PTHR11008:SF32 PROTEIN TAKEOUT-LIKE PROTEIN GH08336P-RELATED rhythmic process#GO:0048511;circadian rhythm#GO:0007623 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0015218|UniProtKB=P48598 P48598 eIF4E1 PTHR11960:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0051704|UniProtKB=Q8IPA4 Q8IPA4 Dmel\CG31704 PTHR21131:SF0 SERINE-TYPE ENDOPEPTIDASE INHIBITOR GEO10195P1-RELATED protease inhibitor#PC00191 DROME|FlyBase=FBgn0034796|UniProtKB=Q9W1X6 Q9W1X6 c-SP48 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0035622|UniProtKB=Q9VRN1 Q9VRN1 TM9SF3 PTHR10766:SF41 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3 intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;localization within membrane#GO:0051668;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0040780|UniProtKB=Q4V6A8 Q4V6A8 Atg10 PTHR12866:SF5 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 autophagosome assembly#GO:0000045;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;glycogen catabolic process#GO:0005980;cellular component biogenesis#GO:0044085;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;carbohydrate catabolic process#GO:0016052;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;polysaccharide catabolic process#GO:0000272;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0034087|UniProtKB=A1ZAB5 A1ZAB5 clu PTHR12601:SF54 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3 CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 mitochondrion localization#GO:0051646;localization#GO:0051179;organelle localization#GO:0051640 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 DROME|FlyBase=FBgn0026324|UniProtKB=Q9XZT7 Q9XZT7 Taf10b PTHR21242:SF0 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;acetyltransferase complex#GO:1902493;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;SAGA complex#GO:0000124;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;peptidase complex#GO:1905368;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0262842|UniProtKB=M9NFG6 M9NFG6 UQCR-6.4L PTHR15420:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 6.4 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 10 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0039313|UniProtKB=Q7K025 Q7K025 Dmel\CG11892 PTHR11012:SF13 PROTEIN KINASE-LIKE DOMAIN-CONTAINING AT27361P-RELATED DROME|FlyBase=FBgn0038427|UniProtKB=Q9VEV4 Q9VEV4 ema PTHR21481:SF0 PROTEIN CLEC16A PROTEIN CLEC16A regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;cellular localization#GO:0051641;localization#GO:0051179;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of metabolic process#GO:0019222;regulation of protein-containing complex disassembly#GO:0043244;regulation of catabolic process#GO:0009894;endosomal transport#GO:0016197;regulation of macroautophagy#GO:0016241;establishment of localization#GO:0051234;transport#GO:0006810;vacuolar transport#GO:0007034;regulation of autophagosome maturation#GO:1901096;intracellular transport#GO:0046907 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 DROME|FlyBase=FBgn0032694|UniProtKB=M9PDC4 M9PDC4 MESR3 PTHR20338:SF7 NUCLEAR RESPIRATORY FACTOR 1 MISEXPRESSION SUPPRESSOR OF RAS 3, ISOFORM B cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0034865|UniProtKB=Q9W1P8 Q9W1P8 Or59b PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030162|UniProtKB=Q9W304 Q9W304 Dmel\CG1986 PTHR11610:SF203 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0036193|UniProtKB=M9PF64 M9PF64 Dmel\CG14135 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0038156|UniProtKB=Q9VFU7 Q9VFU7 side-IV PTHR23278:SF28 SIDESTEP PROTEIN SIDESTEP IV, ISOFORM C immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0044872|UniProtKB=P83088 P83088 FucTC PTHR48438:SF4 ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED ALPHA-(1,3)-FUCOSYLTRANSFERASE C DROME|FlyBase=FBgn0039115|UniProtKB=Q9VCI0 Q9VCI0 Rex2 PTHR11046:SF0 OLIGORIBONUCLEASE, MITOCHONDRIAL OLIGORIBONUCLEASE, MITOCHONDRIAL 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034432|UniProtKB=A1ZBJ2 A1ZBJ2 Acadvl PTHR43884:SF11 ACYL-COA DEHYDROGENASE VERY LONG-CHAIN ACYL-COA DEHYDROGENASE, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;lipid binding#GO:0008289;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0051755|UniProtKB=Q9VL52 Q9VL52 SoYb PTHR22655:SF2 ATP-DEPENDENT RNA HELICASE TDRD12-RELATED ATP-DEPENDENT RNA HELICASE TDRD12-RELATED primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;piRNA processing#GO:0034587;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0033069|UniProtKB=A1Z6K7 A1Z6K7 eIF3f2 PTHR10540:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F peptidase activity#GO:0008233;translation initiation factor activity#GO:0003743;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;translation initiation factor binding#GO:0031369;translation factor activity#GO:0180051;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;binding#GO:0005488 translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 eukaryotic translation initiation factor 3 complex#GO:0005852;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0031816|UniProtKB=Q9VMD4 Q9VMD4 Rchy1 PTHR21319:SF53 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 P53 pathway feedback loops 1#P04392>Pirh-2#G04684;P53 pathway feedback loops 1#P04392>Pirh-2#P04538 DROME|FlyBase=FBgn0037713|UniProtKB=Q9VHB3 Q9VHB3 CG16790 PTHR13522:SF3 U6 SNRNA PHOSPHODIESTERASE 1 U6 SNRNA PHOSPHODIESTERASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0086855|UniProtKB=Q9VPM7 Q9VPM7 anon-21Cb PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P DROME|FlyBase=FBgn0259712|UniProtKB=Q9VL64 Q9VL64 IME2 PTHR24055:SF616 MITOGEN-ACTIVATED PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 transport along microtubule#GO:0010970;establishment of localization#GO:0051234;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;organelle assembly#GO:0070925;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;signal transduction#GO:0007165;cellular process#GO:0009987;cellular localization#GO:0051641;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;cell projection organization#GO:0030030;response to stimulus#GO:0050896;signaling#GO:0023052;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0031869|UniProtKB=M9PCE3 M9PCE3 Dmel\CG18304 PTHR15742:SF5 GIRDIN GIRDIN binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039187|UniProtKB=Q8IMW9 Q8IMW9 Dmel\CG6454 PTHR37412:SF2 C2 DOMAIN-CONTAINING PROTEIN 5 C2 DOMAIN-CONTAINING PROTEIN 5 phospholipid binding#GO:0005543;metal ion binding#GO:0046872;lipid binding#GO:0008289;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;biological regulation#GO:0065007;localization within membrane#GO:0051668;regulation of establishment of protein localization#GO:0070201;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;regulation of transmembrane transport#GO:0034762;regulation of cellular process#GO:0050794;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein localization to cell periphery#GO:1990778;regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;intracellular protein transmembrane transport#GO:0065002;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;cellular process#GO:0009987;positive regulation of cellular component organization#GO:0051130;regulation of protein localization#GO:0032880;protein transport#GO:0015031;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;protein localization to membrane#GO:0072657;regulation of cellular component organization#GO:0051128 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0260012|UniProtKB=A1Z8S6 A1Z8S6 pds5 PTHR12663:SF0 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0032364|UniProtKB=Q2MGK5 Q2MGK5 Dmel\CG4970 PTHR15654:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 184 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039215|UniProtKB=Q9VC54 Q9VC54 Dmel\CG6695 PTHR13161:SF4 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT CLK4-ASSOCIATING SERINE_ARGININE RICH PROTEIN RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0015550|UniProtKB=O16867 O16867 tap PTHR19290:SF164 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED BASIC HELIX-LOOP-HELIX NEURAL TRANSCRIPTION FACTOR TAP RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0038598|UniProtKB=Q9VE97 Q9VE97 anon-WO0140519.212 PTHR31516:SF22 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 2 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;cytoplasmic microtubule#GO:0005881;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0031062|UniProtKB=Q9VWD4 Q9VWD4 CG14230 PTHR23147:SF133 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 10 nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0263974|UniProtKB=Q9VE55 Q9VE55 qin PTHR22948:SF84 TUDOR DOMAIN CONTAINING PROTEIN FI02030P-RELATED negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;cell maturation#GO:0048469;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;developmental maturation#GO:0021700;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;piRNA processing#GO:0034587;pattern specification process#GO:0007389;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;metabolic process#GO:0008152;anterior/posterior pattern specification#GO:0009952;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anterior/posterior axis specification#GO:0009948;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;embryonic pattern specification#GO:0009880;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;embryo development#GO:0009790;oogenesis#GO:0048477;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P granule#GO:0043186 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0085461|UniProtKB=A8JRH4 A8JRH4 Dmel\CG34432 PTHR41152:SF8 AT26438P-RELATED AT26438P-RELATED DROME|FlyBase=FBgn0039350|UniProtKB=Q9VBP5 Q9VBP5 jigr1 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0030768|UniProtKB=Q9VXD6 Q9VXD6 Nemp PTHR13598:SF1 AT07567P-RELATED AT07567P-RELATED intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967 DROME|FlyBase=FBgn0038950|UniProtKB=Q9VD26 Q9VD26 CG5382 PTHR12981:SF0 ZINC FINGER PROTEIN-LIKE 1 ZINC FINGER PROTEIN-LIKE 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0036207|UniProtKB=Q9VTN7 Q9VTN7 Dmel\CG10907 PTHR45625:SF6 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 chaperone#PC00072 DROME|FlyBase=FBgn0040551|UniProtKB=Q9VFX9 Q9VFX9 Dmel\CG11686 PTHR39948:SF1 GEO11419P1 GEO11419P1 DROME|FlyBase=FBgn0035971|UniProtKB=Q9VSV4 Q9VSV4 Dmel\CG4477 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0005771|UniProtKB=Q24423 Q24423 noc PTHR12522:SF5 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN NOC negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0035513|UniProtKB=Q9VZF9 Q9VZF9 Cpr64Ad PTHR12236:SF99 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 64AD extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053120|UniProtKB=Q9VJ41 Q9VJ41 Dmel\CG33120 PTHR31650:SF23 O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN GH11223P acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 biosynthetic process#GO:0009058;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0261575|UniProtKB=Q9VBR6 Q9VBR6 tobi PTHR43053:SF4 GLYCOSIDASE FAMILY 31 RE74917P hydrolase#PC00121;glucosidase#PC00108;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0033816|UniProtKB=A1Z9A8 A1Z9A8 Ptcd3 PTHR16276:SF1 PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3 SMALL RIBOSOMAL SUBUNIT PROTEIN MS39 ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0038646|UniProtKB=Q9VE39 Q9VE39 Dmel\CG7715 PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0034399|UniProtKB=Q7JYX3 Q7JYX3 Dmel\CG15083 PTHR34609:SF17 GEO08273P1-RELATED MARVEL DOMAIN-CONTAINING PROTEIN 3 DROME|FlyBase=FBgn0034986|UniProtKB=Q9W199 Q9W199 mRpS17 PTHR24088:SF0 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US17M organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202 DROME|FlyBase=FBgn0036028|UniProtKB=Q9VT29 Q9VT29 Mpped PTHR12905:SF0 METALLOPHOSPHOESTERASE CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 DROME|FlyBase=FBgn0038084|UniProtKB=Q9VG28 Q9VG28 beat-Vc PTHR21261:SF5 BEAT PROTEIN BEATEN PATH VA, ISOFORM A-RELATED intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0037999|UniProtKB=Q9VGC2 Q9VGC2 Dmel\CG4860 PTHR43884:SF42 ACYL-COA DEHYDROGENASE SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;short-chain fatty acid catabolic process#GO:0019626;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0053300|UniProtKB=Q7KTF6 Q7KTF6 Muc30E PTHR35383:SF1 MUCIN 12EA-RELATED MUCIN 30E DROME|FlyBase=FBgn0001220|UniProtKB=P29845 P29845 Hsc70-5 PTHR19375:SF184 HEAT SHOCK PROTEIN 70KDA STRESS-70 PROTEIN, MITOCHONDRIAL ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;protein refolding#GO:0042026;iron-sulfur cluster assembly#GO:0016226;protein folding#GO:0006457;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208 DROME|FlyBase=FBgn0039705|UniProtKB=B7Z0R7 B7Z0R7 Atg16 PTHR19878:SF19 AUTOPHAGY PROTEIN 16-LIKE AUTOPHAGY-RELATED 16, ISOFORM F protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macroautophagy#GO:0016236;cellular component assembly#GO:0022607;catabolic process#GO:0009056;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;metabolic process#GO:0008152 vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;autophagosome#GO:0005776 DROME|FlyBase=FBgn0038679|UniProtKB=Q9VE02 Q9VE02 Dmel\CG6040 PTHR37970:SF1 PROTEIN CBG08587 SERINE-RICH ADHESIN FOR PLATELETS DROME|FlyBase=FBgn0031678|UniProtKB=Q9VMU6 Q9VMU6 Nepl3 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0000140|UniProtKB=Q9VC45 Q9VC45 asp PTHR22706:SF1 ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES binding#GO:0005488;calmodulin binding#GO:0005516;protein binding#GO:0005515 organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;meiotic cell cycle#GO:0051321;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cell cycle#GO:0007049;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;reproductive process#GO:0022414;organelle localization#GO:0051640;sexual reproduction#GO:0019953;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;spindle localization#GO:0051653 microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0035983|UniProtKB=Q9VSX7 Q9VSX7 Dmel\CG4080 PTHR45981:SF11 LD02310P LD02310P aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;signaling receptor binding#GO:0005102;MHC protein binding#GO:0042287;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;antigen processing and presentation#GO:0019882;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;early endosome membrane#GO:0031901;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vesicle membrane#GO:0012506 DROME|FlyBase=FBgn0021967|UniProtKB=Q9VQR2 Q9VQR2 ND-PDSW PTHR13094:SF1 NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 DROME|FlyBase=FBgn0051077|UniProtKB=Q8IMQ3 Q8IMQ3 Dmel\CG31077 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0031214|UniProtKB=Q9VPI7 Q9VPI7 Dmel\CG11374 PTHR11346:SF196 GALECTIN GALECTIN carbohydrate binding#GO:0030246;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0039758|UniProtKB=Q9VA88 Q9VA88 c-SP5 PTHR24260:SF144 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED Toll pathway-drosophila#P06217>SPE#P06340 DROME|FlyBase=FBgn0028888|UniProtKB=Q9VJQ0 Q9VJQ0 BG:DS03192.2 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0030360|UniProtKB=Q9VYR3 Q9VYR3 Dmel\CG1806 PTHR15260:SF1 SARCOSPAN SARCOSPAN membrane#GO:0016020;cell periphery#GO:0071944;sarcolemma#GO:0042383;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0001258|UniProtKB=Q95028 Q95028 Ldh PTHR43128:SF34 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034387|UniProtKB=Q9V8M2 Q9V8M2 Cyp12b2 PTHR24305:SF238 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0261792|UniProtKB=Q9VE17 Q9VE17 snRNP-U1-C PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;U1 snRNP#GO:0005685;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 DROME|FlyBase=FBgn0051992|UniProtKB=Q8SY33 Q8SY33 gw PTHR13020:SF25 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 PROTEIN GAWKY negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030801|UniProtKB=Q9VX99 Q9VX99 Polr3I PTHR15561:SF0 CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0085464|UniProtKB=Q9W4B1 Q9W4B1 Dmel\CG34435 PTHR23048:SF0 MYOSIN LIGHT CHAIN 1, 3 FI08416P-RELATED membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0032647|UniProtKB=Q9VJC5 Q9VJC5 Dmel\CG15143 PTHR22455:SF10 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 DROME|FlyBase=FBgn0261089|UniProtKB=C0HDP4 C0HDP4 Sytalpha PTHR10024:SF373 SYNAPTOTAGMIN MIP05618P molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149 chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;regulation of exocytosis#GO:0017157;positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular component organization#GO:0051128;regulation of synaptic vesicle exocytosis#GO:2000300;export from cell#GO:0140352;signaling#GO:0023052;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;synaptic signaling#GO:0099536;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887 organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;plasma membrane#GO:0005886;axon#GO:0030424;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0051213|UniProtKB=Q9VDR4 Q9VDR4 CG11460 PTHR19229:SF280 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP BINDING CASSETTE SUBFAMILY A MEMBER 8-RELATED ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0033252|UniProtKB=A0A0B4LFS0 A0A0B4LFS0 Dmel\CG12769 PTHR24404:SF78 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZTF-16 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0003559|UniProtKB=P25991 P25991 su(f) PTHR19980:SF0 RNA CLEAVAGE STIMULATION FACTOR CLEAVAGE STIMULATION FACTOR SUBUNIT 3 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0051326|UniProtKB=Q8ING0 Q8ING0 CG9645 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0036374|UniProtKB=Q9VU86 Q9VU86 Spt20 PTHR13526:SF8 TRANSCRIPTION FACTOR SPT20 HOMOLOG SPT20 HOMOLOG, SAGA COMPLEX COMPONENT-RELATED transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0031676|UniProtKB=Q9VMU8 Q9VMU8 senju PTHR10231:SF50 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSPORTER SENJU transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;UDP-galactose transmembrane transporter activity#GO:0005459;organophosphate ester transmembrane transporter activity#GO:0015605 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transporter#PC00227 DROME|FlyBase=FBgn0050284|UniProtKB=Q8MLV6 Q8MLV6 BcDNA:AT12437 PTHR23319:SF4 GRAM DOMAIN CONTAINING 1B, ISOFORM E AT22714P-RELATED steroid binding#GO:0005496;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;binding#GO:0005488;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;sterol binding#GO:0032934 organic hydroxy compound transport#GO:0015850;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;lipid localization#GO:0010876;intracellular transport#GO:0046907;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;organelle membrane contact site#GO:0044232;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 DROME|FlyBase=FBgn0038462|UniProtKB=Q9VEQ1 Q9VEQ1 EMC2A PTHR12760:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;EMC complex#GO:0072546;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0025682|UniProtKB=Q9W0H8 Q9W0H8 scf PTHR10827:SF52 RETICULOCALBIN RETICULOCALBIN-3 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0000659|UniProtKB=P14734 P14734 fkh PTHR11829:SF380 FORKHEAD BOX PROTEIN PROTEIN FORK HEAD sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0064237|UniProtKB=Q8T0R7 Q8T0R7 Idgf5 PTHR11177:SF235 CHITINASE CHITINASE-LIKE PROTEIN IDGF1-RELATED hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034636|UniProtKB=D5SHR0 D5SHR0 twz PTHR14499:SF67 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN TIWAZ transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0027338|UniProtKB=Q9V455 Q9V455 Kap-alpha3 PTHR23316:SF28 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 DROME|FlyBase=FBgn0033170|UniProtKB=Q6XPX3 Q6XPX3 sPLA2 PTHR12253:SF43 RH14732P PHOSPHOLIPASE A2 A2-type glycerophospholipase activity#GO:0004623;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298 DROME|FlyBase=FBgn0036910|UniProtKB=Q9VW43 Q9VW43 Cyp305a1 PTHR24303:SF13 HEME-BINDING MONOOXYGENASE FAMILY CYTOCHROME P450 303A1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034928|UniProtKB=A0A0B4K8B1 A0A0B4K8B1 Dmel\CG13562 PTHR11610:SF104 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0050462|UniProtKB=Q7JV41 Q7JV41 ste24c PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 metalloprotease#PC00153 DROME|FlyBase=FBgn0030695|UniProtKB=Q9VXN9 Q9VXN9 PGRP-LE PTHR11022:SF80 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;peptidoglycan muralytic activity#GO:0061783;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;defense response#GO:0006952;response to external stimulus#GO:0009605 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0036486|UniProtKB=Q9VUM0 Q9VUM0 Msh6 PTHR11361:SF148 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH6 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0050440|UniProtKB=Q7K4E0 Q7K4E0 CG12183 PTHR22826:SF211 RHO GUANINE EXCHANGE FACTOR-RELATED LD43457P guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0010551|UniProtKB=A8DYI6 A8DYI6 Phb2 PTHR23222:SF1 PROHIBITIN PROHIBITIN-2 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0033853|UniProtKB=Q6IDH2 Q6IDH2 Nadk1a PTHR20275:SF44 NAD KINASE NAD KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172 DROME|FlyBase=FBgn0086355|UniProtKB=P29613 P29613 Tpi PTHR21139:SF2 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861 glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;nucleoside diphosphate catabolic process#GO:0009134;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;glyceraldehyde-3-phosphate metabolic process#GO:0019682;oxoacid metabolic process#GO:0043436 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Triosephosphate isomerase#P00673 DROME|FlyBase=FBgn0051522|UniProtKB=A0A0B4KF65 A0A0B4KF65 BcDNA:GH22993 PTHR11157:SF167 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0028848|UniProtKB=Q7KTA9 Q7KTA9 Gpo3 PTHR11985:SF15 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 dehydrogenase#PC00092 DROME|FlyBase=FBgn0038251|UniProtKB=Q8INF6 Q8INF6 Hexim PTHR13469:SF8 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 HEXIM P-TEFB COMPLEX SUBUNIT 1 protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase inhibitor activity#GO:0004860;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;snRNA binding#GO:0017069;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DROME|FlyBase=FBgn0023197|UniProtKB=M9MS20 M9MS20 Jon74E PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0035567|UniProtKB=Q9VZ94 Q9VZ94 Dmel\CG7514 PTHR45618:SF9 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL 2-OXOGLUTARATE_MALATE CARRIER PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0037607|UniProtKB=Q9VHN7 Q9VHN7 Tkt PTHR43195:SF1 TRANSKETOLASE TRANSKETOLASE ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;transketolase activity#GO:0004802;cation binding#GO:0043169;transferase activity#GO:0016740;catalytic activity#GO:0003824;transketolase or transaldolase activity#GO:0016744;heterocyclic compound binding#GO:1901363 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transketolase#PC00221;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0033352|UniProtKB=A1Z7K9 A1Z7K9 PAN2 PTHR15728:SF0 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468 P-body#GO:0000932;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 exoribonuclease#PC00099 DROME|FlyBase=FBgn0050147|UniProtKB=Q0E908 Q0E908 Hil PTHR47020:SF1 HILLARIN HILLARIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0026431|UniProtKB=Q9VKU7 Q9VKU7 Grip75 PTHR19302:SF27 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 4 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122;reproductive process#GO:0022414;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0015524|UniProtKB=P56672 P56672 otp PTHR46770:SF1 HOMEOBOX PROTEIN ORTHOPEDIA HOMEOBOX PROTEIN ORTHOPEDIA binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 neurogenesis#GO:0022008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;generation of neurons#GO:0048699;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;cellular process#GO:0009987 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0053767|UniProtKB=Q4ABH9 Q4ABH9 CG14458 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0000658|UniProtKB=P54360 P54360 fj PTHR13147:SF5 FOUR-JOINTED BOX PROTEIN 1 FOUR-JOINTED BOX PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular process#GO:0009987 DROME|FlyBase=FBgn0015521|UniProtKB=O76927 O76927 RpS21 PTHR10442:SF0 40S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN ES21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;protein metabolic process#GO:0019538;translation#GO:0006412 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0030400|UniProtKB=B7Z143 B7Z143 Pits PTHR10816:SF19 MYELIN TRANSCRIPTION FACTOR 1-RELATED PROTEIN INTERACTING WITH TTK69 AND SIN3A, ISOFORM D transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0026630|UniProtKB=Q9VVX5 Q9VVX5 nes PTHR13906:SF14 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine biosynthetic process#GO:0006656;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid modification#GO:0030258 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 DROME|FlyBase=FBgn0063485|UniProtKB=Q8I7C3 Q8I7C3 Lasp PTHR46218:SF4 LASP LIM AND SH3 DOMAIN PROTEIN LASP protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 DROME|FlyBase=FBgn0034363|UniProtKB=Q7JY26 Q7JY26 Dmel\CG5327 PTHR21096:SF0 PROTEIN FAM136A TIM DOUBLE TWIN CX3C MOTIF PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0052343|UniProtKB=M9NFF9 M9NFF9 Atac3 PTHR24193:SF132 ANKYRIN REPEAT PROTEIN ADA2A-CONTAINING COMPLEX COMPONENT 3, ISOFORM D sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0050281|UniProtKB=Q95SM8 Q95SM8 CG6676 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0014011|UniProtKB=P48554 P48554 Rac2 PTHR24072:SF411 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;neurogenesis#GO:0022008;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;neuron differentiation#GO:0030182;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection assembly#GO:0030031;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;cell morphogenesis involved in neuron differentiation#GO:0048667;cortical cytoskeleton organization#GO:0030865;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731;supramolecular fiber organization#GO:0097435;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of developmental process#GO:0050793;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;Rac protein signal transduction#GO:0016601;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;cell differentiation#GO:0030154;cell projection organization#GO:0030030;signaling#GO:0023052;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 G-protein#PC00020;small GTPase#PC00208 Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by netrin#P00009>Rac#P00366;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;Integrin signalling pathway#P00034>Rac#P00927;Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;T cell activation#P00053>rac#P01324;EGF receptor signaling pathway#P00018>Rac#P00564;FGF signaling pathway#P00021>Rac#P00645 DROME|FlyBase=FBgn0030877|UniProtKB=Q9VX09 Q9VX09 Arp8 PTHR11937:SF13 ACTIN ACTIN-RELATED PROTEIN 8 structural constituent of cytoskeleton#GO:0005200;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974 actin and actin related protein#PC00039 DROME|FlyBase=FBgn0022768|UniProtKB=Q9W4H8 Q9W4H8 Pp2C1 PTHR47992:SF253 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1D phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;protein binding#GO:0005515;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;mitogen-activated protein kinase binding#GO:0051019;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;chromatin organization#GO:0006325;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway feedback loops 2#P04398>WIP-1#G04708;p53 pathway#P00059>WIP-1#G04693;p53 pathway feedback loops 2#P04398>WIP-1#P04650 DROME|FlyBase=FBgn0031431|UniProtKB=Q9VQD1 Q9VQD1 Dmel\CG3515 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 binding#GO:0005488;chromatin binding#GO:0003682 methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0026320|UniProtKB=Q9V3S6 Q9V3S6 Tom PTHR12254:SF0 ENHANCER OF SPLIT MALPHA PROTEIN BARBU-RELATED DROME|FlyBase=FBgn0040333|UniProtKB=X2JI61 X2JI61 brv3 PTHR10877:SF183 POLYCYSTIN FAMILY MEMBER AT14535P-RELATED ion channel#PC00133 DROME|FlyBase=FBgn0037356|UniProtKB=Q9VNF5 Q9VNF5 anon-WO0118547.367 PTHR11712:SF362 POLYKETIDE SYNTHASE-RELATED 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 DROME|FlyBase=FBgn0034286|UniProtKB=A1ZB15 A1ZB15 dpr13 PTHR23279:SF37 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 13, ISOFORM B cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253 DROME|Gene_ORFName=Dmel_CG46516|UniProtKB=A0ACD4DAU8 A0ACD4DAU8 CG46516 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component assembly#GO:0022607;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-containing complex organization#GO:0043933;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0011232|UniProtKB=Q9VLC0 Q9VLC0 scat PTHR12965:SF0 VACUOLAR PROTEIN SORTING 54 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515;syntaxin binding#GO:0019905 localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0040368|UniProtKB=Q9W5B3 Q9W5B3 eIF4E7 PTHR11960:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0030529|UniProtKB=Q9VY78 Q9VY78 Clic PTHR43920:SF11 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL CLIC monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820;transport#GO:0006810 intracellular anatomical structure#GO:0005622;apical part of cell#GO:0045177;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;apical plasma membrane#GO:0016324 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0039218|UniProtKB=Q9VC49 Q9VC49 Polr2L PTHR23431:SF3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;zinc ion binding#GO:0008270;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase I#GO:0006360;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;organelle#GO:0043226 DNA metabolism protein#PC00009 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 DROME|FlyBase=FBgn0040794|UniProtKB=Q9VV37 Q9VV37 Dmel\CG13056 PTHR34931:SF4 FI02976P-RELATED GEO13385P1-RELATED DROME|FlyBase=FBgn0066304|UniProtKB=Q2MGL3 Q2MGL3 Rpp20 PTHR15314:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P20 RIBONUCLEASE P PROTEIN SUBUNIT P20 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;endoribonuclease#PC00094 DROME|FlyBase=FBgn0031637|UniProtKB=Q9VR35 Q9VR35 mxt PTHR20849:SF2 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN MEXTLI EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN MEXTLI translation factor activity#GO:0180051;binding#GO:0005488;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation initiation factor binding#GO:0031369 regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;positive regulation of translation#GO:0045727;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0025724|UniProtKB=O62621 O62621 beta'COP PTHR19876:SF2 COATOMER COATOMER SUBUNIT BETA' retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0053752|UniProtKB=A1Z922 A1Z922 Dmel\CG33752 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0034785|UniProtKB=Q9W1Y9 Q9W1Y9 Dmel\CG3649 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0005658|UniProtKB=P29774 P29774 Ets65A PTHR11849:SF304 ETS DNA-BINDING PROTEIN D-ETS-3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0031950|UniProtKB=Q9VLW9 Q9VLW9 Herp PTHR12943:SF27 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-INDUCED ENDOPLASMIC RETICULUM PROTEIN, ISOFORM A response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987 DROME|FlyBase=FBgn0030773|UniProtKB=Q9VXC9 Q9VXC9 SP99 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0260941|UniProtKB=A2VEY9 A2VEY9 app PTHR22883:SF43 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE APP catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036623|UniProtKB=D5AEK7 D5AEK7 Agpat3 PTHR10983:SF24 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 3, ISOFORM E-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0052436|UniProtKB=Q9VP43 Q9VP43 CG12973 PTHR40552:SF6 AT05186P-RELATED FI09606P-RELATED DROME|FlyBase=FBgn0033112|UniProtKB=A1Z6R3 A1Z6R3 Spn42Db PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0033212|UniProtKB=A0A0B4KEE7 A0A0B4KEE7 LRR PTHR24112:SF69 LEUCINE-RICH REPEAT, ISOFORM F-RELATED LEUCINE-RICH REPEAT, ISOFORM F regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;regulation of organelle organization#GO:0033043;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cell migration#GO:0016477;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0045469|UniProtKB=Q9VD74 Q9VD74 Gr93c PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031116|UniProtKB=Q8IQ31 Q8IQ31 Dmel\CG1695 PTHR22957:SF502 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0002937|UniProtKB=Q9VFS2 Q9VFS2 ninaB PTHR10543:SF152 BETA-CAROTENE DIOXYGENASE CAROTENOID ISOMEROOXYGENASE catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 retinoid metabolic process#GO:0001523;isoprenoid metabolic process#GO:0006720;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;catabolic process#GO:0009056;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987 oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0262874|UniProtKB=M9NFC6 M9NFC6 chrX_18032634_18033088.0 PTHR23259:SF84 RIDDLE TIL DOMAIN-CONTAINING PROTEIN protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0250755|UniProtKB=Q9V9T1 Q9V9T1 CG2112 PTHR15574:SF43 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 5 negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;negative regulation of metabolic process#GO:0009892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0265416|UniProtKB=G4LU05 G4LU05 Neto PTHR24251:SF28 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE, ISOFORM B protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0040228|UniProtKB=Q9VJQ6 Q9VJQ6 DCTN5-p25 PTHR46126:SF1 DYNACTIN SUBUNIT 5 DYNACTIN SUBUNIT 5 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629 microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0000477|UniProtKB=Q9VED8 Q9VED8 DNaseII PTHR10858:SF23 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE II catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056 endodeoxyribonuclease#PC00093 DROME|FlyBase=FBgn0031598|UniProtKB=Q9VQY8 Q9VQY8 Vps53 PTHR12820:SF0 VACUOLAR SORTING PROTEIN 53 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0039172|UniProtKB=Q9VCA9 Q9VCA9 Spase22-23 PTHR12804:SF0 MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23 SIGNAL PEPTIDASE COMPLEX SUBUNIT 3 protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;protein targeting#GO:0006605;metabolic process#GO:0008152;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;protein targeting to ER#GO:0045047;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of protein localization#GO:0045184;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 DROME|FlyBase=FBgn0034476|UniProtKB=Q7KIN0 Q7KIN0 Toll-7 PTHR24373:SF385 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN GH01279P-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0264707|UniProtKB=Q9W0S2 Q9W0S2 RhoGEF3 PTHR45834:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0024251|UniProtKB=O61348 O61348 bbx PTHR13059:SF10 HMG-BOX TRANSCRIPTION FACTOR BBX HMG BOX TRANSCRIPTION FACTOR BBX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0260962|UniProtKB=Q9XYZ5 Q9XYZ5 pic PTHR10644:SF27 DNA REPAIR/RNA PROCESSING CPSF FAMILY DNA DAMAGE-BINDING PROTEIN 1 modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;response to stimulus#GO:0050896;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;nucleobase-containing compound metabolic process#GO:0006139 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0022069|UniProtKB=Q9VJZ7 Q9VJZ7 Nnp-1 PTHR13026:SF0 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING 1B transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0000241|UniProtKB=P12428 P12428 bw PTHR48041:SF116 ABC TRANSPORTER G FAMILY MEMBER 28 PROTEIN BROWN transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0053483|UniProtKB=A0A0B4JDE6 A0A0B4JDE6 Dmel\CG33483 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0083976|UniProtKB=Q0E8K6 Q0E8K6 Dmel\CG34140 PTHR11142:SF33 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE SYNTHASE-LIKE 1 catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;pseudouridine synthesis#GO:0001522;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 lyase#PC00144 DROME|FlyBase=FBgn0034920|UniProtKB=Q9W1H6 Q9W1H6 Dmel\CG5597 PTHR21261:SF8 BEAT PROTEIN BEATEN PATH IA, ISOFORM B-RELATED motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0260798|UniProtKB=P32865 P32865 Gprk1 PTHR24355:SF18 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;G protein-coupled receptor binding#GO:0001664;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 G protein-coupled receptor signaling pathway#GO:0007186;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cell communication#GO:0010646 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin kinase#P00750;Parkinson disease#P00049>GRK#P01234;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK3#P05941 DROME|FlyBase=FBgn0035262|UniProtKB=Q9W099 Q9W099 Dmel\CG18171 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0025680|UniProtKB=O77059 O77059 cry PTHR11455:SF17 CRYPTOCHROME CRYPTOCHROME-1 lyase activity#GO:0016829;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;carbon-carbon lyase activity#GO:0016830;DNA binding#GO:0003677;deoxyribodipyrimidine photo-lyase activity#GO:0003904;nucleic acid binding#GO:0003676;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;response to radiation#GO:0009314;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;rhythmic process#GO:0048511;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01501;Circadian clock system#P00015>cry#G01497 DROME|FlyBase=FBgn0033740|UniProtKB=Q7K4B4 Q7K4B4 dgt5 PTHR34491:SF156 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED AUGMIN COMPLEX SUBUNIT DGT5 DROME|FlyBase=FBgn0053246|UniProtKB=Q7KV22 Q7KV22 Ste:CG33246 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;serine/threonine protein kinase complex#GO:1902554 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0034094|UniProtKB=A1ZAC0 A1ZAC0 Tsf3 PTHR11485:SF54 TRANSFERRIN TRANSFERRIN transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transport#GO:0006826;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001 intracellular organelle#GO:0043229;extracellular region#GO:0005576;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;recycling endosome#GO:0055037;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0030362|UniProtKB=Q76NR6 Q76NR6 regucalcin PTHR10907:SF66 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 esterase#PC00097;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034281|UniProtKB=A1ZB08 A1ZB08 Dmel\CG14490 PTHR46511:SF1 MORN REPEAT-CONTAINING PROTEIN 3 MORN REPEAT-CONTAINING PROTEIN 3 DROME|FlyBase=FBgn0052376|UniProtKB=Q8IQ89 Q8IQ89 Dmel\CG32376 PTHR24276:SF97 POLYSERASE-RELATED GH13245P2-RELATED catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0086605|UniProtKB=Q9VN19 Q9VN19 CG9853 PTHR12875:SF3 GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;protein localization to organelle#GO:0033365 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0030721|UniProtKB=Q9VXK3 Q9VXK3 Dmel\CG12698 PTHR23011:SF41 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4-LIKE DROME|FlyBase=FBgn0290418|UniProtKB=Q7KRZ3 Q7KRZ3 Exo84 PTHR21426:SF12 EXOCYST COMPLEX COMPONENT 8 EXOCYST COMPLEX COMPONENT 8 localization within membrane#GO:0051668;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;post-Golgi vesicle-mediated transport#GO:0006892;macromolecule localization#GO:0033036;cellular process#GO:0009987;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938 DROME|FlyBase=FBgn0026375|UniProtKB=Q9VX32 Q9VX32 RhoGAPp190 PTHR46005:SF4 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 190 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of axonogenesis#GO:0050770;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of anatomical structure size#GO:0090066;regulation of cell projection organization#GO:0031344;signaling#GO:0023052;regulation of developmental process#GO:0050793;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;regulation of cell size#GO:0008361;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 DROME|FlyBase=FBgn0034008|UniProtKB=Q9V7A7 Q9V7A7 CG8152 PTHR20923:SF1 BAT4 PROTEIN-RELATED G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0035691|UniProtKB=Q9VRV6 Q9VRV6 Dmel\CG7386 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0035068|UniProtKB=Q9W101 Q9W101 Dmel\CG12849 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0001122|UniProtKB=P16378 P16378 Galphao PTHR10218:SF362 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA O SUBUNIT ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 heterotrimeric G-protein#PC00117;G-protein#PC00020 Opioid prodynorphin pathway#P05916>G-protein#P06002;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085 DROME|FlyBase=FBgn0013678|UniProtKB=P18935 P18935 mt:Cyt-b PTHR19271:SF42 CYTOCHROME B CYTOCHROME B proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324 electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex III#GO:0045275;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0032015|UniProtKB=Q8SY53 Q8SY53 Ostgamma PTHR12692:SF8 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED GH11935P localization#GO:0051179;monoatomic cation transport#GO:0006812;protein metabolic process#GO:0019538;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;metal ion transport#GO:0030001;metabolic process#GO:0008152;magnesium ion transport#GO:0015693;glycoprotein metabolic process#GO:0009100;transport#GO:0006810;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;establishment of localization#GO:0051234;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0085397|UniProtKB=A0A6M3Q7U5 A0A6M3Q7U5 Fili PTHR24373:SF413 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN FISH-LIPS, ISOFORM E signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0051876|UniProtKB=Q8IPD8 Q8IPD8 Cpr30F PTHR12236:SF46 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 30B-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0032151|UniProtKB=Q7KTF8 Q7KTF8 nAChRalpha6 PTHR18945:SF876 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA6, ISOFORM E ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 DROME|FlyBase=FBgn0050093|UniProtKB=Q4QPY7 Q4QPY7 COX6AL PTHR11504:SF9 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT 6A-LIKE enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidase#PC00175 DROME|FlyBase=FBgn0013325|UniProtKB=P46222 P46222 RpL11 PTHR11994:SF8 60S RIBOSOMAL PROTEIN L11-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL5 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0030558|UniProtKB=Q9VY42 Q9VY42 Tat PTHR45744:SF46 TYROSINE AMINOTRANSFERASE TYROSINE AMINOTRANSFERASE transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 transaminase#PC00216 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213 DROME|FlyBase=FBgn0289933|UniProtKB=P11046 P11046 LanB1 PTHR10574:SF375 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cell migration#GO:0016477;extracellular matrix assembly#GO:0085029;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;cell motility#GO:0048870;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular component assembly#GO:0022607;cell adhesion#GO:0007155;generation of neurons#GO:0048699;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 DROME|FlyBase=FBgn0259178|UniProtKB=B7Z0Q2 B7Z0Q2 5PtaseI PTHR12997:SF2 TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE INOSITOL POLYPHOSPHATE-5-PHOSPHATASE A hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phosphatase#PC00181;hydrolase#PC00121 PI3 kinase pathway#P00048>SHIP#P01200 DROME|FlyBase=FBgn0011570|UniProtKB=P48603 P48603 cpb PTHR10619:SF0 F-ACTIN-CAPPING PROTEIN SUBUNIT BETA F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament organization#GO:0110053;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0023143|UniProtKB=Q8T0L3 Q8T0L3 Uba1 PTHR10953:SF4 UBIQUITIN-ACTIVATING ENZYME E1 E1 UBIQUITIN-ACTIVATING ENZYME thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 DROME|FlyBase=FBgn0032473|UniProtKB=Q9VK36 Q9VK36 kmg PTHR24403:SF94 ZINC FINGER PROTEIN KUMGANG binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0024734|UniProtKB=O61722 O61722 PRL-1 PTHR23339:SF98 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PRL-1 PHOSPHATASE protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DROME|FlyBase=FBgn0030520|UniProtKB=Q9VY91 Q9VY91 Pdcd4 PTHR12626:SF15 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation factor#PC00223 DROME|FlyBase=FBgn0259958|UniProtKB=B4ZJ93 B4ZJ93 Sfp24F PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0086758|UniProtKB=Q9VQ30 Q9VQ30 chinmo PTHR23110:SF94 BTB DOMAIN TRANSCRIPTION FACTOR ZINC FINGER PROTEIN CHINMO regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0034472|UniProtKB=Q7K037 Q7K037 mtr PTHR43601:SF39 THIOREDOXIN, MITOCHONDRIAL THIOREDOXIN, MITOCHONDRIAL cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 DROME|FlyBase=FBgn0050471|UniProtKB=F7VJS4 F7VJS4 CG30471-RA PTHR11161:SF15 O-ACYLTRANSFERASE GH19286P-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0262008|UniProtKB=M9MS27 M9MS27 Dmel\CG42826 PTHR23529:SF2 GH19118P-RELATED GH19118P-RELATED DROME|FlyBase=FBgn0053983|UniProtKB=Q7KUN4 Q7KUN4 obst-H PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0025334|UniProtKB=Q9W1H7 Q9W1H7 PHDP PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0086656|UniProtKB=Q8T0Q4 Q8T0Q4 shrb PTHR22761:SF10 CHARGED MULTIVESICULAR BODY PROTEIN BCDNA.GH08385-RELATED endosomal transport#GO:0016197;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;nuclear membrane organization#GO:0071763;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;localization#GO:0051179;cellular localization#GO:0051641;late endosome to vacuole transport#GO:0045324;membrane assembly#GO:0071709;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic side of plasma membrane#GO:0009898;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;vesicle#GO:0031982;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;cell periphery#GO:0071944;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic side of membrane#GO:0098562 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0003900|UniProtKB=P10627 P10627 twi PTHR23349:SF50 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST PROTEIN TWIST sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0259823|UniProtKB=Q9VFA8 Q9VFA8 lincRNA.S6902 PTHR15256:SF6 INTEGRAL MEMBRANE PROTEIN DGCR2/IDD INTEGRAL MEMBRANE PROTEIN DGCR2_IDD cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0263048|UniProtKB=Q8IN06 Q8IN06 Gpdh3 PTHR11728:SF8 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0034946|UniProtKB=Q2MGN0 Q2MGN0 Dmel\CG3065 PTHR23235:SF165 KRUEPPEL-LIKE TRANSCRIPTION FACTOR FI01014P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0003751|UniProtKB=Q24155 Q24155 trk PTHR39940:SF4 PROTHORACICOTROPIC HORMONE, ISOFORM F PROTEIN TRUNK molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 biological regulation#GO:0065007;regulation of lipid biosynthetic process#GO:0046890;regulation of steroid biosynthetic process#GO:0050810;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of lipid metabolic process#GO:0019216 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 DROME|FlyBase=FBgn0030102|UniProtKB=Q9W373 Q9W373 SmydA-9 PTHR46455:SF3 SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 9, ISOFORM A-RELATED organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0032703|UniProtKB=Q9VJ60 Q9VJ60 Dmel\CG10343 PTHR21275:SF1 RWD DOMAIN-CONTAINING PROTEIN 4 RWD DOMAIN-CONTAINING PROTEIN 4 DROME|FlyBase=FBgn0034943|UniProtKB=Q9W1E9 Q9W1E9 Fmo1 PTHR43539:SF100 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FLAVIN-CONTAINING MONOOXYGENASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0052383|UniProtKB=Q8IQ79 Q8IQ79 sphinx1 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0038056|UniProtKB=Q9VG61 Q9VG61 Dmel\CG5961 PTHR12874:SF29 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 9 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 DROME|FlyBase=FBgn0033527|UniProtKB=Q8MKJ6 Q8MKJ6 cg11777 PTHR45625:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|FlyBase=FBgn0001269|UniProtKB=P05527 P05527 inv PTHR24341:SF6 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN INVECTED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 DROME|FlyBase=FBgn0030364|UniProtKB=Q9VYR0 Q9VYR0 Lsm12a PTHR13542:SF0 LSM12 HOMOLOG PROTEIN LSM12 DROME|FlyBase=FBgn0039466|UniProtKB=Q9VB98 Q9VB98 CG5521 PTHR10063:SF11 TUBERIN RHO GTPASE-ACTIVATING PROTEIN CG5521-RELATED enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 GTPase-activating protein#PC00257;G-protein modulator#PC00022 DROME|FlyBase=FBgn0038200|UniProtKB=Q9VFN5 Q9VFN5 anon-WO0140519.48 PTHR10772:SF67 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;protein-folding chaperone binding#GO:0051087 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 chaperonin#PC00073 DROME|FlyBase=FBgn0036515|UniProtKB=Q9VUR3 Q9VUR3 AIMP2 PTHR13438:SF2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0040319|UniProtKB=Q9W3K5 Q9W3K5 Gclc PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518 catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;ligase#PC00142 DROME|FlyBase=FBgn0045443|UniProtKB=P83118 P83118 mthl11 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0029153|UniProtKB=A1ZAF6 A1ZAF6 Menl-2 PTHR23406:SF101 MALIC ENZYME-RELATED MALIC ENZYME-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 DROME|FlyBase=FBgn0035975|UniProtKB=Q95T64 Q95T64 PGRP-LA PTHR11022:SF76 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;pattern recognition receptor activity#GO:0038187;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;peptidoglycan muralytic activity#GO:0061783;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0034270|UniProtKB=Q7JUM3 Q7JUM3 PIG-A PTHR45871:SF1 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827 DROME|FlyBase=FBgn0040512|UniProtKB=Q9VV89 Q9VV89 zetaCOP PTHR11043:SF0 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA intra-Golgi vesicle-mediated transport#GO:0006891;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 vesicle membrane#GO:0012506;membrane#GO:0016020;COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle coat#GO:0030120;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135 vesicle coat protein#PC00235;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0003607|UniProtKB=P05205 P05205 Su(var)205 PTHR22812:SF112 CHROMOBOX PROTEIN CHROMATOR, ISOFORM A-RELATED chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828 chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome#GO:0005694;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0033209|UniProtKB=Q7JXE4 Q7JXE4 Dmel\CG12107 PTHR12906:SF0 PROTEIN C20ORF24 RAB5-INTERACTING PROTEIN GEL COMPLEX SUBUNIT OPTI DROME|FlyBase=FBgn0263355|UniProtKB=Q9VIM1 Q9VIM1 CG11017 PTHR30615:SF8 UNCHARACTERIZED PROTEIN YJBQ-RELATED UPF0047 PROTEIN C4A8.02C DROME|FlyBase=FBgn0039609|UniProtKB=Q9VAS4 Q9VAS4 Nepl17 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0266347|UniProtKB=A0A0S0WNY8 A0A0S0WNY8 nAChRalpha4 PTHR18945:SF928 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA4, ISOFORM H monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 DROME|FlyBase=FBgn0053002|UniProtKB=Q86BM8 Q86BM8 mRpL27 PTHR15893:SF17 RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 DROME|FlyBase=FBgn0034759|UniProtKB=Q9W220 Q9W220 Dmel\CG13511 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035924|UniProtKB=Q9VSP8 Q9VSP8 Dmel\CG6576 PTHR23326:SF35 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;CCR4-NOT complex#GO:0030014;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;P-body#GO:0000932;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039581|UniProtKB=Q9VAW1 Q9VAW1 Moca-cyp PTHR11071:SF565 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYLPROLYL ISOMERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 DROME|FlyBase=FBgn0037981|UniProtKB=Q9VGE2 Q9VGE2 Spt3 PTHR11380:SF16 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 general transcription factor#PC00259 DROME|FlyBase=FBgn0024365|UniProtKB=O46100 O46100 EG:8D8.3 PTHR11827:SF6 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 8 chloride transmembrane transporter activity#GO:0015108;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034402|UniProtKB=Q7K0F0 Q7K0F0 CG15084 PTHR12111:SF2 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2B-RELATED ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0031150|UniProtKB=Q9VRE2 Q9VRE2 bves PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;developmental process#GO:0032502;muscle structure development#GO:0061061;cell differentiation#GO:0030154;circulatory system development#GO:0072359;muscle cell differentiation#GO:0042692;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;sarcolemma#GO:0042383 DROME|FlyBase=FBgn0283450|UniProtKB=A1Z6X6 A1Z6X6 Glo1 PTHR10374:SF30 LACTOYLGLUTATHIONE LYASE GLYOXALASE I LACTOYLGLUTATHIONE LYASE lyase#PC00144;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039900|UniProtKB=Q9V4C4 Q9V4C4 Syt7 PTHR10024:SF344 SYNAPTOTAGMIN SYNAPTOTAGMIN 7, ISOFORM A phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772 regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;localization#GO:0051179;vesicle fusion#GO:0006906;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;vesicle organization#GO:0016050;regulation of transport#GO:0051049;regulation of localization#GO:0032879;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0035904|UniProtKB=Q9VSL2 Q9VSL2 GstO3 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;transferase activity#GO:0016740;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0030311|UniProtKB=Q9VYX5 Q9VYX5 Dmel\CG11699 PTHR13141:SF4 TRANSMEMBRANE PROTEIN 242 TRANSMEMBRANE PROTEIN 242 DROME|FlyBase=FBgn0039415|UniProtKB=Q9VBG8 Q9VBG8 Dmel\CG6142 PTHR11552:SF216 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034822|UniProtKB=Q9W1U6 Q9W1U6 RpL37-2 PTHR10768:SF0 60S RIBOSOMAL PROTEIN L37 RIBOSOMAL PROTEIN L37 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 DROME|FlyBase=FBgn0033680|UniProtKB=Q7JWU2 Q7JWU2 Dmel\CG13186 PTHR33638:SF1 SELENOPROTEIN H SELENOPROTEIN H organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0052333|UniProtKB=M9PGQ5 M9PGQ5 CG9137 PTHR12482:SF5 LIPASE ROG1-RELATED-RELATED DUF676 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 DROME|FlyBase=FBgn0027552|UniProtKB=Q9Y112 Q9Y112 Ar3 PTHR11732:SF385 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0032482|UniProtKB=Q9VK25 Q9VK25 Pect PTHR45780:SF2 ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174;transferase#PC00220 DROME|FlyBase=FBgn0027929|UniProtKB=M9PFV3 M9PFV3 NimB1 PTHR24047:SF32 FI01909P-RELATED FI01909P-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0027535|UniProtKB=Q9XZ08 Q9XZ08 botv PTHR11062:SF73 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 3 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0035853|UniProtKB=Q9VSF3 Q9VSF3 UbcE2M PTHR24068:SF132 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBCE2M catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0041250|UniProtKB=Q9VPT1 Q9VPT1 Gr21a PTHR21143:SF139 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 21A molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;neuron projection#GO:0043005;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0023506|UniProtKB=O44424 O44424 Es2 PTHR12940:SF0 ES-2 PROTEIN - RELATED SPLICING FACTOR ESS-2 HOMOLOG ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0000592|UniProtKB=P08171 P08171 Est-6 PTHR11559:SF429 CARBOXYLESTERASE ESTERASE P-RELATED esterase#PC00097 DROME|FlyBase=FBgn0030806|UniProtKB=Q9VX94 Q9VX94 Dmel\CG13001 PTHR31058:SF2 ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of neuron differentiation#GO:0045664;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;multicellular organism development#GO:0007275;positive regulation of cell differentiation#GO:0045597;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0026619|UniProtKB=Q9V6G5 Q9V6G5 Taz PTHR12497:SF8 TAZ PROTEIN TAFAZZIN TAFAZZIN transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular component organization or biogenesis#GO:0071840;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;glycerophospholipid metabolic process#GO:0006650;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 acyltransferase#PC00042 DROME|FlyBase=FBgn0051495|UniProtKB=Q8ING5 Q8ING5 Dmel\CG31495 PTHR23078:SF3 VESICULAR-FUSION PROTEIN NSF VESICLE-FUSING ATPASE hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 vesicle-mediated transport#GO:0016192;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to cell periphery#GO:1990778;transport#GO:0006810;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;intra-Golgi vesicle-mediated transport#GO:0006891;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668 Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>NSF#P05774;Ionotropic glutamate receptor pathway#P00037>NSF#P01020 DROME|FlyBase=FBgn0030009|UniProtKB=R4GRV8 R4GRV8 Dmel\CG15336 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0004913|UniProtKB=P35600 P35600 Gnf1 PTHR23389:SF6 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 REPLICATION FACTOR C SUBUNIT 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0050286|UniProtKB=Q8MLV9 Q8MLV9 SP37 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0039835|UniProtKB=Q9V9Z1 Q9V9Z1 mRpL32 PTHR21026:SF2 39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 DROME|FlyBase=FBgn0034047|UniProtKB=A1ZA55 A1ZA55 cGlr1 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED transferase#PC00220;nucleotidyltransferase#PC00174 DROME|FlyBase=FBgn0033773|UniProtKB=Q1EC11 Q1EC11 Mos PTHR23257:SF994 SERINE-THREONINE PROTEIN KINASE IP11267P catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0053969|UniProtKB=Q8SX44 Q8SX44 CG32429 PTHR14381:SF1 DACTYLIN F-BOX_WD REPEAT-CONTAINING PROTEIN 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;response to stimulus#GO:0050896;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;response to stress#GO:0006950 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 DROME|FlyBase=FBgn0266411|UniProtKB=Q24167 Q24167 sima PTHR23043:SF17 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PROTEIN SIMILAR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;regulation of biosynthetic process#GO:0009889;response to hypoxia#GO:0001666;intracellular chemical homeostasis#GO:0055082;regulation of gene expression#GO:0010468;cellular homeostasis#GO:0019725;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0029974|UniProtKB=Q9W3N2 Q9W3N2 dpr14 PTHR23279:SF3 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 14, ISOFORM A-RELATED cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 DROME|FlyBase=FBgn0037885|UniProtKB=A0A0B4K658 A0A0B4K658 BcDNA:LP09251 PTHR45969:SF69 RING ZINC FINGER PROTEIN-RELATED RING-TYPE DOMAIN-CONTAINING PROTEIN ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 DROME|FlyBase=FBgn0033710|UniProtKB=Q7K3Y9 Q7K3Y9 Dmel\CG17739 PTHR11311:SF16 SPONDIN SPONDIN-1 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0034605|UniProtKB=Q9W2J3 Q9W2J3 Ugt49C1 PTHR48043:SF60 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 DROME|FlyBase=FBgn0035830|UniProtKB=Q9VSC5 Q9VSC5 anon-WO0172774.138 PTHR46340:SF1 UBX DOMAIN-CONTAINING PROTEIN 1 UBX DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;negative regulation of protein ubiquitination#GO:0031397;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of post-translational protein modification#GO:1901873;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;regulation of protein ubiquitination#GO:0031396;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;regulation of catabolic process#GO:0009894;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0027865|UniProtKB=A0A0B4KH03 A0A0B4KH03 Tsp96F PTHR19282:SF551 TETRASPANIN TETRASPANIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0266429|UniProtKB=Q9U721 Q9U721 AstA-R1 PTHR24229:SF103 NEUROPEPTIDES RECEPTOR ALLATOSTATIN A RECEPTOR 1, ISOFORM B G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;neuropeptide binding#GO:0042923;peptide binding#GO:0042277 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0010044|UniProtKB=Q9VG92 Q9VG92 GstD8 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0025109|UniProtKB=O76462 O76462 Bem46 PTHR12277:SF207 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD13 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203 DROME|FlyBase=FBgn0038948|UniProtKB=Q9VD28 Q9VD28 JMJD6 PTHR12480:SF32 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6 localization#GO:0051179;establishment of localization#GO:0051234;endocytosis#GO:0006897;import into cell#GO:0098657;phagocytosis#GO:0006909;transport#GO:0006810 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0283666|UniProtKB=O96692 O96692 Rap2l PTHR24070:SF462 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cell communication#GO:0007154;regulation of cell motility#GO:2000145;intracellular signal transduction#GO:0035556;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cell migration#GO:0030334;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;small GTPase-mediated signal transduction#GO:0007264;negative regulation of locomotion#GO:0040013 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 DROME|FlyBase=FBgn0283434|UniProtKB=T2FGB0 T2FGB0 SdicC PTHR12442:SF22 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;microtubule-based transport#GO:0099111;intracellular transport#GO:0046907 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0031974|UniProtKB=Q9VLU3 Q9VLU3 Dmel\CG12560 PTHR20958:SF10 GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN GH05617P-RELATED DROME|FlyBase=FBgn0032669|UniProtKB=Q9VJ99 Q9VJ99 Dmel\CG15155 PTHR20958:SF10 GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN GH05617P-RELATED DROME|FlyBase=FBgn0052409|UniProtKB=Q8I937 Q8I937 BcDNA:LD24586 PTHR17602:SF4 RIBOSOME BIOGENESIS REGULATORY PROTEIN RIBOSOME BIOGENESIS REGULATORY PROTEIN HOMOLOG RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0030262|UniProtKB=Q9VZ35 Q9VZ35 Vago PTHR39957:SF1 AT09846P1-RELATED AT09846P1-RELATED DROME|FlyBase=FBgn0020369|UniProtKB=O18413 O18413 Rpt6 PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0035091|UniProtKB=Q961K6 Q961K6 bez PTHR11923:SF50 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 GH19047P cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0028515|UniProtKB=Q9V3V9 Q9V3V9 EndoGI PTHR12604:SF2 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU70 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;double-strand break repair via nonhomologous end joining#GO:0006303;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;telomere maintenance#GO:0000723 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA helicase#PC00011 DROME|FlyBase=FBgn0038876|UniProtKB=Q9VDC2 Q9VDC2 Idi PTHR10885:SF24 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 isomerase#PC00135 DROME|FlyBase=FBgn0037064|UniProtKB=Q9VP62 Q9VP62 Dmel\CG9389 PTHR20854:SF4 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cell communication#GO:0007154;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biological regulation#GO:0065007;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 DROME|FlyBase=FBgn0035640|UniProtKB=Q9VRQ2 Q9VRQ2 mad2 PTHR11842:SF11 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of chromosome organization#GO:2001251;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of mitotic metaphase/anaphase transition#GO:0030071;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;negative regulation of cell cycle#GO:0045786;negative regulation of chromosome segregation#GO:0051985;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 DROME|FlyBase=FBgn0037005|UniProtKB=Q9VPD8 Q9VPD8 Dmel\CG5078 PTHR23504:SF1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 GH21943P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0004456|UniProtKB=Q24247 Q24247 mew PTHR23220:SF122 INTEGRIN ALPHA INTEGRIN ALPHA-PS1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 DROME|FlyBase=FBgn0031375|UniProtKB=Q9VQ56 Q9VQ56 erm PTHR24393:SF135 ZINC FINGER PROTEIN FEZ FAMILY ZINC FINGER PROTEIN ERM transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0036996|UniProtKB=Q9VPE9 Q9VPE9 mag PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0016684|UniProtKB=Q7JZR4 Q7JZR4 NaPi-T PTHR11662:SF79 SOLUTE CARRIER FAMILY 17 NA[+]-DEPENDENT INORGANIC PHOSPHATE COTRANSPORTER, ISOFORM A transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0030858|UniProtKB=Q9VX31 Q9VX31 IntS2 PTHR28608:SF1 INTEGRATOR COMPLEX SUBUNIT 2 INTEGRATOR COMPLEX SUBUNIT 2 transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;catabolic process#GO:0009056;snRNA 3'-end processing#GO:0034472;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0053128|UniProtKB=Q9VQ12 Q9VQ12 CG10872 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;primary metabolic process#GO:0044238;programmed cell death#GO:0012501 protease#PC00190;aspartic protease#PC00053 DROME|FlyBase=FBgn0031905|UniProtKB=Q9VM21 Q9VM21 gudu PTHR46241:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 4 ARMC4 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 2 DROME|FlyBase=FBgn0266438|UniProtKB=Q8MT80 Q8MT80 PIG-Z PTHR22760:SF3 GLYCOSYLTRANSFERASE GPI ALPHA-1,2-MANNOSYLTRANSFERASE 4 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0051296|UniProtKB=Q8IND6 Q8IND6 NEST:bs01d08 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0024188|UniProtKB=Q9NHD5 Q9NHD5 san PTHR42919:SF8 N-ALPHA-ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 50 acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitotic sister chromatid cohesion#GO:0007064 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transferase#PC00220;acetyltransferase#PC00038 DROME|FlyBase=FBgn0043884|UniProtKB=Q9VCA8 Q9VCA8 mask PTHR23206:SF8 MASK PROTEIN ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0032149|UniProtKB=Q9VL81 Q9VL81 Dmel\CG4036 PTHR12463:SF0 OXYGENASE-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;contractile ring#GO:0070938;midbody#GO:0030496 oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0004901|UniProtKB=Q27601 Q27601 Prat PTHR11907:SF0 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740 organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;transferase#PC00220 De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 DROME|FlyBase=FBgn0004118|UniProtKB=P25162 P25162 nAChRbeta2 PTHR18945:SF927 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-LIKE 2 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 DROME|FlyBase=FBgn0035517|UniProtKB=Q9VZF3 Q9VZF3 Dmel\CG1265 PTHR12226:SF3 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED SOLUTE CARRIER FAMILY 66 MEMBER 3 DROME|FlyBase=FBgn0085200|UniProtKB=A8DZ15 A8DZ15 Dmel\CG34171 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0283659|UniProtKB=Q9V3N8 Q9V3N8 Thg PTHR12729:SF6 TRNA(HIS) GUANYLYLTRANSFERASE-RELATED TRNA(HIS) GUANYLYLTRANSFERASE-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 DROME|FlyBase=FBgn0016794|UniProtKB=Q9VZZ9 Q9VZZ9 dos PTHR45960:SF2 GRB2-ASSOCIATED-BINDING PROTEIN PROTEIN DAUGHTER OF SEVENLESS scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Gab#P00563 DROME|FlyBase=FBgn0036652|UniProtKB=Q9VV90 Q9VV90 Ccdc13 PTHR31935:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 microtubule cytoskeleton organization#GO:0000226;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cytoplasmic microtubule organization#GO:0031122;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 DROME|FlyBase=FBgn0038473|UniProtKB=Q8MT06 Q8MT06 Ns1 PTHR11089:SF30 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0032486|UniProtKB=Q9VK20 Q9VK20 mRF1 PTHR43804:SF7 LD18447P LD18447P translational protein#PC00263;translation factor#PC00223;translation release factor#PC00225 DROME|FlyBase=FBgn0037908|UniProtKB=Q961T8 Q961T8 dpr5 PTHR23279:SF41 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 4-RELATED cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256 DROME|FlyBase=FBgn0259215|UniProtKB=Q9VDH6 Q9VDH6 Ir93a PTHR18966:SF594 IONOTROPIC GLUTAMATE RECEPTOR IONOTROPIC RECEPTOR 93A glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0027506|UniProtKB=A1ZAS8 A1ZAS8 EDTP PTHR13524:SF2 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR14 phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0037000|UniProtKB=Q9VPE3 Q9VPE3 ZnT77C PTHR45820:SF9 FI23527P1 FI23527P1 monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385 detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;response to chemical#GO:0042221;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;detoxification#GO:0098754;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;response to metal ion#GO:0010038;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;metal ion transport#GO:0030001;homeostatic process#GO:0042592;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0083228|UniProtKB=Q9VWX8 Q9VWX8 Frq2 PTHR23055:SF198 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 1 enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851;molecular function regulator activity#GO:0098772;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;cation binding#GO:0043169;molecular function activator activity#GO:0140677 calmodulin-related#PC00061 DROME|FlyBase=FBgn0033297|UniProtKB=A1Z7F3 A1Z7F3 Mal-A8 PTHR10357:SF234 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A2-RELATED primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311 metabolite interconversion enzyme#PC00262;amylase#PC00048 DROME|FlyBase=FBgn0026415|UniProtKB=Q9W303 Q9W303 Idgf4 PTHR11177:SF235 CHITINASE CHITINASE-LIKE PROTEIN IDGF1-RELATED catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 DROME|FlyBase=FBgn0039324|UniProtKB=Q9VBS4 Q9VBS4 CT29612 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0031089|UniProtKB=Q9W5X1 Q9W5X1 aspr PTHR22963:SF38 ENDOGLIN-RELATED ASPEROUS, ISOFORM A DROME|FlyBase=FBgn0053547|UniProtKB=A0A0B4K6M2 A0A0B4K6M2 Rim PTHR12157:SF21 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN RAB3 INTERACTING MOLECULE, ISOFORM F structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;signaling#GO:0023052;export from cell#GO:0140352;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular localization#GO:0051641;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;neurotransmitter transport#GO:0006836;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulation of transport#GO:0051049;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytic process#GO:0140029;regulated exocytosis#GO:0045055 presynaptic active zone#GO:0048786;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;synaptic membrane#GO:0097060;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;cell cortex#GO:0005938 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0039641|UniProtKB=Q9VAN9 Q9VAN9 Dmel\CG14511 PTHR10778:SF4 SOLUTE CARRIER FAMILY 35 MEMBER B NUCLEOTIDE SUGAR TRANSPORTER SLC35B4 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0030317|UniProtKB=Q7KV34 Q7KV34 pkm PTHR11012:SF30 PROTEIN KINASE-LIKE DOMAIN-CONTAINING PROTEIN KINASE-LIKE DOMAIN-CONTAINING DROME|FlyBase=FBgn0029167|UniProtKB=Q9VU94 Q9VU94 Hml PTHR11339:SF416 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED HEMOLECTIN, ISOFORM A structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0260780|UniProtKB=Q9VYS4 Q9VYS4 wisp PTHR12271:SF140 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE GLD2 catalytic activity, acting on RNA#GO:0140098;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA destabilization#GO:0061157;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 nucleotidyltransferase#PC00174 DROME|FlyBase=FBgn0027903|UniProtKB=Q9W088 Q9W088 PolD2 PTHR10416:SF0 DNA POLYMERASE DELTA SUBUNIT 2 DNA POLYMERASE DELTA SUBUNIT 2 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;DNA-templated DNA replication#GO:0006261 DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;replication fork#GO:0005657;replisome#GO:0030894;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 DROME|FlyBase=FBgn0036188|UniProtKB=Q9VTL6 Q9VTL6 Polr3H PTHR12709:SF1 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0025608|UniProtKB=Q9VJ58 Q9VJ58 Faf2 PTHR23322:SF1 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 2 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0003886|UniProtKB=P06604 P06604 alphaTub85E PTHR11588:SF239 TUBULIN TUBULIN ALPHA CHAIN ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 tubulin#PC00228;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0032827|UniProtKB=Q7KT29 Q7KT29 Dmel\CG10481 PTHR10783:SF127 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED LD30826P-RELATED secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;efflux transmembrane transporter activity#GO:0015562;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;homeostatic process#GO:0042592;export from cell#GO:0140352;phosphate ion transport#GO:0006817;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0039582|UniProtKB=Q9VAW0 Q9VAW0 Or98b PTHR21137:SF43 ODORANT RECEPTOR ODORANT RECEPTOR 47A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0002930|UniProtKB=Q7JWX3 Q7JWX3 nec PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0037518|UniProtKB=Q9VI00 Q9VI00 Dmel\CG2641 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0029795|UniProtKB=Q9W487 Q9W487 Dmel\CG15773 PTHR21721:SF27 GH09876P-RELATED GH09876P DROME|FlyBase=FBgn0034428|UniProtKB=A1ZBI8 A1ZBI8 AANATL6 PTHR20905:SF33 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 transferase#PC00220;acetyltransferase#PC00038 DROME|FlyBase=FBgn0086472|UniProtKB=P48588 P48588 RpS25 PTHR12850:SF5 40S RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN ES25 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 DROME|FlyBase=FBgn0035957|UniProtKB=Q9VST4 Q9VST4 Argk2 PTHR11547:SF38 ARGININE OR CREATINE KINASE ARGININE KINASE 1-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0004648|UniProtKB=P42787 P42787 svr PTHR11532:SF73 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 DROME|FlyBase=FBgn0262534|UniProtKB=M9NGE9 M9NGE9 MB8.chrX.pasa.104-MIP02663 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0030778|UniProtKB=B7Z0Z5 B7Z0Z5 Dmel\CG4678 PTHR11532:SF96 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE PROTEIN peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metallopeptidase activity#GO:0008237 peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 DROME|FlyBase=FBgn0020645|UniProtKB=P91940 P91940 Lcp65Aa PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0025678|UniProtKB=Q9V438 Q9V438 CaBP1 PTHR45815:SF3 PROTEIN DISULFIDE-ISOMERASE A6 PROTEIN DISULFIDE-ISOMERASE A6 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 DROME|FlyBase=FBgn0002778|UniProtKB=Q9Y1A7 Q9Y1A7 mnd PTHR11785:SF528 AMINO ACID TRANSPORTER LD25378P L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0015924|UniProtKB=Q27367 Q27367 crq PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI02050P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0053764|UniProtKB=Q2MGL5 Q2MGL5 Dmel\CG33764 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0028480|UniProtKB=Q9V3S7 Q9V3S7 Dmel\CG17841 PTHR13439:SF66 CT120 PROTEIN BCDNA.GH12326 homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;lipid homeostasis#GO:0055088 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0050280|UniProtKB=Q4V4U2 Q4V4U2 AAF46801 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0031275|UniProtKB=Q9VPS7 Q9VPS7 GABA-B-R3 PTHR10519:SF46 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;signaling receptor complex#GO:0043235 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0033321|UniProtKB=A1Z7H8 A1Z7H8 Dmel\CG8738 PTHR24256:SF555 TRYPTASE-RELATED PHENOLOXIDASE-ACTIVATING FACTOR 2 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0029747|UniProtKB=Q9W4E4 Q9W4E4 Dmel\CG5062 PTHR15504:SF0 NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45 regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;regulation of biological quality#GO:0065008;regulation of microtubule-based process#GO:0032886 supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929 DROME|FlyBase=FBgn0039160|UniProtKB=Q9VCC2 Q9VCC2 Dmel\CG5510 PTHR12223:SF45 VESICULAR MANNOSE-BINDING LECTIN RE50040P carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029;small molecule binding#GO:0036094;binding#GO:0005488 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0083167|UniProtKB=Q9W2U8 Q9W2U8 Neb-cGP PTHR34038:SF1 ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT K, MITOCHONDRIAL catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991 ATP synthase#PC00002 DROME|FlyBase=FBgn0032783|UniProtKB=Q9VIW5 Q9VIW5 Dmel\CG10237 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0040384|UniProtKB=Q9U1M2 Q9U1M2 CG32795 PTHR21433:SF0 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120 HOMOLOG intracellular organelle#GO:0043229;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0026314|UniProtKB=Q9VGT0 Q9VGT0 Ugt35B1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0051703|UniProtKB=Q8IME7 Q8IME7 tplus3b PTHR13115:SF8 RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0029821|UniProtKB=Q9W459 Q9W459 Dmel\CG4020 PTHR11011:SF24 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0032612|UniProtKB=Q9VJH1 Q9VJH1 Dmel\CG13282 PTHR11610:SF151 LIPASE PHOSPHOLIPASE A1 MEMBER A-LIKE PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0031184|UniProtKB=Q9VR51 Q9VR51 Dmel\CG14615 PTHR20958:SF10 GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN GH05617P-RELATED DROME|FlyBase=FBgn0263738|UniProtKB=Q7KSD8 Q7KSD8 Ada2a PTHR12374:SF85 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-ALPHA transcription coactivator activity#GO:0003713;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coregulator activity#GO:0003712 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0052271|UniProtKB=Q8IRE2 Q8IRE2 Dmel\CG32271 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036104|UniProtKB=Q9VTC1 Q9VTC1 DmRH27 PTHR24031:SF125 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX42 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0053796|UniProtKB=Q4ABJ5 Q4ABJ5 Dmel\CG33796 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0031650|UniProtKB=Q9VMY2 Q9VMY2 synr PTHR21974:SF2 RE15880P RE15880P cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 DROME|FlyBase=FBgn0034491|UniProtKB=Q7JR83 Q7JR83 Hsl PTHR23025:SF3 TRIACYLGLYCEROL LIPASE HORMONE-SENSITIVE LIPASE triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;neutral lipid catabolic process#GO:0046461;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;triglyceride catabolic process#GO:0019433;acylglycerol metabolic process#GO:0006639;glycerolipid catabolic process#GO:0046503;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 DROME|FlyBase=FBgn0038731|UniProtKB=Q9VDU3 Q9VDU3 Acsx1R PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 ligase#PC00142 DROME|FlyBase=FBgn0038934|UniProtKB=Q9VD44 Q9VD44 Gld2 PTHR12271:SF140 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE GLD2 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity, acting on RNA#GO:0140098 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;RNA processing#GO:0006396;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;mRNA processing#GO:0006397;RNA destabilization#GO:0050779;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 nucleotidyltransferase#PC00174 DROME|FlyBase=FBgn0031310|UniProtKB=Q9VPX5 Q9VPX5 Vps29 PTHR11124:SF12 VACUOLAR SORTING PROTEIN VPS29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;retromer complex#GO:0030904;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0031420|UniProtKB=Q9VQB6 Q9VQB6 Atxn7 PTHR31534:SF3 ATAXIN 7, ISOFORM A ATAXIN-7 DROME|FlyBase=FBgn0288686|UniProtKB=P08841 P08841 betaTub60D PTHR11588:SF273 TUBULIN TUBULIN BETA-3 CHAIN guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 DROME|FlyBase=FBgn0050389|UniProtKB=A0A0B4KEW2 A0A0B4KEW2 Dmel\CG30389 PTHR13289:SF6 PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL MACOILIN tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cell communication#GO:0007154;response to external stimulus#GO:0009605;chemotaxis#GO:0006935;response to chemical#GO:0042221;taxis#GO:0042330;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;locomotion#GO:0040011;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 nuclear membrane#GO:0031965;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane#GO:0016020;nucleus#GO:0005634;rough endoplasmic reticulum#GO:0005791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967 transporter#PC00227 DROME|FlyBase=FBgn0028894|UniProtKB=Q9VJL6 Q9VJL6 GMF PTHR11249:SF2 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR protein-containing complex binding#GO:0044877;binding#GO:0005488 negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0031860|UniProtKB=Q9VM80 Q9VM80 Daao2 PTHR11530:SF11 D-AMINO ACID OXIDASE D-AMINO ACID OXIDASE 2, ISOFORM A catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidase#PC00175 DROME|FlyBase=FBgn0003334|UniProtKB=Q9VHA0 Q9VHA0 Scm PTHR12247:SF132 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SCM histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0034142|UniProtKB=Q960W6 Q960W6 CG8306 PTHR11011:SF126 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE CG8306-RELATED oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031802|UniProtKB=Q9VME9 Q9VME9 ppk7 PTHR11690:SF288 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0036839|UniProtKB=Q9VVV8 Q9VVV8 SmydA-2 PTHR46455:SF5 SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 2 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0033672|UniProtKB=A1Z8R8 A1Z8R8 rho-7 PTHR43731:SF14 RHOMBOID PROTEASE PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 serine protease#PC00203 DROME|FlyBase=FBgn0033656|UniProtKB=Q7JZ56 Q7JZ56 S2P PTHR13325:SF3 PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;membrane protein proteolysis#GO:0033619;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;regulation of cellular response to stress#GO:0080135;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;proteolysis#GO:0006508;regulation of response to stimulus#GO:0048583 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 DROME|FlyBase=FBgn0023524|UniProtKB=A0A4D6K3U9 A0A4D6K3U9 EG:30B8.6 PTHR19444:SF11 UNC-93 RELATED UNC93-LIKE PROTEIN molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108 regulation of muscle contraction#GO:0006937;regulation of system process#GO:0044057;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of multicellular organismal process#GO:0051239;homeostatic process#GO:0042592;biological regulation#GO:0065007 organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;contractile muscle fiber#GO:0043292;cell periphery#GO:0071944;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 membrane-bound signaling molecule#PC00152 DROME|FlyBase=FBgn0262867|UniProtKB=Q86P36 Q86P36 Ptr PTHR10796:SF194 PATCHED-RELATED PATCHED-RELATED, ISOFORM A cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle membrane#GO:0031090 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0083956|UniProtKB=X2JG15 X2JG15 ldd PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0283478|UniProtKB=Q9VL89 Q9VL89 und PTHR45777:SF2 METHIONINE AMINOPEPTIDASE 2 METHIONINE AMINOPEPTIDASE 2 metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0046222|UniProtKB=Q9VNG2 Q9VNG2 Wdr33 PTHR22836:SF0 WD40 REPEAT PROTEIN PRE-MRNA 3' END PROCESSING PROTEIN WDR33 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030588|UniProtKB=Q9VY10 Q9VY10 Dmel\CG9521 PTHR11552:SF158 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE GH23626P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0004777|UniProtKB=O97064 O97064 Ccp84Ag PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0262737|UniProtKB=M9NEH9 M9NEH9 mub PTHR10288:SF347 KH DOMAIN CONTAINING RNA BINDING PROTEIN MUSHROOM-BODY EXPRESSED, ISOFORM K RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031078|UniProtKB=Q8IQV9 Q8IQV9 Nup205 PTHR31344:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP205 NUCLEAR PORE COMPLEX PROTEIN NUP205 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 protein-containing complex organization#GO:0043933;nuclear pore organization#GO:0006999;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967 DROME|FlyBase=FBgn0000447|UniProtKB=P32748 P32748 Dhod PTHR48109:SF4 DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydrooratate oxidase#P02927 DROME|FlyBase=FBgn0031344|UniProtKB=M9PAZ8 M9PAZ8 Dmel\CG7420 PTHR45982:SF8 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2-LIKE PROTEIN regulation of mitotic cell cycle#GO:0007346;regulation of organelle assembly#GO:1902115;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of mitotic spindle assembly#GO:1901673;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of microtubule-based process#GO:0032886;regulation of spindle assembly#GO:0090169;regulation of mitotic spindle organization#GO:0060236 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0000114|UniProtKB=Q8IP90 Q8IP90 bru1 PTHR24012:SF877 RNA BINDING PROTEIN BRUNO 1, ISOFORM B-RELATED RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;regulation of RNA metabolic process#GO:0051252;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030683|UniProtKB=Q9VXQ3 Q9VXQ3 Mvd PTHR10977:SF3 DIPHOSPHOMEVALONATE DECARBOXYLASE DIPHOSPHOMEVALONATE DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;isoprenoid biosynthetic process#GO:0008299;acetyl-CoA metabolic process#GO:0006084;phospholipid metabolic process#GO:0006644;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;phospholipid biosynthetic process#GO:0008654;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 lyase#PC00144;decarboxylase#PC00089 Cholesterol biosynthesis#P00014>Diphosphomevalonate decarboxylase#P00496 DROME|FlyBase=FBgn0039235|UniProtKB=Q8IMV4 Q8IMV4 CAH4 PTHR18952:SF137 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0032730|UniProtKB=Q9VJ27 Q9VJ27 Dmel\CG10431 PTHR24406:SF23 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0051205|UniProtKB=Q8IN51 Q8IN51 Dmel\CG31205 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0041097|UniProtKB=Q9VPZ7 Q9VPZ7 robo3 PTHR13817:SF183 TITIN LP22668P anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869 structural protein#PC00211 Axon guidance mediated by Slit/Robo#P00008>Robo#P00348 DROME|FlyBase=FBgn0051086|UniProtKB=Q9VBG7 Q9VBG7 Dmel\CG31086 PTHR31649:SF10 AGAP009604-PA IP19903P-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0265597|UniProtKB=X2JDH0 X2JDH0 rsh PTHR15711:SF25 RAP GTPASE-ACTIVATING PROTEIN RADISH, ISOFORM I GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022 DROME|FlyBase=FBgn0053196|UniProtKB=M9PB30 M9PB30 dpy PTHR22963:SF39 ENDOGLIN-RELATED DUMPY, ISOFORM Q DROME|FlyBase=FBgn0031805|UniProtKB=Q9VME6 Q9VME6 Nepl4 PTHR11733:SF252 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-LIKE 4 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0287695|UniProtKB=Q9VMC9 Q9VMC9 KFase PTHR48081:SF36 AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C KYNURENINE FORMAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 hydrolase#PC00121 DROME|FlyBase=FBgn0029501|UniProtKB=Q9W164 Q9W164 Crtp PTHR39944:SF1 FAMILY NOT NAMED CALDESMON-RELATED PROTEIN-RELATED DROME|FlyBase=FBgn0034957|UniProtKB=Q9W1D3 Q9W1D3 Rsph4a PTHR13159:SF0 RADIAL SPOKEHEAD-RELATED RADIAL SPOKE HEAD COMPONENT 4A cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;organelle assembly#GO:0070925;cilium movement#GO:0003341;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;axoneme#GO:0005930 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0004427|UniProtKB=P83972 P83972 LysD PTHR11407:SF63 LYSOZYME C LYSOZYME lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824 glycosidase#PC00110 DROME|FlyBase=FBgn0033808|UniProtKB=Q059A4 Q059A4 Tmem186 PTHR13603:SF1 TRANSMEMBRANE PROTEIN 186 TRANSMEMBRANE PROTEIN 186 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0038760|UniProtKB=Q9VDR1 Q9VDR1 MED25 PTHR12433:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0015905|UniProtKB=Q9VPW1 Q9VPW1 ast PTHR15665:SF1 ASTEROID PROTEIN SINGLE-STRAND DNA ENDONUCLEASE ASTE1 DROME|FlyBase=FBgn0259716|UniProtKB=Q9VME2 Q9VME2 Nepl6 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0033638|UniProtKB=Q7JXG9 Q7JXG9 atos PTHR13199:SF11 GH03947P PROTEIN ATOSSA DROME|FlyBase=FBgn0034681|UniProtKB=Q9W2A6 Q9W2A6 Dmel\CG9308 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 vesicle coat protein#PC00235;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0037979|UniProtKB=Q9VGE4 Q9VGE4 GCC185 PTHR18902:SF32 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED FI04457P-RELATED microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0085370|UniProtKB=Q9VJ79 Q9VJ79 Pde11 PTHR11347:SF20 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 hydrolase#PC00121;phosphodiesterase#PC00185 DROME|FlyBase=FBgn0023129|UniProtKB=Q9VSY6 Q9VSY6 aay PTHR43344:SF2 PHOSPHOSERINE PHOSPHATASE PHOSPHOSERINE PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;magnesium ion binding#GO:0000287;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Phosphoserine phosphatase#P03159 DROME|FlyBase=FBgn0031321|UniProtKB=Q9VPY8 Q9VPY8 Tgt PTHR43530:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0010113|UniProtKB=Q9N2M8 Q9N2M8 heca PTHR13425:SF3 HEADCASE PROTEIN HEADCASE PROTEIN HOMOLOG DROME|FlyBase=FBgn0037060|UniProtKB=M9PFU5 M9PFU5 Dmel\CG10508 PTHR14791:SF23 BOMB/KIRA PROTEINS SUBFAMILY NOT NAMED protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of response to stimulus#GO:0048583;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of macromolecule metabolic process#GO:0060255;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0036936|UniProtKB=Q9VW77 Q9VW77 CT33794 PTHR22708:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 DROME|FlyBase=FBgn0035106|UniProtKB=Q7YZH1 Q7YZH1 rno PTHR13793:SF160 PHD FINGER PROTEINS PHD FINGER PROTEIN RHINOCEROS histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0037433|UniProtKB=Q9VI09 Q9VI09 Dmel\CG17919 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 DROME|FlyBase=FBgn0033062|UniProtKB=Q9V9K7 Q9V9K7 Ars2 PTHR13165:SF0 ARSENITE-RESISTANCE PROTEIN 2 SERRATE RNA EFFECTOR MOLECULE HOMOLOG RNA binding#GO:0003723;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;primary miRNA processing#GO:0031053;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0038753|UniProtKB=Q9VDR9 Q9VDR9 Dmel\CG4459 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0031146|UniProtKB=Q9VRD7 Q9VRD7 Dmel\CG15449 PTHR36692:SF2 PROTEIN SNAKESKIN GEO12064P1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0028573|UniProtKB=Q9VTR6 Q9VTR6 prc PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;circulatory system development#GO:0072359;heart development#GO:0007507;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036689|UniProtKB=Q9VVD3 Q9VVD3 Dmel\CG7730 PTHR21115:SF0 GH06117P-RELATED GH06117P-RELATED DROME|FlyBase=FBgn0263278|UniProtKB=Q8SWV6 Q8SWV6 Fic PTHR13504:SF34 FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145 PROTEIN ADENYLYLTRANSFERASE FICD catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 DROME|FlyBase=FBgn0038237|UniProtKB=Q9VFI9 Q9VFI9 Pde6 PTHR11347:SF216 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523 phosphodiesterase#PC00185;hydrolase#PC00121 DROME|FlyBase=FBgn0030793|UniProtKB=Q9VXA8 Q9VXA8 Rai1 PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0046113|UniProtKB=Q9VPV3 Q9VPV3 GluRIIC PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 DROME|FlyBase=FBgn0001098|UniProtKB=P54385 P54385 Gdh PTHR11606:SF13 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 DROME|FlyBase=FBgn0262477|UniProtKB=A0A0B4K6N2 A0A0B4K6N2 FoxP PTHR45796:SF4 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX P, ISOFORM C binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0021764|UniProtKB=O97394 O97394 sdk PTHR10075:SF14 BASIGIN RELATED PROTEIN SIDEKICK-1 ISOFORM X1 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0263239|UniProtKB=Q9VZN4 Q9VZN4 dar1 PTHR23235:SF183 KRUEPPEL-LIKE TRANSCRIPTION FACTOR DENDRITIC ARBOR REDUCTION PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0015035|UniProtKB=Q9VL92 Q9VL92 Cyp4e3 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034911|UniProtKB=Q9W1J0 Q9W1J0 GlyT PTHR11616:SF340 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;glycine transmembrane transporter activity#GO:0015187;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;amino acid transport#GO:0006865;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;monoatomic cation transport#GO:0006812 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 DROME|FlyBase=FBgn0050074|UniProtKB=A1Z9Q5 A1Z9Q5 Obp50d PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0031538|UniProtKB=Q9VQR0 Q9VQR0 Dmel\CG3246 PTHR11008:SF9 PROTEIN TAKEOUT-LIKE PROTEIN FI04421P DROME|FlyBase=FBgn0034546|UniProtKB=A1ZBY4 A1ZBY4 Dmel\CG13442 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039639|UniProtKB=Q9VAP1 Q9VAP1 Alg13 PTHR12867:SF6 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG13 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 transferase#PC00220 DROME|FlyBase=FBgn0265413|UniProtKB=Q9W398 Q9W398 CG7267 PTHR36692:SF2 PROTEIN SNAKESKIN GEO12064P1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0030000|UniProtKB=Q9W3K3 Q9W3K3 Dmel\CG2260 PTHR14085:SF3 WD-REPEAT PROTEIN BING4 WD REPEAT-CONTAINING PROTEIN 46 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040 DROME|FlyBase=FBgn0005613|UniProtKB=P40657 P40657 Sox15 PTHR10270:SF317 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-15-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0035152|UniProtKB=Q9W0P0 Q9W0P0 Dmel\CG3386 PTHR21505:SF8 MADF DOMAIN-CONTAINING PROTEIN-RELATED DPT-YFP REPRESSOR BY OVEREXPRESSION, ISOFORM D-RELATED DROME|FlyBase=FBgn0038617|UniProtKB=Q9VE73 Q9VE73 Wdr37 PTHR19855:SF12 WD40 REPEAT PROTEIN 12, 37 WD REPEAT-CONTAINING PROTEIN 37 DROME|FlyBase=FBgn0054031|UniProtKB=M9NDG6 M9NDG6 Dmel\CG34031 PTHR24333:SF9 HOMEO BOX HB9 LIKE A-RELATED HOMEOBOX DOMAIN-CONTAINING PROTEIN homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0030749|UniProtKB=Q9VXG4 Q9VXG4 AnxB11 PTHR10502:SF239 ANNEXIN ANNEXIN A7 ion binding#GO:0043167;phospholipid binding#GO:0005543;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 calcium-binding protein#PC00060 DROME|FlyBase=FBgn0036828|UniProtKB=Q9VVU6 Q9VVU6 Prp6 PTHR11246:SF1 PRE-MRNA SPLICING FACTOR PRE-MRNA-PROCESSING FACTOR 6 protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398 spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0039374|UniProtKB=Q9VBM0 Q9VBM0 Dmel\CG17770 PTHR23050:SF552 CALCIUM BINDING PROTEIN AT16150P-RELATED ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;cation binding#GO:0043169;molecular function regulator activity#GO:0098772 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061;calcium-binding protein#PC00060 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 DROME|FlyBase=FBgn0027107|UniProtKB=Q9VR82 Q9VR82 Inx6 PTHR11893:SF43 INNEXIN INNEXIN INX4-RELATED channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to radiation#GO:0009314;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 gap junction#PC00105 DROME|FlyBase=FBgn0052039|UniProtKB=Q8IQC6 Q8IQC6 Svip PTHR35269:SF1 SMALL VCP/P97-INTERACTING PROTEIN SMALL VCP_P97-INTERACTING PROTEIN regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;regulation of protein metabolic process#GO:0051246;positive regulation of autophagy#GO:0010508;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;regulation of protein localization#GO:0032880;regulation of cellular response to stress#GO:0080135;regulation of protein transport#GO:0051223;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of protein-containing complex assembly#GO:0043254;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein catabolic process#GO:0042176;regulation of establishment of protein localization#GO:0070201;negative regulation of catabolic process#GO:0009895;negative regulation of protein-containing complex assembly#GO:0031333;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transport#GO:0051051;negative regulation of protein metabolic process#GO:0051248;regulation of ERAD pathway#GO:1904292;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of cellular component organization#GO:0051129;regulation of response to endoplasmic reticulum stress#GO:1905897 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 DROME|FlyBase=FBgn0031195|UniProtKB=M9PJS6 M9PJS6 Dmel\CG17600 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 DROME|FlyBase=FBgn0036600|UniProtKB=Q9VV24 Q9VV24 BcDNA:RH10371 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0035142|UniProtKB=A0A6M3Q6U2 A0A6M3Q6U2 Hipk PTHR24058:SF135 DUAL SPECIFICITY PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036116|UniProtKB=Q9VTD7 Q9VTD7 Dmel\CG7888 PTHR22950:SF680 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 secondary carrier transporter#PC00258;amino acid transporter#PC00046 DROME|FlyBase=FBgn0040491|UniProtKB=Q8T8Y5 Q8T8Y5 Buffy PTHR11256:SF64 BCL-2 RELATED AT16536P channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;apoptotic signaling pathway#GO:0097190;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;signaling#GO:0023052;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0039297|UniProtKB=Q9VBV4 Q9VBV4 Jhbp7 PTHR11008:SF32 PROTEIN TAKEOUT-LIKE PROTEIN GH08336P-RELATED rhythmic process#GO:0048511;circadian rhythm#GO:0007623 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0051221|UniProtKB=A0A0B4KGY8 A0A0B4KGY8 CG11625 PTHR20967:SF0 PROHORMONE-4 PROHORMONE-4 DROME|FlyBase=FBgn0035734|UniProtKB=Q9VS11 Q9VS11 Dmel\CG14823 PTHR11195:SF13 DESTABILASE-RELATED LYSOZYME lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0261608|UniProtKB=Q9VMU4 Q9VMU4 RpL37A PTHR48129:SF1 60S RIBOSOMAL PROTEIN L37A LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 DROME|FlyBase=FBgn0030800|UniProtKB=Q9VXA0 Q9VXA0 Nprl2 PTHR12991:SF10 NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 GATOR1 COMPLEX PROTEIN NPRL2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to starvation#GO:0042594;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular response to amino acid starvation#GO:0034198;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GTPase-activating protein#PC00257;G-protein modulator#PC00022 DROME|FlyBase=FBgn0265189|UniProtKB=Q9I7H9 Q9I7H9 sud1 PTHR12117:SF0 HISTONE ACETYLTRANSFERASE COMPLEX PROLYL 3-HYDROXYLASE OGFOD1 dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of protein-containing complex disassembly#GO:0043244;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0053054|UniProtKB=Q8IPU1 Q8IPU1 Targ1 PTHR12521:SF0 PROTEIN C6ORF130 ADP-RIBOSE GLYCOHYDROLASE OARD1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleoside metabolic process#GO:0042278;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;purine-containing compound metabolic process#GO:0072521;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0040285|UniProtKB=Q9VXV6 Q9VXV6 Scamp PTHR10687:SF96 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network membrane#GO:0032588;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0038927|UniProtKB=Q9VD52 Q9VD52 CDC40 PTHR43979:SF1 PRE-MRNA-PROCESSING FACTOR 17 PRE-MRNA-PROCESSING FACTOR 17 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0026869|UniProtKB=Q9V4D8 Q9V4D8 Tdg PTHR12159:SF9 G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 DROME|FlyBase=FBgn0011566|UniProtKB=Q9W4X8 Q9W4X8 Smyd3 PTHR12197:SF251 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD EG:BACR7C10.4 PROTEIN histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0052264|UniProtKB=Q9VZN0 Q9VZN0 CG12604 PTHR12751:SF18 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 2 phosphatase modulator#PC00184 DROME|FlyBase=FBgn0030982|UniProtKB=Q9VWM3 Q9VWM3 Dmel\CG7423 PTHR24189:SF69 MYOTROPHIN MYOTROPHIN regulation of cellular component biogenesis#GO:0044087;regulation of actin filament depolymerization#GO:0030834;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;regulation of protein depolymerization#GO:1901879;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0032372|UniProtKB=Q9VKF7 Q9VKF7 Galml3 PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glucose metabolic process#GO:0006006;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 epimerase/racemase#PC00096 DROME|FlyBase=FBgn0032104|UniProtKB=Q9VLD7 Q9VLD7 aust PTHR16040:SF7 AUSTRALIN, ISOFORM A-RELATED AUSTRALIN, ISOFORM A-RELATED organelle localization#GO:0051640;nuclear division#GO:0000280;localization#GO:0051179;organelle fission#GO:0048285;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;mitotic metaphase chromosome alignment#GO:0007080;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;chromosome localization#GO:0050000 chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0261245|UniProtKB=Q9VXD1 Q9VXD1 sing PTHR22776:SF39 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEIN SINGLES BAR regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0263033|UniProtKB=B9ER12 B9ER12 CG30459-RA PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;cellular component organization#GO:0016043 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane contact site#GO:0044232;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0000179|UniProtKB=Q24432 Q24432 bi PTHR11267:SF181 T-BOX PROTEIN-RELATED OPTOMOTOR-BLIND PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 DROME|FlyBase=FBgn0038989|UniProtKB=Q9VCY1 Q9VCY1 Dmel\CG6937 PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DROME|FlyBase=FBgn0085468|UniProtKB=A8DYC4 A8DYC4 ND-MWFE PTHR17098:SF2 NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 DROME|FlyBase=FBgn0014869|UniProtKB=Q9VAN7 Q9VAN7 Pgam1 PTHR11931:SF33 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE phosphoglycerate mutase activity#GO:0004619;isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 mutase#PC00160;isomerase#PC00135 Glycolysis#P00024>Phosphoglyceromutase#P00680 DROME|FlyBase=FBgn0035953|UniProtKB=Q9VSS9 Q9VSS9 NM_140022.1 PTHR45700:SF3 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3B ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 DROME|FlyBase=FBgn0263772|UniProtKB=M9PJ12 M9PJ12 CG32778 PTHR10816:SF15 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0023535|UniProtKB=O76895 O76895 Arg PTHR43782:SF5 ARGINASE ARGINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0038189|UniProtKB=Q9VFP8 Q9VFP8 Art6 PTHR11006:SF124 PROTEIN ARGININE N-METHYLTRANSFERASE ARGININE METHYLTRANSFERASE 9-RELATED histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039713|UniProtKB=Q8MLY8 Q8MLY8 RpS8 PTHR10394:SF3 40S RIBOSOMAL PROTEIN S8 SMALL RIBOSOMAL SUBUNIT PROTEIN ES8 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0039430|UniProtKB=Q9VBE6 Q9VBE6 CT17296 PTHR48182:SF2 PROTEIN SERAC1 PROTEIN SERAC1 DROME|FlyBase=FBgn0033574|UniProtKB=Q7K508 Q7K508 Spn47C PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0032456|UniProtKB=Q7KTC0 Q7KTC0 MRP PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0001075|UniProtKB=P33450 P33450 ft PTHR24026:SF140 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN FAT 4 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 DROME|FlyBase=FBgn0036876|UniProtKB=Q9VW00 Q9VW00 Dmel\CG9451 PTHR11567:SF205 ACID PHOSPHATASE-RELATED GH28721P-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatase#PC00181 DROME|FlyBase=FBgn0033961|UniProtKB=Q6IDF5 Q6IDF5 ND-B15 PTHR15469:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0259193|UniProtKB=B7Z0P2 B7Z0P2 Ir94d PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0046876|UniProtKB=Q9VNL2 Q9VNL2 Obp83ef PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0029718|UniProtKB=Q9W4I3 Q9W4I3 mRpL30 PTHR15892:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0000286|UniProtKB=P20385 P20385 Cf2 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0015031|UniProtKB=Q9VMS1 Q9VMS1 cype PTHR48416:SF1 CYTOCHROME C OXIDASE SUBUNIT 6C CYTOCHROME C OXIDASE SUBUNIT 6C mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0037504|UniProtKB=Q8STI6 Q8STI6 Dmel\CG1142 PTHR21686:SF12 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DROME|FlyBase=FBgn0037059|UniProtKB=Q9VP67 Q9VP67 Dmel\CG10510 PTHR21625:SF0 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX SUBUNIT 2 cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium or flagellum-dependent cell motility#GO:0001539;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0027358|UniProtKB=Q9Y0V3 Q9Y0V3 Tim9b PTHR13172:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 B protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;mitochondrial intermembrane space#GO:0005758 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0083975|UniProtKB=A0A6H2EDS1 A0A6H2EDS1 Nlg4 PTHR43903:SF15 NEUROLIGIN NEUROLIGIN 4, ISOFORM F binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system development#GO:0007399;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;signaling#GO:0023052;endocytosis#GO:0006897;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;membrane assembly#GO:0071709;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular localization#GO:0051641;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;modulation of chemical synaptic transmission#GO:0050804;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0031759|UniProtKB=Q9VMJ7 Q9VMJ7 Kdm5 PTHR10694:SF148 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5 catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0050290|UniProtKB=Q8MKK3 Q8MKK3 Ppcdc PTHR14359:SF6 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Coenzyme A biosynthesis#P02736>Pantothenoylcysteine decarboxylase#P02883;Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 DROME|FlyBase=FBgn0038196|UniProtKB=Q9VFN9 Q9VFN9 dHYPK PTHR31184:SF2 HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER HUNTINGTIN-INTERACTING PROTEIN K regulation of protein stability#GO:0031647;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008 DROME|FlyBase=FBgn0039452|UniProtKB=Q9VBC2 Q9VBC2 Dmel\CG14245 PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0029661|UniProtKB=M9PDP1 M9PDP1 Dmel\CG16781 PTHR46283:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;cellular process#GO:0009987;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;regulation of mitochondrion organization#GO:0010821;protein modification by small protein conjugation#GO:0032446;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0020506|UniProtKB=O18408 O18408 Amyrel PTHR43447:SF61 ALPHA-AMYLASE ALPHA-AMYLASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 amylase#PC00048 DROME|FlyBase=FBgn0046214|UniProtKB=Q9VBX3 Q9VBX3 vig2 PTHR12299:SF17 HYALURONIC ACID-BINDING PROTEIN 4 AT19571P-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0038419|UniProtKB=Q9VEW5 Q9VEW5 BcDNA:RE20991 PTHR11346:SF147 GALECTIN GALECTIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0029800|UniProtKB=Q9W482 Q9W482 lin-52 PTHR31489:SF2 LIN52 FAMILY MEMBER PROTEIN LIN-52 HOMOLOG DROME|FlyBase=FBgn0020618|UniProtKB=O18640 O18640 Rack1 PTHR19868:SF0 RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 SMALL RIBOSOMAL SUBUNIT PROTEIN RACK1 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein binding#GO:0005515 protein metabolic process#GO:0019538;translation#GO:0006412;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;negative regulation of translation#GO:0017148;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;rescue of stalled cytosolic ribosome#GO:0072344;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;translational elongation#GO:0006414;gene expression#GO:0010467;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0013308|UniProtKB=P40808 P40808 Odc2 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586 biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 DROME|FlyBase=FBgn0024998|UniProtKB=O76861 O76861 EG:100G10.1 PTHR13361:SF1 WW DOMAIN-BINDING PROTEIN 11 WW DOMAIN-BINDING PROTEIN 11 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 DROME|FlyBase=FBgn0032256|UniProtKB=Q9VKU8 Q9VKU8 RluA-2 PTHR21600:SF40 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD2 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 RNA processing factor#PC00147 DROME|FlyBase=FBgn0050289|UniProtKB=Q8IRK5 Q8IRK5 Dmel\CG30289 PTHR24256:SF546 TRYPTASE-RELATED MIP11562P-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0038804|UniProtKB=Q9VDL4 Q9VDL4 Dmel\CG10877 PTHR48207:SF3 SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE SUCCINYL-COA:GLUTARATE COA-TRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 DROME|FlyBase=FBgn0029828|UniProtKB=Q9W452 Q9W452 Dmel\CG6067 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0021750|UniProtKB=Q9VF85 Q9VF85 SerRS-m PTHR11778:SF23 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0003450|UniProtKB=P05049 P05049 snk PTHR24260:SF147 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED DROME|FlyBase=FBgn0011270|UniProtKB=Q9VGB6 Q9VGB6 Pgam2 PTHR11931:SF33 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE isomerase activity#GO:0016853;phosphoglycerate mutase activity#GO:0004619;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;intramolecular phosphotransferase activity#GO:0016868 nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 mutase#PC00160;isomerase#PC00135 Glycolysis#P00024>Phosphoglyceromutase#P00680 DROME|FlyBase=FBgn0028387|UniProtKB=Q9VM15 Q9VM15 chm PTHR10615:SF222 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT7 N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;histone acetyltransferase activity#GO:0004402;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transcription regulator activity#GO:0140110;acetyltransferase activity#GO:0016407;binding#GO:0005488;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137 DROME|FlyBase=FBgn0032781|UniProtKB=Q9VIW7 Q9VIW7 RtcB PTHR11118:SF1 RNA-SPLICING LIGASE RTCB HOMOLOG RNA-SPLICING LIGASE RTCB catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0032889|UniProtKB=Q8SZU0 Q8SZU0 Dmel\CG9331 PTHR10996:SF119 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0002936|UniProtKB=P15425 P15425 ninaA PTHR11071:SF478 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, RHODOPSIN-SPECIFIC ISOZYME intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0002626|UniProtKB=P04359 P04359 RpL32 PTHR23413:SF1 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N 60S RIBOSOMAL PROTEIN L32 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 DROME|FlyBase=FBgn0031969|UniProtKB=B7Z031 B7Z031 pes PTHR11923:SF93 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 GH07959P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0034973|UniProtKB=Q9W1B2 Q9W1B2 Mic10c PTHR21304:SF0 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0040294|UniProtKB=Q7K4D1 Q7K4D1 POSH PTHR14167:SF51 SH3 DOMAIN-CONTAINING RING-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular adaptor activity#GO:0060090;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0015561|UniProtKB=Q4V5A3 Q4V5A3 unpg PTHR24334:SF0 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN UNPLUGGED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0036008|UniProtKB=Q9VT05 Q9VT05 CT11439 PTHR48051:SF78 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 59 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0036712|UniProtKB=Q8T8Z2 Q8T8Z2 brv2 PTHR10877:SF183 POLYCYSTIN FAMILY MEMBER AT14535P-RELATED ion channel#PC00133 DROME|FlyBase=FBgn0039156|UniProtKB=Q9VCC6 Q9VCC6 Dmel\CG6178 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 DROME|FlyBase=FBgn0259210|UniProtKB=B7YZQ3 B7YZQ3 prom PTHR11238:SF9 PROMININ ISOFORM D-RELATED PROMININ, ISOFORM D DROME|FlyBase=FBgn0032368|UniProtKB=Q9VKG2 Q9VKG2 spag4 PTHR12911:SF48 SAD1/UNC-84-LIKE PROTEIN-RELATED KLAROID PROTEIN-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane#GO:0016020;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0039282|UniProtKB=Q9VBX0 Q9VBX0 Bili PTHR13283:SF10 KREV INTERACTION TRAPPED 1-RELATED FERM DOMAIN-CONTAINING PROTEIN 8 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0260481|UniProtKB=Q8IPS7 Q8IPS7 Dmel\CG32454 PTHR43226:SF4 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO AMINOPEPTIDASE 3 aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153 DROME|FlyBase=FBgn0010488|UniProtKB=A1Z968 A1Z968 NAT1 PTHR23253:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2 RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;translation factor activity#GO:0180051 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 DROME|FlyBase=FBgn0035877|UniProtKB=Q9VSH9 Q9VSH9 CG7083 PTHR13465:SF4 UPF0183 PROTEIN PHAF1 PROTEIN CG7083 protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;protein localization to cell periphery#GO:1990778;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0037650|UniProtKB=Q9VHJ0 Q9VHJ0 Dmel\CG11977 PTHR10334:SF613 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0085466|UniProtKB=A8JRF0 A8JRF0 CG16918 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0026577|UniProtKB=Q9VID9 Q9VID9 BEST:LD19244 PTHR14296:SF16 REMODELING AND SPACING FACTOR 1 REMODELING AND SPACING FACTOR 1 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010 DROME|FlyBase=FBgn0040793|UniProtKB=Q9VVG5 Q9VVG5 COX7B PTHR22133:SF2 AT01821P-RELATED AT01821P-RELATED DROME|FlyBase=FBgn0034156|UniProtKB=A1ZAJ4 A1ZAJ4 Dmel\CG5348 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0037728|UniProtKB=Q9VH95 Q9VH95 cPges PTHR22932:SF1 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE CYTOSOLIC PROSTAGLANDIN E SYNTHASE protein binding#GO:0005515;Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein metabolic process#GO:0019538;chaperone-mediated protein complex assembly#GO:0051131;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072 DROME|FlyBase=FBgn0032382|UniProtKB=A0A4P1SA55 A0A4P1SA55 Mal-B2 PTHR10357:SF235 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A3-RELATED oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;amylase#PC00048 DROME|FlyBase=FBgn0003721|UniProtKB=P49455 P49455 Tm1 PTHR19269:SF45 TROPOMYOSIN TROPOMYOSIN-1, ISOFORMS 33_34 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;muscle contraction#GO:0006936;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;muscle system process#GO:0003012;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 actin binding motor protein#PC00040 DROME|FlyBase=FBgn0032191|UniProtKB=Q9VL28 Q9VL28 Snx17 PTHR12431:SF14 SORTING NEXIN 17 AND 27 LD15323P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;metabolic process#GO:0008152;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0261004|UniProtKB=Q9VNE4 Q9VNE4 asl PTHR43939:SF128 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 ASTERLESS protein-membrane adaptor activity#GO:0043495;cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;spindle localization#GO:0051653;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0037081|UniProtKB=Q7K204 Q7K204 barc PTHR15608:SF0 SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2 17S U2 SNRNP COMPLEX COMPONENT HTATSF1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin-protein adaptor activity#GO:0140463;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;localization#GO:0051179;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein localization to organelle#GO:0033365;RNA biosynthetic process#GO:0032774;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396 U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;chromosome#GO:0005694;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;site of double-strand break#GO:0035861;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;U2 snRNP#GO:0005686 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0027558|UniProtKB=Q9Y117 Q9Y117 Pgant3 PTHR11675:SF143 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 3 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0036935|UniProtKB=Q9VW76 Q9VW76 Dmel\CG14186 PTHR28388:SF1 TRANSMEMBRANE PROTEIN 237 TRANSMEMBRANE PROTEIN 237 cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;cilium#GO:0005929 DROME|FlyBase=FBgn0259704|UniProtKB=Q9VDZ4 Q9VDZ4 Nsun5 PTHR22807:SF4 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102 ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;rRNA modification#GO:0000154;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;methylation#GO:0032259;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;rRNA base methylation#GO:0070475;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of biosynthetic process#GO:0009891;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;positive regulation of translation#GO:0045727;rRNA processing#GO:0006364;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;rRNA metabolic process#GO:0016072 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0030674|UniProtKB=X2JF73 X2JF73 HUWE1 PTHR11254:SF445 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE HECT-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 DROME|FlyBase=FBgn0086444|UniProtKB=Q9VIZ3 Q9VIZ3 l(2)37Cb PTHR18934:SF83 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16 ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;helicase activity#GO:0004386 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0262870|UniProtKB=M9PE65 M9PE65 axo PTHR15036:SF88 PIKACHURIN-LIKE PROTEIN PIKACHURIN cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;developmental process#GO:0032502;multicellular organism development#GO:0007275 cell junction#GO:0030054;extracellular region#GO:0005576;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;basement membrane#GO:0005604 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0038166|UniProtKB=Q9VFS8 Q9VFS8 CG9588 PTHR12651:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0261823|UniProtKB=Q9V727 Q9V727 Asx PTHR13578:SF20 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASX binding#GO:0005488;chromatin binding#GO:0003682 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;PcG protein complex#GO:0031519;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0036211|UniProtKB=X2JGK6 X2JGK6 Dmel\CG5946 PTHR19370:SF219 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 reductase#PC00198;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0030306|UniProtKB=Q9VYY2 Q9VYY2 Spase25 PTHR13085:SF0 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;metabolic process#GO:0008152;biosynthetic process#GO:0009058;establishment of protein localization to endoplasmic reticulum#GO:0072599;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein metabolic process#GO:0019538;localization#GO:0051179;protein targeting#GO:0006605;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 DROME|FlyBase=FBgn0032156|UniProtKB=Q9VL73 Q9VL73 Dmel\CG13124 PTHR23254:SF17 EIF4G DOMAIN PROTEIN MIF4G DOMAIN-CONTAINING PROTEIN translation regulator activity#GO:0045182 post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030481|UniProtKB=Q9VYD6 Q9VYD6 Dmel\CG1662 PTHR11266:SF131 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 FI08002P-RELATED mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 DROME|FlyBase=FBgn0052656|UniProtKB=X2JBD0 X2JBD0 Muc11A PTHR20003:SF8 GLYCOPROTEIN-RELATED PROLINE-RICH PROTEIN BSTNI SUBFAMILY 3 DROME|FlyBase=FBgn0033079|UniProtKB=Q7K3U4 Q7K3U4 Fmo2 PTHR23023:SF266 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0034573|UniProtKB=Q9W2N5 Q9W2N5 Sou PTHR12170:SF3 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED GH10162P catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0040529|UniProtKB=Q9VHS2 Q9VHS2 COX7A PTHR10510:SF11 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0031395|UniProtKB=M9PB06 M9PB06 Dmel\CG10874 PTHR13400:SF4 CHEMOKINE C-C MOTIF RECEPTOR 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 28B-LIKE transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0001987|UniProtKB=Q7KT70 Q7KT70 Gli PTHR43903:SF28 NEUROLIGIN FI18641P1 binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;synaptic vesicle endocytosis#GO:0048488;regulation of cell communication#GO:0010646;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;signaling#GO:0023052;endocytosis#GO:0006897;synapse assembly#GO:0007416;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;cell surface#GO:0009986;synapse#GO:0045202;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0029937|UniProtKB=Q9W3S3 Q9W3S3 Dmel\CG8300 PTHR31206:SF1 LP10445P LP10445P DROME|FlyBase=FBgn0085491|UniProtKB=A8JNN4 A8JNN4 DmelCpr66Ca PTHR12236:SF100 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 50CA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0037323|UniProtKB=Q8I099 Q8I099 Dmel\CG2663 PTHR10174:SF230 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0031003|UniProtKB=Q9VWJ9 Q9VWJ9 Dmel\CG7889 PTHR14614:SF172 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039863|UniProtKB=Q7KRS9 Q7KRS9 Zmynd8 PTHR46453:SF5 PROTEIN KINASE C-BINDING PROTEIN 1 MYND-TYPE ZINC FINGER-CONTAINING CHROMATIN READER ZMYND8 ISOFORM X1-RELATED transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0035094|UniProtKB=Q0E8V8 Q0E8V8 Dmel\CG9380 PTHR11022:SF78 PEPTIDOGLYCAN RECOGNITION PROTEIN MIP09469P peptidoglycan muralytic activity#GO:0061783;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0052672|UniProtKB=Q9W2S2 Q9W2S2 Atg8a PTHR10969:SF33 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;GABA receptor binding#GO:0050811;phospholipid binding#GO:0005543;protein binding#GO:0005515;lipid binding#GO:0008289;binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899 protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;response to stress#GO:0006950;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;protein-containing complex disassembly#GO:0032984;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594 intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0051548|UniProtKB=Q8IPP8 Q8IPP8 Dmel\CG31548 PTHR43975:SF6 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED DROME|FlyBase=FBgn0034788|UniProtKB=Q9W1Y4 Q9W1Y4 Dmel\CG13532 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0033934|UniProtKB=Q4V6X9 Q4V6X9 Dmel\CG17385 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0001612|UniProtKB=Q9XYP8 Q9XYP8 Grip91 PTHR19302:SF14 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 3 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0050103|UniProtKB=A1ZAU0 A1ZAU0 BcDNA:AT08275 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 DROME|FlyBase=FBgn0261858|UniProtKB=Q6ILY6 Q6ILY6 Mzt1 PTHR28520:SF15 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;mitotic spindle assembly#GO:0090307;microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;chromosome organization#GO:0051276;microtubule polymerization#GO:0046785;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;nuclear division#GO:0000280;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0028902|UniProtKB=Q9V3M9 Q9V3M9 Tektin-A PTHR19960:SF31 TEKTIN TEKTIN plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;organelle assembly#GO:0070925 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0285943|UniProtKB=A1ZAH1 A1ZAH1 knon PTHR12700:SF12 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT D, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145 cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 DROME|FlyBase=FBgn0029706|UniProtKB=Q9W4K8 Q9W4K8 Pdpr PTHR13847:SF257 SARCOSINE DEHYDROGENASE-RELATED FI22513P1 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092 DROME|FlyBase=FBgn0270926|UniProtKB=Q7KTW9 Q7KTW9 AsnS PTHR11772:SF48 ASPARAGINE SYNTHETASE ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING] ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ligase#PC00142 Asparagine and aspartate biosynthesis#P02730>Asparagine synthetase#P02853 DROME|FlyBase=FBgn0053339|UniProtKB=Q9VC85 Q9VC85 CG13612 PTHR21253:SF0 F-BOX ONLY PROTEIN 11-RELATED F-BOX ONLY PROTEIN 11-RELATED DROME|FlyBase=FBgn0032801|UniProtKB=Q9VIU6 Q9VIU6 Dmel\CG10165 PTHR15422:SF45 OS05G0565100 PROTEIN ASCORBATE FERRIREDUCTASE (TRANSMEMBRANE) DROME|FlyBase=FBgn0262170|UniProtKB=A0A0B4K857 A0A0B4K857 chr2R_15474834_15475129.0 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0260748|UniProtKB=Q9VX80 Q9VX80 anon-15Db PTHR12156:SF5 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 FI18040P1 DROME|FlyBase=FBgn0050104|UniProtKB=Q8SZY4 Q8SZY4 NT5E-2 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 DROME|FlyBase=FBgn0030808|UniProtKB=Q9VX92 Q9VX92 RhoGAP15B PTHR45899:SF2 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phospholipid binding#GO:0005543 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0260862|UniProtKB=Q9W0N6 Q9W0N6 Vti1a PTHR21230:SF102 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A binding#GO:0005488;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle fusion#GO:0006906;catabolic process#GO:0009056;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;membrane fusion#GO:0061025;retrograde transport, endosome to Golgi#GO:0042147;membrane organization#GO:0061024;macroautophagy#GO:0016236;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization#GO:0051234;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;post-Golgi vesicle-mediated transport#GO:0006892;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;endosomal transport#GO:0016197;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840 transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 membrane traffic protein#PC00150;SNARE protein#PC00034 Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042 DROME|FlyBase=FBgn0030522|UniProtKB=Q9VY86 Q9VY86 amrt PTHR21016:SF4 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;positive regulation of Notch signaling pathway#GO:0045747;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 DROME|FlyBase=FBgn0031611|UniProtKB=Q9VR06 Q9VR06 FIG4 PTHR45738:SF5 POLYPHOSPHOINOSITIDE PHOSPHATASE POLYPHOSPHOINOSITIDE PHOSPHATASE phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;lipid modification#GO:0030258;dephosphorylation#GO:0016311;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0052270|UniProtKB=Q8IRE0 Q8IRE0 CG11530 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0002284|UniProtKB=P40304 P40304 Prosbeta6 PTHR11599:SF59 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-1 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039249|UniProtKB=Q9VC09 Q9VC09 Dmel\CG11168 PTHR24174:SF1 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 IP14385P regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0083985|UniProtKB=Q0KI27 Q0KI27 Dmel\CG34149 PTHR11728:SF8 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0037606|UniProtKB=Q9VHN8 Q9VHN8 Dmel\CG8032 PTHR10742:SF405 FLAVIN MONOAMINE OXIDASE LD37279P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidase#PC00175 DROME|FlyBase=FBgn0037721|UniProtKB=Q9VHA5 Q9VHA5 Dmel\CG9427 PTHR13234:SF68 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GH19763P catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0035424|UniProtKB=Q9I7T7 Q9I7T7 Larp4B PTHR22792:SF131 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN LARP4B RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031235|UniProtKB=Q9VPL8 Q9VPL8 Dmel\CG13693 PTHR15654:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 263 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271 cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014 DROME|FlyBase=FBgn0264606|UniProtKB=M9PE32 M9PE32 Fife PTHR12157:SF24 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN FIFE, ISOFORM D structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;regulation of exocytosis#GO:0017157;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;cellular component organization#GO:0016043;regulation of vesicle-mediated transport#GO:0060627;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of neurotransmitter secretion#GO:0046928;export from cell#GO:0140352;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulation of transport#GO:0051049;regulation of localization#GO:0032879;protein-containing complex organization#GO:0043933 synaptic membrane#GO:0097060;intracellular anatomical structure#GO:0005622;presynaptic active zone#GO:0048786;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;cell cortex#GO:0005938;membrane#GO:0016020;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0037895|UniProtKB=Q9VGP3 Q9VGP3 bumpel PTHR42985:SF38 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER BROTHER OF RUMPEL symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0038390|UniProtKB=Q9VF04 Q9VF04 Rbf2 PTHR13742:SF17 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RE32990P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;developmental process#GO:0032502;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle#GO:0045786;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0037347|UniProtKB=Q9VNE3 Q9VNE3 SecS PTHR12944:SF2 SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE nucleic acid binding#GO:0003676;binding#GO:0005488;tRNA binding#GO:0000049;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;post-transcriptional regulation of gene expression#GO:0010608;translational elongation#GO:0006414;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307;regulation of macromolecule metabolic process#GO:0060255;translation#GO:0006412;protein metabolic process#GO:0019538 DROME|FlyBase=FBgn0261597|UniProtKB=P13008 P13008 RpS26 PTHR12538:SF0 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0040324|UniProtKB=Q9V4E1 Q9V4E1 Ephrin PTHR11304:SF29 EPHRIN EPHRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 DROME|FlyBase=FBgn0030504|UniProtKB=Q9VYA7 Q9VYA7 CG2691 PTHR21576:SF2 UNCHARACTERIZED NODULIN-LIKE PROTEIN RRP12-LIKE PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0029849|UniProtKB=Q9W429 Q9W429 Efr PTHR10778:SF4 SOLUTE CARRIER FAMILY 35 MEMBER B NUCLEOTIDE SUGAR TRANSPORTER SLC35B4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleotide-sugar transmembrane transport#GO:0015780 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0031947|UniProtKB=Q9VLX2 Q9VLX2 Brd7-9 PTHR22881:SF48 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN CONTAINING 7_9 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0036063|UniProtKB=Q9VT74 Q9VT74 Dmel\CG6674 PTHR13445:SF3 TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 4 TSSC4 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN TSSC4 protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 DROME|FlyBase=FBgn0085521|UniProtKB=A8QI13 A8QI13 Dmel\CG40813 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;protein-containing complex organization#GO:0043933;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 DROME|FlyBase=FBgn0050091|UniProtKB=A1ZA34 A1ZA34 Dmel\CG30091 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0266435|UniProtKB=Q8MQY9 Q8MQY9 Dm GMCepsilon1 PTHR11552:SF226 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE RE28171P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037415|UniProtKB=Q9VNM8 Q9VNM8 Osi8 PTHR21879:SF14 FI03362P-RELATED-RELATED OSIRIS 8 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030038|UniProtKB=X2JEJ0 X2JEJ0 Dmel\CG1440 PTHR10363:SF2 BLEOMYCIN HYDROLASE BLEOMYCIN HYDROLASE aminopeptidase activity#GO:0004177;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 catabolic process#GO:0009056;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;response to toxic substance#GO:0009636;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;response to chemical#GO:0042221;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 DROME|FlyBase=FBgn0039883|UniProtKB=Q9V9S7 Q9V9S7 RhoGAP100F PTHR46150:SF3 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN 100F enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of Ras protein signal transduction#GO:0046578;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of biological process#GO:0050789;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;cell junction#GO:0030054 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0037440|UniProtKB=Q9VI16 Q9VI16 CRAT PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 DROME|FlyBase=FBgn0028675|UniProtKB=Q9VL32 Q9VL32 Sur PTHR24223:SF470 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER SUR establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0259824|UniProtKB=Q9VUW9 Q9VUW9 Hip14 PTHR24161:SF128 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE HIP14 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport#GO:0016192;neurotransmitter secretion#GO:0007269;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulated exocytosis#GO:0045055;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;exocytosis#GO:0006887;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;export from cell#GO:0140352;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0015372|UniProtKB=Q9V3C2 Q9V3C2 RabX1 PTHR24073:SF1223 DRAB5-RELATED LD47384P hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0020370|UniProtKB=Q9V6K1 Q9V6K1 TppII PTHR43806:SF14 PEPTIDASE S8 TRIPEPTIDYL-PEPTIDASE 2 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 serine protease#PC00203 DROME|FlyBase=FBgn0037298|UniProtKB=Q9VN86 Q9VN86 Sccpdh1 PTHR12286:SF5 SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0037621|UniProtKB=Q9VHM3 Q9VHM3 M1BP PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0037996|UniProtKB=Q9VGC5 Q9VGC5 Acsx5 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;lipid metabolic process#GO:0006629;nucleobase-containing compound biosynthetic process#GO:0034654;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 ligase#PC00142 DROME|FlyBase=FBgn0083940|UniProtKB=Q0KHU4 Q0KHU4 RhoU PTHR24072:SF142 RHO FAMILY GTPASE RHOU, ISOFORM B kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 response to stimulus#GO:0050896;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;supramolecular fiber organization#GO:0097435;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;actin filament organization#GO:0007015;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0039557|UniProtKB=Q9VAY7 Q9VAY7 CG12259 PTHR12722:SF0 XAP-5 PROTEIN-RELATED PROTEIN FAM50A cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0001229|UniProtKB=P22979 P22979 Hsp67Bc PTHR45640:SF40 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN 22-RELATED biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to heat#GO:0009408;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein refolding#GO:0042026;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0039325|UniProtKB=Q9VBS3 Q9VBS3 Dmel\CG10560 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0034157|UniProtKB=Q9V7U0 Q9V7U0 resilin PTHR12236:SF85 STRUCTURAL CONSTITUENT OF CUTICLE PRO-RESILIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0035309|UniProtKB=Q9W048 Q9W048 Dmel\CG15879 PTHR43329:SF4 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121 DROME|FlyBase=FBgn0035823|UniProtKB=Q9VSB6 Q9VSB6 eIF4E5 PTHR11960:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 DROME|FlyBase=FBgn0033652|UniProtKB=Q6Q7I9 Q6Q7I9 ths PTHR37458:SF1 THISBE THISBE cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039677|UniProtKB=Q9VAJ5 Q9VAJ5 ppk30 PTHR11690:SF288 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0028538|UniProtKB=Q9VJW1 Q9VJW1 Sec71 PTHR10663:SF415 GUANYL-NUCLEOTIDE EXCHANGE FACTOR LD29171P intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus subcompartment#GO:0098791 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0031034|UniProtKB=Q9VWG4 Q9VWG4 Dmel\CG14205 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0038326|UniProtKB=Q86BP1 Q86BP1 Hibch PTHR43176:SF38 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 hydrolase#PC00121 DROME|FlyBase=FBgn0026738|UniProtKB=Q9VUN9 Q9VUN9 Otud6 PTHR12419:SF10 OTU DOMAIN CONTAINING PROTEIN UBIQUITINYL HYDROLASE 1 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 cysteine protease#PC00081 DROME|FlyBase=FBgn0036860|UniProtKB=Q9VVY1 Q9VVY1 Dmel\CG14086 PTHR28474:SF1 TRANSMEMBRANE PROTEIN 72 TRANSMEMBRANE PROTEIN 72 DROME|FlyBase=FBgn0050184|UniProtKB=Q8MLR5 Q8MLR5 Dmel\CG30184 PTHR41152:SF8 AT26438P-RELATED AT26438P-RELATED DROME|FlyBase=FBgn0053689|UniProtKB=Q4ABJ1 Q4ABJ1 Dmel\CG33689 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0039015|UniProtKB=Q9VCV0 Q9VCV0 Takl2 PTHR23257:SF984 SERINE-THREONINE PROTEIN KINASE FI16976P1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0259222|UniProtKB=A4V362 A4V362 CG15690 PTHR19346:SF4 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0262987|UniProtKB=M9NDA3 M9NDA3 Dmel\CG43295 PTHR15863:SF2 MRN COMPLEX-INTERACTING PROTEIN MRN COMPLEX-INTERACTING PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0038961|UniProtKB=Q9VD14 Q9VD14 Dmel\CG13850 PTHR21228:SF69 FAST LEU-RICH DOMAIN-CONTAINING GH07286P-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA stability#GO:0043487;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147 DROME|FlyBase=FBgn0041630|UniProtKB=Q0E8H9 Q0E8H9 Hexo1 PTHR22600:SF61 BETA-HEXOSAMINIDASE BETA-N-ACETYLHEXOSAMINIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;lysosome#GO:0005764;cell periphery#GO:0071944;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 glycosidase#PC00110 DROME|FlyBase=FBgn0029645|UniProtKB=Q9W4U5 Q9W4U5 Dmel\CG14422 PTHR16021:SF13 MANSC DOMAIN CONTAINING PROTEIN 1 EARTHBOUND 1-RELATED DROME|FlyBase=FBgn0015793|UniProtKB=O18339 O18339 Rab19 PTHR24073:SF1125 DRAB5-RELATED RAS-RELATED PROTEIN RAB-43 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 DROME|FlyBase=FBgn0032085|UniProtKB=Q9VLF8 Q9VLF8 Dmel\CG9555 PTHR12242:SF49 OS02G0130600 PROTEIN-RELATED IP08657P-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0032723|UniProtKB=Q9VJ35 Q9VJ35 ssp3 PTHR31434:SF2 S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM DROME|FlyBase=FBgn0023181|UniProtKB=Q9W102 Q9W102 Orc4 PTHR12087:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 molecular adaptor activity#GO:0060090;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270 chromosome#GO:0005694;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nuclear origin of replication recognition complex#GO:0005664;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;membraneless organelle#GO:0043228 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0037486|UniProtKB=Q9VI79 Q9VI79 Dmel\CG14605 PTHR48021:SF33 FAMILY NOT NAMED AT22075P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0261291|UniProtKB=Q4AB33 Q4AB33 CheA86a PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0028500|UniProtKB=Q9V3C5 Q9V3C5 Rich PTHR22746:SF11 RAB6A-GEF COMPLEX PARTNER PROTEIN 1 GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;intracellular transport#GO:0046907;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;intracellular protein localization#GO:0008104;axon development#GO:0061564;axon guidance#GO:0007411;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular localization#GO:0051641;axonogenesis#GO:0007409;protein transport#GO:0015031;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cytosolic transport#GO:0016482;plasma membrane bounded cell projection morphogenesis#GO:0120039;intracellular protein transport#GO:0006886;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;endosomal transport#GO:0016197;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;guanyl-nucleotide exchange factor complex#GO:0032045;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0027495|UniProtKB=Q7KMH5 Q7KMH5 Smyd4-4 PTHR47111:SF1 BCDNA.LD29892 PROTEIN-LYSINE N-METHYLTRANSFERASE SMYD4 DROME|FlyBase=FBgn0010339|UniProtKB=P32234 P32234 128up PTHR43127:SF1 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 1 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0029067|UniProtKB=Q9VRG7 Q9VRG7 Dd PTHR12210:SF70 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 protein phosphatase#PC00195 DROME|FlyBase=FBgn0030411|UniProtKB=Q9VYK7 Q9VYK7 Dmel\CG2540 PTHR12192:SF2 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2 DROME|FlyBase=FBgn0038172|UniProtKB=Q9VFS1 Q9VFS1 Adgf-D PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000 nucleoside catabolic process#GO:0009164;purine-containing compound biosynthetic process#GO:0072522;purine nucleoside metabolic process#GO:0042278;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine-containing compound catabolic process#GO:0072523;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;cellular process#GO:0009987 cytosol#GO:0005829;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 deaminase#PC00088 DROME|FlyBase=FBgn0037044|UniProtKB=Q9VP87 Q9VP87 Pdss2 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 isoprenoid metabolic process#GO:0006720;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0052845|UniProtKB=Q8IRJ5 Q8IRJ5 Dmel\CG32845 PTHR10657:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED catalytic activity#GO:0003824;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072 DROME|FlyBase=FBgn0030915|UniProtKB=Q9VWV8 Q9VWV8 CG6179 PTHR13063:SF10 ENOS INTERACTING PROTEIN NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0003390|UniProtKB=Q9W3W5 Q9W3W5 shf PTHR14949:SF54 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 PROTEIN SHIFTED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0001224|UniProtKB=P02516 P02516 Hsp23 PTHR45640:SF40 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN 22-RELATED response to stress#GO:0006950;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;protein folding#GO:0006457;protein metabolic process#GO:0019538;protein refolding#GO:0042026 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|Gene_ORFName=Dmel_CG46506|UniProtKB=A0ACD4DAW3 A0ACD4DAW3 CG46506 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 DROME|FlyBase=FBgn0037873|UniProtKB=Q9VGS3 Q9VGS3 SdhC PTHR10978:SF5 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803 dehydrogenase#PC00092 TCA cycle#P00051>Succinate Dehydrogenase#P01273 DROME|FlyBase=FBgn0039818|UniProtKB=Q8SZ78 Q8SZ78 Mayo PTHR12011:SF481 ADHESION G-PROTEIN COUPLED RECEPTOR FI21270P1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0030786|UniProtKB=Q9VXB5 Q9VXB5 mRpL22 PTHR13501:SF10 CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 DROME|FlyBase=FBgn0042127|UniProtKB=Q9I7N3 Q9I7N3 Dmel\CG18789 PTHR46527:SF1 NUCLEOPORIN-LIKE PROTEIN 2 NUCLEOPORIN NUP42 transporter#PC00227 DROME|FlyBase=FBgn0033931|UniProtKB=A1Z9Q6 A1Z9Q6 Obp50e PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0022959|UniProtKB=Q95RE4 Q95RE4 yps PTHR11544:SF148 COLD SHOCK DOMAIN CONTAINING PROTEINS LD37574P binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0031443|UniProtKB=Q9VQE5 Q9VQE5 Prosbeta4R2 PTHR11599:SF6 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-2 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0051908|UniProtKB=Q8T9H8 Q8T9H8 ade3 PTHR31796:SF2 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ RNA-BINDING DOMAIN-CONTAINING DROME|FlyBase=FBgn0031760|UniProtKB=Q9VMJ6 Q9VMJ6 Tsp26A PTHR19282:SF431 TETRASPANIN TETRASPANIN 26A, ISOFORM B membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035859|UniProtKB=Q9VSG0 Q9VSG0 BcDNA:RE24439 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0038583|UniProtKB=Q9VEB6 Q9VEB6 Dmel\CG7183 PTHR15885:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0261445|UniProtKB=O02373 O02373 sgl PTHR11374:SF3 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0037521|UniProtKB=A0A0B4KGD9 A0A0B4KGD9 Dmel\CG2993 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0015872|UniProtKB=Q9V5Z7 Q9V5Z7 Drip PTHR19139:SF291 AQUAPORIN TRANSPORTER AQUAPORIN water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 fluid transport#GO:0042044;localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;transport#GO:0006810 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;apical part of cell#GO:0045177 transporter#PC00227 DROME|FlyBase=FBgn0001977|UniProtKB=Q9V3Y2 Q9V3Y2 CIAPIN1 PTHR13273:SF14 ANAMORSIN ANAMORSIN iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0264002|UniProtKB=M9PDT9 M9PDT9 MsR2 PTHR46273:SF15 MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0034060|UniProtKB=Q9V7H4 Q9V7H4 Tmem131 PTHR22050:SF3 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131 HOMOLOG biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0016754|UniProtKB=A8JR92 A8JR92 sba PTHR16112:SF16 METHYL-CPG BINDING PROTEIN, DROSOPHILA METHYL-CPG-BINDING DOMAIN PROTEIN 5_6 HOMOLOG SBA chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0015621|UniProtKB=Q9VPT8 Q9VPT8 Clp PTHR23102:SF24 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0038303|UniProtKB=Q9VFB7 Q9VFB7 SIDL PTHR13251:SF3 EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794 DROME|FlyBase=FBgn0032089|UniProtKB=Q9VLF2 Q9VLF2 Rcd-1r PTHR12262:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;P-body#GO:0000932;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;CCR4-NOT complex#GO:0030014 DROME|FlyBase=FBgn0069242|UniProtKB=Q9I7K5 Q9I7K5 eca PTHR22811:SF14 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN LP01981P-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737 membrane traffic protein#PC00150;vesicle coat protein#PC00235 DROME|FlyBase=FBgn0038735|UniProtKB=A0A0B4KHF1 A0A0B4KHF1 MICU3 PTHR12294:SF13 EF HAND DOMAIN FAMILY A1,A2-RELATED MITOCHONDRIAL CALCIUM UPTAKE 3, ISOFORM D cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;metal ion transport#GO:0030001;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0032671|UniProtKB=Q9VJ97 Q9VJ97 JMJD4 PTHR12480:SF6 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;dioxygenase activity#GO:0051213 positive regulation of cellular component organization#GO:0051130;positive regulation of protein metabolic process#GO:0051247;positive regulation of translation#GO:0045727;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein-containing complex disassembly#GO:0043244;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003277|UniProtKB=P04052 P04052 Polr2A PTHR19376:SF37 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0033729|UniProtKB=A1Z8Z2 A1Z8Z2 Cpr49Af PTHR10380:SF229 CUTICLE PROTEIN CUTICULAR PROTEIN 49AF, ISOFORM A extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0032677|UniProtKB=Q9VJ90 Q9VJ90 CG5790 PTHR44167:SF23 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036359|UniProtKB=Q9VU70 Q9VU70 CG14105 PTHR21405:SF0 CDNA SEQUENCE BC021608 TETRATRICOPEPTIDE REPEAT PROTEIN 36 DROME|FlyBase=FBgn0264855|UniProtKB=P91926 P91926 AP-2alpha PTHR22780:SF4 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583 membrane protein complex#GO:0098796;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;intracellular membrane-bounded organelle#GO:0043231;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;coated membrane#GO:0048475;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;clathrin vesicle coat#GO:0030125;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 DROME|FlyBase=FBgn0037891|UniProtKB=Q9VGQ1 Q9VGQ1 Dlst PTHR43416:SF5 DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220 DROME|FlyBase=FBgn0034258|UniProtKB=A1ZAX1 A1ZAX1 eIF3c PTHR13937:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 DROME|FlyBase=FBgn0264486|UniProtKB=Q6ILA6 Q6ILA6 BP1086 PTHR39956:SF1 GH09530P-RELATED GH09530P-RELATED DROME|FlyBase=FBgn0001186|UniProtKB=Q9W330 Q9W330 Hex-A PTHR19443:SF16 HEXOKINASE HEXOKINASE-2-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 DROME|FlyBase=FBgn0263391|UniProtKB=Q02645 Q02645 hts PTHR10672:SF44 ADDUCIN PROTEIN HU-LI TAI SHAO protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0028426|UniProtKB=Q8MKW7 Q8MKW7 RNaseZ PTHR12553:SF49 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;mitochondrial RNA 3'-end processing#GO:0000965;tRNA 3'-end processing#GO:0042780;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185 DROME|FlyBase=FBgn0032168|UniProtKB=Q9VL60 Q9VL60 Dmel\CG13126 PTHR21320:SF3 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED RIBOSOME ASSEMBLY PROTEIN METTL17, MITOCHONDRIAL chaperone#PC00072 DROME|FlyBase=FBgn0266557|UniProtKB=B7Z002 B7Z002 kis PTHR45623:SF62 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED KISMET, ISOFORM C ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0003141|UniProtKB=P48611 P48611 pr PTHR12589:SF10 PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE 6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0000024|UniProtKB=P07140 P07140 Ace PTHR43918:SF13 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 DROME|FlyBase=FBgn0004168|UniProtKB=P28285 P28285 5-HT1A PTHR24247:SF241 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2A-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 DROME|FlyBase=FBgn0030745|UniProtKB=Q9VXG9 Q9VXG9 Dmel\CG4239 PTHR12454:SF11 TRIMERIC INTRACELLULAR CATION CHANNEL GH25683P monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;potassium channel activity#GO:0005267 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;sarcoplasmic reticulum membrane#GO:0033017;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0020509|UniProtKB=O46202 O46202 Acp62F PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0015402|UniProtKB=Q24171 Q24171 ksr PTHR23257:SF998 SERINE-THREONINE PROTEIN KINASE AT08303P phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036152|UniProtKB=M9PC68 M9PC68 Dyro PTHR21505:SF8 MADF DOMAIN-CONTAINING PROTEIN-RELATED DPT-YFP REPRESSOR BY OVEREXPRESSION, ISOFORM D-RELATED DROME|FlyBase=FBgn0032870|UniProtKB=Q9VIL2 Q9VIL2 Dmel\CG2608 PTHR13498:SF3 SPERM ASSOCIATED ANTIGEN 7 SPERM-ASSOCIATED ANTIGEN 7 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0004003|UniProtKB=O44342 O44342 wbl PTHR12211:SF3 ENDOPLASMIC RETICULUM PROTEIN ERP29 PROTEIN WINDBEUTEL protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0029965|UniProtKB=Q9W3P4 Q9W3P4 Ir7b PTHR42643:SF52 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 11A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0050443|UniProtKB=Q4V6Y6 Q4V6Y6 Opbp PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0032400|UniProtKB=Q9VKC5 Q9VKC5 p8 PTHR17149:SF4 NUCLEAR PROTEIN 1 AND 2 RH17958P regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cell cycle#GO:0045786;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cell population proliferation#GO:0008285;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0032435|UniProtKB=Q9VK82 Q9VK82 Oatp33Eb PTHR11388:SF158 ORGANIC ANION TRANSPORTER ORGANIC ANION TRANSPORTING POLYPEPTIDE 33EB active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 transporter#PC00227 DROME|FlyBase=FBgn0039675|UniProtKB=Q9VAJ7 Q9VAJ7 ppk21 PTHR11690:SF288 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0026787|UniProtKB=Q9VPJ1 Q9VPJ1 Nhe1 PTHR10110:SF191 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 8 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075 import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814 organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0030309|UniProtKB=Q9VYX8 Q9VYX8 Dmel\CG1572 PTHR22776:SF92 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN LD04844P regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0008636|UniProtKB=Q9W2P8 Q9W2P8 hbn PTHR24329:SF570 HOMEOBOX PROTEIN ARISTALESS HOMEOBRAIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0030352|UniProtKB=Q9VYS5 Q9VYS5 sicily PTHR21181:SF13 ER membrane protein complex subunit 5-related NADH DEHYDROGENASE (UBIQUINONE) COMPLEX I, ASSEMBLY FACTOR 6 DROME|FlyBase=FBgn0260657|UniProtKB=Q9VZA4 Q9VZA4 CG42540 PTHR10264:SF127 BAND 7 PROTEIN-RELATED BAND 7 PROTEIN CG42540 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transporter regulator activity#GO:0141108 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0039656|UniProtKB=Q9VAM2 Q9VAM2 Dmel\CG11951 PTHR11533:SF253 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0037994|UniProtKB=Q9VGC7 Q9VGC7 eIF3d2 PTHR12399:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 eukaryotic translation initiation factor 3 complex#GO:0005852;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 DROME|FlyBase=FBgn0002631|UniProtKB=P13096 P13096 E(spl)m5-HLH PTHR10985:SF12 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED ENHANCER OF SPLIT M3 PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 DROME|FlyBase=FBgn0032216|UniProtKB=Q9VKZ8 Q9VKZ8 Usp14 PTHR43982:SF1 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 binding#GO:0005488;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of metabolic process#GO:0009892;regulation of ERAD pathway#GO:1904292;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of protein catabolic process#GO:0042176;regulation of cellular response to stress#GO:0080135;negative regulation of catabolic process#GO:0009895;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032598|UniProtKB=Q9VJI8 Q9VJI8 ChLD3 PTHR45985:SF5 FAMILY NOT NAMED CHITIN AND LDLR BINDING DEACETYLASE 3 DROME|FlyBase=FBgn0030512|UniProtKB=Q9VYA0 Q9VYA0 Nadsyn PTHR23090:SF9 NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;indole-containing compound metabolic process#GO:0042430;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;pyridine-containing compound metabolic process#GO:0072524;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142 DROME|FlyBase=FBgn0052425|UniProtKB=Q9VPD7 Q9VPD7 CG5100 PTHR21254:SF1 C2 DOMAIN-CONTAINING PROTEIN 3 C2 DOMAIN-CONTAINING PROTEIN 3 protein localization to centrosome#GO:0071539;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cilium assembly#GO:0060271;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein localization to cytoskeleton#GO:0044380;cell cycle#GO:0007049;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;centriole replication#GO:0007099;organelle assembly#GO:0070925;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;protein localization to microtubule organizing center#GO:1905508;localization#GO:0051179;cellular process#GO:0009987;cell projection assembly#GO:0030031;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840 centriole#GO:0005814;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 DROME|FlyBase=FBgn0032820|UniProtKB=A0A0U1RVK6 A0A0U1RVK6 Fbp PTHR11556:SF1 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE ISOZYME 2 sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;small molecule metabolic process#GO:0044281;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glucose metabolic process#GO:0006006;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0032883|UniProtKB=Q8SWT2 Q8SWT2 Rhau PTHR18934:SF274 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT DNA_RNA HELICASE DHX36 isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;binding#GO:0005488 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0033160|UniProtKB=Q7K3M5 Q7K3M5 Dhx15 PTHR18934:SF109 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0263916|UniProtKB=Q9VMB6 Q9VMB6 Ent2 PTHR10332:SF80 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2, ISOFORM A nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0013733|UniProtKB=A1Z9J3 A1Z9J3 shot PTHR23169:SF35 ENVOPLAKIN SHORT STOP, ISOFORM H cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;wound healing#GO:0042060;intermediate filament-based process#GO:0045103;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;response to stress#GO:0006950;response to wounding#GO:0009611;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;membrane#GO:0016020 intermediate filament#PC00129;intermediate filament binding protein#PC00130 DROME|FlyBase=FBgn0038127|UniProtKB=Q9VFY1 Q9VFY1 Dmel\CG8476 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788 chaperone#PC00072 DROME|FlyBase=FBgn0023529|UniProtKB=O46067 O46067 Grp170 PTHR45639:SF3 HSC70CB, ISOFORM G-RELATED HYPOXIA UP-REGULATED PROTEIN 1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227 Hsp70 family chaperone#PC00027;chaperone#PC00072 DROME|FlyBase=FBgn0085462|UniProtKB=A8JRH5 A8JRH5 CG15541 PTHR41152:SF8 AT26438P-RELATED AT26438P-RELATED DROME|FlyBase=FBgn0051454|UniProtKB=Q8INQ8 Q8INQ8 CG11740 PTHR12459:SF27 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 DROME|FlyBase=FBgn0003448|UniProtKB=P08044 P08044 sna PTHR24388:SF118 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 507 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0050073|UniProtKB=A1Z9Q3 A1Z9Q3 Obp50b PTHR21066:SF3 ODORANT-BINDING PROTEIN 59A-RELATED IP02236P DROME|FlyBase=FBgn0085231|UniProtKB=A8DYK0 A8DYK0 Dmel\CG34202 PTHR31294:SF8 FAMILY NOT NAMED DUF4657 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0036900|UniProtKB=Q9VW28 Q9VW28 Dmel\CG8765 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0033555|UniProtKB=Q7KR04 Q7KR04 RpS15Ab PTHR11758:SF16 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0040253|UniProtKB=Q9VGT2 Q9VGT2 Ugt35E1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 DROME|FlyBase=FBgn0003866|UniProtKB=P22265 P22265 tsh PTHR12487:SF7 TEASHIRT-RELATED PROTEIN TEASHIRT-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0040079|UniProtKB=Q9V3I3 Q9V3I3 pkaap PTHR13155:SF1 A-KINASE ANCHOR PROTEINS A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0085437|UniProtKB=X2JEC6 X2JEC6 CG32689 PTHR21344:SF1 RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 DROME|FlyBase=FBgn0036024|UniProtKB=Q9VT25 Q9VT25 Dmel\CG18180 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0029950|UniProtKB=Q9W3R0 Q9W3R0 rumpel PTHR42985:SF5 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER FI02094P-RELATED active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;sodium ion transport#GO:0006814 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0032968|UniProtKB=Q9V9P6 Q9V9P6 Dmel\CG11634 PTHR21644:SF0 AT02555P-RELATED AT02555P-RELATED DROME|FlyBase=FBgn0033921|UniProtKB=A1Z9P1 A1Z9P1 tej PTHR22948:SF84 TUDOR DOMAIN CONTAINING PROTEIN FI02030P-RELATED nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;cell differentiation#GO:0030154;anterior/posterior pattern specification#GO:0009952;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;anterior/posterior axis specification#GO:0009948;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;oogenesis#GO:0048477;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;sexual reproduction#GO:0019953;pattern specification process#GO:0007389;piRNA processing#GO:0034587;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;cell maturation#GO:0048469;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regionalization#GO:0003002;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;developmental maturation#GO:0021700 intracellular organelle#GO:0043229;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0034784|UniProtKB=Q9W1Z0 Q9W1Z0 Dmel\CG9826 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0010278|UniProtKB=Q05344 Q05344 Ssrp PTHR45849:SF7 FACT COMPLEX SUBUNIT SSRP1 FACT COMPLEX SUBUNIT SSRP1 protein binding#GO:0005515;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of chromatin organization#GO:1902275;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0035945|UniProtKB=Q8SZY7 Q8SZY7 Dmel\CG5026 PTHR10807:SF73 MYOTUBULARIN-RELATED LD06050P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;protein phosphatase binding#GO:0019903;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;hydrolase activity#GO:0016787 metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311;negative regulation of catabolic process#GO:0009895;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;phospholipid metabolic process#GO:0006644 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 DROME|FlyBase=FBgn0028983|UniProtKB=Q7JV69 Q7JV69 Spn55B PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0035410|UniProtKB=Q9VZT8 Q9VZT8 MnM PTHR13817:SF166 TITIN MYOMESIN AND MYOSIN BINDING PROTEIN structural protein#PC00211 DROME|FlyBase=FBgn0038981|UniProtKB=Q9VCZ2 Q9VCZ2 Dmel\CG5346 PTHR10209:SF885 OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN FI07970P-RELATED oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032101|UniProtKB=M9PD03 M9PD03 Dmel\CG9586 PTHR31684:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 DROME|FlyBase=FBgn0036750|UniProtKB=Q9VVK2 Q9VVK2 Dmel\CG6034 PTHR10742:SF398 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidase#PC00175 DROME|FlyBase=FBgn0036436|UniProtKB=Q9VUG2 Q9VUG2 Dmel\CG4914 PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0030722|UniProtKB=Q9VXK2 Q9VXK2 Spef1a PTHR12509:SF9 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERM FLAGELLAR PROTEIN 1 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014 DROME|FlyBase=FBgn0263511|UniProtKB=Q9W4B2 Q9W4B2 Vsx1 PTHR46892:SF3 VISUAL SYSTEM HOMEOBOX 2 VISUAL SYSTEM HOMEOBOX 2 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0036239|UniProtKB=X2JCC3 X2JCC3 Pop2 PTHR10797:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT POLY(A)-SPECIFIC RIBONUCLEASE 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540 regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 RNA metabolism protein#PC00031;RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0017578|UniProtKB=P91664 P91664 Max PTHR10328:SF3 PROTEIN MAX MYC-ASSOCIATED FACTOR X PROTEIN MAX transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Oxidative stress response#P00046>Max#P01133 DROME|FlyBase=FBgn0003319|UniProtKB=Q05319 Q05319 Sb PTHR24253:SF66 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEINASE STUBBLE catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0025726|UniProtKB=H9XVP2 H9XVP2 unc-13 PTHR10480:SF12 PROTEIN UNC-13 HOMOLOG UNC-13, ISOFORM E syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;calmodulin binding#GO:0005516;SNARE binding#GO:0000149 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0003447|UniProtKB=Q24524 Q24524 sn PTHR10551:SF9 FASCIN FASCIN-2 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;cytoskeleton organization#GO:0007010;cell migration#GO:0016477;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0035173|UniProtKB=Q9W0L6 Q9W0L6 Dmel\CG13907 PTHR11360:SF286 MONOCARBOXYLATE TRANSPORTER GH22266P-RELATED monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0037921|UniProtKB=Q7YZ91 Q7YZ91 Zaf1 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0036014|UniProtKB=Q9VT14 Q9VT14 bs17c12.y1 PTHR46437:SF1 MORN REPEAT-CONTAINING PROTEIN 5 MORN REPEAT-CONTAINING PROTEIN 5 DROME|FlyBase=FBgn0036745|UniProtKB=Q9VVJ7 Q9VVJ7 Sep15 PTHR13077:SF6 SELENOPROTEIN F SELENOPROTEIN F oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0033055|UniProtKB=A1Z6J5 A1Z6J5 Tbce PTHR15140:SF35 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE E binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0050394|UniProtKB=Q8SY25 Q8SY25 CG10500 PTHR22950:SF646 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 10 L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0264922|UniProtKB=O97102 O97102 Sumo PTHR10562:SF56 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein sumoylation#GO:0016925;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0038324|UniProtKB=Q9VF81 Q9VF81 Tmtc4 PTHR44227:SF3 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC4 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 glycoprotein biosynthetic process#GO:0009101;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;protein O-linked glycosylation via mannose#GO:0035269;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0038564|UniProtKB=Q9VED7 Q9VED7 Dmel\CG7785 PTHR20951:SF2 C13ORF1 PROTEIN-RELATED SPRY DOMAIN-CONTAINING PROTEIN 7 DROME|FlyBase=FBgn0037412|UniProtKB=A0A0B4KF52 A0A0B4KF52 Osi4 PTHR21879:SF21 FI03362P-RELATED-RELATED OSIRIS 4, ISOFORM B cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0040031|UniProtKB=A8Y5A2 A8Y5A2 Dmel\CG12061 PTHR10846:SF70 SODIUM/POTASSIUM/CALCIUM EXCHANGER ZYDECO, ISOFORM F calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034487|UniProtKB=Q7K2N1 Q7K2N1 Efhc1.2 PTHR12086:SF11 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2 regulation of anatomical structure morphogenesis#GO:0022603;developmental growth#GO:0048589;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;multicellular organism development#GO:0007275;neuromuscular junction development#GO:0007528;regulation of cell projection organization#GO:0031344;growth#GO:0040007;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;regulation of dendrite development#GO:0050773;synapse assembly#GO:0007416;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;cellular component organization#GO:0016043;regulation of dendrite morphogenesis#GO:0048814;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789 cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0031879|UniProtKB=E1JHA6 E1JHA6 uif PTHR12916:SF15 CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2 UNINFLATABLE, ISOFORM C signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;Notch signaling pathway#GO:0007219;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0267337|UniProtKB=Q9VI93 Q9VI93 rn PTHR23226:SF160 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ROTUND sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0028887|UniProtKB=Q9V453 Q9V453 BG:DS03323.1 PTHR12706:SF30 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH-RELATED DROME|FlyBase=FBgn0037781|UniProtKB=Q8T913 Q8T913 Fancl PTHR13206:SF0 UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN E3 UBIQUITIN-PROTEIN LIGASE FANCL catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0053346|UniProtKB=Q7KRX0 Q7KRX0 Dmel\CG33346 PTHR13966:SF19 ENDONUCLEASE RELATED DNA_RNA NON-SPECIFIC ENDONUCLEASE DOMAIN-CONTAINING PROTEIN-RELATED nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097 catabolic process#GO:0009056;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 DROME|FlyBase=FBgn0032907|UniProtKB=Q9VIH0 Q9VIH0 Nthl1 PTHR43286:SF7 ENDONUCLEASE III-LIKE PROTEIN 1 ENDONUCLEASE III-LIKE PROTEIN 1 hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;DNA N-glycosylase activity#GO:0019104 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 DROME|FlyBase=FBgn0029155|UniProtKB=E1JIZ4 E1JIZ4 Men-b PTHR23406:SF101 MALIC ENZYME-RELATED MALIC ENZYME-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176 DROME|FlyBase=FBgn0029888|UniProtKB=Q9W3X7 Q9W3X7 ND-ASHI PTHR12840:SF1 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0051774|UniProtKB=A0A023GPK8 A0A023GPK8 fred PTHR11640:SF134 NEPHRIN ECHINOID, ISOFORM A-RELATED binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0085638|UniProtKB=A0A0C4DHN2 A0A0C4DHN2 Dmel\CG41378 PTHR13234:SF82 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE-LIKE PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0036570|UniProtKB=Q95TS5 Q95TS5 IntS9 PTHR46094:SF1 INTEGRATOR COMPLEX SUBUNIT 9 INTEGRATOR COMPLEX SUBUNIT 9 snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0028744|UniProtKB=Q7K0Y1 Q7K0Y1 CG5033 PTHR17605:SF0 RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN RIBOSOME BIOGENESIS PROTEIN BOP1 nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle lumen#GO:0043233;90S preribosome#GO:0030686;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 ribosomal protein#PC00202 DROME|FlyBase=FBgn0039879|UniProtKB=Q9V9T2 Q9V9T2 Ir100a PTHR42643:SF48 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 100A transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0002533|UniProtKB=P07187 P07187 Lcp2 PTHR10380:SF230 CUTICLE PROTEIN CUTICULAR PROTEIN 47EE-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0290421|UniProtKB=Q9VBI2 Q9VBI2 Cmpk PTHR23359:SF206 NUCLEOTIDE KINASE UMP-CMP KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo pyrimidine ribonucleotides biosythesis#P02740>Uridylate kinase#P02924 DROME|FlyBase=FBgn0039620|UniProtKB=Q8MS59 Q8MS59 wat PTHR11011:SF60 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987 organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0039029|UniProtKB=Q9VCT5 Q9VCT5 Dmel\CG4704 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;metal ion transport#GO:0030001;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;transporter complex#GO:1990351;organelle membrane#GO:0031090 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0030607|UniProtKB=Q9VXY8 Q9VXY8 dob PTHR12406:SF41 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED TRIACYLGLYCEROL LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triacylglycerol lipase activity#GO:0004806;hydrolase activity#GO:0016787 lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;cellular process#GO:0009987;neutral lipid catabolic process#GO:0046461;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232 phospholipase#PC00186 DROME|FlyBase=FBgn0265767|UniProtKB=Q5LJX8 Q5LJX8 zyd PTHR10846:SF70 SODIUM/POTASSIUM/CALCIUM EXCHANGER ZYDECO, ISOFORM F potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0033978|UniProtKB=Q9V771 Q9V771 Cyp6a23 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0042710|UniProtKB=Q9NFT7 Q9NFT7 Hex-T PTHR19443:SF16 HEXOKINASE HEXOKINASE-2-RELATED hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 DROME|FlyBase=FBgn0051224|UniProtKB=Q9VE54 Q9VE54 CG7696 PTHR24383:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0001941|UniProtKB=Q94515 Q94515 ifc PTHR12879:SF8 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE DES1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 oxidoreductase#PC00176;hydroxylase#PC00122 DROME|FlyBase=FBgn0034566|UniProtKB=A0A0B4LG18 A0A0B4LG18 Dmel\CG9313 PTHR12442:SF11 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 1 binding#GO:0005488;protein binding#GO:0005515 organelle assembly#GO:0070925;cilium movement#GO:0003341;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036 membraneless organelle#GO:0043228;outer dynein arm#GO:0036157;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037581|UniProtKB=Q9VHR7 Q9VHR7 Dmel\CG7352 PTHR19265:SF0 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cilium#GO:0005929;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 DROME|FlyBase=FBgn0003963|UniProtKB=Q9VPQ6 Q9VPQ6 ush PTHR12958:SF3 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN USH transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;heart development#GO:0007507;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0263510|UniProtKB=A1Z8D0 A1Z8D0 nclb PTHR14091:SF0 PERIODIC TRYPTOPHAN PROTEIN 1 PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of transcription by RNA polymerase I#GO:0006356;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase I#GO:0045943;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0029703|UniProtKB=Q9W4L5 Q9W4L5 Dmel\CG12692 PTHR22667:SF0 AT01380P-RELATED AT01380P-RELATED DROME|FlyBase=FBgn0034612|UniProtKB=Q9W2I5 Q9W2I5 Dmel\CG10505 PTHR24223:SF324 ATP-BINDING CASSETTE SUB-FAMILY C LD17001P transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0036057|UniProtKB=Q9VT67 Q9VT67 Hez PTHR13542:SF0 LSM12 HOMOLOG PROTEIN LSM12 DROME|FlyBase=FBgn0038398|UniProtKB=Q9VEY9 Q9VEY9 sxe2 PTHR11610:SF169 LIPASE GH15759P-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0014427|UniProtKB=Q9VAN0 Q9VAN0 Psat PTHR43247:SF1 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE heterocyclic compound binding#GO:1901363;transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Vitamin B6 metabolism#P02787>Phosphoserine transaminase#P03227;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157;Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058 DROME|FlyBase=FBgn0037297|UniProtKB=A0A0C4DHA5 A0A0C4DHA5 Rgp1 PTHR12507:SF3 REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED RAB6A-GEF COMPLEX PARTNER PROTEIN 2 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197 cytoplasm#GO:0005737;endomembrane system#GO:0012505;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038395|UniProtKB=A0A126GUV0 A0A126GUV0 Jhbp5 PTHR11008:SF32 PROTEIN TAKEOUT-LIKE PROTEIN GH08336P-RELATED rhythmic process#GO:0048511;circadian rhythm#GO:0007623 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0000568|UniProtKB=P13055 P13055 Eip75B PTHR24082:SF473 NUCLEAR HORMONE RECEPTOR ECDYSONE-INDUCED PROTEIN 75B, ISOFORM B DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0028543|UniProtKB=Q7KTA1 Q7KTA1 NimB2 PTHR24047:SF32 FI01909P-RELATED FI01909P-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028327|UniProtKB=Q9W335 Q9W335 l(1)G0320 PTHR12924:SF0 TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0041235|UniProtKB=Q9W1U5 Q9W1U5 Gr59c PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0259967|UniProtKB=Q6IGA5 Q6IGA5 Sfp53D PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0034005|UniProtKB=Q9V7A4 Q9V7A4 ItgaPS4 PTHR23220:SF83 INTEGRIN ALPHA INTEGRIN ALPHA-PS3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941 DROME|FlyBase=FBgn0000411|UniProtKB=Q24533 Q24533 D PTHR10270:SF338 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0046880|UniProtKB=A1ZBP7 A1ZBP7 Obp56b PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0032170|UniProtKB=Q9VL57 Q9VL57 Dmel\CG4658 PTHR23354:SF108 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED RE10231P DROME|FlyBase=FBgn0264302|UniProtKB=Q9VS49 Q9VS49 wrm1 PTHR31395:SF26 SHISA GEO05642P1-RELATED scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0261797|UniProtKB=P37276 P37276 Dhc64C PTHR10676:SF404 DYNEIN HEAVY CHAIN FAMILY PROTEIN CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;microtubule motor activity#GO:0003777;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 nuclear migration#GO:0007097;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell motility#GO:0048870;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;axonal transport#GO:0098930;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;axo-dendritic transport#GO:0008088;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;mitotic cell cycle process#GO:1903047;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;spindle organization#GO:0007051;cell cycle process#GO:0022402;cellular component organization#GO:0016043;mitotic spindle organization#GO:0007052;cytoplasmic microtubule organization#GO:0031122;establishment of organelle localization#GO:0051656;retrograde axonal transport#GO:0008090;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoplasmic microtubule#GO:0005881;cell cortex#GO:0005938;dynein complex#GO:0030286 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0050463|UniProtKB=Q8MRC9 Q8MRC9 Pgant9 PTHR11675:SF131 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 9-RELATED hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0085432|UniProtKB=Q8IMA8 Q8IMA8 pan PTHR10373:SF38 TRANSCRIPTION FACTOR 7 FAMILY MEMBER PROTEIN PANGOLIN, ISOFORM J sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;RNA polymerase II transcription regulator complex#GO:0090575;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0039128|UniProtKB=Q9VCG0 Q9VCG0 Dmel\CG13599 PTHR15681:SF1 MAD2L1-BINDING PROTEIN MAD2L1-BINDING PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0031389|UniProtKB=Q9VQ75 Q9VQ75 Dmel\CG4259 PTHR24258:SF129 SERINE PROTEASE-RELATED LP15124P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0030218|UniProtKB=Q7KVQ8 Q7KVQ8 Dmel\CG1628 PTHR45624:SF63 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular localization#GO:0051641;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;L-alpha-amino acid transmembrane transport#GO:1902475;establishment of localization#GO:0051234;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0027093|UniProtKB=Q9VXN4 Q9VXN4 ArgRS PTHR11956:SF5 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0000182|UniProtKB=Q24009 Q24009 BicC PTHR10627:SF83 SCP160 PROTEIN BICAUDAL C intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0019644|UniProtKB=Q94516 Q94516 ATPsynB PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT B, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086 cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0013812|UniProtKB=A0A0B4KHJ4 A0A0B4KHJ4 Dhc93AB PTHR10676:SF36 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN AT 93AB, ISOFORM C isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544 microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294 axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0022774|UniProtKB=Q9VW26 Q9VW26 Oat PTHR11986:SF126 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 transaminase#PC00216 DROME|FlyBase=FBgn0015903|UniProtKB=A0A0B4KGD0 A0A0B4KGD0 apt PTHR21411:SF0 APONTIC REGULATORY PROTEIN ZESTE DROME|FlyBase=FBgn0039039|UniProtKB=Q962I0 Q962I0 lmd PTHR19818:SF153 ZINC FINGER PROTEIN ZIC AND GLI LD47926P RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0033529|UniProtKB=Q7K2L7 Q7K2L7 Pef PTHR46212:SF10 PEFLIN PEFLIN cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;protein-containing complex organization#GO:0043933;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 DROME|FlyBase=FBgn0040382|UniProtKB=Q9W5D6 Q9W5D6 EG:BACR19J1.3 PTHR38572:SF1 BCDNA.GH07269-RELATED BCDNA.GH07269-RELATED DROME|FlyBase=FBgn0032492|UniProtKB=Q9VK14 Q9VK14 Prosalpha6T PTHR11599:SF244 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;nucleus#GO:0005634;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0004781|UniProtKB=O97060 O97060 Ccp84Ac PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0032700|UniProtKB=Q9VJ63 Q9VJ63 Dmel\CG10338 PTHR12770:SF31 RUS1 FAMILY PROTEIN C16ORF58 RUS FAMILY MEMBER 1 DROME|FlyBase=FBgn0039887|UniProtKB=Q9V9S3 Q9V9S3 Pos PTHR12262:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 CCR4-NOT complex#GO:0030014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0250830|UniProtKB=Q9W5T4 Q9W5T4 anon-EST:Posey268 PTHR46388:SF2 NHL REPEAT-CONTAINING PROTEIN 2 NHL REPEAT-CONTAINING PROTEIN 2 DROME|FlyBase=FBgn0039006|UniProtKB=Q9VCW1 Q9VCW1 Cyp6d4 PTHR24292:SF93 CYTOCHROME P450 CYTOCHROME P450 310A1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0036871|UniProtKB=Q9VVZ5 Q9VVZ5 Dmel\CG14096 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0005655|UniProtKB=P17917 P17917 PCNA PTHR11352:SF0 PROLIFERATING CELL NUCLEAR ANTIGEN DNA SLIDING CLAMP PCNA enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;DNA replication#GO:0006260;DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA polymerase processivity factor#PC00015 DNA replication#P00017>PCNA#P00534 DROME|FlyBase=FBgn0052445|UniProtKB=Q8MR63 Q8MR63 Galml1 PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 epimerase/racemase#PC00096 DROME|FlyBase=FBgn0050378|UniProtKB=A1Z777 A1Z777 Dmel\CG30378 PTHR23050:SF552 CALCIUM BINDING PROTEIN AT16150P-RELATED binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;cation binding#GO:0043169;molecular function regulator activity#GO:0098772 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 DROME|FlyBase=FBgn0036607|UniProtKB=Q9VV31 Q9VV31 Dmel\CG13059 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0016984|UniProtKB=Q9W2R3 Q9W2R3 sktl PTHR23086:SF101 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE 59B, ISOFORM J-RELATED lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772 phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 kinase#PC00137;transferase#PC00220 DROME|FlyBase=FBgn0032763|UniProtKB=Q9VIY9 Q9VIY9 Dmel\CG17568 PTHR24390:SF291 ZINC FINGER PROTEIN GH23506P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0028684|UniProtKB=Q9V3V6 Q9V3V6 Rpt5 PTHR23073:SF7 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6A ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0004169|UniProtKB=P19351 P19351 up PTHR11521:SF1 TROPONIN T TROPONIN T, SKELETAL MUSCLE protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;multicellular organismal process#GO:0032501;system process#GO:0003008;cellular developmental process#GO:0048869;developmental process#GO:0032502;muscle contraction#GO:0006936;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 actin binding motor protein#PC00040 DROME|FlyBase=FBgn0052473|UniProtKB=Q8INH6 Q8INH6 CG8775 PTHR11533:SF306 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;catabolic process#GO:0009056;circulatory system process#GO:0003013;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;peptide hormone processing#GO:0016486;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;peptide catabolic process#GO:0043171;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;metabolic process#GO:0008152;system process#GO:0003008;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0035788|UniProtKB=Q9VS76 Q9VS76 Dmel\CG8541 PTHR39068:SF2 LARVAL/PUPAL CUTICLE PROTEIN H1C-LIKE PROTEIN-RELATED MIP24391P DROME|FlyBase=FBgn0263005|UniProtKB=Q9VYH2 Q9VYH2 Chpf PTHR12369:SF13 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE structural molecule activity#GO:0005198;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;protein complex scaffold activity#GO:0140378;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0039756|UniProtKB=Q9VA92 Q9VA92 anon-WO0118547.264 PTHR11351:SF61 ACYL-COA DESATURASE RH14937P oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;unsaturated fatty acid biosynthetic process#GO:0006636;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037534|UniProtKB=Q9VHX7 Q9VHX7 Elovl7 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0001133|UniProtKB=Q9U405 Q9U405 grau PTHR23225:SF2 ZINC FINGER PROTEIN AT09679P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0035805|UniProtKB=Q95SS8 Q95SS8 Tmem70 PTHR13281:SF0 TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0027601|UniProtKB=Q9VXZ8 Q9VXZ8 pdgy PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;organophosphate biosynthetic process#GO:0090407;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522 ligase#PC00142 DROME|FlyBase=FBgn0085470|UniProtKB=Q9VLJ5 Q9VLJ5 lmgB PTHR46949:SF1 LEUCINE REPEAT ADAPTER PROTEIN 25 AT07979P2 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0265264|UniProtKB=E2QCS7 E2QCS7 Dmel\CG17097 PTHR11005:SF144 LYSOSOMAL ACID LIPASE-RELATED AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0030989|UniProtKB=Q9VWL5 Q9VWL5 Inx5 PTHR11893:SF43 INNEXIN INNEXIN INX4-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cell communication#GO:0007154;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 gap junction#PC00105 DROME|FlyBase=FBgn0010501|UniProtKB=O02002 O02002 Dcp-1 PTHR10454:SF253 CASPASE CASPASE DRICE-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233 regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;biological regulation#GO:0065007;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033190|UniProtKB=A1Z707 A1Z707 Gpo2 PTHR11985:SF15 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 dehydrogenase#PC00092 DROME|FlyBase=FBgn0011206|UniProtKB=Q24207 Q24207 bol PTHR11176:SF62 BOULE-RELATED PROTEIN BOULE translation regulator activity#GO:0045182 regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;positive regulation of protein metabolic process#GO:0051247;regulation of translational initiation#GO:0006446;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of translation#GO:0045727;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030085|UniProtKB=Q9W393 Q9W393 Dmel\CG6999 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0032690|UniProtKB=Q9VJ74 Q9VJ74 Dmel\CG10333 PTHR47958:SF56 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX23-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA helicase#PC00032 DROME|FlyBase=FBgn0037038|UniProtKB=Q8T429 Q8T429 SP191 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0039228|UniProtKB=Q9VC34 Q9VC34 Dmel\CG6980 PTHR46540:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 12 TETRATRICOPEPTIDE REPEAT PROTEIN 12 cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0052529|UniProtKB=Q9VWC0 Q9VWC0 Hers PTHR46576:SF1 BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0288229|UniProtKB=Q8IPV3 Q8IPV3 Dmel\CG3164 PTHR48041:SF6 ABC TRANSPORTER G FAMILY MEMBER 28 PROTEIN WHITE-LIKE PROTEIN active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0003227|UniProtKB=Q9VF30 Q9VF30 rec PTHR11630:SF47 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR REC intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0259818|UniProtKB=Q9VPK5 Q9VPK5 CG11620 PTHR21567:SF88 CLASP CLASP N-TERMINAL DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;spindle organization#GO:0007051;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic sister chromatid segregation#GO:0000070;establishment of spindle localization#GO:0051293;mitotic spindle assembly#GO:0090307;cellular localization#GO:0051641;spindle localization#GO:0051653;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;establishment of organelle localization#GO:0051656;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cell cortex#GO:0005938;kinetochore#GO:0000776;cytoplasmic microtubule#GO:0005881;chromosome#GO:0005694;basal part of cell#GO:0045178;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;cell periphery#GO:0071944;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;spindle#GO:0005819;microtubule organizing center#GO:0005815;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0031174|UniProtKB=Q9VRG8 Q9VRG8 Dmel\CG1486 PTHR42735:SF1 FAMILY NOT NAMED PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;cellular process#GO:0009987;lipid catabolic process#GO:0016042;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0262717|UniProtKB=Q9GPJ1 Q9GPJ1 Skel PTHR24036:SF13 SKELETOR-RELATED PROTEIN SKELETOR, ISOFORMS D_E transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0039241|UniProtKB=Q9VC18 Q9VC18 BEST:GH11240 PTHR11692:SF0 BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 De novo purine biosynthesis#P02738>AICAR transformylase#P02900;De novo purine biosynthesis#P02738>IMP cyclohydrolase#P02894 DROME|FlyBase=FBgn0036044|UniProtKB=Q9VT49 Q9VT49 Zasp67 PTHR24214:SF38 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN ZASP-RELATED binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;actomyosin#GO:0042641;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;stress fiber#GO:0001725;cytoskeleton#GO:0005856;actin filament#GO:0005884;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;adherens junction#GO:0005912 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0259246|UniProtKB=A0A0B4K7K9 A0A0B4K7K9 brp PTHR18861:SF5 ELKS/RAB6-INTERACTING/CAST PROTEIN PROTEIN BRUCHPILOT structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cell periphery#GO:0071944;cell cortex#GO:0005938;presynapse#GO:0098793;presynaptic active zone#GO:0048786;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0035954|UniProtKB=Q9VST0 Q9VST0 Doc3 PTHR11267:SF204 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR 3B DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 DROME|FlyBase=FBgn0033952|UniProtKB=Q7KGG1 Q7KGG1 Adgf-E PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;nucleoside catabolic process#GO:0009164;purine-containing compound biosynthetic process#GO:0072522;purine nucleoside metabolic process#GO:0042278;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;adenosine metabolic process#GO:0046085;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleobase metabolic process#GO:0006144;small molecule biosynthetic process#GO:0044283 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cytosol#GO:0005829 deaminase#PC00088 DROME|FlyBase=FBgn0051960|UniProtKB=Q8IQ15 Q8IQ15 CG10022 PTHR23050:SF547 CALCIUM BINDING PROTEIN AT10229P-RELATED ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0027610|UniProtKB=Q9Y166 Q9Y166 Dic1 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310 C4-dicarboxylate transport#GO:0015740;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;cellular process#GO:0009987;succinate transport#GO:0015744;phosphate ion transport#GO:0006817;dicarboxylic acid transport#GO:0006835;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0033810|UniProtKB=A1Z9A2 A1Z9A2 CG4646 PTHR12857:SF0 CXXC MOTIF CONTAINING ZINC BINDING PROTEIN CXXC MOTIF CONTAINING ZINC BINDING PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;ion binding#GO:0043167;transition metal ion binding#GO:0046914 DROME|FlyBase=FBgn0033610|UniProtKB=Q7JRP4 Q7JRP4 CG18335 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 CILIARY MICROTUBULE INNER PROTEIN 2B DROME|FlyBase=FBgn0033761|UniProtKB=A1Z934 A1Z934 Dmel\CG8778 PTHR11941:SF171 ENOYL-COA HYDRATASE-RELATED SD19268P catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;lyase#PC00144;hydratase#PC00120 DROME|FlyBase=FBgn0041243|UniProtKB=Q9V4K2 Q9V4K2 Gr43a PTHR21143:SF123 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR FOR SUGAR TASTE 43A-RELATED dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;cell body#GO:0044297;neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0062449|UniProtKB=Q8SX38 Q8SX38 BcDNA:RE27552 PTHR10367:SF9 MRNA-CAPPING ENZYME RNA_RNP COMPLEX-1-INTERACTING PHOSPHATASE transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 RNA processing factor#PC00147;mRNA capping factor#PC00145 DROME|FlyBase=FBgn0286852|UniProtKB=Q8SZ46 Q8SZ46 naz PTHR24320:SF294 RETINOL DEHYDROGENASE NADP-RETINOL DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0022981|UniProtKB=A0A0B4K691 A0A0B4K691 rpk PTHR11690:SF288 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0038043|UniProtKB=Q9VG76 Q9VG76 Mycbp PTHR13168:SF0 ASSOCIATE OF C-MYC AMY-1 C-MYC-BINDING PROTEIN transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 PDGF signaling pathway#P00047>c-Myc#P01172 DROME|FlyBase=FBgn0037410|UniProtKB=Q9VNM3 Q9VNM3 Osi2 PTHR21879:SF10 FI03362P-RELATED-RELATED LP14110P membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030673|UniProtKB=Q9VXR4 Q9VXR4 Dmel\CG15601 PTHR21505:SF8 MADF DOMAIN-CONTAINING PROTEIN-RELATED DPT-YFP REPRESSOR BY OVEREXPRESSION, ISOFORM D-RELATED DROME|FlyBase=FBgn0032859|UniProtKB=Q9VIM5 Q9VIM5 Arpc2 PTHR12058:SF0 ARP2/3 COMPLEX 34 KDA SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015 nucleus#GO:0005634;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 DROME|FlyBase=FBgn0032225|UniProtKB=Q9VKY7 Q9VKY7 Frmd5 PTHR23280:SF32 4.1 G PROTEIN FI22325P1 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0289744|UniProtKB=Q7JXB9 Q7JXB9 EndoG PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536 catabolic process#GO:0009056;apoptotic process#GO:0006915;cell death#GO:0008219;execution phase of apoptosis#GO:0097194;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 organelle membrane#GO:0031090;cytoplasm#GO:0005737;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967 Apoptosis signaling pathway#P00006>endoG#P00279 DROME|FlyBase=FBgn0037780|UniProtKB=Q9VH36 Q9VH36 ohgt PTHR14255:SF4 CEREBLON PROTEIN CEREBLON enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039490|UniProtKB=Q9VB72 Q9VB72 Dmel\CG5882 PTHR32083:SF0 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 structural protein#PC00211 DROME|FlyBase=FBgn0039068|UniProtKB=A0A0B4K701 A0A0B4K701 Pex11c PTHR20990:SF1 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11C cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;peroxisome organization#GO:0007031;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0052262|UniProtKB=Q9VZM6 Q9VZM6 CG10854 PTHR11266:SF8 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN 2 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0039163|UniProtKB=Q9VCB9 Q9VCB9 Dmel\CG5515 PTHR12292:SF9 RWD DOMAIN-CONTAINING PROTEIN RWD DOMAIN-CONTAINING PROTEIN 1 signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;response to steroid hormone#GO:0048545;biological regulation#GO:0065007;nuclear receptor-mediated signaling pathway#GO:0141193;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;signal transduction#GO:0007165;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;cellular process#GO:0009987;response to hormone#GO:0009725;cellular response to steroid hormone stimulus#GO:0071383 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053017|UniProtKB=A1ZAC8 A1ZAC8 CG15703 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0259932|UniProtKB=E1JI98 E1JI98 Dmel\CG42455 PTHR36877:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 13 SMALL INTEGRAL MEMBRANE PROTEIN 13 DROME|FlyBase=FBgn0034035|UniProtKB=Q8SXU3 Q8SXU3 Gmppa PTHR22572:SF104 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE REGULATORY SUBUNIT ALPHA transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 DROME|FlyBase=FBgn0036264|UniProtKB=Q9VTV2 Q9VTV2 Dmel\CG11529 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0031664|UniProtKB=Q7K4I5 Q7K4I5 Dmel\CG8892 PTHR23322:SF6 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 7 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031043|UniProtKB=M9PI14 M9PI14 Naa20A PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596 regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248 acetyltransferase#PC00038 DROME|FlyBase=FBgn0032442|UniProtKB=Q9VK72 Q9VK72 Nepl7 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0038662|UniProtKB=Q7KSC4 Q7KSC4 Mpc1 PTHR14154:SF3 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;intracellular transport#GO:0046907;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 DROME|FlyBase=FBgn0066114|UniProtKB=O97422 O97422 GlcAT-I PTHR10896:SF72 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE I hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0035695|UniProtKB=Q9VRW2 Q9VRW2 Dmel\CG10226 PTHR24221:SF503 ATP-BINDING CASSETTE SUB-FAMILY B MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49-RELATED active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0010620|UniProtKB=Q7K5M6 Q7K5M6 Sip1 PTHR14191:SF3 PDZ DOMAIN CONTAINING PROTEIN GH04176P-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0010894|UniProtKB=Q9VRM3 Q9VRM3 sinu PTHR21284:SF6 EG:80H7.2 PROTEIN SINUOUS anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure size#GO:0090066;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cell-cell junction#GO:0005911;apical junction complex#GO:0043296;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;tight junction#GO:0070160;cell junction#GO:0030054 DROME|FlyBase=FBgn0037687|UniProtKB=Q9VHE4 Q9VHE4 Dmel\CG8132 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 hydrolase#PC00121 DROME|FlyBase=FBgn0260648|UniProtKB=Q8IPX7 Q8IPX7 Rrp40 PTHR21321:SF1 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP40 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;macromolecule catabolic process#GO:0009057;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;snRNA 3'-end processing#GO:0034472;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;maturation of 5.8S rRNA#GO:0000460;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA processing factor#PC00147 DROME|FlyBase=FBgn0010611|UniProtKB=Q7K4Q9 Q7K4Q9 Hmgs PTHR43323:SF2 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;acetyl-CoA metabolic process#GO:0006084;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA synthase#P00498 DROME|FlyBase=FBgn0032251|UniProtKB=Q9VKV4 Q9VKV4 Nse4 PTHR16140:SF0 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0037008|UniProtKB=Q9VPD5 Q9VPD5 mTerf3 PTHR13068:SF112 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL mitochondrial ribosome assembly#GO:0061668;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;organelle assembly#GO:0070925;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0035161|UniProtKB=Q9W0M9 Q9W0M9 Dmel\CG13898 PTHR23050:SF552 CALCIUM BINDING PROTEIN AT16150P-RELATED molecular function regulator activity#GO:0098772;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;cation binding#GO:0043169 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 DROME|FlyBase=FBgn0016697|UniProtKB=Q95083 Q95083 Prosalpha5 PTHR11599:SF14 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-5 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502;nucleus#GO:0005634 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0030141|UniProtKB=Q9W329 Q9W329 Gga PTHR45905:SF1 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488 cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization within membrane#GO:0051668;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0085211|UniProtKB=A8DYY3 A8DYY3 RpS28-like PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN ES28 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 DROME|FlyBase=FBgn0032143|UniProtKB=Q9VL87 Q9VL87 Dmel\CG4017 PTHR11705:SF156 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B RH39904P-RELATED catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0030582|UniProtKB=Q9VY15 Q9VY15 Dmel\CG14411 PTHR10807:SF110 MYOTUBULARIN-RELATED FI17948P1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 DROME|FlyBase=FBgn0085477|UniProtKB=A8DYT7 A8DYT7 CG9966 PTHR11610:SF177 LIPASE IP13478P-RELATED hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0050098|UniProtKB=Q4V653 Q4V653 Dmel\CG30098 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0030484|UniProtKB=Q8MRM0 Q8MRM0 GstT4 PTHR43917:SF8 FAMILY NOT NAMED GH16740P-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220 DROME|FlyBase=FBgn0031413|UniProtKB=Q9VQA8 Q9VQA8 Dmel\CG9967 PTHR33963:SF2 MKRN2 OPPOSITE STRAND PROTEIN MKRN2 OPPOSITE STRAND PROTEIN DROME|FlyBase=FBgn0289712|UniProtKB=Q9W2N0 Q9W2N0 cpa PTHR10653:SF0 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of actin filament depolymerization#GO:0030834;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0011455|UniProtKB=Q9VTU2 Q9VTU2 ND-SGDH PTHR13178:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SGDH SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 5, MITOCHONDRIAL transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 DROME|FlyBase=FBgn0035497|UniProtKB=Q9VZI4 Q9VZI4 CT34848 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410 DROME|FlyBase=FBgn0038208|UniProtKB=Q9VFM5 Q9VFM5 Dmel\CG14355 PTHR39079:SF1 FI08034P-RELATED GH11706P-RELATED DROME|FlyBase=FBgn0031213|UniProtKB=Q9VPI6 Q9VPI6 galectin PTHR11346:SF196 GALECTIN GALECTIN carbohydrate binding#GO:0030246;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0036556|UniProtKB=M9PFN0 M9PFN0 hzg PTHR12210:SF202 DULLARD PROTEIN PHOSPHATASE PHOSPHATASE HERZOG catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 DROME|FlyBase=FBgn0014007|UniProtKB=P16620 P16620 Ptp69D PTHR19134:SF495 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE 69D hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;biological regulation#GO:0065007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DROME|FlyBase=FBgn0036263|UniProtKB=Q9VTV1 Q9VTV1 thoc6 PTHR44411:SF1 THO COMPLEX SUBUNIT 6 HOMOLOG THO COMPLEX SUBUNIT 6 biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DROME|FlyBase=FBgn0010220|UniProtKB=Q07886 Q07886 Dbp45A PTHR24031:SF761 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX49-RELATED metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0050379|UniProtKB=A1Z773 A1Z773 Dmel\CG30379 PTHR23291:SF131 BAX INHIBITOR-RELATED TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873 cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0031406|UniProtKB=Q9VQA0 Q9VQA0 Send1 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0001324|UniProtKB=Q9VW47 Q9VW47 kto PTHR46007:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 general transcription factor#PC00259 DROME|FlyBase=FBgn0001285|UniProtKB=Q7JX43 Q7JX43 Jon44E PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0030318|UniProtKB=Q9VYW6 Q9VYW6 rho-4 PTHR45840:SF8 RHOMBOID-RELATED PROTEIN RHOMBOID-4 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 DROME|FlyBase=FBgn0039691|UniProtKB=Q9VAH9 Q9VAH9 IntS11 PTHR11203:SF37 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER INTEGRATOR COMPLEX SUBUNIT 11 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 DROME|FlyBase=FBgn0038886|UniProtKB=Q9VDA5 Q9VDA5 Ugt49B2 PTHR48043:SF60 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0032405|UniProtKB=Q9VKB8 Q9VKB8 firl PTHR24322:SF754 PKSB SHORT-CHAIN DEHYDROGENASE_REDUCTASE 3 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092 DROME|FlyBase=FBgn0040363|UniProtKB=Q9V3E4 Q9V3E4 EG:BACR42I17.3 PTHR21461:SF83 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030509|UniProtKB=Q9VYA2 Q9VYA2 Dmel\CG11162 PTHR11863:SF241 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 oxidase#PC00175 DROME|FlyBase=FBgn0286785|UniProtKB=O44386 O44386 scb PTHR23220:SF83 INTEGRIN ALPHA INTEGRIN ALPHA-PS3-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 DROME|FlyBase=FBgn0266615|UniProtKB=A0A0B4LH46 A0A0B4LH46 Dmel\CG45122 PTHR37932:SF1 SMALL LYSINE-RICH PROTEIN 1 SMALL LYSINE-RICH PROTEIN 1 DROME|FlyBase=FBgn0052251|UniProtKB=Q8IRB5 Q8IRB5 Claspin PTHR14396:SF10 CLASPIN CLASPIN DROME|FlyBase=FBgn0032378|UniProtKB=Q9VKF0 Q9VKF0 CycY PTHR14248:SF40 CYCLIN Y, ISOFORM A CYCLIN Y, ISOFORM A kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0029945|UniProtKB=Q7KVU5 Q7KVU5 Acsf3 PTHR24096:SF435 LONG-CHAIN-FATTY-ACID--COA LIGASE MALONATE--COA LIGASE ACSF3, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 ligase#PC00142 DROME|FlyBase=FBgn0283427|UniProtKB=B7Z001 B7Z001 FASN1 PTHR43775:SF37 FATTY ACID SYNTHASE FATTY ACID SYNTHASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 DROME|FlyBase=FBgn0032434|UniProtKB=Q9VK83 Q9VK83 Dmel\CG5421 PTHR12471:SF7 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;homeostatic process#GO:0042592 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane#GO:0016020;proton-transporting V-type ATPase complex#GO:0033176;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;ATPase complex#GO:1904949 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0004066|UniProtKB=P22769 P22769 Prosalpha4 PTHR11599:SF237 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7-1-RELATED macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 proteasome complex#GO:0000502;nucleus#GO:0005634;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0033339|UniProtKB=A0A0B4LEZ1 A0A0B4LEZ1 Sec31 PTHR13923:SF11 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31A localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120 membrane traffic protein#PC00150;vesicle coat protein#PC00235 DROME|FlyBase=FBgn0000662|UniProtKB=Q9Y091 Q9Y091 fl(2)d PTHR15217:SF0 WILMS' TUMOR 1-ASSOCIATING PROTEIN PRE-MRNA-SPLICING REGULATOR WTAP enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of RNA metabolic process#GO:0051252;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;methyltransferase complex#GO:0034708 DROME|FlyBase=FBgn0037838|UniProtKB=Q9VGW2 Q9VGW2 TTLL15 PTHR47113:SF1 LD09343P LD09343P DROME|FlyBase=FBgn0037759|UniProtKB=Q9VH61 Q9VH61 Dmel\CG8526 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040 DROME|FlyBase=FBgn0000617|UniProtKB=Q27272 Q27272 Taf9 PTHR48068:SF4 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467 peptidase complex#GO:1905368;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 DROME|FlyBase=FBgn0036240|UniProtKB=Q7K155 Q7K155 Dmel\CG6928 PTHR11814:SF282 SULFATE TRANSPORTER SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0035090|UniProtKB=Q9W0X1 Q9W0X1 cg2736 PTHR11923:SF89 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 GH15894P cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0015000|UniProtKB=Q24173 Q24173 betaggt-I PTHR11774:SF4 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0037562|UniProtKB=Q9VHT9 Q9VHT9 Nazo PTHR31493:SF1 NAZO FAMILY MEMBER PROTEIN C19ORF12 process utilizing autophagic mechanism#GO:0061919;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;catabolic process#GO:0009056;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;cellular process#GO:0009987;autophagy#GO:0006914;monoatomic ion homeostasis#GO:0050801 organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039106|UniProtKB=Q9VCJ3 Q9VCJ3 Dmel\CG10301 PTHR10174:SF216 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN-RELATED phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0051005|UniProtKB=Q9V9Z3 Q9V9Z3 qless PTHR12001:SF89 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;isoprenoid metabolic process#GO:0006720 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 DROME|FlyBase=FBgn0026239|UniProtKB=Q9VE13 Q9VE13 gukh PTHR12902:SF23 WASP-1 WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER protein kinase A regulatory subunit binding#GO:0034237;binding#GO:0005488;protein kinase A binding#GO:0051018;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of organelle organization#GO:0010638;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0031313|UniProtKB=Q7K3E2 Q7K3E2 Dmel\CG5080 PTHR39960:SF1 LD34147P LD34147P DROME|FlyBase=FBgn0265001|UniProtKB=Q9VL88 Q9VL88 ppk18 PTHR11690:SF253 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 18-RELATED monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0039494|UniProtKB=Q9VB68 Q9VB68 grass PTHR24260:SF140 AT07769P-RELATED RH69521P-RELATED DROME|FlyBase=FBgn0029094|UniProtKB=Q9V464 Q9V464 asf1 PTHR12040:SF0 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1 histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0035512|UniProtKB=Q9VZG0 Q9VZG0 Cpr64Ac PTHR12236:SF104 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 64AC-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0026393|UniProtKB=P81918 P81918 Or43b PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0035021|UniProtKB=Q2PE14 Q2PE14 CG4622 PTHR13316:SF0 ZINC FINGER, CCHC DOMAIN CONTAINING 8 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0283499|UniProtKB=P09208 P09208 InR PTHR24416:SF525 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN-LIKE RECEPTOR transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;glucose homeostasis#GO:0042593;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;regulation of MAPK cascade#GO:0043408;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;homeostatic process#GO:0042592;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;transferase complex#GO:1990234;signaling receptor complex#GO:0043235;protein kinase complex#GO:1902911;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 transmembrane signal receptor#PC00197 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;PI3 kinase pathway#P00048>IR#P01187;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885 DROME|FlyBase=FBgn0259211|UniProtKB=P13002 P13002 grh PTHR11037:SF20 TRANSCRIPTION FACTOR CP2 PROTEIN GRAINYHEAD sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0035817|UniProtKB=Q9VSA9 Q9VSA9 Dmel\CG7409 PTHR45640:SF40 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN 22-RELATED response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;protein refolding#GO:0042026;gene expression#GO:0010467;protein maturation#GO:0051604;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;response to stress#GO:0006950;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 DROME|FlyBase=FBgn0038798|UniProtKB=Q9VDM1 Q9VDM1 Or92a PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0019940|UniProtKB=O01668 O01668 Rh6 PTHR24240:SF85 OPSIN OPSIN RH1-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;detection of stimulus#GO:0051606;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 DROME|FlyBase=FBgn0031231|UniProtKB=Q9VPL3 Q9VPL3 mRpL10 PTHR11560:SF15 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL10M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0000206|UniProtKB=P22815 P22815 boss PTHR24060:SF175 METABOTROPIC GLUTAMATE RECEPTOR PROTEIN BRIDE OF SEVENLESS glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0085408|UniProtKB=A1Z9P3 A1Z9P3 Shrm PTHR15012:SF32 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 cytoskeleton organization#GO:0007010;cell morphogenesis#GO:0000902;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;developmental process#GO:0032502 membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical junction complex#GO:0043296;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cell cortex#GO:0005938 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0005533|UniProtKB=P17704 P17704 RpS17 PTHR10732:SF0 40S RIBOSOMAL PROTEIN S17 SMALL RIBOSOMAL SUBUNIT PROTEIN ES17 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 DROME|FlyBase=FBgn0026761|UniProtKB=A1Z6L9 A1Z6L9 Trap1 PTHR11528:SF44 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL-RELATED purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;ATP-dependent activity#GO:0140657;protein kinase binding#GO:0019901;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072;Hsp90 family chaperone#PC00028 DROME|FlyBase=FBgn0026397|UniProtKB=P81910 P81910 Or22b PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0033708|UniProtKB=A1Z8V9 A1Z8V9 Dmel\CG8850 PTHR11616:SF339 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943 sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;glycine transport#GO:0015816;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;import into cell#GO:0098657;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 DROME|FlyBase=FBgn0029892|UniProtKB=Q9W3X3 Q9W3X3 Dph7 PTHR46042:SF1 DIPHTHINE METHYLTRANSFERASE DIPHTHINE METHYLTRANSFERASE cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 DROME|FlyBase=FBgn0085390|UniProtKB=Q01583 Q01583 Dgk PTHR11255:SF48 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE 1 lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;kinase#PC00137 DROME|FlyBase=FBgn0037949|UniProtKB=Q9VGI1 Q9VGI1 prd1 PTHR46556:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of biological process#GO:0050789;Golgi organization#GO:0007030;lysosome localization#GO:0032418;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;organelle localization#GO:0051640;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 DROME|FlyBase=FBgn0030799|UniProtKB=Q8SY58 Q8SY58 Dmel\CG4872 PTHR13812:SF24 KETIMINE REDUCTASE MU-CRYSTALLIN KETIMINE REDUCTASE MU-CRYSTALLIN hormone binding#GO:0042562;binding#GO:0005488 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;reductase#PC00198 DROME|FlyBase=FBgn0027784|UniProtKB=Q9V437 Q9V437 Prp18 PTHR13007:SF19 PRE-MRNA SPLICING FACTOR-RELATED PRE-MRNA-SPLICING FACTOR 18 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0260942|UniProtKB=Q9VCY7 Q9VCY7 bond PTHR11157:SF103 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0034513|UniProtKB=A1ZBU9 A1ZBU9 Dmel\CG13423 PTHR10363:SF2 BLEOMYCIN HYDROLASE BLEOMYCIN HYDROLASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 metabolic process#GO:0008152;sulfur compound catabolic process#GO:0044273;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carboxylic acid catabolic process#GO:0046395;sulfur compound metabolic process#GO:0006790;amino acid metabolic process#GO:0006520;response to chemical#GO:0042221;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;response to toxic substance#GO:0009636;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 DROME|FlyBase=FBgn0032899|UniProtKB=Q9VIH9 Q9VIH9 CG9338 PTHR33562:SF18 ATILLA, ISOFORM B-RELATED-RELATED RE19849P-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0058002|UniProtKB=Q7PL91 Q7PL91 ND-AGGG PTHR15223:SF1 NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0026309|UniProtKB=Q9UAS6 Q9UAS6 cmtr2 PTHR16121:SF2 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 2 O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0034070|UniProtKB=A1ZA87 A1ZA87 SP2353 PTHR15036:SF97 PIKACHURIN-LIKE PROTEIN SP2353, ISOFORM A system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;extracellular region#GO:0005576;cell junction#GO:0030054 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0264357|UniProtKB=Q9VDD2 Q9VDD2 SNF4Agamma PTHR13780:SF166 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT LD22662P nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;cation binding#GO:0043169;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;cellular response to nutrient levels#GO:0031669;regulation of carbohydrate metabolic process#GO:0006109;cellular response to starvation#GO:0009267;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to glucose starvation#GO:0042149;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to nutrient levels#GO:0031667;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;cellular response to stress#GO:0033554;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to starvation#GO:0042594 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase modulator#PC00140 DROME|FlyBase=FBgn0035253|UniProtKB=A8JNI2 A8JNI2 Srrm234 PTHR36562:SF5 SERINE/ARGININE REPETITIVE MATRIX 2 SERINE_ARGININE REPETITIVE MATRIX 2 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0025777|UniProtKB=Q0E8S7 Q0E8S7 homer PTHR10918:SF7 HOMER HOMER, ISOFORM E G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;cell surface receptor signaling pathway#GO:0007166;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425 DROME|FlyBase=FBgn0030610|UniProtKB=Q9VXY5 Q9VXY5 Cox17 PTHR16719:SF0 CYTOCHROME C OXIDASE COPPER CHAPERONE CYTOCHROME C OXIDASE COPPER CHAPERONE molecular carrier activity#GO:0140104 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840 mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0053964|UniProtKB=Q86NX3 Q86NX3 CG13174 PTHR12496:SF9 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0029708|UniProtKB=Q9W4K2 Q9W4K2 CG3556 PTHR10559:SF18 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN II small molecule binding#GO:0036094;binding#GO:0005488;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906 localization#GO:0051179;vitamin transport#GO:0051180;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;transport#GO:0006810 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0287630|UniProtKB=Q9VKS7 Q9VKS7 dbf PTHR46786:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 3 ZINC FINGER MATRIN-TYPE PROTEIN 3 RNA metabolism protein#PC00031;RNA processing factor#PC00147 p53 pathway#P00059>PAG608#G04690 DROME|FlyBase=FBgn0031255|UniProtKB=Q9VPP9 Q9VPP9 BBS8 PTHR44177:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 8 TETRATRICOPEPTIDE REPEAT PROTEIN 8 cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;BBSome#GO:0034464;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0001092|UniProtKB=P07487 P07487 Gapdh2 PTHR10836:SF76 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891 purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 DROME|FlyBase=FBgn0015781|UniProtKB=Q9V3F8 Q9V3F8 P5cr PTHR11645:SF69 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 metabolite interconversion enzyme#PC00262;reductase#PC00198 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 DROME|FlyBase=FBgn0037478|UniProtKB=Q9VI70 Q9VI70 NEST:bs33f03 PTHR21231:SF7 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 3 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0035469|UniProtKB=Q9VZL6 Q9VZL6 Lamtor4 PTHR33967:SF1 RAGULATOR COMPLEX PROTEIN LAMTOR4 RAGULATOR COMPLEX PROTEIN LAMTOR4 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 DROME|FlyBase=FBgn0030854|UniProtKB=Q9VX35 Q9VX35 CC4 PTHR22812:SF112 CHROMOBOX PROTEIN CHROMATOR, ISOFORM A-RELATED binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0033918|UniProtKB=Q7K0W1 Q7K0W1 Dmel\CG8531 PTHR44157:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;cellular component organization or biogenesis#GO:0071840 chaperone#PC00072 DROME|FlyBase=FBgn0038197|UniProtKB=Q95V55 Q95V55 foxo PTHR45767:SF2 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898 DROME|FlyBase=FBgn0038704|UniProtKB=Q8MSG8 Q8MSG8 CG5316 PTHR12486:SF4 APRATAXIN-RELATED APRATAXIN DNA binding#GO:0003677;hydrolase activity#GO:0016787;RNA binding#GO:0003723;double-stranded DNA binding#GO:0003690;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;double-stranded RNA binding#GO:0003725;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;damaged DNA binding#GO:0003684 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 DROME|FlyBase=FBgn0031930|UniProtKB=Q9VLZ1 Q9VLZ1 Dmel\CG7025 PTHR11705:SF123 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 DOMAIN-CONTAINING PROTEIN-RELATED metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0033579|UniProtKB=Q7JVS8 Q7JVS8 anon-WO0170980.143 PTHR46273:SF4 MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED AT19640P G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036484|UniProtKB=Q9VUL8 Q9VUL8 Pex3 PTHR28080:SF1 PEROXISOMAL BIOGENESIS FACTOR 3 PEROXISOMAL BIOGENESIS FACTOR 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein transport#GO:0015031;peroxisomal transport#GO:0043574;cellular localization#GO:0051641;localization#GO:0051179;peroxisome organization#GO:0007031;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778 DROME|FlyBase=FBgn0264672|UniProtKB=Q9VQB7 Q9VQB7 Eogt PTHR20961:SF148 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0013683|UniProtKB=P18934 P18934 mt:ND4L PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 DROME|FlyBase=FBgn0259878|UniProtKB=Q86NV3 Q86NV3 Fs PTHR10913:SF45 FOLLISTATIN-RELATED AGRIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0038397|UniProtKB=Q9VEZ2 Q9VEZ2 Dmel\CG10185 PTHR19871:SF14 BETA TRANSDUCIN-RELATED PROTEIN NACHT DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0039741|UniProtKB=Q7K483 Q7K483 Dmel\CG7943 PTHR46131:SF1 SD08549P SD08549P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;purine nucleotide transmembrane transporter activity#GO:0015216 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0037116|UniProtKB=Q9VNZ8 Q9VNZ8 Als2 PTHR46089:SF2 ALSIN HOMOLOG ALSIN HOMOLOG protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0042173|UniProtKB=A1Z758 A1Z758 143303_at PTHR10211:SF0 DEOXYRIBODIPYRIMIDINE PHOTOLYASE DEOXYRIBODIPYRIMIDINE PHOTO-LYASE carbon-carbon lyase activity#GO:0016830;deoxyribodipyrimidine photo-lyase activity#GO:0003904;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;lyase activity#GO:0016829 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;photoreactive repair#GO:0000719;pyrimidine dimer repair#GO:0006290;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 lyase#PC00144 DROME|FlyBase=FBgn0032048|UniProtKB=Q9VLK4 Q9VLK4 Dh31 PTHR41146:SF1 DIURETIC HORMONE CLASS 2 DIURETIC HORMONE CLASS 2 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of circadian rhythm#GO:0042752;cellular process#GO:0009987;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 DROME|FlyBase=FBgn0033601|UniProtKB=A1Z8H5 A1Z8H5 Cpr47Ed PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0043001|UniProtKB=Q9V452 Q9V452 Chrac-16 PTHR10252:SF153 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0035255|UniProtKB=Q9W0A7 Q9W0A7 RabX5 PTHR47977:SF18 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-36 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 small GTPase#PC00208 DROME|FlyBase=FBgn0083946|UniProtKB=Q4V516 Q4V516 lobo PTHR35249:SF2 DYNEIN REGULATORY COMPLEX SUBUNIT 7 DYNEIN REGULATORY COMPLEX SUBUNIT 7 flagellated sperm motility#GO:0030317;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm motility#GO:0097722;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414 cilium#GO:0005929;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0067783|UniProtKB=Q9VDL7 Q9VDL7 DPCoAC PTHR24089:SF736 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42 organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 DROME|FlyBase=FBgn0031058|UniProtKB=Q9VWD8 Q9VWD8 SPH158 PTHR24256:SF546 TRYPTASE-RELATED MIP11562P-RELATED catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0028986|UniProtKB=Q9VII7 Q9VII7 Spn38F PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0260997|UniProtKB=D2A6L3 D2A6L3 Dmel\CG42598 PTHR21113:SF4 AGAP001705-PA CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0051674|UniProtKB=Q8INU6 Q8INU6 CG9332 PTHR10996:SF119 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0033919|UniProtKB=Q0E980 Q0E980 Dmel\CG8547 PTHR41156:SF1 AGAP006184-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0044020|UniProtKB=Q7JWH5 Q7JWH5 Roc2 PTHR11210:SF60 RING BOX RING-BOX PROTEIN 2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul5-RING ubiquitin ligase complex#GO:0031466 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0040389|UniProtKB=Q9W4Z2 Q9W4Z2 mRpL14 PTHR21037:SF3 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0036496|UniProtKB=Q9VUN2 Q9VUN2 cocoon PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0086371|UniProtKB=Q9VFW4 Q9VFW4 Elp6 PTHR16184:SF6 ELONGATOR COMPLEX PROTEIN 6 ELONGATOR COMPLEX PROTEIN 6 protein-containing complex#GO:0032991;elongator holoenzyme complex#GO:0033588;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0031478|UniProtKB=Q9VQI6 Q9VQI6 Acbp7 PTHR23310:SF77 ACYL-COA-BINDING PROTEIN, ACBP LD25952P heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0260393|UniProtKB=F3YDE1 F3YDE1 CG17147-RA PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0036671|UniProtKB=Q9VVB4 Q9VVB4 CG9951 PTHR15668:SF5 JM1 PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 22 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;regulation of protein metabolic process#GO:0051246;vesicle-mediated transport#GO:0016192;positive regulation of macromolecule metabolic process#GO:0010604;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;endosomal transport#GO:0016197;regulation of biological process#GO:0050789;endocytic recycling#GO:0032456;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;regulation of intracellular signal transduction#GO:1902531;cellular localization#GO:0051641;positive regulation of metabolic process#GO:0009893;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular transport#GO:0046907;regulation of catabolic process#GO:0009894;vesicle-mediated transport to the plasma membrane#GO:0098876;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;localization within membrane#GO:0051668;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;localization#GO:0051179 DROME|FlyBase=FBgn0031098|UniProtKB=Q9VR80 Q9VR80 Dmel\CG17068 PTHR45774:SF11 BTB/POZ DOMAIN-CONTAINING LP10161P nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;cellular process#GO:0009987;neurogenesis#GO:0022008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0045476|UniProtKB=P83296 P83296 Gr64e PTHR21421:SF29 GUSTATORY RECEPTOR GUSTATORY RECEPTOR 5A FOR TREHALOSE-RELATED sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;system process#GO:0003008 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036286|UniProtKB=Q9VTX8 Q9VTX8 CG10616 PTHR33966:SF1 PROTEIN ODR-4 HOMOLOG PROTEIN ODR-4 HOMOLOG intracellular protein localization#GO:0008104;localization#GO:0051179;macromolecule localization#GO:0033036 DROME|FlyBase=FBgn0037218|UniProtKB=Q9VMY8 Q9VMY8 aux PTHR22967:SF105 SERINE/THREONINE PROTEIN KINASE CYCLIN-G-ASSOCIATED KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034618|UniProtKB=Q9W2H8 Q9W2H8 Agl PTHR10569:SF2 GLYCOGEN DEBRANCHING ENZYME GLYCOGEN DEBRANCHING ENZYME hydrolase activity#GO:0016787;glucosidase activity#GO:0015926;glycosyltransferase activity#GO:0016757;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hexosyltransferase activity#GO:0016758 polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;glycogen catabolic process#GO:0005980;generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170 DROME|FlyBase=FBgn0024986|UniProtKB=O76877 O76877 Dmel\CG3719 PTHR43601:SF5 THIOREDOXIN, MITOCHONDRIAL EG:132E8.3 PROTEIN cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0053113|UniProtKB=E1JHT6 E1JHT6 Rtnl1 PTHR45799:SF2 RETICULON-LIKE PROTEIN RETICULON-LIKE PROTEIN cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;endoplasmic reticulum tubular network organization#GO:0071786;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axon#GO:0030424;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0031051|UniProtKB=Q9VWE7 Q9VWE7 Ranbp21 PTHR11223:SF3 EXPORTIN 1/5 EXPORTIN-5 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 DROME|FlyBase=FBgn0010660|UniProtKB=Q9W1X4 Q9W1X4 Nup214 PTHR23193:SF46 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP214 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907 nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 transporter#PC00227 DROME|FlyBase=FBgn0032733|UniProtKB=Q9VJ24 Q9VJ24 Dmel\CG15170 PTHR21721:SF27 GH09876P-RELATED GH09876P DROME|FlyBase=FBgn0035657|UniProtKB=Q9VRS0 Q9VRS0 alphaKap4 PTHR23316:SF28 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 DROME|FlyBase=FBgn0051823|UniProtKB=Q8IP31 Q8IP31 Dmel\CG31823 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 serine protease#PC00203 DROME|FlyBase=FBgn0025712|UniProtKB=Q8T0T9 Q8T0T9 BEST:CK00246 PTHR13163:SF2 SPINAL CORD EXPRESSION PROTEIN 4 TRANSMEMBRANE PROTEIN 35B cellular component assembly#GO:0022607;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;protein-containing complex organization#GO:0043933;chaperone-mediated protein complex assembly#GO:0051131 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0028516|UniProtKB=Q9V471 Q9V471 ZnT35C PTHR11562:SF105 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER RE54080P-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;response to stimulus#GO:0050896;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;response to metal ion#GO:0010038;response to chemical#GO:0042221;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0023510|UniProtKB=Q9W543 Q9W543 Rbcn-3B PTHR44099:SF4 RABCONNECTIN-3B, ISOFORM A RABCONNECTIN-3B, ISOFORM A cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0033766|UniProtKB=A0A0B4K859 A0A0B4K859 Nup188 PTHR31431:SF1 NUCLEOPORIN NUP188 HOMOLOG NUCLEOPORIN NUP188 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;establishment of RNA localization#GO:0051236;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 transporter#PC00227 DROME|FlyBase=FBgn0037569|UniProtKB=Q9VHT2 Q9VHT2 tex PTHR22839:SF0 THO COMPLEX SUBUNIT 3 THO3 THO COMPLEX SUBUNIT 3 gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription export complex#GO:0000346;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0041248|UniProtKB=P83292 P83292 Gr23a PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038420|UniProtKB=Q9VEW3 Q9VEW3 dmCG10311 PTHR34609:SF17 GEO08273P1-RELATED MARVEL DOMAIN-CONTAINING PROTEIN 3 DROME|FlyBase=FBgn0027603|UniProtKB=Q9VWK5 Q9VWK5 Ulp1 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protease#PC00190 DROME|FlyBase=FBgn0020641|UniProtKB=P91939 P91939 Lcp65Ad PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0035189|UniProtKB=Q9W0J9 Q9W0J9 CT9987 PTHR13204:SF1 PTD012 PROTEIN BETA-KETO L-GULONATE DECARBOXYLASE catalytic activity#GO:0003824;zinc ion binding#GO:0008270;hydrolase activity, acting on ester bonds#GO:0016788;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;cation binding#GO:0043169 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0032003|UniProtKB=Q7KTJ2 Q7KTJ2 Dmel\CG8349 PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleoside catabolic process#GO:0009164;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 deaminase#PC00088 Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144 DROME|FlyBase=FBgn0034907|UniProtKB=Q9W1J5 Q9W1J5 Dmel\CG5539 PTHR12300:SF197 HVA22-LIKE PROTEINS LP05237P-RELATED tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840 cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;organelle membrane#GO:0031090 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0034703|UniProtKB=Q9W282 Q9W282 Dmel\CG3045 PTHR11142:SF5 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE(38_39) SYNTHASE catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;isomerase activity#GO:0016853 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA modification#GO:0016556;pseudouridine synthesis#GO:0001522;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144 DROME|FlyBase=FBgn0037686|UniProtKB=Q9VHE5 Q9VHE5 RpL34b PTHR10759:SF0 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 DROME|FlyBase=FBgn0003710|UniProtKB=P48613 P48613 tipE PTHR12335:SF6 TIPE PROTEIN TEMPERATURE-INDUCED PARALYTIC E PROTEIN TIPE transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of transport#GO:0051049;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0040291|UniProtKB=Q9NHX0 Q9NHX0 Roc1b PTHR11210:SF2 RING BOX E3 UBIQUITIN-PROTEIN LIGASE RBX1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0033208|UniProtKB=Q7JWG9 Q7JWG9 mRpL52 PTHR34090:SF1 39S RIBOSOMAL PROTEIN L52, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML52 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0052079|UniProtKB=Q9VTD5 Q9VTD5 CG11806 PTHR22950:SF340 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN-RELATED L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333 intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0024371|UniProtKB=O77051 O77051 E2f2 PTHR12081:SF18 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F2-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 p53 pathway feedback loops 2#P04398>E2F-1#P04652;Cell cycle#P00013>E2F#P00488;p53 pathway#P00059>E2F-1#P04627 DROME|FlyBase=FBgn0031692|UniProtKB=Q9VMT2 Q9VMT2 TpnC25D PTHR23050:SF221 CALCIUM BINDING PROTEIN FI07231P-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0003189|UniProtKB=P05990 P05990 r PTHR11405:SF5 CARBAMOYLTRANSFERASE FAMILY MEMBER MULTIFUNCTIONAL PROTEIN CAD catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;ligase activity#GO:0016874;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;hydrolase activity#GO:0016787;ligase activity, forming carbon-nitrogen bonds#GO:0016879 pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 DROME|FlyBase=FBgn0035585|UniProtKB=Q9VZ72 Q9VZ72 ATPsynCF6L PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT F6, MITOCHONDRIAL protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;proton-transporting ATP synthase complex#GO:0045259;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0020508|UniProtKB=Q9VY19 Q9VY19 Ag5r2 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0085407|UniProtKB=Q9VM39 Q9VM39 Pvf3 PTHR21719:SF2 FI06402P-RELATED FI06402P-RELATED hemopoiesis#GO:0030097;cell development#GO:0048468;embryo development#GO:0009790;cell differentiation#GO:0030154;cell motility#GO:0048870;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108 DROME|FlyBase=FBgn0052476|UniProtKB=Q8SYV9 Q8SYV9 mthl14 PTHR46953:SF3 G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED G-PROTEIN COUPLED RECEPTOR MTH-LIKE 14-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0263112|UniProtKB=C3KGP2 C3KGP2 Mitf PTHR45776:SF2 MIP04163P MIP04163P sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0035333|UniProtKB=Q9W023 Q9W023 Dmel\CG1317 PTHR13145:SF0 SSM4 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MARCHF6 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;response to stimulus#GO:0050896 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0265487|UniProtKB=O16011 O16011 mbl PTHR12675:SF12 MUSCLEBLIND-LIKE PROTEIN PROTEIN MUSCLEBLIND nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0034634|UniProtKB=Q9W2G2 Q9W2G2 Dmel\CG10494 PTHR43599:SF13 MULTIFUNCTIONAL PROTEIN ADE2 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0085346|UniProtKB=A8JRG8 A8JRG8 Rpp14a PTHR15441:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P14 RIBONUCLEASE P PROTEIN SUBUNIT P14 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;endonuclease complex#GO:1905348;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 endoribonuclease#PC00094 DROME|FlyBase=FBgn0027339|UniProtKB=M9PGG2 M9PGG2 jim PTHR24384:SF189 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0037739|UniProtKB=Q9VH82 Q9VH82 Dmel\CG12948 PTHR16260:SF3 SIMILAR TO 1700123O20RIK PROTEIN SIMILAR TO 1700123O20RIK PROTEIN-RELATED DROME|FlyBase=FBgn0260399|UniProtKB=Q95TN8 Q95TN8 gwl PTHR24356:SF438 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE GREATWALL transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0040391|UniProtKB=Q9W4Z5 Q9W4Z5 Dmel\CG2854 PTHR31596:SF1 T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0053093|UniProtKB=Q86B82 Q86B82 CG5340 PTHR10209:SF885 OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN FI07970P-RELATED metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034485|UniProtKB=Q7JXU8 Q7JXU8 CT31033 PTHR16083:SF85 LEUCINE RICH REPEAT CONTAINING PROTEIN RH62264P scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035244|UniProtKB=Q9W0C5 Q9W0C5 ABCB7 PTHR24221:SF402 ATP-BINDING CASSETTE SUB-FAMILY B IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0038332|UniProtKB=Q9VF71 Q9VF71 CG6136 PTHR12598:SF0 COPPER HOMEOSTASIS PROTEIN CUTC COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;copper ion binding#GO:0005507;transition metal ion binding#GO:0046914 primary active transporter#PC00068 DROME|FlyBase=FBgn0031749|UniProtKB=Q8T3P5 Q8T3P5 Dmel\CG14000 PTHR41152:SF8 AT26438P-RELATED AT26438P-RELATED DROME|FlyBase=FBgn0028397|UniProtKB=Q9VXJ9 Q9VXJ9 Tob PTHR17537:SF5 TRANSDUCER OF ERBB2 TOB TRANSDUCER OF ERBB2, ISOFORM A transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0045063|UniProtKB=Q8WSF3 Q8WSF3 fdl PTHR22600:SF3 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE FDL-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;extracellular region#GO:0005576 glycosidase#PC00110 DROME|FlyBase=FBgn0033980|UniProtKB=Q9V773 Q9V773 Cyp6a20 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0032398|UniProtKB=Q9VKC7 Q9VKC7 Dmel\CG6766 PTHR15414:SF0 OS-9-RELATED ENDOPLASMIC RETICULUM LECTIN 1 biological regulation#GO:0065007;macromolecule localization#GO:0033036;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;localization#GO:0051179;cell communication#GO:0007154;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;cellular localization#GO:0051641;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0028671|UniProtKB=Q9XZ10 Q9XZ10 Vha100-1 PTHR11629:SF114 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;enzyme binding#GO:0019899;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515 monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885 cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ATP synthase#PC00002 DROME|FlyBase=FBgn0039431|UniProtKB=Q9VBE5 Q9VBE5 plum PTHR11640:SF31 NEPHRIN MIP08606P protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0010602|UniProtKB=Q7KNM2 Q7KNM2 lwr PTHR24067:SF248 UBIQUITIN-CONJUGATING ENZYME E2 DORSAL INTERACTING PROTEIN 4 ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein sumoylation#GO:0016925;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0260964|UniProtKB=Q8IH57 Q8IH57 Vmat PTHR23506:SF45 GH10249P GH10249P symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:sodium symporter activity#GO:0015370;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;axon#GO:0030424;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;axon terminus#GO:0043679 transporter#PC00227;secondary carrier transporter#PC00258 5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424 DROME|FlyBase=FBgn0040106|UniProtKB=Q9VPS1 Q9VPS1 lectin-21Cb PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0023541|UniProtKB=O46051 O46051 Cyp4d14 PTHR24291:SF187 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4AE1-RELATED oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037574|UniProtKB=Q9VHS7 Q9VHS7 Coq2 PTHR11048:SF42 PRENYLTRANSFERASES 4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 cytoplasm#GO:0005737;plasma membrane#GO:0005886;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0004057|UniProtKB=P12646 P12646 G6pd PTHR23429:SF23 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;glucose-6-phosphate dehydrogenase activity#GO:0004345;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydrogenase#PC00092 DROME|FlyBase=FBgn0037900|UniProtKB=Q9VGN8 Q9VGN8 Dmel\CG5276 PTHR13023:SF3 APYRASE SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029 membrane#GO:0016020;cellular anatomical structure#GO:0110165 nucleotide phosphatase#PC00173;hydrolase#PC00121 DROME|FlyBase=FBgn0035490|UniProtKB=Q9VZJ2 Q9VZJ2 Dmel\CG1136 PTHR10380:SF206 CUTICLE PROTEIN GH27759P extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0031224|UniProtKB=Q9VPK4 Q9VPK4 dRbm7 PTHR13798:SF12 RNA BINDING MOTIF RBM PROTEIN -RELATED RNA BINDING MOTIF PROTEIN 11-RELATED RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039850|UniProtKB=Q9V9X3 Q9V9X3 Dmel\CG11333 PTHR14119:SF17 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0030863|UniProtKB=Q9VX25 Q9VX25 CG8188 PTHR24068:SF126 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 S ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 DROME|FlyBase=FBgn0051108|UniProtKB=Q9VBX5 Q9VBX5 TTLL5 PTHR12241:SF145 TUBULIN POLYGLUTAMYLASE TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 5 ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;tubulin binding#GO:0015631;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0039591|UniProtKB=Q9VAU4 Q9VAU4 Dmel\CG9988 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0053178|UniProtKB=X2JF29 X2JF29 CG5579 PTHR10689:SF6 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0010583|UniProtKB=Q8IPW2 Q8IPW2 dock PTHR19969:SF14 SH2-SH3 ADAPTOR PROTEIN-RELATED SH2_SH3 ADAPTER PROTEIN DREADLOCKS molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;protein-macromolecule adaptor activity#GO:0030674;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;signaling adaptor activity#GO:0035591 regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of macromolecule metabolic process#GO:0060255;ephrin receptor signaling pathway#GO:0048013;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of intrinsic apoptotic signaling pathway#GO:2001242;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of translation#GO:0045727;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of apoptotic signaling pathway#GO:2001233;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;post-transcriptional regulation of gene expression#GO:0010608;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036641|UniProtKB=Q9VV74 Q9VV74 Smn PTHR39267:SF1 SURVIVAL MOTOR NEURON-LIKE PROTEIN 1 SURVIVAL OF MOTOR NEURON DROME|FlyBase=FBgn0039560|UniProtKB=A0A0B4KHZ9 A0A0B4KHZ9 BOD1 PTHR31532:SF10 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 FAMILY MEMBER BIORIENTATION OF CHROMOSOMES IN CELL DIVISION PROTEIN 1-LIKE 1 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle lumen#GO:0043233;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0050362|UniProtKB=Q7JVN4 Q7JVN4 boly PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0264953|UniProtKB=M9MSG8 M9MSG8 Piezo PTHR13167:SF48 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 detection of mechanical stimulus#GO:0050982;response to external stimulus#GO:0009605;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;cellular response to abiotic stimulus#GO:0071214;response to mechanical stimulus#GO:0009612;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;biological regulation#GO:0065007;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0035473|UniProtKB=Q9VZL1 Q9VZL1 mge PTHR12504:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0023215|UniProtKB=M9NGP0 M9NGP0 Mnt PTHR11969:SF99 MAX DIMERIZATION, MAD MAX-BINDING PROTEIN MNT DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0028531|UniProtKB=Q9VJT3 Q9VJT3 BG:DS01068.11 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0033603|UniProtKB=A1Z8H7 A1Z8H7 Cpr47Ef PTHR10380:SF247 CUTICLE PROTEIN CUTICULAR PROTEIN 47EF, ISOFORM C extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0038536|UniProtKB=Q9VEG9 Q9VEG9 nrm PTHR31040:SF1 NURIM NURIM organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0023514|UniProtKB=Q9W550 Q9W550 i207 PTHR18763:SF0 WD-REPEAT PROTEIN 18 WD REPEAT-CONTAINING PROTEIN 18 DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;DNA-templated DNA replication#GO:0006261;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear pre-replicative complex#GO:0005656;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;pre-replicative complex#GO:0036387;endoribonuclease complex#GO:1902555;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DROME|FlyBase=FBgn0033423|UniProtKB=Q7K3X8 Q7K3X8 Alp6 PTHR11596:SF91 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0261290|UniProtKB=Q2MGK0 Q2MGK0 CheA84a PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0034689|UniProtKB=Q9W298 Q9W298 Dmel\CG2921 PTHR12260:SF6 DAMAGE-CONTROL PHOSPHATASE ARMT1 DAMAGE-CONTROL PHOSPHATASE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to stimulus#GO:0050896 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0260222|UniProtKB=E1JGR4 E1JGR4 Dmel\CG42496 PTHR21107:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0038145|UniProtKB=Q9VFV9 Q9VFV9 Droj2 PTHR43888:SF10 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ-LIKE-2, ISOFORM A molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671 biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;response to heat#GO:0009408;cellular response to heat#GO:0034605;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein refolding#GO:0042026;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0036285|UniProtKB=Q8T0M4 Q8T0M4 toe PTHR45636:SF56 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED EYEGONE, ISOFORM A-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0010194|UniProtKB=P28466 P28466 Wnt5 PTHR12027:SF77 WNT RELATED PROTEIN WNT-5 cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 DROME|FlyBase=FBgn0020389|UniProtKB=Q8IQV1 Q8IQV1 Papss PTHR11055:SF79 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE PAPS SYNTHETASE, ISOFORM D phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;sulfur compound metabolic process#GO:0006790;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 DROME|FlyBase=FBgn0026084|UniProtKB=O97428 O97428 cib PTHR20940:SF1 TETRA THYMOSIN CIBOULOT, ISOFORM A binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin monomer binding#GO:0003785;protein binding#GO:0005515 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0031649|UniProtKB=Q9VR48 Q9VR48 hoe2 PTHR43568:SF1 P PROTEIN CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0035675|UniProtKB=Q9VRT7 Q9VRT7 BcDNA:RE60135 PTHR20971:SF0 U6 SNRNA-ASSOCIATED PROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;Lsm2-8 complex#GO:0120115;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0038627|UniProtKB=Q9VE61 Q9VE61 CG7694 PTHR15710:SF243 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0027586|UniProtKB=Q9Y143 Q9Y143 Jhbp14 PTHR11008:SF18 PROTEIN TAKEOUT-LIKE PROTEIN BCDNA.GH05536-RELATED rhythmic process#GO:0048511;circadian rhythm#GO:0007623 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039694|UniProtKB=Q9VAH4 Q9VAH4 fig PTHR12320:SF98 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 DROME|FlyBase=FBgn0259149|UniProtKB=Q9W477 Q9W477 CG15768 PTHR11705:SF161 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI01817P-RELATED metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0020385|UniProtKB=O96553 O96553 pug PTHR48099:SF5 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 DROME|FlyBase=FBgn0038250|UniProtKB=Q8SX54 Q8SX54 Dmel\CG3505 PTHR24260:SF135 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED DROME|FlyBase=FBgn0033916|UniProtKB=Q7JW61 Q7JW61 Usp20-33 PTHR21646:SF86 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824 multicellular organism development#GO:0007275;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 cysteine protease#PC00081 DROME|FlyBase=FBgn0003975|UniProtKB=Q26366 Q26366 vg PTHR15950:SF15 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN PROTEIN VESTIGIAL-RELATED regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0051467|UniProtKB=Q8INL4 Q8INL4 CG6471 PTHR21055:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 phosphatase modulator#PC00184 DROME|FlyBase=FBgn0020496|UniProtKB=O46036 O46036 CtBP PTHR46029:SF7 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 DROME|FlyBase=FBgn0038217|UniProtKB=Q9VFL4 Q9VFL4 Dmel\CG14840 PTHR37161:SF2 HDC10475 AT11648P-RELATED DROME|FlyBase=FBgn0038431|UniProtKB=Q4V5J3 Q4V5J3 Dmel\CG10405 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0028372|UniProtKB=A0A0B4KFW5 A0A0B4KFW5 Kpc2 PTHR46738:SF1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 DROME|FlyBase=FBgn0004837|UniProtKB=P28159 P28159 Su(H) PTHR10665:SF0 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS SUPPRESSOR OF HAIRLESS PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Angiogenesis#P00005>CSL#P00233;Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Notch signaling pathway#P00045>Su(H)#P01101 DROME|FlyBase=FBgn0027575|UniProtKB=A0A0B4LHR4 A0A0B4LHR4 GABA-B-R2 PTHR10519:SF74 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cellular process#GO:0009987;regulation of biological process#GO:0050789 signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 DROME|FlyBase=FBgn0031254|UniProtKB=Q9VPP8 Q9VPP8 Dmel\CG13692 PTHR46688:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 DROME|FlyBase=FBgn0035557|UniProtKB=Q9VZA7 Q9VZA7 anon-WO0172774.162 PTHR11161:SF15 O-ACYLTRANSFERASE GH19286P-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0034735|UniProtKB=Q9W245 Q9W245 Dmel\CG4610 PTHR11806:SF4 GLUCOSE INHIBITED DIVISION PROTEIN A 5-TAURINOMETHYLURIDINE-[TRNA] SYNTHASE SUBUNIT MTO1, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;mitochondrial RNA modification#GO:1900864;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0015926|UniProtKB=Q24175 Q24175 dah PTHR12268:SF21 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DISCONTINUOUS ACTIN HEXAGON plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0033196|UniProtKB=Q7K1D7 Q7K1D7 HisT PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED CHOLINE_ETHANOLAMINE TRANSPORTER FLVCR1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;heme binding#GO:0020037;binding#GO:0005488;tetrapyrrole binding#GO:0046906 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;iron coordination entity transport#GO:1901678;metal ion transport#GO:0030001;nitrogen compound transport#GO:0071705 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0037700|UniProtKB=Q9VHC8 Q9VHC8 Dmel\CG8149 PTHR46551:SF1 SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0050081|UniProtKB=A1Z9Y5 A1Z9Y5 Ir51b PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0003137|UniProtKB=Q868Z9 Q868Z9 Ppn PTHR13723:SF322 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PAPILIN metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 DROME|FlyBase=FBgn0000542|UniProtKB=Q1W9P9 Q1W9P9 ec PTHR22975:SF9 UBIQUITIN SPECIFIC PROTEINASE ECHINUS SPLICE FORM 3 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0034904|UniProtKB=Q9W1J7 Q9W1J7 Dmel\CG15800 PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035384|UniProtKB=Q9VZW6 Q9VZW6 BcDNA:AT18037 PTHR22739:SF7 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED EG:152A3.3 PROTEIN-RELATED positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of Rho protein signal transduction#GO:0035023;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;positive regulation of signal transduction#GO:0009967;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0030859|UniProtKB=Q9VX29 Q9VX29 Dmel\CG12990 PTHR11161:SF15 O-ACYLTRANSFERASE GH19286P-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0036805|UniProtKB=Q95SH2 Q95SH2 Chmp1 PTHR10476:SF2 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1B-RELATED intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;macromolecule localization#GO:0033036;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;late endosome to vacuole transport#GO:0045324 vesicle membrane#GO:0012506;membrane#GO:0016020;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0039655|UniProtKB=Q8IML0 Q8IML0 Dmel\CG14507 PTHR11716:SF107 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 phospholipase#PC00186 DROME|FlyBase=FBgn0259152|UniProtKB=Q9VBX1 Q9VBX1 Clbn PTHR15239:SF6 NUCLEAR EXPORT MEDIATOR FACTOR NEMF RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF ribosomal large subunit binding#GO:0043023;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;tRNA binding#GO:0000049;protein-containing complex binding#GO:0044877;nucleic acid binding#GO:0003676;binding#GO:0005488 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;protein catabolic process#GO:0030163;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0063923|UniProtKB=O97042 O97042 Kaz1-ORFB PTHR21179:SF1 SERINE-TYPE ENDOPEPTIDASE INHIBITOR KAZ1-TYPE SERINE PROTEASE INHIBITOR-LIKE PROTEIN TYPE EPSILON-RELATED protease inhibitor#PC00191 DROME|FlyBase=FBgn0028878|UniProtKB=Q7KT79 Q7KT79 Dmel\CG15269 PTHR24384:SF189 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0052512|UniProtKB=Q9VRE4 Q9VRE4 CG15447 PTHR23241:SF102 LATE EMBRYOGENESIS ABUNDANT PLANTS LEA-RELATED LD23009P DROME|FlyBase=FBgn0027589|UniProtKB=Q7KMM5 Q7KMM5 BcDNA.GH04802 PTHR11003:SF358 POTASSIUM CHANNEL, SUBFAMILY K BCDNA.GH04802-RELATED transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0052279|UniProtKB=Q7YXH9 Q7YXH9 Drsl2 PTHR33147:SF98 DEFENSIN-LIKE PROTEIN 1 DRO1 PROTEIN-RELATED response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 antimicrobial response protein#PC00051 DROME|FlyBase=FBgn0000166|UniProtKB=P09081 P09081 bcd PTHR45664:SF22 PROTEIN ZERKNUELLT 1-RELATED HOMEOTIC PROTEIN BICOID-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0039937|UniProtKB=Q9V481 Q9V481 fd102C PTHR11829:SF416 FORKHEAD BOX PROTEIN FORKHEAD DOMAIN 102C sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0262018|UniProtKB=Q9VJB6 Q9VJB6 CadN2 PTHR24027:SF452 CADHERIN-23 NEURAL-CADHERIN 2-RELATED binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 DROME|FlyBase=FBgn0024183|UniProtKB=Q9V426 Q9V426 vig PTHR12299:SF17 HYALURONIC ACID-BINDING PROTEIN 4 AT19571P-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0036029|UniProtKB=Q9VT31 Q9VT31 Spef1b PTHR12509:SF9 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERM FLAGELLAR PROTEIN 1 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|Gene_ORFName=Dmel_CG46512|UniProtKB=A0ACD4DAZ1 A0ACD4DAZ1 CG46512 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0039033|UniProtKB=Q9VCS9 Q9VCS9 Or94a PTHR21137:SF37 ODORANT RECEPTOR ODORANT RECEPTOR 46A, ISOFORM B-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030605|UniProtKB=Q9VXZ0 Q9VXZ0 ND-B18 PTHR20900:SF0 NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 DROME|FlyBase=FBgn0031837|UniProtKB=Q4V3F0 Q4V3F0 DIP-iota PTHR12231:SF282 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN ETA, ISOFORM B-RELATED protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0263241|UniProtKB=Q8IQF1 Q8IQF1 Mocs1 PTHR22960:SF0 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;biosynthetic process#GO:0009058 DROME|FlyBase=FBgn0038763|UniProtKB=A0A0B4K6Q5 A0A0B4K6Q5 PIG-L PTHR12993:SF11 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity#GO:0003824;deacylase activity#GO:0160215;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 deacetylase#PC00087 DROME|FlyBase=FBgn0035228|UniProtKB=Q9W0E2 Q9W0E2 Dmel\CG12091 PTHR12320:SF98 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 DROME|FlyBase=FBgn0030323|UniProtKB=Q9VYV9 Q9VYV9 Vlet PTHR12333:SF0 COMM DOMAIN CONTAINING PROTEIN 10 COMM DOMAIN-CONTAINING PROTEIN 10 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0085413|UniProtKB=A8JQ65 A8JQ65 CG34384 PTHR11255:SF109 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 kinase#PC00137;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032924|UniProtKB=Q9VIF1 Q9VIF1 Nbr PTHR13620:SF133 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;catalytic activity, acting on DNA#GO:0140097;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 response to stimulus#GO:0050896;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;RNA metabolic process#GO:0016070;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA damage response#GO:0006974;DNA recombination#GO:0006310 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0030087|UniProtKB=Q9W391 Q9W391 CG7766 PTHR10749:SF7 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA-RELATED serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 DROME|FlyBase=FBgn0019650|UniProtKB=A0A6H2EG63 A0A6H2EG63 toy PTHR45636:SF54 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED TWIN OF EYELESS, ISOFORM D sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;head development#GO:0060322;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0031711|UniProtKB=Q9VMQ7 Q9VMQ7 Elp4 PTHR12896:SF1 PAX6 NEIGHBOR PROTEIN PAXNEB ELONGATOR COMPLEX PROTEIN 4 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;elongator holoenzyme complex#GO:0033588;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0014380|UniProtKB=Q24192 Q24192 RhoL PTHR24072:SF305 RHO FAMILY GTPASE RAS-LIKE GTP-BINDING PROTEIN RHOL ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell differentiation#GO:0030154;cell projection organization#GO:0030030;signaling#GO:0023052;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;Rac protein signal transduction#GO:0016601;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of developmental process#GO:0050793;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;cortical cytoskeleton organization#GO:0030865;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of locomotion#GO:0040012;axon guidance#GO:0007411;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0038680|UniProtKB=Q9VE01 Q9VE01 Cyp12a5 PTHR24305:SF238 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0036491|UniProtKB=Q9VUM6 Q9VUM6 Best4 PTHR10736:SF65 BESTROPHIN BESTROPHIN 1, ISOFORM C-RELATED monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0051216|UniProtKB=Q9VDU7 Q9VDU7 Naam PTHR11080:SF2 PYRAZINAMIDASE/NICOTINAMIDASE NICOTINAMIDASE amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 DROME|FlyBase=FBgn0263256|UniProtKB=M9PCI1 M9PCI1 Dmel\CG43394 PTHR16021:SF13 MANSC DOMAIN CONTAINING PROTEIN 1 EARTHBOUND 1-RELATED DROME|FlyBase=FBgn0087035|UniProtKB=Q9VUQ5 Q9VUQ5 AGO2 PTHR22891:SF66 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;single-stranded RNA binding#GO:0003727;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518 regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0263257|UniProtKB=M9NEI3 M9NEI3 Cngl PTHR45638:SF7 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED ION CHANNEL-LIKE, ISOFORM E ligand-gated ion channel#PC00141;ion channel#PC00133 DROME|FlyBase=FBgn0026063|UniProtKB=Q9VGQ0 Q9VGQ0 KP78b PTHR24346:SF114 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 3-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035011|UniProtKB=Q9W166 Q9W166 Dmel\CG13589 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0038008|UniProtKB=Q9VGB2 Q9VGB2 Dmel\CG3942 PTHR22958:SF43 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid metabolic process#GO:0006650;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0019624|UniProtKB=Q94514 Q94514 COX5A PTHR14200:SF11 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex IV#GO:0045277;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidase#PC00175;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0035851|UniProtKB=Q9VSF2 Q9VSF2 MED24 PTHR12898:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0011509|UniProtKB=Q9VSN9 Q9VSN9 SrpRbeta PTHR11485:SF34 TRANSFERRIN SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT BETA localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to ER#GO:0045047;establishment of protein localization#GO:0045184 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;rough endoplasmic reticulum#GO:0005791;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0037609|UniProtKB=Q9VHN5 Q9VHN5 Unc50 PTHR12841:SF6 PROTEIN UNC-50 HOMOLOG PROTEIN UNC-50 HOMOLOG intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 DROME|FlyBase=FBgn0265606|UniProtKB=Q24178 Q24178 Prosalpha4T1 PTHR11599:SF237 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7-1-RELATED ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0031698|UniProtKB=A8DYV5 A8DYV5 Ncoa6 PTHR34491:SF134 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 62 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0038205|UniProtKB=Q7KSK2 Q7KSK2 Kif19A PTHR24115:SF1016 KINESIN-RELATED KINESIN FAMILY MEMBER 19A protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0013726|UniProtKB=P40797 P40797 pnut PTHR18884:SF137 SEPTIN SEPTIN-7 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301 microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0033979|UniProtKB=P82711 P82711 Cyp6a19 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0030724|UniProtKB=Q9VXK0 Q9VXK0 Nipsnap PTHR21017:SF17 NIPSNAP-RELATED PROTEIN NIPSNAP DROME|FlyBase=FBgn0037737|UniProtKB=A8JQW3 A8JQW3 Pnn PTHR12707:SF0 PINN PININ catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039873|UniProtKB=Q9V9U1 Q9V9U1 Smvt PTHR42985:SF46 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER FI02923P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804 sodium ion transport#GO:0006814;transport#GO:0006810;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0042134|UniProtKB=Q9I7D3 Q9I7D3 Capr PTHR22922:SF20 GPI-ANCHORED PROTEIN P137 CAPRIN HOMOLOG RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032846|UniProtKB=Q9VIP2 Q9VIP2 Pyroxd1 PTHR43429:SF2 PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING TRNA LIGASE COMPLEX-ASSOCIATED NAD(P)H DEHYDROGENASE PYROXD1 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0250847|UniProtKB=Q0E8T1 Q0E8T1 anon-SAGE:Wang-122 PTHR11610:SF177 LIPASE IP13478P-RELATED catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0261477|UniProtKB=A1ZB86 A1ZB86 slim PTHR46428:SF1 KELCH DOMAIN-CONTAINING PROTEIN 10 KELCH DOMAIN-CONTAINING PROTEIN 10 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;positive regulation of MAPK cascade#GO:0043410 DROME|FlyBase=FBgn0034713|UniProtKB=Q9W272 Q9W272 Dmel\CG11291 PTHR19288:SF93 4-NITROPHENYLPHOSPHATASE-RELATED FI11325P-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0011638|UniProtKB=P40796 P40796 La PTHR22792:SF166 LUPUS LA PROTEIN-RELATED LUPUS LA PROTEIN HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035934|UniProtKB=Q7Z020 Q7Z020 TrpA1 PTHR24123:SF124 ANKYRIN REPEAT-CONTAINING TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY A MEMBER 1 ligand-gated monoatomic cation channel activity#GO:0099094;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085 system process#GO:0003008;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;transport#GO:0006810;sensory perception of chemical stimulus#GO:0007606;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;cellular process#GO:0009987;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;metal ion transport#GO:0030001;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;calcium ion transmembrane transport#GO:0070588;sensory perception of pain#GO:0019233 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0001222|UniProtKB=P22813 P22813 Hsf PTHR10015:SF427 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0035721|UniProtKB=Q9VRZ6 Q9VRZ6 Dmel\CG9948 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0015380|UniProtKB=Q27324 Q27324 drl PTHR24416:SF349 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE RYK protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0011582|UniProtKB=P41596 P41596 Dop1R1 PTHR24247:SF238 5-HYDROXYTRYPTAMINE RECEPTOR DOPAMINE RECEPTOR 1 neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 DROME|FlyBase=FBgn0263076|UniProtKB=A0A126GUN8 A0A126GUN8 Klp54D PTHR24115:SF418 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF12 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0033316|UniProtKB=Q9V4W1 Q9V4W1 Gle1 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 alcohol binding#GO:0043178;translation initiation factor binding#GO:0031369;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein binding#GO:0005515;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translation factor#PC00223 DROME|FlyBase=FBgn0035101|UniProtKB=A4IJ58 A4IJ58 p130CAS PTHR10654:SF18 CAS SCAFFOLDING PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 1 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell migration#GO:0016477;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0000307|UniProtKB=Q9NK54 Q9NK54 chif PTHR15375:SF26 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN CHIFFON kinase modulator#PC00140;kinase activator#PC00138 DROME|FlyBase=FBgn0010383|UniProtKB=Q95078 Q95078 Cyp18a1 PTHR24300:SF445 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 18A1 steroid hydroxylase activity#GO:0008395;binding#GO:0005488;tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 lipid metabolic process#GO:0006629;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0030456|UniProtKB=Q9VYG3 Q9VYG3 Dmel\CG4332 PTHR21347:SF0 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1L endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0000633|UniProtKB=A1Z9G5 A1Z9G5 tei PTHR11640:SF155 NEPHRIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0040918|UniProtKB=Q9W423 Q9W423 schlank PTHR12560:SF0 LONGEVITY ASSURANCE FACTOR 1 LAG1 LD18904P acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;ceramide metabolic process#GO:0006672 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032506|UniProtKB=Q9VJZ9 Q9VJZ9 Dmel\CG9395 PTHR21461:SF40 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN BETA-1,4-GALACTOSYLTRANSFERASE GALT-1 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0000108|UniProtKB=P14599 P14599 Appl PTHR23103:SF18 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID-BETA-LIKE PROTEIN cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039 neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995 protease inhibitor#PC00191 DROME|FlyBase=FBgn0085311|UniProtKB=Q9VE43 Q9VE43 CG7710 PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0052432|UniProtKB=Q9VPA1 Q9VPA1 CG13256 PTHR47537:SF3 CUBILIN GH12701P membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0037924|UniProtKB=Q9VGL0 Q9VGL0 Dmel\CG14712 PTHR23193:SF23 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP153 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0026058|UniProtKB=Q9VX20 Q9VX20 OdsH PTHR46799:SF3 HOMEOBOX PROTEIN UNC-4 HOMOLOG HOMEOBOX PROTEIN UNC-4 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0036504|UniProtKB=Q9VUP8 Q9VUP8 yellow-k PTHR10009:SF7 PROTEIN YELLOW-RELATED GH10609P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0250820|UniProtKB=Q9VDD7 Q9VDD7 meigo PTHR10778:SF10 SOLUTE CARRIER FAMILY 35 MEMBER B SOLUTE CARRIER FAMILY 35 MEMBER B1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;organophosphate ester transmembrane transporter activity#GO:0015605;UDP-galactose transmembrane transporter activity#GO:0005459;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nucleotide-sugar transmembrane transport#GO:0015780;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034959|UniProtKB=Q9W1D1 Q9W1D1 Xxylt PTHR46612:SF1 XYLOSIDE XYLOSYLTRANSFERASE 1 XYLOSIDE XYLOSYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 transferase#PC00220 DROME|FlyBase=FBgn0040396|UniProtKB=Q9U1K7 Q9U1K7 EG:140G11.5 PTHR12452:SF6 42-9-9 PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0010621|UniProtKB=Q7KKI0 Q7KKI0 CCT5 PTHR11353:SF94 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT EPSILON macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 DROME|FlyBase=FBgn0053531|UniProtKB=Q59DZ7 Q59DZ7 Ddr PTHR24416:SF634 TYROSINE-PROTEIN KINASE RECEPTOR DISCOIDIN DOMAIN RECEPTOR, ISOFORM F signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;binding#GO:0005488;collagen binding#GO:0005518;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0011739|UniProtKB=Q9VA38 Q9VA38 wts PTHR24356:SF447 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE WARTS protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 mitotic cell cycle phase transition#GO:0044772;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;regulation of developmental process#GO:0050793;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;regulation of apoptotic process#GO:0042981;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;positive regulation of apoptotic process#GO:0043065;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;hippo signaling#GO:0035329 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0062411|UniProtKB=Q9VA22 Q9VA22 Ctr1C PTHR12483:SF115 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS COPPER TRANSPORT PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transition metal ion transport#GO:0000041;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;copper ion transmembrane transport#GO:0035434;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0032175|UniProtKB=Q9VL48 Q9VL48 Dmel\CG13131 PTHR23202:SF130 WASP INTERACTING PROTEIN-RELATED MULTI SEX COMBS, ISOFORM A-RELATED nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0034132|UniProtKB=Q7K5K9 Q7K5K9 S-Lap8 PTHR11963:SF16 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0033788|UniProtKB=Q4V4H7 Q4V4H7 Dmel\CG13323 PTHR37685:SF1 GEO11136P1-RELATED GEO11136P1-RELATED DROME|FlyBase=FBgn0032350|UniProtKB=Q9VKI8 Q9VKI8 Phgdh PTHR42938:SF22 FORMATE DEHYDROGENASE 1 D-3-PHOSPHOGLYCERATE DEHYDROGENASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;oxidoreductase#PC00176 Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160 DROME|FlyBase=FBgn0037371|UniProtKB=Q8MSU4 Q8MSU4 Sym PTHR15245:SF20 SYMPLEKIN-RELATED SYMPLEKIN intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 DROME|FlyBase=FBgn0030756|UniProtKB=Q9VXF5 Q9VXF5 Dmel\CG9903 PTHR10361:SF70 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 primary active transporter#PC00068 DROME|FlyBase=FBgn0037698|UniProtKB=Q9VHD1 Q9VHD1 Dmel\CG16779 PTHR16089:SF40 REST COREPRESSOR COREST PROTEIN-RELATED SUPPRESSOR OF ACTIVATED EGL-4 PROTEIN 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0025679|UniProtKB=Q0IGQ2 Q0IGQ2 Klf15 PTHR23235:SF120 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUPPEL-LIKE FACTOR 15 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0031273|UniProtKB=Q9VPS3 Q9VPS3 Dmel\CG2839 PTHR22803:SF124 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED ACCESSORY GLAND PROTEIN ACP29AB-RELATED membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0039025|UniProtKB=Q9VCT9 Q9VCT9 Usp12-46 PTHR24006:SF733 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12_46 HOMOLOG deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0045478|UniProtKB=P83294 P83294 Gr64b PTHR21421:SF35 GUSTATORY RECEPTOR GUSTATORY RECEPTOR FOR SUGAR TASTE 64B-RELATED signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;molecular transducer activity#GO:0060089;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0034427|UniProtKB=A1ZBI7 A1ZBI7 Dmel\CG10474 PTHR10188:SF50 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034745|UniProtKB=Q9W235 Q9W235 tous PTHR32215:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 structural protein#PC00211 DROME|FlyBase=FBgn0004170|UniProtKB=P10084 P10084 sc PTHR13935:SF153 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE FAMILY BHLH TRANSCRIPTION FACTOR 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0010399|UniProtKB=Q24418 Q24418 Nmdar1 PTHR18966:SF377 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1 voltage-gated channel activity#GO:0022832;voltage-gated monoatomic ion channel activity#GO:0005244;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;dicarboxylic acid transmembrane transporter activity#GO:0005310;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NR1#P01010 DROME|FlyBase=FBgn0030457|UniProtKB=Q9VYG1 Q9VYG1 CG12096 PTHR13554:SF10 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5 protease#PC00190 DROME|FlyBase=FBgn0030321|UniProtKB=Q9VYW4 Q9VYW4 Dmel\CG1703 PTHR19211:SF14 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ATP binding#GO:0005524;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 translation elongation factor#PC00222 DROME|FlyBase=FBgn0000046|UniProtKB=P10981 P10981 Act87E PTHR11937:SF397 ACTIN ACTIN-57B-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 DROME|FlyBase=FBgn0050054|UniProtKB=Q0E9A7 Q0E9A7 Dmel\CG30054 PTHR10218:SF365 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA Q SUBUNIT-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552 heterotrimeric G-protein#PC00117;G-protein#PC00020 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Endothelin signaling pathway#P00019>Gq#P00586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Wnt signaling pathway#P00057>Galpha#P01451;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057 DROME|FlyBase=FBgn0036032|UniProtKB=Q9VT35 Q9VT35 Dmel\CG16711 PTHR13270:SF14 PROTEIN C20ORF116-RELATED SEX DETERMINATION AND DOSAGE COMPENSATION PROTEIN SDC-2 DROME|FlyBase=FBgn0033767|UniProtKB=Q0E9A0 Q0E9A0 Dmel\CG13148 PTHR21654:SF84 FI21293P1 FI21293P1 DROME|FlyBase=FBgn0040929|UniProtKB=Q9W3D4 Q9W3D4 Dmel\CG12659 PTHR31200:SF1 INO80 COMPLEX SUBUNIT C INO80 COMPLEX SUBUNIT C cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785 DROME|FlyBase=FBgn0013770|UniProtKB=Q95029 Q95029 CtsL1 PTHR12411:SF917 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L, LIKE-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030093|UniProtKB=Q9W384 Q9W384 Bap111 PTHR46232:SF1 SMARCE1 REGULATOR OF CHROMATIN SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;binding#GO:0005488 negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 DROME|FlyBase=FBgn0052568|UniProtKB=Q9VXB7 Q9VXB7 Dmel\CG32568 PTHR10257:SF3 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B WELL-ROUNDED, ISOFORM B enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 DROME|FlyBase=FBgn0033942|UniProtKB=Q7JZW0 Q7JZW0 Cpr51A PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0261266|UniProtKB=Q9VKD7 Q9VKD7 zuc PTHR43856:SF3 CARDIOLIPIN HYDROLASE MITOCHONDRIAL CARDIOLIPIN HYDROLASE endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity, acting on a nucleic acid#GO:0140640;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;lipase activity#GO:0016298 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;oogenesis#GO:0048477;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;nucleobase-containing compound biosynthetic process#GO:0034654;cell cycle#GO:0007049;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;germ cell development#GO:0007281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 phospholipase#PC00186 DROME|FlyBase=FBgn0052085|UniProtKB=Q9VTL8 Q9VTL8 Dmel\CG32085 PTHR13318:SF292 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6, ISOFORM A-RELATED proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0034663|UniProtKB=Q9W2C5 Q9W2C5 CT14230 PTHR21721:SF26 GH09876P-RELATED DUF753 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0039703|UniProtKB=Q9VAG3 Q9VAG3 Dmel\CG7829 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0028497|UniProtKB=Q8MLR7 Q8MLR7 Mtmr6 PTHR10807:SF134 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629 membrane#GO:0016020;cellular anatomical structure#GO:0110165 phosphatase#PC00181 DROME|FlyBase=FBgn0027550|UniProtKB=Q9Y110 Q9Y110 GH10711 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 DROME|FlyBase=FBgn0026378|UniProtKB=Q9V8W3 Q9V8W3 Rep PTHR11787:SF4 RAB GDP-DISSOCIATION INHIBITOR CHM, RAB ESCORT PROTEIN 1 protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;transport#GO:0006810 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0030719|UniProtKB=Q9VXK6 Q9VXK6 eIF5 PTHR23001:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 5 translation factor activity#GO:0180051;GTPase regulator activity#GO:0030695;translation initiation factor binding#GO:0031369;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;binding#GO:0005488;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0020647|UniProtKB=Q9VCE7 Q9VCE7 Pacs PTHR13280:SF17 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN KRUEPPEL TARGET AT 95D, ISOFORM A macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;localization within membrane#GO:0051668;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104 DROME|FlyBase=FBgn0038098|UniProtKB=Q9VG15 Q9VG15 CT22687 PTHR39069:SF8 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A FI17111P1 DROME|FlyBase=FBgn0028841|UniProtKB=Q9VJK8 Q9VJK8 jhamt PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 methyltransferase#PC00155;transferase#PC00220 DROME|FlyBase=FBgn0263346|UniProtKB=Q0KIC3 Q0KIC3 CG43427 PTHR13037:SF24 FORMIN POLYCOMB PROTEIN PCL-RELATED DROME|FlyBase=FBgn0033996|UniProtKB=Q7K490 Q7K490 Dmel\CG11807 PTHR15454:SF35 NISCHARIN RELATED NISCHARIN response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;Rac protein signal transduction#GO:0016601;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036778|UniProtKB=Q9VVN6 Q9VVN6 Cyp312a1 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0020261|UniProtKB=E1JJR3 E1JJR3 pcm PTHR12341:SF7 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 1 exonuclease activity#GO:0004527;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;RNA binding#GO:0003723;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 exoribonuclease#PC00099;RNA metabolism protein#PC00031 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 DROME|FlyBase=FBgn0266521|UniProtKB=M9NEA1 M9NEA1 stai PTHR10104:SF1 STATHMIN STATHMIN, ISOFORM D protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule depolymerization#GO:0007019;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular component disassembly#GO:0022411;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;microtubule polymerization or depolymerization#GO:0031109;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;protein depolymerization#GO:0051261;plasma membrane bounded cell projection organization#GO:0120036;regulation of microtubule-based process#GO:0032886;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;supramolecular fiber organization#GO:0097435;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;protein-containing complex disassembly#GO:0032984 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0036451|UniProtKB=Q9VUH9 Q9VUH9 Helz PTHR10887:SF365 DNA2/NAM7 HELICASE FAMILY ATP-DEPENDENT RNA HELICASE WITH ZINC FINGER DOMAIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 cytosol#GO:0005829;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P granule#GO:0043186 RNA helicase#PC00032 DROME|FlyBase=FBgn0041236|UniProtKB=P58985 P58985 Gr59d PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell body#GO:0044297;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0001248|UniProtKB=B7Z0E0 B7Z0E0 Idh PTHR11822:SF44 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;peroxisome#GO:0005777;microbody#GO:0042579;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036147|UniProtKB=Q9VTH0 Q9VTH0 Plod PTHR10730:SF45 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035104|UniProtKB=Q9W0U4 Q9W0U4 Dmel\CG13875 PTHR15286:SF1 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN FI07216P scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032913|UniProtKB=Q9VIG3 Q9VIG3 Dmel\CG9259 PTHR11012:SF48 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0027287|UniProtKB=A0A4D6K5M0 A0A4D6K5M0 Gmap PTHR18921:SF2 MYOSIN HEAVY CHAIN - RELATED THYROID RECEPTOR-INTERACTING PROTEIN 11 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi organization#GO:0007030;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 actin or actin-binding cytoskeletal protein#PC00041;actin binding motor protein#PC00040 DROME|FlyBase=FBgn0036502|UniProtKB=Q9VUP0 Q9VUP0 Dmel\CG7841 PTHR48614:SF2 AT03386P AT03386P DROME|FlyBase=FBgn0053156|UniProtKB=A1Z9F4 A1Z9F4 Nadk1b PTHR20275:SF44 NAD KINASE NAD KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172 DROME|FlyBase=FBgn0028496|UniProtKB=A1ZB93 A1ZB93 BcDNA:GH04922 PTHR19871:SF28 BETA TRANSDUCIN-RELATED PROTEIN AAA+ ATPASE DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0034564|UniProtKB=Q9W2P5 Q9W2P5 Dmel\CG9344 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 membrane-enclosed lumen#GO:0031974;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;U6 snRNP#GO:0005688;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;P-body#GO:0000932;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0283471|UniProtKB=P36188 P36188 wupA PTHR13738:SF43 TROPONIN I TROPONIN I cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 system process#GO:0003008;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;muscle contraction#GO:0006936 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;contractile muscle fiber#GO:0043292;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0040513|UniProtKB=Q9V4L4 Q9V4L4 kappaB-Ras PTHR46152:SF3 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 DROME|FlyBase=FBgn0086346|UniProtKB=Q9VB05 Q9VB05 ALiX PTHR23030:SF39 PCD6 INTERACTING PROTEIN-RELATED PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytokinesis#GO:0000910;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;cytoskeleton-dependent cytokinesis#GO:0061640;protein transport#GO:0015031;cell cycle process#GO:0022402;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;protein localization to organelle#GO:0033365;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0036587|UniProtKB=Q9VV09 Q9VV09 CT15890 PTHR45617:SF166 LEUCINE RICH REPEAT FAMILY PROTEIN LRRNT DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0025808|UniProtKB=O96532 O96532 Rad17 PTHR12172:SF5 CELL CYCLE CHECKPOINT PROTEIN RAD17 CELL CYCLE CHECKPOINT PROTEIN RAD17 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;chromatin-protein adaptor activity#GO:0140463 macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;DNA replication checkpoint signaling#GO:0000076;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic DNA replication checkpoint signaling#GO:0033314 chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, telomeric repeat region#GO:0140445;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;chromatin#GO:0000785;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0083965|UniProtKB=Q9VBG5 Q9VBG5 Dmel\CG34129 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0038866|UniProtKB=Q9VDD4 Q9VDD4 Dmel\CG5810 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0031392|UniProtKB=Q9VQ79 Q9VQ79 AIF PTHR43557:SF4 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL oxidoreductase activity, acting on NAD(P)H#GO:0016651;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839;mitochondrial protein import pathway#GO:7770058 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Apoptosis signaling pathway#P00006>AIF#P00286 DROME|FlyBase=FBgn0026417|UniProtKB=Q9VN60 Q9VN60 Hus1-like PTHR12900:SF0 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;telomere maintenance#GO:0000723;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic DNA damage checkpoint signaling#GO:0044773;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;DNA recombination#GO:0006310;metabolic process#GO:0008152;double-strand break repair#GO:0006302;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic DNA replication checkpoint signaling#GO:0033314;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;signaling#GO:0023052;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;sexual reproduction#GO:0019953;telomere organization#GO:0032200;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;negative regulation of cell cycle G2/M phase transition#GO:1902750;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0015039|UniProtKB=Q9V4I1 Q9V4I1 Cyp9b2 PTHR24292:SF54 CYTOCHROME P450 CYTOCHROME P450 9B1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0036808|UniProtKB=Q9VVS1 Q9VVS1 Dic4 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310 inorganic anion transport#GO:0015698;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;C4-dicarboxylate transport#GO:0015740;phosphate ion transport#GO:0006817;dicarboxylic acid transport#GO:0006835;carboxylic acid transmembrane transport#GO:1905039;succinate transport#GO:0015744;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0040351|UniProtKB=Q8SYN0 Q8SYN0 EG:BACR7A4.12 PTHR23050:SF548 CALCIUM BINDING PROTEIN RE52086P molecular function regulator activity#GO:0098772;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;cation binding#GO:0043169 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0051159|UniProtKB=Q9VCX4 Q9VCX4 mRRF2 PTHR43261:SF9 TRANSLATION ELONGATION FACTOR G-RELATED RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467;translation#GO:0006412;mitochondrial gene expression#GO:0140053;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307 translation elongation factor#PC00222;translation factor#PC00223;translational protein#PC00263 DROME|FlyBase=FBgn0012034|UniProtKB=Q9VP61 Q9VP61 AcCoAS PTHR24095:SF244 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 DROME|FlyBase=FBgn0030329|UniProtKB=Q9VYV3 Q9VYV3 prtp PTHR45672:SF3 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 DROME|FlyBase=FBgn0032726|UniProtKB=Q9VJ32 Q9VJ32 Dmel\CG10621 PTHR46015:SF1 ZGC:172121 BETAINE-HOMOCYSTEINE S-METHYLTRANSFERASE-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038 Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024 DROME|FlyBase=FBgn0035006|UniProtKB=Q9W171 Q9W171 Dmel\CG4563 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;nucleobase-containing compound biosynthetic process#GO:0034654;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 ligase#PC00142 DROME|FlyBase=FBgn0032956|UniProtKB=Q9V9R2 Q9V9R2 Cul2 PTHR11932:SF174 CULLIN CULLIN-2 protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378 catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein modification by small protein conjugation or removal#GO:0070647;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0010043|UniProtKB=Q9VG93 Q9VG93 GstD7 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0045468|UniProtKB=Q8IN22 Q8IN22 Gr93d PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0259190|UniProtKB=B7Z0Y1 B7Z0Y1 Ir7d PTHR42643:SF52 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 11A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0040509|UniProtKB=Q9VK52 Q9VK52 ACXB PTHR45627:SF12 ADENYLATE CYCLASE TYPE 1 ADENYLYL CYCLASE X E-RELATED adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0051924|UniProtKB=Q8MZ65 Q8MZ65 CG5564 PTHR18901:SF48 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 DROME|FlyBase=FBgn0087013|UniProtKB=Q9VN44 Q9VN44 Karybeta3 PTHR10527:SF5 IMPORTIN BETA IMPORTIN-5 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 DROME|FlyBase=FBgn0032178|UniProtKB=Q9VL44 Q9VL44 Spn31A PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0264560|UniProtKB=A1Z8W8 A1Z8W8 garz PTHR10663:SF412 GUANYL-NUCLEOTIDE EXCHANGE FACTOR GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi cis cisterna#GO:0000137;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi cisterna#GO:0031985;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0036294|UniProtKB=M9PFA9 M9PFA9 Dmel\CG10654 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0036829|UniProtKB=Q9VVU7 Q9VVU7 Ir75d PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007 postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 DROME|FlyBase=FBgn0031645|UniProtKB=Q9VR44 Q9VR44 CT10168 PTHR11662:SF411 SOLUTE CARRIER FAMILY 17 GH05102P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0001170|UniProtKB=P10035 P10035 H2.0 PTHR46808:SF1 H2.0-LIKE HOMEOBOX PROTEIN H2.0-LIKE HOMEOBOX PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0038475|UniProtKB=Q7KSF5 Q7KSF5 Keap1 PTHR24412:SF451 KELCH PROTEIN FI11917P enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030966|UniProtKB=Q9VWP4 Q9VWP4 shop PTHR19372:SF7 SULFITE REDUCTASE SULFITE OXIDASE, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198 DROME|FlyBase=FBgn0260462|UniProtKB=Q9VN93 Q9VN93 CtsF PTHR12411:SF1051 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN F peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0028999|UniProtKB=Q9V3B8 Q9V3B8 nerfin-1 PTHR15065:SF4 INSULINOMA-ASSOCIATED 1 LD18634P DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565 multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;nervous system development#GO:0007399;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of cell cycle#GO:0051726;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038280|UniProtKB=Q9VFE1 Q9VFE1 Dmel\CG14861 PTHR13025:SF6 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 DROME|FlyBase=FBgn0263131|UniProtKB=A8JNU1 A8JNU1 CG12436 PTHR45627:SF16 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 DROME|FlyBase=FBgn0030459|UniProtKB=Q7Z2C5 Q7Z2C5 Dmel\CG12723 PTHR10068:SF14 BONE MARROW PROTEOGLYCAN ESX-1 SECRETION-ASSOCIATED PROTEIN ESPK extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0011204|UniProtKB=Q95RU0 Q95RU0 cue PTHR46513:SF42 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED PROTEIN CUEBALL transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0039078|UniProtKB=Q9VCM2 Q9VCM2 Dmel\CG4374 PTHR24393:SF138 ZINC FINGER PROTEIN IP01201P-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0037293|UniProtKB=Q9VN77 Q9VN77 RabGGTa PTHR11129:SF2 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity, acting on a protein#GO:0140096 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0025469|UniProtKB=Q7JVE7 Q7JVE7 slv PTHR10791:SF112 RAG1-ACTIVATING PROTEIN 1 SUGAR TRANSPORTER SWEET1 sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0032157|UniProtKB=Q9VL72 Q9VL72 Etl1 PTHR10799:SF964 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD_H BOX 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;heterochromatin formation#GO:0031507;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0260386|UniProtKB=A0A0C4DHF5 A0A0C4DHF5 mtg PTHR22933:SF32 FI18007P1-RELATED MIND THE GAP, ISOFORM E DROME|FlyBase=FBgn0028475|UniProtKB=Q9V415 Q9V415 Hrd3 PTHR11102:SF147 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 1 catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0013987|UniProtKB=P49071 P49071 MAPk-Ak2 PTHR24349:SF561 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;kinase binding#GO:0019900;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;calmodulin binding#GO:0005516;transferase activity#GO:0016740;kinase activity#GO:0016301;mitogen-activated protein kinase binding#GO:0051019;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Angiogenesis#P00005>MAPKAPK2/3#P00244;Ras Pathway#P04393>MAPKAP#P04564;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;PDGF signaling pathway#P00047>MAPKAPK2#P01157 DROME|FlyBase=FBgn0030720|UniProtKB=Q9VXK5 Q9VXK5 dSpb1 PTHR10920:SF13 RIBOSOMAL RNA METHYLTRANSFERASE PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3 RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a rRNA#GO:0140102;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;methylation#GO:0032259;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0052736|UniProtKB=Q9W3T5 Q9W3T5 sloth1 PTHR35250:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 4 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 5 DROME|FlyBase=FBgn0038436|UniProtKB=Q9VEU5 Q9VEU5 Gyc89Db PTHR45655:SF5 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 SOLUBLE GUANYLATE CYCLASE 89DA-RELATED catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829;guanylate cyclase activity#GO:0004383 response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;catalytic complex#GO:1902494 cyclase#PC00079;guanylate cyclase#PC00114 DROME|FlyBase=FBgn0031216|UniProtKB=Q9VPI9 Q9VPI9 Zir PTHR23317:SF76 DEDICATOR OF CYTOKINESIS DOCK LD20667P guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0032095|UniProtKB=Q9VLE6 Q9VLE6 Toll-4 PTHR24365:SF555 TOLL-LIKE RECEPTOR MSTPROX-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0002719|UniProtKB=Q9VG31 Q9VG31 Men PTHR23406:SF80 MALIC ENZYME-RELATED GH17657P-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176 DROME|FlyBase=FBgn0020908|UniProtKB=Q8MSI2 Q8MSI2 Scp1 PTHR10827:SF93 RETICULOCALBIN GH15296P metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0023395|UniProtKB=O16102 O16102 Chd3 PTHR45623:SF9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD3 ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0051358|UniProtKB=Q9VGD9 Q9VGD9 CG17424 PTHR10264:SF137 BAND 7 PROTEIN-RELATED GH04404P1 transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0051872|UniProtKB=Q9VKT1 Q9VKT1 CG17093 PTHR11005:SF144 LYSOSOMAL ACID LIPASE-RELATED AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0004390|UniProtKB=P48423 P48423 RasGAP1 PTHR10194:SF148 RAS GTPASE-ACTIVATING PROTEINS GTPASE-ACTIVATING PROTEIN GTPase-activating protein#PC00257 FGF signaling pathway#P00021>RasGAP#P00646;PDGF signaling pathway#P00047>RasGAP#P01152;EGF receptor signaling pathway#P00018>GAP#P00546 DROME|FlyBase=FBgn0085399|UniProtKB=A8DYL2 A8DYL2 CG13498 PTHR47537:SF1 CUBILIN CUB DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0283472|UniProtKB=Q94533 Q94533 S6k PTHR24351:SF230 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;TORC1 signaling#GO:0038202;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;p53 pathway by glucose deprivation#P04397>S6K#P04636;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 DROME|FlyBase=FBgn0014018|UniProtKB=Q94527 Q94527 Rel PTHR24169:SF30 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P110 SUBUNIT transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 intracellular signaling cassette#GO:0141124;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;defense response to symbiont#GO:0140546;non-canonical NF-kappaB signal transduction#GO:0038061;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;positive regulation of transcription by RNA polymerase II#GO:0045944;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;response to peptide#GO:1901652;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;response to other organism#GO:0051707;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;canonical NF-kappaB signal transduction#GO:0007249;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;positive regulation of RNA metabolic process#GO:0051254;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252 DROME|FlyBase=FBgn0085412|UniProtKB=A8JR01 A8JR01 kmr PTHR12752:SF9 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN KRAMER, ISOFORM I DROME|FlyBase=FBgn0029822|UniProtKB=Q9W458 Q9W458 Dmel\CG12236 PTHR23110:SF111 BTB DOMAIN TRANSCRIPTION FACTOR FI01104P regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0051267|UniProtKB=Q8INA0 Q8INA0 Dmel\CG31267 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035824|UniProtKB=Q9VSB8 Q9VSB8 Dmel\CG8281 PTHR21505:SF8 MADF DOMAIN-CONTAINING PROTEIN-RELATED DPT-YFP REPRESSOR BY OVEREXPRESSION, ISOFORM D-RELATED DROME|FlyBase=FBgn0052677|UniProtKB=Q9W2S5 Q9W2S5 X11Lbeta PTHR12345:SF16 SYNTENIN RELATED X11L, ISOFORM F-RELATED biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 cell junction#GO:0030054;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;dendritic spine#GO:0043197 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0261799|UniProtKB=Q9VV62 Q9VV62 dsx-c73A PTHR18898:SF8 NUCLEOPROTEIN TPR-RELATED NUCLEOPROTEIN TPR structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;regulation of microtubule-based process#GO:0032886;nucleocytoplasmic transport#GO:0006913;RNA localization#GO:0006403;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of spindle organization#GO:0090224;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;regulation of organelle assembly#GO:1902115;regulation of mitotic spindle organization#GO:0060236;cellular localization#GO:0051641;regulation of spindle assembly#GO:0090169;mRNA export from nucleus#GO:0006406;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitotic spindle assembly#GO:1901673;metabolic process#GO:0008152;gene expression#GO:0010467;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0027607|UniProtKB=Q7KNA0 Q7KNA0 CG8230 PTHR12895:SF9 DYMECLIN DYMECLIN cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 DROME|FlyBase=FBgn0036927|UniProtKB=Q9VW68 Q9VW68 Gabat PTHR43206:SF1 AMINOTRANSFERASE 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 Pyrimidine Metabolism#P02771>Aminotransferase#P03129;Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825;Gamma-aminobutyric acid synthesis#P04384>GABA aminotransferase#P04480 DROME|FlyBase=FBgn0029895|UniProtKB=Q9W3X0 Q9W3X0 Dmel\CG14441 PTHR12766:SF11 DEATH DOMAIN-ASSOCIATED PROTEIN 6 DAXX DAXX HISTONE-BINDING DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0040097|UniProtKB=Q6GV06 Q6GV06 lectin-30A PTHR22803:SF124 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED ACCESSORY GLAND PROTEIN ACP29AB-RELATED membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0034066|UniProtKB=A1ZA83 A1ZA83 EMC7 PTHR13605:SF4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 ENDOPLASMIC RETICULUM MEMBRANE PROTEIN COMPLEX SUBUNIT 7 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0030257|UniProtKB=Q9VZ41 Q9VZ41 SmydA-4 PTHR46455:SF8 SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0250821|UniProtKB=Q8T4B6 Q8T4B6 NEST:bs06h05 PTHR10264:SF133 BAND 7 PROTEIN-RELATED AT06885P-RELATED molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0015011|UniProtKB=P50245 P50245 AhcyL2 PTHR23420:SF31 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE-LIKE 1-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0036919|UniProtKB=Q9VW57 Q9VW57 Grasp65 PTHR12893:SF0 GOLGI REASSEMBLY STACKING PROTEIN GRASP GRASP65 Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0263741|UniProtKB=A0A0B4KFD9 A0A0B4KFD9 CG15226 PTHR48233:SF4 MUCIN 4B, ISOFORM B-RELATED MUCIN 4B, ISOFORM B-RELATED DROME|FlyBase=FBgn0052082|UniProtKB=Q8IQE6 Q8IQE6 IRSp53 PTHR14206:SF7 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 INSULIN RECEPTOR SUBSTRATE 53 KDA, ISOFORM A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;actin filament bundle assembly#GO:0051017;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0025885|UniProtKB=O97477 O97477 Inos PTHR11510:SF5 MYO-INOSITOL-1 PHOSPHATE SYNTHASE INOSITOL-3-PHOSPHATE SYNTHASE 1 catalytic activity#GO:0003824;isomerase activity#GO:0016853 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 isomerase#PC00135 DROME|FlyBase=FBgn0053462|UniProtKB=A1ZA42 A1ZA42 CG30086 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0031217|UniProtKB=Q9VPJ0 Q9VPJ0 Creld PTHR24034:SF148 EGF-LIKE DOMAIN-CONTAINING PROTEIN RE58433P cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0032967|UniProtKB=Q9V9P7 Q9V9P7 gi19527787 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED DROME|FlyBase=FBgn0030600|UniProtKB=Q9NB71 Q9NB71 hiw PTHR45943:SF1 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;neuron development#GO:0048666;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;axon development#GO:0061564;axon guidance#GO:0007411;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of growth#GO:0040008 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0037842|UniProtKB=Q9VGV9 Q9VGV9 Dmel\CG6567 PTHR10655:SF74 LYSOPHOSPHOLIPASE-RELATED LYSOPHOSPHOLIPASE-LIKE PROTEIN 1 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 negative regulation of transport#GO:0051051;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of vesicle-mediated transport#GO:0060627;regulation of establishment of protein localization#GO:0070201;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of transport#GO:0051049;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 lipase#PC00143;phospholipase#PC00186 DROME|FlyBase=FBgn0005631|UniProtKB=Q9W213 Q9W213 robo1 PTHR12231:SF279 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN ROUNDABOUT 1, ISOFORM A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;cell recognition#GO:0008037;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;main axon#GO:0044304;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection membrane#GO:0031253;axon#GO:0030424;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0034249|UniProtKB=A1ZAW3 A1ZAW3 RhoGAP54D PTHR14963:SF7 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 19 G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0038516|UniProtKB=Q9VEJ3 Q9VEJ3 P5cr-2 PTHR11645:SF0 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283 metabolite interconversion enzyme#PC00262;reductase#PC00198 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 DROME|FlyBase=FBgn0085433|UniProtKB=Q9VF73 Q9VF73 Dmel\CG34404 PTHR23347:SF6 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED FI17904P1 DROME|FlyBase=FBgn0034849|UniProtKB=Q9W1R8 Q9W1R8 Dmel\CG3500 PTHR13144:SF0 TEX261 PROTEIN PROTEIN TEX261 cargo receptor activity#GO:0038024 intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0259923|UniProtKB=Q0KHR7 Q0KHR7 Septin4 PTHR18884:SF130 SEPTIN SEPTIN hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;cytokinesis#GO:0000910;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;localization#GO:0051179;regulation of secretion#GO:0051046;cytoskeleton-dependent cytokinesis#GO:0061640;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104;regulation of transport#GO:0051049 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;cell cortex#GO:0005938;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;secretory vesicle#GO:0099503;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 DROME|FlyBase=FBgn0026376|UniProtKB=M9PCE9 M9PCE9 Rgl PTHR23113:SF312 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE, ISOFORM E guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0041242|UniProtKB=A1Z881 A1Z881 Gr47a PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0028968|UniProtKB=Q8I0G5 Q8I0G5 gammaCOP PTHR10261:SF0 COATOMER SUBUNIT GAMMA COATOMER SUBUNIT GAMMA-2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;COPI-coated vesicle#GO:0030137;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi-associated vesicle#GO:0005798;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0261984|UniProtKB=A8JR46 A8JR46 Ire1 PTHR13954:SF6 IRE1-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE tyrosine protein kinase receptor#PC00233;transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110 DROME|FlyBase=FBgn0004034|UniProtKB=P09957 P09957 y PTHR10009:SF14 PROTEIN YELLOW-RELATED PROTEIN YELLOW cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0038421|UniProtKB=Q9VEW2 Q9VEW2 CG17931 PTHR13596:SF20 SMALL EDRK-RICH FACTOR 1 SERF-LIKE PROTEIN-RELATED cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0035420|UniProtKB=Q9VZS7 Q9VZS7 hob PTHR15678:SF6 ANTIGEN MLAA-22-RELATED BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2 DROME|FlyBase=FBgn0037749|UniProtKB=Q9VH72 Q9VH72 BVR PTHR43355:SF2 FLAVIN REDUCTASE (NADPH) FLAVIN REDUCTASE (NADPH) oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198 DROME|FlyBase=FBgn0034173|UniProtKB=Q7JY07 Q7JY07 Gapdh3 PTHR10836:SF76 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 DROME|FlyBase=FBgn0003048|UniProtKB=P18490 P18490 pcx PTHR12372:SF8 PECANEX PROTEIN PECANEX cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0039475|UniProtKB=Q9VB89 Q9VB89 DmelL2 PTHR11610:SF178 LIPASE FI01825P-RELATED hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0030660|UniProtKB=Q9VXT0 Q9VXT0 Dmel\CG8097 PTHR16043:SF1 DALRD3 PROTEIN DALR ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;tRNA binding#GO:0000049;RNA binding#GO:0003723 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187 DROME|FlyBase=FBgn0263113|UniProtKB=A1ZAV1 A1ZAV1 Cc2d2a PTHR20837:SF0 CENTROSOMAL PROTEIN-RELATED COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 2A localization#GO:0051179;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;organelle assembly#GO:0070925;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cellular process#GO:0009987;cell projection assembly#GO:0030031 cilium#GO:0005929;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0044028|UniProtKB=Q9VUX3 Q9VUX3 Notum PTHR21562:SF122 NOTUM-RELATED PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM DROME|FlyBase=FBgn0030663|UniProtKB=Q9VXS6 Q9VXS6 Dmel\CG8117 PTHR11477:SF53 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN IP08861P-RELATED transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0046999|UniProtKB=Q8SY67 Q8SY67 BcDNA:RH62928 PTHR11195:SF13 DESTABILASE-RELATED LYSOZYME hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039684|UniProtKB=Q9VAI7 Q9VAI7 Obp99d PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0001089|UniProtKB=Q9VMJ5 Q9VMJ5 Gal PTHR23421:SF65 BETA-GALACTOSIDASE RELATED BETA GALACTOSIDASE, ISOFORM A hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052 galactosidase#PC00104;hydrolase#PC00121 DROME|FlyBase=FBgn0037003|UniProtKB=Q9VPE0 Q9VPE0 Dmel\CG18281 PTHR23504:SF1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 GH21943P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0035010|UniProtKB=A0A0B4KG01 A0A0B4KG01 CG 13579 PTHR24230:SF141 G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 8B signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039795|UniProtKB=Q9VA48 Q9VA48 Spn100A PTHR11461:SF292 SERINE PROTEASE INHIBITOR, SERPIN SERPIN 100A regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0002931|UniProtKB=Q9VPI8 Q9VPI8 net PTHR19290:SF102 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0051637|UniProtKB=Q9VMC3 Q9VMC3 Dmel\CG31637 PTHR10704:SF44 CARBOHYDRATE SULFOTRANSFERASE LD35051P-RELATED sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0034366|UniProtKB=Q7JY94 Q7JY94 Atg7 PTHR10953:SF3 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;Atg12 activating enzyme activity#GO:0019778;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874 mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;post-translational protein modification#GO:0043687;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;cellular component assembly#GO:0022607;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;process utilizing autophagic mechanism#GO:0061919;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular component organization#GO:0016043;protein modification by small protein conjugation#GO:0032446 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;phagophore assembly site#GO:0000407 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 DROME|FlyBase=FBgn0004795|UniProtKB=Q24573 Q24573 retn PTHR15348:SF0 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT PROTEIN DEAD RINGER nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0001280|UniProtKB=P20348 P20348 janA PTHR12258:SF5 JANUS-A/JANUS-B SEX-REGULATED PROTEIN JANUS-A-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0034894|UniProtKB=Q7KVH9 Q7KVH9 sigmar PTHR12757:SF1 TUMOR NECROSIS FACTOR INDUCED PROTEIN PROTEIN SALIVARY GLANDS MARRED regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033199|UniProtKB=Q7K4J7 Q7K4J7 ima PTHR20932:SF13 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN LD36653P DROME|FlyBase=FBgn0040985|UniProtKB=Q9VJG4 Q9VJG4 osi PTHR21024:SF0 GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1 negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0034267|UniProtKB=E1JGK3 E1JGK3 Dmel\CG4984 PTHR10671:SF82 EPITHELIAL MEMBRANE PROTEIN-RELATED FI18012P1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0035034|UniProtKB=Q9W139 Q9W139 anon-WO0140519.176 PTHR23055:SF190 CALCIUM BINDING PROTEINS AT17667P-RELATED calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 DROME|FlyBase=FBgn0037942|UniProtKB=Q8T4A5 Q8T4A5 Dmel\CG14721 PTHR13622:SF14 THIAMIN PYROPHOSPHOKINASE THIAMINE PYROPHOSPHOKINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 alcohol biosynthetic process#GO:0046165;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 kinase#PC00137;transferase#PC00220 Thiamin metabolism#P02780>Thiamine kinase#P03176 DROME|FlyBase=FBgn0038424|UniProtKB=Q9VEV7 Q9VEV7 Fntb PTHR11774:SF6 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0036000|UniProtKB=Q9VSZ6 Q9VSZ6 CG3434 PTHR46064:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0029522|UniProtKB=A8JUS8 A8JUS8 Dmel\CG13373 PTHR14365:SF2 APOPTOSIS REGULATORY PROTEIN SIVA GEO12726P1-RELATED positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;immune system process#GO:0002376;regulation of immune response#GO:0050776;cell communication#GO:0007154 DROME|FlyBase=FBgn0039601|UniProtKB=Q9VAT2 Q9VAT2 CG1523 PTHR14588:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 10 DDB1- AND CUL4-ASSOCIATED FACTOR 10 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 DROME|FlyBase=FBgn0051343|UniProtKB=Q8SWX4 Q8SWX4 CG5839 PTHR11533:SF290 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;primary metabolic process#GO:0044238;peptide catabolic process#GO:0043171;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0024366|UniProtKB=O46099 O46099 EG:8D8.2 PTHR22917:SF6 HEMOPEXIN DOMAIN-CONTAINING PROTEIN EG:8D8.2 PROTEIN-RELATED DROME|FlyBase=FBgn0261563|UniProtKB=Q8IP51 Q8IP51 wb PTHR10574:SF446 NETRIN/LAMININ-RELATED WING BLISTER, ISOFORM B extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 DROME|FlyBase=FBgn0037613|UniProtKB=Q9VHN1 Q9VHN1 Cks85A PTHR23415:SF48 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 2 kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;mitotic cell cycle phase transition#GO:0044772;cellular process#GO:0009987;cell cycle process#GO:0022402 transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030268|UniProtKB=Q960Z0 Q960Z0 Klp10A PTHR24115:SF0 KINESIN-RELATED FI21273P1-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0034520|UniProtKB=Q8MZ02 Q8MZ02 lms PTHR24339:SF30 HOMEOBOX PROTEIN EMX-RELATED LATERAL MUSCLES SCARCER, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0052250|UniProtKB=Q9VZD9 Q9VZD9 PMP34 PTHR45939:SF5 PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED PEROXISOMAL MEMBRANE PROTEIN PMP34 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0250848|UniProtKB=Q9V3U6 Q9V3U6 CtsK1 PTHR12411:SF1075 CYSTEINE PROTEASE FAMILY C1-RELATED COUNTING FACTOR ASSOCIATED PROTEIN D catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 DROME|FlyBase=FBgn0267001|UniProtKB=Q9VYN8 Q9VYN8 Ten-a PTHR11219:SF69 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-A protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0265574|UniProtKB=Q9W0R0 Q9W0R0 Cdc5 PTHR45885:SF6 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 mRNA metabolic process#GO:0016071;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974 DROME|FlyBase=FBgn0033685|UniProtKB=A1Z8T6 A1Z8T6 OSCP1 PTHR21439:SF0 OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN PROTEIN OSCP1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0031496|UniProtKB=Q9VQL0 Q9VQL0 Dmel\CG17258 PTHR22028:SF5 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 191 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902 DROME|FlyBase=FBgn0032908|UniProtKB=Q7KT22 Q7KT22 Dme_CG9270 PTHR24223:SF448 ATP-BINDING CASSETTE SUB-FAMILY C FI20146P1-RELATED transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0027106|UniProtKB=Q9V3W6 Q9V3W6 Inx7 PTHR11893:SF38 INNEXIN INNEXIN INX7 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell communication#GO:0007154;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to radiation#GO:0009314;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 gap junction#PC00105 DROME|FlyBase=FBgn0085404|UniProtKB=C6SUV4 C6SUV4 CG34375-RA PTHR10315:SF117 E3 UBIQUITIN PROTEIN LIGASE SIAH IP10571P catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433 DROME|FlyBase=FBgn0031460|UniProtKB=Q9VQG6 Q9VQG6 Dmel\CG15399 PTHR24073:SF128 DRAB5-RELATED RAB-LIKE PROTEIN 3 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 DROME|FlyBase=FBgn0003512|UniProtKB=P07664 P07664 Sry-delta PTHR24409:SF417 ZINC FINGER PROTEIN 142 SERENDIPITY LOCUS PROTEIN BETA-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0037540|UniProtKB=Q9VHX0 Q9VHX0 Pbp95 PTHR46621:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 nucleic acid biosynthetic process#GO:0141187;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;transcription by RNA polymerase III#GO:0006383;snRNA transcription#GO:0009301;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DROME|FlyBase=FBgn0003275|UniProtKB=Q24320 Q24320 Polr2F PTHR47227:SF5 DNA-DIRECTED RNA POLYMERASE SUBUNIT K DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription by RNA polymerase I#GO:0006360;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 DROME|FlyBase=FBgn0034878|UniProtKB=Q95RQ8 Q95RQ8 pita PTHR24390:SF278 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 772 double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0053127|UniProtKB=Q86B58 Q86B58 Dmel\CG33127 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0035998|UniProtKB=Q9VSZ4 Q9VSZ4 Dmel\CG3437 PTHR12436:SF38 80 KDA MCM3-ASSOCIATED PROTEIN SAC3 DOMAIN-CONTAINING PROTEIN 1 cell cycle process#GO:0022402;centrosome cycle#GO:0007098;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;cytoskeleton organization#GO:0007010;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metabolic process#GO:0008152;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;cell cycle#GO:0007049;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;organelle assembly#GO:0070925;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;spindle organization#GO:0007051;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;organelle#GO:0043226 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0261108|UniProtKB=Q9VHR6 Q9VHR6 Atg13 PTHR13430:SF4 AUTOPHAGY-RELATED PROTEIN 13 AUTOPHAGY-RELATED PROTEIN 13 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;cellular component organization#GO:0016043;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914 transferase complex#GO:1990234;phagophore assembly site#GO:0000407;protein kinase complex#GO:1902911;cytosol#GO:0005829;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;autophagosome#GO:0005776;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0034372|UniProtKB=Q7K0S5 Q7K0S5 amls PTHR23153:SF38 UBX-RELATED UBX DOMAIN-CONTAINING PROTEIN 6 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0052190|UniProtKB=Q9VVK7 Q9VVK7 NUCB1 PTHR19237:SF20 NUCLEOBINDIN NUCLEOBINDIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0034245|UniProtKB=Q500Y7 Q500Y7 UQCR-6.4 PTHR15420:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 6.4 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 10 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0086907|UniProtKB=P04657 P04657 Cyt-c-d PTHR11961:SF56 CYTOCHROME C CYTOCHROME C electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 DROME|FlyBase=FBgn0029679|UniProtKB=Q9W4P9 Q9W4P9 Dmel\CG2901 PTHR10783:SF127 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED LD30826P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;phosphate transmembrane transporter activity#GO:0005315;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804;efflux transmembrane transporter activity#GO:0015562 transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular process#GO:0009987;export from cell#GO:0140352;homeostatic process#GO:0042592;phosphate ion transport#GO:0006817 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0035584|UniProtKB=Q9VZ73 Q9VZ73 Dmel\CG17030 PTHR24068:SF116 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>UbcH8#P01223;Parkinson disease#P00049>UbcH7#P01224 DROME|FlyBase=FBgn0028570|UniProtKB=Q9VQA6 Q9VQA6 robl22E PTHR10779:SF17 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 1 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0261953|UniProtKB=M9PIH9 M9PIH9 TfAP-2 PTHR10812:SF17 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2, ISOFORM D DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0036343|UniProtKB=Q9VU47 Q9VU47 Dmel\CG14115 PTHR21398:SF22 AGAP007094-PA IP12060P-RELATED DROME|FlyBase=FBgn0038552|UniProtKB=Q9VEE9 Q9VEE9 Alg1 PTHR13036:SF0 BETA1,4 MANNOSYLTRANSFERASE CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0261260|UniProtKB=A8JTM7 A8JTM7 mgl PTHR22722:SF14 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED MEGALIN, ISOFORM A hormone binding#GO:0042562;binding#GO:0005488 transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 DROME|FlyBase=FBgn0005649|UniProtKB=Q8IMX4 Q8IMX4 Rox8 PTHR10352:SF83 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G FI04408P biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 DROME|FlyBase=FBgn0035499|UniProtKB=Q9VZI1 Q9VZI1 Chd64 PTHR47385:SF14 CALPONIN TRANSGELIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 DROME|FlyBase=FBgn0026015|UniProtKB=O96651 O96651 Top3beta PTHR11390:SF20 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-BETA-1 catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0031696|UniProtKB=Q9VMS5 Q9VMS5 Bub1 PTHR14030:SF29 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of mitotic metaphase/anaphase transition#GO:0030071;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;chromosome organization#GO:0051276;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;sister chromatid cohesion#GO:0007062;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;meiotic sister chromatid cohesion#GO:0051177;negative regulation of chromosome segregation#GO:0051985;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816 membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0035237|UniProtKB=Q9W0D3 Q9W0D3 Dmel\CG13917 PTHR22427:SF7 GH15728P GH15728P DROME|FlyBase=FBgn0011296|UniProtKB=P82147 P82147 l(2)efl PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE protein refolding#GO:0042026;protein metabolic process#GO:0019538;protein folding#GO:0006457;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;response to heat#GO:0009408 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 DROME|FlyBase=FBgn0039597|UniProtKB=Q9VAT8 Q9VAT8 Dmel\CG9997 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031312|UniProtKB=Q9VPX8 Q9VPX8 Tango14 PTHR21528:SF0 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100 endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0085337|UniProtKB=A0A1Z1CK50 A0A1Z1CK50 Dmel\CG34308 PTHR12313:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0026190|UniProtKB=Q9VA65 Q9VA65 PH4alphaMP PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;oxidoreductase complex#GO:1990204;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032601|UniProtKB=Q9VJI5 Q9VJI5 yellow-b PTHR10009:SF12 PROTEIN YELLOW-RELATED PROTEIN YELLOW cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0000370|UniProtKB=Q9VID3 Q9VID3 crc PTHR13044:SF14 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CRYPTOCEPHAL, ISOFORM A DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0026319|UniProtKB=Q9XYR0 Q9XYR0 Traf4 PTHR10131:SF164 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031887|UniProtKB=Q9VM44 Q9VM44 Ugt307A1 PTHR48043:SF145 EG:EG0003.4 PROTEIN-RELATED FI06409P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 DROME|FlyBase=FBgn0032365|UniProtKB=Q9VKG6 Q9VKG6 CG32953 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006 mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane contact site#GO:0044232;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0032362|UniProtKB=Q9VKG9 Q9VKG9 spz4 PTHR23199:SF5 NEUROTROPHIN 1-RELATED PROTEIN SPAETZLE 4 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 response to other organism#GO:0051707;nervous system development#GO:0007399;defense response to other organism#GO:0098542;multicellular organismal process#GO:0032501;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;anatomical structure formation involved in morphogenesis#GO:0048646;defense response#GO:0006952;multicellular organism development#GO:0007275;innate immune response#GO:0045087;developmental process#GO:0032502;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;central nervous system development#GO:0007417;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;system development#GO:0048731;anatomical structure development#GO:0048856;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0260474|UniProtKB=E1JH19 E1JH19 Dmel\CG30002 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0011286|UniProtKB=Q24498 Q24498 RyR PTHR13715:SF79 RYANODINE RECEPTOR AND IP3 RECEPTOR RYANODINE RECEPTOR ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;calcium ion transmembrane import into cytosol#GO:0097553;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;sarcoplasmic reticulum#GO:0016529 ion channel#PC00133;ligand-gated ion channel#PC00141 Metabotropic glutamate receptor group I pathway#P00041>IP3R#P01056;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441;Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434 DROME|FlyBase=FBgn0052847|UniProtKB=Q8IQM1 Q8IQM1 Dmel\CG32847 PTHR12313:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0039099|UniProtKB=Q9VCK1 Q9VCK1 GILT2 PTHR13234:SF73 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN 2-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0030878|UniProtKB=Q9VX08 Q9VX08 Dmel\CG6769 PTHR13182:SF8 ZINC FINGER PROTEIN 622 CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 cellular process#GO:0009987;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034602|UniProtKB=Q9W2J7 Q9W2J7 Lapsyn PTHR24366:SF168 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS GH22922P-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0032707|UniProtKB=Q9VJ55 Q9VJ55 Dmel\CG10348 PTHR24393:SF183 ZINC FINGER PROTEIN LD28458P-RELATED transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0030120|UniProtKB=Q8T3Y1 Q8T3Y1 Dmel\CG17440 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0030584|UniProtKB=Q8SXQ5 Q8SXQ5 Grx5 PTHR10293:SF16 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036126|UniProtKB=Q9VTE8 Q9VTE8 Irbp18 PTHR23334:SF69 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN GAMMA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0030056|UniProtKB=Q9W3C8 Q9W3C8 CAH3 PTHR18952:SF114 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 3, ISOFORM A hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0039368|UniProtKB=Q9VBM6 Q9VBM6 CG17196-PA PTHR22883:SF511 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;vesicle organization#GO:0016050;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;developmental maturation#GO:0021700 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0259113|UniProtKB=P26019 P26019 PolA1 PTHR45861:SF1 DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA POLYMERASE ALPHA CATALYTIC SUBUNIT transferase activity#GO:0016740;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;sequence-specific DNA binding#GO:0043565;DNA replication origin binding#GO:0003688;binding#GO:0005488;single-stranded DNA binding#GO:0003697;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-directed DNA polymerase activity#GO:0003887 cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 DNA replication#P00017>Pol alpha#P00531 DROME|FlyBase=FBgn0004636|UniProtKB=P08645 P08645 Rap1 PTHR24070:SF459 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP1 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;intracellular signaling cassette#GO:0141124;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of neurotransmitter transport#GO:0051588;cellular response to chemical stimulus#GO:0070887;regulation of secretion by cell#GO:1903530;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;response to stimulus#GO:0050896;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular response to nitrogen compound#GO:1901699;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157;response to nitrogen compound#GO:1901698;regulation of secretion#GO:0051046;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 DROME|FlyBase=FBgn0040074|UniProtKB=Q9VV36 Q9VV36 retinin PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0029079|UniProtKB=A1ZAW5 A1ZAW5 icln PTHR21399:SF0 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 DROME|FlyBase=FBgn0286213|UniProtKB=P80455 P80455 RpS12 PTHR11843:SF0 40S RIBOSOMAL PROTEIN S12 SMALL RIBOSOMAL SUBUNIT PROTEIN ES12 primary metabolic process#GO:0044238;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;ribonucleoprotein complex biogenesis#GO:0022613;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;translation#GO:0006412;ribosomal small subunit biogenesis#GO:0042274;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0086708|UniProtKB=A8JNS4 A8JNS4 stv PTHR12329:SF5 BCL2-ASSOCIATED ATHANOGENE STARVIN, ISOFORM E molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072 DROME|FlyBase=FBgn0000449|UniProtKB=Q9NGX9 Q9NGX9 dib PTHR24305:SF166 CYTOCHROME P450 CYTOCHROME P450 302A1, MITOCHONDRIAL-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0039435|UniProtKB=Q9VBE1 Q9VBE1 TwdlP PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053998|UniProtKB=Q6IG52 Q6IG52 BP1058 PTHR37685:SF1 GEO11136P1-RELATED GEO11136P1-RELATED DROME|FlyBase=FBgn0030692|UniProtKB=Q9VXP3 Q9VXP3 mRpS30 PTHR13014:SF3 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S30/P52 PRO-APOTOTIC PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML65 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0010041|UniProtKB=Q9VG95 Q9VG95 GstD5 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0034323|UniProtKB=A1ZB55 A1ZB55 Dmel\CG18537 PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0030480|UniProtKB=Q9VYD7 Q9VYD7 Tim9a PTHR13172:SF5 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9 protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;mitochondrial intermembrane space#GO:0005758;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0030700|UniProtKB=Q9VXN0 Q9VXN0 CG15914 PTHR13615:SF3 GLYCOSYLTRANSFERASE-LIKE 1 TRNA-QUEUOSINE ALPHA-MANNOSYLTRANSFERASE glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0015034|UniProtKB=Q9V4T5 Q9V4T5 Cyp4e1 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0004419|UniProtKB=P23128 P23128 me31B PTHR47960:SF17 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 ATP-DEPENDENT RNA HELICASE DDX6-RELATED mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;P-body assembly#GO:0033962;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cytoplasmic stress granule assembly#GO:0034063;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organelle assembly#GO:0070925;negative regulation of translation#GO:0017148;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0262357|UniProtKB=M9NE79 M9NE79 Dmel\CG43055 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0032086|UniProtKB=Q9VLF7 Q9VLF7 Dmel\CG17906 PTHR12242:SF49 OS02G0130600 PROTEIN-RELATED IP08657P-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0035574|UniProtKB=Q9VZ85 Q9VZ85 RhoGEF64C PTHR46006:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Rho protein signal transduction#GO:0035023;regulation of cell communication#GO:0010646 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0002573|UniProtKB=Q9N658 Q9N658 sens PTHR24390:SF159 ZINC FINGER PROTEIN GROWTH FACTOR INDEPENDENT 1 TRANSCRIPTIONAL REPRESSOR double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0031690|UniProtKB=Q9VMT4 Q9VMT4 Dmel\CG7742 PTHR16110:SF1 TBC1 DOMAIN FAMILY MEMBER 19 TBC1 DOMAIN FAMILY MEMBER 19 DROME|FlyBase=FBgn0036909|UniProtKB=Q9VW41 Q9VW41 Ccdc58 PTHR31905:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0033578|UniProtKB=A1Z8E9 A1Z8E9 BBS4 PTHR44186:SF1 FAMILY NOT NAMED BBSOME COMPLEX MEMBER BBS4 DROME|FlyBase=FBgn0042711|UniProtKB=Q9NFT9 Q9NFT9 Hexl PTHR19443:SF16 HEXOKINASE HEXOKINASE-2-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 DROME|FlyBase=FBgn0030518|UniProtKB=Q9VY93 Q9VY93 CG11134 PTHR10640:SF7 METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0035889|UniProtKB=Q95U58 Q95U58 mkg-p PTHR12271:SF66 POLY A POLYMERASE CID PAP -RELATED GH05885P transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098 positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 nucleotidyltransferase#PC00174 DROME|FlyBase=FBgn0033699|UniProtKB=Q0E9B6 Q0E9B6 RpS11 PTHR10744:SF9 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 DROME|FlyBase=FBgn0030876|UniProtKB=Q9VX10 Q9VX10 Srx PTHR21348:SF4 FAMILY NOT NAMED SULFIREDOXIN-1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209 cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DROME|FlyBase=FBgn0039648|UniProtKB=Q9VAN1 Q9VAN1 Dmel\CG14515 PTHR45828:SF40 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0037517|UniProtKB=Q8SYU5 Q8SYU5 Dmel\CG10086 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0033949|UniProtKB=Q5U1B0 Q5U1B0 Had2 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0050272|UniProtKB=Q8MMD6 Q8MMD6 MFS1 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0033686|UniProtKB=Q7K175 Q7K175 Hen1 PTHR21404:SF3 HEN1 SMALL RNA 2'-O-METHYLTRANSFERASE DROME|FlyBase=FBgn0264489|UniProtKB=M9PF57 M9PF57 CG8154 PTHR13037:SF24 FORMIN POLYCOMB PROTEIN PCL-RELATED DROME|FlyBase=FBgn0031516|UniProtKB=Q8MRL3 Q8MRL3 Dmel\CG9663 PTHR48041:SF133 ABC TRANSPORTER G FAMILY MEMBER 28 GH24286P primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0030995|UniProtKB=Q9VWK8 Q9VWK8 Dmel\CG7914 PTHR19370:SF184 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE-LIKE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;reductase#PC00198 DROME|FlyBase=FBgn0036291|UniProtKB=Q9VTY4 Q9VTY4 CG10681 PTHR13511:SF0 KXDL MOTIF-CONTAINING PROTEIN 1 KXDL MOTIF-CONTAINING PROTEIN 1 organelle localization#GO:0051640;lysosome localization#GO:0032418;localization#GO:0051179 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0000463|UniProtKB=P10041 P10041 Delta PTHR24044:SF420 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN-RELATED intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 DROME|FlyBase=FBgn0020306|UniProtKB=Q9NDJ2 Q9NDJ2 dom PTHR45685:SF1 HELICASE SRCAP-RELATED CHROMATIN REMODELING PROTEIN DOMINO ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 Wnt signaling pathway#P00057>SWI/SNF#P01435 DROME|FlyBase=FBgn0034471|UniProtKB=Q7K088 Q7K088 Obp56e PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0000320|UniProtKB=Q05201 Q05201 eya PTHR10190:SF16 EYES ABSENT PROTEIN PHOSPHATASE EYA phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;developmental process#GO:0032502;regulation of response to stress#GO:0080134;cellular developmental process#GO:0048869;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;positive regulation of DNA metabolic process#GO:0051054;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0002962|UniProtKB=P25724 P25724 nanos PTHR12887:SF11 NANOS PROTEIN PROTEIN NANOS RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 oogenesis#GO:0048477;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of translation#GO:0017148;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;negative regulation of protein metabolic process#GO:0051248;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0040071|UniProtKB=Q9VEX7 Q9VEX7 tara PTHR16277:SF7 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 RE12330P transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transcription cofactor#PC00217 DROME|FlyBase=FBgn0015010|UniProtKB=Q9VY18 Q9VY18 Ag5r PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0037822|UniProtKB=Q9VGY5 Q9VGY5 CG14683 PTHR11265:SF0 S-ADENOSYL-METHYLTRANSFERASE MRAW 12S RRNA N(4)-CYTIDINE METHYLTRANSFERASE METTL15 catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a rRNA#GO:0140102 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0000253|UniProtKB=P62152 P62152 Cam PTHR23050:SF552 CALCIUM BINDING PROTEIN AT16150P-RELATED molecular function regulator activity#GO:0098772;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 DROME|FlyBase=FBgn0027579|UniProtKB=Q9Y137 Q9Y137 mino PTHR12563:SF23 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE BCDNA.GH07066 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid metabolic process#GO:0006638 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037244|UniProtKB=B9A0N7 B9A0N7 Dmel\CG14647 PTHR14136:SF17 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 DROME|FlyBase=FBgn0036109|UniProtKB=Q9VTC7 Q9VTC7 Cpr67Fa2 PTHR10380:SF230 CUTICLE PROTEIN CUTICULAR PROTEIN 47EE-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0040670|UniProtKB=Q9VI60 Q9VI60 e(y)2b PTHR12514:SF1 ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;metabolic process#GO:0008152;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;nucleocytoplasmic transport#GO:0006913;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;nuclear transport#GO:0051169;regulation of DNA-templated transcription#GO:0006355;nucleic acid transport#GO:0050657;localization#GO:0051179;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;DUBm complex#GO:0071819;SAGA complex#GO:0000124;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0053516|UniProtKB=Q59E13 Q59E13 dpr3 PTHR23279:SF4 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 2, ISOFORM F-RELATED cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253 DROME|FlyBase=FBgn0283545|UniProtKB=O76908 O76908 vilya PTHR22663:SF17 RING FINGER PROTEIN NARYA-RELATED RING FINGER PROTEIN NARYA-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789 cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;cell cycle#GO:0007049;reproductive process#GO:0022414;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;homologous chromosome pairing at meiosis#GO:0007129;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794 DROME|FlyBase=FBgn0085409|UniProtKB=R9PY37 R9PY37 smal PTHR24543:SF291 MULTICOPPER OXIDASE-RELATED SMOKE ALARM, ISOFORM D oxidoreductase#PC00176 DROME|FlyBase=FBgn0034075|UniProtKB=A0A0B4KFS5 A0A0B4KFS5 Asph PTHR12366:SF29 ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE ASPARTYL BETA-HYDROXYLASE, ISOFORM L catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096 monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;calcium ion homeostasis#GO:0055074;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038269|UniProtKB=Q9VFF3 Q9VFF3 Rrp6 PTHR12124:SF47 POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED EXOSOME COMPLEX COMPONENT 10 DROME|FlyBase=FBgn0033440|UniProtKB=A1Z7Y4 A1Z7Y4 Dmel\CG10459 PTHR44156:SF23 SUPERNUMERARY LIMBS, ISOFORM B-RELATED SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN DROME|FlyBase=FBgn0035968|UniProtKB=Q9VSV1 Q9VSV1 Slc45-1 PTHR19432:SF35 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0037014|UniProtKB=Q9VPC7 Q9VPC7 Dmel\CG13251 PTHR22736:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 COILED-COIL DOMAIN CONTAINING 66 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874 DROME|FlyBase=FBgn0036571|UniProtKB=Q9VUY8 Q9VUY8 Strump PTHR15691:SF6 WASH COMPLEX SUBUNIT 5 WASH COMPLEX SUBUNIT 5 actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;endosome organization#GO:0007032;cellular component organization or biogenesis#GO:0071840;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;endomembrane system organization#GO:0010256;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;actin filament-based process#GO:0030029;regulation of cytoskeleton organization#GO:0051493;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;protein polymerization#GO:0051258;regulation of supramolecular fiber organization#GO:1902903;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0053340|UniProtKB=Q8IMW8 Q8IMW8 Dmel\CG33340 PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0035382|UniProtKB=Q9VZW8 Q9VZW8 Or63a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031854|UniProtKB=Q9VM91 Q9VM91 TTLL3A PTHR45870:SF11 TUBULIN MONOGLYCYLASE TTLL3 TUBULIN MONOGLYCYLASE TTLL3 ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;catalytic activity#GO:0003824 cell projection organization#GO:0030030;gamete generation#GO:0007276;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;developmental process involved in reproduction#GO:0003006;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729 DROME|FlyBase=FBgn0004049|UniProtKB=Q9VFU8 Q9VFU8 yrt PTHR23280:SF25 4.1 G PROTEIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0027538|UniProtKB=Q7KN92 Q7KN92 beta4GalNAcTA PTHR19300:SF66 BETA-1,4-GALACTOSYLTRANSFERASE BETA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE A galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0050010|UniProtKB=Q8MKL1 Q8MKL1 CG30010 PTHR31449:SF3 UPF0598 PROTEIN C8ORF82 UPF0598 PROTEIN C8ORF82 DROME|FlyBase=FBgn0032247|UniProtKB=Q9VKV9 Q9VKV9 MAP1B PTHR43330:SF28 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 DROME|FlyBase=FBgn0032224|UniProtKB=Q9VKY8 Q9VKY8 Sps2 PTHR10256:SF0 SELENIDE, WATER DIKINASE INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0001218|UniProtKB=P29844 P29844 Hsc70-3 PTHR19375:SF144 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;gene expression#GO:0010467;protein maturation#GO:0051604;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;protein folding#GO:0006457;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein refolding#GO:0042026;response to unfolded protein#GO:0006986;macromolecule biosynthetic process#GO:0009059;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154 membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;nucleus#GO:0005634;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 DROME|FlyBase=FBgn0036768|UniProtKB=Q9VVM4 Q9VVM4 Dmel\CG7402 PTHR10342:SF264 ARYLSULFATASE MIP05773P-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 DROME|FlyBase=FBgn0037238|UniProtKB=Q9VN12 Q9VN12 CG1090 PTHR10846:SF73 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER CG1090-RELATED antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0051102|UniProtKB=A0A0B4KGX8 A0A0B4KGX8 Dmel\CG31102 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0038839|UniProtKB=Q9VDH3 Q9VDH3 Ktl PTHR14499:SF148 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING GH08630P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0053775|UniProtKB=A1Z924 A1Z924 BP1034 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0050366|UniProtKB=Q6NLJ5 Q6NLJ5 swif PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0035608|UniProtKB=Q9VRL8 Q9VRL8 blanks PTHR46205:SF5 LOQUACIOUS, ISOFORM B BLANKS-RELATED double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;ribonucleoprotein complex#GO:1990904;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0083962|UniProtKB=M9PEM2 M9PEM2 Dm_2L:23546 PTHR22774:SF11 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN lipid transfer activity#GO:0120013;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 localization#GO:0051179;cellular localization#GO:0051641;lipid localization#GO:0010876;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0286783|UniProtKB=Q7JWF1 Q7JWF1 Etf-QO PTHR10617:SF107 ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL electron transfer activity#GO:0009055;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 electron transport chain#GO:0022900;metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 oxidoreductase#PC00176 DROME|FlyBase=FBgn0033995|UniProtKB=Q3ZAN1 Q3ZAN1 GPHR PTHR15948:SF8 G-PROTEIN COUPLED RECEPTOR 89-RELATED GOLGI PH REGULATOR A-RELATED voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0266354|UniProtKB=Q8IR04 Q8IR04 CG9059 PTHR11731:SF135 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED VENOM DIPEPTIDYL PEPTIDASE 4 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203;protease#PC00190 DROME|FlyBase=FBgn0027053|UniProtKB=Q9XZ58 Q9XZ58 CSN5 PTHR10410:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 5 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224 PDGF signaling pathway#P00047>c-Jun#P01163 DROME|FlyBase=FBgn0024364|UniProtKB=O46307 O46307 EG:8D8.4 PTHR12202:SF0 ESF1 HOMOLOG ESF1 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 DROME|FlyBase=FBgn0030927|UniProtKB=Q9VWU0 Q9VWU0 Dmel\CG15046 PTHR16021:SF13 MANSC DOMAIN CONTAINING PROTEIN 1 EARTHBOUND 1-RELATED DROME|FlyBase=FBgn0038422|UniProtKB=Q9VEW1 Q9VEW1 js PTHR22933:SF44 FI18007P1-RELATED JIANGSHI, ISOFORM A DROME|FlyBase=FBgn0029814|UniProtKB=Q9W468 Q9W468 Dmel\CG15765 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED DROME|FlyBase=FBgn0003041|UniProtKB=Q8IQ97 Q8IQ97 pbl PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cytokinesis#GO:0000910;mitotic cell cycle process#GO:1903047;cytoskeleton-dependent cytokinesis#GO:0061640;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cell cortex#GO:0005938;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0037436|UniProtKB=Q9VI12 Q9VI12 Hr83 PTHR24083:SF155 NUCLEAR HORMONE RECEPTOR HORMONE RECEPTOR 83 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0038348|UniProtKB=Q8IND5 Q8IND5 AOX2 PTHR11908:SF132 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE 1-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0028422|UniProtKB=Q9TVI0 Q9TVI0 GluRIID PTHR18966:SF349 IONOTROPIC GLUTAMATE RECEPTOR FI04462P-RELATED transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536 plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0037174|UniProtKB=Q59E08 Q59E08 Jhbp6 PTHR11008:SF25 PROTEIN TAKEOUT-LIKE PROTEIN IP09473P-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0036108|UniProtKB=Q9VTC6 Q9VTC6 Cpr67Fa1 PTHR10380:SF230 CUTICLE PROTEIN CUTICULAR PROTEIN 47EE-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0034537|UniProtKB=Q7K3D8 Q7K3D8 DMAP1 PTHR12855:SF10 DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;H4 histone acetyltransferase complex#GO:1902562;nuclear chromosome#GO:0000228 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0050185|UniProtKB=Q8MKK1 Q8MKK1 AIMP3 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 enzyme activator activity#GO:0008047;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;positive regulation of apoptotic process#GO:0043065;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135;positive regulation of signaling#GO:0023056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 translation elongation factor#PC00222;translation factor#PC00223 DROME|FlyBase=FBgn0033734|UniProtKB=Q7K4T8 Q7K4T8 FBgn 33734 PTHR12169:SF6 ATPASE N2B AFG1-LIKE ATPASE ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0031772|UniProtKB=Q9VMI2 Q9VMI2 Dmel\CG13994 PTHR20835:SF0 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 enzyme regulator activity#GO:0030234;protein binding#GO:0005515;protein phosphatase regulator activity#GO:0019888;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;phosphatase regulator activity#GO:0019208;protein phosphatase binding#GO:0019903;molecular function regulator activity#GO:0098772 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0031298|UniProtKB=Q9VPW2 Q9VPW2 Atg4a PTHR22624:SF60 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;catalytic activity, acting on a protein#GO:0140096 organelle assembly#GO:0070925;proteolysis#GO:0006508;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;autophagosome organization#GO:1905037;protein processing#GO:0016485;cellular process#GO:0009987;autophagy#GO:0006914;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 DROME|FlyBase=FBgn0032782|UniProtKB=Q9VIW6 Q9VIW6 Rab9 PTHR47981:SF1 RAB FAMILY SMALL MONOMERIC GTPASE hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 lytic vacuole organization#GO:0080171;transport#GO:0006810;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;intracellular transport#GO:0046907;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;organelle assembly#GO:0070925;vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;cytosolic transport#GO:0016482;endocytosis#GO:0006897 lytic vacuole#GO:0000323;late endosome#GO:0005770;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasm#GO:0005737;vacuole#GO:0005773;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982 small GTPase#PC00208 DROME|FlyBase=FBgn0035636|UniProtKB=Q9VRP8 Q9VRP8 Cralbp PTHR10174:SF120 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CELLULAR RETINALDEHYDE BINDING PROTEIN ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0030940|UniProtKB=Q9VWS5 Q9VWS5 Dmel\CG15040 PTHR42264:SF6 EPHRIN_REC_LIKE DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE PROTEIN-RELATED DROME|FlyBase=FBgn0037890|UniProtKB=A0A0B4K6E6 A0A0B4K6E6 BcDNA:RH54117 PTHR12297:SF21 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN-CONTAINING PROTEIN mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0034335|UniProtKB=Q7KK90 Q7KK90 GstE1 PTHR43969:SF4 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED FI01423P-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0083953|UniProtKB=Q0KI97 Q0KI97 Dmel\CG34117 PTHR31716:SF1 PROTEIN FMC1 HOMOLOG PROTEIN FMC1 HOMOLOG mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0259143|UniProtKB=Q9VYM7 Q9VYM7 Pripl4 PTHR20916:SF26 CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993 DROME|FlyBase=FBgn0038223|UniProtKB=A0A4D6K2J4 A0A4D6K2J4 Afti PTHR16156:SF10 AFTIPHILIN A-RELATED AFTIPHILIN A binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 coated membrane#GO:0048475;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin vesicle coat#GO:0030125;trans-Golgi network membrane#GO:0032588;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506 DROME|FlyBase=FBgn0286977|UniProtKB=A0A6H2EDL7 A0A6H2EDL7 Osi10b PTHR21879:SF24 FI03362P-RELATED-RELATED OSIRIS 10B membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037377|UniProtKB=Q9VNI3 Q9VNI3 Hpf1 PTHR13386:SF1 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0036205|UniProtKB=Q9VTN4 Q9VTN4 Dmel\CG14131 PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED ACTIN NUCLEATION-PROMOTING FACTOR WAS-RELATED enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267 cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0036206|UniProtKB=Q9VTN6 Q9VTN6 twy PTHR33689:SF1 FAS-BINDING FACTOR 1 FAS-BINDING FACTOR 1 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0025463|UniProtKB=Q9VYG2 Q9VYG2 Bap60 PTHR13844:SF95 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D BRAHMA-ASSOCIATED PROTEIN OF 60 KDA transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 DROME|FlyBase=FBgn0032153|UniProtKB=Q9VL77 Q9VL77 Dmel\CG4537 PTHR11805:SF2 CYSTEINE-RICH PDZ-BINDING PROTEIN CYSTEINE-RICH PDZ-BINDING PROTEIN protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 dendrite#GO:0030425;dendritic tree#GO:0097447;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0016687|UniProtKB=O77460 O77460 Nurf-38 PTHR10286:SF92 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 pyrophosphatase#PC00196 DROME|FlyBase=FBgn0029687|UniProtKB=Q9W4N8 Q9W4N8 Vap33 PTHR10809:SF6 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN AT11025P-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0036314|UniProtKB=Q9VU15 Q9VU15 Sf3a2 PTHR23205:SF0 SPLICING FACTOR 3A SUBUNIT 2 SPLICING FACTOR 3A SUBUNIT 2 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397 protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0036949|UniProtKB=Q9VW91 Q9VW91 Dmel\CG7290 PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED carbohydrate derivative binding#GO:0097367;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039520|UniProtKB=Q9VB30 Q9VB30 Gr98a PTHR21143:SF104 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 8A-RELATED dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0264810|UniProtKB=Q9VJS7 Q9VJS7 Pburs PTHR41151:SF1 PARTNER OF BURSICON PARTNER OF BURSICON receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028990|UniProtKB=Q9V3N1 Q9V3N1 Spn27A PTHR11461:SF357 SERINE PROTEASE INHIBITOR, SERPIN SERINE PROTEASE INHIBITOR 27A enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Toll pathway-drosophila#P06217>SPN27A#P06341 DROME|FlyBase=FBgn0001259|UniProtKB=Q9VPH0 Q9VPH0 in PTHR21082:SF4 PROTEIN INTURNED PROTEIN INTURNED cilium organization#GO:0044782;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028897|UniProtKB=Q9VJL9 Q9VJL9 MET30 PTHR22842:SF3 WD40 REPEAT PROTEIN WD REPEAT DOMAIN-CONTAINING PROTEIN 83 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0015299|UniProtKB=Q9VLR5 Q9VLR5 Ssb-c31a PTHR13215:SF0 RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0003891|UniProtKB=P25823 P25823 tud PTHR22948:SF84 TUDOR DOMAIN CONTAINING PROTEIN FI02030P-RELATED embryo development#GO:0009790;oogenesis#GO:0048477;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;embryonic pattern specification#GO:0009880;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;anterior/posterior axis specification#GO:0009948;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anterior/posterior pattern specification#GO:0009952;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;regionalization#GO:0003002;developmental maturation#GO:0021700;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;cell maturation#GO:0048469;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;sexual reproduction#GO:0019953;piRNA processing#GO:0034587 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0002561|UniProtKB=P09774 P09774 l(1)sc PTHR13935:SF153 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE FAMILY BHLH TRANSCRIPTION FACTOR 1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;sensory organ development#GO:0007423;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0003676|UniProtKB=P12613 P12613 CCT1 PTHR11353:SF84 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein folding chaperone complex#GO:0101031;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperonin#PC00073 DROME|FlyBase=FBgn0043903|UniProtKB=Q9VWE0 Q9VWE0 dome PTHR46957:SF13 CYTOKINE RECEPTOR CYTOKINE RECEPTOR transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0033901|UniProtKB=Q9V6X7 Q9V6X7 O-fut1 PTHR21420:SF10 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0083983|UniProtKB=Q0E959 Q0E959 mRpL34 PTHR14503:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233 ribosomal protein#PC00202 DROME|FlyBase=FBgn0085453|UniProtKB=Q8MLS1 Q8MLS1 Mthfs PTHR23407:SF1 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142 DROME|FlyBase=FBgn0041181|UniProtKB=Q9VLY7 Q9VLY7 Tep3 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease inhibitor#PC00191 DROME|FlyBase=FBgn0024941|UniProtKB=Q9VXA3 Q9VXA3 RSG7 PTHR45746:SF6 LP21163P LP21163P molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 DROME|FlyBase=FBgn0034314|UniProtKB=Q7K2X1 Q7K2X1 nopo PTHR46569:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRAIP E3 UBIQUITIN-PROTEIN LIGASE TRAIP aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein modification by small protein conjugation or removal#GO:0070647;DNA-templated DNA replication#GO:0006261;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;DNA replication#GO:0006260;primary metabolic process#GO:0044238;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;replication fork processing#GO:0031297 chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0004870|UniProtKB=Q9W0K7 Q9W0K7 bab1 PTHR23110:SF116 BTB DOMAIN TRANSCRIPTION FACTOR PROTEIN BRIC-A-BRAC 1-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0051673|UniProtKB=Q9VII9 Q9VII9 CCG31673 PTHR10996:SF119 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 DROME|FlyBase=FBgn0050172|UniProtKB=Q8MLP9 Q8MLP9 BcDNA:RH70879 PTHR11257:SF8 CHEMOSENSORY PROTEIN-RELATED GEO08457P1 DROME|FlyBase=FBgn0261697|UniProtKB=Q9VMH0 Q9VMH0 tctn PTHR14611:SF7 TECTONIC FAMILY MEMBER TECTONIC cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 DROME|FlyBase=FBgn0290417|UniProtKB=Q9VBI1 Q9VBI1 Sld5 PTHR21206:SF0 SLD5 PROTEIN DNA REPLICATION COMPLEX GINS PROTEIN SLD5 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0266452|UniProtKB=Q9VUL1 Q9VUL1 Ctps PTHR11550:SF47 CTP SYNTHASE CTP SYNTHASE 1-RELATED identical protein binding#GO:0042802;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;ligase activity#GO:0016874;binding#GO:0005488;catalytic activity#GO:0003824 nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 DROME|FlyBase=FBgn0035436|UniProtKB=Q9VZR0 Q9VZR0 Nmrk PTHR10285:SF158 URIDINE KINASE SD05789P2 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;nucleotide kinase#PC00172 DROME|FlyBase=FBgn0035607|UniProtKB=Q9VRL7 Q9VRL7 Dmel\CG4835 PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED carbohydrate derivative binding#GO:0097367;binding#GO:0005488 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312 DROME|FlyBase=FBgn0031733|UniProtKB=Q9VMN0 Q9VMN0 Dmel\CG14006 PTHR13598:SF1 AT07567P-RELATED AT07567P-RELATED intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0266582|UniProtKB=Q9VZU4 Q9VZU4 ND-30 PTHR10884:SF17 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0033953|UniProtKB=Q8T465 Q8T465 Dmel\CG12861 PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0010397|UniProtKB=Q03427 Q03427 LamC PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;intracellular protein localization#GO:0008104;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;nucleus organization#GO:0006997;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;membrane organization#GO:0061024;localization within membrane#GO:0051668;organelle localization#GO:0051640;localization#GO:0051179;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;regulation of macromolecule metabolic process#GO:0060255;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular localization#GO:0051641;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;establishment of organelle localization#GO:0051656 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229 FAS signaling pathway#P00020>Nuclear Lamin#P00616 DROME|FlyBase=FBgn0259834|UniProtKB=Q9V3F9 Q9V3F9 out PTHR11360:SF8 MONOCARBOXYLATE TRANSPORTER BCDNA.LD28120-RELATED transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0267861|UniProtKB=Q7PL26 Q7PL26 Maf1 PTHR22504:SF0 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0036516|UniProtKB=Q9VUR4 Q9VUR4 Dmel\CG7656 PTHR24067:SF157 UBIQUITIN-CONJUGATING ENZYME E2 FI11905P aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0283525|UniProtKB=Q9VPX3 Q9VPX3 l(2)10685 PTHR22808:SF3 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING NOL1_NOP2_SUN DOMAIN FAMILY MEMBER 4 catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0034756|UniProtKB=Q9W223 Q9W223 Cyp6d2 PTHR24292:SF93 CYTOCHROME P450 CYTOCHROME P450 310A1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0031961|UniProtKB=Q9VLV6 Q9VLV6 CG17973 PTHR24410:SF51 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN-RELATED defense/immunity protein#PC00090 DROME|FlyBase=FBgn0033187|UniProtKB=A1Z705 A1Z705 PIG-G PTHR23072:SF0 PHOSPHATIDYLINOSITOL GLYCAN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2, CATALYTIC SUBUNIT transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 DROME|FlyBase=FBgn0038219|UniProtKB=Q9VFL2 Q9VFL2 Dmel\CG14839 PTHR37161:SF2 HDC10475 AT11648P-RELATED DROME|FlyBase=FBgn0085220|UniProtKB=A8DYH2 A8DYH2 Ufm1 PTHR15825:SF0 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;autophagy#GO:0006914;reticulophagy#GO:0061709;response to stress#GO:0006950;macroautophagy#GO:0016236;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0003139|UniProtKB=Q27884 Q27884 PpV PTHR45619:SF10 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 DROME|FlyBase=FBgn0038396|UniProtKB=Q9VEZ4 Q9VEZ4 Dmel\CG5013 PTHR14614:SF167 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTONE-ARGININE METHYLTRANSFERASE METTL23 histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0262518|UniProtKB=O18338 O18338 Rab8 PTHR47980:SF101 LD44762P IP08727P-RELATED endocytic recycling#GO:0032456;export from cell#GO:0140352;localization within membrane#GO:0051668;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;exocytosis#GO:0006887;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876 clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;trans-Golgi network transport vesicle#GO:0030140;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 DROME|FlyBase=FBgn0266418|UniProtKB=X4YX01 X4YX01 wake PTHR21437:SF1 WIDE AWAKE WIDE AWAKE microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;mitotic cell cycle process#GO:1903047;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of establishment or maintenance of cell polarity#GO:0032878;organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;spindle localization#GO:0051653;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;establishment of organelle localization#GO:0051656;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0044048|UniProtKB=Q7KUD5 Q7KUD5 Ilp5 PTHR13647:SF4 INSULIN-LIKE PEPTIDE 2-RELATED INSULIN-LIKE PEPTIDE 1-RELATED DROME|FlyBase=FBgn0032211|UniProtKB=Q9VL03 Q9VL03 Dmel\CG13138 PTHR47771:SF12 LD27203P-RELATED HL02234P-RELATED DROME|FlyBase=FBgn0039779|UniProtKB=Q9I7H5 Q9I7H5 PH4alphaSG2 PTHR10869:SF256 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROCOLLAGEN-PROLINE 4-DIOXYGENASE protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030614|UniProtKB=Q9VXY1 Q9VXY1 Dmel\CG9072 PTHR21500:SF0 TUBULIN-SPECIFIC CHAPERONE A TUBULIN-SPECIFIC CHAPERONE A protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chaperonin#PC00073 DROME|FlyBase=FBgn0038407|UniProtKB=Q961R9 Q961R9 CT19169 PTHR24064:SF702 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0005198|UniProtKB=Q9VW83 Q9VW83 gig PTHR10063:SF0 TUBERIN TUBERIN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of cell cycle#GO:0051726;positive regulation of macroautophagy#GO:0016239;signaling#GO:0023052;response to stimulus#GO:0050896;negative regulation of TORC1 signaling#GO:1904262;regulation of macroautophagy#GO:0016241;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of autophagy#GO:0010508;negative regulation of signal transduction#GO:0009968;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 G-protein modulator#PC00022;GTPase-activating protein#PC00257 p53 pathway by glucose deprivation#P04397>TSC2#P04644;p53 pathway by glucose deprivation#P04397>TSC2#G04706;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC2#P04494 DROME|FlyBase=FBgn0259481|UniProtKB=Q8IQG1 Q8IQG1 Mob2 PTHR22599:SF21 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2 protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase activator#PC00138 DROME|FlyBase=FBgn0017572|UniProtKB=P91891 P91891 Mo25 PTHR10182:SF3 CALCIUM-BINDING PROTEIN 39-RELATED PROTEIN MO25 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295 DROME|FlyBase=FBgn0032058|UniProtKB=Q9VLJ1 Q9VLJ1 Dmel\CG9289 PTHR43142:SF12 CARBOXYLIC ESTER HYDROLASE CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN-RELATED hydrolase#PC00121 DROME|FlyBase=FBgn0259150|UniProtKB=B7Z0W9 B7Z0W9 OtopLc PTHR21522:SF32 PROTON CHANNEL OTOP PROTON CHANNEL OTOPLC transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0029839|UniProtKB=Q9W439 Q9W439 BcDNA:RH58440 PTHR12475:SF4 FAMILY NOT NAMED PROTEIN THEM6 DROME|FlyBase=FBgn0005666|UniProtKB=D1YSG0 D1YSG0 bt PTHR13817:SF151 TITIN BENT, ISOFORM F-RELATED structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actomyosin structure organization#GO:0031032;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214 contractile muscle fiber#GO:0043292;A band#GO:0031672;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;M band#GO:0031430;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017 structural protein#PC00211 DROME|FlyBase=FBgn0036446|UniProtKB=Q9VUH4 Q9VUH4 Mgat4a PTHR12062:SF9 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A, ISOFORM A-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220 DROME|FlyBase=FBgn0000045|UniProtKB=P02574 P02574 Act79B PTHR11937:SF387 ACTIN ACTIN, INDIRECT FLIGHT MUSCLE-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 DROME|FlyBase=FBgn0035790|UniProtKB=Q9VS78 Q9VS78 Cyp316a1 PTHR24291:SF187 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4AE1-RELATED metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0033794|UniProtKB=Q7JYM7 Q7JYM7 Dmel\CG13326 PTHR46618:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 3 ARMADILLO REPEAT-CONTAINING PROTEIN 3 DROME|FlyBase=FBgn0052982|UniProtKB=E1JHC2 E1JHC2 CG18566 PTHR12092:SF16 PLECKSTRIN PH DOMAIN-CONTAINING PROTEIN cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0263236|UniProtKB=Q0KI00 Q0KI00 SP1029 PTHR11533:SF253 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0034315|UniProtKB=Q7K486 Q7K486 CG5721 PTHR22895:SF9 ARMADILLO REPEAT-CONTAINING PROTEIN 6 ARMADILLO REPEAT-CONTAINING PROTEIN 6 cell development#GO:0048468;hemopoiesis#GO:0030097;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DROME|FlyBase=FBgn0027518|UniProtKB=Q9XZ25 Q9XZ25 Wdr24 PTHR46200:SF1 GATOR COMPLEX PROTEIN WDR24 GATOR2 COMPLEX PROTEIN WDR24 positive regulation of macroautophagy#GO:0016239;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;cellular response to amino acid starvation#GO:0034198;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of macroautophagy#GO:0016241;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;positive regulation of TOR signaling#GO:0032008;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;cellular response to starvation#GO:0009267 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;Seh1-associated complex#GO:0035859;vacuolar membrane#GO:0005774;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DROME|FlyBase=FBgn0039408|UniProtKB=Q9VBH6 Q9VBH6 Cfap97D PTHR33768:SF3 MIP11318P MIP11318P DROME|FlyBase=FBgn0264908|UniProtKB=M9PI70 M9PI70 pHCl-1 PTHR18945:SF819 NEUROTRANSMITTER GATED ION CHANNEL PH-SENSITIVE CHLORIDE CHANNEL 1, ISOFORM N excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267 transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0031904|UniProtKB=Q9VM22 Q9VM22 Dmel\CG5149 PTHR23354:SF133 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED MTOR-ASSOCIATED PROTEIN MEAK7 response to oxidative stress#GO:0006979;response to stimulus#GO:0050896;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0024993|UniProtKB=Q9W4W7 Q9W4W7 Lint-O PTHR12247:SF138 POLYCOMB GROUP PROTEIN L(3)MBT INTERACTOR IN OVARIAN SOMATIC CELLS, ISOFORM A-RELATED binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transferase complex#GO:1990234;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0259174|UniProtKB=Q9VVI3 Q9VVI3 Nedd4 PTHR11254:SF447 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD-4 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;transporter regulator activity#GO:0141108;ubiquitin protein ligase activity#GO:0061630;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772 regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of cell projection organization#GO:0031344;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of developmental process#GO:0050793;primary metabolic process#GO:0044238;regulation of dendrite morphogenesis#GO:0048814;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0037402|UniProtKB=Q9VNL3 Q9VNL3 Vha14-2 PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0034915|UniProtKB=P56538 P56538 eIF6 PTHR10784:SF0 TRANSLATION INITIATION FACTOR 6 EUKARYOTIC TRANSLATION INITIATION FACTOR 6 protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;rRNA metabolic process#GO:0016072;intracellular transport#GO:0046907;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nuclear transport#GO:0051169;rRNA processing#GO:0006364;nuclear export#GO:0051168;localization#GO:0051179;protein-RNA complex assembly#GO:0022618;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;organelle assembly#GO:0070925;organelle localization#GO:0051640 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translation initiation factor#PC00224 DROME|FlyBase=FBgn0051706|UniProtKB=Q8T0P4 Q8T0P4 BcDNA:GH07269 PTHR38572:SF1 BCDNA.GH07269-RELATED BCDNA.GH07269-RELATED DROME|FlyBase=FBgn0034383|UniProtKB=A1ZBD2 A1ZBD2 Dmel\CG17821 PTHR11157:SF116 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0015766|UniProtKB=Q8IQ63 Q8IQ63 Msr-110 PTHR31802:SF54 32 KDA HEAT SHOCK PROTEIN-RELATED MARTIK, ISOFORM A-RELATED intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0051363|UniProtKB=Q9I7K0 Q9I7K0 Jupiter PTHR34930:SF2 GEO05313P1 MICROTUBULE-ASSOCIATED PROTEIN JUPITER microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0035697|UniProtKB=Q9VRW5 Q9VRW5 Dmel\CG10163 PTHR11610:SF192 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0013674|UniProtKB=P00399 P00399 mt:CoI PTHR10422:SF18 CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 1 monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidase#PC00175;oxidoreductase#PC00176 ATP synthesis#P02721>Cytochrome oxidase aa3#P02793 DROME|FlyBase=FBgn0051619|UniProtKB=Q0E8N3 Q0E8N3 nolo PTHR13723:SF315 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE NO LONG NERVE CORD, ISOFORM C endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 DROME|FlyBase=FBgn0250823|UniProtKB=A0A0B4KHL4 A0A0B4KHL4 gish PTHR11909:SF520 CASEIN KINASE-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944 non-receptor serine/threonine protein kinase#PC00167 Parkinson disease#P00049>Casein kinase I#P01242;Wnt signaling pathway#P00057>Casein Kinase 1#P01460 DROME|FlyBase=FBgn0036880|UniProtKB=Q4V6L8 Q4V6L8 Cpr76Bc PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0261284|UniProtKB=Q9W3T7 Q9W3T7 bou PTHR33562:SF18 ATILLA, ISOFORM B-RELATED-RELATED RE19849P-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0034700|UniProtKB=Q9W286 Q9W286 Dmel\CG11269 PTHR31733:SF1 RIBONUCLEASE KAPPA RIBONUCLEASE KAPPA monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 proton-transporting two-sector ATPase complex#GO:0016469;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 endoribonuclease#PC00094 DROME|FlyBase=FBgn0263354|UniProtKB=M9MRJ1 M9MRJ1 CR31846 PTHR13129:SF4 VPRBP PROTEIN-RELATED PROTEIN MAHJONG Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0036272|UniProtKB=X2JGL7 X2JGL7 Sms PTHR46315:SF1 SPERMINE SYNTHASE SPERMINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;polyamine biosynthetic process#GO:0006596 DROME|FlyBase=FBgn0022786|UniProtKB=O17468 O17468 Hira PTHR13831:SF0 MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS PROTEIN HIRA binding#GO:0005488;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0267390|UniProtKB=Q9VUQ9 Q9VUQ9 dop PTHR24356:SF414 SERINE/THREONINE-PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;signaling#GO:0023052 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0052570|UniProtKB=Q8IR10 Q8IR10 TwdlY PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 DROME|FlyBase=FBgn0250836|UniProtKB=Q9VS22 Q9VS22 Acbp3 PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0035587|UniProtKB=Q9VRJ3 Q9VRJ3 Gdap1 PTHR44188:SF1 GDAP1, ISOFORM A GDAP1, ISOFORM A cellular process#GO:0009987;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266;organelle fusion#GO:0048284;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285 membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0050067|UniProtKB=A1Z9Q2 A1Z9Q2 Obp50a PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0037050|UniProtKB=Q9VP78 Q9VP78 ICA69 PTHR10164:SF4 ISLET CELL AUTOANTIGEN 1 GH23156P molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 cellular component organization or biogenesis#GO:0071840;regulation of secretion#GO:0051046;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;membrane organization#GO:0061024;biological regulation#GO:0065007 membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 DROME|FlyBase=FBgn0005660|UniProtKB=P29776 P29776 Ets21C PTHR11849:SF305 ETS DNA-BINDING PROTEIN D-ETS-6 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 DROME|FlyBase=FBgn0034572|UniProtKB=Q9W2N6 Q9W2N6 cg9346 PTHR23140:SF0 RNA PROCESSING PROTEIN LD23810P U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147 DROME|FlyBase=FBgn0051681|UniProtKB=Q8IPY7 Q8IPY7 Dmel\CG31681 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0019662|UniProtKB=Q9VS54 Q9VS54 qm PTHR12001:SF44 GERANYLGERANYL PYROPHOSPHATE SYNTHASE GERANYLGERANYL PYROPHOSPHATE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;isoprenoid metabolic process#GO:0006720;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 DROME|FlyBase=FBgn0028562|UniProtKB=Q9U622 Q9U622 sut2 PTHR23503:SF127 SOLUTE CARRIER FAMILY 2 FI08437P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 transport#GO:0006810;cellular process#GO:0009987;carbohydrate transport#GO:0008643;carbohydrate transmembrane transport#GO:0034219;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0037090|UniProtKB=Q9VP25 Q9VP25 Est-Q PTHR43142:SF12 CARBOXYLIC ESTER HYDROLASE CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN-RELATED hydrolase#PC00121 DROME|FlyBase=FBgn0260990|UniProtKB=Q9VAH7 Q9VAH7 yata PTHR12984:SF3 SCY1-RELATED S/T PROTEIN KINASE-LIKE N-TERMINAL KINASE-LIKE PROTEIN non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0035850|UniProtKB=M9PER1 M9PER1 Atg18a PTHR11227:SF17 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED AUTOPHAGY-RELATED 18A, ISOFORM E phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674 organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;localization#GO:0051179;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;intracellular protein localization#GO:0008104;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component assembly#GO:0022607 membrane#GO:0016020;phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031710|UniProtKB=Q9VMQ8 Q9VMQ8 Vps52 PTHR14190:SF16 SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG binding#GO:0005488;SNARE binding#GO:0000149;syntaxin binding#GO:0019905;protein binding#GO:0005515 cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;lysosomal transport#GO:0007041;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0015772|UniProtKB=Q9VJ30 Q9VJ30 Nak PTHR22967:SF107 SERINE/THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of Notch signaling pathway#GO:0045747;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of response to stimulus#GO:0048583;regulation of endocytosis#GO:0030100 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0027654|UniProtKB=Q9TVP3 Q9TVP3 jdp PTHR44500:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0265048|UniProtKB=Q9VF24 Q9VF24 cv-d PTHR23345:SF33 VITELLOGENIN-RELATED CROSSVEINLESS D lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 storage protein#PC00210 DROME|FlyBase=FBgn0010391|UniProtKB=Q9U5L1 Q9U5L1 SrpRalpha PTHR43134:SF1 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;protein-containing complex binding#GO:0044877;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 establishment of protein localization#GO:0045184;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to ER#GO:0045047;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein targeting#GO:0006605 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;G-protein#PC00020 DROME|FlyBase=FBgn0050145|UniProtKB=Q9V938 Q9V938 Obp57e PTHR11857:SF48 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 57C-RELATED sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0031814|UniProtKB=Q9VMD6 Q9VMD6 retm PTHR23324:SF66 SEC14 RELATED PROTEIN PROTEIN REAL-TIME intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0022764|UniProtKB=A0A0B4K765 A0A0B4K765 Sin3A PTHR12346:SF71 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771 DROME|FlyBase=FBgn0040271|UniProtKB=Q9VEX0 Q9VEX0 Sulf1 PTHR43108:SF16 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-1 HOMOLOG catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;carbohydrate derivative metabolic process#GO:1901135;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of cytokine production#GO:0001819;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycoprotein metabolic process#GO:0009100;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121 DROME|FlyBase=FBgn0038659|UniProtKB=Q8T390 Q8T390 EndoA PTHR14167:SF124 SH3 DOMAIN-CONTAINING ENDOPHILIN-A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cytoplasm#GO:0005737;cytosol#GO:0005829;presynapse#GO:0098793;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031491|UniProtKB=Q9VQK4 Q9VQK4 alpha4GT1 PTHR12042:SF31 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE 1-RELATED hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0037792|UniProtKB=Q9VH20 Q9VH20 TAF1B PTHR31576:SF6 TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 gene expression#GO:0010467;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription by RNA polymerase I#GO:0006360;rRNA transcription#GO:0009303;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 General transcription by RNA polymerase I#P00022>TAF-IB#P00650 DROME|FlyBase=FBgn0265193|UniProtKB=Q2PE13 Q2PE13 Atf-2 PTHR19304:SF47 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN ACTIVATING TRANSCRIPTION FACTOR-2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0031030|UniProtKB=Q0KHQ5 Q0KHQ5 Tao PTHR47167:SF4 SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN SERINE_THREONINE-PROTEIN KINASE TAO phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0029942|UniProtKB=Q9W3R8 Q9W3R8 Dmel\CG2059 PTHR46118:SF4 PROTEIN ABHD11 SN-1-SPECIFIC DIACYLGLYCEROL LIPASE ABHD11 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0003392|UniProtKB=P27619 P27619 shi PTHR11566:SF212 DYNAMIN DYNAMIN binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;microtubule binding#GO:0008017;protein binding#GO:0005515;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0031832|UniProtKB=Q8MS69 Q8MS69 Trmt6 PTHR12945:SF0 TRANSLATION INITIATION FACTOR EIF3-RELATED TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 translation initiation factor#PC00224 DROME|FlyBase=FBgn0263110|UniProtKB=M9MRV7 M9MRV7 CG1295 PTHR13743:SF165 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 1 ISOFORM X1 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0013433|UniProtKB=X2J8L2 X2J8L2 beat-Ia PTHR21261:SF8 BEAT PROTEIN BEATEN PATH IA, ISOFORM B-RELATED generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0038063|UniProtKB=Q4LBB9 Q4LBB9 Octbeta2R PTHR24248:SF187 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OCTOPAMINE RECEPTOR BETA-2R G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0040507|UniProtKB=Q9W038 Q9W038 ACXD PTHR45627:SF12 ADENYLATE CYCLASE TYPE 1 ADENYLYL CYCLASE X E-RELATED catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0033677|UniProtKB=Q7K0Q0 Q7K0Q0 Dmel\CG8321 PTHR28640:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 DROME|FlyBase=FBgn0051858|UniProtKB=Q8IP85 Q8IP85 t-cup PTHR10281:SF76 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED CALCUTTA CUP-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0038739|UniProtKB=Q9VDT4 Q9VDT4 BcDNA:AT09463 PTHR43461:SF1 TRANSMEMBRANE PROTEIN 256 TRANSMEMBRANE PROTEIN 256 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0020644|UniProtKB=C0HL62 C0HL62 Lcp65Ab1 PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0036194|UniProtKB=Q9VTM2 Q9VTM2 Dph1 PTHR10762:SF1 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1 protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 DROME|FlyBase=FBgn0011660|UniProtKB=A1ZA03 A1ZA03 Pms2 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2 ISOFORM X1 DNA endonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536 response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0259194|UniProtKB=Q9VCM4 Q9VCM4 Ir94e PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036520|UniProtKB=Q9VUR8 Q9VUR8 Dmel\CG13449 PTHR36696:SF1 AGAP012002-PA EF-HAND DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0005616|UniProtKB=P50534 P50534 msl-2 PTHR16048:SF3 MSL2-RELATED E3 UBIQUITIN-PROTEIN LIGASE MSL2 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785 DROME|FlyBase=FBgn0033988|UniProtKB=Q9V785 Q9V785 pcs PTHR19423:SF1 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0052075|UniProtKB=Q8SZY9 Q8SZY9 CG6316 PTHR15002:SF0 RIBOSOMAL BIOGENESIS PROTEIN LAS1L RIBOSOMAL BIOGENESIS PROTEIN LAS1L endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0028494|UniProtKB=Q0E938 Q0E938 anon-WO0153538.32 PTHR15904:SF17 FAM13 RHO-GAP DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0038380|UniProtKB=Q9VF16 Q9VF16 Gyc89A PTHR44755:SF8 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED RECEPTOR LIGAND BINDING REGION DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;hormone binding#GO:0042562;binding#GO:0005488 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0031643|UniProtKB=Q9VR42 Q9VR42 Dmel\CG3008 PTHR45723:SF1 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO3 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031020|UniProtKB=Q9VWI2 Q9VWI2 Naa15-16 PTHR22767:SF18 N-TERMINAL ACETYLTRANSFERASE-RELATED N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;transferase complex#GO:1990234;catalytic complex#GO:1902494 acetyltransferase#PC00038 DROME|FlyBase=FBgn0026430|UniProtKB=Q9XYP7 Q9XYP7 Grip84 PTHR19302:SF13 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 2 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;sexual reproduction#GO:0019953 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0036952|UniProtKB=Q9VW94 Q9VW94 Dmel\CG6933 PTHR23301:SF115 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0040395|UniProtKB=Q9W525 Q9W525 Unc-76 PTHR12394:SF12 ZYGIN LD08195P neuron projection#GO:0043005;axon#GO:0030424;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038337|UniProtKB=Q9VF65 Q9VF65 Dmel\CG6125 PTHR11814:SF195 SULFATE TRANSPORTER GH25012P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0040658|UniProtKB=Q2PE16 Q2PE16 Dmel\CG13516 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039038|UniProtKB=Q9VCS4 Q9VCS4 Dmel\CG6688 PTHR14191:SF3 PDZ DOMAIN CONTAINING PROTEIN GH04176P-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036858|UniProtKB=Q9VVX9 Q9VVX9 SPH199 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0266671|UniProtKB=Q9V8K2 Q9V8K2 Sec6 PTHR21292:SF1 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3 SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;exocytosis#GO:0006887;secretion by cell#GO:0032940 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;exocyst#GO:0000145;cytoplasm#GO:0005737;cell cortex#GO:0005938;cell periphery#GO:0071944;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0033264|UniProtKB=Q7K0D8 Q7K0D8 Nup50 PTHR23138:SF141 RAN BINDING PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP50 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030247|UniProtKB=Q9VZ54 Q9VZ54 lincRNA.977 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410 DROME|FlyBase=FBgn0001297|UniProtKB=P21525 P21525 kay PTHR23351:SF24 FOS TRANSCRIPTION FACTOR-RELATED ACTIVATING TRANSCRIPTION FACTOR 3-RELATED basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0002938|UniProtKB=P10676 P10676 ninaC PTHR46256:SF2 AGAP011099-PA NEITHER INACTIVATION NOR AFTERPOTENTIAL PROTEIN C kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;macromolecular conformation isomerase activity#GO:0120543;transferase activity#GO:0016740;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological quality#GO:0065008;cellular component organization or biogenesis#GO:0071840;regulation of actin filament length#GO:0030832;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 DROME|FlyBase=FBgn0033074|UniProtKB=A1Z6L1 A1Z6L1 tomboy40 PTHR10802:SF2 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG 1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transmembrane protein transporter activity#GO:0008320 protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0016120|UniProtKB=Q24251 Q24251 ATPsynD PTHR12700:SF12 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT D, MITOCHONDRIAL channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252 ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145 mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0010452|UniProtKB=M9PFH7 M9PFH7 trn PTHR24373:SF406 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TARTAN, ISOFORM B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0050418|UniProtKB=Q9W192 Q9W192 nord PTHR14619:SF3 NEURON-DERIVED NEUROTROPHIC FACTOR PROTEIN NDNF DROME|FlyBase=FBgn0026148|UniProtKB=Q9VKM0 Q9VKM0 Dmel\CG12253 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0015222|UniProtKB=Q7KRU8 Q7KRU8 Fer1HCH PTHR11431:SF43 FERRITIN FERRITIN HEAVY CHAIN cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 storage protein#PC00210 DROME|FlyBase=FBgn0264979|UniProtKB=Q9VQ96 Q9VQ96 CG31686 PTHR11610:SF192 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0259785|UniProtKB=Q9VP57 Q9VP57 pzg PTHR24403:SF110 ZINC FINGER PROTEIN LD15904P binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0011837|UniProtKB=P47980 P47980 Tis11 PTHR12547:SF190 CCCH ZINC FINGER/TIS11-RELATED PROTEIN TIS11 molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0043577|UniProtKB=Q9VV96 Q9VV96 PGRP-SB2 PTHR11022:SF75 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN SB1-RELATED N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0034030|UniProtKB=A1ZA23 A1ZA23 Dmel\CG8192 PTHR22933:SF48 FI18007P1-RELATED FI18007P1 DROME|FlyBase=FBgn0041191|UniProtKB=Q9VND8 Q9VND8 Rheb PTHR24070:SF226 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB HOMOLOG enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;kinase activator activity#GO:0019209;GTPase activity#GO:0003924;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein kinase activator activity#GO:0030295 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of TOR signaling#GO:0032008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;p53 pathway by glucose deprivation#P04397>Rheb#P04642;TGF-beta signaling pathway#P00052>Ras-GDP#P01291 DROME|FlyBase=FBgn0011768|UniProtKB=P46415 P46415 Fdh PTHR43880:SF12 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE CLASS-3 oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;cation binding#GO:0043169;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to chemical#GO:0042221;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;response to toxic substance#GO:0009636;catabolic process#GO:0009056;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 DROME|FlyBase=FBgn0262734|UniProtKB=X2JC79 X2JC79 eIF4H1 PTHR23236:SF120 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4H nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 DROME|FlyBase=FBgn0052091|UniProtKB=Q9VTL3 Q9VTL3 CG7346 PTHR48041:SF105 ABC TRANSPORTER G FAMILY MEMBER 28 FI02074P primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0037615|UniProtKB=Q8INQ3 Q8INQ3 Dmel\CG11760 PTHR13531:SF0 GEO07735P1-RELATED-RELATED GEO07735P1-RELATED plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 cilium#GO:0005929;ciliary transition zone#GO:0035869;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0052645|UniProtKB=Q9VYG5 Q9VYG5 CG4331 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 DROME|FlyBase=FBgn0040207|UniProtKB=Q0KHS0 Q0KHS0 kat80 PTHR19845:SF0 KATANIN P80 SUBUNIT KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;cellular component disassembly#GO:0022411;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0036376|UniProtKB=Q9VU88 Q9VU88 Liprin-beta PTHR12587:SF14 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN AT31531P structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;neuromuscular junction development#GO:0007528 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynaptic active zone#GO:0048786;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035143|UniProtKB=Q9W0Q0 Q9W0Q0 Ppm1 PTHR13832:SF565 PROTEIN PHOSPHATASE 2C PROTEIN-SERINE_THREONINE PHOSPHATASE protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 protein phosphatase#PC00195 DROME|FlyBase=FBgn0030620|UniProtKB=Q8T4F2 Q8T4F2 Dmel\CG5662 PTHR12289:SF38 METAXIN RELATED METAXIN-2 establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0261276|UniProtKB=A1Z9N0 A1Z9N0 Opa1 PTHR11566:SF67 DYNAMIN DYNAMIN-LIKE GTPASE OPA1, MITOCHONDRIAL ribonucleoside triphosphate phosphatase activity#GO:0017111;tubulin binding#GO:0015631;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;microtubule binding#GO:0008017;GTPase activity#GO:0003924 organelle fusion#GO:0048284;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular process#GO:0009987 supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233;organelle membrane#GO:0031090;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;mitochondrial intermembrane space#GO:0005758;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0086611|UniProtKB=Q9I7Q6 Q9I7Q6 Lcp65Ag3 PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0035888|UniProtKB=M9PEJ0 M9PEJ0 Dmel\CG7120 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0010323|UniProtKB=P54366 P54366 Gsc PTHR24329:SF516 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN GOOSECOID transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0032860|UniProtKB=Q9VIM4 Q9VIM4 Dmel\CG15130 PTHR28635:SF2 TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN TRANSMEMBRANE INNER EAR DROME|FlyBase=FBgn0032741|UniProtKB=Q9VJ16 Q9VJ16 Sidpn PTHR10985:SF162 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED GH26014P sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0036518|UniProtKB=B7Z058 B7Z058 RhoGAP71E PTHR23179:SF27 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO GTPASE ACTIVATING PROTEIN AT 71E, ISOFORM D molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0085450|UniProtKB=Q00G30 Q00G30 Snoo PTHR10005:SF25 SKI ONCOGENE-RELATED SNO ONCOGENE, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0037135|UniProtKB=Q9VNX8 Q9VNX8 eIF2A PTHR13227:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2A EUKARYOTIC TRANSLATION INITIATION FACTOR 2A translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2A#P06762 DROME|FlyBase=FBgn0023083|UniProtKB=A0A126GUV7 A0A126GUV7 fray PTHR48012:SF16 STERILE20-LIKE KINASE, ISOFORM B-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 response to osmotic stress#GO:0006970;cellular response to chemical stress#GO:0062197;cellular response to abiotic stimulus#GO:0071214;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to osmotic stress#GO:0071470;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;hyperosmotic response#GO:0006972;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0032078|UniProtKB=Q7K237 Q7K237 C1GalTA PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 transferase#PC00220 DROME|FlyBase=FBgn0051201|UniProtKB=Q0KI42 Q0KI42 GluRIIE PTHR18966:SF349 IONOTROPIC GLUTAMATE RECEPTOR FI04462P-RELATED ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646 plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0086442|UniProtKB=Q9VJ14 Q9VJ14 mib2 PTHR24202:SF4 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB2-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0041150|UniProtKB=Q9VR47 Q9VR47 hoe1 PTHR43568:SF1 P PROTEIN CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0260795|UniProtKB=Q9VTG0 Q9VTG0 NaPi-III PTHR11101:SF97 PHOSPHATE TRANSPORTER PHOSPHATE TRANSPORTER phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081 phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0028789|UniProtKB=Q9U8L5 Q9U8L5 Doc1 PTHR11267:SF204 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR 3B transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cell fate specification#GO:0001708;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 DROME|FlyBase=FBgn0051851|UniProtKB=Q8IP78 Q8IP78 Naa20B PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096 regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 DROME|FlyBase=FBgn0033458|UniProtKB=Q7JZC5 Q7JZC5 Lime PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0028484|UniProtKB=Q9VZI2 Q9VZI2 Ack PTHR24418:SF384 TYROSINE-PROTEIN KINASE ACTIVATED CDC42 KINASE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 DROME|FlyBase=FBgn0262002|UniProtKB=Q7KTH6 Q7KTH6 CG13394 PTHR41967:SF6 FI19406P1-RELATED FI19406P1-RELATED DROME|FlyBase=FBgn0034627|UniProtKB=Q9W2H0 Q9W2H0 eEFSec PTHR43721:SF11 ELONGATION FACTOR TU-RELATED SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 metabolic process#GO:0008152;translational elongation#GO:0006414;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;translation#GO:0006412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794 translation elongation factor#PC00222 DROME|FlyBase=FBgn0001195|UniProtKB=P02255 P02255 His1 PTHR11467:SF36 HISTONE H1 H1.010 LINKER HISTONE, CLUSTER MEMBER-RELATED chromatin DNA binding#GO:0031490;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;regulation of DNA recombination#GO:0000018;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0015381|UniProtKB=Q9VML1 Q9VML1 dsf PTHR24083:SF154 NUCLEAR HORMONE RECEPTOR PROTEIN DISSATISFACTION sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0061476|UniProtKB=Q9VA00 Q9VA00 Zwilch PTHR15995:SF1 PROTEIN ZWILCH HOMOLOG PROTEIN ZWILCH HOMOLOG macromolecule localization#GO:0033036;protein localization to kinetochore#GO:0034501;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;negative regulation of chromosome separation#GO:1905819;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;negative regulation of chromosome organization#GO:2001251;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of sister chromatid segregation#GO:0033046;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;cellular process#GO:0009987;regulation of chromosome separation#GO:1905818;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;negative regulation of chromosome segregation#GO:0051985;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of cell cycle#GO:0045786;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0029997|UniProtKB=Q9W3K6 Q9W3K6 Dmel\CG2258 PTHR13357:SF1 SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN NCK-INTERACTING PROTEIN WITH SH3 DOMAIN protein-containing complex binding#GO:0044877;binding#GO:0005488 transport#GO:0006810;establishment of localization#GO:0051234;endocytosis#GO:0006897;import into cell#GO:0098657;localization#GO:0051179 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039385|UniProtKB=Q9VBK9 Q9VBK9 Dmel\CG5913 PTHR31353:SF1 FAM98 PROTEIN FAM98B catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0016726|UniProtKB=Q24154 Q24154 RpL29 PTHR12884:SF0 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202 DROME|FlyBase=FBgn0033859|UniProtKB=A1Z9G2 A1Z9G2 fand PTHR11246:SF5 PRE-MRNA SPLICING FACTOR PRE-MRNA-SPLICING FACTOR SYF1 protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0264307|UniProtKB=Q9VSR3 Q9VSR3 orb2 PTHR12566:SF19 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB TRANSLATIONAL REGULATOR ORB2 protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730;translation factor activity#GO:0180051 negative regulation of gene expression#GO:0010629;developmental process involved in reproduction#GO:0003006;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;sexual reproduction#GO:0019953;negative regulation of translation#GO:0017148;multicellular organismal reproductive process#GO:0048609;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;male gamete generation#GO:0048232;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;neuron projection#GO:0043005;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell junction#GO:0030054 mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0034629|UniProtKB=Q9W2G8 Q9W2G8 Acox57D-d PTHR10909:SF250 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE-RELATED small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;lipid binding#GO:0008289;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0031830|UniProtKB=Q9VMB9 Q9VMB9 COX5B PTHR10122:SF0 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119 transporter complex#GO:1990351;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0037531|UniProtKB=Q9VHY2 Q9VHY2 Dmel\CG10445 PTHR45626:SF50 TRANSCRIPTION TERMINATION FACTOR 2-RELATED TRANSCRIPTION TERMINATION FACTOR 2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 DROME|FlyBase=FBgn0003278|UniProtKB=P20028 P20028 Polr1B PTHR20856:SF5 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 DROME|FlyBase=FBgn0029154|UniProtKB=Q86NT5 Q86NT5 Menl-1 PTHR23406:SF101 MALIC ENZYME-RELATED MALIC ENZYME-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 DROME|FlyBase=FBgn0266581|UniProtKB=Q9VD51 Q9VD51 pit PTHR24031:SF301 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX18 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037265|UniProtKB=Q9VN45 Q9VN45 spartin PTHR21068:SF55 SPARTIN SPARTIN regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;cell division#GO:0051301;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0025864|UniProtKB=Q9W3D3 Q9W3D3 Crag PTHR12296:SF30 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN CRAG molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0261065|UniProtKB=Q9VE51 Q9VE51 Cpsf73 PTHR11203:SF11 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3 RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;RNA binding#GO:0003723;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152 intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 DROME|FlyBase=FBgn0038784|UniProtKB=Q9VDN6 Q9VDN6 Dmel\CG4362 PTHR21113:SF14 AGAP001705-PA LP24064P DROME|FlyBase=FBgn0039027|UniProtKB=Q9VCT7 Q9VCT7 Dmel\CG7031 PTHR47771:SF6 LD27203P-RELATED LP03545P DROME|FlyBase=FBgn0038144|UniProtKB=Q9VFW0 Q9VFW0 Dmel\CG8870 PTHR24260:SF144 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED Toll pathway-drosophila#P06217>SPE#P06340 DROME|FlyBase=FBgn0031465|UniProtKB=Q9VQH3 Q9VQH3 gi7295901 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED DROME|FlyBase=FBgn0039251|UniProtKB=Q9VC07 Q9VC07 Trf4-2 PTHR23092:SF15 POLY(A) RNA POLYMERASE INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0263930|UniProtKB=Q24114 Q24114 dally PTHR10822:SF29 GLYPICAN DIVISION ABNORMALLY DELAYED PROTEIN regulation of response to stimulus#GO:0048583;regulation of localization#GO:0032879;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein localization to membrane#GO:1905475;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signaling#GO:0023051;regulation of protein localization#GO:0032880;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0263929|UniProtKB=A0A0B4K682 A0A0B4K682 jvl PTHR43939:SF108 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 JAVELIN-LIKE, ISOFORM D DROME|FlyBase=FBgn0015721|UniProtKB=Q86PC9 Q86PC9 ktub PTHR16517:SF162 TUBBY-RELATED PROTEIN KING TUBBY macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to cilium#GO:0061512;localization#GO:0051179;protein localization to organelle#GO:0033365 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033860|UniProtKB=A1Z9G3 A1Z9G3 S-Lap5 PTHR11963:SF16 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0033447|UniProtKB=A1Z7Z9 A1Z7Z9 dila PTHR31540:SF1 CENTROSOMAL PROTEIN OF 131 KDA CENTROSOMAL PROTEIN OF 131 KDA cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;intraciliary transport involved in cilium assembly#GO:0035735;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;intracellular transport#GO:0046907;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;developmental process#GO:0032502;spermatogenesis#GO:0007283;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;sperm axoneme assembly#GO:0007288;male gamete generation#GO:0048232;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;intraciliary transport#GO:0042073 DROME|FlyBase=FBgn0267728|UniProtKB=Q7JXW8 Q7JXW8 otk2 PTHR10075:SF102 BASIGIN RELATED OFF-TRACK2-RELATED regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0263747|UniProtKB=Q86B52 Q86B52 CG8473 PTHR19229:SF282 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0010549|UniProtKB=P91660 P91660 l(2)03659 PTHR24223:SF448 ATP-BINDING CASSETTE SUB-FAMILY C FI20146P1-RELATED localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0038350|UniProtKB=Q9VF50 Q9VF50 AOX4 PTHR11908:SF132 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE 1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0038440|UniProtKB=Q9VEU0 Q9VEU0 Gr89a PTHR21143:SF121 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 59F-RELATED dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038277|UniProtKB=Q9VFE4 Q9VFE4 RpS5b PTHR11205:SF18 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0031530|UniProtKB=Q6WV19 Q6WV19 Pgant2 PTHR11675:SF119 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0035468|UniProtKB=Q9VZL7 Q9VZL7 Gr63a PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0032176|UniProtKB=Q9VL47 Q9VL47 Dmel\CG13127 PTHR41967:SF6 FI19406P1-RELATED FI19406P1-RELATED DROME|FlyBase=FBgn0036824|UniProtKB=Q9VVU1 Q9VVU1 GH07925p PTHR43884:SF1 ACYL-COA DEHYDROGENASE SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0037796|UniProtKB=A0A0B4KFK4 A0A0B4KFK4 Dmel\CG12814 PTHR46560:SF5 CYPHER, ISOFORM B ZP DOMAIN-CONTAINING PROTEIN anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;cell morphogenesis#GO:0000902;anatomical structure development#GO:0048856 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0030838|UniProtKB=Q9VX56 Q9VX56 Dmel\CG5445 PTHR20930:SF10 OVARIAN CARCINOMA ANTIGEN CA125-RELATED PROTEIN ILRUN negative regulation of metabolic process#GO:0009892;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;regulation of protein localization#GO:0032880;cellular localization#GO:0051641;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;protein targeting to vacuole#GO:0006623;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of localization#GO:0032879;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of multicellular organismal process#GO:0051241;localization#GO:0051179;protein localization to vacuole#GO:0072665;macroautophagy#GO:0016236;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule localization#GO:0033036;regulation of cytokine production#GO:0001817;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;vacuolar transport#GO:0007034;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;autophagosome#GO:0005776 DROME|FlyBase=FBgn0034964|UniProtKB=Q9W1C5 Q9W1C5 IntS1 PTHR21224:SF1 INTEGRATOR COMPLEX SUBUNIT 1 INTEGRATOR COMPLEX SUBUNIT 1 snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 integrator complex#GO:0032039;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0039178|UniProtKB=Q9VCA0 Q9VCA0 Dmel\CG6356 PTHR24064:SF424 SOLUTE CARRIER FAMILY 22 MEMBER FI05810P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0016930|UniProtKB=Q9V3D5 Q9V3D5 Dyrk2 PTHR24058:SF136 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0053056|UniProtKB=Q961L8 Q961L8 Targ2 PTHR12521:SF0 PROTEIN C6ORF130 ADP-RIBOSE GLYCOHYDROLASE OARD1 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;purine nucleoside metabolic process#GO:0042278;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;cellular response to stimulus#GO:0051716;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;nucleoside metabolic process#GO:0009116 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0053508|UniProtKB=Q86LG9 Q86LG9 ppk13 PTHR11690:SF175 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 13 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0038342|UniProtKB=Q9VF59 Q9VF59 B9d1 PTHR12968:SF1 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 1 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 ciliary transition zone#GO:0035869;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 structural protein#PC00211 DROME|FlyBase=FBgn0037202|UniProtKB=Q9VNP8 Q9VNP8 Ssl1 PTHR12695:SF2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transcription factor TFIIH core complex#GO:0000439;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0034834|UniProtKB=Q9W1T4 Q9W1T4 LS2 PTHR23139:SF9 RNA-BINDING PROTEIN SPLICING FACTOR U2AF 65 KDA SUBUNIT RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;binding#GO:0005488;pre-mRNA binding#GO:0036002 protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;nuclear speck#GO:0016607;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684 DROME|FlyBase=FBgn0038744|UniProtKB=Q9I7J1 Q9I7J1 PR72 PTHR14095:SF0 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED MIP22305P protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;protein-containing complex#GO:0032991 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 DROME|FlyBase=FBgn0032702|UniProtKB=Q9VJ61 Q9VJ61 Dmel\CG10376 PTHR13832:SF818 PROTEIN PHOSPHATASE 2C SD03870P catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;signaling#GO:0023052;regulation of actin filament bundle assembly#GO:0032231;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903 protein phosphatase#PC00195 DROME|FlyBase=FBgn0250841|UniProtKB=Q9VQA3 Q9VQA3 anon-SAGE:Wang-110 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036679|UniProtKB=Q9VVC2 Q9VVC2 Dmel\CG13022 PTHR10380:SF246 CUTICLE PROTEIN CUTICULAR PROTEIN 73D, ISOFORM B extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0003082|UniProtKB=Q7JY97 Q7JY97 phr PTHR10211:SF0 DEOXYRIBODIPYRIMIDINE PHOTOLYASE DEOXYRIBODIPYRIMIDINE PHOTO-LYASE deoxyribodipyrimidine photo-lyase activity#GO:0003904;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;photoreactive repair#GO:0000719;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;pyrimidine dimer repair#GO:0006290;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 lyase#PC00144 DROME|FlyBase=FBgn0011474|UniProtKB=Q9VFK6 Q9VFK6 Set8 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279 cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;chromosome organization#GO:0051276;regulation of biosynthetic process#GO:0009889;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0050488|UniProtKB=A0A0B4K7N3 A0A0B4K7N3 antr PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0013954|UniProtKB=P48375 P48375 Fkbp12 PTHR10516:SF466 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP12 catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity#GO:0003824 signaling#GO:0023052;protein folding#GO:0006457;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257;regulation of muscle contraction#GO:0006937;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;gene expression#GO:0010467;protein maturation#GO:0051604;signal transduction#GO:0007165;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of release of sequestered calcium ion into cytosol#GO:0051279;metabolic process#GO:0008152;regulation of heart contraction#GO:0008016;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;macromolecule biosynthetic process#GO:0009059;calcium-mediated signaling#GO:0019722;macromolecule metabolic process#GO:0043170;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 DROME|FlyBase=FBgn0039508|UniProtKB=Q9VB48 Q9VB48 SD09067p PTHR14387:SF0 THADA/DEATH RECEPTOR INTERACTING PROTEIN DUF2428 DOMAIN-CONTAINING PROTEIN enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0016075|UniProtKB=Q9VMV5 Q9VMV5 vkg PTHR24023:SF1137 COLLAGEN ALPHA COLLAGEN ALPHA-1(IV) CHAIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 DROME|FlyBase=FBgn0002989|UniProtKB=O76460 O76460 okr PTHR45629:SF17 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54-LIKE DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;response to stimulus#GO:0050896;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 damaged DNA-binding protein#PC00086 DROME|FlyBase=FBgn0001217|UniProtKB=P11146 P11146 Hsc70-2 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein refolding#GO:0042026;metabolic process#GO:0008152 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 DROME|FlyBase=FBgn0004865|UniProtKB=P45447 P45447 Eip78C PTHR45805:SF12 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2A C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0036764|UniProtKB=Q9VVM0 Q9VVM0 anon-WO0118547.111 PTHR43243:SF103 INNER MEMBRANE TRANSPORTER YGJI-RELATED SUBFAMILY NOT NAMED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0261439|UniProtKB=Q94523 Q94523 SdhA PTHR11632:SF51 SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;anaerobic respiration#GO:0009061 respiratory chain complex II (succinate dehydrogenase)#GO:0045273;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739 dehydrogenase#PC00092 DROME|FlyBase=FBgn0026721|UniProtKB=Q7KN04 Q7KN04 fat-spondin PTHR11311:SF23 SPONDIN SPONDIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0034202|UniProtKB=A1ZAR2 A1ZAR2 Dmel\CG17287 PTHR22883:SF511 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 cellular component organization#GO:0016043;protein targeting#GO:0006605;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;developmental maturation#GO:0021700;protein targeting to membrane#GO:0006612;developmental process#GO:0032502;establishment of localization#GO:0051234;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0263120|UniProtKB=A0A0B4KFE4 A0A0B4KFE4 Acsl PTHR43272:SF118 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;generation of neurons#GO:0048699;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521 membraneless organelle#GO:0043228;lipid droplet#GO:0005811;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 ligase#PC00142 DROME|FlyBase=FBgn0034622|UniProtKB=B7YZM8 B7YZM8 BBS9 PTHR20991:SF0 PARATHYROID HORMONE-RESPONSIVE B1 GENE PROTEIN PTHB1 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;BBSome#GO:0034464;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0035089|UniProtKB=Q9W0X2 Q9W0X2 Phk-3 PTHR11257:SF13 CHEMOSENSORY PROTEIN-RELATED GEO07322P1 DROME|FlyBase=FBgn0027507|UniProtKB=A1Z6G6 A1Z6G6 Dmel\CG1344 PTHR12984:SF15 SCY1-RELATED S/T PROTEIN KINASE-LIKE PROTEIN-ASSOCIATING WITH THE CARBOXYL-TERMINAL DOMAIN OF EZRIN non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0046704|UniProtKB=M9PCD4 M9PCD4 Liprin-alpha PTHR12587:SF20 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA, ISOFORM E structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;presynaptic active zone#GO:0048786;synapse#GO:0045202;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039498|UniProtKB=Q9VB61 Q9VB61 Dmel\CG17991 PTHR46283:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0260456|UniProtKB=Q9W124 Q9W124 Dmel\CG4806 PTHR48039:SF7 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 28 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0031010|UniProtKB=A8JUR0 A8JUR0 Dmel\CG8028 PTHR11360:SF309 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 7-LIKE PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0034740|UniProtKB=Q9W224 Q9W224 nsr PTHR11208:SF140 RNA-BINDING PROTEIN RELATED GH05812P-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0051157|UniProtKB=Q8INH8 Q8INH8 Dmel\CG31157 PTHR12459:SF6 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN DROME|FlyBase=FBgn0021765|UniProtKB=O18404 O18404 scu PTHR43658:SF15 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 steroid metabolic process#GO:0008202;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036381|UniProtKB=Q9VU95 Q9VU95 CG8745 PTHR45688:SF18 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2-LIKE DROME|FlyBase=FBgn0029996|UniProtKB=Q7JW03 Q7JW03 UbcE2H PTHR24068:SF128 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 H ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity#GO:0003824;transferase activity#GO:0016740 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 DROME|FlyBase=FBgn0031777|UniProtKB=Q9VMH7 Q9VMH7 CG9154 PTHR13200:SF0 EEF1A LYSINE METHYLTRANSFERASE 1 EEF1A LYSINE METHYLTRANSFERASE 1 lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 DROME|FlyBase=FBgn0052053|UniProtKB=Q9VT79 Q9VT79 CG6645 PTHR23529:SF2 GH19118P-RELATED GH19118P-RELATED DROME|FlyBase=FBgn0038387|UniProtKB=Q9VF08 Q9VF08 blp PTHR12388:SF0 MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16 protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle lumen#GO:0043233 transporter#PC00227 DROME|FlyBase=FBgn0033183|UniProtKB=A1Z6Z7 A1Z6Z7 Dmel\CG1620 PTHR10865:SF28 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN ELM2 DOMAIN-CONTAINING PROTEIN histone deacetylase binding#GO:0042826;protein binding#GO:0005515;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription coregulator activity#GO:0003712 negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0011211|UniProtKB=P35381 P35381 blw PTHR48082:SF2 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT ALPHA, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;ligase activity#GO:0016874;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;proton transmembrane transporter activity#GO:0015078;carbohydrate derivative binding#GO:0097367;channel activity#GO:0015267;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;proton channel activity#GO:0015252;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803 purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020 primary active transporter#PC00068;ATP synthase#PC00002 ATP synthesis#P02721>F1 alpha#P02791 DROME|FlyBase=FBgn0031893|UniProtKB=A2VEI2 A2VEI2 MICU1 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588 inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;transporter complex#GO:1990351;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0032923|UniProtKB=Q9VIF2 Q9VIF2 Pld3 PTHR10185:SF17 PHOSPHOLIPASE D - RELATED GM01519P-RELATED phospholipase#PC00186 DROME|FlyBase=FBgn0033661|UniProtKB=A8DYB0 A8DYB0 Dmel\CG13185 PTHR48103:SF2 MIDASIN-RELATED MIDASIN hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;ribosomal large subunit assembly#GO:0000027;protein-RNA complex assembly#GO:0022618;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0038578|UniProtKB=Q9VEC1 Q9VEC1 MED17 PTHR13114:SF7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0034750|UniProtKB=Q9W230 Q9W230 Dmel\CG3732 PTHR12999:SF26 ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 lipid binding#GO:0008289;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipopolysaccharide binding#GO:0001530 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0262360|UniProtKB=A0A0B4K780 A0A0B4K780 Dmel\CG43058 PTHR23041:SF83 RING FINGER DOMAIN-CONTAINING DEGRINGOLADE, ISOFORM A-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage response#GO:0006974;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA repair#GO:0006281;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0000490|UniProtKB=P07713 P07713 dpp PTHR11848:SF263 TGF-BETA FAMILY PROTEIN DECAPENTAPLEGIC signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 DPP signaling pathway#P06213>DPP#P06285;DPP-SCW signaling pathway#P06212>DPP full length#P06273;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;TGF-beta signaling pathway#P00052>TGFbeta#P01286;DPP-SCW signaling pathway#P06212>DPP#P06272;DPP signaling pathway#P06213>DPP full length#P06282 DROME|FlyBase=FBgn0037292|UniProtKB=Q9VN75 Q9VN75 plh PTHR11266:SF26 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 IP08061P intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 DROME|FlyBase=FBgn0002023|UniProtKB=M9PD53 M9PD53 Lim3 PTHR24208:SF128 LIM/HOMEOBOX PROTEIN LHX LIM3, ISOFORM G RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0264442|UniProtKB=Q24174 Q24174 ab PTHR23110:SF113 BTB DOMAIN TRANSCRIPTION FACTOR FI07618P-RELATED regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0036608|UniProtKB=Q9VV32 Q9VV32 Dmel\CG13040 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0052693|UniProtKB=Q8IRL8 Q8IRL8 Gr9a PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0046332|UniProtKB=P83101 P83101 gskt PTHR24057:SF82 GLYCOGEN SYNTHASE KINASE-3 ALPHA PROTEIN KINASE SHAGGY-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;cellular developmental process#GO:0048869;positive regulation of catabolic process#GO:0009896;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cytoskeleton organization#GO:0051493;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cell communication#GO:0007154;regulation of microtubule-based process#GO:0032886;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of signal transduction#GO:0009968;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;positive regulation of proteasomal protein catabolic process#GO:1901800;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PDGF signaling pathway#P00047>GSK3#P01153;Angiogenesis#P00005>GSK3beta#P00211;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175 DROME|FlyBase=FBgn0003231|UniProtKB=P14199 P14199 ref(2)P PTHR15090:SF8 SEQUESTOSOME 1-RELATED PROTEIN REF(2)P DROME|FlyBase=FBgn0000455|UniProtKB=Q9VG79 Q9VG79 Dip-C PTHR43226:SF1 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO DIPEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 metalloprotease#PC00153 DROME|FlyBase=FBgn0036287|UniProtKB=A8JNS0 A8JNS0 Dmel\CG10663 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0038095|UniProtKB=Q9VG17 Q9VG17 Cyp304a1 PTHR24303:SF38 HEME-BINDING MONOOXYGENASE FAMILY CYTOCHROME P450 304A1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0032479|UniProtKB=Q9VK28 Q9VK28 CT35580 PTHR24366:SF183 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LD10349P cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0011832|UniProtKB=Q9VQ97 Q9VQ97 Ser12 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033748|UniProtKB=A1Z913 A1Z913 vis PTHR11850:SF59 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0053702|UniProtKB=Q4ABI7 Q4ABI7 Dmel\CG33702 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0039136|UniProtKB=Q9VCF0 Q9VCF0 CG5902 PTHR13016:SF0 AMMECR1 HOMOLOG AMME SYNDROME CANDIDATE GENE 1 PROTEIN DROME|FlyBase=FBgn0000028|UniProtKB=P24350 P24350 acj6 PTHR11636:SF70 POU DOMAIN INHIBITORY POU PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0053914|UniProtKB=A1Z6U0 A1Z6U0 Dmel\CG33914 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0259244|UniProtKB=B7Z0K8 B7Z0K8 CG42342 PTHR24023:SF1145 COLLAGEN ALPHA COLLAGEN ALPHA CHAIN CG42342 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0028944|UniProtKB=Q9VJN9 Q9VJN9 Semp1 PTHR10127:SF914 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0264273|UniProtKB=A0A0B4KG38 A0A0B4KG38 Sema2b PTHR11036:SF90 SEMAPHORIN SEMAPHORIN-2A binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon development#GO:0061564;axon guidance#GO:0007411;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 DROME|FlyBase=FBgn0030465|UniProtKB=Q9VYF2 Q9VYF2 CG15743 PTHR43028:SF4 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL MONOPHOSPHATASE 3-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0033289|UniProtKB=B7YZU1 B7YZU1 Dmel\CG2121 PTHR19444:SF50 UNC-93 RELATED SUBFAMILY NOT NAMED channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of system process#GO:0044057;regulation of muscle contraction#GO:0006937;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;contractile muscle fiber#GO:0043292;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 DROME|FlyBase=FBgn0038567|UniProtKB=Q9VED2 Q9VED2 Dmel\CG14316 PTHR13382:SF87 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B BARD-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ATP synthase#PC00002 DROME|FlyBase=FBgn0035166|UniProtKB=Q9W0M3 Q9W0M3 JMJD5 PTHR12461:SF106 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND ARGINYL-HYDROXYLASE JMJD5 histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;chromatin binding#GO:0003682;binding#GO:0005488;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036319|UniProtKB=Q9VU20 Q9VU20 Ent3 PTHR10332:SF93 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4 carbohydrate derivative transmembrane transporter activity#GO:1901505;active transmembrane transporter activity#GO:0022804;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0027564|UniProtKB=Q9Y123 Q9Y123 CG3149 PTHR13117:SF5 ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED MAN(5)GLCNAC(2)-PP-DOLICHOL TRANSLOCATION PROTEIN RFT1 membrane organization#GO:0061024;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid transport#GO:0006869;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0040608|UniProtKB=Q9VBC1 Q9VBC1 CG32950 PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0030697|UniProtKB=Q9VXN5 Q9VXN5 Dmel\CG8565 PTHR47634:SF26 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SERINE-ARGININE PROTEIN KINASE AT 79D-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0040765|UniProtKB=Q8MR37 Q8MR37 luna PTHR23235:SF166 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR LUNA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0036053|UniProtKB=Q7KUD4 Q7KUD4 iPLA2-VIA PTHR24139:SF36 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 PHOSPHOLIPASE A2 thiolester hydrolase activity#GO:0016790;carboxylic ester hydrolase activity#GO:0052689;fatty acyl-CoA hydrolase activity#GO:0047617;lipase activity#GO:0016298;acyl-CoA hydrolase activity#GO:0016289;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;deacylase activity#GO:0160215;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;A2-type glycerophospholipase activity#GO:0004623 regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of lipid metabolic process#GO:0019216 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 lipase#PC00143;phospholipase#PC00186 DROME|FlyBase=FBgn0052112|UniProtKB=Q8IQI5 Q8IQI5 Abhd18 PTHR13617:SF14 PROTEIN ABHD18 CARDIOLIPIN-SPECIFIC DEACYLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;glycerophospholipase activity#GO:0004620 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 DROME|FlyBase=FBgn0000578|UniProtKB=Q8T4F7 Q8T4F7 ena PTHR11202:SF38 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER PROTEIN ENABLED cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;actin cytoskeleton organization#GO:0030036;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;actin filament-based process#GO:0030029;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;actin polymerization or depolymerization#GO:0008154;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502 membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;filopodium#GO:0030175;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell-substrate junction#GO:0030055;cell projection#GO:0042995;focal adhesion#GO:0005925;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0050423|UniProtKB=Q8MMD0 Q8MMD0 BcDNA:RH04491 PTHR12050:SF0 LEPTIN RECEPTOR-RELATED RH04491P cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036214|UniProtKB=Q9VTP5 Q9VTP5 Dmel\CG7264 PTHR14517:SF6 RIB43A-RELATED RE41410P cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0015664|UniProtKB=Q94883 Q94883 Dref PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0260397|UniProtKB=Q9VW97 Q9VW97 Su(var)3-3 PTHR10742:SF423 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A histone modifying activity#GO:0140993;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;histone demethylase activity#GO:0032452;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;chromatin binding#GO:0003682;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 oxidase#PC00175 DROME|FlyBase=FBgn0031401|UniProtKB=Q9VQ91 Q9VQ91 papi PTHR22948:SF83 TUDOR DOMAIN CONTAINING PROTEIN TUDOR AND KH DOMAIN-CONTAINING PROTEIN HOMOLOG scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037382|UniProtKB=Q9VNI8 Q9VNI8 Hpr1 PTHR13265:SF0 THO COMPLEX SUBUNIT 1 HPR1 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169 THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;transcription export complex#GO:0000346 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0038485|UniProtKB=Q9VEM5 Q9VEM5 Dmel\CG5255 PTHR24260:SF138 AT07769P-RELATED IP10340P-RELATED DROME|FlyBase=FBgn0036260|UniProtKB=Q9VTU7 Q9VTU7 Rh7 PTHR24229:SF106 NEUROPEPTIDES RECEPTOR GH14208P G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;neuropeptide binding#GO:0042923;peptide binding#GO:0042277 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0032228|UniProtKB=Q9VKY4 Q9VKY4 CtsL4 PTHR12411:SF1011 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0027598|UniProtKB=A0A0B4KI34 A0A0B4KI34 cindr PTHR14167:SF28 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 21 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031040|UniProtKB=Q9VWF8 Q9VWF8 Dmel\CG14210 PTHR13557:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0027617|UniProtKB=Q9XYZ6 Q9XYZ6 Ppil4 PTHR45843:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|FlyBase=FBgn0050047|UniProtKB=Q058X1 Q058X1 Dmel\CG30047 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0034802|UniProtKB=Q8T8R1 Q8T8R1 CNBP PTHR23002:SF117 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN CCHC-TYPE ZINC FINGER NUCLEIC ACID BINDING PROTEIN single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0038652|UniProtKB=Q7K3Q2 Q7K3Q2 ORE-8 PTHR42985:SF49 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH20226P symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0050344|UniProtKB=Q961H2 Q961H2 CG8054 PTHR23507:SF39 ZGC:174356 GH23453P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0028380|UniProtKB=Q9VVY4 Q9VVY4 fal PTHR11373:SF4 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE FALTEN, ISOFORM B phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 purine nucleotide catabolic process#GO:0006195;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine nucleoside triphosphate metabolic process#GO:0009144;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121 DROME|FlyBase=FBgn0029114|UniProtKB=Q9V477 Q9V477 Tollo PTHR45617:SF153 LEUCINE RICH REPEAT FAMILY PROTEIN TOLL-LIKE RECEPTOR TOLLO cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0034710|UniProtKB=Q9W275 Q9W275 Alp7 PTHR11596:SF91 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0038003|UniProtKB=Q9VGB8 Q9VGB8 Dmel\CG3916 PTHR24256:SF562 TRYPTASE-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0032047|UniProtKB=Q8T4E7 Q8T4E7 Dmel\CG13088 PTHR16134:SF18 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 17 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;regulation of circadian rhythm#GO:0042752;cellular process#GO:0009987;response to radiation#GO:0009314;macromolecule metabolic process#GO:0043170;response to external stimulus#GO:0009605;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;photoperiodism#GO:0009648;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;catabolic process#GO:0009056;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0017551|UniProtKB=Q9VM76 Q9VM76 Rca1 PTHR15493:SF9 F-BOX ONLY PROTEIN 5 AND 43 GH14043P enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of cell cycle process#GO:0010948;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;mitotic cell cycle phase transition#GO:0044772;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0037101|UniProtKB=Q8T4A3 Q8T4A3 Dmel\CG7634 PTHR21391:SF0 AT04489P-RELATED AT04489P-RELATED DROME|FlyBase=FBgn0259213|UniProtKB=A0A9F2H0X3 A0A9F2H0X3 side-II PTHR23278:SF31 SIDESTEP PROTEIN SIDESTEP II, ISOFORM C immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0011604|UniProtKB=Q24368 Q24368 Iswi PTHR10799:SF879 SNF2/RAD54 HELICASE FAMILY CHROMATIN-REMODELING COMPLEX ATPASE CHAIN ISWI nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;heterochromatin organization#GO:0070828;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 DROME|FlyBase=FBgn0031820|UniProtKB=Q9VMD0 Q9VMD0 Daxx PTHR12766:SF10 DEATH DOMAIN-ASSOCIATED PROTEIN 6 DAXX DAXX-LIKE PROTEIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037617|UniProtKB=Q9VHM7 Q9VHM7 nom PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0011290|UniProtKB=P49905 P49905 Taf12 PTHR12264:SF21 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085 RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 DROME|FlyBase=FBgn0285948|UniProtKB=P41092 P41092 RpL27A PTHR11721:SF3 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0032800|UniProtKB=Q9VIU5 Q9VIU5 Cep104 PTHR13371:SF0 GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN CENTROSOMAL PROTEIN OF 104 KDA cilium#GO:0005929;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053225|UniProtKB=A0A0B4LG43 A0A0B4LG43 Dmel\CG33225 PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0289122|UniProtKB=Q9VDY1 Q9VDY1 Ino80 PTHR45685:SF2 HELICASE SRCAP-RELATED CHROMATIN-REMODELING ATPASE INO80 hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;histone binding#GO:0042393 cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Ino80 complex#GO:0031011;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949 Wnt signaling pathway#P00057>SWI/SNF#P01435 DROME|FlyBase=FBgn0037422|UniProtKB=Q9VNN5 Q9VNN5 Osi13 PTHR21879:SF22 FI03362P-RELATED-RELATED FI03362P-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0003714|UniProtKB=P10735 P10735 tko PTHR11652:SF1 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226 ribosomal protein#PC00202 DROME|FlyBase=FBgn0032013|UniProtKB=M9PF78 M9PF78 Scgalpha PTHR10132:SF14 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER SARCOGLYCAN ALPHA, ISOFORM C plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cadherin#PC00057 DROME|FlyBase=FBgn0002709|UniProtKB=Q0KHR4 Q0KHR4 mei-218 PTHR11630:SF46 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3-RELATED ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;MCM complex#GO:0042555 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0003089|UniProtKB=Q86BJ3 Q86BJ3 pip PTHR12129:SF15 HEPARAN SULFATE 2-O-SULFOTRANSFERASE URONYL 2-SULFOTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039077|UniProtKB=Q9VCM3 Q9VCM3 Dmel\CG17380 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0040075|UniProtKB=Q9V3K3 Q9V3K3 rept PTHR11093:SF2 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 2 macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;protein-RNA complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;protein-containing complex organization#GO:0043933;regulation of biosynthetic process#GO:0009889;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular component assembly#GO:0022607;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090 ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0039331|UniProtKB=Q9VBR4 Q9VBR4 ND-49L PTHR11993:SF48 NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;oxidoreductase complex#GO:1990204;membrane#GO:0016020;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0261596|UniProtKB=Q9W229 Q9W229 RpS24 PTHR10496:SF0 40S RIBOSOMAL PROTEIN S24 40S RIBOSOMAL PROTEIN S24 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 DROME|FlyBase=FBgn0262955|UniProtKB=P08266 P08266 Polr2B PTHR20856:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0038511|UniProtKB=Q9VEJ9 Q9VEJ9 cysu PTHR11475:SF106 OXIDASE/PEROXIDASE CURLY SU peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 DROME|FlyBase=FBgn0016685|UniProtKB=Q27415 Q27415 Nlp PTHR22747:SF18 NUCLEOPLASMIN GEO09167P1-RELATED chaperone#PC00072 DROME|FlyBase=FBgn0285958|UniProtKB=Q9VTJ4 Q9VTJ4 Fuca PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;glycosyl compound catabolic process#GO:1901658 glycosidase#PC00110;hydrolase#PC00121 DROME|FlyBase=FBgn0051183|UniProtKB=Q9VF17 Q9VF17 CG11846 PTHR11920:SF335 GUANYLYL CYCLASE GUANYLATE CYCLASE lyase activity#GO:0016829;molecular transducer activity#GO:0060089;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824 cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cell communication#GO:0007154;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 lyase#PC00144;guanylate cyclase#PC00114 DROME|FlyBase=FBgn0041087|UniProtKB=Q7KGH1 Q7KGH1 wun2 PTHR10165:SF103 LIPID PHOSPHATE PHOSPHATASE FI04477P-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154;dephosphorylation#GO:0016311;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0032634|UniProtKB=Q9VJE4 Q9VJE4 Polr2J PTHR13946:SF16 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A catalytic activity, acting on RNA#GO:0140098;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0037475|UniProtKB=A0A0B4KFD8 A0A0B4KFD8 Fer1 PTHR23349:SF112 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST 48 RELATED 1, ISOFORM B transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0037624|UniProtKB=Q9I7K6 Q9I7K6 Nasp PTHR15081:SF1 NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED NUCLEAR AUTOANTIGENIC SPERM PROTEIN histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;kinetochore organization#GO:0051383;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 chaperone#PC00072 DROME|FlyBase=FBgn0023513|UniProtKB=O46089 O46089 CG14803 PTHR28547:SF1 PROTEIN MMS22-LIKE PROTEIN MMS22-LIKE nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0039778|UniProtKB=Q9VA66 Q9VA66 Jon99Fi PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0287182|UniProtKB=Q7PLL6 Q7PLL6 l(3)80Fj PTHR23346:SF7 TRANSLATIONAL ACTIVATOR GCN1-RELATED STALLED RIBOSOME SENSOR GCN1 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 post-transcriptional regulation of gene expression#GO:0010608;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;response to nutrient levels#GO:0031667;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;cellular process#GO:0009987;cellular response to amino acid starvation#GO:0034198;biological regulation#GO:0065007;cellular response to stress#GO:0033554;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038465|UniProtKB=Q9VEP8 Q9VEP8 Irc PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 DROME|FlyBase=FBgn0053928|UniProtKB=Q4ABF1 Q4ABF1 Dmel\CG33928 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0032248|UniProtKB=Q9VKV8 Q9VKV8 Bug22 PTHR12458:SF11 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular component organization#GO:0016043;cilium assembly#GO:0060271;anatomical structure morphogenesis#GO:0009653;sperm motility#GO:0097722;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;multicellular organism development#GO:0007275;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;spermatogenesis#GO:0007283;developmental process#GO:0032502 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 DROME|FlyBase=FBgn0039305|UniProtKB=Q9VBU4 Q9VBU4 Dmel\CG11858 PTHR45995:SF1 FAMILY NOT NAMED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 4 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034429|UniProtKB=A1ZBI9 A1ZBI9 AANATL4 PTHR20905:SF33 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 transferase#PC00220;acetyltransferase#PC00038 DROME|FlyBase=FBgn0033309|UniProtKB=Q7K2N0 Q7K2N0 Lnpk PTHR22166:SF12 ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK cellular component organization#GO:0016043;organelle organization#GO:0006996;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786;endomembrane system organization#GO:0010256 endoplasmic reticulum tubular network#GO:0071782;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0031100|UniProtKB=Q9VR83 Q9VR83 CT3673 PTHR46473:SF24 GH08155P CONNECTIN-LIKE PROTEIN DROME|FlyBase=FBgn0034197|UniProtKB=A1ZAQ7 A1ZAQ7 Cda9 PTHR45985:SF13 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 9, ISOFORM A DROME|FlyBase=FBgn0032876|UniProtKB=Q9VIK6 Q9VIK6 Cen PTHR19232:SF7 CENTROCORTIN FAMILY MEMBER CENTROCORTIN, ISOFORM A DROME|FlyBase=FBgn0262117|UniProtKB=Q7PLS8 Q7PLS8 IntS3 PTHR13587:SF7 INTEGRATOR COMPLEX SUBUNIT 3 INTEGRATOR COMPLEX SUBUNIT 3 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0266100|UniProtKB=X2JCU8 X2JCU8 CG5917 PTHR10443:SF49 MICROSOMAL DIPEPTIDASE DIPEPTIDASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0011695|UniProtKB=Q9W1C9 Q9W1C9 EbpIII PTHR11257:SF12 CHEMOSENSORY PROTEIN-RELATED EJACULATORY BULB-SPECIFIC PROTEIN 3-RELATED DROME|FlyBase=FBgn0038873|UniProtKB=Q9VDC5 Q9VDC5 Dmel\CG5892 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0054010|UniProtKB=Q2PDV0 Q2PDV0 Glyat PTHR20958:SF10 GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN GH05617P-RELATED DROME|FlyBase=FBgn0036301|UniProtKB=Q9VTZ7 Q9VTZ7 anon-WO0172774.58 PTHR46063:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 4 DROME|FlyBase=FBgn0259821|UniProtKB=H1UUM0 H1UUM0 CG42402-RC PTHR46780:SF21 PROTEIN EVA-1 D-GALACTOSIDE-SPECIFIC LECTIN ISOFORM X1-RELATED DROME|FlyBase=FBgn0003357|UniProtKB=C0HKF8 C0HKF8 Jon99Ciii PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0031513|UniProtKB=Q9VQN2 Q9VQN2 Dmel\CG3347 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708 DROME|FlyBase=FBgn0052683|UniProtKB=Q9W2V2 Q9W2V2 CG15303 PTHR11792:SF18 ARRESTIN FI20035P1 binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;receptor internalization#GO:0031623;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;transport#GO:0006810;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;localization#GO:0051179;regulation of signaling#GO:0023051;nervous system process#GO:0050877;sensory perception#GO:0007600;negative regulation of signaling#GO:0023057 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032955|UniProtKB=Q8IMF4 Q8IMF4 Dmel\CG2201 PTHR22603:SF36 CHOLINE/ETHANOALAMINE KINASE CHOLINE KINASE ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;phosphatidylcholine biosynthetic process#GO:0006656;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137 DROME|FlyBase=FBgn0038258|UniProtKB=Q9VFG4 Q9VFG4 Pykl3 PTHR11817:SF3 PYRUVATE KINASE AT14039P-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;pyruvate kinase activity#GO:0004743;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 DROME|FlyBase=FBgn0052380|UniProtKB=Q9VS60 Q9VS60 SMSr PTHR21290:SF69 SPHINGOMYELIN SYNTHETASE SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0040321|UniProtKB=Q9NHA8 Q9NHA8 GNBP3 PTHR10963:SF70 GLYCOSYL HYDROLASE-RELATED GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glucosidase#PC00108 DROME|FlyBase=FBgn0003861|UniProtKB=P19334 P19334 trp PTHR10117:SF51 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL PROTEIN calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;regulation of cytosolic calcium ion concentration#GO:0051480;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 DROME|FlyBase=FBgn0037379|UniProtKB=Q9VNI5 Q9VNI5 Dmel\CG10979 PTHR21020:SF0 ZINC FINGER PROTEIN 800 ZINC FINGER PROTEIN 800 DROME|FlyBase=FBgn0031540|UniProtKB=Q9VQR3 Q9VQR3 Pif1 PTHR23274:SF11 DNA HELICASE-RELATED ATP-DEPENDENT DNA HELICASE PIF1 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678 DNA helicase#PC00011 DROME|FlyBase=FBgn0032900|UniProtKB=M9NDC5 M9NDC5 Dmel\CG14401 PTHR33562:SF18 ATILLA, ISOFORM B-RELATED-RELATED RE19849P-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0031585|UniProtKB=Q9VQX0 Q9VQX0 Dmel\CG2955 PTHR10623:SF6 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER EB1, ISOFORM F-RELATED microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein localization to cytoskeleton#GO:0044380;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;intracellular protein localization#GO:0008104;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;protein localization to microtubule cytoskeleton#GO:0072698;cellular component assembly#GO:0022607 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule end#GO:1990752;cytoplasmic microtubule#GO:0005881 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0052819|UniProtKB=Q8I0K9 Q8I0K9 Dmel\CG32820 PTHR19960:SF11 TEKTIN LD08455P cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0032421|UniProtKB=Q9VKA0 Q9VKA0 crok PTHR33562:SF32 ATILLA, ISOFORM B-RELATED-RELATED GEO08323P1-RELATED DROME|FlyBase=FBgn0052086|UniProtKB=Q8IQG0 Q8IQG0 CG6100 PTHR12086:SF12 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;sperm motility#GO:0097722;regulation of calcium-mediated signaling#GO:0050848;reproductive process#GO:0022414;regulation of cell communication#GO:0010646;regulation of metal ion transport#GO:0010959;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;regulation of calcineurin-NFAT signaling cascade#GO:0070884;cilium movement involved in cell motility#GO:0060294;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;regulation of response to stimulus#GO:0048583;flagellated sperm motility#GO:0030317;regulation of transport#GO:0051049;regulation of localization#GO:0032879;microtubule-based process#GO:0007017 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0034240|UniProtKB=A1ZAV3 A1ZAV3 MESR4 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0002531|UniProtKB=P02839 P02839 Lcp1 PTHR10380:SF230 CUTICLE PROTEIN CUTICULAR PROTEIN 47EE-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0039114|UniProtKB=Q9VCI3 Q9VCI3 Lsd-1 PTHR14024:SF49 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cellular process#GO:0009987;lipid storage#GO:0019915;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of localization#GO:0032879 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035476|UniProtKB=Q9VZK8 Q9VZK8 Ar6 PTHR11732:SF385 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0019686|UniProtKB=O61267 O61267 lok PTHR44167:SF39 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE_THREONINE-PROTEIN KINASE CHK2 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway#P00059>Chk2#P01484 DROME|FlyBase=FBgn0023416|UniProtKB=Q9V9R3 Q9V9R3 Ac3 PTHR45627:SF30 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 3 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0031633|UniProtKB=Q9VR31 Q9VR31 Fnta PTHR11129:SF1 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0039486|UniProtKB=Q9VB76 Q9VB76 CAH9 PTHR18952:SF137 CARBONIC ANHYDRASE CARBONIC ANHYDRASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0027512|UniProtKB=Q9XZ32 Q9XZ32 Dmel\CG10254 PTHR46116:SF51 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0028517|UniProtKB=Q7KT71 Q7KT71 Dmel\CG31827 PTHR24256:SF462 TRYPTASE-RELATED LP21446P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0029002|UniProtKB=M9PDI0 M9PDI0 miple2 PTHR21050:SF1 MIDKINE AND PLEIOTROPHIN 1, ISOFORM A-RELATED MIDKINE AND PLEIOTROPHIN 1, ISOFORM A-RELATED heparin binding#GO:0008201;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;mesoderm development#GO:0007498;tissue morphogenesis#GO:0048729;mesoderm morphogenesis#GO:0048332;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037213|UniProtKB=Q9VMY3 Q9VMY3 Dmel\CG12581 PTHR21219:SF3 FI19613P1 FI19613P1 DROME|FlyBase=FBgn0039678|UniProtKB=Q9VAJ4 Q9VAJ4 Obp99a PTHR11857:SF46 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 99A-RELATED sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0016054|UniProtKB=Q0E8P0 Q0E8P0 phr6-4 PTHR11455:SF9 CRYPTOCHROME CRYPTOCHROME CIRCADIAN REGULATOR 5 nucleotide binding#GO:0000166;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;deoxyribodipyrimidine photo-lyase activity#GO:0003904;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleic acid binding#GO:0003676;ion binding#GO:0043167;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleoside phosphate binding#GO:1901265 DNA photolyase#PC00014 Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501;Circadian clock system#P00015>Cry#P00505 DROME|FlyBase=FBgn0026602|UniProtKB=Q7JWW6 Q7JWW6 Adk3 PTHR45769:SF5 ADENOSINE KINASE ADENOSINE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773 small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 DROME|FlyBase=FBgn0034177|UniProtKB=Q7JZR5 Q7JZR5 AsnRS-m PTHR22594:SF59 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINYL-TRNA SYNTHETASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0034568|UniProtKB=Q8MLX0 Q8MLX0 Dmel\CG3216 PTHR11920:SF274 GUANYLYL CYCLASE GUANYLATE CYCLASE lyase activity#GO:0016829;molecular transducer activity#GO:0060089;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824 signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 lyase#PC00144;guanylate cyclase#PC00114 DROME|FlyBase=FBgn0037326|UniProtKB=Q9VNB7 Q9VNB7 Q9VNB7 PTHR46350:SF2 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS-LIKE PROTEIN FAMILY MEMBER 10B DROME|FlyBase=FBgn0032713|UniProtKB=Q9VJ46 Q9VJ46 Ugt36D1 PTHR48043:SF114 EG:EG0003.4 PROTEIN-RELATED IP04436P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0085443|UniProtKB=Q8MQW8 Q8MQW8 spri PTHR23101:SF104 RAB GDP/GTP EXCHANGE FACTOR PROTEIN SPRINT protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytosol#GO:0005829;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0029502|UniProtKB=Q9W3W4 Q9W3W4 Coq7 PTHR11237:SF6 COENZYME Q10 BIOSYNTHESIS PROTEIN 7 NADPH-DEPENDENT 3-DEMETHOXYUBIQUINONE 3-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;biological regulation#GO:0065007;ketone metabolic process#GO:0042180;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;regulation of biological process#GO:0050789;ubiquinone biosynthetic process#GO:0006744;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;regulation of reactive oxygen species metabolic process#GO:2000377 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0031640|UniProtKB=Q9VR38 Q9VR38 Mon1 PTHR13027:SF19 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;transport#GO:0006810;vacuolar transport#GO:0007034 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;late endosome#GO:0005770;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0000212|UniProtKB=P25439 P25439 brm PTHR10799:SF973 SNF2/RAD54 HELICASE FAMILY BRAHMA CHROMATIN-REMODELING COMPLEX ATPASE SUBUNIT chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 DROME|FlyBase=FBgn0035623|UniProtKB=Q9VRN2 Q9VRN2 mthl2 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0004512|UniProtKB=Q00449 Q00449 Mdr49 PTHR24221:SF503 ATP-BINDING CASSETTE SUB-FAMILY B MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49-RELATED primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0032061|UniProtKB=Q9VLI6 Q9VLI6 CatB PTHR11465:SF9 CATALASE CATALASE heme binding#GO:0020037;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity#GO:0016491;binding#GO:0005488;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;tetrapyrrole binding#GO:0046906 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to oxygen-containing compound#GO:1901700;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;response to stress#GO:0006950;cellular process#GO:0009987;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to chemical#GO:0042221;hydrogen peroxide metabolic process#GO:0042743 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 peroxidase#PC00180 DROME|FlyBase=FBgn0086357|UniProtKB=Q8STG9 Q8STG9 Sec61alpha PTHR10906:SF1 SECY/SEC61-ALPHA FAMILY MEMBER DSEC61ALPHA binding#GO:0005488;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ribonucleoprotein complex binding#GO:0043021;transmembrane protein transporter activity#GO:0008320;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization within membrane#GO:0051668 rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum#GO:0005791;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0011476|UniProtKB=Q9VF98 Q9VF98 l(3)neo43 PTHR17130:SF14 MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038912|UniProtKB=Q9VD68 Q9VD68 Dmel\CG6656 PTHR11567:SF19 ACID PHOSPHATASE-RELATED GH19849P hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phosphatase#PC00181 DROME|FlyBase=FBgn0053111|UniProtKB=Q9VCH2 Q9VCH2 CG11945 PTHR46606:SF5 SHOOTIN-1 FI03658P neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of neuron migration#GO:2001222;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;cellular developmental process#GO:0048869;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154 intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;axon#GO:0030424;growth cone#GO:0030426;axonal growth cone#GO:0044295;cell projection#GO:0042995;distal axon#GO:0150034;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell leading edge#GO:0031252 DROME|FlyBase=FBgn0036926|UniProtKB=Q9VW66 Q9VW66 Dmel\CG7646 PTHR23055:SF69 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 calmodulin-related#PC00061 DROME|FlyBase=FBgn0036250|UniProtKB=Q9VTT6 Q9VTT6 Ir68b PTHR42643:SF47 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 68B-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0038952|UniProtKB=Q9VD23 Q9VD23 Pykl1 PTHR11817:SF3 PYRUVATE KINASE AT14039P-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773 purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 DROME|FlyBase=FBgn0005677|UniProtKB=Q8IP19 Q8IP19 dac PTHR12577:SF6 DACHSHUND DACHSHUND, ISOFORM B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0053098|UniProtKB=Q9VG88 Q9VG88 CT39356 PTHR23049:SF68 MYOSIN REGULATORY LIGHT CHAIN 2 MIP03207P cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488;protein binding#GO:0005515 post-embryonic development#GO:0009791;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0035070|UniProtKB=Q9W0Z7 Q9W0Z7 SP159 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0031118|UniProtKB=X2JEI9 X2JEI9 RhoGAP19D PTHR23176:SF139 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE ACTIVATING PROTEIN AT 19D, ISOFORM D molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0265784|UniProtKB=Q9VWW0 Q9VWW0 CrebB PTHR45879:SF3 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;regulation of nucleobase-containing compound metabolic process#GO:0019219 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 DROME|FlyBase=FBgn0050296|UniProtKB=Q9W2N4 Q9W2N4 RIC-3 PTHR21723:SF6 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3 RIC3 ACETYLCHOLINE RECEPTOR CHAPERONE, ISOFORM C trans-synaptic signaling#GO:0099537;intracellular protein localization#GO:0008104;cell communication#GO:0007154;localization#GO:0051179;cellular process#GO:0009987;regulation of biological process#GO:0050789;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;macromolecule localization#GO:0033036;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;anterograde trans-synaptic signaling#GO:0098916;synaptic transmission, cholinergic#GO:0007271 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection#GO:0043005 DROME|FlyBase=FBgn0042085|UniProtKB=A1Z6M0 A1Z6M0 Bap170 PTHR22970:SF14 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949 DROME|FlyBase=FBgn0041094|UniProtKB=Q9VTH4 Q9VTH4 scyl PTHR12478:SF16 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 PROTEIN CHARYBDE-RELATED regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915;regulation of TOR signaling#GO:0032006;cell death#GO:0008219;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 DROME|FlyBase=FBgn0031099|UniProtKB=Q9VR81 Q9VR81 CG17065 PTHR11113:SF14 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;amino sugar catabolic process#GO:0046348;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;deacetylase#PC00087 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 DROME|FlyBase=FBgn0038194|UniProtKB=Q9VFP1 Q9VFP1 Cyp6d5 PTHR24292:SF93 CYTOCHROME P450 CYTOCHROME P450 310A1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0026369|UniProtKB=Q7K9H6 Q7K9H6 Sara PTHR46319:SF3 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 MYO signaling pathway#P06215>SARA#P06313;Activin beta signaling pathway#P06210>SARA#P06235;ALP23B signaling pathway#P06209>SARA#P06222;TGF-beta signaling pathway#P00052>SARA#P01281 DROME|FlyBase=FBgn0004618|UniProtKB=P13360 P13360 gl PTHR23226:SF442 ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN GLASS DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0032692|UniProtKB=Q9VJ72 Q9VJ72 IFT46 PTHR13376:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0029824|UniProtKB=X2JDV1 X2JDV1 Dmel\CG3726 PTHR23110:SF104 BTB DOMAIN TRANSCRIPTION FACTOR MATERNAL GENE REQUIRED FOR MEIOSIS, ISOFORM H biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0033879|UniProtKB=Q7JR58 Q7JR58 Echs1 PTHR11941:SF179 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE, MITOCHONDRIAL primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034215|UniProtKB=Q9V813 Q9V813 Mtap PTHR42679:SF2 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Purine metabolism#P02769>Nucleoside Phosphorylase#P03115 DROME|FlyBase=FBgn0040234|UniProtKB=M9PHH0 M9PHH0 c12.2 PTHR21610:SF9 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0038446|UniProtKB=Q9VET3 Q9VET3 Dmel\CG14903 PTHR46194:SF1 PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED DROME|FlyBase=FBgn0267972|UniProtKB=Q9VQ57 Q9VQ57 Der-1 PTHR11009:SF1 DER1-LIKE PROTEIN, DERLIN DERLIN-1 biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0016672|UniProtKB=Q9VFP6 Q9VFP6 Ipp PTHR43028:SF3 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL POLYPHOSPHATE 1-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;cellular process#GO:0009987;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0036986|UniProtKB=Q9VPG0 Q9VPG0 Dmel\CG5282 PTHR10443:SF21 MICROSOMAL DIPEPTIDASE DIPEPTIDASE peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0262740|UniProtKB=Q9VYY9 Q9VYY9 Evi5 PTHR22957:SF497 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN ECOTROPIC VIRAL INTEGRATION SITE 5 ORTHOLOG molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0030358|UniProtKB=Q9VYR9 Q9VYR9 Pdzd8 PTHR21519:SF1 PDZ DOMAIN-CONTAINING PROTEIN 8 PDZ DOMAIN-CONTAINING PROTEIN 8 intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane contact site#GO:0044232 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0001320|UniProtKB=P10734 P10734 kni PTHR48092:SF9 KNIRPS-RELATED PROTEIN-RELATED KNIRPS-RELATED PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0033021|UniProtKB=Q7K4Q5 Q7K4Q5 CG10417 PTHR13832:SF803 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE CG10417-RELATED catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 protein phosphatase#PC00195 DROME|FlyBase=FBgn0036289|UniProtKB=Q9VTY1 Q9VTY1 Dmel\CG10657 PTHR10174:SF166 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED LD40136P phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0035317|UniProtKB=Q9W040 Q9W040 Oseg2 PTHR15722:SF2 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782 microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 DROME|FlyBase=FBgn0000625|UniProtKB=Q9VTX7 Q9VTX7 eyg PTHR45636:SF56 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED EYEGONE, ISOFORM A-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0034791|UniProtKB=Q9W1Y1 Q9W1Y1 EMC8-9 PTHR12941:SF10 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8_9 HOMOLOG membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;protein localization to organelle#GO:0033365;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;membrane organization#GO:0061024;endomembrane system organization#GO:0010256 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 DROME|FlyBase=FBgn0037881|UniProtKB=Q9VGR1 Q9VGR1 GCC88 PTHR23157:SF25 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0035312|UniProtKB=Q9W045 Q9W045 BcDNA:SD08776 PTHR43329:SF4 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 DROME|FlyBase=FBgn0003285|UniProtKB=Q08180 Q08180 rst PTHR11640:SF170 NEPHRIN IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0033381|UniProtKB=Q7JVI6 Q7JVI6 GstE13 PTHR43969:SF8 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE E13, ISOFORM A-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364 glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0039635|UniProtKB=Q7K5K3 Q7K5K3 Pdhb PTHR11624:SF116 DEHYDROGENASE RELATED PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;generation of precursor metabolites and energy#GO:0006091;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084 oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0015904|UniProtKB=Q24248 Q24248 ara PTHR11211:SF40 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN ARAUCAN-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0038803|UniProtKB=Q9I7I6 Q9I7I6 Dmel\CG5191 PTHR43372:SF2 FATTY-ACID AMIDE HYDROLASE IP13792P hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0027549|UniProtKB=Q9Y109 Q9Y109 Nulp1 PTHR22684:SF0 NULP1-RELATED RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0260859|UniProtKB=Q9VSY8 Q9VSY8 Bet3 PTHR13048:SF0 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031995|UniProtKB=Q9VLS1 Q9VLS1 CG8475 PTHR10749:SF8 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 DROME|FlyBase=FBgn0030623|UniProtKB=Q9VXX1 Q9VXX1 PPYR1 PTHR12299:SF17 HYALURONIC ACID-BINDING PROTEIN 4 AT19571P-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0033369|UniProtKB=A1Z7N0 A1Z7N0 Dmel\CG8197 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0051516|UniProtKB=Q8I0K2 Q8I0K2 Dmel\CG31516 PTHR36299:SF4 AGAP008005-PA GH07892P-RELATED DROME|FlyBase=FBgn0000032|UniProtKB=Q8I0P9 Q8I0P9 Acph-1 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 phosphatase#PC00181 DROME|FlyBase=FBgn0013347|UniProtKB=P52656 P52656 TfIIA-S PTHR10966:SF0 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 protein binding#GO:0005515;binding#GO:0005488;transcription factor binding#GO:0008134 biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 DROME|FlyBase=FBgn0000043|UniProtKB=P02572 P02572 Act42A PTHR11937:SF607 ACTIN ACTIN-42A-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cytoskeleton-dependent cytokinesis#GO:0061640;cortical actin cytoskeleton organization#GO:0030866;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Huntington disease#P00029>Actin#P00807 DROME|FlyBase=FBgn0040907|UniProtKB=Q9W4L1 Q9W4L1 mRpL33 PTHR47037:SF1 39S RIBOSOMAL PROTEIN L33, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL33M intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 DROME|FlyBase=FBgn0025825|UniProtKB=Q7KTS4 Q7KTS4 HDAC3 PTHR10625:SF36 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 3 catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;histone modifying activity#GO:0140993;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>Histone deacetylase#P01472 DROME|FlyBase=FBgn0038972|UniProtKB=Q9VD02 Q9VD02 Dmel\CG7054 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 DROME|FlyBase=FBgn0259876|UniProtKB=A1Z987 A1Z987 Cap-G PTHR14418:SF5 CONDENSIN COMPLEX SUBUNIT 3-RELATED CONDENSIN COMPLEX SUBUNIT 3 mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;organelle fission#GO:0048285;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996 chromosome#GO:0005694;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;condensin complex#GO:0000796;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0027561|UniProtKB=A1Z7Q5 A1Z7Q5 CG30347 PTHR13196:SF14 DENN DOMAIN-CONTAINING UDENN DOMAIN-CONTAINING PROTEIN phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;localization#GO:0051179;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0243514|UniProtKB=Q9VB78 Q9VB78 eater PTHR24047:SF29 FI01909P-RELATED EATER-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0029897|UniProtKB=Q9W3W8 Q9W3W8 RpL17 PTHR11593:SF10 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202 DROME|FlyBase=FBgn0045479|UniProtKB=P83293 P83293 Gr64a PTHR21421:SF34 GUSTATORY RECEPTOR GUSTATORY RECEPTOR FOR SUGAR TASTE 61A-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888;channel activity#GO:0015267;molecular transducer activity#GO:0060089 sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;system process#GO:0003008 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0000173|UniProtKB=P35128 P35128 ben PTHR24068:SF141 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;cellular process#GO:0009987;response to stress#GO:0006950;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Ubc13#P01381 DROME|FlyBase=FBgn0267977|UniProtKB=Q9VXU6 Q9VXU6 mh PTHR21220:SF0 DNA-DEPENDENT METALLOPROTEASE SPRTN DNA-DEPENDENT METALLOPROTEASE SPRTN metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0087012|UniProtKB=Q8IPN2 Q8IPN2 5-HT2A PTHR24247:SF228 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE (SEROTONIN) RECEPTOR 2A, ISOFORM B neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 dendrite#GO:0030425;dendritic tree#GO:0097447;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 DROME|FlyBase=FBgn0034804|UniProtKB=A0A0B4KFG3 A0A0B4KFG3 GrlHz PTHR38337:SF1 AGAP010540-PA GUSTATORY RECEPTOR-LIKE HOLOZOA, ISOFORM C DROME|FlyBase=FBgn0086677|UniProtKB=Q95NU8 Q95NU8 jeb PTHR21105:SF0 GH16255P GH16255P protein kinase activator activity#GO:0030295;signaling receptor regulator activity#GO:0030545;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;signaling receptor activator activity#GO:0030546;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 neuron projection#GO:0043005;presynapse#GO:0098793;cell projection#GO:0042995;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cellular anatomical structure#GO:0110165;synapse#GO:0045202;axon#GO:0030424;axon terminus#GO:0043679;cell junction#GO:0030054 DROME|FlyBase=FBgn0014135|UniProtKB=Q9VDT9 Q9VDT9 bnl PTHR11486:SF148 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0033717|UniProtKB=Q7K2E1 Q7K2E1 Dmel\CG8839 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0033653|UniProtKB=Q1WWB7 Q1WWB7 betaG PTHR19854:SF1 TRANSDUCIN BETA-LIKE 3 GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036696|UniProtKB=Q9VVE0 Q9VVE0 Pop5 PTHR48414:SF1 POP5 HOMOLOG, RIBONUCLEASE P_MRP SUBUNIT RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;multimeric ribonuclease P complex#GO:0030681;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolar ribonuclease P complex#GO:0005655;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0035980|UniProtKB=Q9VSW4 Q9VSW4 mRRF1 PTHR20982:SF14 RIBOSOME RECYCLING FACTOR RIBOSOME-RECYCLING FACTOR, MITOCHONDRIAL binding#GO:0005488;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021 cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;mitochondrial gene expression#GO:0140053;translational termination#GO:0006415;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 translation release factor#PC00225 DROME|FlyBase=FBgn0035111|UniProtKB=Q8IRJ7 Q8IRJ7 Dis3l2 PTHR23355:SF68 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 exoribonuclease#PC00099 DROME|FlyBase=FBgn0053282|UniProtKB=Q9VQP0 Q9VQP0 CG15407 PTHR48021:SF33 FAMILY NOT NAMED AT22075P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037207|UniProtKB=Q9VNP3 Q9VNP3 Mes2 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036759|UniProtKB=Q8SXC0 Q8SXC0 Dmel\CG5577 PTHR19288:SF93 4-NITROPHENYLPHOSPHATASE-RELATED FI11325P-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0027085|UniProtKB=Q9VZ82 Q9VZ82 LeuRS-m PTHR43740:SF3 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translation#GO:0006412;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0262719|UniProtKB=Q9VSK6 Q9VSK6 CG6915 PTHR10098:SF108 RAPSYN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 28 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0025809|UniProtKB=Q9VXP4 Q9VXP4 Paf-AHalpha PTHR11852:SF0 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA HOMOLOG protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0014454|UniProtKB=Q26416 Q26416 Acp1 PTHR12336:SF0 ADULT CUTICLE PROTEIN 1-RELATED ADULT CUTICLE PROTEIN 1-RELATED DROME|FlyBase=FBgn0051742|UniProtKB=Q8INY4 Q8INY4 Prosbeta5R2 PTHR11599:SF246 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0038610|UniProtKB=Q9VE80 Q9VE80 Dmel\CG7675 PTHR24320:SF294 RETINOL DEHYDROGENASE NADP-RETINOL DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;hormone metabolic process#GO:0042445;biological regulation#GO:0065007 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0003209|UniProtKB=Q9VLI4 Q9VLI4 raw PTHR36300:SF1 RAW, ISOFORM A RAW, ISOFORM A membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0035400|UniProtKB=Q6NLL3 Q6NLL3 Dmel\CG11537 PTHR23504:SF1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 GH21943P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0025878|UniProtKB=Q9W260 Q9W260 wrapper PTHR45080:SF4 CONTACTIN 5 GH03113P signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424 DROME|FlyBase=FBgn0039188|UniProtKB=Q8SZ63 Q8SZ63 Golgin84 PTHR13815:SF7 GOLGIN-84 GOLGIN SUBFAMILY A MEMBER 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;retrograde transport, vesicle recycling within Golgi#GO:0000301;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 Golgi stack#GO:0005795;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0033382|UniProtKB=A1Z7Q7 A1Z7Q7 Hydr1 PTHR10794:SF98 ABHYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE 1, ISOFORM A carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610 serine protease#PC00203;protease#PC00190 DROME|FlyBase=FBgn0261988|UniProtKB=P32866 P32866 Gprk2 PTHR24355:SF28 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840 DROME|FlyBase=FBgn0039204|UniProtKB=Q9VC66 Q9VC66 Dmel\CG6607 PTHR21448:SF0 SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0037525|UniProtKB=A8JQV3 A8JQV3 Dmel\CG17816 PTHR32078:SF2 NUCLEAR PROTEIN MDM1 NUCLEAR PROTEIN MDM1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriolar satellite#GO:0034451;centriole#GO:0005814;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0030474|UniProtKB=Q9VYE3 Q9VYE3 Dmel\CG15747 PTHR31938:SF4 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 DROME|FlyBase=FBgn0051718|UniProtKB=M9PCT4 M9PCT4 Ir31a PTHR42643:SF32 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 31A, ISOFORM C-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0015570|UniProtKB=Q961N0 Q961N0 alpha-Est2 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0052576|UniProtKB=Q59E43 Q59E43 anon-AE003501.1 PTHR21493:SF254 CGI-141-RELATED/LIPASE CONTAINING PROTEIN GOLGI TRANSPORT PROTEIN 1-RELATED membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0035981|UniProtKB=Q9VSW7 Q9VSW7 anon-WO0172774.118 PTHR46176:SF1 LD21662P LD21662P DROME|FlyBase=FBgn0034093|UniProtKB=Q8MRB2 Q8MRB2 Dmel\CG15706 PTHR16172:SF37 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE RE36877P membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033958|UniProtKB=A1Z9U2 A1Z9U2 jef PTHR16172:SF2 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE JET FUEL, ISOFORM A membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028644|UniProtKB=Q9VJM4 Q9VJM4 beat-Ic PTHR21261:SF8 BEAT PROTEIN BEATEN PATH IA, ISOFORM B-RELATED system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0041709|UniProtKB=Q9W029 Q9W029 yellow-g PTHR10009:SF6 PROTEIN YELLOW-RELATED FI16876P1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0030752|UniProtKB=Q9VXG0 Q9VXG0 Cdc50 PTHR10926:SF0 CELL CYCLE CONTROL PROTEIN 50 CELL DIVISION CYCLE 50, ISOFORM A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0036812|UniProtKB=Q9VVS5 Q9VVS5 Nufip PTHR13309:SF0 NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1 FMR1-INTERACTING PROTEIN NUFIP1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034430|UniProtKB=Q7K159 Q7K159 mip40 PTHR31336:SF3 LIN37 HOMOLOG PROTEIN LIN-37 HOMOLOG negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0052813|UniProtKB=A0A6H2EFE9 A0A6H2EFE9 anon-WO0153538.75 PTHR21411:SF0 APONTIC REGULATORY PROTEIN ZESTE DROME|FlyBase=FBgn0038357|UniProtKB=Q8T485 Q8T485 Dmel\CG5623 PTHR21644:SF0 AT02555P-RELATED AT02555P-RELATED DROME|FlyBase=FBgn0034532|UniProtKB=A1ZBX0 A1ZBX0 Dmel\CG13436 PTHR21442:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 regulation of microtubule-based process#GO:0032886;regulation of biological process#GO:0050789;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929 DROME|FlyBase=FBgn0260938|UniProtKB=Q9VXM5 Q9VXM5 tay PTHR13585:SF19 CHASCON, ISOFORM D-RELATED CHASCON, ISOFORM D-RELATED DROME|FlyBase=FBgn0030662|UniProtKB=Q7KUZ9 Q7KUZ9 Chsy PTHR12369:SF11 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0036574|UniProtKB=Q86BP6 Q86BP6 elg1 PTHR23389:SF21 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0085488|UniProtKB=A8DYG7 A8DYG7 CG6301 PTHR37161:SF2 HDC10475 AT11648P-RELATED DROME|FlyBase=FBgn0035270|UniProtKB=Q9W089 Q9W089 Dmel\CG13933 PTHR24182:SF13 ANKYRIN REPEAT AND SOCS BOX CONTAINING 4 LD18443P DROME|FlyBase=FBgn0001169|UniProtKB=Q02308 Q02308 H PTHR23353:SF23 RAB-GAP/TBC-RELATED PROTEIN HAIRLESS GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0284254|UniProtKB=Q7K0Q2 Q7K0Q2 Impbeta11 PTHR10997:SF7 IMPORTIN-7, 8, 11 IMPORTIN-11 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365 cytosol#GO:0005829;organelle envelope#GO:0031967;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 DROME|FlyBase=FBgn0031662|UniProtKB=Q9VMW8 Q9VMW8 CG3792 PTHR12226:SF5 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN oligosaccharide biosynthetic process#GO:0009312;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;primary metabolic process#GO:0044238;cellular process#GO:0009987 DROME|FlyBase=FBgn0036461|UniProtKB=A4IJ72 A4IJ72 Zip71B PTHR12191:SF31 SOLUTE CARRIER FAMILY 39 IP18018P metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;bicarbonate transmembrane transporter activity#GO:0015106;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0036538|UniProtKB=Q9VUU8 Q9VUU8 Dmel\CG15715 PTHR21213:SF0 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 DROME|FlyBase=FBgn0031233|UniProtKB=Q9VPL5 Q9VPL5 Tbc1d15-17 PTHR22957:SF645 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 15 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0037671|UniProtKB=Q9VHG4 Q9VHG4 ATP6AP2 PTHR13351:SF1 RENIN RECEPTOR RENIN RECEPTOR positive regulation of signaling#GO:0023056;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of signal transduction#GO:0009967 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0020497|UniProtKB=Q9TVM2 Q9TVM2 emb PTHR11223:SF2 EXPORTIN 1/5 EXPORTIN-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0038100|UniProtKB=Q9VG13 Q9VG13 Paip2 PTHR13154:SF6 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 GEO05078P1 translation regulator activity#GO:0045182 negative regulation of translation#GO:0017148;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0050085|UniProtKB=Q9XZ34 Q9XZ34 Rif1 PTHR22928:SF4 TELOMERE-ASSOCIATED PROTEIN RIF1 TELOMERE-ASSOCIATED PROTEIN RIF1 cellular process#GO:0009987;organelle organization#GO:0006996;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0011723|UniProtKB=P55965 P55965 byn PTHR11267:SF106 T-BOX PROTEIN-RELATED T-RELATED PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cell fate specification#GO:0001708;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 DROME|FlyBase=FBgn0029137|UniProtKB=A0A4D6K4L3 A0A4D6K4L3 Patsas PTHR24161:SF17 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034160|UniProtKB=A0A0B4K7T3 A0A0B4K7T3 AAF57948 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0024556|UniProtKB=A1Z9E3 A1Z9E3 mEFTu1 PTHR43721:SF36 ELONGATION FACTOR TU-RELATED ELONGATION FACTOR TU, MITOCHONDRIAL translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 DROME|FlyBase=FBgn0036695|UniProtKB=Q9VVD9 Q9VVD9 Papst2 PTHR10778:SF8 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;purine nucleotide transmembrane transporter activity#GO:0015216;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0026575|UniProtKB=Q9VXG1 Q9VXG1 hang PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0036299|UniProtKB=Q9VTZ5 Q9VTZ5 Tsf2 PTHR11485:SF29 TRANSFERRIN TRANSFERRIN 2 metal ion transport#GO:0030001;iron ion transport#GO:0006826;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;extracellular region#GO:0005576;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;recycling endosome#GO:0055037 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0259735|UniProtKB=B7YZW3 B7YZW3 mtgo PTHR24099:SF11 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III DOMAIN CONTAINING 3BA ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0264561|UniProtKB=M9PIG4 M9PIG4 Glg1 PTHR11884:SF2 SELECTIN LIGAND RELATED GOLGI COMPLEX-LOCALIZED GLYCOPROTEIN 1, ISOFORM B membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 DROME|FlyBase=FBgn0023096|UniProtKB=Q0E8P6 Q0E8P6 btv PTHR10676:SF352 DYNEIN HEAVY CHAIN FAMILY PROTEIN CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544 plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;cell motility#GO:0048870;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0086134|UniProtKB=P40301 P40301 Prosalpha2 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0262601|UniProtKB=Q05856 Q05856 SmB PTHR10701:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type prespliceosome#GO:0071004;spliceosomal complex#GO:0005681;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0004893|UniProtKB=Q9VQU9 Q9VQU9 bowl PTHR14196:SF19 ODD-SKIPPED - RELATED PROTEIN BOWEL double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 tube morphogenesis#GO:0035239;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;tube development#GO:0035295;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;embryonic pattern specification#GO:0009880;negative regulation of macromolecule biosynthetic process#GO:0010558;embryo development#GO:0009790;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0043069|UniProtKB=Q9GU54 Q9GU54 MESK4 PTHR46282:SF1 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN DROME|FlyBase=FBgn0011754|UniProtKB=Q9I7D0 Q9I7D0 PhKgamma PTHR44167:SF18 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED PHOSPHORYLASE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 DROME|FlyBase=FBgn0035523|UniProtKB=Q9VZE7 Q9VZE7 Ctl1 PTHR12385:SF12 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0017482|UniProtKB=Q9W265 Q9W265 T3dh PTHR11496:SF83 ALCOHOL DEHYDROGENASE HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092 DROME|FlyBase=FBgn0250871|UniProtKB=Q9VYS2 Q9VYS2 pot PTHR46560:SF11 CYPHER, ISOFORM B GH09980P developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;anatomical structure development#GO:0048856 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 DROME|FlyBase=FBgn0035355|UniProtKB=Q9VZZ6 Q9VZZ6 BcDNA:RE30174 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;hydrolase activity#GO:0016787 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0261885|UniProtKB=Q8IN94 Q8IN94 osa PTHR12656:SF14 BRG-1 ASSOCIATED FACTOR 250 BAF250 TRITHORAX GROUP PROTEIN OSA binding#GO:0005488;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0035665|UniProtKB=Q9VRS7 Q9VRS7 Jon65Aiii PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0262562|UniProtKB=A0A0B4K6L3 A0A0B4K6L3 CG14318 PTHR12877:SF15 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0053758|UniProtKB=A1Z7U7 A1Z7U7 Dmel\CG33758 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0034417|UniProtKB=A1ZBG9 A1ZBG9 Dmel\CG15117 PTHR10066:SF70 BETA-GLUCURONIDASE BETA-GLUCURONIDASE carbohydrate binding#GO:0030246;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;binding#GO:0005488 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0031888|UniProtKB=Q9VM43 Q9VM43 Pvf2 PTHR21719:SF2 FI06402P-RELATED FI06402P-RELATED cellular process#GO:0009987;hemopoiesis#GO:0030097;cell development#GO:0048468;embryo development#GO:0009790;cell differentiation#GO:0030154;cell motility#GO:0048870;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;animal organ development#GO:0048513 DROME|FlyBase=FBgn0260398|UniProtKB=Q7JUY8 Q7JUY8 Pbp49 PTHR13421:SF16 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;core promoter sequence-specific DNA binding#GO:0001046;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 nucleic acid biosynthetic process#GO:0141187;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;snRNA transcription#GO:0009301;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0038260|UniProtKB=Q9VFG2 Q9VFG2 Dmel\CG14855 PTHR24064:SF467 SOLUTE CARRIER FAMILY 22 MEMBER FI01439P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0033781|UniProtKB=Q7JWR4 Q7JWR4 BcDNA:GH19585 PTHR33559:SF1 PROTEASOME ASSEMBLY CHAPERONE 4 PROTEASOME ASSEMBLY CHAPERONE 4 chaperone#PC00072 DROME|FlyBase=FBgn0004908|UniProtKB=Q06849 Q06849 Arl2 PTHR45697:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2 nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0010497|UniProtKB=Q9VKC9 Q9VKC9 dmGlut PTHR11662:SF415 SOLUTE CARRIER FAMILY 17 AT30085P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0030200|UniProtKB=Q9W2V3 Q9W2V3 RabX2 PTHR47980:SF101 LD44762P IP08727P-RELATED establishment of localization#GO:0051234;exocytosis#GO:0006887;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;localization within membrane#GO:0051668;endocytic recycling#GO:0032456;export from cell#GO:0140352 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136 DROME|FlyBase=FBgn0038401|UniProtKB=Q9VEY4 Q9VEY4 Dmel\CG5916 PTHR22957:SF686 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN GROWTH HORMONE-REGULATED TBC PROTEIN 1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0032032|UniProtKB=Q9VLM9 Q9VLM9 15010468 PTHR19288:SF46 4-NITROPHENYLPHOSPHATASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0015513|UniProtKB=A0A0B4K7Q6 A0A0B4K7Q6 mbc PTHR45653:SF13 DEDICATOR OF CYTOKINESIS MYOBLAST CITY, ISOFORM B enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;cell motility#GO:0048870;cell migration#GO:0016477;muscle structure development#GO:0061061;cell differentiation#GO:0030154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 Integrin signalling pathway#P00034>Dock180#P00930 DROME|FlyBase=FBgn0035445|UniProtKB=Q9VZP8 Q9VZP8 Ids PTHR45953:SF1 IDURONATE 2-SULFATASE IDURONATE 2-SULFATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 DROME|FlyBase=FBgn0014455|UniProtKB=Q27580 Q27580 Ahcy PTHR23420:SF0 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0036951|UniProtKB=Q9VW93 Q9VW93 Dmel\CG7017 PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0030566|UniProtKB=Q9VY34 Q9VY34 betaNACtes4 PTHR10351:SF23 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0266918|UniProtKB=Q9VZV5 Q9VZV5 CG32486 PTHR23059:SF4 CYSTEINE AND HISTIDINE-RICH PROTEIN 1 ZINC FINGER TRAF-TYPE-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0004055|UniProtKB=P10379 P10379 uzip PTHR31649:SF11 AGAP009604-PA PROTEIN UNZIPPED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0087007|UniProtKB=Q9VUE8 Q9VUE8 bbg PTHR11324:SF17 IL16-RELATED BIG BANG, ISOFORM C cytokine#PC00083;interleukin superfamily#PC00128 DROME|FlyBase=FBgn0262519|UniProtKB=O97159 O97159 Mi-2 PTHR45623:SF9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD3 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0021895|UniProtKB=Q9W1I6 Q9W1I6 ytr PTHR31077:SF1 U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0030039|UniProtKB=Q9W3F5 Q9W3F5 Dmel\CG12123 PTHR36693:SF1 GH02722P GH02722P DROME|FlyBase=FBgn0041105|UniProtKB=A0A0B4KH20 A0A0B4KH20 nerfin-2 PTHR15065:SF10 INSULINOMA-ASSOCIATED 1 NERVOUS FINGERS 2, ISOFORM B sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cell cycle process#GO:0010564;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038360|UniProtKB=Q9VF39 Q9VF39 Fam114A PTHR12842:SF6 FI01459P FI01459P DROME|FlyBase=FBgn0013548|UniProtKB=Q24371 Q24371 l(2)dtl PTHR22852:SF2 LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN DENTICLELESS PROTEIN HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;protein metabolic process#GO:0019538;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0243586|UniProtKB=Q9VBD0 Q9VBD0 Tb PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037039|UniProtKB=B7Z091 B7Z091 Dmel\CG10587 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0003270|UniProtKB=Q9Y0A7 Q9Y0A7 amos PTHR19290:SF162 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR AMOS-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0030263|UniProtKB=Q9VZ34 Q9VZ34 Dmel\CG2076 PTHR23291:SF112 BAX INHIBITOR-RELATED GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262 transport#GO:0006810;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;cellular component organization or biogenesis#GO:0071840;calcium ion transport#GO:0006816;mitochondrial calcium ion transmembrane transport#GO:0006851;organelle organization#GO:0006996;release of sequestered calcium ion into cytosol#GO:0051209;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;monoatomic ion transmembrane transport#GO:0034220;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular component organization#GO:0016043;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0031545|UniProtKB=Q9VQS0 Q9VQS0 bs30c03.y1 PTHR23162:SF10 OUTER DENSE FIBER OF SPERM TAILS 2 FI13205P regulation of cell projection assembly#GO:0060491;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0267378|UniProtKB=Q9VQ93 Q9VQ93 sau PTHR12704:SF2 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON DROME|FlyBase=FBgn0031451|UniProtKB=Q9VQF4 Q9VQF4 Pgk2 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;transferase activity#GO:0016740;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;transferase activity, transferring phosphorus-containing groups#GO:0016772;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphoglycerate kinase activity#GO:0004618 energy derivation by oxidation of organic compounds#GO:0015980;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 DROME|FlyBase=FBgn0001961|UniProtKB=O97182 O97182 Arpc1 PTHR10709:SF2 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT cellular component organization#GO:0016043;organelle organization#GO:0006996;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Huntington disease#P00029>Arp2/3 complex#P00811 DROME|FlyBase=FBgn0034789|UniProtKB=A0A6M3Q9L5 A0A6M3Q9L5 PIP5K59B PTHR23086:SF101 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE 59B, ISOFORM J-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;transferase#PC00220 DROME|FlyBase=FBgn0052269|UniProtKB=Q8SYS8 Q8SYS8 CG32270-RA PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0015797|UniProtKB=O18334 O18334 Rab6 PTHR24073:SF352 DRAB5-RELATED RAS-RELATED PROTEIN RAB6 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intra-Golgi vesicle-mediated transport#GO:0006891;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 small GTPase#PC00208;G-protein#PC00020 DROME|FlyBase=FBgn0028360|UniProtKB=Q9W3Y1 Q9W3Y1 Cdc7 PTHR44167:SF23 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0040628|UniProtKB=A0A0B4LHX0 A0A0B4LHX0 CAH16 PTHR18952:SF137 CARBONIC ANHYDRASE CARBONIC ANHYDRASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0011743|UniProtKB=P45891 P45891 Arp53D PTHR11937:SF607 ACTIN ACTIN-42A-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell division#GO:0051301;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cytoskeleton-dependent cytokinesis#GO:0061640;cortical actin cytoskeleton organization#GO:0030866 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Huntington disease#P00029>Actin#P00807 DROME|FlyBase=FBgn0029662|UniProtKB=Q9W4S1 Q9W4S1 CG12206 PTHR45669:SF18 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN CG12206-RELATED GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN CG12206-RELATED oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037665|UniProtKB=Q9VHH0 Q9VHH0 St2 PTHR11783:SF279 SULFOTRANSFERASE SULT MIP25022P1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0011692|UniProtKB=Q9VZF5 Q9VZF5 pav PTHR24115:SF600 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF23 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;nuclear division#GO:0000280;organelle assembly#GO:0070925;mitotic spindle organization#GO:0007052;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0035733|UniProtKB=Q9VS10 Q9VS10 Q9VS10 PTHR46149:SF3 MIP08469P MIP08469P binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 DROME|FlyBase=FBgn0023512|UniProtKB=Q9W541 Q9W541 eIF2Bepsilon PTHR45887:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON TRANSLATION INITIATION FACTOR EIF2B SUBUNIT EPSILON GTPase regulator activity#GO:0030695;translation initiation factor binding#GO:0031369;nucleoside-triphosphatase regulator activity#GO:0060589;translation initiation factor activity#GO:0003743;molecular function regulator activity#GO:0098772;translation factor activity#GO:0180051;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 DROME|FlyBase=FBgn0034988|UniProtKB=Q9W197 Q9W197 cN-IIIB PTHR13045:SF0 5'-NUCLEOTIDASE 7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 esterase#PC00097;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034001|UniProtKB=Q7JZM8 Q7JZM8 mRpL41 PTHR21338:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L41 LARGE RIBOSOMAL SUBUNIT PROTEIN ML41 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0034936|UniProtKB=Q9W1F7 Q9W1F7 Stoml2 PTHR43327:SF10 STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL transporter#PC00227 DROME|FlyBase=FBgn0035781|UniProtKB=Q961J8 Q961J8 Dmel\CG8560 PTHR11705:SF140 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI02848P-RELATED carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0032026|UniProtKB=Q9VLN6 Q9VLN6 Dme_CG7627 PTHR24223:SF448 ATP-BINDING CASSETTE SUB-FAMILY C FI20146P1-RELATED localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0004510|UniProtKB=Q04688 Q04688 Ets97D PTHR11849:SF195 ETS GA-BINDING PROTEIN ALPHA CHAIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 DROME|FlyBase=FBgn0002431|UniProtKB=P51592 P51592 hyd PTHR46276:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR5 E3 UBIQUITIN-PROTEIN LIGASE UBR5 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of signaling#GO:0023056;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Hedgehog signaling pathway#P00025>Ubiquitin ligase#P00693 DROME|FlyBase=FBgn0031037|UniProtKB=Q8IQW5 Q8IQW5 HspB8 PTHR45640:SF26 HEAT SHOCK PROTEIN HSP-12.2-RELATED RE23625P response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;protein folding#GO:0006457;protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 DROME|FlyBase=FBgn0051145|UniProtKB=A4VCL2 A4VCL2 CG31145 PTHR12450:SF26 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 EXTRACELLULAR SERINE_THREONINE PROTEIN CG31145 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0003964|UniProtKB=P20153 P20153 usp PTHR24083:SF193 NUCLEAR HORMONE RECEPTOR PROTEIN ULTRASPIRACLE sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular receptor signaling pathway#GO:0030522;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0032640|UniProtKB=Q9VJD4 Q9VJD4 Sgt PTHR45831:SF2 LD24721P LD24721P protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829;membrane#GO:0016020 DROME|FlyBase=FBgn0033935|UniProtKB=Q9V719 Q9V719 Sin1 PTHR13335:SF1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167 TORC2 signaling#GO:0038203;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;TOR signaling#GO:0031929;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;plasma membrane#GO:0005886;cytoplasm#GO:0005737;TOR complex#GO:0038201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033266|UniProtKB=Q7JVF1 Q7JVF1 Socs44A PTHR10155:SF32 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 6 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 kinase modulator#PC00140 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879;Interferon-gamma signaling pathway#P00035>SOCS#P00956 DROME|FlyBase=FBgn0030884|UniProtKB=Q9VX01 Q9VX01 Dmel\CG6847 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0260861|UniProtKB=Q9VLI9 Q9VLI9 Trs23 PTHR23249:SF15 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;TRAPP complex#GO:0030008;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0000464|UniProtKB=P16621 P16621 Lar PTHR19134:SF570 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE LAR catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 developmental process#GO:0032502;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DROME|FlyBase=FBgn0050404|UniProtKB=Q961C9 Q961C9 Tango11 PTHR16501:SF6 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 DROME|FlyBase=FBgn0032668|UniProtKB=Q9VJA0 Q9VJA0 Dmel\CG17681 PTHR20958:SF10 GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN GH05617P-RELATED DROME|FlyBase=FBgn0001404|UniProtKB=O01346 O01346 egh PTHR16779:SF1 BETA-1,4-MANNOSYLTRANSFERASE EGH GLYCOLIPID BETA-1,4-MANNOSYLTRANSFERASE EGH hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0042696|UniProtKB=Q86P06 Q86P06 NfI PTHR11492:SF8 NUCLEAR FACTOR I NUCLEAR FACTOR I, ISOFORM B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0265464|UniProtKB=Q9W3I9 Q9W3I9 Traf6 PTHR10131:SF152 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 6 signaling adaptor activity#GO:0035591;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;cell communication#GO:0007154;immune response#GO:0006955;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;cellular response to molecule of bacterial origin#GO:0071219;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;defense response to other organism#GO:0098542;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496 synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;cell junction#GO:0030054;cytoplasmic side of membrane#GO:0098562 scaffold/adaptor protein#PC00226 p38 MAPK pathway#P05918>TRAF6#P06038;p53 pathway#P00059>TRAF#P04620;Apoptosis signaling pathway#P00006>TRAF2#P00306;Toll receptor signaling pathway#P00054>TRAF6#P01371 DROME|FlyBase=FBgn0053349|UniProtKB=A1Z6S4 A1Z6S4 ppk25 PTHR11690:SF240 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 25-RELATED transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0001083|UniProtKB=Q9VYR4 Q9VYR4 fw PTHR19325:SF537 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING FURROWED, ISOFORM A defense/immunity protein#PC00090;complement component#PC00078 DROME|FlyBase=FBgn0038834|UniProtKB=Q9VDH8 Q9VDH8 RpS30 PTHR12650:SF15 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI RIBOSOMAL PROTEIN S30, ISOFORM A cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 DROME|FlyBase=FBgn0004838|UniProtKB=P48809 P48809 Hrb27C PTHR48027:SF23 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED DAZ-ASSOCIATED PROTEIN 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730 positive regulation of biosynthetic process#GO:0009891;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;sexual reproduction#GO:0019953;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;positive regulation of RNA metabolic process#GO:0051254;developmental process involved in reproduction#GO:0003006;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;gamete generation#GO:0007276;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038191|UniProtKB=Q9VFP5 Q9VFP5 Kots PTHR22948:SF84 TUDOR DOMAIN CONTAINING PROTEIN FI02030P-RELATED sexual reproduction#GO:0019953;pattern specification process#GO:0007389;piRNA processing#GO:0034587;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;cell maturation#GO:0048469;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;regionalization#GO:0003002;developmental maturation#GO:0021700;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;cell differentiation#GO:0030154;anterior/posterior pattern specification#GO:0009952;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;anterior/posterior axis specification#GO:0009948;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;oogenesis#GO:0048477;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037715|UniProtKB=Q9VHB1 Q9VHB1 Mpc2a PTHR14154:SF154 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;intracellular transport#GO:0046907;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monocarboxylic acid transport#GO:0015718 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0035280|UniProtKB=Q9W078 Q9W078 Cpr62Bb PTHR12236:SF103 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 62BB, ISOFORM A extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036846|UniProtKB=M9PI97 M9PI97 MESR6 PTHR13225:SF3 MISEXPRESSION SUPPRESSOR OF RAS 6 UPF0489 PROTEIN C5ORF22 DROME|FlyBase=FBgn0002773|UniProtKB=P18432 P18432 Mlc2 PTHR23049:SF71 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0003046|UniProtKB=P14484 P14484 Pcp PTHR10380:SF238 CUTICLE PROTEIN CUTICULAR PROTEIN 65EA-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0033031|UniProtKB=A1Z6G9 A1Z6G9 Dmel\CG8245 PTHR12265:SF30 TRANSMEMBRANE PROTEIN 53 TRANSMEMBRANE PROTEIN 53 DROME|FlyBase=FBgn0035624|UniProtKB=Q9VRN3 Q9VRN3 Eaf6 PTHR13476:SF0 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0030108|UniProtKB=Q9W367 Q9W367 Gr8a PTHR21143:SF104 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 8A-RELATED dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;cell body#GO:0044297;neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039751|UniProtKB=Q9VA97 Q9VA97 Dmel\CG1983 PTHR10146:SF18 PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 cellular process#GO:0009987;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0043532|UniProtKB=Q4V3N1 Q4V3N1 Obp56i PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0021875|UniProtKB=Q9W1A3 Q9W1A3 Zfrp8 PTHR12298:SF8 PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED US5 ASSEMBLY CHAPERONE PDCD2 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031918|UniProtKB=Q9VM07 Q9VM07 Dmel\CG6055 PTHR21407:SF1 RE43931P-RELATED RE43931P DROME|FlyBase=FBgn0033494|UniProtKB=A1Z856 A1Z856 KCNQ PTHR11537:SF259 VOLTAGE-GATED POTASSIUM CHANNEL KCNQ POTASSIUM CHANNEL, ISOFORM F voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;potassium ion transport#GO:0006813;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ion channel#PC00133;voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0050491|UniProtKB=Q7JUS1 Q7JUS1 CG30491_CG30495 PTHR24320:SF289 RETINOL DEHYDROGENASE GH10714P-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0283652|UniProtKB=Q9VPM0 Q9VPM0 Rpp30 PTHR13031:SF0 RIBONUCLEASE P SUBUNIT P30 RIBONUCLEASE P PROTEIN SUBUNIT P30 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;endonuclease complex#GO:1905348;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;multimeric ribonuclease P complex#GO:0030681;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolar ribonuclease P complex#GO:0005655;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;endoribonuclease#PC00094 DROME|FlyBase=FBgn0039958|UniProtKB=Q7PLS1 Q7PLS1 Dmel\CG12567 PTHR13622:SF16 THIAMIN PYROPHOSPHOKINASE SI:DKEY-6N6.2 hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 kinase#PC00137;transferase#PC00220 DROME|FlyBase=FBgn0003292|UniProtKB=Q9VTK2 Q9VTK2 rt PTHR10050:SF51 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0041171|UniProtKB=Q9VZF4 Q9VZF4 ago PTHR22847:SF745 WD40 REPEAT PROTEIN F-BOX_WD REPEAT-CONTAINING PROTEIN 7 regulation of mitotic nuclear division#GO:0007088;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of mitotic cell cycle#GO:0007346 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Notch signaling pathway#P00045>Sel 10#P01102 DROME|FlyBase=FBgn0034687|UniProtKB=Q9W2A0 Q9W2A0 Dmel\CG11475 PTHR12260:SF6 DAMAGE-CONTROL PHOSPHATASE ARMT1 DAMAGE-CONTROL PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stress#GO:0006950;response to stimulus#GO:0050896 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0053217|UniProtKB=Q8MS38 Q8MS38 Dmel\CG33217 PTHR34105:SF1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030630|UniProtKB=Q9VXW3 Q9VXW3 Dmel\CG12608 PTHR44675:SF1 PAK1 INTERACTING PROTEIN 1 P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1 enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;kinase inhibitor activity#GO:0019210;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 DROME|FlyBase=FBgn0041781|UniProtKB=F2FB81 F2FB81 SCAR PTHR12902:SF39 WASP-1 WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER protein-containing complex binding#GO:0044877;protein binding#GO:0005515;protein kinase A regulatory subunit binding#GO:0034237;protein kinase A binding#GO:0051018;binding#GO:0005488 cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0034748|UniProtKB=Q9W232 Q9W232 Alkbh8 PTHR13069:SF21 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA (CARBOXYMETHYLURIDINE(34)-5-O)-METHYLTRANSFERASE ALKBH8 binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DROME|FlyBase=FBgn0039737|UniProtKB=Q9VAC1 Q9VAC1 anon-WO0153538.36 PTHR21432:SF21 ACETYL-COA HYDROLASE-RELATED GM14349P membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 hydrolase#PC00121 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 DROME|FlyBase=FBgn0038089|UniProtKB=Q9VG22 Q9VG22 d-cup PTHR23055:SF190 CALCIUM BINDING PROTEINS AT17667P-RELATED small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 DROME|FlyBase=FBgn0034272|UniProtKB=A1ZAY9 A1ZAY9 Ir54a PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0003279|UniProtKB=P09180 P09180 RpL4 PTHR19431:SF0 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 RNA binding#GO:0003723;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0038404|UniProtKB=Q9VEY1 Q9VEY1 Dmel\CG8925 PTHR24064:SF187 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0050042|UniProtKB=A1Z8Y3 A1Z8Y3 Cpr49Ab PTHR10380:SF200 CUTICLE PROTEIN CUTICULAR PROTEIN 49AB-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0032033|UniProtKB=Q9VLM7 Q9VLM7 Tmem126 PTHR16296:SF2 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 TRANSMEMBRANE PROTEIN 126A cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0051682|UniProtKB=Q8IPY9 Q8IPY9 Tengl1 PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520 catabolic process#GO:0009056;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;cellular component organization#GO:0016043;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Apoptosis signaling pathway#P00006>endoG#P00279 DROME|FlyBase=FBgn0259794|UniProtKB=Q8T3Y0 Q8T3Y0 sinah PTHR45877:SF2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SINA-RELATED ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433 DROME|FlyBase=FBgn0038458|UniProtKB=Q9VEQ6 Q9VEQ6 VhaM9.7-d PTHR12263:SF0 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0051922|UniProtKB=Q8IPW7 Q8IPW7 Snrnp20 PTHR16465:SF0 NUCLEASE-RELATED ZINC FINGER MATRIN-TYPE PROTEIN 5 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038110|UniProtKB=Q9VG04 Q9VG04 dMEMO PTHR11060:SF0 PROTEIN MEMO1 PROTEIN MEMO1 DROME|FlyBase=FBgn0031951|UniProtKB=Q9VLW8 Q9VLW8 r2d2 PTHR46205:SF4 LOQUACIOUS, ISOFORM B LD06392P double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 DROME|FlyBase=FBgn0030433|UniProtKB=Q9VYI3 Q9VYI3 mRpL49 PTHR13477:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49 LARGE RIBOSOMAL SUBUNIT PROTEIN ML49 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 DROME|FlyBase=FBgn0053543|UniProtKB=Q59E14 Q59E14 elff PTHR12231:SF259 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN FACTOR OF INTERPULSE INTERVAL-RELATED cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;synapse organization#GO:0050808 leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell junction#GO:0030054;cell projection membrane#GO:0031253;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0004856|UniProtKB=P39736 P39736 Bx42 PTHR12096:SF0 NUCLEAR PROTEIN SKIP-RELATED SNW DOMAIN-CONTAINING PROTEIN 1 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0032358|UniProtKB=Q9VKH6 Q9VKH6 Ppt2 PTHR11247:SF27 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 LYSOSOMAL THIOESTERASE PPT2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0040318|UniProtKB=A0A6J3T5M5 A0A6J3T5M5 HGTX PTHR24340:SF35 HOMEOBOX PROTEIN NKX HGTX, ISOFORM C RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0033983|UniProtKB=Q9V778 Q9V778 Agps PTHR46568:SF1 ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 DROME|FlyBase=FBgn0035612|UniProtKB=B7Z0B9 B7Z0B9 frm PTHR24024:SF19 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A FARMER, ISOFORM H surfactant#PC00212;structural protein#PC00211 DROME|FlyBase=FBgn0038076|UniProtKB=Q9VG40 Q9VG40 Cyp313a4 PTHR24305:SF224 CYTOCHROME P450 CYTOCHROME P450 313A1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0051040|UniProtKB=Q9VAD6 Q9VAD6 Cog7 PTHR21443:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7 endomembrane system organization#GO:0010256;protein localization to organelle#GO:0033365;Golgi organization#GO:0007030;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;protein localization to Golgi apparatus#GO:0034067 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119 DROME|FlyBase=FBgn0050323|UniProtKB=A1ZB07 A1ZB07 Dmel\CG30323 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0036345|UniProtKB=Q9VU49 Q9VU49 Dmel\CG17300 PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT B, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252 ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144 cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0052707|UniProtKB=Q9W395 Q9W395 APC4 PTHR13260:SF0 ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4 ANAPHASE-PROMOTING COMPLEX SUBUNIT 4 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152 DROME|FlyBase=FBgn0039474|UniProtKB=Q9VB90 Q9VB90 Dmel\CG6283 PTHR11610:SF178 LIPASE FI01825P-RELATED hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0019960|UniProtKB=P91928 P91928 Mitofilin PTHR15415:SF7 MITOFILIN MICOS COMPLEX SUBUNIT MIC60 DROME|FlyBase=FBgn0038057|UniProtKB=Q9VG60 Q9VG60 Polr3C PTHR12949:SF0 RNA POLYMERASE III DNA DIRECTED -RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0036415|UniProtKB=Q7K2I4 Q7K2I4 Dmel\CG7768 PTHR11071:SF582 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|FlyBase=FBgn0003513|UniProtKB=E1JIM6 E1JIM6 ss PTHR10649:SF12 ARYL HYDROCARBON RECEPTOR SPINELESS, ISOFORM C transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0043458|UniProtKB=Q9W0E8 Q9W0E8 CG12084 PTHR12904:SF23 FAMILY NOT NAMED PROTEIN ZER-1 HOMOLOG transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0041100|UniProtKB=Q7KTX7 Q7KTX7 park PTHR11685:SF464 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE PARKIN ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 autophagy of mitochondrion#GO:0000422;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;autophagy#GO:0006914;regulation of trans-synaptic signaling#GO:0099177;macroautophagy#GO:0016236;biological regulation#GO:0065007;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0038327|UniProtKB=Q9VF77 Q9VF77 Trax PTHR10741:SF5 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN-ASSOCIATED PROTEIN X nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0039131|UniProtKB=Q9VCF6 Q9VCF6 Dmel\CG12268 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0032198|UniProtKB=Q9VL18 Q9VL18 eEF1delta PTHR11595:SF21 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 DROME|FlyBase=FBgn0031500|UniProtKB=Q8IPZ3 Q8IPZ3 Rtn4ip1 PTHR11695:SF649 ALCOHOL DEHYDROGENASE RELATED NAD(P)H OXIDOREDUCTASE RTN4IP1, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0259935|UniProtKB=Q7KU81 Q7KU81 CG18656 PTHR13968:SF35 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RRM DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034310|UniProtKB=A1YK02 A1YK02 Nup75 PTHR13373:SF21 FROUNT PROTEIN-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP85 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 protein transport#GO:0015031;protein import into nucleus#GO:0006606;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 structural protein#PC00211 DROME|FlyBase=FBgn0043796|UniProtKB=Q9W409 Q9W409 Dmel\CG12219 PTHR24403:SF116 ZINC FINGER PROTEIN ENHANCER OF VARIEGATION 3-9-RELATED DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0038498|UniProtKB=Q9BMG9 Q9BMG9 beat-IIa PTHR21261:SF6 BEAT PROTEIN BEATEN PATH IIA-RELATED intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0036754|UniProtKB=Q9VVK8 Q9VVK8 ais PTHR24031:SF594 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX52-RELATED cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0050496|UniProtKB=Q7JRC9 Q7JRC9 CG30493_CG30496_l(2)08492 PTHR15430:SF1 GLOMULIN RE73310P enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 regulation of catabolic process#GO:0009894;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of proteasomal protein catabolic process#GO:0061136;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0265002|UniProtKB=Q9VL42 Q9VL42 CG34048 PTHR45813:SF8 IG-LIKE DOMAIN-CONTAINING PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0029834|UniProtKB=Q9W444 Q9W444 Dmel\CG5937 PTHR10663:SF344 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 3 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0003134|UniProtKB=P48461 P48461 Pp1alpha-96A PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE-RELATED phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 DROME|FlyBase=FBgn0037955|UniProtKB=Q8SXC2 Q8SXC2 Kyat PTHR43807:SF23 FI04487P FI04487P transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 DROME|FlyBase=FBgn0064119|UniProtKB=E1JIQ7 E1JIQ7 CG32921-ORFB PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED dicarboxylic acid transmembrane transporter activity#GO:0005310;succinate transmembrane transporter activity#GO:0015141;C4-dicarboxylate transmembrane transporter activity#GO:0015556;citrate transmembrane transporter activity#GO:0015137;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 succinate transport#GO:0015744;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;citrate transport#GO:0015746;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;tricarboxylic acid transport#GO:0006842 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0036242|UniProtKB=Q9VTS7 Q9VTS7 Dmel\CG6793 PTHR39944:SF1 FAMILY NOT NAMED CALDESMON-RELATED PROTEIN-RELATED DROME|FlyBase=FBgn0029580|UniProtKB=Q9W587 Q9W587 Dmel\CG14778 PTHR11266:SF75 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 IP10007P-RELATED intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 transporter#PC00227 DROME|FlyBase=FBgn0002899|UniProtKB=Q9VSE2 Q9VSE2 mus301 PTHR47961:SF12 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED HELICASE POLQ-LIKE ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0036328|UniProtKB=Q9VU29 Q9VU29 Mdh2b PTHR11540:SF76 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 DROME|FlyBase=FBgn0002781|UniProtKB=Q86B87 Q86B87 mod(mdg4) PTHR23110:SF92 BTB DOMAIN TRANSCRIPTION FACTOR MODIFIER OF MDG4 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0030243|UniProtKB=A0A6H2EEJ8 A0A6H2EEJ8 Dmel\CG2186 PTHR22014:SF2 RNA-BINDING PROTEIN 33 RNA-BINDING PROTEIN 33 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 DROME|FlyBase=FBgn0266377|UniProtKB=Q6NNF2 Q6NNF2 Pde8 PTHR11347:SF206 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532 phosphodiesterase#PC00185;hydrolase#PC00121 DROME|FlyBase=FBgn0035592|UniProtKB=Q9VRJ8 Q9VRJ8 CG10674 PTHR13193:SF0 CGI-140 PAT COMPLEX SUBUNIT ASTERIX cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0034179|UniProtKB=Q7K161 Q7K161 IPP PTHR11200:SF310 INOSITOL 5-PHOSPHATASE LD06095P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;ruffle#GO:0001726;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0002563|UniProtKB=P11996 P11996 Lsp1beta PTHR11511:SF5 LARVAL STORAGE PROTEIN/PHENOLOXIDASE FAT-BODY PROTEIN 1-RELATED DROME|FlyBase=FBgn0033836|UniProtKB=Q5BIL9 Q5BIL9 Gns PTHR43108:SF8 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER SD21168P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;glycoprotein metabolic process#GO:0009100 hydrolase#PC00121 DROME|FlyBase=FBgn0038629|UniProtKB=Q9VE59 Q9VE59 Dmel\CG14304 PTHR22933:SF18 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0001341|UniProtKB=Q9W5E4 Q9W5E4 Mybbp1A PTHR13213:SF3 MYB-BINDING PROTEIN 1A FAMILY MEMBER MYB-BINDING PROTEIN 1A sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0035001|UniProtKB=Q9W179 Q9W179 Slik PTHR48012:SF2 STERILE20-LIKE KINASE, ISOFORM B-RELATED STERILE20-LIKE KINASE, ISOFORM B protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0033133|UniProtKB=A1Z6U3 A1Z6U3 Tsp42Ek PTHR19282:SF521 TETRASPANIN AT12771P-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0004655|UniProtKB=Q9W517 Q9W517 wapl PTHR22100:SF13 WINGS APART-LIKE PROTEIN HOMOLOG WINGS APART-LIKE PROTEIN HOMOLOG DROME|FlyBase=FBgn0030478|UniProtKB=Q9VYD9 Q9VYD9 Alat PTHR11751:SF29 ALANINE AMINOTRANSFERASE ALANINE TRANSAMINASE transaminase#PC00216;transferase#PC00220 DROME|FlyBase=FBgn0032292|UniProtKB=Q9VKR0 Q9VKR0 EMC3 PTHR13116:SF5 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;protein localization to organelle#GO:0033365 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 DROME|FlyBase=FBgn0289994|UniProtKB=P02518 P02518 Hsp27 PTHR45640:SF40 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN 22-RELATED protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 DROME|FlyBase=FBgn0030018|UniProtKB=Q95UN8 Q95UN8 slpr PTHR44329:SF293 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Huntington disease#P00029>MLK-2#P00764 DROME|FlyBase=FBgn0035153|UniProtKB=Q9W0N9 Q9W0N9 ebd1 PTHR16021:SF13 MANSC DOMAIN CONTAINING PROTEIN 1 EARTHBOUND 1-RELATED DROME|FlyBase=FBgn0037892|UniProtKB=Q9VGP7 Q9VGP7 mRpL40 PTHR13359:SF2 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML40 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0031093|UniProtKB=Q9W5W7 Q9W5W7 Dmel\CG9581 PTHR43226:SF4 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO AMINOPEPTIDASE 3 catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153 DROME|FlyBase=FBgn0039780|UniProtKB=Q9VA64 Q9VA64 PH4alphaNE1 PTHR10869:SF216 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROCOLLAGEN-PROLINE 4-DIOXYGENASE oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 oxidoreductase complex#GO:1990204;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0052564|UniProtKB=Q8IR01 Q8IR01 Dmel\CG32564 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0052396|UniProtKB=Q9VRX3 Q9VRX3 betaTub65B PTHR11588:SF504 TUBULIN TUBULIN BETA-1 CHAIN-RELATED carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 cytoskeletal protein#PC00085;tubulin#PC00228 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 DROME|FlyBase=FBgn0003515|UniProtKB=P45843 P45843 st PTHR48041:SF150 ABC TRANSPORTER G FAMILY MEMBER 28 PROTEIN SCARLET active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle membrane#GO:0031090 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0039744|UniProtKB=Q9VAA7 Q9VAA7 Rpp14b PTHR15441:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P14 RIBONUCLEASE P PROTEIN SUBUNIT P14 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;endonuclease complex#GO:1905348;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 endoribonuclease#PC00094 DROME|FlyBase=FBgn0052203|UniProtKB=Q3HKQ3 Q3HKQ3 Spn75F PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0038871|UniProtKB=Q9VDC8 Q9VDC8 mat1 PTHR13610:SF9 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ATP SYNTHASE SUBUNIT C LYSINE N-METHYLTRANSFERASE protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0264298|UniProtKB=A0A0B4KFH2 A0A0B4KFH2 Dmel\CG43776 PTHR10334:SF613 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0037251|UniProtKB=Q9VN27 Q9VN27 Lipt2 PTHR10993:SF7 OCTANOYLTRANSFERASE OCTANOYL-[ACYL-CARRIER-PROTEIN]:PROTEIN N-OCTANOYLTRANSFERASE LIPT2, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 DROME|FlyBase=FBgn0014037|UniProtKB=Q9VW51 Q9VW51 Ell PTHR23288:SF17 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of biological process#GO:0050789;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of transcription by RNA polymerase II#GO:0006357;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;transcription by RNA polymerase II#GO:0006366;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 general transcription factor#PC00259 DROME|FlyBase=FBgn0033155|UniProtKB=Q7JVP4 Q7JVP4 Br140 PTHR13793:SF169 PHD FINGER PROTEINS BROMODOMAIN-CONTAINING PROTEIN HOMOLOG chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0266719|UniProtKB=Q9VBY8 Q9VBY8 stac PTHR45999:SF2 UNC-13-4A, ISOFORM B PROTEIN UNC-13 HOMOLOG 4B secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0036180|UniProtKB=Q9VTK7 Q9VTK7 Duba PTHR12419:SF122 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 5 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 positive regulation of TORC1 signaling#GO:1904263;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;positive regulation of signaling#GO:0023056;negative regulation of cell communication#GO:0010648;positive regulation of TOR signaling#GO:0032008 cysteine protease#PC00081 DROME|FlyBase=FBgn0037360|UniProtKB=Q9VNG1 Q9VNG1 CG2182 PTHR13601:SF2 GAMETOGENETIN-BINDING PROTEIN 2 GAMETOGENETIN-BINDING PROTEIN 2-LIKE negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031287|UniProtKB=Q9VPU4 Q9VPU4 Dmel\CG4291 PTHR13173:SF10 WW DOMAIN BINDING PROTEIN 4 WW DOMAIN-BINDING PROTEIN 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011 DROME|FlyBase=FBgn0031253|UniProtKB=Q9VPP7 Q9VPP7 BcDNA:AT13539 PTHR31051:SF1 PROTEASOME ASSEMBLY CHAPERONE 3 PROTEASOME ASSEMBLY CHAPERONE 3 chaperone#PC00072 DROME|FlyBase=FBgn0039839|UniProtKB=Q9V9Y5 Q9V9Y5 ppk24 PTHR11690:SF253 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 18-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0037668|UniProtKB=Q9VHG7 Q9VHG7 Dmel\CG16736 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310 carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;phosphate ion transport#GO:0006817;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0033431|UniProtKB=Q8MR45 Q8MR45 CG1827 PTHR10188:SF50 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764 protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0038828|UniProtKB=Q9VDI6 Q9VDI6 anon-Liu PTHR15451:SF19 ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039562|UniProtKB=Q9VAY2 Q9VAY2 Gp93 PTHR11528:SF144 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056 perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 Hsp90 family chaperone#PC00028;chaperone#PC00072 DROME|FlyBase=FBgn0288469|UniProtKB=Q9VWB0 Q9VWB0 Pex23 PTHR23250:SF1 DYSFERLIN-RELATED TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN DROME|FlyBase=FBgn0261698|UniProtKB=A8DY93 A8DY93 SLO2 PTHR10027:SF41 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN SLOWPOKE 2, ISOFORM D gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0038577|UniProtKB=Q9VEC2 Q9VEC2 Dmel\CG12321 PTHR12970:SF1 PROTEASOME ASSEMBLY CHAPERONE 2 PROTEASOME ASSEMBLY CHAPERONE 2 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 DROME|FlyBase=FBgn0266721|UniProtKB=Q9VH25 Q9VH25 gammaSnap2 PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 DROME|FlyBase=FBgn0266000|UniProtKB=A8JUX7 A8JUX7 Dmel\CG44774 PTHR13422:SF12 SIN3-HDAC COMPLEX-ASSOCIATED FACTOR SIN3-HDAC COMPLEX-ASSOCIATED FACTOR negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;regulation of locomotion#GO:0040012 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634 DROME|FlyBase=FBgn0014179|UniProtKB=Q27403 Q27403 gcm PTHR12414:SF8 GLIAL CELLS MISSING RELATED/GLIDE TRANSCRIPTION FACTOR GLIAL CELLS MISSING-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;gliogenesis#GO:0042063;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0260464|UniProtKB=Q9VFR1 Q9VFR1 abitram PTHR13651:SF1 PROTEIN ABITRAM PROTEIN ABITRAM actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin monomer binding#GO:0003785;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 anatomical structure development#GO:0048856;regulation of cell projection assembly#GO:0060491;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;dendrite morphogenesis#GO:0048813;regulation of supramolecular fiber organization#GO:1902903;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;regulation of filopodium assembly#GO:0051489;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;dendrite development#GO:0016358;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cell differentiation#GO:0030154;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;regulation of anatomical structure size#GO:0090066;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of actin cytoskeleton organization#GO:0032956;neuron projection development#GO:0031175;cellular process#GO:0009987 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell leading edge#GO:0031252;nucleus#GO:0005634;neuron projection#GO:0043005;lamellipodium#GO:0030027;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;filopodium#GO:0030175;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995 DROME|FlyBase=FBgn0027348|UniProtKB=Q9V3S9 Q9V3S9 bgm PTHR24096:SF391 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE HEIMDALL-RELATED ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 DROME|FlyBase=FBgn0032949|UniProtKB=Q9V9S0 Q9V9S0 Lamp1 PTHR11506:SF35 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5 establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0050398|UniProtKB=Q8MLV2 Q8MLV2 Dmel\CG30398 PTHR21222:SF2 MIT DOMAIN-CONTAINING PROTEIN 1 FI11682P-RELATED DROME|FlyBase=FBgn0033389|UniProtKB=A1Z7R8 A1Z7R8 Rad51D PTHR46457:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;four-way junction DNA binding#GO:0000400;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;response to stimulus#GO:0050896;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;telomere organization#GO:0032200;organelle fission#GO:0048285;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;homologous recombination#GO:0035825;reproductive process#GO:0022414;DNA damage response#GO:0006974;DNA repair#GO:0006281;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;nucleobase-containing compound metabolic process#GO:0006139 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0038767|UniProtKB=Q9VDQ4 Q9VDQ4 trem PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0051199|UniProtKB=Q9I7I3 Q9I7I3 CG17837 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0020930|UniProtKB=Q7K579 Q7K579 Dgkepsilon PTHR11255:SF54 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE EPSILON lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 primary metabolic process#GO:0044238;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;kinase#PC00137 DROME|FlyBase=FBgn0011725|UniProtKB=Q8IMX1 Q8IMX1 twin PTHR12121:SF100 CARBON CATABOLITE REPRESSOR PROTEIN 4 POLY(A)-SPECIFIC RIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;CCR4-NOT complex#GO:0030014;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0035669|UniProtKB=Q9VRT1 Q9VRT1 Dmel\CG6592 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0038953|UniProtKB=Q9VD22 Q9VD22 Dmel\CG18596 PTHR12029:SF11 RNA METHYLTRANSFERASE TRNA (GUANOSINE(18)-2'-O)-METHYLTRANSFERASE TARBP1 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0013765|UniProtKB=P54623 P54623 cnn PTHR46501:SF10 MYOMEGALIN CENTROSOMIN regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cell cycle#GO:0007049;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;centrosome#GO:0005813;cytoskeleton#GO:0005856 DROME|FlyBase=FBgn0262594|UniProtKB=A1Z7Y9 A1Z7Y9 CheA46a PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0036580|UniProtKB=Q9VUZ8 Q9VUZ8 PDCD-5 PTHR10840:SF0 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0262125|UniProtKB=A0A0B4K5Z8 A0A0B4K5Z8 Sec23 PTHR11141:SF0 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475 vesicle coat protein#PC00235;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0261674|UniProtKB=Q9VU13 Q9VU13 EP(3)3622 PTHR46473:SF29 GH08155P LD45603P DROME|FlyBase=FBgn0026149|UniProtKB=O76857 O76857 BCL7-like PTHR12767:SF9 BCL7 RELATED BCL7-LIKE cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 DROME|FlyBase=FBgn0003943|UniProtKB=P0CG69 P0CG69 Ubi-p63E PTHR10666:SF512 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN EL40 FUSION PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;nucleus#GO:0005634;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0024994|UniProtKB=O76865 O76865 Ugalt PTHR10231:SF106 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSLOCATOR carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;nucleobase-containing compound transmembrane transporter activity#GO:0015932;UDP-galactose transmembrane transporter activity#GO:0005459;organophosphate ester transmembrane transporter activity#GO:0015605;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleotide-sugar transmembrane transport#GO:0015780;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 transporter#PC00227 DROME|FlyBase=FBgn0261789|UniProtKB=Q9VI10 Q9VI10 SmD2 PTHR12777:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 DROME|FlyBase=FBgn0260995|UniProtKB=A0A0C4DHN4 A0A0C4DHN4 dpr21 PTHR23279:SF13 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 21 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256 DROME|FlyBase=FBgn0002283|UniProtKB=Q9VV77 Q9VV77 l(3)73Ah PTHR45893:SF3 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 3 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;PcG protein complex#GO:0031519 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0050156|UniProtKB=Q5U0V4 Q5U0V4 Dmel\CG30156 PTHR43908:SF3 AT29763P-RELATED AT29763P-RELATED Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular response to misfolded protein#GO:0071218;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 DROME|FlyBase=FBgn0032644|UniProtKB=Q9VJD0 Q9VJD0 Dmel\CG5131 PTHR21711:SF0 MITOCHONDRIAL INNER MEMBRANE PROTEASE MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;mitochondrion organization#GO:0007005;biosynthetic process#GO:0009058;mitochondrial respiratory chain complex assembly#GO:0033108;metabolic process#GO:0008152;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;proteolysis#GO:0006508;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0266708|UniProtKB=Q7JVA5 Q7JVA5 Cep89 PTHR36170:SF1 CENTROSOMAL PROTEIN OF 89 KDA CENTROSOMAL PROTEIN OF 89 KDA plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 ciliary transition fiber#GO:0097539;microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0266098|UniProtKB=Q9W4E2 Q9W4E2 rg PTHR13743:SF162 BEIGE/BEACH-RELATED NEUROBEACHIN protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0000119|UniProtKB=A1Z9D7 A1Z9D7 arr PTHR46513:SF41 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431 DROME|FlyBase=FBgn0037998|UniProtKB=Q9VGC3 Q9VGC3 Cog1 PTHR31658:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0039928|UniProtKB=Q9V498 Q9V498 Cals PTHR14139:SF2 CALSYNTENIN CALSYNTENIN-1 binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 positive regulation of developmental process#GO:0051094;positive regulation of synapse assembly#GO:0051965;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of synapse assembly#GO:0051963;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 cell junction#GO:0030054;synaptic membrane#GO:0097060;cell surface#GO:0009986;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0035626|UniProtKB=Q9VRN5 Q9VRN5 lin-28 PTHR46109:SF1 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0086610|UniProtKB=Q7KS21 Q7KS21 Dmel\CG33342 PTHR21398:SF11 AGAP007094-PA HDC15381-RELATED DROME|FlyBase=FBgn0036397|UniProtKB=Q9VUB4 Q9VUB4 Nprl3 PTHR13153:SF5 CGTHBA PROTEIN -14 GENE PROTEIN GATOR1 COMPLEX PROTEIN NPRL3 regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;negative regulation of TORC1 signaling#GO:1904262;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896 protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859 DROME|FlyBase=FBgn0034808|UniProtKB=Q9W1W4 Q9W1W4 Dmel\CG9896 PTHR33964:SF1 RE45066P-RELATED RE45066P DROME|FlyBase=FBgn0002973|UniProtKB=P16554 P16554 numb PTHR11232:SF45 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER GENE 7694-RELATED signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971 regulation of cell differentiation#GO:0045595;regulation of nervous system development#GO:0051960;regulation of neurogenesis#GO:0050767;regulation of multicellular organismal development#GO:2000026;regulation of cell development#GO:0060284;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>Numb#P01118 DROME|FlyBase=FBgn0028398|UniProtKB=Q9U5W9 Q9U5W9 Taf10 PTHR21242:SF0 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 catalytic complex#GO:1902494;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;peptidase complex#GO:1905368;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0031771|UniProtKB=Q9VMI3 Q9VMI3 ND-51 PTHR11780:SF10 NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1 NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176 DROME|FlyBase=FBgn0017448|UniProtKB=P91659 P91659 Dmel\CG2187 PTHR42985:SF46 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER FI02923P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;sodium ion transport#GO:0006814 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0000183|UniProtKB=P16568 P16568 BicD PTHR31233:SF6 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;microtubule anchoring#GO:0034453;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0036160|UniProtKB=Q9VTI3 Q9VTI3 Khkl2 PTHR43085:SF55 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 carbohydrate metabolic process#GO:0005975;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of macromolecule metabolic process#GO:0060255;small molecule metabolic process#GO:0044281;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of glycogen biosynthetic process#GO:0005979;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;regulation of carbohydrate metabolic process#GO:0006109;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 DROME|FlyBase=FBgn0033244|UniProtKB=A1Z782 A1Z782 Dmel\CG8726 PTHR22999:SF40 PX SERINE/THREONINE KINASE PXK PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0036448|UniProtKB=Q9VUH6 Q9VUH6 mop PTHR23030:SF45 PCD6 INTERACTING PROTEIN-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 protein localization to organelle#GO:0033365;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;localization#GO:0051179;protein localization to vacuole#GO:0072665;localization within membrane#GO:0051668;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;macromolecule localization#GO:0033036;early endosome to late endosome transport#GO:0045022;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;endocytic recycling#GO:0032456;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;protein transport#GO:0015031;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;endosomal transport#GO:0016197;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0053265|UniProtKB=Q7KUI0 Q7KUI0 Muc68E PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0031939|UniProtKB=Q9I7N9 Q9I7N9 CT42497 PTHR11616:SF337 SODIUM/CHLORIDE DEPENDENT TRANSPORTER BLOATED TUBULES, ISOFORM B-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;glycine transmembrane transporter activity#GO:0015187 glycine transport#GO:0015816;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;establishment of localization#GO:0051234;import into cell#GO:0098657;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 DROME|FlyBase=FBgn0011202|UniProtKB=P48608 P48608 dia PTHR45691:SF6 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003 actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0034659|UniProtKB=Q9W2D0 Q9W2D0 Dmel\CG4021 PTHR11208:SF140 RNA-BINDING PROTEIN RELATED GH05812P-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0038550|UniProtKB=Q9VEF1 Q9VEF1 trabl PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0050413|UniProtKB=Q8MLS3 Q8MLS3 Dmel\CG30413 PTHR37685:SF1 GEO11136P1-RELATED GEO11136P1-RELATED DROME|FlyBase=FBgn0011826|UniProtKB=Q27889 Q27889 Pp2B-14D PTHR45673:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED binding#GO:0005488;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;calcineurin-mediated signaling#GO:0097720;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein phosphatase#PC00195 Wnt signaling pathway#P00057>Calcineurin#P01446 DROME|FlyBase=FBgn0038973|UniProtKB=Q9VD01 Q9VD01 Pebp1 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 DROME|FlyBase=FBgn0028996|UniProtKB=Q9NJB5 Q9NJB5 onecut PTHR14057:SF47 TRANSCRIPTION FACTOR ONECUT HOMEOBOX PROTEIN ONECUT cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0030222|UniProtKB=Q9W2S8 Q9W2S8 Dmel\CG9806 PTHR11533:SF253 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006 primary metabolic process#GO:0044238;peptide catabolic process#GO:0043171;cellular process#GO:0009987;catabolic process#GO:0009056;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0262517|UniProtKB=Q9VW09 Q9VW09 Ltn1 PTHR12389:SF0 ZINC FINGER PROTEIN 294 E3 UBIQUITIN-PROTEIN LIGASE LISTERIN ribonucleoprotein complex binding#GO:0043021;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ribosomal large subunit binding#GO:0043023;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0086367|UniProtKB=Q9W369 Q9W369 t PTHR34180:SF1 PEPTIDASE C45 BETA-ALANYL-DOPAMINE_CARCININE HYDROLASE protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035409|UniProtKB=Q9VZT9 Q9VZT9 Dmel\CG14963 PTHR21163:SF0 PROTEIN G12 GH08205P-RELATED DROME|FlyBase=FBgn0036990|UniProtKB=Q9VPF6 Q9VPF6 mRpL15 PTHR12934:SF15 50S RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 ribosomal protein#PC00202 DROME|FlyBase=FBgn0038206|UniProtKB=Q9VFM9 Q9VFM9 twf PTHR13759:SF10 TWINFILIN TWINFILIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;actin monomer binding#GO:0003785 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;cellular component disassembly#GO:0022411;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of plasma membrane bounded cell projection organization#GO:0120035;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;protein depolymerization#GO:0051261;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;regulation of cell projection assembly#GO:0060491;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;protein-containing complex disassembly#GO:0032984;regulation of actin filament depolymerization#GO:0030834;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903 actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0039437|UniProtKB=Q9VBD9 Q9VBD9 TwdlL PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0000042|UniProtKB=P10987 P10987 Act5C PTHR11937:SF607 ACTIN ACTIN-42A-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cell division#GO:0051301;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Huntington disease#P00029>Actin#P00807 DROME|FlyBase=FBgn0020907|UniProtKB=O16158 O16158 Scp2 PTHR10827:SF106 RETICULOCALBIN CALCIUM-BINDING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0029924|UniProtKB=Q9W3U0 Q9W3U0 Dmel\CG4586 PTHR10909:SF250 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE-RELATED organic acid binding#GO:0043177;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;lipid binding#GO:0008289;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363 monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0026143|UniProtKB=O96989 O96989 Cdc45 PTHR10507:SF0 CDC45-RELATED PROTEIN CELL DIVISION CONTROL PROTEIN 45 HOMOLOG chromatin binding#GO:0003682;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;double-strand break repair#GO:0006302;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;response to stimulus#GO:0050896;cellular component organization#GO:0016043;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;protein-containing complex assembly#GO:0065003;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;double-strand break repair via break-induced replication#GO:0000727;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 DROME|FlyBase=FBgn0047135|UniProtKB=Q8SYY6 Q8SYY6 Dmel\CG32276 PTHR15601:SF0 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 GEO09675P1 endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0037578|UniProtKB=Q9VHS0 Q9VHS0 PNKP PTHR12083:SF9 BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;nucleobase-containing compound kinase activity#GO:0019205;phosphoric ester hydrolase activity#GO:0042578;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;nucleotide phosphatase#PC00173 DROME|FlyBase=FBgn0000577|UniProtKB=P02836 P02836 en PTHR24341:SF9 HOMEOBOX PROTEIN ENGRAILED SEGMENTATION POLARITY HOMEOBOX PROTEIN ENGRAILED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 DROME|FlyBase=FBgn0033989|UniProtKB=Q9V784 Q9V784 CG7639 PTHR12815:SF18 SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane translocase complex#GO:0005742;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 DROME|FlyBase=FBgn0040252|UniProtKB=Q9VGS7 Q9VGS7 Ugt303A1 PTHR48043:SF145 EG:EG0003.4 PROTEIN-RELATED FI06409P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0043578|UniProtKB=Q70PY2 Q70PY2 PGRP-SB1 PTHR11022:SF75 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN SB1-RELATED molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824 response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0010342|UniProtKB=Q7K180 Q7K180 Map60 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0029148|UniProtKB=Q9V3U2 Q9V3U2 NHP2 PTHR23105:SF54 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0037552|UniProtKB=Q9VHV3 Q9VHV3 Dmel\CG7800 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0038853|UniProtKB=Q9VDE9 Q9VDE9 RhoGAP93B PTHR45876:SF8 FI04035P RHO GTPASE-ACTIVATING PROTEIN 39 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0288976|UniProtKB=Q8INF7 Q8INF7 Dnaaf5 PTHR16216:SF11 DYNEIN ASSEMBLY FACTOR 5, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 5 protein binding#GO:0005515;binding#GO:0005488 cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;inner dynein arm assembly#GO:0036159;organelle assembly#GO:0070925;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232 chaperone#PC00072 DROME|FlyBase=FBgn0039079|UniProtKB=Q9VCM1 Q9VCM1 Ir94g PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|Gene_ORFName=CG8652|UniProtKB=A1ZAK0 A1ZAK0 Ugt37C1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 DROME|FlyBase=FBgn0031856|UniProtKB=Q9VM89 Q9VM89 Dmel\CG11322 PTHR23099:SF0 TRANSCRIPTIONAL REGULATOR GERM CELL NUCLEAR ACIDIC PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 HMG box transcription factor#PC00024 DROME|FlyBase=FBgn0036522|UniProtKB=Q9VUS0 Q9VUS0 Phs PTHR24377:SF1046 IP01015P-RELATED FI01202P-RELATED C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0031191|UniProtKB=Q2PDW6 Q2PDW6 Cp110 PTHR13594:SF1 CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 DROME|FlyBase=FBgn0039438|UniProtKB=Q9VBD8 Q9VBD8 TwdlO PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 DROME|FlyBase=FBgn0046879|UniProtKB=A1ZBP9 A1ZBP9 Obp56c PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0261612|UniProtKB=Q24278 Q24278 CngA PTHR45638:SF25 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;monoatomic cation transmembrane transporter activity#GO:0008324;guanyl ribonucleotide binding#GO:0032561;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;transport#GO:0006810;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 ligand-gated ion channel#PC00141;ion channel#PC00133 DROME|FlyBase=FBgn0051902|UniProtKB=Q0E8V6 Q0E8V6 Spn28Da PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0032163|UniProtKB=Q9VL65 Q9VL65 TbCMF46 PTHR45973:SF12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN REGULATORY COMPLEX SUBUNIT 3 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 DROME|FlyBase=FBgn0039303|UniProtKB=A0A140SRF8 A0A140SRF8 Rer1 PTHR10743:SF0 PROTEIN RER1 PROTEIN RER1 protein localization to organelle#GO:0033365;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;transport#GO:0006810;Golgi vesicle transport#GO:0048193 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0037470|UniProtKB=Q9VI58 Q9VI58 Tailor PTHR12271:SF141 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE TAILOR catalytic activity, acting on RNA#GO:0140098;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 nucleotidyltransferase#PC00174 DROME|FlyBase=FBgn0035529|UniProtKB=Q8SZA8 Q8SZA8 Fdx2 PTHR23426:SF65 FERREDOXIN/ADRENODOXIN ADRENODOXIN-LIKE PROTEIN 2, MITOCHONDRIAL cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;metabolic process#GO:0008152 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 DROME|FlyBase=FBgn0285963|UniProtKB=A0A0B4KH77 A0A0B4KH77 BcDNA:GH07466 PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0051081|UniProtKB=Q8IMR6 Q8IMR6 TwdlR PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 DROME|FlyBase=FBgn0086254|UniProtKB=M9PF61 M9PF61 Ar1 PTHR11732:SF506 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE 1B-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0030788|UniProtKB=Q9VXB3 Q9VXB3 Sap30 PTHR13286:SF6 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30L transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0050158|UniProtKB=A1Z6R7 A1Z6R7 Dmel\CG30158 PTHR24070:SF400 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY FI21445P1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 DROME|FlyBase=FBgn0026136|UniProtKB=O96863 O96863 CkIIbeta2 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0053061|UniProtKB=Q86BI6 Q86BI6 Dmel\CG33061 PTHR12454:SF11 TRIMERIC INTRACELLULAR CATION CHANNEL GH25683P passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;cytoplasm#GO:0005737;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0013717|UniProtKB=Q9VVR1 Q9VVR1 not PTHR21646:SF112 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of protein stability#GO:0031647;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cysteine protease#PC00081 DROME|FlyBase=FBgn0034117|UniProtKB=Q7K127 Q7K127 CT24026 PTHR11452:SF66 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;galactosidase#PC00104 DROME|FlyBase=FBgn0043012|UniProtKB=Q9VDC3 Q9VDC3 AP-2sigma PTHR11753:SF6 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-2 COMPLEX SUBUNIT SIGMA transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 DROME|FlyBase=FBgn0283479|UniProtKB=M9PD70 M9PD70 Alp1 PTHR11596:SF96 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0035149|UniProtKB=Q9W0P3 Q9W0P3 MED30 PTHR31705:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259 DROME|FlyBase=FBgn0037661|UniProtKB=Q9VHH7 Q9VHH7 Ada PTHR11409:SF42 ADENOSINE DEAMINASE N6-METHYL-AMP DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleoside catabolic process#GO:0009164;purine nucleoside metabolic process#GO:0042278;purine-containing compound biosynthetic process#GO:0072522 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 DROME|FlyBase=FBgn0036052|UniProtKB=Q9VT59 Q9VT59 Dmel\CG10809 PTHR24197:SF44 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54-RELATED DROME|FlyBase=FBgn0015790|UniProtKB=O18335 O18335 Rab11 PTHR47979:SF137 DRAB11-RELATED RAB11 hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810 recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0027570|UniProtKB=A0A0B4K692 A0A0B4K692 Nep2 PTHR11733:SF224 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0054015|UniProtKB=Q6IIA4 Q6IIA4 BP1006 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 DROME|FlyBase=FBgn0033830|UniProtKB=Q7K4A8 Q7K4A8 Dmel\CG10814 PTHR10696:SF58 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED GAMMA-BUTYROBETAINE DIOXYGENASE-RELATED 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0052281|UniProtKB=Q8IRE4 Q8IRE4 CG32281 PTHR23245:SF44 TRNA METHYLTRANSFERASE TRNA (GUANINE(37)-N(1))-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;mitochondrial RNA modification#GO:1900864;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0000055|UniProtKB=P00334 P00334 Adh PTHR42901:SF2 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 DROME|FlyBase=FBgn0032793|UniProtKB=Q9VIV3 Q9VIV3 Ctu2 PTHR20882:SF14 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA wobble position uridine thiolation#GO:0002143;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA processing factor#PC00147 DROME|FlyBase=FBgn0031976|UniProtKB=Q9VLU1 Q9VLU1 Dmel\CG7367 PTHR11610:SF192 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0031286|UniProtKB=Q9VPU0 Q9VPU0 Dmel\CG3862 PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular process#GO:0009987;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;ribonucleoprotein complex biogenesis#GO:0022613;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;cellular component organization or biogenesis#GO:0071840;mitochondrial ribosome assembly#GO:0061668 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034051|UniProtKB=Q9NKV0 Q9NKV0 Mlf PTHR13105:SF24 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0030872|UniProtKB=Q9VX14 Q9VX14 Ucp4A PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;response to stimulus#GO:0050896;response to cold#GO:0009409;response to temperature stimulus#GO:0009266 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0030339|UniProtKB=Q9VYT8 Q9VYT8 Cyp28c1 PTHR24292:SF84 CYTOCHROME P450 CYTOCHROME P450 28A5-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0039704|UniProtKB=Q9VAG2 Q9VAG2 neo PTHR47327:SF1 FI18240P1-RELATED FI18240P1-RELATED anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 DROME|FlyBase=FBgn0052055|UniProtKB=Q9VT89 Q9VT89 Dmel\CG32055 PTHR45712:SF36 AGAP008170-PA PODOCAN ISOFORM X1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0265351|UniProtKB=Q9VHT4 Q9VHT4 Gfr PTHR11132:SF255 SOLUTE CARRIER FAMILY 35 GDP-FUCOSE TRANSPORTER 1 organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0033598|UniProtKB=Q7K0A2 Q7K0A2 Cpr47Eb PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0031458|UniProtKB=Q9VQG2 Q9VQG2 aph-1 PTHR12889:SF8 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 proteolysis#GO:0006508;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;signal transduction#GO:0007165;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170 DROME|FlyBase=FBgn0033368|UniProtKB=Q8MRD1 Q8MRD1 Dmel\CG13743 PTHR22950:SF708 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;L-amino acid transmembrane transporter activity#GO:0015179 transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 DROME|FlyBase=FBgn0020643|UniProtKB=C0HL63 C0HL63 Lcp65Ab2 PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0034483|UniProtKB=A1ZBR5 A1ZBR5 CG16894 PTHR24067:SF294 UBIQUITIN-CONJUGATING ENZYME E2 PROTEIN CROSSBRONX-LIKE-RELATED acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin ligase complex#GO:0000151;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;chromosome#GO:0005694;chromatin#GO:0000785 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0011653|UniProtKB=Q9VZH2 Q9VZH2 mas PTHR24258:SF148 SERINE PROTEASE-RELATED PROTEIN MASQUERADE serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038651|UniProtKB=Q9VE34 Q9VE34 Epg5 PTHR31139:SF4 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG ECTOPIC P GRANULES PROTEIN 5 HOMOLOG membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764 DROME|FlyBase=FBgn0034092|UniProtKB=A1ZAB8 A1ZAB8 Dmel\CG7798 PTHR11407:SF63 LYSOZYME C LYSOZYME lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824 glycosidase#PC00110 DROME|FlyBase=FBgn0041337|UniProtKB=P82713 P82713 Cyp309a2 PTHR24292:SF84 CYTOCHROME P450 CYTOCHROME P450 28A5-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0004907|UniProtKB=P29310 P29310 14-3-3zeta PTHR18860:SF184 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA scaffold/adaptor protein#PC00226 PI3 kinase pathway#P00048>14-3-3#P01206;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624;Parkinson disease#P00049>14-3-3#P01238 DROME|FlyBase=FBgn0085425|UniProtKB=Q9W2L7 Q9W2L7 CG15655 PTHR11003:SF346 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0283477|UniProtKB=Q9V3W7 Q9V3W7 SF2 PTHR23147:SF76 SERINE/ARGININE RICH SPLICING FACTOR LD40489P membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032397|UniProtKB=Q9VKC8 Q9VKC8 Tom70 PTHR46208:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0052475|UniProtKB=Q9W0V7 Q9W0V7 mthl8 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0027556|UniProtKB=Q9Y115 Q9Y115 CG4928 PTHR19444:SF56 UNC-93 RELATED UNC93-LIKE PROTEIN ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;regulation of system process#GO:0044057;regulation of muscle contraction#GO:0006937;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257;regulation of multicellular organismal process#GO:0051239;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 membrane-bound signaling molecule#PC00152 DROME|FlyBase=FBgn0037970|UniProtKB=Q8INJ3 Q8INJ3 GC2 PTHR45678:SF5 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0027084|UniProtKB=Q9W327 Q9W327 LysRS PTHR42918:SF18 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676 protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 mitochondrion#GO:0005739;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0267912|UniProtKB=Q9VXF1 Q9VXF1 CanA-14F PTHR45673:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED protein binding#GO:0005515;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;calcineurin-mediated signaling#GO:0097720;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 protein phosphatase#PC00195 Wnt signaling pathway#P00057>Calcineurin#P01446 DROME|FlyBase=FBgn0053512|UniProtKB=Q59DX6 Q59DX6 dpr4 PTHR23279:SF41 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 4-RELATED cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252 DROME|FlyBase=FBgn0028939|UniProtKB=Q86BL2 Q86BL2 NimC2 PTHR24047:SF29 FI01909P-RELATED EATER-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0030331|UniProtKB=Q9VYV0 Q9VYV0 Dmel\CG15221 PTHR23511:SF35 SYNAPTIC VESICLE GLYCOPROTEIN 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0005671|UniProtKB=P31409 P31409 Vha55 PTHR43389:SF4 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;proton transmembrane transport#GO:1902600;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0038181|UniProtKB=Q8I0D4 Q8I0D4 tmn PTHR10199:SF119 THROMBOSPONDIN RE20510P structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0031256|UniProtKB=Q9VPQ2 Q9VPQ2 shv PTHR44298:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 binding#GO:0005488;protein binding#GO:0005515 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|FlyBase=FBgn0039332|UniProtKB=Q9VBR3 Q9VBR3 alrm PTHR45617:SF187 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 66 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0040394|UniProtKB=Q9W526 Q9W526 Dmel\CG16903 PTHR10026:SF13 CYCLIN LD24704P cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase modulator#PC00140;kinase activator#PC00138 DROME|FlyBase=FBgn0266722|UniProtKB=Q9VF82 Q9VF82 Trs33 PTHR12817:SF0 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;TRAPP complex#GO:0030008;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;intracellular protein-containing complex#GO:0140535;cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0030395|UniProtKB=Q9VYM3 Q9VYM3 Mks1 PTHR12968:SF4 B9 DOMAIN-CONTAINING TECTONIC-LIKE COMPLEX MEMBER MKS1 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cilium#GO:0005929;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227 structural protein#PC00211 DROME|FlyBase=FBgn0038965|UniProtKB=Q95RA8 Q95RA8 mats PTHR22599:SF74 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR-LIKE 1 molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;hippo signaling#GO:0035329;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase activator#PC00138 DROME|FlyBase=FBgn0016076|UniProtKB=Q9VMS4 Q9VMS4 vri PTHR15284:SF0 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN GH23983P regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;circadian rhythm#GO:0007623;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;rhythmic process#GO:0048511 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0031452|UniProtKB=Q9VQF5 Q9VQF5 Cwc25 PTHR16196:SF0 CELL CYCLE CONTROL PROTEIN CWF25 PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0085374|UniProtKB=A8DYR4 A8DYR4 Dmel\CG34345 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039787|UniProtKB=Q9VA55 Q9VA55 Dmel\CG9702 PTHR11814:SF231 SULFATE TRANSPORTER RE02508P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0039040|UniProtKB=Q9VCS2 Q9VCS2 Dmel\CG13833 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 dehydrogenase#PC00092 DROME|FlyBase=FBgn0028979|UniProtKB=Q9U3V5 Q9U3V5 tio PTHR12487:SF7 TEASHIRT-RELATED PROTEIN TEASHIRT-RELATED DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0264556|UniProtKB=P58957 P58957 Gr39a PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0035519|UniProtKB=Q9VZF1 Q9VZF1 Dmel\CG1309 PTHR12277:SF72 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN BAT5L PROTEIN hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid metabolic process#GO:0006650;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;glycerophospholipid catabolic process#GO:0046475;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464 serine protease#PC00203 DROME|FlyBase=FBgn0039421|UniProtKB=Q9VBF9 Q9VBF9 Nil PTHR47992:SF257 PROTEIN PHOSPHATASE ALPHABET, ISOFORM E phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DPP signaling pathway#P06213>PPM1A#P06289;Activin beta signaling pathway#P06210>PPM1A#P06237;MYO signaling pathway#P06215>PPM1A#P06317;SCW signaling pathway#P06216>PPM1A#P06332;BMP/activin signaling pathway-drosophila#P06211>PPM1A#P06247;GBB signaling pathway#P06214>PPM1A#P06296;ALP23B signaling pathway#P06209>PPM1A#P06226;DPP-SCW signaling pathway#P06212>PPM1A#P06261 DROME|FlyBase=FBgn0035842|UniProtKB=B7Z0D7 B7Z0D7 Setx PTHR10887:SF552 DNA2/NAM7 HELICASE FAMILY HELICASE SENATAXIN RNA binding#GO:0003723;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;macromolecule metabolic process#GO:0043170;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 RNA helicase#PC00032 DROME|FlyBase=FBgn0039170|UniProtKB=Q9VCB1 Q9VCB1 CG13609 PTHR12433:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0014092|UniProtKB=Q9NK57 Q9NK57 anon-35F_36A PTHR13799:SF13 NGG1 INTERACTING FACTOR 3 NIF3-LIKE PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0028402|UniProtKB=Q9VP85 Q9VP85 Polr3E PTHR12069:SF0 DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0039405|UniProtKB=Q8MSE4 Q8MSE4 PIG-P PTHR46346:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220 DROME|FlyBase=FBgn0024314|UniProtKB=Q9VPY2 Q9VPY2 Plap PTHR19849:SF0 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN PHOSPHOLIPASE A2 ACTIVATOR PROTEIN, ISOFORM A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macroautophagy#GO:0016236;proteasomal protein catabolic process#GO:0010498;autophagy#GO:0006914;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0034266|UniProtKB=B7YZJ4 B7YZJ4 Atxn10 PTHR13255:SF1 ATAXIN-10 ATAXIN-10 plasma membrane bounded cell projection assembly#GO:0120031;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;cilium organization#GO:0044782;system development#GO:0048731;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468 dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;cytosol#GO:0005829;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038597|UniProtKB=Q9VE98 Q9VE98 Dmel\CG8064 PTHR19853:SF0 WD REPEAT CONTAINING PROTEIN 3 WDR3 WD REPEAT-CONTAINING PROTEIN 3 RNA binding#GO:0003723;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0005411|UniProtKB=Q24562 Q24562 U2af50 PTHR23139:SF9 RNA-BINDING PROTEIN SPLICING FACTOR U2AF 65 KDA SUBUNIT nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002;binding#GO:0005488;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;nuclear speck#GO:0016607;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0035165|UniProtKB=Q9W0M4 Q9W0M4 Dmel\CG13887 PTHR12701:SF20 BCR-ASSOCIATED PROTEIN, BAP ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN protein carrier activity#GO:0140597;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104 macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;positive regulation of metabolic process#GO:0009893;protein transport#GO:0015031;positive regulation of protein metabolic process#GO:0051247;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;transport#GO:0006810;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;protein metabolic process#GO:0019538;localization#GO:0051179;regulation of protein catabolic process#GO:0042176;ERAD pathway#GO:0036503;positive regulation of protein catabolic process#GO:0045732;response to endoplasmic reticulum stress#GO:0034976;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0261243|UniProtKB=Q8IRH1 Q8IRH1 Psa PTHR11533:SF174 PROTEASE M1 ZINC METALLOPROTEASE PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 catabolic process#GO:0009056;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0034996|UniProtKB=Q9W189 Q9W189 anon-WO0170980.148 PTHR24238:SF58 G-PROTEIN COUPLED RECEPTOR FI22604P1 molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0010750|UniProtKB=Q9VN55 Q9VN55 atms PTHR23188:SF12 RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;RNA polymerase binding#GO:0070063;chromatin binding#GO:0003682;enzyme binding#GO:0019899 membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0037513|UniProtKB=Q9VI04 Q9VI04 pyd3 PTHR43674:SF17 NITRILASE C965.09-RELATED BETA-UREIDOPROPIONASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 Pyrimidine Metabolism#P02771>Beta-Ureidopropionase#P03127 DROME|FlyBase=FBgn0004842|UniProtKB=P25931 P25931 RYa-R PTHR24238:SF73 G-PROTEIN COUPLED RECEPTOR RYAMIDE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030186|UniProtKB=Q9W2X5 Q9W2X5 Dmel\CG2962 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0262524|UniProtKB=Q9VTZ2 Q9VTZ2 ver PTHR13989:SF33 REPLICATION PROTEIN A-RELATED PROTEIN VERROCCHIO binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565 DROME|FlyBase=FBgn0005561|UniProtKB=O16117 O16117 sv PTHR45636:SF43 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX POX-NEURO PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0037783|UniProtKB=Q9VH31 Q9VH31 Npc2c PTHR11306:SF36 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NIEMANN-PICK TYPE C-2C-RELATED lipid binding#GO:0008289;steroid binding#GO:0005496;binding#GO:0005488;sterol binding#GO:0032934 transport#GO:0006810;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid transport#GO:0006869 DROME|FlyBase=FBgn0086695|UniProtKB=Q9VNA8 Q9VNA8 hd PTHR12972:SF0 DOWNSTREAM NEIGHBOR OF SON PROTEIN DOWNSTREAM NEIGHBOR OF SON cellular process#GO:0009987;DNA replication#GO:0006260;cell cycle process#GO:0022402;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0034451|UniProtKB=A1ZBM2 A1ZBM2 Tbcb PTHR18916:SF97 DYNACTIN 1-RELATED MICROTUBULE-BINDING TUBULIN-FOLDING COFACTOR B protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule end#GO:1990752;cell cortex#GO:0005938;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 chaperone#PC00072 DROME|FlyBase=FBgn0028491|UniProtKB=X2JCG8 X2JCG8 CG32780 PTHR11654:SF655 OLIGOPEPTIDE TRANSPORTER-RELATED OLIGOPEPTIDE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916 localization#GO:0051179;dipeptide transport#GO:0042938;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;oligopeptide transport#GO:0006857;transport#GO:0006810;import across plasma membrane#GO:0098739;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0038463|UniProtKB=Q9VEQ0 Q9VEQ0 Dmel\CG3534 PTHR10196:SF57 SUGAR KINASE XYLULOSE KINASE carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 kinase#PC00137;carbohydrate kinase#PC00065 Ascorbate degradation#P02729>L-xylulose kinase#P02849 DROME|FlyBase=FBgn0050295|UniProtKB=Q9W2Q7 Q9W2Q7 Ipk1 PTHR14456:SF2 INOSITOL POLYPHOSPHATE KINASE 1 INOSITOL-PENTAKISPHOSPHATE 2-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase#PC00137 DROME|FlyBase=FBgn0031776|UniProtKB=Q9VMH8 Q9VMH8 Pfdn1 PTHR20903:SF0 PREFOLDIN SUBUNIT 1-RELATED PREFOLDIN SUBUNIT 1 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 DROME|FlyBase=FBgn0011785|UniProtKB=Q9VC96 Q9VC96 BRWD3 PTHR16266:SF17 WD REPEAT DOMAIN 9 BRWD3 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0015625|UniProtKB=Q9I7I0 Q9I7I0 CycB3 PTHR10177:SF629 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B3 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase activator#PC00138 DROME|FlyBase=FBgn0033400|UniProtKB=Q7K0K1 Q7K0K1 Dmel\CG2063 PTHR13464:SF0 TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP SAP30-BINDING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0027794|UniProtKB=Q9W592 Q9W592 Lrpprc2 PTHR46669:SF2 LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL EG:BACN32G11.3 PROTEIN RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|Gene_ORFName=Dmel_CG46504|UniProtKB=A0ACD4DAU4 A0ACD4DAU4 CG46504 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 DROME|FlyBase=FBgn0261085|UniProtKB=Q9VYE1 Q9VYE1 Syt12 PTHR10024:SF252 SYNAPTOTAGMIN SYNAPTOTAGMIN-12 SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299;protein binding#GO:0005515 transport#GO:0006810;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;localization#GO:0051179;regulation of secretion#GO:0051046;establishment of localization#GO:0051234;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 DROME|FlyBase=FBgn0031189|UniProtKB=Q9VR56 Q9VR56 Trmt10A PTHR13563:SF13 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA (GUANINE(9)-N(1))-METHYLTRANSFERASE TRMT10A RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0033769|UniProtKB=Q8T0N5 Q8T0N5 Dmel\CG8768 PTHR11092:SF0 SUGAR NUCLEOTIDE EPIMERASE RELATED EPIMERASE FAMILY PROTEIN SDR39U1 epimerase/racemase#PC00096 DROME|FlyBase=FBgn0034529|UniProtKB=A1ZBW7 A1ZBW7 FAM21 PTHR21669:SF1 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS WASH COMPLEX SUBUNIT 2 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033757|UniProtKB=Q0E9A5 Q0E9A5 muskelin PTHR15526:SF5 MUSKELIN MUSKELIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0034069|UniProtKB=A1ZA86 A1ZA86 Dmel\CG8401 PTHR33539:SF1 UPF0764 PROTEIN C16ORF89 UPF0764 PROTEIN C16ORF89 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0030889|UniProtKB=A8JUM9 A8JUM9 Dmel\CG15373 PTHR20929:SF12 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED AT08232P binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929 DROME|FlyBase=FBgn0030109|UniProtKB=Q9W366 Q9W366 Dmel\CG12121 PTHR21229:SF2 LUNG SEVEN TRANSMEMBRANE RECEPTOR RE59932P intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0034135|UniProtKB=A1ZAH3 A1ZAH3 Syn2 PTHR10554:SF1 SYNTROPHIN FI16515P1 membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0259998|UniProtKB=Q9W5U8 Q9W5U8 anon-38C.22 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0086895|UniProtKB=A1Z9L3 A1Z9L3 pea PTHR18934:SF277 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0265595|UniProtKB=Q8IR92 Q8IR92 CG42683 PTHR23055:SF167 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 DROME|FlyBase=FBgn0031379|UniProtKB=Q9VQ60 Q9VQ60 Dmel\CG7289 PTHR31386:SF2 UNCHARACTERIZED PROTEIN KIAA2013 RIKEN CDNA 2510039O18 GENE LIKE DROME|FlyBase=FBgn0034141|UniProtKB=A1ZAI1 A1ZAI1 Dolk PTHR13205:SF15 TRANSMEMBRANE PROTEIN 15-RELATED DOLICHOL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0029769|UniProtKB=Q9W4B8 Q9W4B8 frma PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0034588|UniProtKB=Q9W2L6 Q9W2L6 Dmel\CG9394 PTHR22958:SF43 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 catabolic process#GO:0009056;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0035176|UniProtKB=Q9W0L3 Q9W0L3 mat PTHR21163:SF0 PROTEIN G12 GH08205P-RELATED DROME|FlyBase=FBgn0036670|UniProtKB=Q8IQN9 Q8IQN9 Dmel\CG13029 PTHR22883:SF511 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;establishment of localization#GO:0051234;developmental process#GO:0032502;protein targeting to membrane#GO:0006612;developmental maturation#GO:0021700;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein targeting#GO:0006605;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0028970|UniProtKB=Q9XZ68 Q9XZ68 RabGGTb PTHR11774:SF11 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0027786|UniProtKB=Q9V3Y4 Q9V3Y4 Mtch PTHR10780:SF18 MITOCHONDRIAL CARRIER HOMOLOG LD43650P molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0037656|UniProtKB=Q9VHI3 Q9VHI3 Dmel\CG11986 PTHR13604:SF0 DC12-RELATED ABASIC SITE PROCESSING PROTEIN HMCES damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;catalytic activity#GO:0003824;binding#GO:0005488;lyase activity#GO:0016829;DNA binding#GO:0003677 cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;cellular process#GO:0009987;response to stress#GO:0006950;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;replication fork#GO:0005657;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0036365|UniProtKB=Q9VU76 Q9VU76 cmb PTHR34491:SF158 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED COMBOVER, ISOFORM A DROME|FlyBase=FBgn0267385|UniProtKB=O62619 O62619 Pyk PTHR11817:SF3 PYRUVATE KINASE AT14039P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;pyruvate kinase activity#GO:0004743 nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 DROME|FlyBase=FBgn0031432|UniProtKB=Q9VQD2 Q9VQD2 Cyp309a1 PTHR24292:SF84 CYTOCHROME P450 CYTOCHROME P450 28A5-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0050022|UniProtKB=Q86PD3 Q86PD3 CG30022_CG30023 PTHR43084:SF1 PERSULFIDE DIOXYGENASE ETHE1 PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0031126|UniProtKB=Q9VRB3 Q9VRB3 Cyp6v1 PTHR24292:SF45 CYTOCHROME P450 CYTOCHROME P450 6G1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0034842|UniProtKB=Q9W1S5 Q9W1S5 Prosbeta5R1 PTHR11599:SF246 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0033215|UniProtKB=Q7K1C2 Q7K1C2 Dgat2 PTHR12317:SF0 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0026404|UniProtKB=Q9XYF4 Q9XYF4 Dronc PTHR15034:SF5 DEATH DOMAIN-CONTAINING PROTEIN CRADD CASPASE DRONC regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of apoptotic process#GO:0043065;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0031307|UniProtKB=Q9VPX2 Q9VPX2 MFS3 PTHR11662:SF457 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0035743|UniProtKB=Q9VS21 Q9VS21 Acbp6 PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0086916|UniProtKB=Q9VU52 Q9VU52 snky PTHR21041:SF17 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE DCST1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 single fertilization#GO:0007338;cellular process#GO:0009987;fertilization#GO:0009566;reproductive process#GO:0022414;sperm-egg recognition#GO:0035036;cell recognition#GO:0008037;sexual reproduction#GO:0019953;cell-cell recognition#GO:0009988 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708 DROME|FlyBase=FBgn0287831|UniProtKB=Q94521 Q94521 speck PTHR20905:SF33 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0051999|UniProtKB=Q9V4B8 Q9V4B8 CT7856 PTHR24034:SF200 EGF-LIKE DOMAIN-CONTAINING PROTEIN FI18763P1-RELATED extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0038448|UniProtKB=A0A0B4KHM5 A0A0B4KHM5 Dmel\CG12783 PTHR23511:SF37 SYNAPTIC VESICLE GLYCOPROTEIN 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038209|UniProtKB=Q9VFM3 Q9VFM3 Recs1 PTHR23291:SF131 BAX INHIBITOR-RELATED TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0035486|UniProtKB=Q9VZJ6 Q9VZJ6 Gr64d PTHR21421:SF35 GUSTATORY RECEPTOR GUSTATORY RECEPTOR FOR SUGAR TASTE 64B-RELATED monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0035771|UniProtKB=Q9VS57 Q9VS57 Sec63 PTHR24075:SF0 SEC63 DOMAIN-CONTAINING TRANSLOCATION PROTEIN SEC63 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0029932|UniProtKB=Q9W3S8 Q9W3S8 Dmel\CG4607 PTHR48021:SF89 FAMILY NOT NAMED FI02132P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0259110|UniProtKB=X2JE21 X2JE21 mmd PTHR11905:SF237 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN MIND-MELD, ISOFORM J metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0026175|UniProtKB=Q9VWC4 Q9VWC4 SkpC PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031471|UniProtKB=Q9VQH9 Q9VQH9 c-SPH94 PTHR24256:SF462 TRYPTASE-RELATED LP21446P-RELATED catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0031437|UniProtKB=Q9VQD8 Q9VQD8 Arpc5 PTHR12644:SF5 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;cell migration#GO:0016477;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Integrin signalling pathway#P00034>Arp2/3#P00912 DROME|FlyBase=FBgn0003598|UniProtKB=P20193 P20193 Su(var)3-7 PTHR44029:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0023001|UniProtKB=Q9VS24 Q9VS24 melt PTHR21630:SF10 VEPH-A/MELTED VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1 binding#GO:0005488;anion binding#GO:0043168;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0030625|UniProtKB=Q9VXW9 Q9VXW9 Dmel\CG5877 PTHR13471:SF0 TETRATRICOPEPTIDE-LIKE HELICAL NUCLEAR EXOSOME REGULATOR NRDE2 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523 DROME|FlyBase=FBgn0029827|UniProtKB=Q9W453 Q9W453 SP108 PTHR24253:SF192 TRANSMEMBRANE PROTEASE SERINE CORIN, ISOFORM B-RELATED peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0015773|UniProtKB=Q24567 Q24567 NetA PTHR10574:SF365 NETRIN/LAMININ-RELATED NETRIN-A-RELATED axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;dendrite development#GO:0016358 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 DROME|FlyBase=FBgn0035050|UniProtKB=Q9GU23 Q9GU23 SiaT PTHR46059:SF1 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-(2,6)-SIALYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0033556|UniProtKB=Q9V5Q4 Q9V5Q4 Syf2 PTHR13264:SF5 GCIP-INTERACTING PROTEIN P29 PRE-MRNA-SPLICING FACTOR SYF2 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0034446|UniProtKB=A1ZBK9 A1ZBK9 Arl6 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;organelle assembly#GO:0070925;protein transport#GO:0015031;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein#PC00020 DROME|FlyBase=FBgn0026394|UniProtKB=P81913 P81913 Or24a PTHR21137:SF26 ODORANT RECEPTOR ODORANT RECEPTOR 10A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039444|UniProtKB=Q9VBD2 Q9VBD2 TwdlD PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0051097|UniProtKB=Q9VBT0 Q9VBT0 CG13665 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0037036|UniProtKB=Q9VP95 Q9VP95 Sems PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033234|UniProtKB=Q8MS66 Q8MS66 MFS12 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0019929|UniProtKB=Q9W314 Q9W314 Ser7 PTHR24258:SF144 SERINE PROTEASE-RELATED GH14088P protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0037170|UniProtKB=Q9VNT5 Q9VNT5 Trxr2 PTHR48105:SF37 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN-DISULFIDE REDUCTASE (NADPH) catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209 cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0031428|UniProtKB=Q9VQC4 Q9VQC4 Glyctk PTHR12227:SF0 GLYCERATE KINASE GLYCERATE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 DROME|FlyBase=FBgn0036361|UniProtKB=Q9VU72 Q9VU72 Dmel\CG10154 PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;carbohydrate derivative binding#GO:0097367 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0064766|UniProtKB=Q9XZ12 Q9XZ12 Dmel\CG7600 PTHR28441:SF2 PROTEIN FAM91A1 PROTEIN FAM91A1 DROME|FlyBase=FBgn0039107|UniProtKB=Q9VCJ2 Q9VCJ2 Dmel\CG10300 PTHR10174:SF216 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN-RELATED anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0026562|UniProtKB=O97365 O97365 SPARC PTHR13866:SF14 SPARC OSTEONECTIN BM-40 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0053644|UniProtKB=Q4ABF7 Q4ABF7 Dmel\CG33644 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0033873|UniProtKB=Q7JYA0 Q7JYA0 Dmel\CG6337 PTHR12411:SF1033 CYSTEINE PROTEASE FAMILY C1-RELATED RE20049P-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0029681|UniProtKB=Q9W4P4 Q9W4P4 Dmel\CG15239 PTHR36299:SF3 AGAP008005-PA FI03431P DROME|FlyBase=FBgn0086686|UniProtKB=Q9VFH4 Q9VFH4 l(3)L1231 PTHR16198:SF2 INO80 COMPLEX SUBUNIT D INO80 COMPLEX SUBUNIT D intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0052354|UniProtKB=Q9VSK1 Q9VSK1 CG7159 PTHR10913:SF45 FOLLISTATIN-RELATED AGRIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0028479|UniProtKB=Q9V397 Q9V397 Mtpalpha PTHR43612:SF3 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;transferase complex#GO:1990234;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0010438|UniProtKB=P54622 P54622 mtSSB PTHR10302:SF0 SINGLE-STRANDED DNA-BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;DNA binding#GO:0003677 DNA replication#GO:0006260;regulation of organelle organization#GO:0033043;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;positive regulation of DNA metabolic process#GO:0051054;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of DNA replication#GO:0006275;positive regulation of DNA replication#GO:0045740;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoid#GO:0009295;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645;organelle lumen#GO:0043233 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0013563|UniProtKB=Q9VUC7 Q9VUC7 Pex1 PTHR23077:SF12 AAA-FAMILY ATPASE PEROXISOMAL ATPASE PEX1 ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 peroxisome organization#GO:0007031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;peroxisomal transport#GO:0043574;protein transport#GO:0015031;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;intracellular transport#GO:0046907;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;peroxisome#GO:0005777;cytosol#GO:0005829;microbody#GO:0042579;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0032217|UniProtKB=Q9VKZ7 Q9VKZ7 Q9VKZ7_DROME PTHR31826:SF0 NICALIN NICALIN regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 DROME|FlyBase=FBgn0039019|UniProtKB=Q9VCU6 Q9VCU6 HP1c PTHR22812:SF162 CHROMOBOX PROTEIN CHROMOBOX 3 chromatin binding#GO:0003682;binding#GO:0005488 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038877|UniProtKB=Q9VDC1 Q9VDC1 Dmel\CG3308 PTHR10060:SF48 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 DROME|FlyBase=FBgn0015269|UniProtKB=Q9VBJ2 Q9VBJ2 Nf1 PTHR10194:SF142 RAS GTPASE-ACTIVATING PROTEINS NEUROFIBROMIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 DROME|FlyBase=FBgn0030049|UniProtKB=Q7KVS9 Q7KVS9 Trf4-1 PTHR23092:SF15 POLY(A) RNA POLYMERASE INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0003382|UniProtKB=B7YZF2 B7YZF2 sha PTHR39387:SF2 SHAVENOID, ISOFORM B SHAVENOID, ISOFORM B epidermis development#GO:0008544;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neurogenesis#GO:0022008;hair cell differentiation#GO:0035315;cellular process#GO:0009987;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;post-embryonic development#GO:0009791;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;animal organ morphogenesis#GO:0009887 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938 DROME|FlyBase=FBgn0029823|UniProtKB=Q9W457 Q9W457 Shmt PTHR11680:SF59 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 DROME|FlyBase=FBgn0038438|UniProtKB=Q9VEU2 Q9VEU2 Der-2 PTHR11009:SF32 DER1-LIKE PROTEIN, DERLIN DERLIN cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;signal transduction#GO:0007165;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0036977|UniProtKB=M9NFL7 M9NFL7 cg5665 PTHR11610:SF149 LIPASE FI01450P-RELATED catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0285954|UniProtKB=Q27294 Q27294 caz PTHR23238:SF26 RNA BINDING PROTEIN GH13594P-RELATED RNA binding#GO:0003723;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0053458|UniProtKB=A1ZAG8 A1ZAG8 Dmel\CG33458 PTHR24278:SF36 COAGULATION FACTOR PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine protease#PC00203 DROME|FlyBase=FBgn0038272|UniProtKB=Q9VFE9 Q9VFE9 Dph2 PTHR10762:SF2 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152 DROME|FlyBase=FBgn0032853|UniProtKB=Q9VIN6 Q9VIN6 38C.2 PTHR10334:SF613 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0034442|UniProtKB=A1ZBK6 A1ZBK6 Dmel\CG11257 PTHR46237:SF2 CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER CYTOCHROME B5 REDUCTASE 4 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;superoxide metabolic process#GO:0006801 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 reductase#PC00198 DROME|FlyBase=FBgn0000317|UniProtKB=Q9V3Z6 Q9V3Z6 ck PTHR13140:SF872 MYOSIN MYOSIN VIIAA ISOFORM X1 macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 organelle organization#GO:0006996;actin filament-based movement#GO:0030048;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;sensory organ development#GO:0007423;developmental process#GO:0032502;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;actin filament organization#GO:0007015;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;sensory perception of sound#GO:0007605;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435 actin cytoskeleton#GO:0015629;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0003401|UniProtKB=Q9W1I9 Q9W1I9 shu PTHR46674:SF1 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 protein binding#GO:0005515;binding#GO:0005488;Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;male gamete generation#GO:0048232;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0039053|UniProtKB=Q9VCQ8 Q9VCQ8 Dmel\CG6738 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0261262|UniProtKB=A0A0B4K760 A0A0B4K760 CG31149 PTHR47537:SF6 CUBILIN CUB DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0026206|UniProtKB=M9PH32 M9PH32 mei-P26 PTHR25462:SF311 BONUS, ISOFORM C-RELATED PROTEIN MEIOTIC P26 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0032721|UniProtKB=Q9VJ39 Q9VJ39 pepCG10602 PTHR45726:SF8 LEUKOTRIENE A-4 HYDROLASE LEUKOTRIENE A(4) HYDROLASE peptidase activity#GO:0008233;ether hydrolase activity#GO:0016803;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177 catabolic process#GO:0009056;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;peptide catabolic process#GO:0043171;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0025571|UniProtKB=Q9VEJ1 Q9VEJ1 SF1 PTHR11208:SF45 RNA-BINDING PROTEIN RELATED SPLICING FACTOR 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0051730|UniProtKB=Q8IP77 Q8IP77 Dmel\CG31730 PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 acetyltransferase#PC00038 DROME|FlyBase=FBgn0051665|UniProtKB=Q7KU08 Q7KU08 wry PTHR24044:SF417 NOTCH LIGAND FAMILY MEMBER WEARY, ISOFORM B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0015582|UniProtKB=Q9V3T9 Q9V3T9 dare PTHR11938:SF151 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;steroid biosynthetic process#GO:0006694;cellular process#GO:0009987;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FdxR#P04604 DROME|FlyBase=FBgn0000422|UniProtKB=P05031 P05031 Ddc PTHR11999:SF167 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE AROMATIC-L-AMINO-ACID DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;serotonin biosynthetic process#GO:0042427;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;amine metabolic process#GO:0009308;phenol-containing compound biosynthetic process#GO:0046189;serotonin metabolic process#GO:0042428;catecholamine metabolic process#GO:0006584;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 decarboxylase#PC00089;lyase#PC00144 Nicotine pharmacodynamics pathway#P06587>DDC#P06608;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961;Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400 DROME|FlyBase=FBgn0035537|UniProtKB=Q9VZD2 Q9VZD2 CG11342 PTHR12315:SF1 BICOID-INTERACTING PROTEIN RELATED RNA 5'-MONOPHOSPHATE METHYLTRANSFERASE methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule metabolic process#GO:0060255;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0053198|UniProtKB=Q86BE9 Q86BE9 pen-2 PTHR16318:SF1 GAMMA-SECRETASE SUBUNIT PEN-2 GAMMA-SECRETASE SUBUNIT PEN-2 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 Alzheimer disease-amyloid secretase pathway#P00003>Pen-2#P00089;Alzheimer disease-presenilin pathway#P00004>Pen-2#P00149 DROME|FlyBase=FBgn0051265|UniProtKB=Q9VEM9 Q9VEM9 CG5233 PTHR24260:SF138 AT07769P-RELATED IP10340P-RELATED DROME|FlyBase=FBgn0053124|UniProtKB=Q9VQ85 Q9VQ85 CG33124-PB PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0030386|UniProtKB=Q9VYN3 Q9VYN3 Dmel\CG2574 PTHR24068:SF291 UBIQUITIN-CONJUGATING ENZYME E2 AT30415P-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0042135|UniProtKB=Q7JUR6 Q7JUR6 Gdap2 PTHR11106:SF72 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2 DROME|FlyBase=FBgn0035444|UniProtKB=Q9VZP9 Q9VZP9 Dmel\CG12012 PTHR13551:SF1 BRAIN PROTEIN I3 MEMBRANE PROTEIN BRI3 DROME|FlyBase=FBgn0039261|UniProtKB=Q9VBZ5 Q9VBZ5 Ythdf PTHR12357:SF140 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517;RNA binding#GO:0003723 positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032493|UniProtKB=Q9VK13 Q9VK13 Mabi PTHR23334:SF72 CCAAT/ENHANCER BINDING PROTEIN PROTEIN MABIKI sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0053978|UniProtKB=Q2PDM3 Q2PDM3 FBgn0053978 PTHR39072:SF2 RE48511P 63 KDA SPERM FLAGELLAR MEMBRANE PROTEIN DROME|FlyBase=FBgn0025740|UniProtKB=Q9V4A7 Q9V4A7 PlexB PTHR22625:SF71 PLEXIN PLEXIN-B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 positive regulation of nervous system development#GO:0051962;cell projection organization#GO:0030030;cell differentiation#GO:0030154;signaling#GO:0023052;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;regulation of multicellular organismal development#GO:2000026;positive regulation of axonogenesis#GO:0050772;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;negative regulation of cell adhesion#GO:0007162;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell morphogenesis#GO:0000902;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell development#GO:0048468;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;positive regulation of cell development#GO:0010720;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon guidance#GO:0007411;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;neuron projection morphogenesis#GO:0048812;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0038862|UniProtKB=Q9VDD8 Q9VDD8 Usp8 PTHR21646:SF107 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;regulation of protein stability#GO:0031647;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of canonical Wnt signaling pathway#GO:0060828;endomembrane system organization#GO:0010256;intracellular signaling cassette#GO:0141124;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;positive regulation of response to stimulus#GO:0048584;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 cysteine protease#PC00081 DROME|FlyBase=FBgn0024542|UniProtKB=Q9U9Q2 Q9U9Q2 Neos PTHR23295:SF6 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED NEOSIN, ISOFORM A transcription cofactor#PC00217 DROME|FlyBase=FBgn0267821|UniProtKB=P11420 P11420 da PTHR11793:SF13 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR PROTEIN DAUGHTERLESS cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 chromosome#GO:0005694;chromatin#GO:0000785;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0032055|UniProtKB=Q9VLJ7 Q9VLJ7 Sgp PTHR11011:SF60 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0038532|UniProtKB=A0A0B4KHA8 A0A0B4KHA8 Dmel\CG14322 PTHR14435:SF2 ZINC FINGER PROTEIN 106 ZINC FINGER PROTEIN 106 DROME|FlyBase=FBgn0036481|UniProtKB=Q9VUL4 Q9VUL4 Dmel\CG16959 PTHR21177:SF8 IP06524P-RELATED GH11627P DROME|FlyBase=FBgn0259139|UniProtKB=Q9VGH5 Q9VGH5 glo PTHR13976:SF76 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED AT27789P protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0031942|UniProtKB=Q9VLX9 Q9VLX9 Dmel\CG7203 PTHR12336:SF0 ADULT CUTICLE PROTEIN 1-RELATED ADULT CUTICLE PROTEIN 1-RELATED DROME|FlyBase=FBgn0040337|UniProtKB=Q9W5B6 Q9W5B6 CG3021 PTHR11933:SF10 TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble position uridine thiolation#GO:0002143;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;mitochondrial gene expression#GO:0140053;mitochondrial RNA modification#GO:1900864;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0051933|UniProtKB=Q9VQ50 Q9VQ50 gi22945479 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED DROME|FlyBase=FBgn0001208|UniProtKB=P17276 P17276 Hn PTHR11473:SF46 AROMATIC AMINO ACID HYDROXYLASE PROTEIN HENNA oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;phenol-containing compound biosynthetic process#GO:0046189;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;serotonin metabolic process#GO:0042428;catecholamine metabolic process#GO:0006584;phenol-containing compound metabolic process#GO:0018958;indole-containing compound metabolic process#GO:0042430;carboxylic acid biosynthetic process#GO:0046394;aromatic amino acid biosynthetic process#GO:0009073;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;serotonin biosynthetic process#GO:0042427;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032084|UniProtKB=Q9VLG1 Q9VLG1 Dmel\CG13101 PTHR12242:SF49 OS02G0130600 PROTEIN-RELATED IP08657P-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0051668|UniProtKB=Q8IPY0 Q8IPY0 CG31668-PB PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0011603|UniProtKB=Q9VR07 Q9VR07 ine PTHR11616:SF303 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER INE transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;glycine transport#GO:0015816;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 DROME|FlyBase=FBgn0053299|UniProtKB=Q7KTG1 Q7KTG1 Dmel\CG33299 PTHR47771:SF13 LD27203P-RELATED HDC01644 DROME|FlyBase=FBgn0013684|UniProtKB=P18932 P18932 mt:ND5 PTHR42829:SF4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0033731|UniProtKB=A1Z8Z7 A1Z8Z7 Cpr49Ah PTHR10380:SF109 CUTICLE PROTEIN CUTICULAR PROTEIN 49AH extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0036728|UniProtKB=Q9VVH5 Q9VVH5 UQCR-Q PTHR12119:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C CYTOCHROME B-C1 COMPLEX SUBUNIT 8 electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex III#GO:0045275;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494 oxidoreductase#PC00176 DROME|FlyBase=FBgn0039070|UniProtKB=Q9VCN4 Q9VCN4 wam PTHR21694:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 DROME|FlyBase=FBgn0014031|UniProtKB=Q9W3Z3 Q9W3Z3 Agxt PTHR21152:SF40 AMINOTRANSFERASE CLASS V ALANINE--GLYOXYLATE AMINOTRANSFERASE transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;monocarboxylic acid catabolic process#GO:0072329;aldehyde catabolic process#GO:0046185;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 transferase#PC00220;transaminase#PC00216 DROME|FlyBase=FBgn0032684|UniProtKB=Q9VJ81 Q9VJ81 Ugt301D1 PTHR48043:SF158 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 DROME|FlyBase=FBgn0052984|UniProtKB=Q86BL8 Q86BL8 gi21430910 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0037411|UniProtKB=Q9VNM4 Q9VNM4 Osi3 PTHR21879:SF3 FI03362P-RELATED-RELATED FI03378P membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038129|UniProtKB=Q9VFX6 Q9VFX6 TBC1D5 PTHR22957:SF337 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 5 GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;retromer complex#GO:0030904;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0028847|UniProtKB=Q9VJW5 Q9VJW5 Dmel\CG9014 PTHR15315:SF26 RING FINGER PROTEIN 41, 151 E3 UBIQUITIN-PROTEIN LIGASE NRDP1 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 DROME|FlyBase=FBgn0041238|UniProtKB=Q9W2B1 Q9W2B1 Gr58b PTHR21143:SF135 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 58A-RELATED dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;neuron projection#GO:0043005;cell body#GO:0044297;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0033474|UniProtKB=A0A0B4LF16 A0A0B4LF16 Dmel\CG1407 PTHR22883:SF147 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031248|UniProtKB=Q9VPN7 Q9VPN7 anon-WO0140519.112 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0086676|UniProtKB=Q9GQQ0 Q9GQQ0 spin PTHR23505:SF79 SPINSTER PROTEIN SPINSTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0031517|UniProtKB=Q9VQN6 Q9VQN6 Dmel\CG15406 PTHR48021:SF33 FAMILY NOT NAMED AT22075P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0031335|UniProtKB=Q9VQ04 Q9VQ04 28557659 PTHR18901:SF48 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 DROME|FlyBase=FBgn0053920|UniProtKB=Q4AB20 Q4AB20 Dmel\CG33920 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0035779|UniProtKB=Q9VS66 Q9VS66 Dmel\CG8562 PTHR11705:SF140 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI02848P-RELATED metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0031970|UniProtKB=Q9VLU7 Q9VLU7 Dmel\CG7227 PTHR11923:SF93 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 GH07959P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0013997|UniProtKB=Q94887 Q94887 Nrx-IV PTHR15036:SF96 PIKACHURIN-LIKE PROTEIN NEUREXIN-4 multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0016977|UniProtKB=Q8SX83 Q8SX83 spen PTHR23189:SF48 RNA RECOGNITION MOTIF-CONTAINING MSX2-INTERACTING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of DNA-templated transcription#GO:0006355 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0027342|UniProtKB=Q9NBW1 Q9NBW1 fz4 PTHR11309:SF99 FRIZZLED FRIZZLED-4 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147 non-canonical Wnt signaling pathway#GO:0035567;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 DROME|FlyBase=FBgn0035767|UniProtKB=Q9VS51 Q9VS51 Cln7 PTHR23510:SF82 INNER MEMBRANE TRANSPORT PROTEIN YAJR CLN7, ISOFORM A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0030551|UniProtKB=Q9VY49 Q9VY49 Dmel\CG11674 PTHR39069:SF4 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A LD24340P DROME|FlyBase=FBgn0029672|UniProtKB=Q9W4R1 Q9W4R1 Dmel\CG2875 PTHR12455:SF0 NUCLEOLAR COMPLEX PROTEIN 4 NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0086359|UniProtKB=Q9VH19 Q9VH19 Invadolysin PTHR10942:SF0 LEISHMANOLYSIN-LIKE PEPTIDASE LEISHMANOLYSIN-LIKE PEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0032388|UniProtKB=Q95TU2 Q95TU2 Dmel\CG6686 PTHR14152:SF5 SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;ribonucleoprotein complex biogenesis#GO:0022613;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0004583|UniProtKB=Q07436 Q07436 ex PTHR13429:SF5 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY PROTEIN EXPANDED molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 DROME|FlyBase=FBgn0039301|UniProtKB=Q9VBU8 Q9VBU8 Nup37 PTHR22806:SF0 NUCLEOPORIN NUP37 P37 -RELATED NUCLEOPORIN NUP37 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0067052|UniProtKB=Q8IRK9 Q8IRK9 Rab9D PTHR47980:SF101 LD44762P IP08727P-RELATED secretion by cell#GO:0032940;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;export from cell#GO:0140352;endocytic recycling#GO:0032456;endosomal transport#GO:0016197;exocytosis#GO:0006887;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;endosome#GO:0005768;intracellular organelle#GO:0043229;trans-Golgi network transport vesicle#GO:0030140;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0002590|UniProtKB=Q24186 Q24186 RpS5a PTHR11205:SF18 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;binding#GO:0005488 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0035656|UniProtKB=M9PEA4 M9PEA4 Dmel\CG10479 PTHR15832:SF2 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG SH2 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0085484|UniProtKB=Q7KUC2 Q7KUC2 Pdxk PTHR10534:SF2 PYRIDOXAL KINASE PYRIDOXAL KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122;Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121 DROME|FlyBase=FBgn0031053|UniProtKB=Q9VWE5 Q9VWE5 Dmel\CG14223 PTHR39947:SF1 IP19862P IP19862P DROME|FlyBase=FBgn0051065|UniProtKB=A8JPJ8 A8JPJ8 ppk31 PTHR11690:SF184 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 31 ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0014395|UniProtKB=Q9VR52 Q9VR52 tilB PTHR18849:SF21 LEUCINE RICH REPEAT PROTEIN DYNEIN AXONEMAL ASSEMBLY FACTOR 11 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033548|UniProtKB=Q9V5P6 Q9V5P6 Nop10 PTHR13305:SF0 RIBOSOME BIOGENESIS PROTEIN NOP10 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;snRNA processing#GO:0016180;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0027615|UniProtKB=Q9Y171 Q9Y171 OXA1L PTHR12428:SF66 OXA1 MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0029084|UniProtKB=Q9U599 Q9U599 gom PTHR22133:SF2 AT01821P-RELATED AT01821P-RELATED DROME|FlyBase=FBgn0039459|UniProtKB=Q9VBB3 Q9VBB3 IntS12 PTHR13415:SF2 NUCLEAR FACTOR-RELATED INTEGRATOR COMPLEX SUBUNIT 12 macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;integrator complex#GO:0032039;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DROME|FlyBase=FBgn0034277|UniProtKB=Q7K110 Q7K110 OstDelta PTHR12640:SF0 RIBOPHORIN II DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0020510|UniProtKB=A0A0B4K774 A0A0B4K774 Abi PTHR10460:SF68 ABL INTERACTOR FAMILY MEMBER ABELSON INTERACTING PROTEIN, ISOFORM D signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;nervous system development#GO:0007399;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;neuron migration#GO:0001764;multicellular organism development#GO:0007275 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin-based cell projection#GO:0098858;cell leading edge#GO:0031252;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;lamellipodium#GO:0030027 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036035|UniProtKB=Q9VT38 Q9VT38 Dmel\CG18178 PTHR12661:SF5 PETER PAN-RELATED SUPPRESSOR OF SWI4 1 HOMOLOG RNA binding#GO:0003723;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;preribosome, large subunit precursor#GO:0030687;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0052666|UniProtKB=Q0KHT7 Q0KHT7 Drak PTHR24342:SF12 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0038795|UniProtKB=Q9VDM7 Q9VDM7 Tmlh PTHR10696:SF51 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydroxylase#PC00122 DROME|FlyBase=FBgn0038074|UniProtKB=Q9VG42 Q9VG42 Gnmt PTHR16458:SF2 GLYCINE N-METHYLTRANSFERASE GLYCINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741 sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carbohydrate derivative metabolic process#GO:1901135;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;methyltransferase#PC00155 DROME|FlyBase=FBgn0283451|UniProtKB=Q24206 Q24206 br PTHR23110:SF112 BTB DOMAIN TRANSCRIPTION FACTOR BROAD-COMPLEX CORE PROTEIN ISOFORM 6 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036309|UniProtKB=Q8MQJ8 Q8MQJ8 Hip1 PTHR10407:SF15 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN INTERACTING PROTEIN 1 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;protein-membrane adaptor activity#GO:0043495;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981 import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;transport#GO:0006810;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;localization#GO:0051179;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 cell periphery#GO:0071944;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;clathrin-coated vesicle#GO:0030136;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0051546|UniProtKB=Q9VNF4 Q9VNF4 Dmel\CG31546 PTHR43975:SF6 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED DROME|FlyBase=FBgn0030725|UniProtKB=Q9VXJ8 Q9VXJ8 Dmel\CG8958 PTHR23011:SF41 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4-LIKE DROME|FlyBase=FBgn0038976|UniProtKB=Q9VCZ8 Q9VCZ8 Pfdn5 PTHR12674:SF2 PREFOLDIN SUBUNIT 5 PREFOLDIN SUBUNIT 5 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0038576|UniProtKB=Q9VEC3 Q9VEC3 Arp5 PTHR11937:SF16 ACTIN ACTIN-RELATED PROTEIN 5 enzyme regulator activity#GO:0030234;structural molecule activity#GO:0005198;molecular function regulator activity#GO:0098772;structural constituent of cytoskeleton#GO:0005200 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Ino80 complex#GO:0031011 actin and actin related protein#PC00039 DROME|FlyBase=FBgn0015230|UniProtKB=P53403 P53403 Glut3 PTHR48021:SF102 FAMILY NOT NAMED GH07001P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0037573|UniProtKB=Q9VHS8 Q9VHS8 CG7483 PTHR47958:SF26 ATP-DEPENDENT RNA HELICASE DBP3 EUKARYOTIC INITIATION FACTOR 4A-III macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 DROME|FlyBase=FBgn0026079|UniProtKB=Q9W4M9 Q9W4M9 Nsun2 PTHR22808:SF1 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(34)-C(5))-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA methyltransferase activity#GO:0008175;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 RNA metabolic process#GO:0016070;methylation#GO:0032259;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;tRNA wobble base modification#GO:0002097;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;tRNA methylation#GO:0030488;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;mitochondrial large ribosomal subunit assembly#GO:1902775;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;mitochondrial ribosome assembly#GO:0061668;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0063497|UniProtKB=A1ZB68 A1ZB68 GstE3 PTHR43969:SF4 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED FI01423P-RELATED catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 DROME|FlyBase=FBgn0033602|UniProtKB=A1Z8H6 A1Z8H6 Cpr47Ee PTHR10380:SF230 CUTICLE PROTEIN CUTICULAR PROTEIN 47EE-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0033500|UniProtKB=A1Z863 A1Z863 Csgalnact PTHR12369:SF45 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0051013|UniProtKB=Q9VA50 Q9VA50 Dmel\CG31013 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0037546|UniProtKB=Q9VHW1 Q9VHW1 mAChR-B PTHR24247:SF191 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR, B-TYPE, ISOFORM A signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;molecular transducer activity#GO:0060089;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;acetylcholine receptor activity#GO:0015464 signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 DROME|FlyBase=FBgn0010520|UniProtKB=Q9VL75 Q9VL75 Bka PTHR12416:SF2 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DROME|FlyBase=FBgn0032753|UniProtKB=Q8SXE1 Q8SXE1 c-SPH64 PTHR24260:SF140 AT07769P-RELATED RH69521P-RELATED DROME|FlyBase=FBgn0035812|UniProtKB=Q9VSA4 Q9VSA4 CG7457 PTHR46358:SF1 TONSOKU-LIKE PROTEIN TONSOKU-LIKE PROTEIN response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0029756|UniProtKB=Q9W4D1 Q9W4D1 BEST:LD39762 PTHR13677:SF0 LD41638P LD41638P guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;recycling endosome#GO:0055037;intracellular organelle#GO:0043229;endosome#GO:0005768 DROME|FlyBase=FBgn0039328|UniProtKB=Q9VBS0 Q9VBS0 CHKov2 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0261049|UniProtKB=Q9VHB5 Q9VHB5 Vps45 PTHR11679:SF3 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0020640|UniProtKB=P91942 P91942 Lcp65Ae PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0051550|UniProtKB=A0A0B4KF34 A0A0B4KF34 CG12167 PTHR23340:SF0 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0034033|UniProtKB=A1ZA28 A1ZA28 Dmel\CG8204 PTHR13483:SF11 BOX C_D SNORNA PROTEIN 1-RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component assembly#GO:0022607;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DROME|FlyBase=FBgn0052750|UniProtKB=P83548 P83548 CG32750 PTHR10609:SF28 BIOTINIDASE-RELATED CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;metabolic process#GO:0008152;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 hydrolase#PC00121 DROME|FlyBase=FBgn0030051|UniProtKB=Q7K3Y1 Q7K3Y1 spirit PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0033186|UniProtKB=Q8MSB3 Q8MSB3 Dmel\CG1602 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0002734|UniProtKB=Q01071 Q01071 E(spl)mdelta-HLH PTHR10985:SF12 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED ENHANCER OF SPLIT M3 PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 DROME|FlyBase=FBgn0046885|UniProtKB=Q8IMN5 Q8IMN5 Gr98d PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED cell body#GO:0044297;neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039108|UniProtKB=Q9VCJ0 Q9VCJ0 Dmel\CG10232 PTHR24260:SF144 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED Toll pathway-drosophila#P06217>SPE#P06340 DROME|FlyBase=FBgn0001296|UniProtKB=C8VV48 C8VV48 kar PTHR11360:SF251 MONOCARBOXYLATE TRANSPORTER KARMOISIN, ISOFORM B transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0261625|UniProtKB=Q1RL13 Q1RL13 Gls PTHR12544:SF52 GLUTAMINASE GLUTAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 hydrolase#PC00121 DROME|FlyBase=FBgn0025684|UniProtKB=Q9VQZ7 Q9VQZ7 MFS18 PTHR11662:SF279 SOLUTE CARRIER FAMILY 17 VOLTAGE-GATED PURINE NUCLEOTIDE UNIPORTER SLC17A9 nitrogen compound transport#GO:0071705;transport#GO:0006810;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;localization#GO:0051179;organophosphate ester transport#GO:0015748;establishment of localization#GO:0051234 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0003016|UniProtKB=Q27421 Q27421 osp PTHR17271:SF1 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN PROTEIN OUTSPREAD binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0032404|UniProtKB=Q9VKC1 Q9VKC1 RpL7-like PTHR11524:SF58 60S RIBOSOMAL PROTEIN L7 IP16805P structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 DROME|FlyBase=FBgn0039760|UniProtKB=Q9VA86 Q9VA86 Dmel\CG9682 PTHR47372:SF11 DAUER UP-REGULATED-RELATED RE19971P DROME|FlyBase=FBgn0016059|UniProtKB=Q7KK54 Q7KK54 Sema1b PTHR11036:SF131 SEMAPHORIN MIP07328P signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;axon development#GO:0061564;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 DROME|FlyBase=FBgn0032231|UniProtKB=Q9VKY0 Q9VKY0 Oser1 PTHR31383:SF2 OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1 OXIDATIVE STRESS-RESPONSIVE SERINE-RICH PROTEIN 1 DROME|FlyBase=FBgn0024740|UniProtKB=Q9VKR5 Q9VKR5 Lip2 PTHR11005:SF145 LYSOSOMAL ACID LIPASE-RELATED LIPASE-RELATED catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 hydrolase#PC00121;lipase#PC00143 DROME|FlyBase=FBgn0031426|UniProtKB=Q9VQC2 Q9VQC2 Dmel\CG18641 PTHR11610:SF174 LIPASE MIP30168P hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0011763|UniProtKB=Q24318 Q24318 Dp PTHR12548:SF9 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0011745|UniProtKB=P45889 P45889 Arp1 PTHR11937:SF155 ACTIN ACTIN-RELATED PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;structural constituent of cytoskeleton#GO:0005200;cytoskeletal adaptor activity#GO:0008093;protein-membrane adaptor activity#GO:0043495;structural molecule activity#GO:0005198 microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;nuclear migration#GO:0007097 actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 DROME|FlyBase=FBgn0036545|UniProtKB=Q9VUV6 Q9VUV6 GXIVsPLA2 PTHR12824:SF8 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GXIVSPLA2, ISOFORM A hydrolase#PC00121;lipase#PC00143;phospholipase#PC00186 DROME|FlyBase=FBgn0010395|UniProtKB=Q27591 Q27591 Itgbn PTHR10082:SF59 INTEGRIN BETA SUBUNIT INTEGRIN BETA-NU protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;biological regulation#GO:0065007;cell migration#GO:0016477;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627 membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;focal adhesion#GO:0005925;signaling receptor complex#GO:0043235;cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 DROME|FlyBase=FBgn0039855|UniProtKB=Q9V9W5 Q9V9W5 Dmel\CG1638 PTHR12655:SF10 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL hydrolase activity#GO:0016787;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;deacylase activity#GO:0160215;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 DROME|FlyBase=FBgn0039977|UniProtKB=Q95RI7 Q95RI7 Spf30 PTHR13681:SF26 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0031469|UniProtKB=Q9VQH7 Q9VQH7 Dmel\CG18558 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;galactosyltransferase activity#GO:0008378 transferase#PC00220 DROME|FlyBase=FBgn0086711|UniProtKB=Q9VJQ7 Q9VJQ7 mol PTHR31158:SF10 DUAL OXIDASE 2 LD27791P membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 DROME|FlyBase=FBgn0023489|UniProtKB=Q9XZU0 Q9XZU0 Pph13 PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0284251|UniProtKB=Q9VIG1 Q9VIG1 l(2)05287 PTHR44215:SF1 WD REPEAT-CONTAINING PROTEIN 75 WD REPEAT-CONTAINING PROTEIN 75 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase I#GO:0006356 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 DROME|FlyBase=FBgn0066365|UniProtKB=Q9VZE0 Q9VZE0 dyl PTHR46560:SF2 CYPHER, ISOFORM B DUSKY-LIKE, ISOFORM A developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell morphogenesis#GO:0000902 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 DROME|FlyBase=FBgn0050446|UniProtKB=A1Z6N4 A1Z6N4 Tdc2 PTHR11999:SF70 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE MIP05841P lyase#PC00144;decarboxylase#PC00089 Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961 DROME|FlyBase=FBgn0036487|UniProtKB=Q9VUM1 Q9VUM1 Prp31 PTHR13904:SF0 PRE-MRNA SPLICING FACTOR PRP31 U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0035107|UniProtKB=Q0E8K5 Q0E8K5 mri PTHR21637:SF0 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED AT10158P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0051354|UniProtKB=Q9VG58 Q9VG58 Hsp70Bbb PTHR19375:SF518 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN AA-RELATED protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 DROME|FlyBase=FBgn0031534|UniProtKB=Q9VQQ6 Q9VQQ6 Snx1 PTHR10555:SF170 SORTING NEXIN FI18122P1 binding#GO:0005488;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;retromer complex#GO:0030904;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051533|UniProtKB=Q8ING2 Q8ING2 NEST:bs16a07 PTHR39079:SF1 FI08034P-RELATED GH11706P-RELATED DROME|FlyBase=FBgn0010417|UniProtKB=P49847 P49847 Taf6 PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043 RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP#P00670;General transcription regulation#P00023>TBP-associated factors#P00658 DROME|FlyBase=FBgn0001149|UniProtKB=P20432 P20432 GstD1 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0023167|UniProtKB=O44437 O44437 SmD3 PTHR23338:SF17 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085 U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0035931|UniProtKB=Q9VSQ5 Q9VSQ5 Dmel\CG13312 PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0031245|UniProtKB=Q9VPN0 Q9VPN0 Dmel\CG3625 PTHR10989:SF16 ANDROGEN-INDUCED PROTEIN 1-RELATED AT02829P-RELATED hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 DROME|FlyBase=FBgn0053679|UniProtKB=Q4ABF4 Q4ABF4 Dmel\CG33679 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0264711|UniProtKB=M9PFY3 M9PFY3 CG33291 PTHR46071:SF2 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038957|UniProtKB=Q8T8W6 Q8T8W6 Pgaml PTHR11931:SF11 PHOSPHOGLYCERATE MUTASE BISPHOSPHOGLYCERATE MUTASE isomerase activity#GO:0016853;phosphoglycerate mutase activity#GO:0004619;intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 mutase#PC00160;isomerase#PC00135 Glycolysis#P00024>Phosphoglyceromutase#P00680 DROME|FlyBase=FBgn0038938|UniProtKB=Q9VD40 Q9VD40 Dmel\CG7084 PTHR24064:SF71 SOLUTE CARRIER FAMILY 22 MEMBER RH23644P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0031999|UniProtKB=Q9VLR7 Q9VLR7 Dmel\CG8419 PTHR25462:SF304 BONUS, ISOFORM C-RELATED BONUS, ISOFORM C-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;chromatin binding#GO:0003682;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0035308|UniProtKB=B7Z0I2 B7Z0I2 Dmel\CG15822 PTHR46607:SF1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543 DROME|FlyBase=FBgn0031497|UniProtKB=Q9VQL1 Q9VQL1 SerRS PTHR11778:SF7 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, CYTOPLASMIC tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0036085|UniProtKB=Q9VT97 Q9VT97 BcDNA:AT13283 PTHR10809:SF6 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN AT11025P-RELATED protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0041194|UniProtKB=Q967S0 Q967S0 Prat2 PTHR11907:SF0 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 metabolite interconversion enzyme#PC00262;transferase#PC00220 De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 DROME|FlyBase=FBgn0261560|UniProtKB=Q9XZ56 Q9XZ56 Thor PTHR12669:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN binding#GO:0005488;translation initiation factor binding#GO:0031369;protein binding#GO:0005515;translation regulator activity#GO:0045182 negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605 translation factor#PC00223;translation initiation factor#PC00224 DROME|FlyBase=FBgn0025373|UniProtKB=Q7KN61 Q7KN61 Fpps PTHR11525:SF23 FARNESYL-PYROPHOSPHATE SYNTHETASE FARNESYL PYROPHOSPHATE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;terpenoid metabolic process#GO:0006721;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;terpenoid biosynthetic process#GO:0016114;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 acyltransferase#PC00042;transferase#PC00220 Cholesterol biosynthesis#P00014>Geranyl trans-transferase#P00493 DROME|FlyBase=FBgn0033972|UniProtKB=Q7K1Y4 Q7K1Y4 Ciao1 PTHR19920:SF0 WD40 PROTEIN CIAO1 CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0023527|UniProtKB=Q9W4Z9 Q9W4Z9 Dmel\CG3071 PTHR19924:SF26 UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0028703|UniProtKB=Q8IPJ4 Q8IPJ4 Nhe3 PTHR10110:SF201 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;recycling endosome#GO:0055037 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0030327|UniProtKB=Q9VYV5 Q9VYV5 FucT6 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 DROME|FlyBase=FBgn0053329|UniProtKB=Q7KSK1 Q7KSK1 Sp212 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0053784|UniProtKB=Q4AB35 Q4AB35 HDC12790 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0035266|UniProtKB=Q9W095 Q9W095 Gk2 PTHR10196:SF40 SUGAR KINASE GLYCEROL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;acylglycerol metabolic process#GO:0006639;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;carbohydrate metabolic process#GO:0005975;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 carbohydrate kinase#PC00065;kinase#PC00137 DROME|FlyBase=FBgn0261238|UniProtKB=A0A0B4KGP1 A0A0B4KGP1 Alh PTHR13793:SF164 PHD FINGER PROTEINS ALHAMBRA, ISOFORM P chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0003429|UniProtKB=Q03720 Q03720 slo PTHR10027:SF33 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1A-RELATED metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0260639|UniProtKB=P23257 P23257 gammaTub23C PTHR11588:SF540 TUBULIN TUBULIN GAMMA CHAIN heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;supramolecular fiber organization#GO:0097435;mitotic sister chromatid segregation#GO:0000070;microtubule polymerization or depolymerization#GO:0031109;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule polymerization#GO:0046785;chromosome organization#GO:0051276;microtubule nucleation#GO:0007020;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 tubulin#PC00228;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0032886|UniProtKB=Q9VIJ3 Q9VIJ3 BcDNA:SD01241 PTHR16768:SF5 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A FI14214P DROME|FlyBase=FBgn0039180|UniProtKB=Q9VC98 Q9VC98 Dmel\CG5715 PTHR10127:SF905 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0035909|UniProtKB=Q9V3A8 Q9V3A8 ergic53 PTHR12223:SF28 VESICULAR MANNOSE-BINDING LECTIN LECTIN, MANNOSE BINDING 1 LIKE binding#GO:0005488;small molecule binding#GO:0036094;carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0051140|UniProtKB=A0A0B4KHZ4 A0A0B4KHZ4 Dmel\CG31140 PTHR11255:SF125 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE THETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;primary metabolic process#GO:0044238;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 DROME|FlyBase=FBgn0030351|UniProtKB=Q9VYS6 Q9VYS6 BcDNA:LD12750 PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;calcium ion homeostasis#GO:0055074;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of response to stimulus#GO:0048583;chemical homeostasis#GO:0048878 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 DROME|FlyBase=FBgn0036958|UniProtKB=Q9VWA0 Q9VWA0 Dmel\CG17233 PTHR14689:SF0 PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 82 DROME|FlyBase=FBgn0261618|UniProtKB=Q9VAW5 Q9VAW5 larp PTHR22792:SF101 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0085384|UniProtKB=A0A0B4K709 A0A0B4K709 CG13818 PTHR24036:SF5 SKELETOR-RELATED THROMBOMODULIN transmembrane signal receptor#PC00197 Blood coagulation#P00011>Thrombomodulin#P00457 DROME|FlyBase=FBgn0000116|UniProtKB=P48610 P48610 Argk1 PTHR11547:SF38 ARGININE OR CREATINE KINASE ARGININE KINASE 1-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 DROME|FlyBase=FBgn0261836|UniProtKB=M9MRD1 M9MRD1 Msp300 PTHR47535:SF1 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G MUSCLE-SPECIFIC PROTEIN 300 KDA protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;organelle localization#GO:0051640;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;establishment of localization in cell#GO:0051649;nuclear migration#GO:0007097;cellular process#GO:0009987 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane#GO:0016020;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0027515|UniProtKB=Q9XZ28 Q9XZ28 Dmel\CG7115 PTHR13832:SF827 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1L catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 protein phosphatase#PC00195 DROME|FlyBase=FBgn0026250|UniProtKB=Q9VEA1 Q9VEA1 eIF1A PTHR21668:SF0 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 4C translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0022702|UniProtKB=Q9W092 Q9W092 Cht2 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032525|UniProtKB=Q9VJX7 Q9VJX7 Hsp60D PTHR45633:SF53 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN HOMOLOG 1, MITOCHONDRIAL-RELATED protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;apoptotic process#GO:0006915;cellular component organization#GO:0016043;cellular localization#GO:0051641;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;cell death#GO:0008219;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;protein metabolic process#GO:0019538;localization#GO:0051179;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620 mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0261570|UniProtKB=Q8T498 Q8T498 raskol PTHR10194:SF60 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN RASKOL GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0086909|UniProtKB=Q9VJ68 Q9VJ68 Hykk PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 DROME|FlyBase=FBgn0086710|UniProtKB=Q9VJ19 Q9VJ19 RpL30 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN EL30 structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0270924|UniProtKB=Q9VL91 Q9VL91 zf30C PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0052068|UniProtKB=Q6AWN0 Q6AWN0 Adi1 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0032000|UniProtKB=Q8IPG2 Q8IPG2 Dmel\CG8372 PTHR20921:SF0 TRANSMEMBRANE PROTEIN 222 TRANSMEMBRANE PROTEIN 222 DROME|FlyBase=FBgn0031282|UniProtKB=Q9VPT5 Q9VPT5 Pex12 PTHR12888:SF0 PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12 PEROXISOME ASSEMBLY PROTEIN 12 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 peroxisome organization#GO:0007031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840 microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0051720|UniProtKB=E2QCS3 E2QCS3 mthl15 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0052625|UniProtKB=Q8IR64 Q8IR64 Dmel\CG32625 PTHR21402:SF5 GAMETOCYTE SPECIFIC FACTOR 1-RELATED GAMETOCYTE-SPECIFIC FACTOR 1 DROME|FlyBase=FBgn0263968|UniProtKB=Q70PP2 Q70PP2 nonC PTHR11139:SF119 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE SMG1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;TOR signaling#GO:0031929;signal transduction#GO:0007165;negative regulation of macroautophagy#GO:0016242;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of catabolic process#GO:0009895;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;TOR complex#GO:0038201;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PI3K#P00557 DROME|FlyBase=FBgn0000543|UniProtKB=Q9W032 Q9W032 ecd PTHR13060:SF0 SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2 PROTEIN ECDYSONELESS HOMOLOG transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0036202|UniProtKB=A0A6J3SW69 A0A6J3SW69 loaf PTHR24652:SF71 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 LOST AND FOUND, ISOFORM G DROME|FlyBase=FBgn0036822|UniProtKB=Q9VVT9 Q9VVT9 NijB PTHR12316:SF1 NINJURIN-RELATED NINJURIN-B binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 cell adhesion#GO:0007155;cellular process#GO:0009987;cell death#GO:0008219;programmed cell death#GO:0012501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0032446|UniProtKB=Q9VK67 Q9VK67 IFT43 PTHR33724:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030 membrane-bounded organelle#GO:0043227;intraciliary transport particle A#GO:0030991;intraciliary transport particle#GO:0030990;cilium#GO:0005929;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0030524|UniProtKB=Q9VY84 Q9VY84 Dmel\CG10993 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;protein-containing complex organization#GO:0043933;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0051266|UniProtKB=B7Z0L3 B7Z0L3 CG5240 PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0031653|UniProtKB=Q9VMX9 Q9VMX9 Jon25Biii PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0031281|UniProtKB=Q9VPT4 Q9VPT4 Saf6 PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP#P00670;General transcription regulation#P00023>TBP-associated factors#P00658 DROME|FlyBase=FBgn0000533|UniProtKB=P13582 P13582 ea PTHR24256:SF527 TRYPTASE-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 Toll pathway-drosophila#P06217>EA#P06339 DROME|FlyBase=FBgn0039710|UniProtKB=A0A0B4LHU7 A0A0B4LHU7 dgt1 PTHR13453:SF1 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785 DROME|FlyBase=FBgn0003396|UniProtKB=A1Z8F4 A1Z8F4 shn PTHR45944:SF2 SCHNURRI, ISOFORM F PROTEIN SCHNURRI RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DPP-SCW signaling pathway#P06212>SHN#P06268 DROME|FlyBase=FBgn0017558|UniProtKB=P91622 P91622 Pdk PTHR11947:SF3 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;regulation of biosynthetic process#GO:0009889 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0026418|UniProtKB=M9MSL3 M9MSL3 Hsp110 PTHR45639:SF4 HSC70CB, ISOFORM G-RELATED HSC70CB, ISOFORM G nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072;Hsp70 family chaperone#PC00027 DROME|FlyBase=FBgn0031317|UniProtKB=Q9VPY3 Q9VPY3 Charon PTHR24118:SF99 POTE ANKYRIN DOMAIN CHARON membrane traffic protein#PC00150 DROME|FlyBase=FBgn0031074|UniProtKB=Q9VWC3 Q9VWC3 SkpE PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0261602|UniProtKB=Q9V3G1 Q9V3G1 RpL8 PTHR13691:SF16 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 DROME|FlyBase=FBgn0037815|UniProtKB=Q9VGZ2 Q9VGZ2 Rrp46 PTHR11953:SF1 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP46 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA metabolic process#GO:0016073;nuclear mRNA surveillance#GO:0071028;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;snRNA 3'-end processing#GO:0034472;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 exoribonuclease#PC00099;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0050109|UniProtKB=Q6NLJ9 Q6NLJ9 Triap2 PTHR46403:SF2 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 AT19138P-RELATED lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;intermembrane phospholipid transfer#GO:0120010;phospholipid transport#GO:0015914;membrane organization#GO:0061024;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;cellular process#GO:0009987;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;lipid localization#GO:0010876;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0052105|UniProtKB=Q9VTW5 Q9VTW5 Lmx1a PTHR24208:SF166 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1 ALPHA, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0031935|UniProtKB=Q9VLY5 Q9VLY5 Dmel\CG13793 PTHR11616:SF337 SODIUM/CHLORIDE DEPENDENT TRANSPORTER BLOATED TUBULES, ISOFORM B-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;glycine transmembrane transporter activity#GO:0015187 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;sodium ion transport#GO:0006814;import into cell#GO:0098657;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 DROME|FlyBase=FBgn0021760|UniProtKB=Q9NBD7 Q9NBD7 chb PTHR21567:SF89 CLASP CLIP-ASSOCIATING PROTEIN binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;spindle assembly#GO:0051225;cellular localization#GO:0051641;spindle localization#GO:0051653;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;establishment of localization#GO:0051234;establishment of spindle localization#GO:0051293;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;microtubule#GO:0005874;spindle microtubule#GO:0005876;kinetochore#GO:0000776;cell cortex#GO:0005938;basal part of cell#GO:0045178;chromosome#GO:0005694;cytoplasmic microtubule#GO:0005881;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;spindle#GO:0005819;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0029913|UniProtKB=Q9W3V1 Q9W3V1 Cht11 PTHR11177:SF390 CHITINASE CHITINASE 11 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0250814|UniProtKB=Q9VV75 Q9VV75 UQCR-C2 PTHR11851:SF226 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104 respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;endopeptidase complex#GO:1905369;respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0043865|UniProtKB=Q9W0F4 Q9W0F4 SA2 PTHR11199:SF0 STROMAL ANTIGEN LD34181P-RELATED chromatin binding#GO:0003682;binding#GO:0005488 cell cycle process#GO:0022402;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0085385|UniProtKB=A0A6M3Q8Y2 A0A6M3Q8Y2 bma PTHR12984:SF16 SCY1-RELATED S/T PROTEIN KINASE-LIKE BLACK MATCH, ISOFORM H non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0052133|UniProtKB=Q9VUB7 Q9VUB7 Ptip PTHR23196:SF42 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN PAX-INTERACTING PROTEIN 1 response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0010303|UniProtKB=Q23977 Q23977 hep PTHR47238:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE HEMIPTEROUS non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MKK4,7#P00637;EGF receptor signaling pathway#P00018>MKK4,7#P00555 DROME|FlyBase=FBgn0037992|UniProtKB=A0A0B4K6G0 A0A0B4K6G0 Dmel\CG4702 PTHR41158:SF2 AGAP010294-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0001942|UniProtKB=Q02748 Q02748 eIF4A PTHR24031:SF84 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;cytoplasmic stress granule#GO:0010494;nucleus#GO:0005634;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0086655|UniProtKB=Q7KHG2 Q7KHG2 jing PTHR46541:SF1 ZINC FINGER PROTEIN AEBP2 ZINC FINGER PROTEIN AEBP2 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0259745|UniProtKB=Q9V4M2 Q9V4M2 wech PTHR24104:SF65 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED PROTEIN WECH transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0027329|UniProtKB=Q9VXQ5 Q9VXQ5 CCT6 PTHR11353:SF21 CHAPERONIN CHAPERONIN CONTAINING TCP1 SUBUNIT 6A-RELATED biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperonin#PC00073 DROME|FlyBase=FBgn0053632|UniProtKB=Q0E9B1 Q0E9B1 CR33632 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0032123|UniProtKB=Q9VLB3 Q9VLB3 Oatp30B PTHR11388:SF157 ORGANIC ANION TRANSPORTER ORGANIC ANION TRANSPORTING POLYPEPTIDE 30B, ISOFORM A active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 DROME|FlyBase=FBgn0046225|UniProtKB=Q7K4X4 Q7K4X4 Dmel\CG17230 PTHR31183:SF2 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN programmed cell death#GO:0012501;cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915 intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 structural protein#PC00211 DROME|FlyBase=FBgn0051627|UniProtKB=Q8INU1 Q8INU1 Dmel\CG31627 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0034454|UniProtKB=A1ZBM4 A1ZBM4 Dmel\CG15120 PTHR21207:SF2 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED GH16267P-RELATED heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 DROME|FlyBase=FBgn0053807|UniProtKB=Q4ABD8 Q4ABD8 His1:CG33807 PTHR11467:SF36 HISTONE H1 H1.010 LINKER HISTONE, CLUSTER MEMBER-RELATED DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490 negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;regulation of DNA recombination#GO:0000018 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0037203|UniProtKB=Q9VNP7 Q9VNP7 slif PTHR43243:SF95 INNER MEMBRANE TRANSPORTER YGJI-RELATED LD37241P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0010357|UniProtKB=P35004 P35004 betaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0039522|UniProtKB=Q9VB28 Q9VB28 Dmel\CG13972 PTHR14871:SF2 DYNEIN REGULATORY COMPLEX PROTEIN 9 DYNEIN REGULATORY COMPLEX PROTEIN 9 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782 cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0267348|UniProtKB=P15215 P15215 LanB2 PTHR10574:SF435 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-1 neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;tissue development#GO:0009888;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 DROME|FlyBase=FBgn0024732|UniProtKB=A0A0B4KFQ3 A0A0B4KFQ3 Drep1 PTHR12306:SF15 CELL DEATH ACTIVATOR CIDE DNAATION FACTOR-RELATED PROTEIN 1, ISOFORM B-RELATED programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219 DROME|FlyBase=FBgn0033669|UniProtKB=Q9V637 Q9V637 PI31 PTHR13266:SF1 PROTEASOME INHIBITOR PROTEASOME INHIBITOR PI31 SUBUNIT negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0035009|UniProtKB=Q9W168 Q9W168 Dmel\CG16837 PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0038978|UniProtKB=Q9VCZ5 Q9VCZ5 tHMG1 PTHR48112:SF20 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN D-RELATED chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0033380|UniProtKB=A1Z7P3 A1Z7P3 Phax PTHR13135:SF0 CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26 PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035440|UniProtKB=Q95SH7 Q95SH7 Ostm1 PTHR15644:SF2 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DROME|FlyBase=FBgn0032744|UniProtKB=Q8SYD0 Q8SYD0 Ttc19 PTHR13143:SF6 TETRATRICOPEPTIDE REPEAT PROTEIN 19 TETRATRICOPEPTIDE REPEAT PROTEIN 19, MITOCHONDRIAL cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0052174|UniProtKB=Q9VVG6 Q9VVG6 Coq4 PTHR12922:SF10 UBIQUINONE BIOSYNTHESIS PROTEIN UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0264000|UniProtKB=M9PHV5 M9PHV5 GluRIB PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 DROME|FlyBase=FBgn0001301|UniProtKB=Q04652 Q04652 kel PTHR24412:SF489 KELCH PROTEIN RING CANAL KELCH PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0028864|UniProtKB=Q7KT73 Q7KT73 Dmel\CG18477 PTHR24258:SF129 SERINE PROTEASE-RELATED LP15124P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032488|UniProtKB=Q9VK18 Q9VK18 Dmel\CG16812 PTHR21359:SF1 DUF5577 DOMAIN-CONTAINING PROTEIN DUF5577 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0011016|UniProtKB=Q9VUZ0 Q9VUZ0 SsRbeta PTHR12861:SF3 TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA membrane traffic protein#PC00150 DROME|FlyBase=FBgn0262714|UniProtKB=Q8IQI0 Q8IQI0 Sap130 PTHR13497:SF3 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle lumen#GO:0070013;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0033317|UniProtKB=Q7JWR9 Q7JWR9 CG8635 PTHR12681:SF0 ZINC FINGER-CONTAINING PROTEIN P48ZNF ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0034893|UniProtKB=Q9W1L1 Q9W1L1 mRpL43 PTHR21396:SF2 39S RIBOSOMAL PROTEIN L43 LARGE RIBOSOMAL SUBUNIT PROTEIN ML43 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233 ribosomal protein#PC00202 DROME|FlyBase=FBgn0021767|UniProtKB=Q9W3F4 Q9W3F4 org-1 PTHR11267:SF195 T-BOX PROTEIN-RELATED OPTOMOTOR-BLIND-RELATED-GENE-1, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 DROME|FlyBase=FBgn0039158|UniProtKB=Q9VCC4 Q9VCC4 TBC1d7 PTHR13530:SF3 TBC1 DOMAIN FAMILY MEMBER 7 TBC1 DOMAIN FAMILY MEMBER 7 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;binding#GO:0005488;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TOR signaling#GO:0032006;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0035293|UniProtKB=Q961Q9 Q961Q9 dSLC5A2 PTHR42985:SF39 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH10366P secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 sodium ion transport#GO:0006814;transport#GO:0006810;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0260388|UniProtKB=Q0E8E1 Q0E8E1 AC PTHR23507:SF37 ZGC:174356 GH08173P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039738|UniProtKB=Q961U0 Q961U0 Mgat2 PTHR12871:SF0 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0032609|UniProtKB=Q9VJH7 Q9VJH7 Dmel\CG13280 PTHR22604:SF105 OXIDOREDUCTASES TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0031813|UniProtKB=B7Z028 B7Z028 Acox3 PTHR10909:SF390 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 3 organic acid binding#GO:0043177;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;lipid binding#GO:0008289;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0011020|UniProtKB=Q9VI72 Q9VI72 Sas-4 PTHR10331:SF29 T COMPLEX PROTEIN 10 SPINDLE ASSEMBLY ABNORMAL 4 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cilium assembly#GO:0060271;membraneless organelle assembly#GO:0140694;cell projection organization#GO:0030030;centriole replication#GO:0007099;organelle assembly#GO:0070925;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0013763|UniProtKB=Q23997 Q23997 Idgf6 PTHR11177:SF235 CHITINASE CHITINASE-LIKE PROTEIN IDGF1-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 DROME|FlyBase=FBgn0000120|UniProtKB=P15372 P15372 Arr1 PTHR11792:SF16 ARRESTIN PHOSRESTIN-2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 receptor internalization#GO:0031623;cellular process#GO:0009987;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;vesicle-mediated transport#GO:0016192;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;establishment of localization#GO:0051234;import into cell#GO:0098657;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;nervous system process#GO:0050877;regulation of signaling#GO:0023051;sensory perception#GO:0007600;localization#GO:0051179;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>beta-arrestin#P01456 DROME|FlyBase=FBgn0286834|UniProtKB=A0A4V1D188 A0A4V1D188 Dmel\CG46388 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0031399|UniProtKB=Q9VQ89 Q9VQ89 mio PTHR16453:SF9 WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER GATOR2 COMPLEX PROTEIN MIOS cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;regulation of TORC1 signaling#GO:1903432;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to nutrient levels#GO:0031667;positive regulation of TORC1 signaling#GO:1904263;response to stress#GO:0006950;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0041621|UniProtKB=P82986 P82986 Or82a PTHR21137:SF43 ODORANT RECEPTOR ODORANT RECEPTOR 47A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0011279|UniProtKB=P54191 P54191 Obp69a PTHR11857:SF4 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 69A system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0037252|UniProtKB=Q9VN28 Q9VN28 Dmel\CG14650 PTHR44665:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 14 LD26442P chaperone#PC00072 DROME|FlyBase=FBgn0263605|UniProtKB=M9PFG1 M9PFG1 l(3)72Dn PTHR44163:SF1 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;t-UTP complex#GO:0034455 DROME|FlyBase=FBgn0001992|UniProtKB=Q9V399 Q9V399 Cyp303a1 PTHR24303:SF13 HEME-BINDING MONOOXYGENASE FAMILY CYTOCHROME P450 303A1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0028481|UniProtKB=Q9V3X5 Q9V3X5 Tmtc2 PTHR44216:SF3 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032476|UniProtKB=Q9VK31 Q9VK31 Dmel\CG5439 PTHR47194:SF3 SORTING NEXIN-29-RELATED SORTING NEXIN-29 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038361|UniProtKB=Q9VF38 Q9VF38 Uros2 PTHR12390:SF0 UROPORPHYRINOGEN III SYNTHASE UROPORPHYRINOGEN-III SYNTHASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 porphyrin-containing compound biosynthetic process#GO:0006779;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrapyrrole metabolic process#GO:0033013;small molecule biosynthetic process#GO:0044283;porphyrin-containing compound metabolic process#GO:0006778;small molecule metabolic process#GO:0044281;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Heme biosynthesis#P02746>Uroporphyrinogen-III synthase#P02974 DROME|FlyBase=FBgn0034937|UniProtKB=Q9W1F6 Q9W1F6 fzr2 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;binding#GO:0005488 proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003889|UniProtKB=P61857 P61857 betaTub85D PTHR11588:SF429 TUBULIN TUBULIN BETA 8B-RELATED ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 DROME|FlyBase=FBgn0266446|UniProtKB=C0HK92 C0HK92 CG45076 PTHR23242:SF9 TRANSCRIPTION FACTOR HOXA13 TRANSCRIPTION FACTOR HOXA13 DROME|FlyBase=FBgn0053467|UniProtKB=A0A0B4LFG8 A0A0B4LFG8 Dmel\CG33467 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0037653|UniProtKB=Q9VHI7 Q9VHI7 Iru PTHR15710:SF243 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0036567|UniProtKB=Q9VUY2 Q9VUY2 Dmel\CG13074 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;dynein complex#GO:0030286;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0265185|UniProtKB=C6SV36 C6SV36 CG3884-RB PTHR31649:SF10 AGAP009604-PA IP19903P-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035674|UniProtKB=Q9VRT6 Q9VRT6 Dmel\CG13295 PTHR31596:SF1 T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0033763|UniProtKB=Q8SZ72 Q8SZ72 Dmel\CG8646 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 DROME|FlyBase=FBgn0038725|UniProtKB=A0A0C4FEI3 A0A0C4FEI3 Dmel\CG6184 PTHR21419:SF30 FAMILY NOT NAMED FAM234A_B BETA-PROPELLER DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0023518|UniProtKB=Q8IRW8 Q8IRW8 trr PTHR45888:SF6 HL01030P-RELATED HL01030P-RELATED histone methyltransferase activity#GO:0042054;transcription regulator activity#GO:0140110;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;transcription coactivator activity#GO:0003713;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3 methyltransferase activity#GO:0140938;histone H3K4 methyltransferase activity#GO:0042800;protein methyltransferase activity#GO:0008276;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0003071|UniProtKB=P52034 P52034 Pfk PTHR13697:SF4 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;ADP catabolic process#GO:0046032;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205 intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;carbohydrate kinase#PC00065;kinase#PC00137 Glycolysis#P00024>Phosphofructokinase-1#P00672 DROME|FlyBase=FBgn0035970|UniProtKB=Q9VSV3 Q9VSV3 Dmel\CG4483 PTHR22883:SF23 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0004167|UniProtKB=A8JNJ6 A8JNJ6 kst PTHR11915:SF448 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5 binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0025681|UniProtKB=Q9VQK0 Q9VQK0 CG3558 PTHR21705:SF11 RAI16 PROTEIN-RELATED FHIP FAMILY PROTEIN CG3558 DROME|FlyBase=FBgn0034065|UniProtKB=Q29QQ9 Q29QQ9 Rrp42 PTHR11097:SF8 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP42 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA catabolic process#GO:0006401;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DROME|FlyBase=FBgn0025631|UniProtKB=Q9W534 Q9W534 moody PTHR24228:SF63 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR MOODY molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0054001|UniProtKB=Q2PDX2 Q2PDX2 Dmel\CG34001 PTHR28605:SF1 CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE) CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;positive regulation of DNA metabolic process#GO:0051054;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0037570|UniProtKB=A0A0B4K6X8 A0A0B4K6X8 Dmel\CG11693 PTHR37161:SF3 HDC10475 HDC10475 DROME|FlyBase=FBgn0031436|UniProtKB=Q9VQD7 Q9VQD7 ND-B17.2 PTHR12910:SF2 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0004107|UniProtKB=P23573 P23573 Cdk2 PTHR24056:SF598 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693 response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;signaling#GO:0023052;cell cycle#GO:0007049;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;cell communication#GO:0007154;mitotic cell cycle phase transition#GO:0044772;biological regulation#GO:0065007;signal transduction#GO:0007165;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>cdk2#P04653;p53 pathway#P00059>Cdk2#P04625;p53 pathway#P00059>Cdc2#P04634 DROME|FlyBase=FBgn0039676|UniProtKB=Q9VAJ6 Q9VAJ6 ppk20 PTHR11690:SF299 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 20, ISOFORM A transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0037232|UniProtKB=Q9VN03 Q9VN03 Suv3 PTHR12131:SF31 ATP-DEPENDENT RNA AND DNA HELICASE ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA 3'-end processing#GO:0000965;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 organelle#GO:0043226;mitochondrial protein-containing complex#GO:0098798;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0030035|UniProtKB=Q9W3G0 Q9W3G0 PIG-T PTHR12959:SF11 GPI TRANSAMIDASE COMPONENT PIG-T-RELATED GPI-ANCHOR TRANSAMIDASE COMPONENT PIGT biosynthetic process#GO:0009058;GPI anchored protein biosynthesis#GO:0180046;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0028468|UniProtKB=Q9V395 Q9V395 rtet PTHR23504:SF126 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 BCDNA.LD28419 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0039197|UniProtKB=Q9VC78 Q9VC78 BcDNA:RE41041 PTHR21398:SF23 AGAP007094-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0024360|UniProtKB=O46102 O46102 MTPAP PTHR12271:SF133 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE, MITOCHONDRIAL adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of mRNA metabolic process#GO:1903313;RNA processing#GO:0006396;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 nucleotidyltransferase#PC00174 DROME|FlyBase=FBgn0004103|UniProtKB=P12982 P12982 Pp1-87B PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE-RELATED catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 DROME|FlyBase=FBgn0020257|UniProtKB=A0A0B4KF28 A0A0B4KF28 Ppa PTHR13318:SF190 PARTNER OF PAIRED, ISOFORM B-RELATED PARTNER OF PAIRED, ISOFORM B protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0025525|UniProtKB=Q9W0K4 Q9W0K4 bab2 PTHR23110:SF116 BTB DOMAIN TRANSCRIPTION FACTOR PROTEIN BRIC-A-BRAC 1-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0042133|UniProtKB=Q9I7L7 Q9I7L7 Dmel\CG18810 PTHR22883:SF414 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC24-RELATED palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0026262|UniProtKB=Q9V4D4 Q9V4D4 Taf3 PTHR46452:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 protein binding#GO:0005515;binding#GO:0005488 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0034054|UniProtKB=Q8SXR5 Q8SXR5 Dmel\CG8366 PTHR39953:SF1 RE54151P RE54151P DROME|FlyBase=FBgn0029925|UniProtKB=Q9W3T9 Q9W3T9 Dmel\CG3040 PTHR47186:SF72 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 DROME|FlyBase=FBgn0035264|UniProtKB=Q9W097 Q9W097 Oseg4 PTHR12764:SF5 WD REPEAT DOMAIN-RELATED WD REPEAT-CONTAINING PROTEIN 35 DROME|FlyBase=FBgn0264386|UniProtKB=M9PGH9 M9PGH9 Ca-alpha1T PTHR10037:SF230 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM CA[2+]-CHANNEL PROTEIN ALPHA[[1]] SUBUNIT T, ISOFORM F transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267 calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;biological regulation#GO:0065007;calcium ion import#GO:0070509;action potential#GO:0001508 neuron projection#GO:0043005;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0053640|UniProtKB=Q4ABG1 Q4ABG1 Dmel\CG33640 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0065108|UniProtKB=Q86LG7 Q86LG7 ppk16 PTHR11690:SF237 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 27-RELATED passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0011661|UniProtKB=P46150 P46150 Moe PTHR23281:SF18 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of anatomical structure morphogenesis#GO:0022603;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008 adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;filopodium#GO:0030175;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0035689|UniProtKB=Q9VRV2 Q9VRV2 Dmel\CG7376 PTHR45865:SF2 E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE SHPRH transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0030304|UniProtKB=Q9VYY4 Q9VYY4 Cyp4g15 PTHR24291:SF106 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4G1-RELATED oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0264087|UniProtKB=Q8IPH9 Q8IPH9 Slob PTHR22999:SF31 PX SERINE/THREONINE KINASE PXK SLOWPOKE-BINDING PROTEIN protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 DROME|FlyBase=FBgn0037918|UniProtKB=Q8T007 Q8T007 Dmel\CG6791 PTHR24409:SF413 ZINC FINGER PROTEIN 142 DATILOGRAFO, ISOFORM A-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0033179|UniProtKB=Q7K3Z3 Q7K3Z3 p47 PTHR23333:SF20 UBX DOMAIN CONTAINING PROTEIN GH01724P protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular localization#GO:0051641;spindle localization#GO:0051653;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment or maintenance of cell polarity#GO:0007163;cytoskeleton organization#GO:0007010;proteasomal protein catabolic process#GO:0010498;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;modification-dependent protein catabolic process#GO:0019941;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;primary metabolic process#GO:0044238;microtubule cytoskeleton organization involved in mitosis#GO:1902850;localization#GO:0051179;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;organelle localization#GO:0051640;establishment of spindle localization#GO:0051293;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0039451|UniProtKB=Q9VBC4 Q9VBC4 Wdr20 PTHR14107:SF24 WD REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 20 HOMOLOG enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504 regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DROME|FlyBase=FBgn0016078|UniProtKB=Q9V576 Q9V576 wun PTHR10165:SF103 LIPID PHOSPHATE PHOSPHATASE FI04477P-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;dephosphorylation#GO:0016311;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0032785|UniProtKB=Q8T9G7 Q8T9G7 mcw PTHR10174:SF234 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED SD01558P ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0031773|UniProtKB=Q9VMI1 Q9VMI1 Fbw5 PTHR20995:SF17 F-BOX/WD REPEAT-CONTAINING PROTEIN 5 F-BOX_WD REPEAT-CONTAINING PROTEIN 5 DROME|FlyBase=FBgn0053302|UniProtKB=Q8IPD5 Q8IPD5 Cpr31A PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039530|UniProtKB=A0A0B4KI44 A0A0B4KI44 Tusp PTHR16517:SF2 TUBBY-RELATED TUBBY-RELATED PROTEIN 4 macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035063|UniProtKB=Q9W108 Q9W108 Dmel\CG3594 PTHR23236:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H RNA-BINDING PROTEIN 34 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 DROME|FlyBase=FBgn0027527|UniProtKB=Q9XZ15 Q9XZ15 Osi6 PTHR21879:SF18 FI03362P-RELATED-RELATED LD17368P cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0031257|UniProtKB=Q9VPQ3 Q9VPQ3 Dmel\CG4133 PTHR21385:SF0 ZINC FINGER PROTEIN-RELATED RE51073P DROME|FlyBase=FBgn0036083|UniProtKB=Q9VT95 Q9VT95 Ir67b PTHR42643:SF39 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 56A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0038719|UniProtKB=Q9VDV6 Q9VDV6 Dmel\CG16727 PTHR24064:SF467 SOLUTE CARRIER FAMILY 22 MEMBER FI01439P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0027378|UniProtKB=Q9Y0I1 Q9Y0I1 MRG15 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0005590|UniProtKB=P54631 P54631 scw PTHR11848:SF310 TGF-BETA FAMILY PROTEIN 60A-RELATED molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 DPP-SCW signaling pathway#P06212>SCW full length#P06275;SCW signaling pathway#P06216>SCW#P06326;DPP-SCW signaling pathway#P06212>SCW#P06259;TGF-beta signaling pathway#P00052>TGFbeta#P01286;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;SCW signaling pathway#P06216>SCW full length#P06322;GBB signaling pathway#P06214>GBB#P06294;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256 DROME|FlyBase=FBgn0037837|UniProtKB=A0A0B4KGS5 A0A0B4KGS5 Dmel\CG14693 PTHR23011:SF41 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4-LIKE DROME|FlyBase=FBgn0026616|UniProtKB=Q9VF33 Q9VF33 alpha-Man-IIb PTHR11607:SF70 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121;glycosidase#PC00110 DROME|FlyBase=FBgn0036913|UniProtKB=M9PD06 M9PD06 Usp32 PTHR21646:SF76 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;positive regulation of TORC1 signaling#GO:1904263;positive regulation of cellular process#GO:0048522;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of biological quality#GO:0065008;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081 DROME|FlyBase=FBgn0026620|UniProtKB=A0A0B4JD97 A0A0B4JD97 tacc PTHR13924:SF13 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL PROTEIN, ISOFORM K transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;organelle localization#GO:0051640;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;cell cycle process#GO:0022402;nuclear migration#GO:0007097;cellular component organization#GO:0016043;cell cycle#GO:0007049;establishment of organelle localization#GO:0051656;cytoplasmic microtubule organization#GO:0031122 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0065109|UniProtKB=Q9VL84 Q9VL84 ppk11 PTHR11690:SF237 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 27-RELATED ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0036228|UniProtKB=Q9VTR3 Q9VTR3 obst-G PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED carbohydrate derivative binding#GO:0097367;binding#GO:0005488 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 DROME|FlyBase=FBgn0032779|UniProtKB=Q9VIW9 Q9VIW9 Alp12 PTHR11596:SF91 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0031490|UniProtKB=Q9VQK3 Q9VQK3 Dmel\CG17264 PTHR33236:SF4 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0004926|UniProtKB=P41375 P41375 eIF2beta PTHR23001:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 translation initiation factor binding#GO:0031369;translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051;RNA binding#GO:0003723;protein binding#GO:0005515;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 DROME|FlyBase=FBgn0267435|UniProtKB=P12024 P12024 chp PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0264075|UniProtKB=O15945 O15945 tgo PTHR23042:SF76 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR HOMOLOG sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0004242|UniProtKB=P21521 P21521 Syt1 PTHR10024:SF227 SYNAPTOTAGMIN SYNAPTOTAGMIN 1 SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299 regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;synaptic signaling#GO:0099536;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;regulation of neurotransmitter transport#GO:0051588;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;export from cell#GO:0140352;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;regulation of exocytosis#GO:0017157;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646 presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;organelle membrane#GO:0031090;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 DROME|FlyBase=FBgn0001983|UniProtKB=Q9VJP2 Q9VJP2 wor PTHR24409:SF455 ZINC FINGER PROTEIN 142 WORNIU transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0086519|UniProtKB=Q7JZV0 Q7JZV0 Cpr47Eg PTHR10380:SF242 CUTICLE PROTEIN CUTICULAR PROTEIN 47EG-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0050122|UniProtKB=E1JGL8 E1JGL8 Dmel\CG30122 PTHR12381:SF56 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0025692|UniProtKB=Q8T8W2 Q8T8W2 Lfg PTHR23291:SF131 BAX INHIBITOR-RELATED TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0263830|UniProtKB=Q5LJT3 Q5LJT3 CG12466 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0051002|UniProtKB=Q9V9X9 Q9V9X9 Ugt35D1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 DROME|FlyBase=FBgn0030952|UniProtKB=Q9VWR0 Q9VWR0 Dmel\CG12609 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0015008|UniProtKB=Q9VEQ5 Q9VEQ5 Actn3 PTHR23167:SF96 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED ALPHA ACTININ 3-RELATED cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037756|UniProtKB=Q9VH64 Q9VH64 Dmel\CG8507 PTHR16560:SF3 ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN LD29322P regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100;biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0032652|UniProtKB=Q9VJC0 Q9VJC0 Dmel\CG6870 PTHR19359:SF164 CYTOCHROME B5 CYTOCHROME B5 TYPE B tetrapyrrole binding#GO:0046906;binding#GO:0005488;heme binding#GO:0020037 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane#GO:0016020 oxidoreductase#PC00176 DROME|FlyBase=FBgn0029935|UniProtKB=Q9W3S5 Q9W3S5 Dmel\CG4615 PTHR20855:SF3 ADIPOR/PROGESTIN RECEPTOR-RELATED LD03007P G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0032054|UniProtKB=Q9VLJ8 Q9VLJ8 Mocs3 PTHR10953:SF254 UBIQUITIN-ACTIVATING ENZYME E1 ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;protein modification by small protein conjugation or removal#GO:0070647;tRNA thio-modification#GO:0034227;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;tRNA wobble position uridine thiolation#GO:0002143;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030833|UniProtKB=Q9VX63 Q9VX63 Dmel\CG8915 PTHR18934:SF213 ATP-DEPENDENT RNA HELICASE 3'-5' RNA HELICASE YTHDC2 helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0052150|UniProtKB=Q9VUU9 Q9VUU9 meru PTHR15286:SF15 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN MERU, ISOFORM A scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0050008|UniProtKB=Q8SXD1 Q8SXD1 CG12138 PTHR11157:SF164 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0035300|UniProtKB=Q9W056 Q9W056 acs PTHR22950:SF340 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0038221|UniProtKB=Q9VFL0 Q9VFL0 IFT54 PTHR31363:SF0 TRAF3-INTERACTING PROTEIN 1 TRAF3-INTERACTING PROTEIN 1 microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;intraciliary transport#GO:0042073;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705 microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0037896|UniProtKB=Q9VGP2 Q9VGP2 ninaG PTHR11552:SF188 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE NEITHER INACTIVATION NOR AFTERPOTENTIAL PROTEIN G oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0264962|UniProtKB=A1Z9W4 A1Z9W4 Pcf11 PTHR15921:SF3 PRE-MRNA CLEAVAGE COMPLEX II PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11 RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA binding#GO:0003723;enzyme binding#GO:0019899;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase binding#GO:0070063 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;macromolecule metabolic process#GO:0043170;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0260431|UniProtKB=E1JI94 E1JI94 Dmel\CG42526 PTHR12243:SF67 MADF DOMAIN TRANSCRIPTION FACTOR COREPRESSOR OF PANGOLIN, ISOFORM A-RELATED regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0260467|UniProtKB=Q8SXS0 Q8SXS0 Dmel\CG7071 PTHR31394:SF1 TRANSMEMBRANE PROTEIN 199 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA12 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0261524|UniProtKB=O62602 O62602 lic PTHR48013:SF11 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MKK3,6#P00625;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Huntington disease#P00029>SEK-1#P00792 DROME|FlyBase=FBgn0036830|UniProtKB=Q9VVU8 Q9VVU8 COX6AL2 PTHR11504:SF17 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidase#PC00175 DROME|FlyBase=FBgn0026441|UniProtKB=A0A0B4KG69 A0A0B4KG69 ear PTHR23195:SF27 YEATS DOMAIN ENL_AF9-RELATED, ISOFORM B histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493 general transcription factor#PC00259 DROME|FlyBase=FBgn0023520|UniProtKB=O46080 O46080 CG3857 PTHR14270:SF0 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 DROME|FlyBase=FBgn0038960|UniProtKB=Q9VD15 Q9VD15 Dmel\CG13855 PTHR21074:SF0 IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN IQ MOTIF AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;endomembrane system#GO:0012505;secretory vesicle#GO:0099503;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cilium#GO:0005929;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669 DROME|FlyBase=FBgn0033999|UniProtKB=Q4V6L4 Q4V6L4 vaha PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0052792|UniProtKB=Q0KHW3 Q0KHW3 ppk8 PTHR11690:SF243 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 12-RELATED ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0004407|UniProtKB=Q9VJV8 Q9VJV8 PolG2 PTHR10745:SF8 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 DNA POLYMERASE SUBUNIT GAMMA-2 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;catalytic activity, acting on a tRNA#GO:0140101;molecular function regulator activity#GO:0098772;catalytic activity, acting on RNA#GO:0140098;enzyme activator activity#GO:0008047;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 tRNA metabolic process#GO:0006399;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial DNA metabolic process#GO:0032042;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;protein biosynthetic process#GO:0160307 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0010225|UniProtKB=Q07171 Q07171 Gel PTHR11977:SF123 VILLIN GELSOLIN phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;actin filament binding#GO:0051015;actin binding#GO:0003779;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;regulation of actin filament depolymerization#GO:0030834;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 FAS signaling pathway#P00020>Gelsolin#P00611 DROME|FlyBase=FBgn0050181|UniProtKB=Q8MLR6 Q8MLR6 ppk3 PTHR11690:SF285 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0039876|UniProtKB=A0A0B4KHY1 A0A0B4KHY1 anon-WO0118547.412 PTHR12740:SF4 JNK1/MAPK8-ASSOCIATED MEMBRANE PROTEIN JNK1_MAPK8-ASSOCIATED MEMBRANE PROTEIN ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0041184|UniProtKB=Q8INY1 Q8INY1 Socs36E PTHR10155:SF38 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING AT 36E, ISOFORM D biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 DROME|FlyBase=FBgn0032921|UniProtKB=Q95PE4 Q95PE4 Mpp6 PTHR13582:SF0 M-PHASE PHOSPHOPROTEIN 6 M-PHASE PHOSPHOPROTEIN 6 ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0020513|UniProtKB=Q9I7S8 Q9I7S8 Paics PTHR43599:SF3 MULTIFUNCTIONAL PROTEIN ADE2 BIFUNCTIONAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE_PHOSPHORIBOSYLAMINOIMIDAZOLE SUCCINOCARBOXAMIDE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0041249|UniProtKB=P58954 P58954 Gr22f PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0032130|UniProtKB=Q9VLA6 Q9VLA6 brwl PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0045852|UniProtKB=Q8I7Z8 Q8I7Z8 ham PTHR24393:SF183 ZINC FINGER PROTEIN LD28458P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0034455|UniProtKB=Q7JW12 Q7JW12 CG11007 PTHR15853:SF1 THIOREDOXIN-RELATED THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2 HOMOLOG oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle membrane contact site#GO:0044232;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasm#GO:0005737;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0027546|UniProtKB=Q9Y106 Q9Y106 CG4766 PTHR10656:SF70 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE transferase#PC00220;nucleotidyltransferase#PC00174 DROME|FlyBase=FBgn0035475|UniProtKB=Q9VZK9 Q9VZK9 Dmel\CG10866 PTHR13628:SF1 TRANSMEMBRANE PROTEIN 267 TRANSMEMBRANE PROTEIN 267 DROME|FlyBase=FBgn0033404|UniProtKB=Q9V568 Q9V568 Or45a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038113|UniProtKB=Q8MS90 Q8MS90 SP115 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0034362|UniProtKB=Q7JVK8 Q7JVK8 Dmel\CG5323 PTHR21096:SF0 PROTEIN FAM136A TIM DOUBLE TWIN CX3C MOTIF PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0267795|UniProtKB=Q9VUC6 Q9VUC6 Frl PTHR45857:SF10 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DROME|FlyBase=FBgn0000092|UniProtKB=O76879 O76879 dyw PTHR11008:SF42 PROTEIN TAKEOUT-LIKE PROTEIN CIRCADIAN CLOCK-CONTROLLED PROTEIN DAYWAKE-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0031818|UniProtKB=Q9VMD2 Q9VMD2 Dmel\CG9536 PTHR13377:SF3 PLACENTAL PROTEIN 6 TRANSMEMBRANE PROTEIN 115 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;organelle#GO:0043226 membrane traffic protein#PC00150;vesicle coat protein#PC00235 DROME|FlyBase=FBgn0031267|UniProtKB=Q9VPR6 Q9VPR6 Ipk2 PTHR12400:SF51 INOSITOL POLYPHOSPHATE KINASE INOSITOL POLYPHOSPHATE MULTIKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 kinase#PC00137 DROME|FlyBase=FBgn0050287|UniProtKB=Q8MLV8 Q8MLV8 SPH37 PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0030528|UniProtKB=Q9VY79 Q9VY79 Dmel\CG11095 PTHR12992:SF11 NUDIX HYDROLASE MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 organophosphate catabolic process#GO:0046434;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound catabolic process#GO:0044273;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0045487|UniProtKB=P58955 P58955 Gr36a PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031038|UniProtKB=Q8IQW4 Q8IQW4 Tyler PTHR45760:SF2 FI19922P1-RELATED FI19922P1-RELATED cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0010412|UniProtKB=P39018 P39018 RpS19a PTHR11710:SF0 40S RIBOSOMAL PROTEIN S19 SMALL RIBOSOMAL SUBUNIT PROTEIN ES19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 DROME|FlyBase=FBgn0035042|UniProtKB=Q9W129 Q9W129 Dmel\CG3640 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0029812|UniProtKB=Q9W470 Q9W470 Prosbeta2R1 PTHR11599:SF44 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0032221|UniProtKB=A8DYY6 A8DYY6 Schip1 PTHR13103:SF2 SCHWANNOMIN INTERACTING PROTEIN 1 IQCJ-SCHIP1 READTHROUGH TRANSCRIPT PROTEIN-RELATED positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0036789|UniProtKB=A0A0S0WMT8 A0A0S0WMT8 AstC-R2 PTHR24229:SF114 NEUROPEPTIDES RECEPTOR ALLATOSTATIN C RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;binding#GO:0005488 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 DROME|FlyBase=FBgn0050089|UniProtKB=A1ZA45 A1ZA45 CG12967 PTHR37002:SF10 AGAP007005-PA F-BOX_LRR-REPEAT PROTEIN 15-LIKE LEUCIN RICH REPEAT DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0028645|UniProtKB=Q9VJM9 Q9VJM9 beat-Ib PTHR21261:SF8 BEAT PROTEIN BEATEN PATH IA, ISOFORM B-RELATED animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0260965|UniProtKB=Q9VU16 Q9VU16 CG11008 PTHR15052:SF2 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;rDNA binding#GO:0000182;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676 DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA transcription#GO:0009303;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription factor TFIIIC complex#GO:0000127;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0020637|UniProtKB=C0HL65 C0HL65 Lcp65Ag2 PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0033081|UniProtKB=Q7JX41 Q7JX41 geminin PTHR13372:SF5 GEMININ GEMININ transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA replication#GO:0006275;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated DNA replication initiation#GO:0030174;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033274|UniProtKB=Q4V5I9 Q4V5I9 CG14757 PTHR12469:SF2 PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex II assembly#GO:0034553;electron transport chain#GO:0022900;tricarboxylic acid cycle#GO:0006099;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039590|UniProtKB=Q9VAU5 Q9VAU5 Dmel\CG10011 PTHR24123:SF65 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50 intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0053180|UniProtKB=Q9GQN0 Q9GQN0 Ranbp16 PTHR12596:SF2 EXPORTIN 4,7-RELATED EXPORTIN-7 ISOFORM X1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 transporter#PC00227 DROME|FlyBase=FBgn0038840|UniProtKB=A0A0B4KHJ0 A0A0B4KHJ0 Grik PTHR18966:SF349 IONOTROPIC GLUTAMATE RECEPTOR FI04462P-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0032031|UniProtKB=Q9VLN0 Q9VLN0 Dmel\CG13390 PTHR11702:SF31 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0024846|UniProtKB=O61443 O61443 p38b PTHR24055:SF615 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE P38A-RELATED catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;FGF signaling pathway#P00021>p38#P00644;TGF-beta signaling pathway#P00052>P38#P01275;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Parkinson disease#P00049>p38 MAPK#P01212 DROME|FlyBase=FBgn0029837|UniProtKB=M9PDV2 M9PDV2 Tsp5D PTHR19282:SF478 TETRASPANIN TETRASPANIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0262579|UniProtKB=Q6IDD9 Q6IDD9 Sarm PTHR22998:SF1 SARM1 NAD(+) HYDROLASE SARM1 catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;cell body#GO:0044297;mitochondrion#GO:0005739;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0250785|UniProtKB=Q7KT16 Q7KT16 vari PTHR23122:SF69 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK FI17352P1 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037022|UniProtKB=Q9VPB6 Q9VPB6 Dmel\CG11396 PTHR21581:SF34 D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226 protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0036932|UniProtKB=Q9VW73 Q9VW73 Lamtor1 PTHR13401:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to acid chemical#GO:0001101;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;membrane#GO:0016020 DROME|FlyBase=FBgn0031090|UniProtKB=Q9W5X0 Q9W5X0 Rab35 PTHR47977:SF128 RAS-RELATED PROTEIN RAB LD21953P ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787 localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 small GTPase#PC00208 DROME|FlyBase=FBgn0038307|UniProtKB=Q9VFB2 Q9VFB2 mRpS10 PTHR13334:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN US10M mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0262559|UniProtKB=Q9VEB1 Q9VEB1 Mdh2 PTHR11540:SF76 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 DROME|FlyBase=FBgn0035785|UniProtKB=Q9VS73 Q9VS73 ppk26 PTHR11690:SF288 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0037834|UniProtKB=Q9VGW7 Q9VGW7 Art1 PTHR11006:SF124 PROTEIN ARGININE N-METHYLTRANSFERASE ARGININE METHYLTRANSFERASE 9-RELATED histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone modifying activity#GO:0140993;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0262636|UniProtKB=Q7KQN5 Q7KQN5 dati PTHR24409:SF413 ZINC FINGER PROTEIN 142 DATILOGRAFO, ISOFORM A-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0030001|UniProtKB=Q9W3K2 Q9W3K2 cyr PTHR46560:SF15 CYPHER, ISOFORM B CYPHER, ISOFORM B anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856;cell morphogenesis#GO:0000902 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 DROME|FlyBase=FBgn0015553|UniProtKB=Q24558 Q24558 tos PTHR11081:SF8 FLAP ENDONUCLEASE FAMILY MEMBER EXONUCLEASE 1 endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0026192|UniProtKB=O97111 O97111 par-6 PTHR14102:SF11 PAR-6-RELATED LD29223P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217;microtubule cytoskeleton organization#GO:0000226;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;establishment or maintenance of cell polarity#GO:0007163;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell cortex#GO:0005938;cell periphery#GO:0071944;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234 cell junction protein#PC00070;tight junction#PC00214 DROME|FlyBase=FBgn0037345|UniProtKB=Q9VNE1 Q9VNE1 PolZ2 PTHR11842:SF10 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;DNA polymerase complex#GO:0042575;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0031801|UniProtKB=Q9VMF0 Q9VMF0 Dmel\CG9498 PTHR11012:SF56 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0000078|UniProtKB=P81641 P81641 Amy-d PTHR43447:SF61 ALPHA-AMYLASE ALPHA-AMYLASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 amylase#PC00048 DROME|FlyBase=FBgn0003210|UniProtKB=Q9W4K1 Q9W4K1 rb PTHR11134:SF34 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;lysosome organization#GO:0007040;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;vacuole organization#GO:0007033;cellular component organization#GO:0016043 membrane protein complex#GO:0098796;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;coated membrane#GO:0048475;membrane coat#GO:0030117;AP-type membrane coat adaptor complex#GO:0030119;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0036666|UniProtKB=Q9VVA7 Q9VVA7 TSG101 PTHR23306:SF3 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED TUMOR SUPPRESSOR PROTEIN 101 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;ESCRT I complex#GO:0000813;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0033271|UniProtKB=Q7JRF9 Q7JRF9 Dmel\CG8708 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 transferase#PC00220 DROME|FlyBase=FBgn0003483|UniProtKB=Q9VF26 Q9VF26 spn-E PTHR18934:SF113 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE TDRD9 isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035402|UniProtKB=Q9VZU7 Q9VZU7 Usp5 PTHR24006:SF664 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 DROME|FlyBase=FBgn0013773|UniProtKB=Q9V769 Q9V769 Cyp6a22 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0031331|UniProtKB=Q9VQ00 Q9VQ00 Dmel\CG5440 PTHR24068:SF291 UBIQUITIN-CONJUGATING ENZYME E2 AT30415P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0032082|UniProtKB=Q9VLG3 Q9VLG3 gi21430616 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0039042|UniProtKB=Q9VCS0 Q9VCS0 Dmel\CG13837 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0037539|UniProtKB=Q9VHX1 Q9VHX1 Dmel\CG10435 PTHR15960:SF5 LD44032P LD44032P binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 vesicle membrane#GO:0012506;ESCRT I complex#GO:0000813;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0045073|UniProtKB=P83094 P83094 Stim PTHR15136:SF5 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE HOMOLOG binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transporter regulator activity#GO:0141108;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;channel regulator activity#GO:0016247;cation binding#GO:0043169;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;molecular function regulator activity#GO:0098772 monoatomic ion homeostasis#GO:0050801;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 DROME|FlyBase=FBgn0053460|UniProtKB=Q4V532 Q4V532 CG30086 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0261383|UniProtKB=Q9W485 Q9W485 IntS6 PTHR12957:SF2 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA helicase#PC00032 DROME|FlyBase=FBgn0043005|UniProtKB=Q9VCJ5 Q9VCJ5 prt PTHR23506:SF4 GH10249P PORTABELLA monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;solute:sodium symporter activity#GO:0015370;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504 establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705 axon terminus#GO:0043679;organelle membrane#GO:0031090;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;distal axon#GO:0150034;intracellular membrane-bounded organelle#GO:0043231;neuron projection terminus#GO:0044306;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular vesicle#GO:0097708 secondary carrier transporter#PC00258;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089 DROME|FlyBase=FBgn0023542|UniProtKB=O46050 O46050 Nmd3 PTHR12746:SF2 NONSENSE-MEDIATED MRNA DECAY PROTEIN 3 60S RIBOSOMAL EXPORT PROTEIN NMD3 binding#GO:0005488;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0027553|UniProtKB=Q9Y113 Q9Y113 NELF-B PTHR13503:SF3 NEGATIVE ELONGATION FACTOR COMPLEX MEMBER B NEGATIVE ELONGATION FACTOR B regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;stem cell differentiation#GO:0048863;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0037993|UniProtKB=Q9VGD0 Q9VGD0 dpr15 PTHR23279:SF21 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 11, ISOFORM B-RELATED cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253 DROME|FlyBase=FBgn0037794|UniProtKB=Q9VH18 Q9VH18 Dmel\CG6254 PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0001200|UniProtKB=P84040 P84040 His4 PTHR10484:SF162 HISTONE H4 HISTONE H4-LIKE PROTEIN TYPE G structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0262595|UniProtKB=A1ZBB5 A1ZBB5 CheA56a PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0035928|UniProtKB=Q9VSQ2 Q9VSQ2 Dmel\CG13310 PTHR33236:SF5 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0037489|UniProtKB=Q9VI82 Q9VI82 Noc3 PTHR14428:SF5 NUCLEOLAR COMPLEX PROTEIN 3 NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488 cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DROME|FlyBase=FBgn0002906|UniProtKB=Q9VGI8 Q9VGI8 Blm PTHR13710:SF153 DNA HELICASE RECQ FAMILY MEMBER RECQ-LIKE DNA HELICASE BLM macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009;DNA helicase#PC00011 DROME|FlyBase=FBgn0031107|UniProtKB=Q9VR91 Q9VR91 HERC2 PTHR22870:SF398 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0031882|UniProtKB=Q9VM50 Q9VM50 Rab30 PTHR47977:SF64 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-30 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport#GO:0006810 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;organelle#GO:0043226;Golgi cisterna#GO:0031985;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 small GTPase#PC00208 DROME|FlyBase=FBgn0015575|UniProtKB=Q9VIB5 Q9VIB5 alpha-Est7 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0051739|UniProtKB=M9PDL2 M9PDL2 AspRS-m PTHR22594:SF56 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0032981|UniProtKB=Q9V9N3 Q9V9N3 Dmel\CG3635 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0031910|UniProtKB=Q9VM16 Q9VM16 Dmel\CG15818 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN binding#GO:0005488;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0262116|UniProtKB=Q8MSF5 Q8MSF5 RNASEK PTHR31733:SF1 RIBONUCLEASE KAPPA RIBONUCLEASE KAPPA cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737 endoribonuclease#PC00094 DROME|FlyBase=FBgn0030343|UniProtKB=Q9VYT4 Q9VYT4 ATP7 PTHR43520:SF35 ATP7, ISOFORM B P-TYPE CU(+) TRANSPORTER ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;binding#GO:0005488;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;transporter activity#GO:0005215;copper ion binding#GO:0005507;metal ion transmembrane transporter activity#GO:0046873;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;copper ion transmembrane transport#GO:0035434;metal ion transport#GO:0030001;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020 primary active transporter#PC00068 DROME|FlyBase=FBgn0032717|UniProtKB=B7YZX6 B7YZX6 Dmel\CG10600 PTHR13354:SF12 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE 9 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;protein demethylase activity#GO:0140457;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0024320|UniProtKB=Q9VL24 Q9VL24 Npc1a PTHR45727:SF11 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 transport#GO:0006810;chemical homeostasis#GO:0048878;lipid localization#GO:0010876;system process#GO:0003008;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;establishment of localization#GO:0051234;sterol transport#GO:0015918;cholesterol homeostasis#GO:0042632;macromolecule localization#GO:0033036;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;lipid transport#GO:0006869;digestion#GO:0007586;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0003890|UniProtKB=Q8MST5 Q8MST5 betaTub97EF PTHR11588:SF490 TUBULIN TUBULIN BETA CHAIN structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;tubulin#PC00228 DROME|FlyBase=FBgn0050469|UniProtKB=A1ZA15 A1ZA15 Ir52b PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0013813|UniProtKB=Q9VAV5 Q9VAV5 Dhc98D PTHR10676:SF343 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 10 microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824 cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;microtubule-based movement#GO:0007018;cell motility#GO:0048870 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;dynein complex#GO:0030286;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0035144|UniProtKB=Q9W0P9 Q9W0P9 Kah PTHR24388:SF118 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 507 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0284249|UniProtKB=P05552 P05552 Adf1 PTHR12243:SF67 MADF DOMAIN TRANSCRIPTION FACTOR COREPRESSOR OF PANGOLIN, ISOFORM A-RELATED regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0033865|UniProtKB=A1Z9G9 A1Z9G9 Cdc73L PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591 DROME|FlyBase=FBgn0037416|UniProtKB=Q9VNM9 Q9VNM9 Osi9 PTHR21879:SF1 FI03362P-RELATED-RELATED FI01546P cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0036908|UniProtKB=Q9VW40 Q9VW40 TORIP PTHR18843:SF7 TORSIN-1A-INTERACTING PROTEIN SI:DKEYP-82A1.6 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0003656|UniProtKB=Q9U969 Q9U969 sws PTHR14226:SF29 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER NEUROPATHY TARGET ESTERASE SWS hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 esterase#PC00097;hydrolase#PC00121 DROME|FlyBase=FBgn0039003|UniProtKB=Q8IMZ9 Q8IMZ9 wfs1 PTHR13098:SF3 WOLFRAMIN WOLFRAMIN cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;homeostatic process#GO:0042592;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;inorganic ion homeostasis#GO:0098771;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;calcium ion homeostasis#GO:0055074;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 DROME|FlyBase=FBgn0038701|UniProtKB=Q9VDX6 Q9VDX6 Dmel\CG18493 PTHR11010:SF5 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED RE36938P-RELATED serine protease#PC00203 DROME|FlyBase=FBgn0035886|UniProtKB=Q9VSJ1 Q9VSJ1 Jon66Ci PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0039767|UniProtKB=Q9VA79 Q9VA79 UIP5 PTHR13492:SF2 RING FINGER PROTEIN 37 RING FINGER PROTEIN 37 ubiquitin-like protein ligase binding#GO:0044389;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin protein ligase binding#GO:0031625;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0259991|UniProtKB=E1JIX4 E1JIX4 Dmel\CG42488 PTHR47229:SF1 TRANSMEMBRANE PROTEIN 141 TRANSMEMBRANE PROTEIN 141 DROME|FlyBase=FBgn0011742|UniProtKB=P45888 P45888 Arp2 PTHR11937:SF37 ACTIN ACTIN-RELATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 organelle organization#GO:0006996;cellular component organization#GO:0016043;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807 DROME|FlyBase=FBgn0015791|UniProtKB=Q86BK8 Q86BK8 Rab14 PTHR24073:SF185 DRAB5-RELATED RAS-RELATED PROTEIN RAB-14 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 Golgi to endosome transport#GO:0006895;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;endocytosis#GO:0006897;organelle assembly#GO:0070925;post-Golgi vesicle-mediated transport#GO:0006892;vacuole organization#GO:0007033;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;lytic vacuole organization#GO:0080171;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;phagocytic vesicle#GO:0045335;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 small GTPase#PC00208;G-protein#PC00020 DROME|FlyBase=FBgn0285952|UniProtKB=Q9GU68 Q9GU68 eEF5 PTHR11673:SF6 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0013772|UniProtKB=Q27593 Q27593 Cyp6a8 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0039485|UniProtKB=Q9VB77 Q9VB77 Jhbp11 PTHR11008:SF25 PROTEIN TAKEOUT-LIKE PROTEIN IP09473P-RELATED rhythmic process#GO:0048511;circadian rhythm#GO:0007623 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039132|UniProtKB=B8A403 B8A403 AP-1sigma PTHR11753:SF5 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP COMPLEX SUBUNIT SIGMA vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;vesicle coat protein#PC00235 DROME|FlyBase=FBgn0028866|UniProtKB=Q7KT83 Q7KT83 DS06874.6 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0030645|UniProtKB=Q9VXU7 Q9VXU7 Alg14 PTHR12154:SF4 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 transferase#PC00220 DROME|FlyBase=FBgn0039869|UniProtKB=Q9V9U7 Q9V9U7 Tbca PTHR21500:SF0 TUBULIN-SPECIFIC CHAPERONE A TUBULIN-SPECIFIC CHAPERONE A tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chaperonin#PC00073 DROME|FlyBase=FBgn0004855|UniProtKB=P36958 P36958 Polr2I PTHR11239:SF1 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;DNA-templated transcription elongation#GO:0006354;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 DROME|FlyBase=FBgn0033936|UniProtKB=A1Z9R1 A1Z9R1 Achl PTHR22792:SF140 LUPUS LA PROTEIN-RELATED ACHILLES, ISOFORM A nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035997|UniProtKB=Q9VSZ3 Q9VSZ3 phol PTHR14003:SF37 TRANSCRIPTIONAL REPRESSOR PROTEIN YY YY2 TRANSCRIPTION FACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;PcG protein complex#GO:0031519;chromosome#GO:0005694 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0036614|UniProtKB=Q9VV40 Q9VV40 Golgin104 PTHR18911:SF5 CTCL TUMOR ANTIGEN HD-CL-01 COILED-COIL DOMAIN-CONTAINING PROTEIN 186 DROME|FlyBase=FBgn0040227|UniProtKB=Q9VCK0 Q9VCK0 eIF3d1 PTHR12399:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 eukaryotic translation initiation factor 3 complex#GO:0005852;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 DROME|FlyBase=FBgn0283438|UniProtKB=Q9VG01 Q9VG01 Trabd PTHR21530:SF7 PHEROMONE SHUTDOWN PROTEIN TRAB DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0040279|UniProtKB=Q9VNN6 Q9VNN6 Osi14 PTHR21879:SF17 FI03362P-RELATED-RELATED LD24139P cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0031143|UniProtKB=Q9VRD4 Q9VRD4 Dmel\CG1532 PTHR46466:SF1 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 DROME|FlyBase=FBgn0000352|UniProtKB=O16844 O16844 cos PTHR24115:SF949 KINESIN-RELATED KINESIN-LIKE PROTEIN COSTA protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631 organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Hedgehog signaling pathway#P00025>Costal2#P00698 DROME|FlyBase=FBgn0038733|UniProtKB=Q9VDU1 Q9VDU1 Acsx3 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522 ligase#PC00142 DROME|FlyBase=FBgn0035033|UniProtKB=Q9W140 Q9W140 Dmel\CG3548 PTHR21411:SF0 APONTIC REGULATORY PROTEIN ZESTE DROME|FlyBase=FBgn0285949|UniProtKB=Q9V597 Q9V597 RpL31 PTHR10956:SF0 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0022740|UniProtKB=Q0IGU7 Q0IGU7 HLH54F PTHR23349:SF72 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HLH54F sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0004381|UniProtKB=P46867 P46867 Klp68D PTHR24115:SF789 KINESIN-RELATED KINESIN-LIKE PROTEIN KLP68D protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0001085|UniProtKB=P18537 P18537 fz PTHR11309:SF47 FRIZZLED FRIZZLED protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475 DROME|FlyBase=FBgn0266346|UniProtKB=Q9W2D5 Q9W2D5 CngB PTHR45638:SF1 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED ION CHANNEL SUBUNIT B, ISOFORM A channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 ion channel#PC00133;ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0035434|UniProtKB=Q9VZR2 Q9VZR2 Drsl5 PTHR33147:SF98 DEFENSIN-LIKE PROTEIN 1 DRO1 PROTEIN-RELATED response to stress#GO:0006950;response to stimulus#GO:0050896;defense response#GO:0006952 antimicrobial response protein#PC00051 DROME|FlyBase=FBgn0043550|UniProtKB=Q8IQK9 Q8IQK9 Tsp68C PTHR19282:SF428 TETRASPANIN TETRASPANIN 68C, ISOFORM A plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0053834|UniProtKB=Q4AB94 Q4AB94 His1:CG33834 PTHR11467:SF36 HISTONE H1 H1.010 LINKER HISTONE, CLUSTER MEMBER-RELATED chromatin DNA binding#GO:0031490;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877;DNA binding#GO:0003677;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0261479|UniProtKB=Q9V9U4 Q9V9U4 nero PTHR12697:SF42 PBS LYASE HEAT-LIKE PROTEIN DEOXYHYPUSINE HYDROXYLASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 lyase#PC00144 DROME|FlyBase=FBgn0037786|UniProtKB=Q9VH28 Q9VH28 Alp13 PTHR11596:SF91 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0004598|UniProtKB=P30432 P30432 Fur2 PTHR42884:SF35 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 2 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;hormone metabolic process#GO:0042445;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 DROME|FlyBase=FBgn0035370|UniProtKB=Q9VZY0 Q9VZY0 Non2 PTHR13844:SF53 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D LD45195P membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0050259|UniProtKB=Q9W212 Q9W212 CG13522 PTHR21625:SF0 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX SUBUNIT 2 plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium or flagellum-dependent cell motility#GO:0001539;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;regulation of microtubule-based movement#GO:0060632 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0050037|UniProtKB=A1Z8R5 A1Z8R5 Dmel\CG30037 PTHR11214:SF314 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0260659|UniProtKB=E1JIL1 E1JIL1 CG4196 PTHR12608:SF1 TRANSMEMBRANE PROTEIN HTP-1 RELATED DIVALENT CATION_PROTON ANTIPORTER TMEM165-RELATED transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0004435|UniProtKB=P23625 P23625 Galphaq PTHR10218:SF365 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA Q SUBUNIT-RELATED hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165 heterotrimeric G-protein#PC00117;G-protein#PC00020 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Endothelin signaling pathway#P00019>Gq#P00586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Wnt signaling pathway#P00057>Galpha#P01451;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057 DROME|FlyBase=FBgn0038979|UniProtKB=E1JIT5 E1JIT5 tHMG2 PTHR48112:SF20 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN D-RELATED chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0033032|UniProtKB=A1Z6H0 A1Z6H0 kune PTHR21284:SF11 EG:80H7.2 PROTEIN KUNE-KUNE cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell junction organization#GO:0034330;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856 cell-cell junction#GO:0005911;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161 DROME|FlyBase=FBgn0003065|UniProtKB=Q9V9U0 Q9V9U0 GCR1 PTHR22552:SF45 GEO11429P1 RE35358P DROME|FlyBase=FBgn0037188|UniProtKB=Q7KTU3 Q7KTU3 Dmel\CG7369 PTHR23113:SF356 GUANINE NUCLEOTIDE EXCHANGE FACTOR FI05912P-RELATED molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0032297|UniProtKB=Q9VKQ5 Q9VKQ5 Dmel\CG17124 PTHR16188:SF14 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C GEO07393P1 protein serine/threonine phosphatase inhibitor activity#GO:0004865;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212 phosphatase modulator#PC00184 DROME|FlyBase=FBgn0262937|UniProtKB=Q9W0H9 Q9W0H9 Rabex-5 PTHR23101:SF122 RAB GDP/GTP EXCHANGE FACTOR RAB5 GDP_GTP EXCHANGE FACTOR binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;cytosol#GO:0005829;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0030930|UniProtKB=Q8MV48 Q8MV48 Pgant7 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0033344|UniProtKB=A1Z7K3 A1Z7K3 Dmel\CG8252 PTHR35075:SF1 A-KINASE ANCHOR PROTEIN 14 A-KINASE ANCHOR PROTEIN 14 protein binding#GO:0005515;binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237 transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0289745|UniProtKB=A0A0B4LHM3 A0A0B4LHM3 Est17 PTHR11559:SF438 CARBOXYLESTERASE CARBOXYLESTERASE esterase#PC00097 DROME|FlyBase=FBgn0031057|UniProtKB=Q9VWD9 Q9VWD9 Ubqn PTHR10677:SF3 UBIQUILIN FI07626P-RELATED protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0013762|UniProtKB=P48609 P48609 Cdk5 PTHR24056:SF594 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 5 cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;axon development#GO:0061564;vesicle localization#GO:0051648;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;organelle localization#GO:0051640;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;programmed cell death#GO:0012501;cell death#GO:0008219;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron apoptotic process#GO:0051402;cellular localization#GO:0051641;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;apoptotic process#GO:0006915;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;establishment of organelle localization#GO:0051656;cell development#GO:0048468 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Axon guidance mediated by semaphorins#P00007>Cdk5#P00336;Dopamine receptor mediated signaling pathway#P05912>CDK5#P05951;Nicotine pharmacodynamics pathway#P06587>CDK5#P06597;PDGF signaling pathway#P00047>GSK3#P01153;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902 DROME|FlyBase=FBgn0020279|UniProtKB=Q86S05 Q86S05 lig PTHR16308:SF13 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER PROTEIN LINGERER DROME|FlyBase=FBgn0003174|UniProtKB=A1Z6W9 A1Z6W9 pwn PTHR24034:SF205 EGF-LIKE DOMAIN-CONTAINING PROTEIN PAWN, ISOFORM B extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0033051|UniProtKB=Q7KHK9 Q7KHK9 Strica PTHR10454:SF251 CASPASE AT03047P-RELATED catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;biological regulation#GO:0065007;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;programmed cell death#GO:0012501;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Pro-Caspase6#P00607;FAS signaling pathway#P00020>Caspase6#P00596 DROME|FlyBase=FBgn0042092|UniProtKB=Q9VM72 Q9VM72 Polr1F PTHR12709:SF5 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0004363|UniProtKB=Q94920 Q94920 porin PTHR11743:SF70 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL GH26960P-RELATED channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803 mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;intracellular transport#GO:0046907;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0010762|UniProtKB=M9PF79 M9PF79 simj PTHR13455:SF7 TRANSCRIPTIONAL REPRESSOR P66-RELATED SIMJANG, ISOFORM E DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032116|UniProtKB=Q9VLC3 Q9VLC3 Mco1 PTHR11709:SF539 MULTI-COPPER OXIDASE FI03373P-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 oxidase#PC00175 DROME|FlyBase=FBgn0033095|UniProtKB=Q8T043 Q8T043 chk PTHR11360:SF111 MONOCARBOXYLATE TRANSPORTER CHASKI, ISOFORM A transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0029970|UniProtKB=Q9W3N8 Q9W3N8 Nek2 PTHR43671:SF115 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK2 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;cytoskeleton organization#GO:0007010;mitotic cell cycle phase transition#GO:0044772;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032693|UniProtKB=Q9VJ71 Q9VJ71 Cyp310a1 PTHR24292:SF93 CYTOCHROME P450 CYTOCHROME P450 310A1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0023517|UniProtKB=O46084 O46084 Pgam5 PTHR20935:SF0 PHOSPHOGLYCERATE MUTASE-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 positive regulation of biological process#GO:0048518;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;positive regulation of mitochondrial fission#GO:0090141;positive regulation of cellular component organization#GO:0051130;positive regulation of developmental process#GO:0051094;positive regulation of organelle organization#GO:0010638;regulation of anatomical structure morphogenesis#GO:0022603 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 isomerase#PC00135;mutase#PC00160 DROME|FlyBase=FBgn0051357|UniProtKB=Q8MSB1 Q8MSB1 Kaz PTHR12170:SF2 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0026255|UniProtKB=Q0E8N6 Q0E8N6 clumsy PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 DROME|FlyBase=FBgn0053986|UniProtKB=Q2PDY8 Q2PDY8 CG7973 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0037958|UniProtKB=Q9VGH0 Q9VGH0 Dmel\CG6962 PTHR12988:SF6 SPHINGOMYELIN PHOSPHODIESTERASE 4 SPHINGOMYELIN PHOSPHODIESTERASE 4 phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;lipase activity#GO:0016298;catalytic activity#GO:0003824 glycerolipid catabolic process#GO:0046503;ceramide metabolic process#GO:0006672;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;glycerophospholipid catabolic process#GO:0046475;cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;sphingomyelin metabolic process#GO:0006684 phosphodiesterase#PC00185 DROME|FlyBase=FBgn0265276|UniProtKB=A0A0B4KGA3 A0A0B4KGA3 l(3)neo38 PTHR23235:SF185 KRUEPPEL-LIKE TRANSCRIPTION FACTOR LETHAL (3) NEO38, ISOFORM L transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0029922|UniProtKB=A0A6H2EE55 A0A6H2EE55 Dmel\CG14431 PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED ACTIN NUCLEATION-PROMOTING FACTOR WAS-RELATED binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267 regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0004400|UniProtKB=Q7JXA8 Q7JXA8 rhi PTHR22812:SF112 CHROMOBOX PROTEIN CHROMATOR, ISOFORM A-RELATED binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0030223|UniProtKB=Q9W2S7 Q9W2S7 pepCG2111 PTHR11533:SF253 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006 primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171;catabolic process#GO:0009056;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0031488|UniProtKB=Q9VQK1 Q9VQK1 Ccdc85 PTHR13546:SF15 RE60986P CCDC85 DROME|FlyBase=FBgn0036266|UniProtKB=Q9VTV4 Q9VTV4 Tsen54 PTHR21027:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 endoribonuclease#PC00094 DROME|FlyBase=FBgn0028855|UniProtKB=Q9VJS1 Q9VJS1 Dmel\CG15282 PTHR22552:SF25 GEO11429P1 GEO11429P1-RELATED DROME|FlyBase=FBgn0035638|UniProtKB=Q8T3Z0 Q8T3Z0 Tektin-C PTHR19960:SF25 TEKTIN TEKTIN-1 cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;organelle assembly#GO:0070925;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0029091|UniProtKB=Q9VNW7 Q9VNW7 Chs2 PTHR22914:SF14 CHITIN SYNTHASE CHITIN SYNTHASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;biosynthetic process#GO:0009058;amino sugar metabolic process#GO:0006040;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;aminoglycan biosynthetic process#GO:0006023 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 transferase#PC00220 DROME|FlyBase=FBgn0036875|UniProtKB=B7Z080 B7Z080 Dmel\CG9449 PTHR11567:SF205 ACID PHOSPHATASE-RELATED GH28721P-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phosphatase#PC00181 DROME|FlyBase=FBgn0267408|UniProtKB=Q9VF53 Q9VF53 AOX1 PTHR11908:SF132 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE 1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0052843|UniProtKB=A0A0B4KF12 A0A0B4KF12 Dh31-R PTHR45620:SF32 PDF RECEPTOR-LIKE PROTEIN-RELATED DIURETIC HORMONE 31 RECEPTOR, ISOFORM C molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0020767|UniProtKB=A0A0B4KG11 A0A0B4KG11 Spred PTHR11202:SF3 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED PROTEIN WITH EVH-1 DOMAIN, ISOFORM C protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0290182|UniProtKB=P45975 P45975 Su(var)3-9 PTHR46223:SF4 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0037648|UniProtKB=Q9VHJ2 Q9VHJ2 Dmel\CG11975 PTHR11227:SF18 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 3 phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;energy derivation by oxidation of organic compounds#GO:0015980;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;localization#GO:0051179;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038672|UniProtKB=Q9VE12 Q9VE12 Dmel\CG6005 PTHR13083:SF3 WD REPEAT-CONTAINING PROTEIN 91 WD REPEAT-CONTAINING PROTEIN 91 enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;early endosome membrane#GO:0031901;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 DROME|FlyBase=FBgn0052418|UniProtKB=Q8SWS7 Q8SWS7 vito PTHR14577:SF0 NUCLEOLAR PROTEIN 12 NUCLEOLAR PROTEIN 12 rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 DROME|FlyBase=FBgn0050277|UniProtKB=Q9W271 Q9W271 Oatp58Da PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0033476|UniProtKB=Q6NN55 Q6NN55 oys PTHR13906:SF4 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 6 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;membrane#GO:0016020 acetyltransferase#PC00038 DROME|FlyBase=FBgn0039916|UniProtKB=Q0KIF2 Q0KIF2 Ekar PTHR18966:SF607 IONOTROPIC GLUTAMATE RECEPTOR EYE-ENRICHED KAINATE RECEPTOR, ISOFORM B monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0016693|UniProtKB=Q8T8W3 Q8T8W3 Past1 PTHR11216:SF178 EH DOMAIN AT21416P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endocytic recycling#GO:0032456;cell projection organization#GO:0030030;endocytosis#GO:0006897;protein localization to membrane#GO:0072657;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;localization within membrane#GO:0051668;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;plasma membrane bounded cell projection organization#GO:0120036;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;transport#GO:0006810 recycling endosome#GO:0055037;organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0261111|UniProtKB=Q9VS33 Q9VS33 BHD PTHR31441:SF3 FOLLICULIN FAMILY MEMBER FOLLICULIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 positive regulation of signal transduction#GO:0009967;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of TOR signaling#GO:0032008;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of TORC1 signaling#GO:1903432;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of signaling#GO:0023056;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0029736|UniProtKB=Q9W4F8 Q9W4F8 Dmel\CG4041 PTHR22957:SF168 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0024996|UniProtKB=O76863 O76863 eIF2Bbeta PTHR45859:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT BETA enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;guanyl-nucleotide exchange factor activity#GO:0005085;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 translation initiation factor#PC00224 DROME|FlyBase=FBgn0037632|UniProtKB=Q9VHL2 Q9VHL2 CCT7 PTHR11353:SF22 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ETA protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein folding chaperone complex#GO:0101031;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832 chaperonin#PC00073 DROME|FlyBase=FBgn0261016|UniProtKB=A8DQW8 A8DQW8 clos PTHR15261:SF4 THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0004401|UniProtKB=P41073 P41073 Pep PTHR15491:SF20 FAMILY NOT NAMED ZINC FINGER PROTEIN ON ECDYSONE PUFFS regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0028554|UniProtKB=Q9V3V0 Q9V3V0 x16 PTHR23147:SF189 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE-RICH-SPLICING FACTOR 3A-RELATED ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0036494|UniProtKB=Q9VUN0 Q9VUN0 Toll-6 PTHR45836:SF8 SLIT HOMOLOG TOLL-LIKE RECEPTOR 6 protein binding#GO:0005515;heparin binding#GO:0008201;signaling receptor binding#GO:0005102;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367 neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0039932|UniProtKB=D1YSG4 D1YSG4 fuss PTHR10005:SF26 SKI ONCOGENE-RELATED CORL sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;negative regulation of BMP signaling pathway#GO:0030514;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of BMP signaling pathway#GO:0030510;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039840|UniProtKB=Q9V9Y4 Q9V9Y4 pHCl-2 PTHR18945:SF843 NEUROTRANSMITTER GATED ION CHANNEL PH-SENSITIVE CHLORIDE CHANNEL 2 monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0020236|UniProtKB=Q7KN85 Q7KN85 Acly PTHR23118:SF42 ATP-CITRATE SYNTHASE ATP-CITRATE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;monocarboxylic acid biosynthetic process#GO:0072330;nucleoside phosphate biosynthetic process#GO:1901293;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;fatty acid biosynthetic process#GO:0006633;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220 Pyruvate metabolism#P02772>Citrate Lyase#P03137 DROME|FlyBase=FBgn0039687|UniProtKB=Q9VAI4 Q9VAI4 Naa40 PTHR20531:SF1 N-ALPHA-ACETYLTRANSFERASE 40 N-ALPHA-ACETYLTRANSFERASE 40 N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0053647|UniProtKB=Q4ABJ8 Q4ABJ8 Dmel\CG33647 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0030270|UniProtKB=Q9VZ26 Q9VZ26 DIGF-3 PTHR39957:SF2 AT09846P1-RELATED GEO11553P1 DROME|FlyBase=FBgn0027066|UniProtKB=A1Z6P3 A1Z6P3 Eb1 PTHR10623:SF6 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER EB1, ISOFORM F-RELATED tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cell cycle#GO:0007049;protein localization to cytoskeleton#GO:0044380;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;chromosome segregation#GO:0007059;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0051251|UniProtKB=Q8IN95 Q8IN95 Dmel\CG31251 PTHR12356:SF19 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 3 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0026313|UniProtKB=X2JE74 X2JE74 X11L PTHR12345:SF16 SYNTENIN RELATED X11L, ISOFORM F-RELATED cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell junction#GO:0030054;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic spine#GO:0043197;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0039679|UniProtKB=Q9VAJ3 Q9VAJ3 ppk19 PTHR11690:SF253 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 18-RELATED channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0039927|UniProtKB=Q9V4A0 Q9V4A0 ukar PTHR18966:SF589 IONOTROPIC GLUTAMATE RECEPTOR FI01405P channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594 regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0037255|UniProtKB=Q9VN31 Q9VN31 Fip1 PTHR13484:SF11 FIP1-LIKE 1 PROTEIN FACTOR INTERACTING WITH POLY(A) POLYMERASE 1 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0033093|UniProtKB=A1Z6N5 A1Z6N5 Dmel\CG3270 PTHR13847:SF294 SARCOSINE DEHYDROGENASE-RELATED FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydrogenase#PC00092 DROME|FlyBase=FBgn0037898|UniProtKB=Q9VGP0 Q9VGP0 Dtd PTHR10472:SF5 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 DROME|FlyBase=FBgn0017456|UniProtKB=P52487 P52487 Ubc84D PTHR24068:SF116 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>UbcH8#P01223;Parkinson disease#P00049>UbcH7#P01224 DROME|FlyBase=FBgn0033387|UniProtKB=B7YZU3 B7YZU3 Dmel\CG8008 PTHR23507:SF39 ZGC:174356 GH23453P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cellular anatomical structure#GO:0110165 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0000239|UniProtKB=Q9VIE7 Q9VIE7 bur PTHR11922:SF6 GMP SYNTHASE-RELATED GMP SYNTHASE [GLUTAMINE-HYDROLYZING] ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 De novo purine biosynthesis#P02738>GMP synthase#P02899 DROME|FlyBase=FBgn0036622|UniProtKB=Q9VV49 Q9VV49 Agpat4 PTHR10983:SF24 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 3, ISOFORM E-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0041789|UniProtKB=Q2PDT4 Q2PDT4 Pax PTHR24216:SF69 PAXILLIN-RELATED PAXILLIN, ISOFORM F protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418;Integrin signalling pathway#P00034>Paxillin#P00950 DROME|FlyBase=FBgn0000061|UniProtKB=Q06453 Q06453 al PTHR24329:SF579 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0051715|UniProtKB=Q8MYY7 Q8MYY7 BcDNA:RE44624 PTHR24189:SF69 MYOTROPHIN MYOTROPHIN regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament depolymerization#GO:0030834;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of protein depolymerization#GO:1901879;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0032587|UniProtKB=Q9VJK4 Q9VJK4 Dmel\CG5953 PTHR21505:SF8 MADF DOMAIN-CONTAINING PROTEIN-RELATED DPT-YFP REPRESSOR BY OVEREXPRESSION, ISOFORM D-RELATED DROME|FlyBase=FBgn0261064|UniProtKB=Q9VLS5 Q9VLS5 Rbsn-5 PTHR13510:SF44 FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED RABENOSYN-5 DROME|FlyBase=FBgn0287828|UniProtKB=P83099 P83099 Pkcdelta PTHR24356:SF347 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C DELTA TYPE HOMOLOG-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;FGF signaling pathway#P00021>PKC#P00648;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Endothelin signaling pathway#P00019>PKC#P00568;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;Apoptosis signaling pathway#P00006>PKCs#P00318 DROME|FlyBase=FBgn0051626|UniProtKB=Q8INT9 Q8INT9 BcDNA:RE20756 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0043470|UniProtKB=Q7JPN9 Q7JPN9 lambdaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032597|UniProtKB=Q9VJI9 Q9VJI9 Nubp1 PTHR23264:SF35 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1 iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028938|UniProtKB=Q9V3G8 Q9V3G8 Vajk1 PTHR47771:SF16 LD27203P-RELATED RH73259P binding#GO:0005488;carbohydrate derivative binding#GO:0097367 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 DROME|FlyBase=FBgn0063491|UniProtKB=Q7K8X7 Q7K8X7 GstE9 PTHR43969:SF4 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED FI01423P-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0050438|UniProtKB=Q8SYL7 Q8SYL7 Ugt50B3 PTHR48043:SF27 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0039519|UniProtKB=Q9VB31 Q9VB31 Cyp6a18 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034308|UniProtKB=Q8SX68 Q8SX68 Naus PTHR23166:SF5 FILAMIN/GPBP-INTERACTING PROTEIN CTTNBP2 N-TERMINAL-LIKE PROTEIN protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 DROME|FlyBase=FBgn0039829|UniProtKB=Q9V9Z8 Q9V9Z8 Dmel\CG15561 PTHR23149:SF9 G PATCH DOMAIN CONTAINING PROTEIN G PATCH DOMAIN-CONTAINING PROTEIN 4 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0025874|UniProtKB=O96395 O96395 Meics PTHR24377:SF1046 IP01015P-RELATED FI01202P-RELATED C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0032646|UniProtKB=Q9VJC7 Q9VJC7 mEFTs PTHR11741:SF0 ELONGATION FACTOR TS ELONGATION FACTOR TS, MITOCHONDRIAL translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation elongation factor#PC00222 DROME|FlyBase=FBgn0035279|UniProtKB=Q9W079 Q9W079 Cpr62Ba PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0029961|UniProtKB=Q9W3P8 Q9W3P8 Ir7a PTHR42643:SF52 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 11A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0033000|UniProtKB=Q5LJQ3 Q5LJQ3 BcDNA:LD29015 PTHR46536:SF3 ARL14 EFFECTOR PROTEIN ARF7 EFFECTOR PROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0038318|UniProtKB=Q9VF91 Q9VF91 gi23171351 PTHR10974:SF78 FI08016P-RELATED FI21235P1 DROME|FlyBase=FBgn0053556|UniProtKB=A8JNM1 A8JNM1 form3 PTHR46345:SF12 INVERTED FORMIN-2 FORMIN 3, ISOFORM B DROME|FlyBase=FBgn0034650|UniProtKB=Q9W2E3 Q9W2E3 NC2alpha PTHR10252:SF163 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DR1-ASSOCIATED COREPRESSOR DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0265182|UniProtKB=Q9W0Z5 Q9W0Z5 Atf-2 PTHR23352:SF2 NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN-1 NPDC-1 PROTEIN NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN 1 DROME|FlyBase=FBgn0032348|UniProtKB=Q9VKJ1 Q9VKJ1 CG4751 PTHR23216:SF2 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0262508|UniProtKB=M9NFP8 M9NFP8 CG17926 PTHR34491:SF156 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED AUGMIN COMPLEX SUBUNIT DGT5 DROME|FlyBase=FBgn0010328|UniProtKB=A8JRE3 A8JRE3 woc PTHR45736:SF1 ZINC FINGER MYM-TYPE PROTEIN WITHOUT CHILDREN, ISOFORM B zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032210|UniProtKB=Q8IPC5 Q8IPC5 CYLD PTHR11830:SF3 40S RIBOSOMAL PROTEIN S3A UBIQUITINYL HYDROLASE 1 structural constituent of ribosome#GO:0003735;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;structural molecule activity#GO:0005198;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0038039|UniProtKB=Q9VG80 Q9VG80 Dmel\CG5196 PTHR22883:SF23 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC6 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0025625|UniProtKB=Q9W532 Q9W532 Sik2 PTHR24343:SF299 SERINE/THREONINE KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0036195|UniProtKB=M9PC80 M9PC80 Dnai2 PTHR12442:SF7 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;cilium movement#GO:0003341;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858;membraneless organelle#GO:0043228;outer dynein arm#GO:0036157;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0032799|UniProtKB=Q9VIU7 Q9VIU7 Dpm1 PTHR43398:SF1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0025595|UniProtKB=Q7KTL9 Q7KTL9 AkhR PTHR24241:SF197 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ADIPOKINETIC HORMONE RECEPTOR, ISOFORM C G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 DROME|FlyBase=FBgn0037612|UniProtKB=Q8MYW9 Q8MYW9 ACAT PTHR10408:SF8 STEROL O-ACYLTRANSFERASE O-ACYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;sterol metabolic process#GO:0016125;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;steroid metabolic process#GO:0008202 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0038752|UniProtKB=Q9VDS0 Q9VDS0 Dmel\CG4462 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0035703|UniProtKB=Q9VRX1 Q9VRX1 Bulli PTHR12897:SF4 COLON CANCER-ASSOCIATED PROTEIN MIC1 REGULATOR OF MON1-CCZ1 COMPLEX structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of catabolic process#GO:0009894;biological regulation#GO:0065007 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;late endosome membrane#GO:0031902;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 DROME|FlyBase=FBgn0020386|UniProtKB=Q9W0V1 Q9W0V1 Pdk1 PTHR24356:SF449 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700 non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>PDK1/2#P04616;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;PI3 kinase pathway#P00048>P110ACT#P01177;Ras Pathway#P04393>PDK#P04555;Interleukin signaling pathway#P00036>PDK1/2#P00985;PI3 kinase pathway#P00048>PDK1#P01196;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PDGF signaling pathway#P00047>PDK1/2#P01164;p53 pathway feedback loops 2#P04398>PDK1/2#P04656 DROME|FlyBase=FBgn0032881|UniProtKB=Q9VIK0 Q9VIK0 Amacr PTHR48228:SF8 SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE ALPHA-METHYLACYL-COA RACEMASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824 steroid metabolic process#GO:0008202;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 DROME|FlyBase=FBgn0034758|UniProtKB=Q9W221 Q9W221 Dmel\CG13510 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;zinc ion binding#GO:0008270 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033819|UniProtKB=A1Z9B2 A1Z9B2 Dmel\CG4714 PTHR15654:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 184 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0013305|UniProtKB=Q7JRM9 Q7JRM9 Nmda1 PTHR23291:SF131 BAX INHIBITOR-RELATED TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7 calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0038909|UniProtKB=Q9VD71 Q9VD71 Dmel\CG6569 PTHR10881:SF46 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 2 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0052406|UniProtKB=Q9VRS2 Q9VRS2 PVRAP PTHR45734:SF7 TENSIN EGFR ADAPTER PROTEIN-RELATED focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0035471|UniProtKB=Q9VZL3 Q9VZL3 Tecr PTHR10556:SF28 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE VERY-LONG-CHAIN ENOYL-COA REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 DROME|FlyBase=FBgn0035286|UniProtKB=M9MRP4 M9MRP4 Dmel\CG13924 PTHR14320:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 DROME|FlyBase=FBgn0040212|UniProtKB=A0A0B4KHK0 A0A0B4KHK0 Gnpat PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032768|UniProtKB=Q9VIY3 Q9VIY3 Dmel\CG17564 PTHR21683:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 42 HOMOLOG ISOFORM X1 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0051633|UniProtKB=Q9VMA6 Q9VMA6 CG13770 PTHR38926:SF87 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6 binding#GO:0005488;protein-containing complex binding#GO:0044877 DROME|FlyBase=FBgn0016675|UniProtKB=Q9VIX1 Q9VIX1 Lectin-galC1 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN binding#GO:0005488;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0288310|UniProtKB=Q9W060 Q9W060 mv PTHR13743:SF86 BEIGE/BEACH-RELATED LYSOSOMAL-TRAFFICKING REGULATOR cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;lysosome organization#GO:0007040;lytic vacuole organization#GO:0080171 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038319|UniProtKB=Q9VF89 Q9VF89 mRpL9 PTHR21368:SF27 50S RIBOSOMAL PROTEIN L9 LARGE RIBOSOMAL SUBUNIT PROTEIN BL9M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0029914|UniProtKB=E1JJF2 E1JJF2 Dmel\CG4558 PTHR35259:SF3 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 MECH2 PROTEIN DROME|FlyBase=FBgn0264342|UniProtKB=M9PBZ7 M9PBZ7 lincRNA.43 PTHR45828:SF56 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE DEFENSE PROTEIN L(2)34FC membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0028926|UniProtKB=Q9VJQ5 Q9VJQ5 NC2beta PTHR46138:SF1 PROTEIN DR1 PROTEIN DR1 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053 DROME|FlyBase=FBgn0013751|UniProtKB=Q8IRC7 Q8IRC7 Awh PTHR24208:SF127 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN AWH sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0287774|UniProtKB=Q6NQY9 Q6NQY9 cg9143 PTHR24031:SF91 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX24 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0286071|UniProtKB=Q8SXB0 Q8SXB0 AdamTS-A PTHR13723:SF278 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF A, ISOFORM B catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0044011|UniProtKB=Q8SYY7 Q8SYY7 Spn43Ad PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0031479|UniProtKB=Q9VQI7 Q9VQI7 Prx6a PTHR43503:SF4 MCG48959-RELATED PEROXIREDOXIN-6 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176;peroxidase#PC00180 DROME|FlyBase=FBgn0029176|UniProtKB=Q9NJH0 Q9NJH0 eEF1gamma PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0050050|UniProtKB=A1Z8Z4 A1Z8Z4 Dmel\CG30050 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0031187|UniProtKB=Q8IQ27 Q8IQ27 Usp2 PTHR21646:SF114 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE USP2 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 DROME|FlyBase=FBgn0051632|UniProtKB=Q9VM77 Q9VM77 sens-2 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0033521|UniProtKB=A1Z893 A1Z893 Dmel\CG12896 PTHR43503:SF3 MCG48959-RELATED 1-CYS PEROXIREDOXIN oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 peroxidase#PC00180;oxidoreductase#PC00176 DROME|FlyBase=FBgn0033259|UniProtKB=Q6NP91 Q6NP91 Tmem63 PTHR13018:SF5 PROBABLE MEMBRANE PROTEIN DUF221-RELATED MECHANOSENSITIVE CATION CHANNEL TMEM63 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium-activated cation channel activity#GO:0005227 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0259164|UniProtKB=Q9VRT4 Q9VRT4 CG6596 PTHR24064:SF316 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0010288|UniProtKB=P35122 P35122 Uch PTHR10589:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0024249|UniProtKB=Q0IGT4 Q0IGT4 cato PTHR19290:SF162 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR AMOS-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0038301|UniProtKB=Q9VFB9 Q9VFB9 Dmel\CG6654 PTHR24390:SF278 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 772 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0036922|UniProtKB=Q9VW61 Q9VW61 Dmel\CG14182 PTHR31186:SF1 MODULATOR OF SMOOTHENED PROTEIN MODULATOR OF SMOOTHENED PROTEIN regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 plasma membrane#GO:0005886;cytoplasm#GO:0005737;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection membrane#GO:0031253;cilium#GO:0005929;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0030792|UniProtKB=Q9VXA9 Q9VXA9 Q9VXA9 PTHR24073:SF128 DRAB5-RELATED RAB-LIKE PROTEIN 3 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0045486|UniProtKB=Q9VJF2 Q9VJF2 Gr36b PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0263864|UniProtKB=Q7KLI1 Q7KLI1 Dark PTHR22845:SF5 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 FAS signaling pathway#P00020>Apaf1#P00597;Apoptosis signaling pathway#P00006>Apaf-1#P00301;Huntington disease#P00029>Apaf-1#P00768;p53 pathway#P00059>Apaf#G04703 DROME|FlyBase=FBgn0033782|UniProtKB=Q7K0S9 Q7K0S9 sug PTHR19818:SF84 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN GLIS2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0039075|UniProtKB=Q9VCM6 Q9VCM6 Dmel\CG4393 PTHR24174:SF1 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 IP14385P signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035147|UniProtKB=Q9W0P5 Q9W0P5 Gale PTHR43725:SF58 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857 carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 epimerase/racemase#PC00096 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 DROME|FlyBase=FBgn0038183|UniProtKB=Q9VFR0 Q9VFR0 CG9286 PTHR13261:SF0 BRCA2 AND CDKN1A INTERACTING PROTEIN BRCA2 AND CDKN1A-INTERACTING PROTEIN enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 microtubule cytoskeleton organization#GO:0000226;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;regulation of protein modification process#GO:0031399;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule anchoring#GO:0034453;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0030340|UniProtKB=Q9VYT7 Q9VYT7 Dmel\CG15740 PTHR23157:SF25 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0031283|UniProtKB=Q9VPT6 Q9VPT6 Dmel\CG15880 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 ACYLTRANSFERASE PGAP2 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003391|UniProtKB=Q24298 Q24298 shg PTHR24026:SF118 FAT ATYPICAL CADHERIN-RELATED DE-CADHERIN cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;system development#GO:0048731;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell-cell junction#GO:0005911 cadherin#PC00057 Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118;Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 DROME|FlyBase=FBgn0050025|UniProtKB=A1Z8J8 A1Z8J8 Dmel\CG30025 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0265575|UniProtKB=P91679 P91679 yin PTHR11654:SF678 OLIGOPEPTIDE TRANSPORTER-RELATED PEPTIDE TRANSPORTER FAMILY 1 oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 import across plasma membrane#GO:0098739;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transport#GO:0006857;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;dipeptide transport#GO:0042938;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 transporter#PC00227 DROME|FlyBase=FBgn0031571|UniProtKB=M9NDE3 M9NDE3 bark PTHR47653:SF1 PROTEIN BARK BEETLE PROTEIN BARK BEETLE cellular process#GO:0009987;cell-cell junction organization#GO:0045216;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037594|UniProtKB=Q9VHQ2 Q9VHQ2 Or85d PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0029879|UniProtKB=Q9W3Y6 Q9W3Y6 APC7 PTHR12558:SF36 CELL DIVISION CYCLE 16,23,27 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein modification by small protein conjugation or removal#GO:0070647;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;positive regulation of cell cycle process#GO:0090068;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;metabolic process#GO:0008152;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of chromosome separation#GO:1905818;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;cell division#GO:0051301;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;regulation of mitotic metaphase/anaphase transition#GO:0030071;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035208|UniProtKB=Q9W0H1 Q9W0H1 Dmel\CG9184 PTHR31395:SF26 SHISA GEO05642P1-RELATED scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033639|UniProtKB=A8DYA6 A8DYA6 Dmel\CG9003 PTHR13318:SF165 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN FBXL-1 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0033473|UniProtKB=A1Z830 A1Z830 ptch PTHR12150:SF13 CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED 28S RRNA (URIDINE-N(3))-METHYLTRANSFERASE metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 DROME|FlyBase=FBgn0003274|UniProtKB=P05389 P05389 RpLP2 PTHR21141:SF5 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN P2 ribosomal protein#PC00202 DROME|FlyBase=FBgn0023479|UniProtKB=Q9VSU2 Q9VSU2 teq PTHR24258:SF128 SERINE PROTEASE-RELATED TEQUILA, ISOFORM G protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0038105|UniProtKB=Q9VG08 Q9VG08 yellow-f2 PTHR10009:SF10 PROTEIN YELLOW-RELATED L-DOPACHROME TAUTOMERASE YELLOW-F-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0028664|UniProtKB=Q9VZG7 Q9VZG7 VhaM9.7-c PTHR12263:SF0 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0003042|UniProtKB=P26017 P26017 Pc PTHR46389:SF3 POLYCOMB GROUP PROTEIN PC POLYCOMB GROUP PROTEIN PC chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0030839|UniProtKB=Q9VX51 Q9VX51 ENGase PTHR13246:SF1 ENDO BETA N-ACETYLGLUCOSAMINIDASE CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 deaminase#PC00088;hydrolase#PC00121 DROME|FlyBase=FBgn0263999|UniProtKB=A0A0B4KFF2 A0A0B4KFF2 Dmel\CG43742 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0003165|UniProtKB=P25822 P25822 pum PTHR12537:SF195 RNA BINDING PROTEIN PUMILIO-RELATED MATERNAL PROTEIN PUMILIO binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0003321|UniProtKB=Q9U1H9 Q9U1H9 sbr PTHR10662:SF22 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0036581|UniProtKB=Q9GYU7 Q9GYU7 MED10 PTHR13345:SF13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0026144|UniProtKB=M9PHB8 M9PHB8 CBP PTHR23064:SF86 TROPONIN SARCOPLASMIC CALCIUM-BINDING PROTEIN, ISOFORM C actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0028950|UniProtKB=Q9V445 Q9V445 Dmel\CG15255 PTHR10127:SF914 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0034300|UniProtKB=Q6AWG9 Q6AWG9 CG5098 PTHR14955:SF4 RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20 PHD-TYPE DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0039629|UniProtKB=Q9VAQ3 Q9VAQ3 SP68 PTHR24260:SF147 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED DROME|FlyBase=FBgn0031729|UniProtKB=Q9VMN4 Q9VMN4 Dmel\CG12511 PTHR21346:SF0 FUN14 DOMAIN CONTAINING RE45833P process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;autophagy#GO:0006914;cellular process#GO:0009987;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422 organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 DROME|FlyBase=FBgn0031872|UniProtKB=Q9VM64 Q9VM64 ihog PTHR10075:SF131 BASIGIN RELATED INTERFERENCE HEDGEHOG cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0041229|UniProtKB=Q9VD76 Q9VD76 Gr93a PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0052212|UniProtKB=Q8IQU5 Q8IQU5 Dmel\CG32212 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0039564|UniProtKB=Q9VAY0 Q9VAY0 Nep7 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0039859|UniProtKB=Q9V9V9 Q9V9V9 Mnat9 PTHR13256:SF16 N-ACETYLTRANSFERASE 9 ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407 regulation of microtubule polymerization or depolymerization#GO:0031110;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of organelle organization#GO:0010638;regulation of microtubule polymerization#GO:0031113;regulation of microtubule-based process#GO:0032886;positive regulation of cellular component organization#GO:0051130;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 DROME|FlyBase=FBgn0050045|UniProtKB=A8DRW0 A8DRW0 Cpr49Aa PTHR10380:SF242 CUTICLE PROTEIN CUTICULAR PROTEIN 47EG-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0260392|UniProtKB=E1JGK8 E1JGK8 CG5134 PTHR41161:SF1 PROTEIN NCBP2AS2 PROTEIN NCBP2AS2 DROME|FlyBase=FBgn0030715|UniProtKB=Q9VXL0 Q9VXL0 Or13a PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038723|UniProtKB=Q9VDV2 Q9VDV2 Dmel\CG6195 PTHR43127:SF2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0031301|UniProtKB=Q9VPW5 Q9VPW5 Dmel\CG14339 PTHR44314:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018 cilium#GO:0005929;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 DROME|FlyBase=FBgn0040257|UniProtKB=Q9VGT4 Q9VGT4 Ugt302E1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 DROME|FlyBase=FBgn0050087|UniProtKB=A1ZA39 A1ZA39 Dmel\CG30087 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0001137|UniProtKB=P42287 P42287 grk PTHR12332:SF1 KEREN-RELATED KEREN-RELATED cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 DROME|FlyBase=FBgn0275436|UniProtKB=O16129 O16129 PheRS-m PTHR11538:SF41 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0035679|UniProtKB=Q9VRU1 Q9VRU1 Galm2 PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;carbohydrate catabolic process#GO:0016052;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975 epimerase/racemase#PC00096 DROME|FlyBase=FBgn0083960|UniProtKB=Q0E8T7 Q0E8T7 CG31652 PTHR13720:SF18 WD-40 REPEAT PROTEIN FI23230P1 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0266757|UniProtKB=B7Z0E5 B7Z0E5 mfr PTHR12546:SF60 FER-1-LIKE MISFIRE, ISOFORM F cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0015776|UniProtKB=Q24046 Q24046 nrv1 PTHR11523:SF31 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1 ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771 plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0000318|UniProtKB=Q9VMQ9 Q9VMQ9 cl PTHR12452:SF0 42-9-9 PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17 disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transporter#PC00227 DROME|FlyBase=FBgn0035249|UniProtKB=Q9W0B6 Q9W0B6 Dmel\CG17249 PTHR13621:SF2 PROLINE-RICH PROTEIN PRCC PROLINE-RICH PROTEIN PRCC intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0037313|UniProtKB=Q9VNA4 Q9VNA4 CG1161 PTHR13064:SF6 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER TRANSMEMBRANE PROTEIN 9 DROME|FlyBase=FBgn0026400|UniProtKB=Q9VAU9 Q9VAU9 Noa36 PTHR13214:SF1 ZINC FINGER PROTEIN 330 ZINC FINGER PROTEIN 330 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0037414|UniProtKB=Q9VNM7 Q9VNM7 Osi7 PTHR21879:SF22 FI03362P-RELATED-RELATED FI03362P-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033762|UniProtKB=A1Z935 A1Z935 ZnT49B PTHR13414:SF9 HUEL-CATION TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A9, MITOCHONDRIAL inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;zinc ion transport#GO:0006829 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0024944|UniProtKB=Q7JQF1 Q7JQF1 Oamb PTHR24247:SF249 5-HYDROXYTRYPTAMINE RECEPTOR OCTOPAMINE RECEPTOR OAMB molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268 plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0243516|UniProtKB=A8DYL3 A8DYL3 Vrp1 PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED ACTIN NUCLEATION-PROMOTING FACTOR WAS-RELATED protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488 regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0041245|UniProtKB=P58960 P58960 Gr39b PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;neuron projection#GO:0043005;cell body#GO:0044297;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0036697|UniProtKB=Q9VVE2 Q9VVE2 rogdi PTHR13618:SF1 LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1 PROTEIN ROGDI HOMOLOG intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0051413|UniProtKB=Q8IMY4 Q8IMY4 Qsox4 PTHR22897:SF8 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;extracellular matrix assembly#GO:0085029;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;extracellular structure organization#GO:0043062 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 DROME|FlyBase=FBgn0051612|UniProtKB=Q9V9Q2 Q9V9Q2 CG11631 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0033657|UniProtKB=Q5U154 Q5U154 Sln PTHR11360:SF306 MONOCARBOXYLATE TRANSPORTER RE01051P transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0031472|UniProtKB=Q9VQI0 Q9VQI0 Dmel\CG2983 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 transferase#PC00220 DROME|FlyBase=FBgn0031606|UniProtKB=Q9VQZ8 Q9VQZ8 Dmel\CG15439 PTHR13793:SF150 PHD FINGER PROTEINS PHD FINGER PROTEIN 14 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0005778|UniProtKB=Q9W2A5 Q9W2A5 PpD5 PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE-RELATED catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 DROME|FlyBase=FBgn0022787|UniProtKB=Q9VF02 Q9VF02 Hel89B PTHR36498:SF1 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 DROME|FlyBase=FBgn0042138|UniProtKB=M9PEW1 M9PEW1 Apt1 PTHR10655:SF68 LYSOPHOSPHOLIPASE-RELATED PALMITOYL-PROTEIN HYDROLASE palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 biological regulation#GO:0065007;negative regulation of protein transport#GO:0051224;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;negative regulation of transport#GO:0051051;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of protein localization to membrane#GO:1905475;negative regulation of biological process#GO:0048519;regulation of establishment of protein localization#GO:0070201;regulation of transport#GO:0051049;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lipase#PC00143;phospholipase#PC00186 DROME|FlyBase=FBgn0037845|UniProtKB=Q9VGV6 Q9VGV6 Dmel\CG14694 PTHR10686:SF18 FOLATE TRANSPORTER IP11787P-RELATED transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0003169|UniProtKB=Q24468 Q24468 put PTHR23255:SF98 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE PUT signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;activin binding#GO:0048185;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089 multicellular organism development#GO:0007275;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;activin receptor signaling pathway#GO:0032924;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 transferase complex, transferring phosphorus-containing groups#GO:0061695;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;ALP23B signaling pathway#P06209>PUT#P06218;GBB signaling pathway#P06214>PUT#P06304;SCW signaling pathway#P06216>PUT#P06320;DPP signaling pathway#P06213>PUT#P06277;DPP-SCW signaling pathway#P06212>PUT#P06270;BMP/activin signaling pathway-drosophila#P06211>TGFbetaR II#P06255;Activin beta signaling pathway#P06210>PUT#P06229 DROME|FlyBase=FBgn0001253|UniProtKB=Q7KUB3 Q7KUB3 ImpE1 PTHR39069:SF10 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A ECDYSONE-INDUCIBLE GENE E1, ISOFORM A DROME|FlyBase=FBgn0029763|UniProtKB=Q9W4C3 Q9W4C3 Usp16-45 PTHR24006:SF781 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16_45 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 DROME|FlyBase=FBgn0030655|UniProtKB=Q9VXT5 Q9VXT5 CG9213 PTHR12072:SF5 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 2 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 DROME|FlyBase=FBgn0039523|UniProtKB=A0A0B4KH42 A0A0B4KH42 Dmel\CG12885 PTHR23356:SF16 DPY30-RELATED DPY30 DOMAIN-CONTAINING PROTEIN 1 cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0025741|UniProtKB=Q9V491 Q9V491 PlexA PTHR22625:SF72 PLEXIN PLEXIN A, ISOFORM A transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;synapse assembly#GO:0007416;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell differentiation#GO:0045595;neuron projection morphogenesis#GO:0048812;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;anatomical structure development#GO:0048856;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;signaling#GO:0023052;cell projection organization#GO:0030030;cell differentiation#GO:0030154;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;cellular developmental process#GO:0048869;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell adhesion#GO:0007162;axon development#GO:0061564;system development#GO:0048731;regulation of nervous system development#GO:0051960;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0085257|UniProtKB=Q6IGN6 Q6IGN6 Dmel\CG34228 PTHR28599:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 12 SMALL INTEGRAL MEMBRANE PROTEIN 12 DROME|FlyBase=FBgn0031515|UniProtKB=Q0E8U2 Q0E8U2 Dmel\CG9664 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0038099|UniProtKB=Q9VG14 Q9VG14 Dmel\CG7091 PTHR11662:SF461 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0263200|UniProtKB=Q9VMA2 Q9VMA2 Galt PTHR11943:SF1 GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 nucleotidyltransferase#PC00174 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Fructose galactose metabolism#P02744>Hexose 1-P uridyltransferase#P02964 DROME|FlyBase=FBgn0038655|UniProtKB=Q9VE30 Q9VE30 Dmel\CG14297 PTHR11717:SF29 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE ARGININE PHOSPHATASE-RELATED protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 protein phosphatase#PC00195 DROME|FlyBase=FBgn0033480|UniProtKB=Q7K0A0 Q7K0A0 mRpL42 PTHR13450:SF4 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L42 LARGE RIBOSOMAL SUBUNIT PROTEIN ML42 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0032075|UniProtKB=Q9VLH0 Q9VLH0 Tsp29Fb PTHR19282:SF28 TETRASPANIN TETRASPANIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0041240|UniProtKB=Q9V969 Q9V969 Gr57a PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0033302|UniProtKB=Q9V4U7 Q9V4U7 Cyp6a14 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0261119|UniProtKB=Q7KLW9 Q7KLW9 Prp19 PTHR43995:SF1 PRE-MRNA-PROCESSING FACTOR 19 PRE-MRNA-PROCESSING FACTOR 19 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA processing factor#PC00147;RNA metabolism protein#PC00031 mRNA splicing#P00058>U4#P01476 DROME|FlyBase=FBgn0086707|UniProtKB=Q9VJ87 Q9VJ87 ncm PTHR18034:SF3 CELL CYCLE CONTROL PROTEIN CWF22-RELATED PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA processing factor#PC00147 DROME|FlyBase=FBgn0030313|UniProtKB=Q9VYX3 Q9VYX3 Reepl1 PTHR12300:SF161 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN membrane traffic protein#PC00150 DROME|FlyBase=FBgn0032614|UniProtKB=Q8IGQ3 Q8IGQ3 Dmel\CG13284 PTHR43899:SF9 RH59310P MIP25013P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0032639|UniProtKB=Q9VJD6 Q9VJD6 Dmel\CG18563 PTHR24256:SF462 TRYPTASE-RELATED LP21446P-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0051148|UniProtKB=Q9VCJ4 Q9VCJ4 Gba1a PTHR11069:SF23 GLUCOSYLCERAMIDASE LYSOSOMAL ACID GLUCOSYLCERAMIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative catabolic process#GO:1901136;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 DROME|FlyBase=FBgn0036888|UniProtKB=Q9VW13 Q9VW13 Dmel\CG9330 PTHR19211:SF117 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 translation elongation factor#PC00222 DROME|FlyBase=FBgn0020415|UniProtKB=Q9V3D4 Q9V3D4 Idgf2 PTHR11177:SF235 CHITINASE CHITINASE-LIKE PROTEIN IDGF1-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 DROME|FlyBase=FBgn0036857|UniProtKB=Q8SXQ1 Q8SXQ1 Aldh7A1 PTHR43521:SF9 ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 DROME|FlyBase=FBgn0010379|UniProtKB=Q8INB9 Q8INB9 Akt PTHR24356:SF442 SERINE/THREONINE-PROTEIN KINASE RAC SERINE_THREONINE-PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;positive regulation of cell motility#GO:2000147;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell motility#GO:2000145;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to nitrogen compound#GO:1901699;negative regulation of apoptotic process#GO:0043066;regulation of locomotion#GO:0040012;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of locomotion#GO:0040017;negative regulation of cellular process#GO:0048523;cellular response to insulin stimulus#GO:0032869;regulation of cell migration#GO:0030334 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>Akt/PKB#P01408;p53 pathway by glucose deprivation#P04397>Akt#P04641;p53 pathway feedback loops 2#P04398>AKT#P04665;Hypoxia response via HIF activation#P00030>AKT#P00819;FAS signaling pathway#P00020>ASK1#P00614;Angiogenesis#P00005>Akt#P00223;Endothelin signaling pathway#P00019>Akt#P00589;FGF signaling pathway#P00021>Akt#P00632;p53 pathway#P00059>Akt#P01486;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>AKT#P00894;Apoptosis signaling pathway#P00006>AKT#P00260;PI3 kinase pathway#P00048>PKB#P01179;EGF receptor signaling pathway#P00018>Akt#P00551 DROME|FlyBase=FBgn0033599|UniProtKB=A1Z8H3 A1Z8H3 Dmel\CG13223 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0033096|UniProtKB=Q7JZR2 Q7JZR2 Zip42C.1 PTHR11040:SF203 ZINC/IRON TRANSPORTER FI18611P1-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;cellular process#GO:0009987;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0052485|UniProtKB=Q8I941 Q8I941 CG2159 PTHR45824:SF6 GH16843P GH16843P phosphatidylinositol transfer activity#GO:0008526;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 DROME|FlyBase=FBgn0032329|UniProtKB=Q8SX32 Q8SX32 Art8 PTHR11006:SF122 PROTEIN ARGININE N-METHYLTRANSFERASE TYPE I PROTEIN ARGININE METHYLTRANSFERASE histone modifying activity#GO:0140993;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0053855|UniProtKB=Q4AB54 Q4AB54 His1:CG33861 PTHR11467:SF36 HISTONE H1 H1.010 LINKER HISTONE, CLUSTER MEMBER-RELATED chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of DNA recombination#GO:0000018;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0053129|UniProtKB=Q9VKM7 Q9VKM7 Tmem214 PTHR13448:SF0 TRANSMEMBRANE PROTEIN 214 TRANSMEMBRANE PROTEIN 214 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0032014|UniProtKB=Q9VLP9 Q9VLP9 CG7840 PTHR14624:SF0 DFG10 PROTEIN POLYPRENAL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0283535|UniProtKB=P54611 P54611 Vha26 PTHR45715:SF23 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED ATPASE H+ TRANSPORTING V1 SUBUNIT E1 ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495 DROME|FlyBase=FBgn0035793|UniProtKB=B7Z0D3 B7Z0D3 clone 2.45 PTHR15204:SF0 LARGE PROLINE-RICH PROTEIN BAG6 LARGE PROLINE-RICH PROTEIN BAG6 protein binding#GO:0005515;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0024232|UniProtKB=O61366 O61366 gprs PTHR24410:SF23 HL07962P-RELATED SERINE-ENRICHED PROTEIN defense/immunity protein#PC00090 DROME|FlyBase=FBgn0003023|UniProtKB=P10383 P10383 otu PTHR12419:SF115 OTU DOMAIN CONTAINING PROTEIN DEUBIQUITINASE OTU-RELATED catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 cysteine protease#PC00081 DROME|FlyBase=FBgn0023076|UniProtKB=O61735 O61735 Clk PTHR46055:SF3 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT DROME|FlyBase=FBgn0037543|UniProtKB=Q9VHW6 Q9VHW6 Dmel\CG10903 PTHR12734:SF0 METHYLTRANSFERASE-RELATED 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE rRNA methyltransferase activity#GO:0008649;rRNA (guanine) methyltransferase activity#GO:0016435;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;rRNA metabolic process#GO:0016072;intracellular transport#GO:0046907;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;nuclear export#GO:0051168;rRNA processing#GO:0006364;nuclear transport#GO:0051169;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;ribosome localization#GO:0033750;organelle localization#GO:0051640;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 DROME|FlyBase=FBgn0260454|UniProtKB=Q9VKP3 Q9VKP3 CG31722 PTHR11743:SF70 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL GH26960P-RELATED channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803 mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;intracellular transport#GO:0046907;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0010114|UniProtKB=Q09101 Q09101 hig PTHR19325:SF579 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING LOCOMOTION-RELATED PROTEIN HIKARU GENKI complement component#PC00078;defense/immunity protein#PC00090 DROME|FlyBase=FBgn0038889|UniProtKB=Q9VDA0 Q9VDA0 Fancm PTHR14025:SF20 FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER FANCONI ANEMIA GROUP M PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;four-way junction DNA binding#GO:0000400;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0003330|UniProtKB=Q9VB08 Q9VB08 Sce PTHR46076:SF3 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;chromatin binding#GO:0003682;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0010015|UniProtKB=P48456 P48456 CanA1 PTHR45673:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED binding#GO:0005488;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;calcineurin-mediated signaling#GO:0097720;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protein phosphatase#PC00195 Wnt signaling pathway#P00057>Calcineurin#P01446 DROME|FlyBase=FBgn0039915|UniProtKB=Q9V4E7 Q9V4E7 Gat PTHR11616:SF333 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;amino acid transport#GO:0006865 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 primary active transporter#PC00068 DROME|FlyBase=FBgn0260743|UniProtKB=Q9VGF7 Q9VGF7 GC1 PTHR45678:SF5 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0265991|UniProtKB=A1ZA47 A1ZA47 Zasp52 PTHR24214:SF38 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN ZASP-RELATED binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856 adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;actomyosin#GO:0042641;cell-cell junction#GO:0005911;supramolecular fiber#GO:0099512;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0260759|UniProtKB=Q9VAD5 Q9VAD5 CG7866 PTHR31800:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840 DROME|FlyBase=FBgn0052351|UniProtKB=Q9VSM7 Q9VSM7 S-Lap2 PTHR11963:SF25 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0037482|UniProtKB=Q9VI74 Q9VI74 CG10055 PTHR12967:SF0 PROTEIN SHQ1 HOMOLOG PROTEIN SHQ1 HOMOLOG cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033041|UniProtKB=Q9V9I2 Q9V9I2 Or42a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0053262|UniProtKB=Q7KUI9 Q7KUI9 Dmel\CG33262 PTHR21398:SF21 AGAP007094-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0033482|UniProtKB=A1Z843 A1Z843 Dmel\CG1371 PTHR23303:SF14 CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING BOS COMPLEX SUBUNIT NOMO1-RELATED intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0013811|UniProtKB=Q7KVA7 Q7KVA7 Dhc62B PTHR10676:SF255 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 12 catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777 sexual reproduction#GO:0019953;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;inner dynein arm assembly#GO:0036159;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;protein-containing complex assembly#GO:0065003;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;inner dynein arm#GO:0036156;membraneless organelle#GO:0043228;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;catalytic complex#GO:1902494;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0027526|UniProtKB=Q9XZ16 Q9XZ16 Ublcp1 PTHR48493:SF1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0037917|UniProtKB=Q9VGL8 Q9VGL8 wkd PTHR22957:SF352 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER WHACKED GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0051371|UniProtKB=Q8IMI4 Q8IMI4 CG15542 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;oxidoreductase complex#GO:1990204;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0043575|UniProtKB=Q9V4X2 Q9V4X2 PGRP-SC2 PTHR11022:SF75 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN SB1-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;peptidoglycan muralytic activity#GO:0061783;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0083961|UniProtKB=Q0E8T6 Q0E8T6 Dmel\CG34125 PTHR31638:SF3 DAZ-ASSOCIATED PROTEIN 2 DAZ-ASSOCIATED PROTEIN 2 DROME|FlyBase=FBgn0010774|UniProtKB=Q9V3E7 Q9V3E7 Ref1 PTHR19965:SF35 RNA AND EXPORT FACTOR BINDING PROTEIN THO COMPLEX SUBUNIT 4 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;localization#GO:0051179;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0069973|UniProtKB=Q6NNV7 Q6NNV7 FOHSDR PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0053144|UniProtKB=Q7JR34 Q7JR34 CG12339 PTHR11685:SF225 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144B protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0263232|UniProtKB=Q8IQK4 Q8IQK4 Nxf3 PTHR10662:SF22 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0010333|UniProtKB=P40792 P40792 Rac1 PTHR24072:SF411 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001 actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;axon guidance#GO:0007411;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;organelle organization#GO:0006996;cell projection assembly#GO:0030031;signal transduction#GO:0007165;cellular process#GO:0009987;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;cellular developmental process#GO:0048869;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cell communication#GO:0007154;regulation of cell motility#GO:2000145;supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;cortical cytoskeleton organization#GO:0030865;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of developmental process#GO:0050793;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;Rac protein signal transduction#GO:0016601;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;signaling#GO:0023052;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 G-protein#PC00020;small GTPase#PC00208 Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by netrin#P00009>Rac#P00366;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;Integrin signalling pathway#P00034>Rac#P00927;Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;T cell activation#P00053>rac#P01324;EGF receptor signaling pathway#P00018>Rac#P00564;FGF signaling pathway#P00021>Rac#P00645 DROME|FlyBase=FBgn0033092|UniProtKB=Q0E9N4 Q0E9N4 Rpp25 PTHR13516:SF30 RIBONUCLEASE P SUBUNIT P25 FI09323P nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 catalytic complex#GO:1902494;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;ribonucleoprotein complex#GO:1990904;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0013685|UniProtKB=P18933 P18933 mt:ND6 PTHR11435:SF1 NADH UBIQUINONE OXIDOREDUCTASE SUBUNIT ND6 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 DROME|FlyBase=FBgn0051643|UniProtKB=Q960W0 Q960W0 Dmel\CG31643 PTHR21228:SF74 FAST LEU-RICH DOMAIN-CONTAINING LD32258P nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;regulation of RNA stability#GO:0043487 membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233 RNA processing factor#PC00147 DROME|FlyBase=FBgn0085465|UniProtKB=A8JRE8 A8JRE8 Dmel\CG34436 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0010926|UniProtKB=Q9VEJ2 Q9VEJ2 l(3)07882 PTHR23183:SF0 NOP14 NUCLEOLAR PROTEIN 14 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039782|UniProtKB=Q0KHY7 Q0KHY7 Dmel\CG15539 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0029506|UniProtKB=Q7KJ73 Q7KJ73 Tsp42Ee PTHR19282:SF521 TETRASPANIN AT12771P-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0003720|UniProtKB=P18102 P18102 tll PTHR24083:SF189 NUCLEAR HORMONE RECEPTOR PROTEIN TAILLESS transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0039425|UniProtKB=Q9VBF5 Q9VBF5 Aldol PTHR11627:SF80 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 lyase#PC00144;aldolase#PC00044 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 DROME|FlyBase=FBgn0031016|UniProtKB=Q9VWI6 Q9VWI6 kek5 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0033337|UniProtKB=A0A0B4KEH1 A0A0B4KEH1 FBXL9 PTHR13318:SF50 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 7 DROME|FlyBase=FBgn0266667|UniProtKB=Q9VSJ8 Q9VSJ8 Exo70 PTHR12542:SF41 EXOCYST COMPLEX PROTEIN EXO70 EXOCYST COMPLEX COMPONENT 7 transport#GO:0006810;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0262115|UniProtKB=Q8SYS7 Q8SYS7 CG17683 PTHR11615:SF372 NITRATE, FORMATE, IRON DEHYDROGENASE CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR CG17683-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037121|UniProtKB=Q9VNZ3 Q9VNZ3 Polr2H PTHR10917:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 DROME|FlyBase=FBgn0030506|UniProtKB=Q9VYA5 Q9VYA5 DNAlig4 PTHR45997:SF3 DNA LIGASE 4 DNA LIGASE 4 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleic acid binding#GO:0003676;ion binding#GO:0043167;DNA binding#GO:0003677;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;ligase activity#GO:0016874;catalytic activity, acting on DNA#GO:0140097;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 DNA repair complex#GO:1990391;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0038046|UniProtKB=Q9VG73 Q9VG73 CG5641 PTHR46447:SF1 INTERLEUKIN ENHANCER-BINDING FACTOR INTERLEUKIN ENHANCER-BINDING FACTOR 2 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 transcription cofactor#PC00217 DROME|FlyBase=FBgn0026259|UniProtKB=Q9VZP5 Q9VZP5 eIF5B PTHR43381:SF4 TRANSLATION INITIATION FACTOR IF-2-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 5B translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 DROME|FlyBase=FBgn0030798|UniProtKB=E1JJN4 E1JJN4 Dmel\CG13003 PTHR37853:SF1 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0037363|UniProtKB=Q7KTS2 Q7KTS2 Atg17 PTHR13222:SF5 RB1-INDUCIBLE COILED-COIL RB1-INDUCIBLE COILED-COIL PROTEIN 1 binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;vacuole organization#GO:0007033;reticulophagy#GO:0061709;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;phagophore assembly site#GO:0000407;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032066|UniProtKB=Q9VLI2 Q9VLI2 LManIII PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764 glycosidase#PC00110;hydrolase#PC00121 DROME|FlyBase=FBgn0270927|UniProtKB=Q9V9T9 Q9V9T9 betaGlu PTHR10066:SF70 BETA-GLUCURONIDASE BETA-GLUCURONIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824;carbohydrate binding#GO:0030246;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0029147|UniProtKB=Q9W288 Q9W288 NtR PTHR18945:SF430 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-LIKE 2-RELATED gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261 metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;signaling receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 DROME|FlyBase=FBgn0035443|UniProtKB=Q8IRD1 Q8IRD1 Dmel\CG12010 PTHR23077:SF117 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG B pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0004432|UniProtKB=P25007 P25007 Cyp1 PTHR11071:SF582 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 DROME|FlyBase=FBgn0032135|UniProtKB=Q9VLA1 Q9VLA1 GlcAT-S PTHR10896:SF51 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE S UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;hexosyltransferase activity#GO:0016758 proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0038334|UniProtKB=Q9VF68 Q9VF68 h-cup PTHR12186:SF2 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 HOMOLOG DROME|FlyBase=FBgn0051269|UniProtKB=Q8INA1 Q8INA1 CG5233 PTHR24260:SF138 AT07769P-RELATED IP10340P-RELATED DROME|FlyBase=FBgn0284084|UniProtKB=P09615 P09615 wg PTHR12027:SF91 WNT RELATED PROTO-ONCOGENE WNT-1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;system development#GO:0048731;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 DROME|FlyBase=FBgn0039016|UniProtKB=Q9VCU9 Q9VCU9 Dcr-1 PTHR14950:SF82 DICER-RELATED ENDORIBONUCLEASE DICER DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity, acting on DNA#GO:0140097;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788 DNA catabolic process#GO:0006308;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;siRNA processing#GO:0030422;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;apoptotic DNA fragmentation#GO:0006309;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;cell death#GO:0008219;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555 DROME|FlyBase=FBgn0038769|UniProtKB=Q8T0D9 Q8T0D9 Regnase-1 PTHR12876:SF35 N4BP1-RELATED LD08718P-RELATED catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 endoribonuclease#PC00094 DROME|FlyBase=FBgn0034651|UniProtKB=Q8T965 Q8T965 Dmel\CG15676 PTHR12409:SF0 PREFOLDIN SUBUNIT 3 PREFOLDIN SUBUNIT 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;protein metabolic process#GO:0019538;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chaperone#PC00072 DROME|FlyBase=FBgn0045442|UniProtKB=P83119 P83119 mthl12 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0019925|UniProtKB=O18405 O18405 Surf4 PTHR23427:SF1 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|FlyBase=FBgn0061360|UniProtKB=A1Z933 A1Z933 CG8810 PTHR12735:SF27 BOLA-LIKE PROTEIN-RELATED BOLA-LIKE PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0026398|UniProtKB=P81909 P81909 Or22a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0267383|UniProtKB=Q9VFR8 Q9VFR8 Ubc87F PTHR24067:SF3 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 DROME|FlyBase=FBgn0026386|UniProtKB=P81921 P81921 Or47a PTHR21137:SF43 ODORANT RECEPTOR ODORANT RECEPTOR 47A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0033624|UniProtKB=Q7JRC0 Q7JRC0 BcDNA:RH17411 PTHR13177:SF4 DEATH-ASSOCIATED PROTEIN 1 GEO09647P1 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 cell communication#GO:0007154;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of translation#GO:0017148;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165 DROME|FlyBase=FBgn0037643|UniProtKB=Q95U38 Q95U38 ScsbetaA PTHR11815:SF1 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;tricarboxylic acid cycle#GO:0006099;organophosphate metabolic process#GO:0019637 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142 DROME|FlyBase=FBgn0288846|UniProtKB=Q9VHW4 Q9VHW4 unc-45 PTHR45994:SF1 FI21225P1 FI21225P1 Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0031694|UniProtKB=Q9VMS8 Q9VMS8 Cyp4ac2 PTHR24291:SF105 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4P1-RELATED oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0035761|UniProtKB=Q9VS45 Q9VS45 RhoGEF4 PTHR12673:SF159 FACIOGENITAL DYSPLASIA PROTEIN LD03170P guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 DROME|FlyBase=FBgn0015829|UniProtKB=O96881 O96881 TfIIEbeta PTHR12716:SF8 TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;transcription factor binding#GO:0008134;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEbeta#P00659;Transcription regulation by bZIP transcription factor#P00055>TFIIEbeta#P01386;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 DROME|FlyBase=FBgn0038740|UniProtKB=A0A0B4KGI0 A0A0B4KGI0 Mrp5 PTHR24223:SF448 ATP-BINDING CASSETTE SUB-FAMILY C FI20146P1-RELATED localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0003435|UniProtKB=A0A0B4K7I2 A0A0B4K7I2 sm PTHR15592:SF18 MATRIN 3/NUCLEAR PROTEIN 220-RELATED SMOOTH, ISOFORM T RNA processing factor#PC00147 DROME|FlyBase=FBgn0011225|UniProtKB=Q01989 Q01989 jar PTHR13140:SF870 MYOSIN MYOSIN HEAVY CHAIN 95F isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based movement#GO:0030048;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0051776|UniProtKB=Q8IA43 Q8IA43 pgant10 PTHR11675:SF134 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0028343|UniProtKB=Q8MQX9 Q8MQX9 Ankle2 PTHR12349:SF4 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488;protein phosphatase binding#GO:0019903;protein binding#GO:0005515 membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;nuclear envelope organization#GO:0006998;mitotic cell cycle process#GO:1903047;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;membrane assembly#GO:0071709;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle fission#GO:0048285;nuclear division#GO:0000280 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0003345|UniProtKB=P30052 P30052 sd PTHR11834:SF0 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED PROTEIN SCALLOPED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0025626|UniProtKB=Q9W531 Q9W531 EG:22E5.7 PTHR14195:SF2 G PATCH DOMAIN CONTAINING PROTEIN 2 GH10944P intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0038851|UniProtKB=Q9VDF1 Q9VDF1 dmrt93B PTHR12322:SF121 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX-MAB RELATED 93B RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0265042|UniProtKB=A0A0B4KH86 A0A0B4KH86 Irk1 PTHR11767:SF102 INWARD RECTIFIER POTASSIUM CHANNEL INWARDLY RECTIFYING POTASSIUM CHANNEL 1, ISOFORM F-RELATED voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267 cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 DROME|FlyBase=FBgn0038951|UniProtKB=Q9VD25 Q9VD25 Polr3F PTHR12780:SF1 RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6 protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0032298|UniProtKB=Q9VKQ3 Q9VKQ3 CG6724 PTHR19855:SF11 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 HOMOLOG DROME|FlyBase=FBgn0020443|UniProtKB=Q9VK85 Q9VK85 eRF3 PTHR23115:SF36 TRANSLATION FACTOR G1 TO S PHASE TRANSITION 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translational termination#GO:0006415;translation#GO:0006412;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation factor#PC00223 DROME|FlyBase=FBgn0036105|UniProtKB=Q9VTC2 Q9VTC2 Blos4 PTHR16230:SF6 CAPPUCCINO BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 4 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular pigmentation#GO:0033059;melanosome organization#GO:0032438;pigmentation#GO:0043473;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083 DROME|FlyBase=FBgn0034688|UniProtKB=Q9W299 Q9W299 Dmel\CG11474 PTHR12260:SF6 DAMAGE-CONTROL PHOSPHATASE ARMT1 DAMAGE-CONTROL PHOSPHATASE 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stress#GO:0006950;response to stimulus#GO:0050896 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0264954|UniProtKB=A0A4D6K5G3 A0A4D6K5G3 fd3F PTHR11829:SF142 FORKHEAD BOX PROTEIN FORK-HEAD DOMAIN-CONTAINING PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0036257|UniProtKB=Q9VTU3 Q9VTU3 RhoGAP68F PTHR45808:SF23 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 68F enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;regulation of transport#GO:0051049;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174;VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520 DROME|FlyBase=FBgn0051809|UniProtKB=Q8INZ8 Q8INZ8 Dmel\CG31809 PTHR43899:SF9 RH59310P MIP25013P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0025802|UniProtKB=Q9VGH9 Q9VGH9 Sbf PTHR10807:SF109 MYOTUBULARIN-RELATED SET DOMAIN BINDING FACTOR, ISOFORM A molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;lipid modification#GO:0030258;dephosphorylation#GO:0016311;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 phosphatase#PC00181 DROME|FlyBase=FBgn0263850|UniProtKB=A0A0B4KEV6 A0A0B4KEV6 Dmel\CG43711 PTHR23198:SF29 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN DDB_G0274915 binding#GO:0005488;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;RNA binding#GO:0003723 nucleocytoplasmic transport#GO:0006913;organelle localization#GO:0051640;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;telomere localization#GO:0034397;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;telomere tethering at nuclear periphery#GO:0034398;protein transport#GO:0015031;protein import into nucleus#GO:0006606;cellular localization#GO:0051641;cellular component organization#GO:0016043;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome localization#GO:0050000 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 DROME|FlyBase=FBgn0033484|UniProtKB=A1Z847 A1Z847 Dmel\CG2269 PTHR37687:SF1 AGAP006772-PA SERINE_THREONINE-PROTEIN KINASE KINX ISOFORM X1-RELATED DROME|FlyBase=FBgn0040651|UniProtKB=Q9VR93 Q9VR93 CG15458 PTHR34038:SF1 ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT K, MITOCHONDRIAL proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 DROME|FlyBase=FBgn0000560|UniProtKB=P15370 P15370 eg PTHR48092:SF9 KNIRPS-RELATED PROTEIN-RELATED KNIRPS-RELATED PROTEIN-RELATED nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0041225|UniProtKB=Q8IMZ5 Q8IMZ5 Gr94a PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034391|UniProtKB=A1ZBD8 A1ZBD8 Dmel\CG15080 PTHR10900:SF126 PERIOSTIN-RELATED MUCIN-5AC-RELATED binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0050018|UniProtKB=V9H0I1 V9H0I1 mthl13 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0285912|UniProtKB=Q9VC02 Q9VC02 mah PTHR48017:SF298 OS05G0424000 PROTEIN-RELATED MAHOGANY DROME|FlyBase=FBgn0262614|UniProtKB=A0A0B4K6Y7 A0A0B4K6Y7 pyd PTHR13865:SF28 TIGHT JUNCTION PROTEIN POLYCHAETOID, ISOFORM O protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell junction organization#GO:0045216;cell adhesion#GO:0007155;protein localization to cell junction#GO:1902414;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;macromolecule localization#GO:0033036;cell junction organization#GO:0034330 anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 cell junction protein#PC00070;tight junction#PC00214 DROME|FlyBase=FBgn0038640|UniProtKB=E2QCZ5 E2QCZ5 Dmel\CG7706 PTHR23308:SF66 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 KANADAPTIN molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0030998|UniProtKB=Q9VWK4 Q9VWK4 Dmel\CG14195 PTHR11360:SF260 MONOCARBOXYLATE TRANSPORTER IP12869P monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0036330|UniProtKB=Q9VU31 Q9VU31 CG11263 PTHR46628:SF2 PIRNA BIOGENESIS PROTEIN EXD1 PROTEIN EXD1 HOMOLOG protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0062412|UniProtKB=Q9VHS6 Q9VHS6 Ctr1B PTHR12483:SF115 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS COPPER TRANSPORT PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transition metal ion transport#GO:0000041;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;copper ion transmembrane transport#GO:0035434;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0001994|UniProtKB=Q9V406 Q9V406 crp PTHR15741:SF27 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR AP-4 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0037763|UniProtKB=Q9VH57 Q9VH57 Dmel\CG16904 PTHR11157:SF116 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 DROME|Gene_ORFName=Dmel_CG46520|UniProtKB=A0ACD4DAY3 A0ACD4DAY3 CG46520 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 DROME|FlyBase=FBgn0037696|UniProtKB=Q9VHD3 Q9VHD3 GstZ1 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859 sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;glutathione metabolic process#GO:0006749;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 isomerase#PC00135 DROME|FlyBase=FBgn0054057|UniProtKB=Q2PE08 Q2PE08 CG13904 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 DROME|FlyBase=FBgn0015282|UniProtKB=P48601 P48601 Rpt2 PTHR23073:SF24 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 isomerase activity#GO:0016853;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0031111|UniProtKB=Q9VR96 Q9VR96 Obp19c PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0034274|UniProtKB=Q1RKU8 Q1RKU8 Dmel\CG10931 PTHR22847:SF751 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase II#GO:0006366;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;DNA-templated transcription initiation#GO:0006352;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604 acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;chromosome#GO:0005694;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0051164|UniProtKB=Q8IN10 Q8IN10 Ir94a PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0032171|UniProtKB=Q9VL58 Q9VL58 Dmel\CG5846 PTHR24124:SF15 ANKYRIN REPEAT FAMILY A LP07441P regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0015777|UniProtKB=Q24048 Q24048 nrv2 PTHR11523:SF46 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0001250|UniProtKB=P12080 P12080 if PTHR23220:SF133 INTEGRIN ALPHA INTEGRIN ALPHA-PS2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane#GO:0016020;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 DROME|FlyBase=FBgn0032884|UniProtKB=Q9VIJ5 Q9VIJ5 Pomp PTHR12828:SF3 PROTEASOME MATURATION PROTEIN UMP1 PROTEASOME MATURATION PROTEIN cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0037387|UniProtKB=Q7JVN6 Q7JVN6 Dmel\CG1213 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0263392|UniProtKB=M9NEY8 M9NEY8 Tet PTHR23358:SF6 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0031627|UniProtKB=Q9VR25 Q9VR25 fipi PTHR12231:SF259 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN FACTOR OF INTERPULSE INTERVAL-RELATED binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;protein binding#GO:0005515 cellular process#GO:0009987;synapse organization#GO:0050808;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell junction#GO:0030054 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0003742|UniProtKB=P19018 P19018 tra2 PTHR48034:SF37 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 SEX-DETERMINING PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031747|UniProtKB=Q9VML5 Q9VML5 Dmel\CG9021 PTHR21163:SF0 PROTEIN G12 GH08205P-RELATED DROME|FlyBase=FBgn0004396|UniProtKB=P29747 P29747 CrebA PTHR46004:SF3 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 DROME|FlyBase=FBgn0034723|UniProtKB=Q9W259 Q9W259 13506 PTHR45080:SF38 CONTACTIN 5 FI23916P1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;synapse organization#GO:0050808;cell junction organization#GO:0034330;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987 cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axon#GO:0030424 DROME|FlyBase=FBgn0000520|UniProtKB=Q9W4V9 Q9W4V9 dwg PTHR24384:SF189 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0039969|UniProtKB=B7YZT2 B7YZT2 Fis1 PTHR13247:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 MITOCHONDRIAL FISSION 1 PROTEIN binding#GO:0005488;lipid binding#GO:0008289 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266;peroxisome organization#GO:0007031;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;microbody#GO:0042579;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;peroxisomal membrane#GO:0005778;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0004862|UniProtKB=P22809 P22809 bap PTHR24340:SF73 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN BAGPIPE-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0035756|UniProtKB=Q9VS41 Q9VS41 unc-13-4A PTHR45999:SF4 UNC-13-4A, ISOFORM B UNC-13-4A, ISOFORM B DROME|FlyBase=FBgn0024509|UniProtKB=Q9V3J4 Q9V3J4 Sec13 PTHR11024:SF21 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER PROTEIN SEC13 HOMOLOG regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;organelle organization#GO:0006996;vesicle-mediated transport#GO:0016192;COPII-coated vesicle budding#GO:0090114;nucleocytoplasmic transport#GO:0006913;positive regulation of TOR signaling#GO:0032008;nuclear transport#GO:0051169;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;positive regulation of intracellular signal transduction#GO:1902533;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle budding from membrane#GO:0006900;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;regulation of signal transduction#GO:0009966;membrane organization#GO:0061024;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 nuclear pore#GO:0005643;bounding membrane of organelle#GO:0098588;nuclear protein-containing complex#GO:0140513;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090;nucleus#GO:0005634;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;nuclear pore outer ring#GO:0031080;vesicle#GO:0031982;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 DROME|FlyBase=FBgn0265623|UniProtKB=P25172 P25172 Su(z)2 PTHR10825:SF29 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transferase complex#GO:1990234;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0020887|UniProtKB=Q9NJG9 Q9NJG9 Su(z)12 PTHR22597:SF0 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SUZ12 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;constitutive heterochromatin formation#GO:0140719;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629 nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0034076|UniProtKB=A1ZA97 A1ZA97 Jhedup PTHR11559:SF428 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE esterase#PC00097 DROME|FlyBase=FBgn0030004|UniProtKB=Q9W3J8 Q9W3J8 CG10958 PTHR21625:SF1 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX PROTEIN 1 cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium or flagellum-dependent cell motility#GO:0001539;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0262467|UniProtKB=Q9VMX4 Q9VMX4 Scox PTHR12151:SF5 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER AT19154P cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535 oxidase#PC00175;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0052944|UniProtKB=Q9VN23 Q9VN23 CG10532 PTHR24356:SF422 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0050381|UniProtKB=A0A0B4LES9 A0A0B4LES9 PIG-X PTHR28650:SF1 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, STABILIZING SUBUNIT DROME|FlyBase=FBgn0039286|UniProtKB=Q9VBW6 Q9VBW6 dan PTHR33215:SF13 PROTEIN DISTAL ANTENNA PROTEIN DISTAL ANTENNA DROME|FlyBase=FBgn0010651|UniProtKB=Q8MRP7 Q8MRP7 MFS14 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034999|UniProtKB=Q8SXR7 Q8SXR7 Fatp3 PTHR43107:SF31 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN VERY LONG-CHAIN FATTY ACID TRANSPORT PROTEIN ligase activity, forming carbon-sulfur bonds#GO:0016877;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;monocarboxylic acid transmembrane transporter activity#GO:0008028;catalytic activity#GO:0003824;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;lipid transport#GO:0006869;carboxylic acid transport#GO:0046942;lipid metabolic process#GO:0006629;transport#GO:0006810;organic acid transport#GO:0015849;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;import into cell#GO:0098657;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179 organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0265082|UniProtKB=A8JQT5 A8JQT5 Cdep PTHR45858:SF5 FERM DOMAIN CONTAINING PROTEIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 DROME|FlyBase=FBgn0034507|UniProtKB=A1ZBU1 A1ZBU1 SP82 PTHR24276:SF97 POLYSERASE-RELATED GH13245P2-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0000504|UniProtKB=P23023 P23023 dsx PTHR12322:SF129 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT PROTEIN DOUBLESEX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;reproductive process#GO:0022414;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0011648|UniProtKB=P42003 P42003 Mad PTHR13703:SF61 SMAD PROTEIN MOTHERS AGAINST DPP sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to growth factor stimulus#GO:0071363;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 SCW signaling pathway#P06216>MED#P06323;DPP signaling pathway#P06213>MAD#P06288;GBB signaling pathway#P06214>MED#P06299;MYO signaling pathway#P06215>MED#P06311;DPP signaling pathway#P06213>MED#P06279;Wnt signaling pathway#P00057>Smad4#P01455;DPP-SCW signaling pathway#P06212>MAD#P06271;DPP-SCW signaling pathway#P06212>MED#P06265;SCW signaling pathway#P06216>MAD#P06331;ALP23B signaling pathway#P06209>MED#P06221;Activin beta signaling pathway#P06210>MED#P06233;GBB signaling pathway#P06214>MAD#P06305;TGF-beta signaling pathway#P00052>RSmads#P01292;BMP/activin signaling pathway-drosophila#P06211>R-Smad#P06245 DROME|FlyBase=FBgn0030559|UniProtKB=Q9VY41 Q9VY41 Dmel\CG13404 PTHR13411:SF6 PLASMINOGEN RECEPTOR (KT) PLASMINOGEN RECEPTOR (KT) DROME|FlyBase=FBgn0035959|UniProtKB=Q9VST7 Q9VST7 Dmel\CG4911 PTHR20933:SF3 F-BOX ONLY PROTEIN 33 F-BOX ONLY PROTEIN 33 regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399 DROME|FlyBase=FBgn0038690|UniProtKB=Q9V3Q7 Q9V3Q7 JYbeta2 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;import across plasma membrane#GO:0098739;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0263352|UniProtKB=B7Z0E2 B7Z0E2 Unr PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 protein-RNA adaptor activity#GO:0140517;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of RNA stability#GO:0043487;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DROME|FlyBase=FBgn0034803|UniProtKB=Q9W1W9 Q9W1W9 CG9849 PTHR22702:SF1 PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0030746|UniProtKB=Q9VXG7 Q9VXG7 DmCG9981 PTHR24092:SF230 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657 cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0040107|UniProtKB=Q9VPS2 Q9VPS2 lectin-21Ca PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN binding#GO:0005488;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0052698|UniProtKB=Q9W316 Q9W316 CARPB PTHR18952:SF283 CARBONIC ANHYDRASE CARBONIC ANHYDRASE XB-RELATED metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0017590|UniProtKB=Q9VCT4 Q9VCT4 klg PTHR45080:SF38 CONTACTIN 5 FI23916P1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;cell junction organization#GO:0034330;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840 cell body#GO:0044297;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;neuronal cell body#GO:0043025;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424 DROME|FlyBase=FBgn0025640|UniProtKB=O77425 O77425 Dmel\CG13369 PTHR10584:SF166 SUGAR KINASE RIBOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 kinase#PC00137;carbohydrate kinase#PC00065 DROME|FlyBase=FBgn0038055|UniProtKB=Q9VG62 Q9VG62 trus PTHR46421:SF1 PROGRAMMED CELL DEATH PROTEIN 2-LIKE US5 ASSEMBLY CHAPERONE PDCD2L programmed cell death#GO:0012501;cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915 DROME|FlyBase=FBgn0037765|UniProtKB=Q9VH55 Q9VH55 CT26802 PTHR11157:SF116 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0033485|UniProtKB=Q7K1Q7 Q7K1Q7 RpLP0-like PTHR45841:SF1 MRNA TURNOVER PROTEIN 4 MRTO4 MRNA TURNOVER PROTEIN 4 HOMOLOG regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;rRNA processing#GO:0006364;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0052528|UniProtKB=Q9VWD0 Q9VWD0 parvin PTHR12114:SF4 PARVIN GH23568P cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin and actin related protein#PC00039;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0024491|UniProtKB=Q9VEX9 Q9VEX9 Bin1 PTHR13082:SF0 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 Hedgehog signaling pathway#P00025>Sap18#P00697 DROME|FlyBase=FBgn0054041|UniProtKB=Q2PDP5 Q2PDP5 Dmel\CG34041 PTHR10869:SF236 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030103|UniProtKB=Q9W372 Q9W372 Obp8a PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0034838|UniProtKB=Q9W1T0 Q9W1T0 Dmel\CG12782 PTHR10971:SF11 MRNA EXPORT FACTOR AND BUB3 MRNA EXPORT FACTOR RAE1 ubiquitin binding#GO:0043130;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;protein binding#GO:0005515 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA transport#GO:0050658;RNA localization#GO:0006403;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039790|UniProtKB=Q9VA53 Q9VA53 Dmel\CG2246 PTHR10210:SF53 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER GH23275P transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 DROME|FlyBase=FBgn0020412|UniProtKB=Q9V3I5 Q9V3I5 JIL-1 PTHR24351:SF289 RIBOSOMAL PROTEIN S6 KINASE CHROMOSOMAL SERINE_THREONINE-PROTEIN KINASE JIL-1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;TOR signaling#GO:0031929;regulation of nucleobase-containing compound metabolic process#GO:0019219 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 DROME|FlyBase=FBgn0032845|UniProtKB=Q9VIP3 Q9VIP3 38B.13 PTHR13593:SF113 FAMILY NOT NAMED PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C X DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 DROME|FlyBase=FBgn0030468|UniProtKB=Q9VYE9 Q9VYE9 Dmel\CG1622 PTHR23142:SF2 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38B RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011 DROME|FlyBase=FBgn0000414|UniProtKB=P98081 P98081 Dab PTHR11232:SF47 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN DISABLED signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179 neuron projection#GO:0043005;cytosol#GO:0005829;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0015399|UniProtKB=Q9VK54 Q9VK54 kek1 PTHR24366:SF140 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS KEKKON 1, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0034013|UniProtKB=Q95TU8 Q95TU8 unc-5 PTHR12582:SF50 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC-5 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 neuron differentiation#GO:0030182;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 DROME|FlyBase=FBgn0029170|UniProtKB=Q9VB86 Q9VB86 TwdlT PTHR31927:SF16 FI07246P-RELATED-RELATED LP07342P structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0024689|UniProtKB=Q9VJD3 Q9VJD3 fws PTHR13228:SF3 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;intra-Golgi vesicle-mediated transport#GO:0006891 COG complex#GO:0017119;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0053092|UniProtKB=Q8T0Q8 Q8T0Q8 P5CDh2 PTHR42862:SF1 DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytoplasmic side of plasma membrane#GO:0009898;organelle lumen#GO:0043233 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 DROME|FlyBase=FBgn0002542|UniProtKB=P34739 P34739 lds PTHR45626:SF50 TRANSCRIPTION TERMINATION FACTOR 2-RELATED TRANSCRIPTION TERMINATION FACTOR 2 ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 DROME|FlyBase=FBgn0039175|UniProtKB=Q9VCA5 Q9VCA5 beta-PheRS PTHR10947:SF0 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 PHENYLALANINE--TRNA LIGASE BETA SUBUNIT catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0030671|UniProtKB=Q9VXR6 Q9VXR6 Hap40 PTHR16797:SF4 FACTOR VIII-ASSOCIATED GENE 1 40-KDA HUNTINGTIN-ASSOCIATED PROTEIN establishment of vesicle localization#GO:0051650;establishment of organelle localization#GO:0051656;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;vesicle cytoskeletal trafficking#GO:0099518;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;organelle localization#GO:0051640 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 DROME|FlyBase=FBgn0030385|UniProtKB=Q9VYN4 Q9VYN4 Ir11a PTHR42643:SF52 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 11A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0026147|UniProtKB=Q8IPB2 Q8IPB2 TTLL4A PTHR12241:SF162 TUBULIN POLYGLUTAMYLASE TUBULIN MONOGLUTAMYLASE TTLL4 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037659|UniProtKB=Q9VHH9 Q9VHH9 Kdm2 PTHR23123:SF21 PHD/F-BOX CONTAINING PROTEIN JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 1 histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0000579|UniProtKB=P15007 P15007 Eno PTHR11902:SF1 ENOLASE ENOLASE hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;phosphopyruvate hydratase activity#GO:0004634;catalytic activity#GO:0003824 glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;lyase#PC00144 Glycolysis#P00024>Enolase#P00678 DROME|FlyBase=FBgn0052797|UniProtKB=Q8IRW0 Q8IRW0 Dmel\CG32797 PTHR15405:SF0 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR AAQUETZALLI, ISOFORM A intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0000279|UniProtKB=O16829 O16829 CecC PTHR38329:SF1 CECROPIN-A1-RELATED CECROPIN-A1-RELATED defense response to Gram-positive bacterium#GO:0050830;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to external stimulus#GO:0009605;defense response#GO:0006952;antibacterial humoral response#GO:0019731 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0010408|UniProtKB=P55935 P55935 RpS9 PTHR11831:SF5 30S 40S RIBOSOMAL PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN US4 RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0260747|UniProtKB=Q9VX77 Q9VX77 Chchd2 PTHR13523:SF2 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 mitochondrion#GO:0005739;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0028838|UniProtKB=Q9VJR9 Q9VJR9 CSN1a PTHR14145:SF2 26S PROTESOME SUBUNIT 6 COP9 SIGNALOSOME COMPLEX SUBUNIT 1 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;regulation of protein stability#GO:0031647;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0260741|UniProtKB=Q9VGG0 Q9VGG0 Dmel\CG3281 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0033792|UniProtKB=Q7JY04 Q7JY04 Dmel\CG13325 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0034195|UniProtKB=Q4V3G2 Q4V3G2 Spn53F PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0038897|UniProtKB=Q9VD87 Q9VD87 Dmel\CG5849 PTHR11533:SF304 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006 peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0263032|UniProtKB=A0A0B4K829 A0A0B4K829 CG30459 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;membrane organization#GO:0061024 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle membrane contact site#GO:0044232;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743 DROME|FlyBase=FBgn0085345|UniProtKB=A1A6X9 A1A6X9 Dmel\CG34316 PTHR11008:SF43 PROTEIN TAKEOUT-LIKE PROTEIN IP17226P rhythmic process#GO:0048511;circadian rhythm#GO:0007623 DROME|FlyBase=FBgn0086691|UniProtKB=Q9V3W0 Q9V3W0 UK114 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;catalytic activity#GO:0003824 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 DROME|FlyBase=FBgn0010473|UniProtKB=Q967D7 Q967D7 tutl PTHR10075:SF92 BASIGIN RELATED PROTEIN TURTLE cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0259721|UniProtKB=B7Z0J4 B7Z0J4 CG9288 PTHR22977:SF1 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0040339|UniProtKB=Q9V439 Q9V439 MED22 PTHR12434:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0029133|UniProtKB=Q9V3P3 Q9V3P3 REG PTHR10660:SF2 PROTEASOME REGULATOR PA28 LD45860P enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of protein catabolic process#GO:0042176;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of mitotic cell cycle#GO:0007346;regulation of catabolic process#GO:0009894 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 DROME|FlyBase=FBgn0000147|UniProtKB=Q9VGF9 Q9VGF9 aurA PTHR24350:SF34 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049 supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0013750|UniProtKB=P40946 P40946 Arf6 PTHR11711:SF322 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020 Integrin signalling pathway#P00034>Arf6#P00919;Huntington disease#P00029>ARF#P00786 DROME|FlyBase=FBgn0037683|UniProtKB=Q9VHF2 Q9VHF2 CG18473 PTHR10819:SF3 PHOSPHOTRIESTERASE-RELATED N-ACETYLTAURINE HYDROLASE esterase#PC00097;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0053177|UniProtKB=Q86B54 Q86B54 Dmel\CG33177 PTHR10689:SF6 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039030|UniProtKB=Q9VCT3 Q9VCT3 Dmel\CG6660 PTHR11157:SF116 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0001180|UniProtKB=P05084 P05084 hb PTHR24392:SF62 ZINC FINGER PROTEIN PROTEIN CHARLATAN-RELATED DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0288700|UniProtKB=Q2MGK8 Q2MGK8 stg1 PTHR12107:SF0 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT STARGAZIN-LIKE PROTEIN monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated calcium channel activity#GO:0005245;channel regulator activity#GO:0016247;channel activity#GO:0015267;transporter regulator activity#GO:0141108 biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transmission of nerve impulse#GO:0019226;system process#GO:0003008;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;localization#GO:0051179;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;localization within membrane#GO:0051668;nervous system process#GO:0050877;regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806 organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 voltage-gated ion channel#PC00241;transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0004666|UniProtKB=P05709 P05709 sim PTHR23043:SF36 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PROTEIN SINGLE-MINDED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0037427|UniProtKB=A0A0B4KGL7 A0A0B4KGL7 Osi17 PTHR21879:SF4 FI03362P-RELATED-RELATED OSIRIS 17, ISOFORM C membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0010350|UniProtKB=P56079 P56079 Cds PTHR13773:SF8 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC transferase#PC00220 DROME|FlyBase=FBgn0033954|UniProtKB=A1Z9T6 A1Z9T6 bs33f06.y1 PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0037108|UniProtKB=Q9VP06 Q9VP06 Alg11 PTHR45919:SF1 GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0031141|UniProtKB=Q9VRD1 Q9VRD1 Dmel\CG1304 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0031655|UniProtKB=Q9VMX6 Q9VMX6 Marcal1 PTHR45766:SF6 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER SNF2 RELATED CHROMATIN REMODELING ANNEALING HELICASE 1 binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 DROME|FlyBase=FBgn0004647|UniProtKB=P07207 P07207 N PTHR22804:SF57 AGGRECAN/VERSICAN PROTEOGLYCAN NEUROGENIC LOCUS NOTCH PROTEIN extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Angiogenesis#P00005>Notch#P00255 DROME|FlyBase=FBgn0037365|UniProtKB=Q9VNG7 Q9VNG7 Dmel\CG2104 PTHR10012:SF0 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR protein phosphatase regulator activity#GO:0019888;cis-trans isomerase activity#GO:0016859;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;phosphatase activator activity#GO:0019211;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;phosphatase regulator activity#GO:0019208;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 phosphatase activator#PC00182 DROME|FlyBase=FBgn0038469|UniProtKB=Q9VEP3 Q9VEP3 Dmel\CG4009 PTHR11475:SF86 OXIDASE/PEROXIDASE PEROXIDASE catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0000337|UniProtKB=A1Z746 A1Z746 cn PTHR46028:SF2 KYNURENINE 3-MONOOXYGENASE KYNURENINE 3-MONOOXYGENASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0051907|UniProtKB=Q8IPI4 Q8IPI4 Mst27D PTHR10623:SF6 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER EB1, ISOFORM F-RELATED protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 intracellular protein localization#GO:0008104;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;spindle assembly#GO:0051225;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0039296|UniProtKB=Q9VBV5 Q9VBV5 Sil1 PTHR19316:SF35 PROTEIN FOLDING REGULATOR NUCLEOTIDE EXCHANGE FACTOR SIL1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0013753|UniProtKB=Q24040 Q24040 Bgb PTHR10276:SF3 CORE-BINDING FACTOR, BETA SUBUNIT CORE-BINDING FACTOR SUBUNIT BETA DNA binding#GO:0003677;transcription coactivator activity#GO:0003713;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0003863|UniProtKB=P04814 P04814 alphaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0263705|UniProtKB=Q0KHU0 Q0KHU0 Myo10A PTHR13140:SF709 MYOSIN UNCONVENTIONAL MYOSIN-XV microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 actin-based cell projection#GO:0098858;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0028523|UniProtKB=Q7KT58 Q7KT58 CT18477 PTHR46473:SF23 GH08155P GH08155P DROME|FlyBase=FBgn0039044|UniProtKB=Q8IMZ4 Q8IMZ4 p53 PTHR11447:SF16 CELLULAR TUMOR ANTIGEN P53 P53, ISOFORM B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981;positive regulation of macromolecule metabolic process#GO:0010604;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 P53-like transcription factor#PC00253;gene-specific transcriptional regulator#PC00264 Huntington disease#P00029>p53#P00797 DROME|FlyBase=FBgn0033842|UniProtKB=Q7K284 Q7K284 cbc PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 DROME|FlyBase=FBgn0039507|UniProtKB=Q9VB49 Q9VB49 mrt PTHR31802:SF54 32 KDA HEAT SHOCK PROTEIN-RELATED MARTIK, ISOFORM A-RELATED organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038504|UniProtKB=Q9VEK6 Q9VEK6 Sur-8 PTHR45752:SF209 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT PROTEIN SOC-2 HOMOLOG regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of Ras protein signal transduction#GO:0046578;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032214|UniProtKB=Q9VL00 Q9VL00 CG4968 PTHR12931:SF15 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUBAIN-LIKE ubiquitin binding#GO:0043130;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 DROME|FlyBase=FBgn0036022|UniProtKB=Q9VT23 Q9VT23 SP170 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0029765|UniProtKB=Q9W4C2 Q9W4C2 Dmel\CG16756 PTHR11407:SF75 LYSOZYME C LYSOZYME catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;lysozyme activity#GO:0003796 glycosidase#PC00110 DROME|FlyBase=FBgn0022344|UniProtKB=Q9VES8 Q9VES8 anon2A5 PTHR13126:SF0 CHAPERONE ATP11 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 chaperone#PC00072 DROME|FlyBase=FBgn0032001|UniProtKB=Q9VLR3 Q9VLR3 Dmel\CG8360 PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 nucleoside catabolic process#GO:0009164;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 deaminase#PC00088 Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144 DROME|FlyBase=FBgn0032424|UniProtKB=Q9VK96 Q9VK96 Dmel\CG17010 PTHR10584:SF166 SUGAR KINASE RIBOKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 carbohydrate kinase#PC00065;kinase#PC00137 DROME|FlyBase=FBgn0021768|UniProtKB=Q9VVA6 Q9VVA6 nudC PTHR12356:SF3 NUCLEAR MOVEMENT PROTEIN NUDC NUCLEAR MIGRATION PROTEIN NUDC macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0035780|UniProtKB=Q9VS67 Q9VS67 carboxypeptidase b1 PTHR11705:SF140 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI02848P-RELATED metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0261976|UniProtKB=Q9VQY9 Q9VQY9 Psf2 PTHR12772:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;DNA replication preinitiation complex#GO:0031261;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0263398|UniProtKB=Q9VC99 Q9VC99 Uck PTHR10285:SF70 URIDINE KINASE URIDINE-CYTIDINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;nucleoside kinase activity#GO:0019206;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149 DROME|FlyBase=FBgn0032200|UniProtKB=Q9VL16 Q9VL16 Fundc1 PTHR21346:SF0 FUN14 DOMAIN CONTAINING RE45833P autophagy#GO:0006914;cellular process#GO:0009987;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967 DROME|FlyBase=FBgn0031732|UniProtKB=Q9VMN1 Q9VMN1 Dmel\CG11149 PTHR47412:SF1 FI01434P-RELATED FI01434P-RELATED DROME|FlyBase=FBgn0014469|UniProtKB=Q27606 Q27606 Cyp4e2 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0051803|UniProtKB=Q8T3V7 Q8T3V7 Rsph9 PTHR22069:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN S18 RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 DROME|FlyBase=FBgn0031070|UniProtKB=Q9VWC7 Q9VWC7 lincRNA.1023 PTHR23161:SF2 PROTEIN CIP2A PROTEIN CIP2A phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0026361|UniProtKB=Q7KLG8 Q7KLG8 Septin5 PTHR18884:SF69 SEPTIN SEPTIN-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0037011|UniProtKB=Q9VPD2 Q9VPD2 Nubp2 PTHR23264:SF19 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DROME|FlyBase=FBgn0008646|UniProtKB=Q9VFQ3 Q9VFQ3 E5 PTHR24339:SF28 HOMEOBOX PROTEIN EMX-RELATED E5-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;cell differentiation#GO:0030154;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;head development#GO:0060322;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0261998|UniProtKB=Q9VVK6 Q9VVK6 Dmel\CG42816 PTHR19229:SF278 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0025574|UniProtKB=O77237 O77237 Pli PTHR12098:SF2 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED PROTEIN PELLINO ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0263776|UniProtKB=M9PEU1 M9PEU1 coch PTHR22950:SF460 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 4-LIKE PROTEIN amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085 membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774 secondary carrier transporter#PC00258;amino acid transporter#PC00046 DROME|FlyBase=FBgn0000640|UniProtKB=P54398 P54398 Fbp2 PTHR44229:SF8 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] ALCOHOL DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0000492|UniProtKB=Q03372 Q03372 Dr PTHR24338:SF0 HOMEOBOX PROTEIN MSX MUSCLE SEGMENTATION HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0051797|UniProtKB=Q9VIY5 Q9VIY5 CG15175 PTHR13585:SF19 CHASCON, ISOFORM D-RELATED CHASCON, ISOFORM D-RELATED DROME|FlyBase=FBgn0085297|UniProtKB=A8JNH4 A8JNH4 Dmel\CG34268 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0051410|UniProtKB=Q9VH33 Q9VH33 Npc2e PTHR11306:SF36 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NIEMANN-PICK TYPE C-2C-RELATED lipid binding#GO:0008289;steroid binding#GO:0005496;binding#GO:0005488;sterol binding#GO:0032934 sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036 DROME|FlyBase=FBgn0051717|UniProtKB=Q8T8T9 Q8T8T9 Dmel\CG31717 PTHR14969:SF13 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE AT30094P phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796 cellular anatomical structure#GO:0110165;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0003977|UniProtKB=Q9W1R5 Q9W1R5 vir PTHR23185:SF0 PROTEIN VIRILIZER HOMOLOG PROTEIN VIRILIZER HOMOLOG methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 DROME|FlyBase=FBgn0023458|UniProtKB=Q9W425 Q9W425 Rbcn-3A PTHR13950:SF9 RABCONNECTIN-RELATED RABCONNECTIN-3A cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0036222|UniProtKB=Q8SX97 Q8SX97 SdhAL PTHR11632:SF51 SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;anaerobic respiration#GO:0009061 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;respiratory chain complex#GO:0098803;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 dehydrogenase#PC00092 DROME|FlyBase=FBgn0250837|UniProtKB=Q9V3I1 Q9V3I1 dUTPase PTHR11241:SF0 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE binding#GO:0005488;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;nucleoside triphosphate diphosphatase activity#GO:0047429 carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;nucleoside monophosphate biosynthetic process#GO:0009124;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleotide catabolic process#GO:0009166;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 hydrolase#PC00121;phosphatase#PC00181 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 DROME|FlyBase=FBgn0035720|UniProtKB=Q8MZI3 Q8MZI3 DmRH5 PTHR47958:SF215 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA helicase#PC00032 DROME|FlyBase=FBgn0041582|UniProtKB=Q9W1A4 Q9W1A4 tamo PTHR15326:SF2 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC PROTEIN TAMOZHENNIC cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033257|UniProtKB=Q7JZM1 Q7JZM1 sand PTHR11003:SF356 POTASSIUM CHANNEL, SUBFAMILY K RE21922P voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0035619|UniProtKB=Q9VRM8 Q9VRM8 Alp10 PTHR11596:SF91 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0035666|UniProtKB=Q9VRS8 Q9VRS8 Jon65Aii PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0036080|UniProtKB=Q9VT92 Q9VT92 Or67d PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0051773|UniProtKB=Q9VQW0 Q9VQW0 Fpgs2 PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ligase#PC00142 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 DROME|FlyBase=FBgn0002891|UniProtKB=Q9GSR1 Q9GSR1 PolZ1 PTHR45812:SF1 DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA POLYMERASE ZETA CATALYTIC SUBUNIT catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA-directed DNA polymerase activity#GO:0003887 DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;recombinational repair#GO:0000725;DNA synthesis involved in DNA replication#GO:0090592 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0002783|UniProtKB=Q9VF03 Q9VF03 mor PTHR12802:SF184 SWI/SNF COMPLEX-RELATED BRAHMA ASSOCIATED PROTEIN 155 KDA histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 DROME|FlyBase=FBgn0038816|UniProtKB=A0A0B4KHT3 A0A0B4KHT3 Lrrk PTHR48051:SF1 FAMILY NOT NAMED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0034997|UniProtKB=D6W4U0 D6W4U0 Asm PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;organophosphate catabolic process#GO:0046434;ceramide metabolic process#GO:0006672;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764 hydrolase#PC00121;phosphodiesterase#PC00185 DROME|FlyBase=FBgn0030091|UniProtKB=Q7YZA2 Q7YZA2 CG7065 PTHR46007:SF14 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 DROME|FlyBase=FBgn0005640|UniProtKB=M9PE01 M9PE01 Eip63E PTHR24056:SF189 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;cyclin binding#GO:0030332;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein kinase complex#GO:1902911;transferase complex#GO:1990234;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035871|UniProtKB=Q9VSH3 Q9VSH3 BI-1 PTHR23291:SF133 BAX INHIBITOR-RELATED BAX INHIBITOR 1 enzyme regulator activity#GO:0030234;calcium ion transmembrane transporter activity#GO:0015085;molecular function inhibitor activity#GO:0140678;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;enzyme inhibitor activity#GO:0004857 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;response to topologically incorrect protein#GO:0035966;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057;cellular response to unfolded protein#GO:0034620;negative regulation of cell communication#GO:0010648;response to unfolded protein#GO:0006986;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;response to stress#GO:0006950;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 Apoptosis signaling pathway#P00006>Bi1#P00277 DROME|FlyBase=FBgn0051436|UniProtKB=Q8IMT3 Q8IMT3 Dmel\CG31436 PTHR11012:SF12 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0031302|UniProtKB=Q9VPW6 Q9VPW6 Dmel\CG14340 PTHR21029:SF21 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG DECIMA, ISOFORM D cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 DROME|FlyBase=FBgn0036807|UniProtKB=A0A6M3Q724 A0A6M3Q724 Dmel\CG6893 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER C4-dicarboxylate transmembrane transporter activity#GO:0015556;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;succinate transmembrane transporter activity#GO:0015141 cellular process#GO:0009987;phosphate ion transport#GO:0006817;dicarboxylic acid transport#GO:0006835;carboxylic acid transmembrane transport#GO:1905039;succinate transport#GO:0015744;transport#GO:0006810;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0034965|UniProtKB=A8DYP1 A8DYP1 ppk29 PTHR11690:SF157 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 15-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0033752|UniProtKB=Q7K264 Q7K264 Dmel\CG8569 PTHR46379:SF1 ZINC FINGER MYND DOMAIN-CONTAINING ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11 histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0032750|UniProtKB=Q9VJ06 Q9VJ06 Dus4 PTHR11082:SF31 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(20A_20B) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 RNA processing factor#PC00147 DROME|FlyBase=FBgn0030647|UniProtKB=X2JF48 X2JF48 Dmel\CG6324 PTHR24215:SF37 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE-RICH PROTEIN 1 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0016123|UniProtKB=Q24238 Q24238 Alp4 PTHR11596:SF83 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE 4 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0039274|UniProtKB=Q9VBY2 Q9VBY2 Dmel\CG11920 PTHR22734:SF2 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 snoRNA binding#GO:0030515;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0035915|UniProtKB=Q9VSM6 Q9VSM6 S-Lap1 PTHR11963:SF25 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0032240|UniProtKB=Q9VKW8 Q9VKW8 CG5356 PTHR23338:SF16 SMALL NUCLEAR RIBONUCLEOPROTEIN SM U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4 binding#GO:0005488;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;P-body assembly#GO:0033962;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;RNA splicing, via transesterification reactions#GO:0000375;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;P-body#GO:0000932;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0034580|UniProtKB=Q9W2M7 Q9W2M7 Cht8 PTHR11177:SF416 CHITINASE CHITINASE 9-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0031161|UniProtKB=Q9VRF3 Q9VRF3 Dmel\CG15445 PTHR12948:SF3 NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN NEDD8 ULTIMATE BUSTER 1 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein catabolic process#GO:0042176;regulation of catabolic process#GO:0009894 DROME|FlyBase=FBgn0289108|UniProtKB=Q9VD92 Q9VD92 Archease PTHR12682:SF11 ARCHEASE TRNA-SPLICING LIGASE-ACTIVATING FACTOR ARCHEASE catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0030521|UniProtKB=Q9VY87 Q9VY87 CtsB PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035057|UniProtKB=Q9W115 Q9W115 Dmel\CG3880 PTHR14907:SF2 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2 DROME|FlyBase=FBgn0035777|UniProtKB=Q9VS64 Q9VS64 Dmel\CG8563 PTHR11705:SF161 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI01817P-RELATED catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0051025|UniProtKB=Q8MRN4 Q8MRN4 Ppi1 PTHR39079:SF1 FI08034P-RELATED GH11706P-RELATED DROME|FlyBase=FBgn0283469|UniProtKB=Q9Y162 Q9Y162 Vps4 PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular transport#GO:0046907;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;endosomal transport#GO:0016197;organelle organization#GO:0006996;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;vacuole organization#GO:0007033;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0000426|UniProtKB=Q24297 Q24297 SmF PTHR11021:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SMALL NUCLEAR RIBONUCLEOPROTEIN F binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0039634|UniProtKB=Q9VAP8 Q9VAP8 alpha-Man-Ib PTHR11742:SF55 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039861|UniProtKB=Q9V9V7 Q9V9V7 pasha PTHR13482:SF3 MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8 MICROPROCESSOR COMPLEX SUBUNIT DGCR8 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;primary miRNA processing#GO:0031053;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774 endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 DROME|FlyBase=FBgn0038586|UniProtKB=Q9VEB2 Q9VEB2 Dmel\CG7168 PTHR15857:SF0 COMM DOMAIN CONTAINING PROTEIN 2 COMM DOMAIN-CONTAINING PROTEIN 2 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0030740|UniProtKB=Q9VXH7 Q9VXH7 Dmel\CG9917 PTHR20997:SF2 EG:BACR42I17.2 PROTEIN-RELATED EG:BACR42I17.2 PROTEIN-RELATED DROME|FlyBase=FBgn0051156|UniProtKB=Q9VCX7 Q9VCX7 CG5253 PTHR10724:SF10 30S RIBOSOMAL PROTEIN S1 S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;RNA binding#GO:0003723 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 ribosomal protein#PC00202 DROME|FlyBase=FBgn0033688|UniProtKB=A1Z8U0 A1Z8U0 Prp8 PTHR11140:SF0 PRE-MRNA SPLICING FACTOR PRP8 PRE-MRNA-PROCESSING-SPLICING FACTOR 8 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0052232|UniProtKB=Q8IRA1 Q8IRA1 t-Grip128 PTHR19302:SF27 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 4 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0035985|UniProtKB=Q9VSY0 Q9VSY0 Cpr67B PTHR12236:SF79 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 64AA-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030092|UniProtKB=Q9W385 Q9W385 fh PTHR16821:SF2 FRATAXIN FRATAXIN, MITOCHONDRIAL iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0287696|UniProtKB=Q9VV99 Q9VV99 mus302 PTHR16047:SF7 RFWD3 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RFWD3 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0261446|UniProtKB=Q9W5H1 Q9W5H1 Dmel\CG13377 PTHR48107:SF7 NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED RE15974P metabolite interconversion enzyme#PC00262;reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0051139|UniProtKB=Q9VCU4 Q9VCU4 Dmel\CG31139 PTHR12203:SF126 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 1 UDP-glucosyltransferase activity#GO:0035251;UDP-xylosyltransferase activity#GO:0035252;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;glucosyltransferase activity#GO:0046527;xylosyltransferase activity#GO:0042285 positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of Notch signaling pathway#GO:0045747;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;glycoprotein metabolic process#GO:0009100;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;positive regulation of biological process#GO:0048518;carbohydrate derivative metabolic process#GO:1901135;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0051321|UniProtKB=Q8INF8 Q8INF8 BcDNA:RH31685 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0033539|UniProtKB=Q95RG8 Q95RG8 Git PTHR46097:SF3 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488 regulation of small GTPase mediated signal transduction#GO:0051056;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;animal organ development#GO:0048513;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;regulation of G protein-coupled receptor signaling pathway#GO:0008277;transport#GO:0006810;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;head development#GO:0060322;nervous system development#GO:0007399;brain development#GO:0007420;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;system development#GO:0048731;localization#GO:0051179;cellular localization#GO:0051641;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of cell communication#GO:0010646;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 DROME|FlyBase=FBgn0039799|UniProtKB=Q9VA43 Q9VA43 Dmel\CG15543 PTHR23359:SF271 NUCLEOTIDE KINASE ADENYLATE KINASE 8 phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo purine biosynthesis#P02738>Adenylate kinase#P02896 DROME|FlyBase=FBgn0010504|UniProtKB=Q7JX82 Q7JX82 kermit PTHR12259:SF1 RGS-GAIP INTERACTING PROTEIN GIPC GH21964P scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036082|UniProtKB=Q9VT94 Q9VT94 Dmel\CG12362 PTHR11685:SF475 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0266432|UniProtKB=A0A0B4LG94 A0A0B4LG94 alphalike PTHR43294:SF13 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0034126|UniProtKB=A1ZAG1 A1ZAG1 jtb PTHR21163:SF0 PROTEIN G12 GH08205P-RELATED DROME|FlyBase=FBgn0034027|UniProtKB=Q7K1W5 Q7K1W5 Dmel\CG8187 PTHR34094:SF1 FAMILY NOT NAMED PROTEIN FAM185A DROME|FlyBase=FBgn0034230|UniProtKB=A1ZAU6 A1ZAU6 Dmel\CG4853 PTHR23113:SF356 GUANINE NUCLEOTIDE EXCHANGE FACTOR FI05912P-RELATED guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0011596|UniProtKB=O18412 O18412 fzo PTHR10465:SF3 TRANSMEMBRANE GTPASE FZO1 TRANSMEMBRANE GTPASE MARF-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle localization#GO:0051640;mitochondrion localization#GO:0051646;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;organelle fusion#GO:0048284 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 DROME|FlyBase=FBgn0036956|UniProtKB=Q9VW98 Q9VW98 wall PTHR11012:SF30 PROTEIN KINASE-LIKE DOMAIN-CONTAINING PROTEIN KINASE-LIKE DOMAIN-CONTAINING DROME|FlyBase=FBgn0032731|UniProtKB=Q9VJ26 Q9VJ26 Swip-1 PTHR13025:SF6 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 DROME|FlyBase=FBgn0058160|UniProtKB=Q95RS6 Q95RS6 Sph242 PTHR24256:SF462 TRYPTASE-RELATED LP21446P-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0038394|UniProtKB=Q9VEZ7 Q9VEZ7 Jhbp4 PTHR11008:SF33 PROTEIN TAKEOUT-LIKE PROTEIN JUVENILE HORMONE BINDING PROTEIN 4 circadian rhythm#GO:0007623;rhythmic process#GO:0048511 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0020270|UniProtKB=Q9XYZ4 Q9XYZ4 mre11 PTHR10139:SF9 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519 biological regulation#GO:0065007;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;regulation of G2/M transition of mitotic cell cycle#GO:0010389;telomere organization#GO:0032200;sexual reproduction#GO:0019953;negative regulation of mitotic cell cycle phase transition#GO:1901991;meiotic DNA double-strand break formation#GO:0042138;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle G2/M phase transition#GO:1902750;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;double-strand break repair via nonhomologous end joining#GO:0006303;telomere maintenance#GO:0000723;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic DNA damage checkpoint signaling#GO:0044773;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA recombination#GO:0006310;signaling#GO:0023052;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694 DROME|FlyBase=FBgn0039644|UniProtKB=Q961D3 Q961D3 rdog PTHR24223:SF324 ATP-BINDING CASSETTE SUB-FAMILY C LD17001P establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0013432|UniProtKB=O46098 O46098 bcn92 PTHR13166:SF7 PROTEIN C6ORF149 LYR MOTIF-CONTAINING PROTEIN 4 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 cytosol#GO:0005829;mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;sulfurtransferase complex#GO:1990228;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0033327|UniProtKB=C0HK99 C0HK99 PGRP-SC1b PTHR11022:SF75 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN SB1-RELATED signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783 immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;response to external stimulus#GO:0009605;defense response#GO:0006952 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0044324|UniProtKB=Q86BS3 Q86BS3 Chro PTHR22812:SF112 CHROMOBOX PROTEIN CHROMATOR, ISOFORM A-RELATED binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694 DROME|FlyBase=FBgn0025457|UniProtKB=Q9VAJ2 Q9VAJ2 Bub3 PTHR10971:SF36 MRNA EXPORT FACTOR AND BUB3 MITOTIC CHECKPOINT PROTEIN BUB3 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of cell cycle#GO:0045786;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251 kinetochore#GO:0000776;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0000250|UniProtKB=Q03017 Q03017 cact PTHR46680:SF3 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR CACTUS protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;molecular sequestering activity#GO:0140313;binding#GO:0005488;transcription factor binding#GO:0008134;protein sequestering activity#GO:0140311 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of canonical NF-kappaB signal transduction#GO:0043122 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 Toll pathway-drosophila#P06217>CACT#P06342 DROME|FlyBase=FBgn0026179|UniProtKB=Q9VP80 Q9VP80 Iqsec PTHR10663:SF342 GUANYL-NUCLEOTIDE EXCHANGE FACTOR FI21420P1 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0036402|UniProtKB=Q9VUB9 Q9VUB9 0670_06 PTHR21208:SF1 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 kinase#PC00137 DROME|FlyBase=FBgn0014343|UniProtKB=M9PI45 M9PI45 mirr PTHR11211:SF49 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX MIRROR, ISOFORM C RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0034715|UniProtKB=Q9W270 Q9W270 Oatp58Db PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 transporter#PC00227 DROME|FlyBase=FBgn0052237|UniProtKB=Q9VZ79 Q9VZ79 CG13703 PTHR36135:SF2 FIBROUS SHEATH CABYR-BINDING PROTEIN FIBROUS SHEATH CABYR-BINDING PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 DROME|FlyBase=FBgn0001139|UniProtKB=P16371 P16371 gro PTHR10814:SF37 TRANSDUCIN-LIKE ENHANCER PROTEIN PROTEIN GROUCHO transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 DROME|FlyBase=FBgn0036480|UniProtKB=M9MSL4 M9MSL4 Cep135 PTHR23159:SF31 CENTROSOMAL PROTEIN 2 CENTROSOMAL PROTEIN 135KDA, ISOFORM B chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0034441|UniProtKB=Q4V5E4 Q4V5E4 Dmel\CG10081 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0039683|UniProtKB=Q9VAI8 Q9VAI8 dmrt99B PTHR12322:SF53 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX-MAB RELATED 11E-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;sex differentiation#GO:0007548;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0035505|UniProtKB=B6IDT8 B6IDT8 Teh2 PTHR12335:SF5 TIPE PROTEIN TEMPERATURE-INDUCED PARALYTIC E IP20336P transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0037107|UniProtKB=Q9VP08 Q9VP08 CT22143 PTHR45080:SF45 CONTACTIN 5 IP11255P signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cell adhesion#GO:0007155;cell junction organization#GO:0034330;homophilic cell-cell adhesion#GO:0007156;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987 membrane#GO:0016020;neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424 DROME|FlyBase=FBgn0030305|UniProtKB=Q9VYY3 Q9VYY3 Uba5 PTHR10953:SF9 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0052313|UniProtKB=M9PBI0 M9PBI0 Dmel\CG32313 PTHR10334:SF565 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0052571|UniProtKB=Q8IR11 Q8IR11 TwdlX PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 DROME|FlyBase=FBgn0263863|UniProtKB=Q9VCX3 Q9VCX3 mRpL45 PTHR28554:SF1 39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML45 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0054028|UniProtKB=Q6III4 Q6III4 Dmel\CG34028 PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0027602|UniProtKB=Q86B47 Q86B47 CG8611 PTHR24031:SF89 RNA HELICASE ATP-DEPENDENT DNA HELICASE DDX31 cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0053160|UniProtKB=Q9VZS9 Q9VZS9 CG11531 PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0030828|UniProtKB=Q9VX69 Q9VX69 Dmel\CG5162 PTHR11610:SF149 LIPASE FI01450P-RELATED hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0036826|UniProtKB=Q8SWX0 Q8SWX0 arx PTHR21402:SF14 GAMETOCYTE SPECIFIC FACTOR 1-RELATED GAMETOCYTE-SPECIFIC FACTOR 1 HOMOLOG DROME|FlyBase=FBgn0028382|UniProtKB=Q9V3G3 Q9V3G3 cyp33 PTHR11071:SF593 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 chaperone#PC00072 DROME|FlyBase=FBgn0002787|UniProtKB=P26270 P26270 Rpn8 PTHR10540:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 DROME|FlyBase=FBgn0250904|UniProtKB=Q9W4B0 Q9W4B0 CG15780 PTHR48513:SF1 IP03738P IP03738P DROME|FlyBase=FBgn0003255|UniProtKB=Q7KTA0 Q7KTA0 rk PTHR24372:SF82 GLYCOPROTEIN HORMONE RECEPTOR RICKETS molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0032797|UniProtKB=B7YZX0 B7YZX0 Hasp PTHR19325:SF577 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING HIG-ANCHORING SCAFFOLD PROTEIN, ISOFORM G complement component#PC00078;defense/immunity protein#PC00090 DROME|FlyBase=FBgn0035003|UniProtKB=Q9W174 Q9W174 Dmel\CG15873 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0050428|UniProtKB=Q8MLN2 Q8MLN2 BcDNA:SD21514 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE DROME|FlyBase=FBgn0036964|UniProtKB=Q9VWA8 Q9VWA8 FRG1 PTHR12928:SF0 FRG1 PROTEIN PROTEIN FRG1 spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0031876|UniProtKB=Q9VM59 Q9VM59 Atac1 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0015831|UniProtKB=Q9VIB7 Q9VIB7 Rtnl2 PTHR45799:SF2 RETICULON-LIKE PROTEIN RETICULON-LIKE PROTEIN cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;endoplasmic reticulum tubular network organization#GO:0071786;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029 intracellular organelle#GO:0043229;axon#GO:0030424;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;neuron projection#GO:0043005;endomembrane system#GO:0012505;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0085218|UniProtKB=A8DYG6 A8DYG6 Dmel\CG34189 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0028690|UniProtKB=Q9V3Z4 Q9V3Z4 Rpn5 PTHR10855:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12 peptidase complex#GO:1905368;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 DROME|FlyBase=FBgn0053642|UniProtKB=Q4ABF9 Q4ABF9 Dmel\CG33642 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0036300|UniProtKB=Q9VTZ6 Q9VTZ6 Pmm2 PTHR10466:SF0 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262;mutase#PC00160 Mannose metabolism#P02752>P-Mannose mutase#P03019 DROME|FlyBase=FBgn0040609|UniProtKB=Q9VB45 Q9VB45 Dmel\CG3348 PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0039735|UniProtKB=Q9VAC4 Q9VAC4 Nph PTHR22747:SF18 NUCLEOPLASMIN GEO09167P1-RELATED chaperone#PC00072 DROME|FlyBase=FBgn0027783|UniProtKB=Q7KK96 Q7KK96 SMC2 PTHR43941:SF15 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2 chromatin binding#GO:0003682;binding#GO:0005488 mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;organelle fission#GO:0048285;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;nuclear division#GO:0000280;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059 chromosome#GO:0005694;chromatin#GO:0000785;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;condensin complex#GO:0000796;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0011217|UniProtKB=P25867 P25867 eff PTHR24068:SF567 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 DROME|FlyBase=FBgn0034326|UniProtKB=A1ZB58 A1ZB58 Dmel\CG18540 PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0030608|UniProtKB=Q9VXY7 Q9VXY7 Lsd-2 PTHR14024:SF53 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 2 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;lipid storage#GO:0019915;cellular process#GO:0009987;regulation of localization#GO:0032879 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0035229|UniProtKB=Q9W0E1 Q9W0E1 pns PTHR46070:SF1 PINSTRIPE, ISOFORM A PINSTRIPE, ISOFORM A molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 DROME|FlyBase=FBgn0039966|UniProtKB=Q7PLE9 Q7PLE9 Rab21 PTHR24073:SF1235 DRAB5-RELATED RAS-RELATED PROTEIN RAB-21 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 DROME|FlyBase=FBgn0030347|UniProtKB=Q9VYT0 Q9VYT0 Dmel\CG15739 PTHR19288:SF4 4-NITROPHENYLPHOSPHATASE-RELATED RE04130P-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 DROME|Gene_ORFName=Dmel_CG46507|UniProtKB=A0ACD4DAV3 A0ACD4DAV3 CG46507 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034821|UniProtKB=Q9W1U7 Q9W1U7 Dmel\CG9876 PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0034837|UniProtKB=Q9W1T1 Q9W1T1 RpL22-like PTHR10064:SF0 60S RIBOSOMAL PROTEIN L22 LARGE RIBOSOMAL SUBUNIT PROTEIN EL22 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosomal protein#PC00202 DROME|FlyBase=FBgn0034938|UniProtKB=Q9W1F5 Q9W1F5 Dmel\CG3803 PTHR23289:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HEME A SYNTHASE COX15 chaperone#PC00072 Vitamin D metabolism and pathway#P04396>FDX#P04607 DROME|FlyBase=FBgn0044452|UniProtKB=Q9VZX7 Q9VZX7 Atg2 PTHR13190:SF1 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED PROTEIN 2 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266 cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;reticulophagy#GO:0061709;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;phagophore assembly site#GO:0000407 DROME|FlyBase=FBgn0003965|UniProtKB=P20351 P20351 v PTHR10138:SF0 TRYPTOPHAN 2,3-DIOXYGENASE TRYPTOPHAN 2,3-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;heme binding#GO:0020037;catalytic activity#GO:0003824;binding#GO:0005488 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 oxygenase#PC00177 DROME|FlyBase=FBgn0053296|UniProtKB=Q7KTJ8 Q7KTJ8 Dmel\CG33296 PTHR11616:SF337 SODIUM/CHLORIDE DEPENDENT TRANSPORTER BLOATED TUBULES, ISOFORM B-RELATED transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;glycine transmembrane transporter activity#GO:0015187;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;sodium ion transport#GO:0006814;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 DROME|FlyBase=FBgn0270925|UniProtKB=B7Z0M7 B7Z0M7 Sordl PTHR43161:SF29 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;hexose biosynthetic process#GO:0019319;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0010435|UniProtKB=Q9W0X0 Q9W0X0 emp PTHR11923:SF115 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 SCAVENGER RECEPTOR CLASS B MEMBER 1 cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0034032|UniProtKB=Q7K3M9 Q7K3M9 Dmel\CG8195 PTHR23051:SF0 SOLUTE CARRIER FAMILY 35, MEMBER F5 SOLUTE CARRIER FAMILY 35 MEMBER F5 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0039387|UniProtKB=Q9VBK7 Q9VBK7 Mco3 PTHR11709:SF539 MULTI-COPPER OXIDASE FI03373P-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 oxidase#PC00175 DROME|FlyBase=FBgn0031836|UniProtKB=Q9VMB3 Q9VMB3 BcDNA:LD22339 PTHR11845:SF13 5'-DEOXYNUCLEOTIDASE HDDC2 5'-DEOXYNUCLEOTIDASE HDDC2 5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0264297|UniProtKB=Q8IRK1 Q8IRK1 CG13569-1 PTHR10334:SF613 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0036262|UniProtKB=Q9VTU9 Q9VTU9 Miox PTHR12588:SF0 MYOINOSITOL OXYGENASE INOSITOL OXYGENASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular process#GO:0009987 oxygenase#PC00177 DROME|FlyBase=FBgn0038355|UniProtKB=Q9VF44 Q9VF44 Dmel\CG4520 PTHR10802:SF3 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 IP11229P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmembrane protein transporter activity#GO:0008320 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179 mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0031414|UniProtKB=A0A1F4 A0A1F4 eys PTHR24033:SF224 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN EYES SHUT DROME|FlyBase=FBgn0033128|UniProtKB=Q7JWP5 Q7JWP5 Tsp42Eg PTHR19282:SF521 TETRASPANIN AT12771P-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0250910|UniProtKB=Q4LBB6 Q4LBB6 Octbeta3R PTHR24248:SF208 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OCTOPAMINE RECEPTOR BETA-3R signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0041188|UniProtKB=Q8SWR8 Q8SWR8 Atx2 PTHR12854:SF7 ATAXIN 2-RELATED ATAXIN-2 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032192|UniProtKB=Q9VL27 Q9VL27 Dmel\CG5731 PTHR11452:SF95 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 galactosidase#PC00104;hydrolase#PC00121 DROME|FlyBase=FBgn0004924|UniProtKB=P30189 P30189 Top1 PTHR10290:SF3 DNA TOPOISOMERASE I DNA TOPOISOMERASE 1 DNA topoisomerase#PC00017;DNA metabolism protein#PC00009 DNA replication#P00017>DNA Topisomerase#P00536;DNA replication#P00017>Top#P00530 DROME|FlyBase=FBgn0063495|UniProtKB=A1ZB70 A1ZB70 GstE5 PTHR43969:SF8 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE E13, ISOFORM A-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0029948|UniProtKB=Q9W3R2 Q9W3R2 CheA7a PTHR21112:SF13 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 7A DROME|FlyBase=FBgn0052448|UniProtKB=Q8IPS9 Q8IPS9 Dmel\CG32448 PTHR14274:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 8 SMALL INTEGRAL MEMBRANE PROTEIN 8 DROME|FlyBase=FBgn0036953|UniProtKB=Q9VW95 Q9VW95 Dmel\CG17145 PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0036772|UniProtKB=Q9VVM8 Q9VVM8 Dmel\CG5290 PTHR16193:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 27 TETRATRICOPEPTIDE REPEAT PROTEIN 27 DROME|FlyBase=FBgn0031996|UniProtKB=Q9VLS0 Q9VLS0 Dmel\CG8460 PTHR46066:SF2 CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER CHITINASE DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;oligosaccharide binding#GO:0070492;carbohydrate binding#GO:0030246 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0004087|UniProtKB=P17719 P17719 Dhfr PTHR48069:SF3 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 reductase#PC00198;oxidoreductase#PC00176 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948 DROME|FlyBase=FBgn0035943|UniProtKB=Q9VSR8 Q9VSR8 Dmel\CG5653 PTHR10742:SF398 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidase#PC00175 DROME|FlyBase=FBgn0061200|UniProtKB=Q9VXE6 Q9VXE6 Nup153 PTHR23193:SF23 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP153 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0261787|UniProtKB=Q9VIL0 Q9VIL0 brun PTHR21512:SF5 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;Golgi apparatus subcompartment#GO:0098791;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794 DROME|FlyBase=FBgn0034582|UniProtKB=Q9W2M5 Q9W2M5 Cht9 PTHR11177:SF416 CHITINASE CHITINASE 9-RELATED chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0265296|UniProtKB=Q9VS29 Q9VS29 Dscam2 PTHR10075:SF142 BASIGIN RELATED CELL ADHESION MOLECULE DSCAM2-RELATED developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;nervous system development#GO:0007399;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0038439|UniProtKB=Q9VEU1 Q9VEU1 Cad89D PTHR24026:SF129 FAT ATYPICAL CADHERIN-RELATED CADHERIN-89D cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912 cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 DROME|FlyBase=FBgn0028988|UniProtKB=Q7YTY6 Q7YTY6 Spn42Dd PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0039034|UniProtKB=Q9VCS8 Q9VCS8 Or94b PTHR21137:SF37 ODORANT RECEPTOR ODORANT RECEPTOR 46A, ISOFORM B-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0011715|UniProtKB=Q24090 Q24090 Snr1 PTHR10019:SF18 SNF5 SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 DROME|FlyBase=FBgn0003254|UniProtKB=A0A0B4KFC4 A0A0B4KFC4 rib PTHR23110:SF105 BTB DOMAIN TRANSCRIPTION FACTOR RIBBON, ISOFORM C regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0037708|UniProtKB=Q9VHB9 Q9VHB9 trmt44 PTHR21210:SF0 TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 DROME|FlyBase=FBgn0004373|UniProtKB=A0A4D6K881 A0A4D6K881 fwd PTHR10048:SF22 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE BETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742 intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;phosphatidylinositol phosphate biosynthetic process#GO:0046854;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 DROME|FlyBase=FBgn0027509|UniProtKB=Q9VQ78 Q9VQ78 Tbcd PTHR12658:SF1 BETA-TUBULIN COFACTOR D TUBULIN-SPECIFIC CHAPERONE D binding#GO:0005488;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 cell junction organization#GO:0034330;protein folding#GO:0006457;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;cytoskeleton organization#GO:0007010;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;microtubule-based process#GO:0007017;metabolic process#GO:0008152;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 chaperone#PC00072 DROME|FlyBase=FBgn0052176|UniProtKB=Q9VVG9 Q9VVG9 Dmel\CG32176 PTHR14740:SF3 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 DROME|FlyBase=FBgn0010414|UniProtKB=P51905 P51905 SerT PTHR11616:SF279 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT SEROTONIN TRANSPORTER ion binding#GO:0043167;small molecule binding#GO:0036094;solute:sodium symporter activity#GO:0015370;cation binding#GO:0043169;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;binding#GO:0005488;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;serotonin binding#GO:0051378;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;metal ion transmembrane transporter activity#GO:0046873 cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;organic hydroxy compound transport#GO:0015850;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;amino acid transport#GO:0006865;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;neurotransmitter transport#GO:0006836;monoatomic cation transmembrane transport#GO:0098655 cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 DROME|FlyBase=FBgn0039654|UniProtKB=Q9VAM5 Q9VAM5 Brd8 PTHR15398:SF4 BROMODOMAIN-CONTAINING PROTEIN 8 BROMODOMAIN-CONTAINING PROTEIN 8 DROME|FlyBase=FBgn0032265|UniProtKB=Q9VKT8 Q9VKT8 Dmel\CG18301 PTHR11005:SF144 LYSOSOMAL ACID LIPASE-RELATED AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0260933|UniProtKB=Q7KTZ4 Q7KTZ4 rempA PTHR15722:SF7 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;cellular component organization#GO:0016043;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intraciliary transport particle A#GO:0030991;membraneless organelle#GO:0043228;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930 structural protein#PC00211 DROME|FlyBase=FBgn0003884|UniProtKB=P06603 P06603 alphaTub84B PTHR11588:SF501 TUBULIN TUBULIN ALPHA CHAIN purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278 supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;tubulin#PC00228 DROME|FlyBase=FBgn0035522|UniProtKB=Q9VZE8 Q9VZE8 1273 PTHR23197:SF11 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING RE03558P molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0027950|UniProtKB=A0A0B4KGZ0 A0A0B4KGZ0 MBD-like PTHR12396:SF63 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG BINDING DOMAIN PROTEIN-LIKE, ISOFORM C regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;constitutive heterochromatin formation#GO:0140719;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0051087|UniProtKB=Q9VBS6 Q9VBS6 Dmel\CG31087 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0004436|UniProtKB=P25153 P25153 Ubc6 PTHR24067:SF392 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2-17 KDA acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;catabolic process#GO:0009056;response to stimulus#GO:0050896;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687 ubiquitin ligase complex#GO:0000151;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 DROME|FlyBase=FBgn0036490|UniProtKB=Q9VUM4 Q9VUM4 Prx1 PTHR10681:SF163 THIOREDOXIN PEROXIDASE PEROXIREDOXIN 2-RELATED peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 response to oxidative stress#GO:0006979;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to stimulus#GO:0050896;catabolic process#GO:0009056;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;response to stress#GO:0006950;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 peroxidase#PC00180;oxidoreductase#PC00176 DROME|FlyBase=FBgn0035426|UniProtKB=Q9VZS0 Q9VZS0 Dmel\CG12078 PTHR12210:SF70 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 protein phosphatase#PC00195 DROME|FlyBase=FBgn0010877|UniProtKB=Q9VE96 Q9VE96 l(3)05822 PTHR14167:SF48 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 19 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0034012|UniProtKB=A1ZA01 A1ZA01 Hr51 PTHR24083:SF4 NUCLEAR HORMONE RECEPTOR PHOTORECEPTOR-SPECIFIC NUCLEAR RECEPTOR transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0037816|UniProtKB=Q9VGZ1 Q9VGZ1 CG6345 PTHR43020:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1 MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;mitochondrial RNA modification#GO:1900864;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0039257|UniProtKB=D0UGE6 D0UGE6 tnc PTHR46698:SF9 CROSSVEINLESS 2 TENECTIN ISOFORM 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0037589|UniProtKB=A0A1Z1CGZ7 A0A1Z1CGZ7 Obp85a PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0038506|UniProtKB=Q9VEK4 Q9VEK4 Dmel\CG5860 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 aspartic protease#PC00053;protease#PC00190 DROME|FlyBase=FBgn0032105|UniProtKB=Q9VLD6 Q9VLD6 borr PTHR16040:SF7 AUSTRALIN, ISOFORM A-RELATED AUSTRALIN, ISOFORM A-RELATED metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;chromosome localization#GO:0050000;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle fission#GO:0048285;localization#GO:0051179;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278 membraneless organelle#GO:0043228;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630 DROME|FlyBase=FBgn0039469|UniProtKB=Q9VB95 Q9VB95 TwdlC PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 DROME|FlyBase=FBgn0260446|UniProtKB=Q9V3Q9 Q9V3Q9 GABA-B-R1 PTHR10519:SF77 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 DROME|FlyBase=FBgn0031144|UniProtKB=B7Z152 B7Z152 Dmel\CG1529 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0000535|UniProtKB=Q02280 Q02280 eag PTHR10217:SF642 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;metal ion transport#GO:0030001;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transport#GO:0006810 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0033818|UniProtKB=A1Z9B0 A1Z9B0 Dmel\CG4712 PTHR15654:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 184 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0004514|UniProtKB=P22270 P22270 Oct-TyrR PTHR24248:SF214 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TYRAMINE_OCTOPAMINE RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034350|UniProtKB=Q9V8I2 Q9V8I2 Lamtor2 PTHR13323:SF4 LATE ENDOSOMAL/LYSOSOMAL MP1 INTERACTING PROTEIN RAGULATOR COMPLEX PROTEIN LAMTOR2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of TORC1 signaling#GO:1904263;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 DROME|FlyBase=FBgn0035484|UniProtKB=Q9VZJ8 Q9VZJ8 Dmel\CG11594 PTHR43435:SF4 RIBULOKINASE FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 Ascorbate degradation#P02729>L-xylulose kinase#P02849;Pentose phosphate pathway#P02762>D-Ribulo Kinase#P03077 DROME|FlyBase=FBgn0035060|UniProtKB=Q9W111 Q9W111 Eps-15 PTHR11216:SF176 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE CLONE 15, ISOFORM A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197 membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;clathrin coat#GO:0030118;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0043825|UniProtKB=Q9VKS9 Q9VKS9 Acp PTHR11005:SF144 LYSOSOMAL ACID LIPASE-RELATED AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0083978|UniProtKB=Q8IQI9 Q8IQI9 CG11271 PTHR41153:SF2 RE41427P RE41427P DROME|FlyBase=FBgn0026326|UniProtKB=Q7KND8 Q7KND8 Mad1 PTHR23168:SF0 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;regulation of mitotic sister chromatid segregation#GO:0033047;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular component organization or biogenesis#GO:0071840;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;signal transduction#GO:0007165;cellular process#GO:0009987;nuclear division#GO:0000280;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;cell communication#GO:0007154;localization#GO:0051179;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;organelle localization#GO:0051640;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;mitotic metaphase chromosome alignment#GO:0007080;negative regulation of cell cycle#GO:0045786;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;chromosome localization#GO:0050000;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic spindle assembly checkpoint signaling#GO:0007094;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;cellular component organization#GO:0016043 spindle#GO:0005819;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;organelle envelope#GO:0031967;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0001325|UniProtKB=P07247 P07247 Kr PTHR24390:SF228 ZINC FINGER PROTEIN PROTEIN KRUEPPEL sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0285937|UniProtKB=O18332 O18332 Rab1 PTHR24073:SF1237 DRAB5-RELATED FI01544P hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component assembly#GO:0022607;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;autophagosome organization#GO:1905037;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;intracellular protein transport#GO:0006886;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;vacuole organization#GO:0007033;organelle assembly#GO:0070925 somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell body#GO:0044297;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 small GTPase#PC00208;G-protein#PC00020 DROME|FlyBase=FBgn0036599|UniProtKB=Q9VV23 Q9VV23 Dmel\CG13044 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0021856|UniProtKB=Q9VID7 Q9VID7 l(2)k14505 PTHR21013:SF10 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2 chaperone#PC00072 DROME|FlyBase=FBgn0031735|UniProtKB=Q9VMM8 Q9VMM8 Dmel\CG11029 PTHR21325:SF31 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED phospholipase#PC00186 DROME|FlyBase=FBgn0262100|UniProtKB=C0PDE0 C0PDE0 CG7341-RB PTHR10994:SF193 RETICULON RETICULON-LIKE PROTEIN membrane traffic protein#PC00150 DROME|FlyBase=FBgn0034739|UniProtKB=Q9W240 Q9W240 cg3927 PTHR11208:SF140 RNA-BINDING PROTEIN RELATED GH05812P-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0026428|UniProtKB=M9PJN5 M9PJN5 HDAC6 PTHR10625:SF38 HISTONE DEACETYLASE HDAC1-RELATED PROTEIN DEACETYLASE HDAC6 histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cytoplasm#GO:0005737;cytosol#GO:0005829 DROME|FlyBase=FBgn0031065|UniProtKB=A0A4D6K5P9 A0A4D6K5P9 Dmel\CG14234 PTHR31247:SF5 TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER TRANSMEMBRANE PROTEIN 198 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0264743|UniProtKB=Q7KTP7 Q7KTP7 CG5822 PTHR24180:SF45 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN 39 kinase modulator#PC00140;kinase inhibitor#PC00139 DROME|FlyBase=FBgn0036809|UniProtKB=Q9VVS2 Q9VVS2 Dmel\CG12477 PTHR11224:SF10 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032719|UniProtKB=Q9VJ40 Q9VJ40 Dmel\CG17321 PTHR22776:SF102 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RH30783P regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038519|UniProtKB=Q9VEJ0 Q9VEJ0 Prx3 PTHR10681:SF182 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cellular process#GO:0009987;response to stress#GO:0006950;hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;response to stimulus#GO:0050896;catabolic process#GO:0009056;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;response to oxidative stress#GO:0006979 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;peroxidase#PC00180 DROME|FlyBase=FBgn0039344|UniProtKB=Q9VBQ2 Q9VBQ2 Dmel\CG4582 PTHR11610:SF169 LIPASE GH15759P-RELATED hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0010329|UniProtKB=Q86B61 Q86B61 Tbh PTHR10157:SF44 DOPAMINE BETA HYDROXYLASE RELATED TYRAMINE BETA-HYDROXYLASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to alcohol#GO:0097305;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020 hydroxylase#PC00122 Dopamine receptor mediated signaling pathway#P05912>DBH#P05955;Adrenaline and noradrenaline biosynthesis#P00001>DBH#P00063 DROME|FlyBase=FBgn0040797|UniProtKB=Q9VV12 Q9VV12 Dmel\CG13066 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0033543|UniProtKB=Q7JZB1 Q7JZB1 Daao1 PTHR11530:SF17 D-AMINO ACID OXIDASE RE49860P catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 oxidase#PC00175 DROME|FlyBase=FBgn0001079|UniProtKB=P23647 P23647 fu PTHR22983:SF7 PROTEIN KINASE RELATED SERINE_THREONINE-PROTEIN KINASE 36 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Hedgehog signaling pathway#P00025>Fused#P00686 DROME|FlyBase=FBgn0034882|UniProtKB=Q9W1M4 Q9W1M4 Eglp1 PTHR19139:SF270 AQUAPORIN TRANSPORTER ENTOMOGLYCEROPORIN 1-RELATED channel activity#GO:0015267;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 fluid transport#GO:0042044;establishment of localization#GO:0051234;water transport#GO:0006833;localization#GO:0051179;transport#GO:0006810 apical part of cell#GO:0045177;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;apical plasma membrane#GO:0016324;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0030596|UniProtKB=Q9VY02 Q9VY02 Dm GMCgamma1 PTHR11552:SF229 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE ECDYSONE OXIDASE-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0085190|UniProtKB=A1A6Q5 A1A6Q5 Dmel\CG34161 PTHR10029:SF3 ACYLPHOSPHATASE ACYLPHOSPHATASE-1 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0038300|UniProtKB=Q9VFC0 Q9VFC0 Mau2 PTHR21394:SF0 MAU2 CHROMATID COHESION FACTOR HOMOLOG MAU2 CHROMATID COHESION FACTOR HOMOLOG catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276;mitotic sister chromatid cohesion#GO:0007064;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0000299|UniProtKB=P08120 P08120 Col4a1 PTHR24023:SF1137 COLLAGEN ALPHA COLLAGEN ALPHA-1(IV) CHAIN-RELATED extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 DROME|FlyBase=FBgn0038541|UniProtKB=Q9VEG2 Q9VEG2 TyrRII PTHR24248:SF207 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR IP13425P-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037428|UniProtKB=Q9VNP0 Q9VNP0 Osi18 PTHR21879:SF13 FI03362P-RELATED-RELATED OSIRIS 18 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0085213|UniProtKB=A8DYD4 A8DYD4 Dmel\CG34184 PTHR21398:SF22 AGAP007094-PA IP12060P-RELATED DROME|FlyBase=FBgn0031033|UniProtKB=Q9VWG5 Q9VWG5 Dmel\CG14219 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0052793|UniProtKB=Q9W4V0 Q9W4V0 CG3591 PTHR14754:SF34 TRANSCRIPTION ELONGATION FACTOR A TRICHOHYALIN general transcription factor#PC00259 DROME|FlyBase=FBgn0003423|UniProtKB=Q04499 Q04499 slgA PTHR13914:SF0 PROLINE OXIDASE PROLINE DEHYDROGENASE-RELATED heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidase#PC00175 Huntington disease#P00029>Proline oxidase#G01529 DROME|FlyBase=FBgn0005777|UniProtKB=Q9VH81 Q9VH81 PpD3 PTHR45668:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 5 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein phosphatase#PC00195 DROME|FlyBase=FBgn0010772|UniProtKB=Q7KTT0 Q7KTT0 Xe7 PTHR12484:SF4 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A DROME|FlyBase=FBgn0010768|UniProtKB=Q9VDZ3 Q9VDZ3 sqz PTHR23235:SF191 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 384 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0010316|UniProtKB=Q7JNL9 Q7JNL9 dap PTHR10265:SF45 CYCLIN-DEPENDENT KINASE INHIBITOR 1 DACAPO enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle#GO:0007346;negative regulation of mitotic cell cycle phase transition#GO:1901991;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 kinase modulator#PC00140;kinase inhibitor#PC00139 DROME|FlyBase=FBgn0285917|UniProtKB=A0A0B4KEU2 A0A0B4KEU2 sbb PTHR21564:SF5 BRAKELESS PROTEIN SCRIBBLER, ISOFORM J regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0034923|UniProtKB=Q9W1H3 Q9W1H3 Upf3 PTHR13112:SF0 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN FI21285P1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;positive regulation of protein metabolic process#GO:0051247;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0053341|UniProtKB=Q7KS23 Q7KS23 Dmel\CG33341 PTHR21253:SF0 F-BOX ONLY PROTEIN 11-RELATED F-BOX ONLY PROTEIN 11-RELATED DROME|FlyBase=FBgn0037328|UniProtKB=Q9VNB9 Q9VNB9 RpL35A PTHR10902:SF0 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0051233|UniProtKB=Q8MRN5 Q8MRN5 CG5839 PTHR11533:SF290 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0028400|UniProtKB=Q9U6P7 Q9U6P7 Syt4 PTHR10024:SF369 SYNAPTOTAGMIN FI18813P1 molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;organelle organization#GO:0006996;vesicle organization#GO:0016050;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;regulated exocytosis#GO:0045055;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;positive regulation of cellular component organization#GO:0051130;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;membrane organization#GO:0061024;positive regulation of cellular process#GO:0048522;membrane fusion#GO:0061025;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle fusion#GO:0006906;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of exocytosis#GO:0017157;secretion#GO:0046903;localization#GO:0051179;regulation of secretion#GO:0051046;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signal release#GO:0023061 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;axon#GO:0030424;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory vesicle#GO:0099503;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 DROME|FlyBase=FBgn0011481|UniProtKB=A0A0B4KGW6 A0A0B4KGW6 Ssdp PTHR12610:SF12 SINGLE STRANDED DNA BINDING PROTEIN SEQUENCE-SPECIFIC SINGLE-STRANDED DNA-BINDING PROTEIN, ISOFORM D DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0085296|UniProtKB=A1A6X5 A1A6X5 Dmel\CG34267 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0029804|UniProtKB=Q9W478 Q9W478 Dmel\CG3097 PTHR11705:SF161 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI01817P-RELATED catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0031635|UniProtKB=Q9VR33 Q9VR33 tank PTHR21389:SF0 P53 INDUCED PROTEIN ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0025573|UniProtKB=Q7KVM5 Q7KVM5 PpN58A PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 DROME|FlyBase=FBgn0037372|UniProtKB=Q9VNH5 Q9VNH5 Dcps PTHR12978:SF0 HISTIDINE TRIAD HIT PROTEIN MEMBER M7GPPPX DIPHOSPHATASE nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 hydrolase#PC00121 DROME|FlyBase=FBgn0052673|UniProtKB=Q8IRK8 Q8IRK8 Rab9E PTHR47980:SF101 LD44762P IP08727P-RELATED vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;exocytosis#GO:0006887;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810;endocytic recycling#GO:0032456;export from cell#GO:0140352;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;localization within membrane#GO:0051668 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;trans-Golgi network transport vesicle#GO:0030140;intracellular organelle#GO:0043229;endosome#GO:0005768;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136 DROME|FlyBase=FBgn0085428|UniProtKB=A8DWJ8 A8DWJ8 Nox PTHR11972:SF58 NADPH OXIDASE NADPH OXIDASE 5 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664 response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;defense response#GO:0006952 catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;oxidase#PC00175 DROME|FlyBase=FBgn0039338|UniProtKB=Q9GQN5 Q9GQN5 XNP PTHR45797:SF3 RAD54-LIKE ATP-DEPENDENT HELICASE ATRX ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0013755|UniProtKB=Q24039 Q24039 Bro PTHR10276:SF3 CORE-BINDING FACTOR, BETA SUBUNIT CORE-BINDING FACTOR SUBUNIT BETA binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0035663|UniProtKB=Q9VRS5 Q9VRS5 SP127 PTHR24253:SF201 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0000392|UniProtKB=Q9VMA3 Q9VMA3 cup PTHR12269:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER transporter#PC00227 DROME|FlyBase=FBgn0051551|UniProtKB=Q8IPP9 Q8IPP9 CG11005 PTHR14754:SF34 TRANSCRIPTION ELONGATION FACTOR A TRICHOHYALIN general transcription factor#PC00259 DROME|FlyBase=FBgn0050053|UniProtKB=Q058Y4 Q058Y4 Dmel\CG30053 PTHR12480:SF40 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD IP10855P oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;sequence-specific DNA binding#GO:0043565;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;binding#GO:0005488;nucleic acid binding#GO:0003676;dioxygenase activity#GO:0051213;DNA binding#GO:0003677 regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular component organization#GO:0051130;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein-containing complex disassembly#GO:0043244;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0051248|UniProtKB=Q9VI66 Q9VI66 CG2640 PTHR20905:SF28 N-ACETYLTRANSFERASE-RELATED GH28833P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 transferase#PC00220;acetyltransferase#PC00038 DROME|FlyBase=FBgn0000278|UniProtKB=P14956 P14956 CecB PTHR38329:SF1 CECROPIN-A1-RELATED CECROPIN-A1-RELATED defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;defense response#GO:0006952;response to external stimulus#GO:0009605;antibacterial humoral response#GO:0019731;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030914|UniProtKB=Q9VWW1 Q9VWW1 Dmel\CG6106 PTHR43668:SF2 ALLANTOINASE ALLANTOINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152 hydrolase#PC00121 Allantoin degradation#P02725>Allantoinase#P02822;De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydroorotase#P02928 DROME|FlyBase=FBgn0031097|UniProtKB=Q9VR79 Q9VR79 obst-A PTHR23301:SF110 CHITIN BINDING PERITROPHIN-A LD43683P binding#GO:0005488;carbohydrate derivative binding#GO:0097367;structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037934|UniProtKB=Q9VGJ8 Q9VGJ8 Dmel\CG6830 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0039234|UniProtKB=Q9VC27 Q9VC27 Nct PTHR21092:SF1 NICASTRIN NICASTRIN proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 Alzheimer disease-presenilin pathway#P00004>Nicastrin#P00115;Notch signaling pathway#P00045>Nicastrin#P01108;Alzheimer disease-amyloid secretase pathway#P00003>Nicastrin#P00095 DROME|FlyBase=FBgn0031573|UniProtKB=Q9VQV3 Q9VQV3 cg3407 PTHR24390:SF272 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 76 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0033884|UniProtKB=A1Z9I6 A1Z9I6 anon-EST:GressD1 PTHR13198:SF4 RING FINGER PROTEIN 25 E3 UBIQUITIN-PROTEIN LIGASE RNF25 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0263601|UniProtKB=Q9VUX2 Q9VUX2 mib1 PTHR24202:SF53 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modification by small protein conjugation or removal#GO:0070647;cell communication#GO:0007154;localization#GO:0051179;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;signaling#GO:0023052;metabolic process#GO:0008152;transport#GO:0006810;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;establishment of localization#GO:0051234;import into cell#GO:0098657;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0036781|UniProtKB=Q9VVP0 Q9VVP0 Dmel\CG13699 PTHR17571:SF34 URINARY PROTEIN RUP /ACROSOMAL PROTEIN SP-10 ACROSOMAL PROTEIN SP-10 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982 DROME|FlyBase=FBgn0260646|UniProtKB=E1JI09 E1JI09 Dmel\CG42538 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0038474|UniProtKB=Q9VEN6 Q9VEN6 mRpS11 PTHR11759:SF76 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0039696|UniProtKB=Q9VAH2 Q9VAH2 Rnb PTHR23312:SF8 ARMC5 ARMADILLO REPEAT-CONTAINING -RELATED ARMADILLO REPEAT-CONTAINING PROTEIN 5 anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502 DROME|FlyBase=FBgn0000536|UniProtKB=P54352 P54352 eas PTHR22603:SF66 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 DROME|FlyBase=FBgn0261872|UniProtKB=Q59E33 Q59E33 scaf6 PTHR12323:SF0 SR-RELATED CTD ASSOCIATED FACTOR 6 CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN calcium ion homeostasis#GO:0055074;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039867|UniProtKB=Q9V9V0 Q9V9V0 CstF50 PTHR44133:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0015036|UniProtKB=O46054 O46054 Cyp4ae1 PTHR24291:SF187 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4AE1-RELATED oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0039736|UniProtKB=Q9VAC2 Q9VAC2 Dmel\CG7912 PTHR11814:SF132 SULFATE TRANSPORTER LD38576P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0039141|UniProtKB=Q8I0P1 Q8I0P1 spas PTHR23074:SF173 AAA DOMAIN-CONTAINING SPASTIN hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on a protein#GO:0140096;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;cell morphogenesis#GO:0000902;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0015391|UniProtKB=Q9V3A7 Q9V3A7 glu PTHR18937:SF172 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;organelle fission#GO:0048285;nuclear division#GO:0000280 intracellular organelle#GO:0043229;condensin complex#GO:0000796;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0032519|UniProtKB=Q9VJY5 Q9VJY5 Dmel\CG16957 PTHR10281:SF106 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED IP06960P-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0261534|UniProtKB=Q9V3Y3 Q9V3Y3 l(2)34Fc PTHR45828:SF56 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE DEFENSE PROTEIN L(2)34FC cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0037231|UniProtKB=Q9VN02 Q9VN02 Vps24 PTHR10476:SF1 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 3 vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0261461|UniProtKB=Q9VWL7 Q9VWL7 RhoGAP18B PTHR23176:SF0 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE ACTIVATING PROTEIN AT 18B, ISOFORM C enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0034408|UniProtKB=A0A0B4LFU3 A0A0B4LFU3 sano PTHR14454:SF11 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER SERRANO, ISOFORM F DROME|FlyBase=FBgn0085454|UniProtKB=A8JQT2 A8JQT2 CG12584 PTHR31183:SF1 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 53 structural protein#PC00211 DROME|FlyBase=FBgn0045862|UniProtKB=A0A0B4KH64 A0A0B4KH64 btz PTHR13434:SF0 PROTEIN CASC3 PROTEIN CASC3 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DROME|FlyBase=FBgn0034488|UniProtKB=Q7K3B7 Q7K3B7 Hacl PTHR43710:SF2 2-HYDROXYACYL-COA LYASE 2-HYDROXYACYL-COA LYASE 1 anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;cation binding#GO:0043169 oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;lyase#PC00144 DROME|FlyBase=FBgn0042177|UniProtKB=M9PFR8 M9PFR8 Arts PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 transporter#PC00227 DROME|FlyBase=FBgn0260011|UniProtKB=Q9V392 Q9V392 NimC4 PTHR24047:SF32 FI01909P-RELATED FI01909P-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0039209|UniProtKB=Q9VC61 Q9VC61 REPTOR PTHR21552:SF2 ADULT RETINA PROTEIN CREB3 REGULATORY FACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036752|UniProtKB=Q9VVK5 Q9VVK5 Adgf-A PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000 nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;nucleoside catabolic process#GO:0009164;purine-containing compound biosynthetic process#GO:0072522;purine nucleoside metabolic process#GO:0042278;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;adenosine metabolic process#GO:0046085;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144 cytosol#GO:0005829;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 deaminase#PC00088 DROME|FlyBase=FBgn0051973|UniProtKB=Q9VPI3 Q9VPI3 Cda5 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B DROME|FlyBase=FBgn0011592|UniProtKB=A1Z920 A1Z920 fra PTHR10075:SF136 BASIGIN RELATED FI24025P1 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0004784|UniProtKB=P13677 P13677 inaC PTHR24356:SF390 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C, BRAIN ISOZYME-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKC#P00568;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;PDGF signaling pathway#P00047>PKC#P01150;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Apoptosis signaling pathway#P00006>PKCs#P00318;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565 DROME|FlyBase=FBgn0020764|UniProtKB=O18680 O18680 Alas PTHR13693:SF108 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 heme biosynthetic process#GO:0006783;primary metabolic process#GO:0044238;pigment metabolic process#GO:0042440;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 transaminase#PC00216 DROME|FlyBase=FBgn0010591|UniProtKB=Q9V7Y2 Q9V7Y2 Sply PTHR42735:SF6 FAMILY NOT NAMED SPHINGOSINE-1-PHOSPHATE LYASE 1 catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832 catabolic process#GO:0009056;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0085206|UniProtKB=A8DYV0 A8DYV0 Dmel\CG34177 PTHR39957:SF1 AT09846P1-RELATED AT09846P1-RELATED DROME|FlyBase=FBgn0032749|UniProtKB=Q9VJ07 Q9VJ07 Phlpp PTHR45752:SF208 LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE PHLPP-LIKE PROTEIN hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0052225|UniProtKB=Q8IQV4 Q8IQV4 Dmel\CG32225 PTHR11506:SF45 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5 establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of protein localization#GO:0045184 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0039386|UniProtKB=Q9VBK8 Q9VBK8 Sodq PTHR10003:SF91 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;copper ion binding#GO:0005507 response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 oxidoreductase#PC00176 DROME|FlyBase=FBgn0039488|UniProtKB=Q9VB74 Q9VB74 Nkap PTHR13087:SF0 NF-KAPPA B ACTIVATING PROTEIN NFKB ACTIVATING PROTEIN LIKE biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0030990|UniProtKB=Q9VWL4 Q9VWL4 Dmel\CG7556 PTHR44653:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 DROME|FlyBase=FBgn0051072|UniProtKB=A0A0B4KH68 A0A0B4KH68 Lerp PTHR15071:SF17 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR binding#GO:0005488;growth factor binding#GO:0019838;protein binding#GO:0005515 protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;protein localization to lysosome#GO:0061462;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;protein localization to vacuole#GO:0072665;lysosomal transport#GO:0007041;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Apoptosis signaling pathway#P00006>IGFR2#P00282;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895 DROME|FlyBase=FBgn0029959|UniProtKB=Q9W3Q0 Q9W3Q0 Rab39 PTHR47979:SF53 DRAB11-RELATED FI07418P nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0029733|UniProtKB=Q9W4G1 Q9W4G1 CT21430 PTHR18945:SF843 NEUROTRANSMITTER GATED ION CHANNEL PH-SENSITIVE CHLORIDE CHANNEL 2 ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0003295|UniProtKB=Q9W0F8 Q9W0F8 ru PTHR45840:SF2 RHOMBOID-RELATED PROTEIN PROTEIN RHOMBOID-RELATED DROME|FlyBase=FBgn0037675|UniProtKB=Q9VHG0 Q9VHG0 HP1e PTHR22812:SF163 CHROMOBOX PROTEIN HETEROCHROMATIN PROTEIN 1E binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0030688|UniProtKB=Q9VXP8 Q9VXP8 Dmel\CG8952 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0033428|UniProtKB=Q9V595 Q9V595 Urod PTHR21091:SF169 METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED UROPORPHYRINOGEN DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;lyase activity#GO:0016829 heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;porphyrin-containing compound biosynthetic process#GO:0006779;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155 Heme biosynthesis#P02746>Uroporphyrinogen decarboxylase#P02975 DROME|FlyBase=FBgn0053499|UniProtKB=B5RJJ8 B5RJJ8 Sdic4 PTHR12442:SF22 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;intracellular transport#GO:0046907;transport#GO:0006810;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;localization#GO:0051179;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0037481|UniProtKB=Q9I7L4 Q9I7L4 MAGE PTHR11736:SF14 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0259188|UniProtKB=B7Z0X6 B7Z0X6 Ir7f PTHR42643:SF52 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 11A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0032242|UniProtKB=Q9VKW5 Q9VKW5 Dmel\CG5355 PTHR42881:SF2 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 Vasopressin synthesis#P04395>Endo Peptidase#P04596 DROME|FlyBase=FBgn0004362|UniProtKB=Q05783 Q05783 HmgD PTHR48112:SF20 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN D-RELATED cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 DROME|FlyBase=FBgn0047038|UniProtKB=Q9VTB4 Q9VTB4 ND-13B PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;electron transport chain#GO:0022900;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091 respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176 DROME|FlyBase=FBgn0036934|UniProtKB=Q9VW75 Q9VW75 sNPF-R PTHR24235:SF29 NEUROPEPTIDE Y RECEPTOR GH23382P G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0037601|UniProtKB=Q9VHP4 Q9VHP4 Cyp313b1 PTHR24305:SF224 CYTOCHROME P450 CYTOCHROME P450 313A1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0042103|UniProtKB=Q9I7K8 Q9I7K8 Dmel\CG18746 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0035171|UniProtKB=Q9W0L8 Q9W0L8 Dmel\CG12502 PTHR31815:SF1 AGAP005329-PA TRANSMEMBRANE PROTEIN 200C DROME|FlyBase=FBgn0000100|UniProtKB=P19889 P19889 RpLP0 PTHR45699:SF3 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10 rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0033572|UniProtKB=Q4V5R4 Q4V5R4 polyph PTHR22950:SF340 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN-RELATED L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0038365|UniProtKB=Q9VF34 Q9VF34 FBpp0082632 PTHR19143:SF476 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0287184|UniProtKB=Q7PLB8 Q7PLB8 FASN3 PTHR43775:SF23 FATTY ACID SYNTHASE FATTY ACID SYNTHASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 DROME|FlyBase=FBgn0030525|UniProtKB=Q9VY83 Q9VY83 Galml2 PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857 glucose metabolic process#GO:0006006;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 epimerase/racemase#PC00096 DROME|FlyBase=FBgn0085471|UniProtKB=Q29QT4 Q29QT4 Dmel\CG34442 PTHR21398:SF22 AGAP007094-PA IP12060P-RELATED DROME|FlyBase=FBgn0259162|UniProtKB=Q9VRA9 Q9VRA9 RunxB PTHR11950:SF48 RUNT RELATED RUNT RELATED B double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 DROME|FlyBase=FBgn0011273|UniProtKB=P49258 P49258 Acam PTHR23050:SF552 CALCIUM BINDING PROTEIN AT16150P-RELATED ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;cation binding#GO:0043169;molecular function regulator activity#GO:0098772 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 DROME|FlyBase=FBgn0259237|UniProtKB=Q9VD85 Q9VD85 CG31177 PTHR11533:SF308 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0038968|UniProtKB=Q9VD07 Q9VD07 Dmel\CG12499 PTHR13500:SF0 NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0061492|UniProtKB=Q9VRU2 Q9VRU2 loj PTHR22811:SF45 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 6 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708 vesicle coat protein#PC00235;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0086687|UniProtKB=Q7K4Y0 Q7K4Y0 Desat1 PTHR11351:SF104 ACYL-COA DESATURASE DESATURASE 1, ISOFORM A-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;unsaturated fatty acid biosynthetic process#GO:0006636;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 DROME|FlyBase=FBgn0034480|UniProtKB=A1ZBR1 A1ZBR1 Dmel\CG16898 PTHR11012:SF13 PROTEIN KINASE-LIKE DOMAIN-CONTAINING AT27361P-RELATED DROME|FlyBase=FBgn0031929|UniProtKB=Q9VLZ2 Q9VLZ2 Dmel\CG18585 PTHR11705:SF123 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0086558|UniProtKB=Q9W418 Q9W418 Ubi-p5E PTHR10666:SF438 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN ES31 FUSION PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0035415|UniProtKB=Q9VZT2 Q9VZT2 Dmel\CG14966 PTHR13420:SF7 UPF0235 PROTEIN C15ORF40 UPF0235 PROTEIN C15ORF40 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039471|UniProtKB=Q9VB93 Q9VB93 Dmel\CG6295 PTHR11610:SF178 LIPASE FI01825P-RELATED lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032304|UniProtKB=Q9VKP6 Q9VKP6 Dmel\CG17134 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;aspartic protease#PC00053 DROME|FlyBase=FBgn0028936|UniProtKB=Q9VJU6 Q9VJU6 NimB5 PTHR24047:SF32 FI01909P-RELATED FI01909P-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0264542|UniProtKB=M9PEE4 M9PEE4 hwt PTHR15127:SF32 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN D protein binding#GO:0005515;binding#GO:0005488 DROME|FlyBase=FBgn0266019|UniProtKB=Q8SY41 Q8SY41 rudhira PTHR13268:SF0 BREAST CARCINOMA AMPLIFIED SEQUENCE 3 BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 catabolic process#GO:0009056;response to stimulus#GO:0050896;macroautophagy#GO:0016236;cellular component organization#GO:0016043;response to stress#GO:0006950;response to nutrient levels#GO:0031667;response to starvation#GO:0042594;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;metabolic process#GO:0008152 phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0003117|UniProtKB=P52168 P52168 pnr PTHR10071:SF337 TRANSCRIPTION FACTOR GATA FAMILY MEMBER BOX A-BINDING FACTOR-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0032415|UniProtKB=Q86BL6 Q86BL6 rho-6 PTHR45840:SF10 RHOMBOID-RELATED PROTEIN RHOMBOID-6, ISOFORM B serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 DROME|FlyBase=FBgn0012036|UniProtKB=Q9VLC5 Q9VLC5 Aldh PTHR11699:SF310 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE (NAD(+)) oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;metabolic process#GO:0008152;aldehyde catabolic process#GO:0046185;catabolic process#GO:0009056 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 DROME|FlyBase=FBgn0026713|UniProtKB=Q9VY54 Q9VY54 Prp16 PTHR18934:SF91 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16 RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0033902|UniProtKB=Q7JVI3 Q7JVI3 eIF3m PTHR15350:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152 eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028920|UniProtKB=Q9V3A0 Q9V3A0 CT25774 PTHR20993:SF0 GH07914P GH07914P DROME|FlyBase=FBgn0031957|UniProtKB=Q8SZP2 Q8SZP2 TwdlE PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 DROME|FlyBase=FBgn0033775|UniProtKB=Q9V6H1 Q9V6H1 Cyp9h1 PTHR24292:SF54 CYTOCHROME P450 CYTOCHROME P450 9B1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034109|UniProtKB=Q7K231 Q7K231 CYC4 PTHR45625:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2 aminoacyltransferase activity#GO:0016755;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;cis-trans isomerase activity#GO:0016859;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0033351|UniProtKB=A1Z7K8 A1Z7K8 AIMP1 PTHR11586:SF48 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER AARS-INTERACTING MULTIFUNCTIONAL PROTEIN 1 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 translational protein#PC00263 DROME|FlyBase=FBgn0030597|UniProtKB=Q9VY01 Q9VY01 Eo PTHR11552:SF229 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE ECDYSONE OXIDASE-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036153|UniProtKB=Q8MS56 Q8MS56 Dmel\CG7573 PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 metalloprotease#PC00153 DROME|FlyBase=FBgn0041183|UniProtKB=Q9NFV8 Q9NFV8 Tep1 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 extracellular region#GO:0005576;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0031610|UniProtKB=Q9VR05 Q9VR05 Paris PTHR24390:SF278 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 772 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0004050|UniProtKB=P09956 P09956 z PTHR31535:SF3 FAMILY NOT NAMED REGULATORY PROTEIN ZESTE DROME|FlyBase=FBgn0010358|UniProtKB=C0HKA2 C0HKA2 deltaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031866|UniProtKB=Q9NGK5 Q9NGK5 Nlg2 PTHR43903:SF27 NEUROLIGIN FI21425P1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 transport#GO:0006810;synaptic vesicle cycle#GO:0099504;developmental process#GO:0032502;establishment of localization#GO:0051234;biological regulation#GO:0065007;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;chemical synaptic transmission#GO:0007268;synaptic vesicle endocytosis#GO:0048488;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;postsynapse organization#GO:0099173;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular component assembly#GO:0022607;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;signaling#GO:0023052;synapse assembly#GO:0007416;endocytosis#GO:0006897 plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell surface#GO:0009986;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0039528|UniProtKB=Q9VB20 Q9VB20 dsd PTHR46376:SF2 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 DISTRACTED, ISOFORM B DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0039860|UniProtKB=Q9V9V8 Q9V9V8 Dmel\CG1792 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0027843|UniProtKB=Q9VTU8 Q9VTU8 CAH2 PTHR18952:SF124 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 7 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0033687|UniProtKB=A1Z8T9 A1Z8T9 Dmel\CG8407 PTHR11886:SF2 DYNEIN LIGHT CHAIN DYNEIN AXONEMAL LIGHT CHAIN 4 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0036773|UniProtKB=Q9VVN1 Q9VVN1 Dmel\CG13698 PTHR10671:SF116 EPITHELIAL MEMBRANE PROTEIN-RELATED GH19567P membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0026722|UniProtKB=Q7KNF1 Q7KNF1 drosha PTHR11207:SF37 RIBONUCLEASE III RIBONUCLEASE 3 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;RNA binding#GO:0003723;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;primary miRNA processing#GO:0031053;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;endoribonuclease#PC00094 DROME|FlyBase=FBgn0050489|UniProtKB=P82712 P82712 Cyp12d1-p PTHR24305:SF238 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0259482|UniProtKB=Q9VL13 Q9VL13 Mob3 PTHR22599:SF11 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR-LIKE 3 kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase activator#PC00138 DROME|FlyBase=FBgn0052029|UniProtKB=Q9VSN3 Q9VSN3 Cpr66D PTHR12236:SF18 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 66D cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0020309|UniProtKB=O61360 O61360 crol PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0263027|UniProtKB=Q9VM54 Q9VM54 Dmel\CG43322 PTHR39158:SF1 OS08G0560600 PROTEIN DNAJ HEAT SHOCK PROTEIN FAMILY (HSP40) MEMBER C28 DROME|FlyBase=FBgn0034824|UniProtKB=Q9W1U4 Q9W1U4 Klp59C PTHR24115:SF0 KINESIN-RELATED FI21273P1-RELATED cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0034994|UniProtKB=Q9W191 Q9W191 Ir60a PTHR42643:SF43 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 60A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0035155|UniProtKB=M9PE35 M9PE35 RabX6 PTHR24073:SF1249 DRAB5-RELATED RABX6, ISOFORM B catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein transport#GO:0015031;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 small GTPase#PC00208;G-protein#PC00020 DROME|FlyBase=FBgn0037684|UniProtKB=Q9VHF0 Q9VHF0 Srr PTHR48078:SF19 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE DEAMINASE lyase activity#GO:0016829;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 dehydratase#PC00091;lyase#PC00144 Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995 DROME|FlyBase=FBgn0082585|UniProtKB=Q961J0 Q961J0 sprt PTHR12573:SF4 AT09986P-RELATED AT09986P-RELATED DROME|FlyBase=FBgn0019952|UniProtKB=Q9VCA2 Q9VCA2 Orct PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0028406|UniProtKB=Q9V3H0 Q9V3H0 Drep4 PTHR13067:SF2 CASPASE-ACTIVATED DNASE DNAATION FACTOR-RELATED PROTEIN 4 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;catabolic process#GO:0009056 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>CAD#P00618 DROME|FlyBase=FBgn0015032|UniProtKB=Q9VA27 Q9VA27 Cyp4c3 PTHR24291:SF213 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4C3-RELATED metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0053247|UniProtKB=Q7KV23 Q7KV23 Ste:CG33247 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0003124|UniProtKB=P52304 P52304 polo PTHR24345:SF93 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987 membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0000150|UniProtKB=P08879 P08879 awd PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776 phosphorus metabolic process#GO:0006793;nucleoside triphosphate biosynthetic process#GO:0009142;metabolic process#GO:0008152;cellular process#GO:0009987;nucleoside triphosphate metabolic process#GO:0009141;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 DROME|FlyBase=FBgn0001199|UniProtKB=P02299 P02299 His3 PTHR11426:SF265 HISTONE H3 HISTONE H3.2 mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 DROME|FlyBase=FBgn0001128|UniProtKB=P13706 P13706 Gpdh1 PTHR11728:SF8 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0036332|UniProtKB=Q9VU33 Q9VU33 Cul6 PTHR11932:SF168 CULLIN CULLIN-1 enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198;protein binding#GO:0005515 modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Cul-1#P01239 DROME|FlyBase=FBgn0259219|UniProtKB=B7YZE5 B7YZE5 CG17041 PTHR24214:SF38 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN ZASP-RELATED protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;developmental process#GO:0032502;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;actomyosin#GO:0042641;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;stress fiber#GO:0001725;actin filament#GO:0005884 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0261854|UniProtKB=A1Z9X0 A1Z9X0 aPKC PTHR24356:SF303 SERINE/THREONINE-PROTEIN KINASE ATYPICAL PROTEIN KINASE C catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;establishment or maintenance of cell polarity#GO:0007163;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;macromolecule localization#GO:0033036 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>PKC#P00648;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Endothelin signaling pathway#P00019>PKC#P00568;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 DROME|FlyBase=FBgn0035337|UniProtKB=Q9W019 Q9W019 Dmel\CG15877 PTHR22306:SF2 CHROMOSOME 7 OPEN READING FRAME 50 PROTEIN CHOLESIN DROME|FlyBase=FBgn0287209|UniProtKB=Q7PLC7 Q7PLC7 Gfat1 PTHR10937:SF0 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING) catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;UDP-N-acetylglucosamine biosynthetic process#GO:0006048 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 DROME|FlyBase=FBgn0038014|UniProtKB=Q9VGA5 Q9VGA5 Dmel\CG10041 PTHR24258:SF147 SERINE PROTEASE-RELATED FI16631P1-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0261532|UniProtKB=Q9VEC5 Q9VEC5 cdm PTHR12363:SF33 TRANSPORTIN 3 AND IMPORTIN 13 IMPORTIN-13 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 DROME|FlyBase=FBgn0011656|UniProtKB=P40791 P40791 Mef2 PTHR11945:SF866 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2 nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;histone deacetylase binding#GO:0042826;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 DROME|FlyBase=FBgn0010482|UniProtKB=E1JGY6 E1JGY6 hlk PTHR19991:SF3 L 2 01289 HULK, ISOFORM F DROME|FlyBase=FBgn0001323|UniProtKB=P13054 P13054 knrl PTHR48092:SF9 KNIRPS-RELATED PROTEIN-RELATED KNIRPS-RELATED PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 DROME|FlyBase=FBgn0051759|UniProtKB=Q8IP91 Q8IP91 d3635 PTHR12121:SF37 CARBON CATABOLITE REPRESSOR PROTEIN 4 2',5'-PHOSPHODIESTERASE 12 RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0033547|UniProtKB=Q7JW07 Q7JW07 Dmel\CG12935 PTHR14549:SF2 TRANSMEMBRANE PROTEIN 223 TRANSMEMBRANE PROTEIN 223 DROME|FlyBase=FBgn0037723|UniProtKB=Q9VHA1 Q9VHA1 SpdS PTHR11558:SF11 SPERMIDINE/SPERMINE SYNTHASE SPERMIDINE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220 DROME|FlyBase=FBgn0011693|UniProtKB=Q9VV42 Q9VV42 Pdh PTHR44229:SF8 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] ALCOHOL DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0032022|UniProtKB=Q9VLP1 Q9VLP1 Dmel\CG14275 PTHR33562:SF23 ATILLA, ISOFORM B-RELATED-RELATED GEO08095P1 DROME|FlyBase=FBgn0010441|UniProtKB=Q05652 Q05652 pll PTHR24419:SF39 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE PELLE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;lipopolysaccharide-mediated signaling pathway#GO:0031663;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;response to other organism#GO:0051707;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to peptide#GO:1901652;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Toll pathway-drosophila#P06217>PLL#P06338 DROME|FlyBase=FBgn0033812|UniProtKB=Q7JRD4 Q7JRD4 Pex13 PTHR19332:SF1 PEROXISOMAL MEMBRANE PROTEIN PEX13 PEROXISOMAL MEMBRANE PROTEIN PEX13 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;cellular component organization#GO:0016043;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;peroxisomal transport#GO:0043574;peroxisome organization#GO:0007031 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peroxisomal membrane#GO:0005778;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0001308|UniProtKB=P17210 P17210 Khc PTHR24115:SF1025 KINESIN-RELATED KINESIN HEAVY CHAIN plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 anterograde axonal transport#GO:0008089;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;axonal transport#GO:0098930;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088;synaptic vesicle transport#GO:0048489 microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0034351|UniProtKB=Q7JUX9 Q7JUX9 rswl PTHR13563:SF5 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG C nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;mitochondrial RNA metabolic process#GO:0000959;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;mitochondrion#GO:0005739;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0030816|UniProtKB=Q9VX84 Q9VX84 Dmel\CG16700 PTHR22950:SF150 AMINO ACID TRANSPORTER FI17861P1 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0000277|UniProtKB=C0HKQ8 C0HKQ8 CecA2 PTHR38329:SF1 CECROPIN-A1-RELATED CECROPIN-A1-RELATED defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response#GO:0006952;response to external stimulus#GO:0009605;antibacterial humoral response#GO:0019731;defense response to Gram-positive bacterium#GO:0050830;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0031603|UniProtKB=Q9VQZ5 Q9VQZ5 Dmel\CG15432 PTHR13282:SF6 PROTEIN FAM32A PROTEIN FAM32A intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0028663|UniProtKB=Q9VP18 Q9VP18 VhaM9.7-b PTHR12263:SF0 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600 vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0039689|UniProtKB=Q9VAI1 Q9VAI1 NdufAF1 PTHR13194:SF18 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0259964|UniProtKB=E1JHG2 E1JHG2 Sfp33A3 PTHR21131:SF0 SERINE-TYPE ENDOPEPTIDASE INHIBITOR GEO10195P1-RELATED protease inhibitor#PC00191 DROME|FlyBase=FBgn0031536|UniProtKB=Q961G1 Q961G1 Cog3 PTHR13302:SF8 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;retrograde transport, vesicle recycling within Golgi#GO:0000301;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891 organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;COG complex#GO:0017119;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0030648|UniProtKB=Q9VXU3 Q9VXU3 Dmel\CG6340 PTHR22426:SF2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 DROME|FlyBase=FBgn0031853|UniProtKB=Q9VM92 Q9VM92 TTLL3B PTHR45870:SF11 TUBULIN MONOGLYCYLASE TTLL3 TUBULIN MONOGLYCYLASE TTLL3 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096 developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;gamete generation#GO:0007276;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729 DROME|FlyBase=FBgn0287585|UniProtKB=Q9VPD3 Q9VPD3 Pss PTHR15362:SF15 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 1 transferase#PC00220 DROME|FlyBase=FBgn0024177|UniProtKB=Q9VRX6 Q9VRX6 zpg PTHR11893:SF43 INNEXIN INNEXIN INX4-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cell communication#GO:0007154;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;cellular response to stimulus#GO:0051716;response to radiation#GO:0009314;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 gap junction#PC00105 DROME|FlyBase=FBgn0265998|UniProtKB=P49762 P49762 Doa PTHR45646:SF11 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED SERINE_THREONINE-PROTEIN KINASE DOA phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0265186|UniProtKB=Q7JR80 Q7JR80 CG3884 PTHR31649:SF10 AGAP009604-PA IP19903P-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0035661|UniProtKB=Q9VRS3 Q9VRS3 anon-WO0140519.232 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0050349|UniProtKB=A1Z7K2 A1Z7K2 CG2396 PTHR44267:SF1 WD REPEAT-CONTAINING PROTEIN 43 WD REPEAT-CONTAINING PROTEIN 43 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0029642|UniProtKB=Q9W4U9 Q9W4U9 frag7 PTHR15422:SF45 OS05G0565100 PROTEIN ASCORBATE FERRIREDUCTASE (TRANSMEMBRANE) DROME|FlyBase=FBgn0035986|UniProtKB=Q9VSY1 Q9VSY1 Dmel\CG4022 PTHR22997:SF12 PIH1 DOMAIN-CONTAINING PROTEIN 1 LD09868P-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0004897|UniProtKB=P32028 P32028 fd96Ca PTHR11829:SF377 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD4-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0038880|UniProtKB=Q8IN35 Q8IN35 SIFaR PTHR24241:SF200 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE SIFAMIDE RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030947|UniProtKB=Q9VWR6 Q9VWR6 Dmel\CG6696 PTHR10127:SF905 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0036340|UniProtKB=Q9VU43 Q9VU43 Srrm1 PTHR23148:SF0 SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA processing factor#PC00147 DROME|FlyBase=FBgn0034176|UniProtKB=Q7K172 Q7K172 ste24a PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 metalloprotease#PC00153 DROME|FlyBase=FBgn0011227|UniProtKB=Q9XY35 Q9XY35 ox PTHR12980:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX, SUBUNIT X CYTOCHROME B-C1 COMPLEX SUBUNIT 9 mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646 cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0034797|UniProtKB=Q9W1X5 Q9W1X5 nahoda PTHR46901:SF2 GH04942P GH04942P DROME|FlyBase=FBgn0032863|UniProtKB=Q9I7L8 Q9I7L8 Cdc23 PTHR12558:SF10 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 23 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome separation#GO:1905818;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;positive regulation of cellular component organization#GO:0051130;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;positive regulation of cell cycle process#GO:0090068;regulation of organelle organization#GO:0033043;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;cell division#GO:0051301 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0002774|UniProtKB=P24785 P24785 mle PTHR18934:SF119 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE A ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;helicase activity#GO:0004386 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0038371|UniProtKB=Q9VF25 Q9VF25 Pbp45 PTHR15131:SF3 SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 snRNA transcription by RNA polymerase III#GO:0042796;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;snRNA transcription#GO:0009301;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0260401|UniProtKB=A1ZB42 A1ZB42 MED9 PTHR20844:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0067861|UniProtKB=Q9W5W4 Q9W5W4 Sdic1 PTHR12442:SF22 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED binding#GO:0005488;protein binding#GO:0005515 intracellular transport#GO:0046907;transport#GO:0006810;microtubule-based transport#GO:0099111;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based process#GO:0007017;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;microtubule-based movement#GO:0007018;cytoskeleton-dependent intracellular transport#GO:0030705 cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0002569|UniProtKB=P07191 P07191 Mal-A2 PTHR10357:SF234 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A2-RELATED metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;primary metabolic process#GO:0044238;cellular process#GO:0009987;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975 metabolite interconversion enzyme#PC00262;amylase#PC00048 DROME|FlyBase=FBgn0015615|UniProtKB=Q9VXE9 Q9VXE9 SMC3 PTHR43977:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 DROME|FlyBase=FBgn0261395|UniProtKB=Q9VA12 Q9VA12 Prosalpha3T PTHR11599:SF13 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-4 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0034674|UniProtKB=Q9W2B3 Q9W2B3 Dmel\CG9304 PTHR23252:SF43 INTIMAL THICKNESS RECEPTOR-RELATED GPR180_TMEM145 TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0038811|UniProtKB=E1JIR1 E1JIR1 Pus1 PTHR11142:SF4 PSEUDOURIDYLATE SYNTHASE PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;tRNA modification#GO:0006400;pseudouridine synthesis#GO:0001522;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 lyase#PC00144 DROME|FlyBase=FBgn0033528|UniProtKB=Q7JVK6 Q7JVK6 trsn PTHR10741:SF2 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0261279|UniProtKB=Q8IN05 Q8IN05 lqfR PTHR12276:SF126 EPSIN/ENT-RELATED CLATHRIN INTERACTOR 1 clathrin binding#GO:0030276;binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein binding#GO:0005515 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;vesicle coat#GO:0030120;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;endosome#GO:0005768;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0014006|UniProtKB=Q9VDS9 Q9VDS9 Ask1 PTHR11584:SF369 SERINE/THREONINE PROTEIN KINASE APOPTOTIC SIGNAL-REGULATING KINASE 1, ISOFORM C catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;p38MAPK cascade#GO:0038066;regulation of cellular process#GO:0050794;JNK cascade#GO:0007254;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MEKK1-5#P00553;FGF signaling pathway#P00021>MEKK1-5#P00634 DROME|FlyBase=FBgn0013718|UniProtKB=M9ND89 M9ND89 nuf PTHR15726:SF7 RAB11-FAMILY INTERACTING PROTEIN NUCLEAR FALLOUT, ISOFORM J regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;regulation of biological process#GO:0050789;endocytic recycling#GO:0032456;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 recycling endosome#GO:0055037;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;cleavage furrow#GO:0032154;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;cell division site#GO:0032153;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;midbody#GO:0030496;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0032522|UniProtKB=Q9VJY1 Q9VJY1 Flad2 PTHR23293:SF9 FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE BIFUNCTIONAL FAD DIPHOSPHATASE_FAD SYNTHASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;flavin-containing compound metabolic process#GO:0042726;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 metabolite interconversion enzyme#PC00262;transferase#PC00220 Flavin biosynthesis#P02741>FAD synthetase#P02936 DROME|FlyBase=FBgn0039429|UniProtKB=Q9VBE7 Q9VBE7 Dmel\CG14238 PTHR22168:SF8 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26 DROME|FlyBase=FBgn0002723|UniProtKB=Q9VYW2 Q9VYW2 Met PTHR23042:SF107 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS FI10506P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0053988|UniProtKB=Q9I7V0 Q9I7V0 Mid1 PTHR15819:SF11 TRANSMEMBRANE PROTEIN FAM155 MID1, ISOFORM A transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 inorganic cation import across plasma membrane#GO:0098659;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;transport#GO:0006810;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0031357|UniProtKB=Q9VQ35 Q9VQ35 mRpL48 PTHR13473:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L48 LARGE RIBOSOMAL SUBUNIT PROTEIN ML48 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0031023|UniProtKB=Q9VWH5 Q9VWH5 Dmel\CG14200 PTHR36562:SF5 SERINE/ARGININE REPETITIVE MATRIX 2 SERINE_ARGININE REPETITIVE MATRIX 2 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0261020|UniProtKB=Q9VLQ1 Q9VLQ1 wol PTHR10859:SF91 GLYCOSYL TRANSFERASE DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0040799|UniProtKB=Q6IL42 Q6IL42 Dmel\CG13051 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0037566|UniProtKB=Q9VHT5 Q9VHT5 mRpL1 PTHR36427:SF5 54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0259233|UniProtKB=Q9VC42 Q9VC42 CG13632 PTHR11475:SF4 OXIDASE/PEROXIDASE PEROXINECTIN A peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0259108|UniProtKB=Q9W596 Q9W596 futsch PTHR13843:SF12 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN FUTSCH binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;regulation of microtubule-based process#GO:0032886;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon development#GO:0061564;cellular developmental process#GO:0048869;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;dendrite development#GO:0016358;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;neuron projection#GO:0043005;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cell body#GO:0044297;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037936|UniProtKB=Q9VGJ6 Q9VGJ6 Dmel\CG6908 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0031381|UniProtKB=Q9VQ62 Q9VQ62 Npc2a PTHR11306:SF0 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED LP08842P-RELATED sterol binding#GO:0032934;binding#GO:0005488;steroid binding#GO:0005496;lipid binding#GO:0008289 lipid transport#GO:0006869;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876 DROME|FlyBase=FBgn0053281|UniProtKB=Q8IPZ9 Q8IPZ9 CG15407 PTHR48021:SF33 FAMILY NOT NAMED AT22075P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0032144|UniProtKB=Q9VL86 Q9VL86 CG17633 PTHR11705:SF156 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B RH39904P-RELATED metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0028381|UniProtKB=Q9VET9 Q9VET9 Decay PTHR10454:SF251 CASPASE AT03047P-RELATED catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;biological regulation#GO:0065007;programmed cell death#GO:0012501;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 FAS signaling pathway#P00020>Pro-Caspase6#P00607;FAS signaling pathway#P00020>Caspase6#P00596 DROME|FlyBase=FBgn0039946|UniProtKB=Q86P48 Q86P48 ATbp PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0036427|UniProtKB=Q9VUF0 Q9VUF0 SP40 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0262366|UniProtKB=M9ND79 M9ND79 Dmel\CG43064 PTHR12904:SF32 FAMILY NOT NAMED FI05230P DROME|FlyBase=FBgn0032050|UniProtKB=Q9VLK2 Q9VLK2 CG13096 PTHR48162:SF1 YALI0A06930P RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN CG13096 DROME|FlyBase=FBgn0085438|UniProtKB=A8JPF3 A8JPF3 CG12949 PTHR24260:SF135 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED DROME|FlyBase=FBgn0265191|UniProtKB=A0A0B4LFW5 A0A0B4LFW5 Gyg PTHR11183:SF204 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0045064|UniProtKB=Q9VIP7 Q9VIP7 bwa PTHR46139:SF3 ALKALINE CERAMIDASE ALKALINE CERAMIDASE lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;ceramide metabolic process#GO:0006672 DROME|FlyBase=FBgn0034389|UniProtKB=A1ZBD6 A1ZBD6 Mctp PTHR45911:SF10 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of biological process#GO:0050789;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of neurotransmitter secretion#GO:0046928;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0034154|UniProtKB=A1ZAJ3 A1ZAJ3 Dmel\CG5267 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0000611|UniProtKB=P40427 P40427 exd PTHR11850:SF108 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN EXTRADENTICLE DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 positive regulation of RNA metabolic process#GO:0051254;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;embryonic organ development#GO:0048568;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0083979|UniProtKB=A8JUR3 A8JUR3 Ir10a PTHR42643:SF48 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 100A transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0026261|UniProtKB=Q8WTC1 Q8WTC1 bonsai PTHR46685:SF1 28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US15M cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0051642|UniProtKB=Q8IPJ9 Q8IPJ9 CG5981 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0262126|UniProtKB=M9PC99 M9PC99 Sec24CD PTHR13803:SF4 SEC24-RELATED PROTEIN SECRETORY 24CD, ISOFORM C cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;SNARE binding#GO:0000149 cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0033692|UniProtKB=Q7JW27 Q7JW27 wash PTHR23331:SF1 CXYORF1 WASH COMPLEX SUBUNIT 1 localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;supramolecular fiber organization#GO:0097435;secretion by cell#GO:0032940;localization within membrane#GO:0051668;actin filament-based process#GO:0030029;endocytic recycling#GO:0032456;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;export from cell#GO:0140352;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;exocytosis#GO:0006887;actin filament organization#GO:0007015;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987 endosome#GO:0005768;intracellular organelle#GO:0043229;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0015316|UniProtKB=Q9VLF5 Q9VLF5 Try29F PTHR24276:SF97 POLYSERASE-RELATED GH13245P2-RELATED catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0033229|UniProtKB=A1Z759 A1Z759 CG12822-PA PTHR12818:SF0 TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 DROME|FlyBase=FBgn0039130|UniProtKB=Q9VCF8 Q9VCF8 Dmel\CG5854 PTHR43245:SF11 BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA LD23561P DROME|FlyBase=FBgn0000581|UniProtKB=A0A0B4KFP2 A0A0B4KFP2 E(Pc) PTHR14898:SF0 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB-LIKE PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0260390|UniProtKB=E1JH07 E1JH07 Dmel\CG42516 PTHR21860:SF2 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 6-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 6 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 transcription factor TFIIIC complex#GO:0000127;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DROME|FlyBase=FBgn0259140|UniProtKB=Q9VTP0 Q9VTP0 Cubn2 PTHR46908:SF8 CUBILIN-LIKE PROTEIN CUBILIN 2 DROME|FlyBase=FBgn0039291|UniProtKB=Q9VBW0 Q9VBW0 Saysd1 PTHR13527:SF0 SAYSVFN DOMAIN-CONTAINING PROTEIN 1 SAYSVFN DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule catabolic process#GO:0009057;translational elongation#GO:0006414;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rescue of stalled cytosolic ribosome#GO:0072344;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein biosynthetic process#GO:0160307;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;translation#GO:0006412;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0028683|UniProtKB=Q9TVQ5 Q9TVQ5 spt4 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0010042|UniProtKB=Q9VG94 Q9VG94 GstD6 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0029783|UniProtKB=Q8IRR5 Q8IRR5 Sirt4 PTHR11085:SF20 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN LIPOAMIDASE SIRTUIN-4, MITOCHONDRIAL transferase activity#GO:0016740;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0033570|UniProtKB=Q7JZK1 Q7JZK1 ND-B14 PTHR12964:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6 membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 DROME|FlyBase=FBgn0037031|UniProtKB=Q9VPA2 Q9VPA2 Dmel\CG11456 PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0035593|UniProtKB=Q9VRJ9 Q9VRJ9 Yod1 PTHR13312:SF0 HIV-INDUCED PROTEIN-7-LIKE PROTEASE UBIQUITIN THIOESTERASE OTU1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0039784|UniProtKB=Q9VA60 Q9VA60 Dmel\CG9698 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031441|UniProtKB=Q9VQE3 Q9VQE3 Dmel\CG9962 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 DROME|FlyBase=FBgn0000276|UniProtKB=C0HKQ7 C0HKQ7 CecA1 PTHR38329:SF1 CECROPIN-A1-RELATED CECROPIN-A1-RELATED response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;defense response to Gram-positive bacterium#GO:0050830;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;antibacterial humoral response#GO:0019731;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0004859|UniProtKB=P19538 P19538 ci PTHR45718:SF4 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690;Hedgehog signaling pathway#P00025>Cubitus interruptus repressor#P00687 DROME|FlyBase=FBgn0038051|UniProtKB=Q7KSM4 Q7KSM4 Dmel\CG17207 PTHR23427:SF1 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 chaperone#PC00072 DROME|FlyBase=FBgn0061362|UniProtKB=A1ZBX4 A1ZBX4 Polr3K PTHR11239:SF12 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on RNA#GO:0140098 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0033644|UniProtKB=Q8MKK4 Q8MKK4 Tret1l PTHR48021:SF104 FAMILY NOT NAMED TREHALOSE TRANSPORTER 1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0260817|UniProtKB=Q9VQM4 Q9VQM4 Tdp1 PTHR12415:SF0 TYROSYL-DNA PHOSPHODIESTERASE 1 TYROSYL-DNA PHOSPHODIESTERASE 1 single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 phosphodiesterase#PC00185 DROME|FlyBase=FBgn0036767|UniProtKB=Q9VVM3 Q9VVM3 Dmel\CG16775 PTHR31649:SF10 AGAP009604-PA IP19903P-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0029873|UniProtKB=Q9W3Z5 Q9W3Z5 Dmel\CG3918 PTHR31437:SF1 SREK1IP1 FAMILY MEMBER PROTEIN SREK1IP1 DROME|FlyBase=FBgn0262127|UniProtKB=Q9VFG8 Q9VFG8 kibra PTHR14791:SF56 BOMB/KIRA PROTEINS PROTEIN KIBRA enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of growth#GO:0040008;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of macromolecule metabolic process#GO:0060255;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of response to stimulus#GO:0048583;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0040398|UniProtKB=Q9W5B4 Q9W5B4 EG:103E12.2 PTHR20997:SF2 EG:BACR42I17.2 PROTEIN-RELATED EG:BACR42I17.2 PROTEIN-RELATED DROME|FlyBase=FBgn0086378|UniProtKB=A8Y589 A8Y589 Alg-2 PTHR46212:SF3 PEFLIN PROGRAMMED CELL DEATH PROTEIN 6 DROME|FlyBase=FBgn0259720|UniProtKB=B7Z073 B7Z073 CG42374 PTHR31526:SF2 SOSS COMPLEX SUBUNIT C SOSS COMPLEX SUBUNIT C macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0032080|UniProtKB=Q9VLG5 Q9VLG5 gi7297470 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0263132|UniProtKB=M9NDS9 M9NDS9 Cht6 PTHR11177:SF399 CHITINASE CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 DROME|FlyBase=FBgn0033205|UniProtKB=A1Z729 A1Z729 Rdh1 PTHR24320:SF294 RETINOL DEHYDROGENASE NADP-RETINOL DEHYDROGENASE-RELATED alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0039225|UniProtKB=Q8MRW5 Q8MRW5 Ets96B PTHR11849:SF282 ETS ETV5-RELATED PROTEIN ETS96B DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0033043|UniProtKB=Q9V9I4 Q9V9I4 Or42b PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0000022|UniProtKB=P10083 P10083 ac PTHR13935:SF169 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE COMPLEX PROTEIN T5-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0022986|UniProtKB=Q9W255 Q9W255 qkr58E-1 PTHR11208:SF140 RNA-BINDING PROTEIN RELATED GH05812P-RELATED mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0038734|UniProtKB=Q9VDU0 Q9VDU0 Acsx4 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;organophosphate biosynthetic process#GO:0090407;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;fatty acid metabolic process#GO:0006631 ligase#PC00142 DROME|FlyBase=FBgn0040465|UniProtKB=Q7JZD5 Q7JZD5 Dlip3 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0038147|UniProtKB=Q8SXL2 Q8SXL2 CCHa2 PTHR35980:SF1 NEUROPEPTIDE CCHAMIDE-1-RELATED NEUROPEPTIDE CCHAMIDE-1-RELATED DROME|FlyBase=FBgn0250833|UniProtKB=Q5U126 Q5U126 CG7072 PTHR12236:SF75 STRUCTURAL CONSTITUENT OF CUTICLE GEO11286P1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0052488|UniProtKB=Q8SXC9 Q8SXC9 CG2077 PTHR19288:SF93 4-NITROPHENYLPHOSPHATASE-RELATED FI11325P-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0261794|UniProtKB=A0A0B4LGD3 A0A0B4LGD3 kcc PTHR11827:SF73 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS KAZACHOC, ISOFORM G symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride transmembrane transporter activity#GO:0015108;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0035046|UniProtKB=Q9W125 Q9W125 ND-19 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0031695|UniProtKB=Q9VMS7 Q9VMS7 Cyp4ac3 PTHR24291:SF105 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4P1-RELATED oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 DROME|FlyBase=FBgn0000259|UniProtKB=P08182 P08182 CkIIbeta PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;serine/threonine protein kinase complex#GO:1902554;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0036939|UniProtKB=Q9VW80 Q9VW80 Dmel\CG7365 PTHR21325:SF31 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED phospholipase#PC00186 DROME|FlyBase=FBgn0039907|UniProtKB=Q961D9 Q961D9 lgs PTHR23194:SF17 PYGOPUS PROTEIN BCL9 HOMOLOG transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0053631|UniProtKB=Q4AB37 Q4AB37 Dmel\CG33631 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0021825|UniProtKB=Q7K2D2 Q7K2D2 DCTN2-p50 PTHR15346:SF0 DYNACTIN SUBUNIT DYNACTIN SUBUNIT 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093;protein-membrane adaptor activity#GO:0043495 microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;nuclear migration#GO:0007097;microtubule-based movement#GO:0007018;mitotic spindle organization#GO:0007052;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629 microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0032495|UniProtKB=Q9VK11 Q9VK11 cg16820 PTHR11008:SF18 PROTEIN TAKEOUT-LIKE PROTEIN BCDNA.GH05536-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0039668|UniProtKB=Q7KRW1 Q7KRW1 Trc8 PTHR22763:SF163 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF139 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0083967|UniProtKB=Q0KI28 Q0KI28 Muted PTHR31784:SF3 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083 DROME|FlyBase=FBgn0036529|UniProtKB=Q9VUT6 Q9VUT6 Pgant8 PTHR11675:SF134 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0261363|UniProtKB=Q9W1V6 Q9W1V6 PPO3 PTHR11511:SF4 LARVAL STORAGE PROTEIN/PHENOLOXIDASE PHENOLOXIDASE 2-RELATED DROME|FlyBase=FBgn0051547|UniProtKB=Q9VNC7 Q9VNC7 NKCC PTHR11827:SF48 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS GH09711P monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108 establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;metal ion transport#GO:0030001;monoatomic anion transport#GO:0006820;sodium ion transport#GO:0006814 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0031032|UniProtKB=Q9VWG6 Q9VWG6 Dmel\CG14204 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0052344|UniProtKB=Q8SY39 Q8SY39 CG6994 PTHR24031:SF292 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX54 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0019809|UniProtKB=Q9VLA2 Q9VLA2 gcm2 PTHR12414:SF8 GLIAL CELLS MISSING RELATED/GLIDE TRANSCRIPTION FACTOR GLIAL CELLS MISSING-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;gliogenesis#GO:0042063;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0033483|UniProtKB=Q8MUJ1 Q8MUJ1 egr PTHR15151:SF24 PROTEIN EIGER TUMOR NECROSIS FACTOR FAMILY MEMBER EIGER signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0267976|UniProtKB=Q8MRW1 Q8MRW1 Tim23 PTHR15371:SF0 TIM23 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM23 transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 transporter#PC00227;amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0038195|UniProtKB=Q9VFP0 Q9VFP0 Dmel\CG3061 PTHR43908:SF3 AT29763P-RELATED AT29763P-RELATED Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular response to misfolded protein#GO:0071218;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;response to stimulus#GO:0050896 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0033135|UniProtKB=Q7JYY8 Q7JYY8 Tsp42En PTHR19282:SF456 TETRASPANIN FI23944P1-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0283509|UniProtKB=O01404 O01404 Phm PTHR10680:SF39 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 DROME|FlyBase=FBgn0038321|UniProtKB=Q9VF86 Q9VF86 Nagk PTHR12862:SF0 BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN N-ACETYL-D-GLUCOSAMINE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 DROME|FlyBase=FBgn0037972|UniProtKB=Q8MYX4 Q8MYX4 Dmel\CG10005 PTHR46560:SF7 CYPHER, ISOFORM B RE59626P developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;anatomical structure development#GO:0048856 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 DROME|FlyBase=FBgn0035827|UniProtKB=Q9VSC1 Q9VSC1 Srp9 PTHR12834:SF12 SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 ribonucleoprotein complex#GO:1990904;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032979|UniProtKB=Q9V9N4 Q9V9N4 Clamp PTHR24381:SF393 ZINC FINGER PROTEIN LD39664P-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0045497|UniProtKB=P58953 P58953 Gr22e PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0035644|UniProtKB=Q9VRQ7 Q9VRQ7 PolE2 PTHR12708:SF0 DNA POLYMERASE EPSILON SUBUNIT B DNA POLYMERASE EPSILON SUBUNIT 2 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;DNA-templated DNA replication#GO:0006261 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018 DROME|FlyBase=FBgn0053687|UniProtKB=Q4ABJ3 Q4ABJ3 Dmel\CG33687 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0050476|UniProtKB=Q8ML92 Q8ML92 ave PTHR20843:SF0 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 PROTEIN AVEUGLE cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 DROME|FlyBase=FBgn0267431|UniProtKB=A0A0A1EI90 A0A0A1EI90 Myo81F PTHR13140:SF561 MYOSIN MIP31562P1 microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;membrane#GO:0016020 actin binding motor protein#PC00040 DROME|FlyBase=FBgn0001187|UniProtKB=Q7JYW9 Q7JYW9 Hex-C PTHR19443:SF16 HEXOKINASE HEXOKINASE-2-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 DROME|FlyBase=FBgn0000629|UniProtKB=P42124 P42124 E(z) PTHR45747:SF21 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;binding#GO:0005488;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;chromatin binding#GO:0003682;histone methyltransferase activity#GO:0042054;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507 nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0264817|UniProtKB=A0A0B4KEI4 A0A0B4KEI4 pre-lola-G PTHR23110:SF116 BTB DOMAIN TRANSCRIPTION FACTOR PROTEIN BRIC-A-BRAC 1-RELATED regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0261675|UniProtKB=Q9VRC9 Q9VRC9 Npc1b PTHR45727:SF6 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 HOMOLOG 1B sterol binding#GO:0032934;small molecule binding#GO:0036094;binding#GO:0005488;cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289;alcohol binding#GO:0043178 multicellular organismal process#GO:0032501;lipid transport#GO:0006869;digestion#GO:0007586;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;macromolecule localization#GO:0033036;sterol transport#GO:0015918;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;localization#GO:0051179;system process#GO:0003008;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;chemical homeostasis#GO:0048878;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0259230|UniProtKB=B7YZU7 B7YZU7 lectin-22C PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0002775|UniProtKB=P50536 P50536 msl-3 PTHR10880:SF55 MORTALITY FACTOR 4-LIKE PROTEIN MSL COMPLEX SUBUNIT 3 histone reader activity#GO:0140566;chromatin binding#GO:0003682;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;chromatin-protein adaptor activity#GO:0140463 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0052196|UniProtKB=Q8IQT0 Q8IQT0 Dmel\CG32196 PTHR12935:SF0 GAMMA-GLUTAMYLCYCLOTRANSFERASE GAMMA-GLUTAMYLCYCLOTRANSFERASE catalytic activity#GO:0003824;lyase activity#GO:0016829 DROME|FlyBase=FBgn0266282|UniProtKB=Q9VCB8 Q9VCB8 SMC6 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0038660|UniProtKB=Q9VE24 Q9VE24 Sgsh PTHR43108:SF6 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-SULPHOGLUCOSAMINE SULPHOHYDROLASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 glycoprotein metabolic process#GO:0009100;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan catabolic process#GO:0006027;protein catabolic process#GO:0030163;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121 DROME|FlyBase=FBgn0033294|UniProtKB=A1Z7E8 A1Z7E8 Mal-A4 PTHR10357:SF235 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A3-RELATED carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;cellular process#GO:0009987;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;amylase#PC00048 DROME|FlyBase=FBgn0036684|UniProtKB=E3CTN7 E3CTN7 CG3764-RA PTHR21634:SF9 RE13835P RE13835P protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0062442|UniProtKB=Q9VAM6 Q9VAM6 Cisd PTHR13680:SF5 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transaminase activity#GO:0008483;iron-sulfur cluster binding#GO:0051536 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 DROME|FlyBase=FBgn0033948|UniProtKB=A1Z9S8 A1Z9S8 Dmel\CG12863 PTHR13493:SF3 ZINC FINGER CCHC DOMAIN-CONTAINING RRNA N(6)-ADENOSINE-METHYLTRANSFERASE ZCCHC4 N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0013531|UniProtKB=P91641 P91641 MED20 PTHR12465:SF0 UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0261283|UniProtKB=Q9VW37 Q9VW37 SREBP PTHR46062:SF1 STEROL REGULATORY ELEMENT-BINDING PROTEIN LP12374P sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0027836|UniProtKB=Q0E931 Q0E931 Gtpbp1 PTHR43721:SF9 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 1 translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412 translation elongation factor#PC00222 DROME|FlyBase=FBgn0250850|UniProtKB=Q86BY9 Q86BY9 rig PTHR46362:SF1 GEM-ASSOCIATED PROTEIN 5 GEM-ASSOCIATED PROTEIN 5 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;Sm-like protein family complex#GO:0120114 DROME|FlyBase=FBgn0033216|UniProtKB=A1Z739 A1Z739 bishu-2 PTHR12317:SF0 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 neutral lipid metabolic process#GO:0006638;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0263397|UniProtKB=A1Z9N7 A1Z9N7 Ih PTHR45689:SF5 I[[H]] CHANNEL, ISOFORM E I[[H]] CHANNEL, ISOFORM E voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0039599|UniProtKB=Q9VAT6 Q9VAT6 intr PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0034770|UniProtKB=Q9W207 Q9W207 Obp58d PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0000551|UniProtKB=P27779 P27779 Edg78E PTHR10380:SF238 CUTICLE PROTEIN CUTICULAR PROTEIN 65EA-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0040010|UniProtKB=M9PGG8 M9PGG8 Dmel\CG17493 PTHR23050:SF549 CALCIUM BINDING PROTEIN AT22559P ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membrane-bounded organelle#GO:0043231;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0037841|UniProtKB=Q9VGW0 Q9VGW0 Dmel\CG4565 PTHR46223:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0037332|UniProtKB=A0A0B4LGM5 A0A0B4LGM5 Hcs PTHR12835:SF5 BIOTIN PROTEIN LIGASE BIOTIN--PROTEIN LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 DROME|FlyBase=FBgn0039774|UniProtKB=Q9VA70 Q9VA70 CDase PTHR12670:SF21 CERAMIDASE NEUTRAL CERAMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;lipid catabolic process#GO:0016042;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;monocarboxylic acid biosynthetic process#GO:0072330 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0054038|UniProtKB=Q2PE11 Q2PE11 BP1023 PTHR36299:SF4 AGAP008005-PA GH07892P-RELATED DROME|FlyBase=FBgn0033434|UniProtKB=Q7K1M4 Q7K1M4 Dmel\CG1902 PTHR10174:SF216 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN-RELATED phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0031675|UniProtKB=Q9VMV0 Q9VMV0 Dmel\CG9121 PTHR24198:SF196 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ZU5 DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0000376|UniProtKB=O76906 O76906 crm PTHR21677:SF1 CRAMPED PROTEIN PROTEIN CRAMPED-LIKE chromatin binding#GO:0003682;binding#GO:0005488 developmental process#GO:0032502;pattern specification process#GO:0007389;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0034457|UniProtKB=A1ZBM8 A1ZBM8 Ir56c PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0035581|UniProtKB=Q9VZ77 Q9VZ77 Dnah3 PTHR10676:SF405 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 3 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;microtubule motor activity#GO:0003777;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657 cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;inner dynein arm assembly#GO:0036159;spermatid differentiation#GO:0048515;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;inner dynein arm#GO:0036156;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494;9+2 motile cilium#GO:0097729;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0051915|UniProtKB=Q8IPK4 Q8IPK4 CG31915 PTHR10730:SF56 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER GLYCOSYLTRANSFERASE 25 FAMILY MEMBER galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0052971|UniProtKB=Q86BK9 Q86BK9 Dmel\CG32971 PTHR12434:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035102|UniProtKB=Q9W0U6 Q9W0U6 Dmel\CG7049 PTHR23150:SF37 SULFATASE MODIFYING FACTOR 1, 2 FORMYLGLYCINE-GENERATING ENZYME oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053703|UniProtKB=Q4ABI8 Q4ABI8 Dmel\CG33703 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0033738|UniProtKB=Q7JQI1 Q7JQI1 DUBAI PTHR24006:SF908 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE DEUBIQUITINATING APOPTOTIC INHIBITOR, ISOFORM A deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0030775|UniProtKB=Q9VXC7 Q9VXC7 Dmel\CG9673 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0004395|UniProtKB=Q86B79 Q86B79 unk PTHR14493:SF87 UNKEMPT FAMILY MEMBER RING FINGER PROTEIN UNKEMPT DROME|FlyBase=FBgn0035769|UniProtKB=Q9VS55 Q9VS55 CTCF PTHR24390:SF148 ZINC FINGER PROTEIN CTCF DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0000152|UniProtKB=O97132 O97132 Axs PTHR12308:SF74 ANOCTAMIN ANOCTAMIN intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128 regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0264077|UniProtKB=Q9VXF6 Q9VXF6 Cnx14D PTHR11073:SF1 CALRETICULIN AND CALNEXIN CALNEXIN 14D-RELATED binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0024947|UniProtKB=M9PBV2 M9PBV2 NTPase PTHR11782:SF127 ADENOSINE/GUANOSINE DIPHOSPHATASE NUCLEOSIDE DIPHOSPHATE PHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787 metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139 membrane#GO:0016020;cellular anatomical structure#GO:0110165 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0040038|UniProtKB=Q6GKZ1 Q6GKZ1 klhl10 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031461|UniProtKB=Q9VQG9 Q9VQG9 daw PTHR11848:SF316 TGF-BETA FAMILY LD29161P-RELATED cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 ALP23B signaling pathway#P06209>ALP23B full length#P06225;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;MYO signaling pathway#P06215>myoglianin full length#P06315;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;TGF-beta signaling pathway#P00052>TGFbeta#P01286;MYO signaling pathway#P06215>myoglianin#P06312;ALP23B signaling pathway#P06209>ALP23B#P06223 DROME|FlyBase=FBgn0031384|UniProtKB=Q9VQ67 Q9VQ67 Dmel\CG4238 PTHR11254:SF340 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE APOPTOSIS-RESISTANT E3 UBIQUITIN PROTEIN LIGASE 1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of apoptotic process#GO:0042981;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0032882|UniProtKB=Q9VIJ9 Q9VIJ9 Ns4 PTHR45709:SF3 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 DROME|FlyBase=FBgn0037922|UniProtKB=Q9VGL2 Q9VGL2 Dmel\CG14711 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0024329|UniProtKB=Q8MSQ4 Q8MSQ4 Mekk1 PTHR48016:SF32 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 4 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;p38MAPK cascade#GO:0038066;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Oxidative stress response#P00046>MKK4#P01138;p38 MAPK pathway#P05918>MEKK4#P06026;FGF signaling pathway#P00021>MEKK1-5#P00634;Integrin signalling pathway#P00034>ERK#P00907;Interleukin signaling pathway#P00036>MEK#P00984;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;Ras Pathway#P04393>MEKK1/4#P04543;PDGF signaling pathway#P00047>ERK#P01143;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 DROME|FlyBase=FBgn0033915|UniProtKB=Q0E981 Q0E981 Snrk PTHR24343:SF181 SERINE/THREONINE KINASE SNF-RELATED SERINE_THREONINE-PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031082|UniProtKB=Q9W5X9 Q9W5X9 lky PTHR12327:SF0 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 DROME|FlyBase=FBgn0031229|UniProtKB=Q9VPL0 Q9VPL0 Dmel\CG3436 PTHR44006:SF1 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 mRNA splicing#P00058>U5#P01474 DROME|FlyBase=FBgn0265726|UniProtKB=Q9VY99 Q9VY99 Nna1 PTHR12756:SF47 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE NNA1 binding#GO:0005488;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;protein binding#GO:0005515;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;tubulin binding#GO:0015631;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 DROME|FlyBase=FBgn0037718|UniProtKB=Q9VHA8 Q9VHA8 P58IPK PTHR44140:SF2 LD25575P LD25575P protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0005636|UniProtKB=A0A0B4KEZ2 A0A0B4KEZ2 nvy PTHR10379:SF14 MTG8 ETO EIGHT TWENTY ONE PROTEIN NERVY, ISOFORM D transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0003980|UniProtKB=P13238 P13238 Vm26Ab PTHR47641:SF14 PERIAXIN-LIKE GOLGI-ASSOCIATED OLFACTORY SIGNALING REGULATOR DROME|FlyBase=FBgn0032407|UniProtKB=Q8IP97 Q8IP97 Pex19 PTHR12774:SF2 PEROXISOMAL BIOGENESIS FACTOR 19 PEROXISOMAL BIOGENESIS FACTOR 19 signal sequence receptor activity#GO:0005048 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein transport#GO:0015031;peroxisomal transport#GO:0043574;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;peroxisome organization#GO:0007031;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0038073|UniProtKB=Q9VG43 Q9VG43 Dmel\CG14395 PTHR21219:SF4 FI19613P1 PID DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0268063|UniProtKB=Q9VS84 Q9VS84 ltl PTHR24373:SF418 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN FI03225P signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0001123|UniProtKB=P20354 P20354 Galphas PTHR10218:SF212 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA S SUBUNIT hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 response to nitrogen compound#GO:1901698;cell communication#GO:0007154;sensory perception#GO:0007600;response to oxygen-containing compound#GO:1901700;nervous system process#GO:0050877;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212 cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 G-protein#PC00020;heterotrimeric G-protein#PC00117 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977 DROME|FlyBase=FBgn0013467|UniProtKB=Q7JPS2 Q7JPS2 igl PTHR10699:SF11 NEUROMODULIN IGLOO, ISOFORM A protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 DROME|FlyBase=FBgn0011829|UniProtKB=Q7KT06 Q7KT06 Ret PTHR24416:SF660 TYROSINE-PROTEIN KINASE RECEPTOR RET ONCOGENE, ISOFORM A transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036962|UniProtKB=Q9VWA6 Q9VWA6 Dmel\CG17122 PTHR31954:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229 structural protein#PC00211 DROME|FlyBase=FBgn0000382|UniProtKB=P29349 P29349 csw PTHR46257:SF3 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE CORKSCREW catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488 cell cycle#GO:0007049;cellular process#GO:0009987;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Interferon-gamma signaling pathway#P00035>PTP#P00960;FGF signaling pathway#P00021>SHP2#P00647 DROME|FlyBase=FBgn0036725|UniProtKB=Q9VVH2 Q9VVH2 ORE-10 PTHR21190:SF1 GH10077P GH10077P DROME|FlyBase=FBgn0026199|UniProtKB=Q9V4F4 Q9V4F4 myo PTHR11848:SF316 TGF-BETA FAMILY LD29161P-RELATED molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 ALP23B signaling pathway#P06209>ALP23B full length#P06225;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;MYO signaling pathway#P06215>myoglianin full length#P06315;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;TGF-beta signaling pathway#P00052>TGFbeta#P01286;MYO signaling pathway#P06215>myoglianin#P06312;ALP23B signaling pathway#P06209>ALP23B#P06223 DROME|FlyBase=FBgn0038234|UniProtKB=Q9VFJ2 Q9VFJ2 mRpL11 PTHR11661:SF48 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 DROME|FlyBase=FBgn0263988|UniProtKB=Q9W0U9 Q9W0U9 Dic61B PTHR12442:SF12 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 4 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987;cilium movement#GO:0003341 axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0051935|UniProtKB=Q9VQ26 Q9VQ26 Rab3GAP1 PTHR21422:SF9 RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of cellular component biogenesis#GO:0044087;positive regulation of macroautophagy#GO:0016239;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;positive regulation of cellular component organization#GO:0051130;regulation of autophagosome assembly#GO:2000785;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of autophagy#GO:0010508;regulation of catabolic process#GO:0009894;regulation of macroautophagy#GO:0016241;positive regulation of catabolic process#GO:0009896 G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0039718|UniProtKB=Q9VAE6 Q9VAE6 Dmel\CG15517 PTHR36299:SF1 AGAP008005-PA DUF4773 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0028507|UniProtKB=M9NF32 M9NF32 BG:DS09217.4 PTHR13600:SF33 LEUCINE CARBOXYL METHYLTRANSFERASE LEUCINE CARBOXYL METHYLTRANSFERASE 1 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of sister chromatid segregation#GO:0033045;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;regulation of response to stimulus#GO:0048583;regulation of chromosome segregation#GO:0051983;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of chromosome separation#GO:1905818;regulation of nuclear division#GO:0051783;regulation of signal transduction#GO:0009966;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 DROME|FlyBase=FBgn0003358|UniProtKB=P17207 P17207 Jon99Ci PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0038246|UniProtKB=Q9VFH8 Q9VFH8 Dmel\CG14853 PTHR21520:SF2 GLUTAMATE-RICH PROTEIN 2 GLUTAMATE-RICH PROTEIN 2 DROME|FlyBase=FBgn0261850|UniProtKB=Q7KVP9 Q7KVP9 Xpd PTHR11472:SF1 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;damaged DNA binding#GO:0003684;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA helicase#PC00011 DROME|FlyBase=FBgn0052302|UniProtKB=Q9W030 Q9W030 CG13805 PTHR23301:SF115 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0040751|UniProtKB=Q4V429 Q4V429 Dmel\CG13018 PTHR28627:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0047178|UniProtKB=Q8SZB7 Q8SZB7 Dmel\CG32147 PTHR23402:SF1 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED RE07960P hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cysteine protease#PC00081 DROME|FlyBase=FBgn0265630|UniProtKB=A8JUV0 A8JUV0 sno PTHR12706:SF30 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH-RELATED DROME|FlyBase=FBgn0038389|UniProtKB=Q9VF05 Q9VF05 Dmel\CG5516 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 DROME|FlyBase=FBgn0028541|UniProtKB=Q9V3N6 Q9V3N6 TM9SF4 PTHR10766:SF188 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 4 cellular process#GO:0009987;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0039140|UniProtKB=Q8IMX7 Q8IMX7 Miro PTHR24072:SF418 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 organelle localization#GO:0051640;actin filament-based process#GO:0030029;localization#GO:0051179;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;cellular response to stimulus#GO:0051716;microtubule-based movement#GO:0007018;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;actin filament organization#GO:0007015;mitochondrion localization#GO:0051646;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of organelle localization#GO:0051656;signaling#GO:0023052;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular process#GO:0009987;mitochondrion organization#GO:0007005;cytoskeleton organization#GO:0007010;organelle transport along microtubule#GO:0072384 organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 small GTPase#PC00208;G-protein#PC00020 DROME|FlyBase=FBgn0032524|UniProtKB=Q9VJX8 Q9VJX8 Hacd2 PTHR11035:SF35 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 dehydratase#PC00091 DROME|FlyBase=FBgn0011758|UniProtKB=Q24255 Q24255 B-H1 PTHR24330:SF10 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN B-H1-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0031600|UniProtKB=Q9VQZ0 Q9VQZ0 Dmel\CG3652 PTHR21236:SF1 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF6 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791 structural protein#PC00211 DROME|FlyBase=FBgn0285879|UniProtKB=Q9VXJ5 Q9VXJ5 disco-r PTHR15021:SF0 DISCONNECTED-RELATED DISCO-RELATED, ISOFORM A-RELATED regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0035948|UniProtKB=Q9VSS3 Q9VSS3 Dmel\CG5644 PTHR11012:SF47 PROTEIN KINASE-LIKE DOMAIN-CONTAINING GH22833P DROME|FlyBase=FBgn0033005|UniProtKB=Q9V9E3 Q9V9E3 CG3107 PTHR43016:SF18 PRESEQUENCE PROTEASE PRESEQUENCE PROTEASE, MITOCHONDRIAL metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 metalloprotease#PC00153 DROME|FlyBase=FBgn0087011|UniProtKB=Q5BIB8 Q5BIB8 CG40067 PTHR19143:SF426 FIBRINOGEN/TENASCIN/ANGIOPOEITIN RE19569P cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0039777|UniProtKB=Q9VA67 Q9VA67 Jon99Fii PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0038608|UniProtKB=Q9VE86 Q9VE86 WRNexo PTHR13620:SF109 3-5 EXONUCLEASE 3'-5' EXONUCLEASE 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;hydrolase activity#GO:0016787;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097 RNA biosynthetic process#GO:0032774;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA repair#GO:0006281 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 DROME|FlyBase=FBgn0036099|UniProtKB=Q9VTB3 Q9VTB3 oya PTHR23117:SF13 GUANYLATE KINASE-RELATED GUANYLATE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776 purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide biosynthetic process#GO:0006164;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;kinase#PC00137 De novo purine biosynthesis#P02738>Guanylate kinase#P02904 DROME|FlyBase=FBgn0031713|UniProtKB=Q9VMQ5 Q9VMQ5 Coq6 PTHR43876:SF7 UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0034763|UniProtKB=Q9W215 Q9W215 RYBP PTHR12920:SF4 RYBP AND YAF2-RELATED GEO03726P1 DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 DROME|FlyBase=FBgn0038273|UniProtKB=Q9VFE8 Q9VFE8 Dmel\CG14860 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0036838|UniProtKB=Q9VVV7 Q9VVV7 Trmt2a PTHR45904:SF2 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0032402|UniProtKB=Q9VKC3 Q9VKC3 PLCXD PTHR13593:SF103 FAMILY NOT NAMED PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C X DOMAIN CONTAINING, ISOFORM A phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 DROME|FlyBase=FBgn0085473|UniProtKB=A8DYD7 A8DYD7 Dmel\CG34444 PTHR21398:SF22 AGAP007094-PA IP12060P-RELATED DROME|FlyBase=FBgn0024319|UniProtKB=O61365 O61365 Nach PTHR11690:SF263 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 6-RELATED passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0024222|UniProtKB=Q9VEZ5 Q9VEZ5 IKKbeta PTHR22969:SF17 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>IKK#P00313 DROME|FlyBase=FBgn0033241|UniProtKB=Q0E9F9 Q0E9F9 Dmel\CG2915 PTHR11705:SF60 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B ZINC CARBOXYPEPTIDASE A 1 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 DROME|FlyBase=FBgn0013680|UniProtKB=P03896 P03896 mt:ND2 PTHR46552:SF1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;NADH dehydrogenase activity#GO:0003954;electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324 generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176 DROME|FlyBase=FBgn0052499|UniProtKB=Q9VR69 Q9VR69 Cda4 PTHR45985:SF3 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 4 DROME|FlyBase=FBgn0086443|UniProtKB=Q9V434 Q9V434 AsnRS PTHR22594:SF16 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0040262|UniProtKB=Q9VJI0 Q9VJI0 Ugt37C2 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0030486|UniProtKB=Q9VYD1 Q9VYD1 Set2 PTHR22884:SF413 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE SET2 transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 DROME|FlyBase=FBgn0028949|UniProtKB=Q9V3M3 Q9V3M3 BG:BACR44L22.2 PTHR10127:SF914 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0053257|UniProtKB=Q7KUP8 Q7KUP8 CG13037 PTHR37161:SF3 HDC10475 HDC10475 DROME|FlyBase=FBgn0033742|UniProtKB=A1Z910 A1Z910 Nepl10 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0031265|UniProtKB=Q9VPR3 Q9VPR3 Dmel\CG2794 PTHR42909:SF1 ZGC:136858 CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0016691|UniProtKB=Q24439 Q24439 ATPsynO PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT OSCP, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 DROME|FlyBase=FBgn0005672|UniProtKB=Q01083 Q01083 spi PTHR12332:SF1 KEREN-RELATED KEREN-RELATED cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 DROME|FlyBase=FBgn0021874|UniProtKB=Q9VPR4 Q9VPR4 Nle PTHR19848:SF10 WD40 REPEAT PROTEIN NOTCHLESS PROTEIN HOMOLOG 1 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of Notch signaling pathway#GO:0008593;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0260753|UniProtKB=Q9W4Y2 Q9W4Y2 Pdfr PTHR45620:SF17 PDF RECEPTOR-LIKE PROTEIN-RELATED PDF RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0083945|UniProtKB=Q0IGY6 Q0IGY6 CG12441 PTHR20992:SF12 AT15442P-RELATED IP07646P DROME|FlyBase=FBgn0037443|UniProtKB=E1JJ71 E1JJ71 Dmtn PTHR17613:SF14 CEREBRAL PROTEIN-11-RELATED DEMENTIN, ISOFORM H endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039740|UniProtKB=Q9VAB8 Q9VAB8 ZIPIC PTHR24406:SF24 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN ZIPIC zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0004649|UniProtKB=P98163 P98163 yl PTHR24270:SF8 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED VITELLOGENIN RECEPTOR YL plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transfer/carrier protein#PC00219;apolipoprotein#PC00052 DROME|FlyBase=FBgn0039857|UniProtKB=Q9V9W3 Q9V9W3 RpL6 PTHR10715:SF0 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 DROME|FlyBase=FBgn0015527|UniProtKB=O61345 O61345 peng PTHR13389:SF0 PUMILIO HOMOLOG 3 PUMILIO HOMOLOG 3 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0030151|UniProtKB=Q8SWU7 Q8SWU7 CG1354 PTHR23305:SF11 OBG GTPASE FAMILY OBG-LIKE ATPASE 1 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 DROME|FlyBase=FBgn0035735|UniProtKB=Q9VS12 Q9VS12 Cpr65Ea PTHR10380:SF238 CUTICLE PROTEIN CUTICULAR PROTEIN 65EA-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0039360|UniProtKB=Q8MZC4 Q8MZC4 CLS PTHR14269:SF60 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CARDIOLIPIN SYNTHASE (CMP-FORMING) catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039326|UniProtKB=Q961Q8 Q961Q8 Dmel\CG10562 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0030932|UniProtKB=Q9VWT3 Q9VWT3 Ggt-1 PTHR11686:SF9 GAMMA GLUTAMYL TRANSPEPTIDASE GAMMA-GLUTAMYL TRANSPEPTIDASE, ISOFORM A catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0034918|UniProtKB=P82804 P82804 Pym PTHR22959:SF0 PYM PROTEIN PARTNER OF Y14 AND MAGO RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;protein-containing complex disassembly#GO:0032984;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0002571|UniProtKB=P07192 P07192 Mal-A3 PTHR10357:SF235 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A3-RELATED carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;cellular process#GO:0009987;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;amylase#PC00048 DROME|FlyBase=FBgn0052255|UniProtKB=P83297 P83297 Gr64f PTHR21421:SF29 GUSTATORY RECEPTOR GUSTATORY RECEPTOR 5A FOR TREHALOSE-RELATED nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0040696|UniProtKB=Q9VZH1 Q9VZH1 CG18675 PTHR13238:SF0 PROTEIN C21ORF59 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298 DROME|FlyBase=FBgn0035960|UniProtKB=Q9VST8 Q9VST8 Dmel\CG4942 PTHR12428:SF70 OXA1 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 protein localization to organelle#GO:0033365;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;respiratory chain complex IV assembly#GO:0008535;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;membrane organization#GO:0061024;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0025742|UniProtKB=Q9VMI9 Q9VMI9 mtm PTHR10807:SF133 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 DROME|FlyBase=FBgn0038090|UniProtKB=Q9VG21 Q9VG21 Dmel\CG10909 PTHR10335:SF28 RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN RRNA 2'-O-METHYLTRANSFERASE FIBRILLARIN transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;histone methyltransferase activity#GO:0042054;binding#GO:0005488;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;nucleic acid binding#GO:0003676;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;RNA binding#GO:0003723 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;rRNA methylation#GO:0031167;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904 RNA processing factor#PC00147 DROME|FlyBase=FBgn0037424|UniProtKB=Q9VNN7 Q9VNN7 Osi15 PTHR21879:SF5 FI03362P-RELATED-RELATED OSIRIS 15 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033749|UniProtKB=A1Z916 A1Z916 achi PTHR11850:SF59 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0052213|UniProtKB=Q8IQU6 Q8IQU6 Dmel\CG32213 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0033454|UniProtKB=Q7JQT9 Q7JQT9 Dmel\CG1671 PTHR19854:SF15 TRANSDUCIN BETA-LIKE 3 TRANSDUCIN BETA-LIKE PROTEIN 3 RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511;nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;90S preribosome#GO:0030686;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0028901|UniProtKB=Q4LDP4 Q4LDP4 t-Grip91 PTHR19302:SF33 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 5 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0027496|UniProtKB=Q9Y0Y5 Q9Y0Y5 epsilonCOP PTHR10805:SF0 COATOMER SUBUNIT EPSILON COATOMER SUBUNIT EPSILON Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle membrane#GO:0012506;membrane#GO:0016020 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0051141|UniProtKB=Q8IMY2 Q8IMY2 Dmel\CG31141 PTHR11157:SF116 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0036333|UniProtKB=Q9VU34 Q9VU34 MICAL-like PTHR23167:SF96 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED ALPHA ACTININ 3-RELATED actin filament-based process#GO:0030029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0000038|UniProtKB=P04755 P04755 nAChRbeta1 PTHR18945:SF784 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-LIKE 1 neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 DROME|FlyBase=FBgn0034527|UniProtKB=Q7JYQ4 Q7JYQ4 Dmel\CG9945 PTHR19847:SF7 DDB1- AND CUL4-ASSOCIATED FACTOR 11 DDB1- AND CUL4-ASSOCIATED FACTOR 11 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0262739|UniProtKB=Q32KD4 Q32KD4 AGO1 PTHR22891:SF198 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-1 catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 DROME|FlyBase=FBgn0053772|UniProtKB=Q4ABH4 Q4ABH4 BP1031 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0030706|UniProtKB=Q9VXM0 Q9VXM0 Lrp4 PTHR24270:SF67 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 4 receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0032705|UniProtKB=Q9VJ57 Q9VJ57 Grip71 PTHR44414:SF1 PROTEIN NEDD1 PROTEIN NEDD1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle#GO:0000278;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 DROME|FlyBase=FBgn0036709|UniProtKB=Q9VVF3 Q9VVF3 Or74a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0043002|UniProtKB=Q9V444 Q9V444 Chrac-14 PTHR46172:SF1 DNA POLYMERASE EPSILON SUBUNIT 3 DNA POLYMERASE EPSILON SUBUNIT 3 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682 cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;DNA strand elongation involved in DNA replication#GO:0006271;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0037299|UniProtKB=Q9VN88 Q9VN88 Vps37B PTHR13678:SF27 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 LD45836P macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein targeting to vacuole#GO:0006623;establishment of protein localization to membrane#GO:0090150;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein transport#GO:0015031;cellular localization#GO:0051641 vesicle membrane#GO:0012506;ESCRT I complex#GO:0000813;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0260407|UniProtKB=Q8IP62 Q8IP62 mRpS23 PTHR15925:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S23 SMALL RIBOSOMAL SUBUNIT PROTEIN MS23 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0260758|UniProtKB=E1JHJ7 E1JHJ7 CG15133 PTHR13192:SF3 MY011 PROTEIN COBALAMIN TRAFFICKING PROTEIN CBLD metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0045823|UniProtKB=M9PHX2 M9PHX2 vsg PTHR11337:SF8 MUCIN/PORIMIN VISGUN, ISOFORM E intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0034128|UniProtKB=A1ZAG3 A1ZAG3 Dmel\CG4409 PTHR21163:SF1 PROTEIN G12 PROTEIN G12 DROME|FlyBase=FBgn0260987|UniProtKB=O96689 O96689 vtd PTHR12585:SF69 SCC1 / RAD21 FAMILY MEMBER FI11703P binding#GO:0005488;chromatin binding#GO:0003682 cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;sister chromatid cohesion#GO:0007062;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;double-strand break repair#GO:0006302 chromosome#GO:0005694;organelle#GO:0043226;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0259171|UniProtKB=Q9I7S6 Q9I7S6 Pde9 PTHR11347:SF209 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112 purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;regulation of cellular process#GO:0050794;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;regulation of response to stimulus#GO:0048583;cyclic nucleotide metabolic process#GO:0009187;nucleotide catabolic process#GO:0009166;negative regulation of cellular process#GO:0048523;cGMP metabolic process#GO:0046068;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;ribonucleotide metabolic process#GO:0009259;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;small molecule metabolic process#GO:0044281;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;negative regulation of signal transduction#GO:0009968 phosphodiesterase#PC00185;hydrolase#PC00121 DROME|FlyBase=FBgn0001233|UniProtKB=P02828 P02828 Hsp83 PTHR11528:SF34 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 83 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ATP-dependent activity#GO:0140657;ATP binding#GO:0005524;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of protein stability#GO:0031647;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein stabilization#GO:0050821;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Hsp90 family chaperone#PC00028;chaperone#PC00072 DROME|FlyBase=FBgn0028746|UniProtKB=O97172 O97172 CG18508 PTHR13456:SF0 UPF0729 PROTEIN C18ORF32 UPF0729 PROTEIN C18ORF32 DROME|FlyBase=FBgn0026879|UniProtKB=Q9XZS3 Q9XZS3 CG13364 PTHR28632:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 DROME|FlyBase=FBgn0050291|UniProtKB=Q95SK3 Q95SK3 CG30291 PTHR14894:SF0 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cell cycle#GO:0051726;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;signal transduction#GO:0007165 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0260755|UniProtKB=Q9W0M6 Q9W0M6 CG13886 PTHR13379:SF0 UNCHARACTERIZED DUF1308 UPF0415 PROTEIN C7ORF25 DROME|FlyBase=FBgn0037037|UniProtKB=Q9VP94 Q9VP94 Dmel\CG10588 PTHR43690:SF40 NARDILYSIN NARDILYSIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0051313|UniProtKB=Q8SZN1 Q8SZN1 Dmel\CG31313 PTHR12319:SF2 CYSTATIN-RELATED CYSTATIN-LIKE PROTEIN-RELATED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0038069|UniProtKB=Q9VG47 Q9VG47 Dmel\CG11608 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0037120|UniProtKB=Q9VNZ4 Q9VNZ4 Saft PTHR24393:SF85 ZINC FINGER PROTEIN FI01120P DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0036735|UniProtKB=Q9VVI2 Q9VVI2 Edc3 PTHR13612:SF0 ENHANCER OF MRNA-DECAPPING PROTEIN 3 ENHANCER OF MRNA-DECAPPING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;molecular condensate scaffold activity#GO:0140693 nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;P-body assembly#GO:0033962;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;RNA decapping#GO:0110154;organelle organization#GO:0006996;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0050159|UniProtKB=Q7K332 Q7K332 CG3364 PTHR28434:SF1 PROTEIN C3ORF33 MITOCHONDRIAL INNER MEMBRANE SUBDOMAIN ORGANIZER 1 DROME|FlyBase=FBgn0015019|UniProtKB=P48605 P48605 CCT3 PTHR11353:SF24 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT GAMMA protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 DROME|FlyBase=FBgn0024277|UniProtKB=Q7KVD1 Q7KVD1 trio PTHR22826:SF106 RHO GUANINE EXCHANGE FACTOR-RELATED TRIO, ISOFORM A guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;extrinsic component of membrane#GO:0019898;cellular anatomical structure#GO:0110165;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0284256|UniProtKB=Q9VJ86 Q9VJ86 bsf PTHR46669:SF1 LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0261679|UniProtKB=Q8INE2 Q8INE2 CG31392 PTHR23226:SF449 ZINC FINGER AND SCAN DOMAIN-CONTAINING FI21258P1 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0046114|UniProtKB=Q9VCW6 Q9VCW6 Gclm PTHR13295:SF4 GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899 modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987;peptide metabolic process#GO:0006518;biosynthetic process#GO:0009058 catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;ligase#PC00142 DROME|FlyBase=FBgn0028509|UniProtKB=Q9NGC3 Q9NGC3 CenG1A PTHR45819:SF5 CENTAURIN-GAMMA-1A CENTAURIN-GAMMA-1A GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;enzyme activator activity#GO:0008047;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function activator activity#GO:0140677;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0033159|UniProtKB=Q0E9H9 Q0E9H9 Dscam1 PTHR10075:SF53 BASIGIN RELATED CELL ADHESION MOLECULE DSCAM1 system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0037413|UniProtKB=Q9VNM6 Q9VNM6 Osi5 PTHR21879:SF23 FI03362P-RELATED-RELATED IP06949P cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0033388|UniProtKB=A1Z7R6 A1Z7R6 SLC46 PTHR23507:SF39 ZGC:174356 GH23453P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0036856|UniProtKB=Q8MSW4 Q8MSW4 Mettl5 PTHR23290:SF0 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 RRNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL5 catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167 DROME|FlyBase=FBgn0040725|UniProtKB=Q9VPS9 Q9VPS9 Dmel\CG13946 PTHR22552:SF25 GEO11429P1 GEO11429P1-RELATED DROME|FlyBase=FBgn0032430|UniProtKB=Q9VK89 Q9VK89 Trm1 PTHR10631:SF14 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030217|UniProtKB=Q9W2T3 Q9W2T3 Dmel\CG2124 PTHR21228:SF73 FAST LEU-RICH DOMAIN-CONTAINING RAP DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA stability#GO:0043487;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774 mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membraneless organelle#GO:0043228 RNA processing factor#PC00147 DROME|FlyBase=FBgn0039970|UniProtKB=A1Z6G4 A1Z6G4 Dmel\CG17508 PTHR21377:SF0 PROTEIN FAM210B, MITOCHONDRIAL PROTEIN FAM210B, MITOCHONDRIAL organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0037764|UniProtKB=Q4V3H4 Q4V3H4 Dmel\CG9459 PTHR11157:SF116 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0039796|UniProtKB=Q9VA47 Q9VA47 Dmel\CG12069 PTHR24353:SF152 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE UT01108P-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437 DROME|FlyBase=FBgn0001227|UniProtKB=P05812 P05812 Hsp67Ba PTHR45640:SF40 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN 22-RELATED metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0037435|UniProtKB=Q8SX24 Q8SX24 Dmel\CG18048 PTHR12998:SF0 TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396 DROME|FlyBase=FBgn0032147|UniProtKB=Q9VL83 Q9VL83 IP3K1 PTHR12400:SF110 INOSITOL POLYPHOSPHATE KINASE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137 DROME|FlyBase=FBgn0262587|UniProtKB=A0A0B4K7P3 A0A0B4K7P3 Dmel\CG43124 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0030946|UniProtKB=Q9VWR8 Q9VWR8 CG6659 PTHR31488:SF1 DPY-19-LIKE 1, LIKE (H. SAPIENS) DPY-19 LIKE C-MANNOSYLTRANSFERASE 1 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 DROME|FlyBase=FBgn0031457|UniProtKB=Q9VQG1 Q9VQG1 Snx21 PTHR20939:SF11 SORTING NEXIN 20, 21 LD12265P phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033349|UniProtKB=A1Z7K6 A1Z7K6 SMAP PTHR45705:SF1 FI20236P1 FI20236P1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0051323|UniProtKB=Q8SYP1 Q8SYP1 CG14558 PTHR38332:SF1 PROTEIN CBG11604 RE49668P DROME|FlyBase=FBgn0259985|UniProtKB=A0A0B4LF50 A0A0B4LF50 Mppe PTHR13315:SF4 METALLO PHOSPHOESTERASE RELATED METALLOPHOSPHOESTERASE, ISOFORM E glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 DROME|FlyBase=FBgn0037051|UniProtKB=Q9VP77 Q9VP77 Dmel\CG10565 PTHR43999:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072;Hsp70 protein binding#GO:0030544;binding#GO:0005488;protein binding#GO:0005515;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 DROME|FlyBase=FBgn0263006|UniProtKB=P22700 P22700 SERCA PTHR42861:SF102 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM TYPE monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068 DROME|FlyBase=FBgn0033924|UniProtKB=Q5BIA9 Q5BIA9 Dmel\CG8613 PTHR42899:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 DROME|FlyBase=FBgn0031977|UniProtKB=Q9VLU0 Q9VLU0 baf PTHR47507:SF6 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0262593|UniProtKB=P17970 P17970 Shab PTHR11537:SF289 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;action potential#GO:0001508;metal ion transport#GO:0030001;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 ion channel#PC00133;voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0026597|UniProtKB=Q9V407 Q9V407 Axn PTHR46102:SF2 AXIN AXIN protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389 negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;cell development#GO:0048468;regulation of Wnt signaling pathway#GO:0030111;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;negative regulation of biological process#GO:0048519;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of signal transduction#GO:0009968;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;anatomical structure development#GO:0048856;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of catabolic process#GO:0009894;cellular developmental process#GO:0048869;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 DROME|FlyBase=FBgn0030555|UniProtKB=Q9VY46 Q9VY46 Fbxl4 PTHR13318:SF152 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 4 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 DROME|FlyBase=FBgn0034646|UniProtKB=Q9W2E7 Q9W2E7 Rae1 PTHR10971:SF11 MRNA EXPORT FACTOR AND BUB3 MRNA EXPORT FACTOR RAE1 ubiquitin binding#GO:0043130;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;protein binding#GO:0005515 cellular component organization#GO:0016043;nucleobase-containing compound transport#GO:0015931;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle organization#GO:0006996;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;chromosome organization#GO:0051276 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035005|UniProtKB=Q9W172 Q9W172 anon-WO0140519.111 PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol metabolic process#GO:0006066;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 oxidoreductase#PC00176;dehydrogenase#PC00092 Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001 DROME|FlyBase=FBgn0265089|UniProtKB=Q9VSG1 Q9VSG1 eIF4E3 PTHR11960:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 DROME|FlyBase=FBgn0020440|UniProtKB=B7YZL9 B7YZL9 Fak PTHR46221:SF9 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FOCAL ADHESION KINASE 1-RELATED VEGF signaling pathway#P00056>FAK#P01420;Integrin signalling pathway#P00034>FAK#P00932;Angiogenesis#P00005>FAK#P00209 DROME|FlyBase=FBgn0263933|UniProtKB=Q95RJ9 Q95RJ9 ebi PTHR22846:SF2 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 Wnt signaling pathway#P00057>Ebi#P01453 DROME|FlyBase=FBgn0034736|UniProtKB=Q9W243 Q9W243 gas PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0028527|UniProtKB=Q7KTB0 Q7KTB0 DS01368.1 PTHR31193:SF1 TRANSMEMBRANE PROTEIN C9ORF91 TRANSMEMBRANE PROTEIN 268 DROME|FlyBase=FBgn0010423|UniProtKB=P47948 P47948 TpnC47D PTHR23050:SF244 CALCIUM BINDING PROTEIN TROPONIN C, ISOFORM 2-RELATED calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0035328|UniProtKB=Q9W028 Q9W028 yellow-g2 PTHR10009:SF8 PROTEIN YELLOW-RELATED IP19120P cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0032615|UniProtKB=Q9VJG8 Q9VJG8 Dmel\CG6012 PTHR43899:SF9 RH59310P MIP25013P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0028534|UniProtKB=Q9V3U5 Q9V3U5 LP05416 PTHR20993:SF0 GH07914P GH07914P DROME|FlyBase=FBgn0033097|UniProtKB=A1Z6P0 A1Z6P0 Zip42C.2 PTHR11040:SF203 ZINC/IRON TRANSPORTER FI18611P1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0031359|UniProtKB=Q9VQ37 Q9VQ37 Rim2 PTHR45829:SF4 MITOCHONDRIAL CARRIER PROTEIN RIM2 MITOCHONDRIAL CARRIER PROTEIN RIM2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0052647|UniProtKB=Q9VYJ3 Q9VYJ3 CG15723 PTHR15256:SF6 INTEGRAL MEMBRANE PROTEIN DGCR2/IDD INTEGRAL MEMBRANE PROTEIN DGCR2_IDD membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0086679|UniProtKB=Q9VHN9 Q9VHN9 p PTHR23287:SF18 RUBY-EYE2-LIKE PROTEIN BLOC-2 COMPLEX MEMBER HPS5 pigmentation#GO:0043473;developmental pigmentation#GO:0048066 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0286204|UniProtKB=Q9VHJ6 Q9VHJ6 ich PTHR24393:SF138 ZINC FINGER PROTEIN IP01201P-RELATED binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0030718|UniProtKB=Q9VXK7 Q9VXK7 ND-20 PTHR11995:SF14 NADH DEHYDROGENASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;NADH dehydrogenase activity#GO:0003954 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;establishment of localization#GO:0051234;cellular respiration#GO:0045333;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;aerobic respiration#GO:0009060;metabolic process#GO:0008152;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091 respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0286511|UniProtKB=B7YZT5 B7YZT5 Pld PTHR18896:SF204 PHOSPHOLIPASE D PHOSPHOLIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;organophosphate catabolic process#GO:0046434;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 lipase#PC00143;phospholipase#PC00186 Angiogenesis#P00005>PLD#P00204 DROME|FlyBase=FBgn0015268|UniProtKB=Q9W1G7 Q9W1G7 Nap1 PTHR11875:SF7 TESTIS-SPECIFIC Y-ENCODED PROTEIN AT14585P-RELATED binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515 protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0085234|UniProtKB=Q9W287 Q9W287 CG13504 PTHR15363:SF4 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 CUTICLE PROTEIN 16.5-RELATED transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0261434|UniProtKB=Q9VN10 Q9VN10 hkb PTHR23235:SF139 KRUEPPEL-LIKE TRANSCRIPTION FACTOR HUCKEBEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0045477|UniProtKB=P83295 P83295 Gr64c PTHR21421:SF35 GUSTATORY RECEPTOR GUSTATORY RECEPTOR FOR SUGAR TASTE 64B-RELATED molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;sensory perception#GO:0007600 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0030003|UniProtKB=Q9W3J9 Q9W3J9 Dmel\CG2116 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0046253|UniProtKB=Q9W1S1 Q9W1S1 BEST:LD34564 PTHR11533:SF253 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0015602|UniProtKB=Q7JN06 Q7JN06 BEAF-32 PTHR34396:SF25 OS03G0264950 PROTEIN-RELATED BOUNDARY ELEMENT ASSOCIATED FACTOR regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0035736|UniProtKB=Q8MZ06 Q8MZ06 Cpr65Eb PTHR10380:SF230 CUTICLE PROTEIN CUTICULAR PROTEIN 47EE-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0004910|UniProtKB=P48593 P48593 Eip63F-1 PTHR23050:SF558 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 6 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0032987|UniProtKB=Q9V9M7 Q9V9M7 RpL21 PTHR20981:SF6 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 DROME|FlyBase=FBgn0036536|UniProtKB=Q9VUU6 Q9VUU6 Dmel\CG12713 PTHR31661:SF1 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 DROME|FlyBase=FBgn0036509|UniProtKB=Q9VUQ7 Q9VUQ7 Dmel\CG7739 PTHR13412:SF0 T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG T-CELL IMMUNOMODULATORY PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0041234|UniProtKB=Q9W1N5 Q9W1N5 Gr59f PTHR21143:SF121 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 59F-RELATED cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039420|UniProtKB=Q9VBG1 Q9VBG1 Dmel\CG6154 PTHR10443:SF46 MICROSOMAL DIPEPTIDASE DIPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0035232|UniProtKB=Q9W0D8 Q9W0D8 Dmel\CG12099 PTHR12983:SF9 RING FINGER 10 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RNF10 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036396|UniProtKB=Q9VUB3 Q9VUB3 Dmel\CG17359 PTHR24390:SF269 ZINC FINGER PROTEIN RE58063P sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0034025|UniProtKB=Q6WV20 Q6WV20 Pgant1 PTHR11675:SF43 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0031684|UniProtKB=Q9VMU0 Q9VMU0 ND-13A PTHR13156:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 mitochondrial inner membrane#GO:0005743;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 DROME|FlyBase=FBgn0036329|UniProtKB=Q9VU30 Q9VU30 Dmel\CG11262 PTHR43568:SF1 P PROTEIN CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0039203|UniProtKB=Q9VC67 Q9VC67 Jhbp12 PTHR11008:SF42 PROTEIN TAKEOUT-LIKE PROTEIN CIRCADIAN CLOCK-CONTROLLED PROTEIN DAYWAKE-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0038302|UniProtKB=Q8MRT7 Q8MRT7 Sat PTHR10545:SF29 DIAMINE N-ACETYLTRANSFERASE GH14572P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 transferase#PC00220;acetyltransferase#PC00038 DROME|FlyBase=FBgn0031644|UniProtKB=Q9VR43 Q9VR43 Dmel\CG15625 PTHR12573:SF4 AT09986P-RELATED AT09986P-RELATED DROME|FlyBase=FBgn0031764|UniProtKB=Q9VMJ1 Q9VMJ1 Rrp7 PTHR13191:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0037398|UniProtKB=Q9VNK8 Q9VNK8 Dmel\CG15580 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0051423|UniProtKB=Q8IN08 Q8IN08 Ir94c PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0038106|UniProtKB=Q9VG07 Q9VG07 Dmel\CG7488 PTHR42698:SF1 GTPASE ERA GTPASE ERA, MITOCHONDRIAL ribosomal small subunit biogenesis#GO:0042274;protein-containing complex organization#GO:0043933;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034498|UniProtKB=Q5BI42 Q5BI42 CG16868 PTHR10166:SF68 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VWFA AND CACHE DOMAIN-CONTAINING PROTEIN 1 voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;transporter#PC00227 DROME|FlyBase=FBgn0288856|UniProtKB=Q7K4V4 Q7K4V4 peo PTHR24067:SF294 UBIQUITIN-CONJUGATING ENZYME E2 PROTEIN CROSSBRONX-LIKE-RELATED aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 response to stress#GO:0006950;cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0053966|UniProtKB=Q2MGL8 Q2MGL8 Dmel\CG33966 PTHR10174:SF216 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN-RELATED phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0015271|UniProtKB=Q24169 Q24169 Orc5 PTHR12705:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688 nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;nuclear origin of replication recognition complex#GO:0005664;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 replication origin binding protein#PC00199 DROME|FlyBase=FBgn0259726|UniProtKB=B7YZN4 B7YZN4 Dmel\CG42380 PTHR34561:SF1 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8 mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0029685|UniProtKB=Q9W4P0 Q9W4P0 Dmel\CG2938 PTHR13533:SF1 N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE LD22456P acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0028532|UniProtKB=Q9V3H6 Q9V3H6 BG:DS00941.15 PTHR20993:SF0 GH07914P GH07914P DROME|FlyBase=FBgn0023175|UniProtKB=Q9V5C6 Q9V5C6 Prosalpha7 PTHR11599:SF10 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-3 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0012058|UniProtKB=Q9VS37 Q9VS37 Cdc27 PTHR12558:SF13 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 27 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;protein modification by small protein conjugation or removal#GO:0070647;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of chromosome segregation#GO:0051983;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cell cycle#GO:0007049;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;post-translational protein modification#GO:0043687;biological regulation#GO:0065007 nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;cytoplasm#GO:0005737;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0053927|UniProtKB=Q4ABH2 Q4ABH2 Dmel\CG33927 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0034175|UniProtKB=A1ZAM7 A1ZAM7 ste24b PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 metalloprotease#PC00153 DROME|FlyBase=FBgn0039304|UniProtKB=Q9VBU5 Q9VBU5 Kdsr PTHR43550:SF3 3-KETODIHYDROSPHINGOSINE REDUCTASE 3-KETODIHYDROSPHINGOSINE REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0053792|UniProtKB=A1Z931 A1Z931 Dmel\CG33792 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0262509|UniProtKB=M9NE05 M9NE05 nrm PTHR23278:SF32 SIDESTEP PROTEIN NEUROMUSCULIN, ISOFORM E immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0002872|UniProtKB=Q95RC8 Q95RC8 mu2 PTHR23196:SF42 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN PAX-INTERACTING PROTEIN 1 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stress#GO:0006950 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0011659|UniProtKB=A1Z7C1 A1Z7C1 Mlh1 PTHR10073:SF59 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MLH1, ISOFORM A catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;mismatch repair#GO:0006298;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0015278|UniProtKB=Q7K3H0 Q7K3H0 Pi3K68D PTHR10048:SF14 PHOSPHATIDYLINOSITOL KINASE LD28067P phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 kinase#PC00137 VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;p53 pathway feedback loops 2#P04398>PI3K#P04661;FGF signaling pathway#P00021>PI3K#P00640;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;Apoptosis signaling pathway#P00006>PI3K#P00310;PDGF signaling pathway#P00047>PI3K#P01168;EGF receptor signaling pathway#P00018>PI3K#P00557;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236 DROME|FlyBase=FBgn0034354|UniProtKB=Q7JVZ8 Q7JVZ8 GstE11 PTHR43969:SF3 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE E11, ISOFORM A-RELATED glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 transferase#PC00220 DROME|FlyBase=FBgn0015778|UniProtKB=Q9VFT4 Q9VFT4 rin PTHR10693:SF88 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN AT27578P RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0085447|UniProtKB=P91621 P91621 sif PTHR46001:SF3 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG PROTEIN STILL LIFE, ISOFORM SIF TYPE 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0000709|UniProtKB=Q24020 Q24020 fliI PTHR11977:SF142 VILLIN PROTEIN FLIGHTLESS-1 HOMOLOG protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092 cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;regulation of protein-containing complex disassembly#GO:0043244;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;myofibril assembly#GO:0030239;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;supramolecular fiber organization#GO:0097435;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament capping#GO:0051693;organelle assembly#GO:0070925;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;regulation of anatomical structure size#GO:0090066;negative regulation of actin filament polymerization#GO:0030837;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;striated muscle cell development#GO:0055002;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;actin polymerization or depolymerization#GO:0008154;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex assembly#GO:0031333;anatomical structure development#GO:0048856;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927 nucleus#GO:0005634;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0004854|UniProtKB=Q24256 Q24256 B-H2 PTHR24330:SF10 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN B-H1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0035169|UniProtKB=Q9W0M0 Q9W0M0 Dci PTHR43684:SF18 FAMILY NOT NAMED DODECENOYL-COA DELTA-ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0034539|UniProtKB=A1ZBX7 A1ZBX7 Dmel\CG11159 PTHR11407:SF75 LYSOZYME C LYSOZYME hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;lysozyme activity#GO:0003796;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycosidase#PC00110 DROME|FlyBase=FBgn0037880|UniProtKB=Q9VGR2 Q9VGR2 CG17726 PTHR12049:SF7 PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0287204|UniProtKB=Q9VKH0 Q9VKH0 Cog8 PTHR21311:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8 retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;COG complex#GO:0017119;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0038168|UniProtKB=Q9VFS6 Q9VFS6 omd PTHR31697:SF2 INTEGRATOR COMPLEX SUBUNIT 5 INTEGRATOR COMPLEX SUBUNIT 5 snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039 DROME|FlyBase=FBgn0261549|UniProtKB=Q09103 Q09103 rdgA PTHR11255:SF127 DIACYLGLYCEROL KINASE EYE-SPECIFIC DIACYLGLYCEROL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;kinase#PC00137 DROME|FlyBase=FBgn0030514|UniProtKB=Q9VY98 Q9VY98 Mgrn1 PTHR22996:SF30 MAHOGUNIN RE60872P-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0287225|UniProtKB=Q9VEX6 Q9VEX6 bor PTHR23075:SF0 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3A cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0032848|UniProtKB=Q9VIP0 Q9VIP0 nesd PTHR14695:SF9 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED PROTEIN NESSUN DORMA meiotic cell cycle#GO:0051321;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;cellular process#GO:0009987;male gamete generation#GO:0048232;male meiotic nuclear division#GO:0007140;cytokinesis#GO:0000910;nuclear division#GO:0000280;sexual reproduction#GO:0019953;cytoskeleton-dependent cytokinesis#GO:0061640;organelle fission#GO:0048285;multicellular organismal reproductive process#GO:0048609;cell cycle#GO:0007049;cellular component organization#GO:0016043;developmental process involved in reproduction#GO:0003006;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;cell division#GO:0051301;gamete generation#GO:0007276;reproductive process#GO:0022414 DROME|FlyBase=FBgn0039260|UniProtKB=Q9VBZ6 Q9VBZ6 Smg6 PTHR15696:SF0 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 TELOMERASE-BINDING PROTEIN EST1A binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;RNA binding#GO:0003723;DNA binding#GO:0003677 macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031347|UniProtKB=Q9VQ22 Q9VQ22 nis PTHR46766:SF1 GLUTAMINE-RICH PROTEIN 2 GLUTAMINE RICH 2 DROME|FlyBase=FBgn0027873|UniProtKB=Q9V3D6 Q9V3D6 Cpsf100 PTHR45922:SF2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0053627|UniProtKB=A1Z8Z6 A1Z8Z6 Dmel\CG33627 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0028569|UniProtKB=Q9VJ18 Q9VJ18 robl37BC PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0028429|UniProtKB=A8JNP7 A8JNP7 I-2 PTHR12398:SF20 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2 phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 phosphatase inhibitor#PC00183 DROME|FlyBase=FBgn0031775|UniProtKB=Q9VMH9 Q9VMH9 Dmel\CG9150 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0037720|UniProtKB=Q9VHA6 Q9VHA6 Dmel\CG8312 PTHR11232:SF2 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER FI05246P signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0001263|UniProtKB=Q24008 Q24008 inaD PTHR19964:SF93 MULTIPLE PDZ DOMAIN PROTEIN INACTIVATION-NO-AFTER-POTENTIAL D PROTEIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0286778|UniProtKB=A0A4P7VA97 A0A4P7VA97 NEST:bs36c04 PTHR12974:SF36 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 POLYNUCLEOTIDE ADENYLYLTRANSFERASE nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311 DROME|FlyBase=FBgn0040056|UniProtKB=A4V2C3 A4V2C3 Dmel\CG17698 PTHR24343:SF594 SERINE/THREONINE KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0052371|UniProtKB=Q8IQA0 Q8IQA0 Dmel\CG32371 PTHR10623:SF6 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER EB1, ISOFORM F-RELATED protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;protein localization to microtubule cytoskeleton#GO:0072698;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;intracellular protein localization#GO:0008104;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein localization to cytoskeleton#GO:0044380;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886 microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0003310|UniProtKB=P42519 P42519 S PTHR34009:SF2 PROTEIN STAR PROTEIN STAR endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;late endosome membrane#GO:0031902;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0052319|UniProtKB=Q8IRH2 Q8IRH2 Naa30B PTHR45896:SF1 N-ALPHA-ACETYLTRANSFERASE 30 N-ALPHA-ACETYLTRANSFERASE 30 N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0052069|UniProtKB=Q9VTE1 Q9VTE1 Dmel\CG32069 PTHR15858:SF7 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 positive regulation of cellular component organization#GO:0051130;positive regulation of secretion#GO:0051047;regulation of secretion by cell#GO:1903530;regulation of establishment of protein localization#GO:0070201;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;regulation of protein localization#GO:0032880;cellular localization#GO:0051641;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of protein secretion#GO:0050714;establishment of localization#GO:0051234;cellular process#GO:0009987;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 DROME|FlyBase=FBgn0032436|UniProtKB=Q9VK81 Q9VK81 Dmel\CG5418 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 DROME|FlyBase=FBgn0262515|UniProtKB=Q7JR49 Q7JR49 VhaAC45 PTHR12471:SF7 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;ATPase complex#GO:1904949;catalytic complex#GO:1902494 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0014857|UniProtKB=C0HL66 C0HL66 His3.3A PTHR11426:SF287 HISTONE H3 HISTONE H3.3A-RELATED nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 DROME|FlyBase=FBgn0032172|UniProtKB=M9PD30 M9PD30 Dmel\CG5850 PTHR23423:SF10 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184C transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0039588|UniProtKB=Q9VAV2 Q9VAV2 mIF2 PTHR43381:SF20 TRANSLATION INITIATION FACTOR IF-2-RELATED TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translation initiation factor#PC00224 DROME|FlyBase=FBgn0000115|UniProtKB=P25160 P25160 Arl1 PTHR11711:SF41 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1 carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 DROME|FlyBase=FBgn0259199|UniProtKB=B7Z0I7 B7Z0I7 Snup PTHR13403:SF6 SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1 SNURPORTIN-1 transporter#PC00227 DROME|FlyBase=FBgn0033236|UniProtKB=Q7K0S1 Q7K0S1 Dmel\CG14764 PTHR31389:SF4 LD39211P LD39211P DROME|FlyBase=FBgn0030616|UniProtKB=Q9VXX8 Q9VXX8 RpL37-1 PTHR10768:SF0 60S RIBOSOMAL PROTEIN L37 RIBOSOMAL PROTEIN L37 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 DROME|FlyBase=FBgn0035087|UniProtKB=Q9W0X5 Q9W0X5 Dmel\CG2765 PTHR14315:SF17 SPOT14 FAMILY MEMBER MIP21584P regulation of lipid metabolic process#GO:0019216;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0002534|UniProtKB=P07188 P07188 Lcp3 PTHR10380:SF230 CUTICLE PROTEIN CUTICULAR PROTEIN 47EE-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0037766|UniProtKB=A0A0B4KGN9 A0A0B4KGN9 Teh1 PTHR12335:SF4 TIPE PROTEIN TEMPERATURE-INDUCED PARALYTIC E TIPE HOMOLOG 1, ISOFORM B ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0030314|UniProtKB=Q9VYX2 Q9VYX2 Dmel\CG11696 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0032010|UniProtKB=M9PB71 M9PB71 Dmel\CG8086 PTHR21580:SF28 SHIPPO-1-RELATED SPERM-TAIL PG-RICH REPEAT FAMILY PROTEIN intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165 structural protein#PC00211 DROME|FlyBase=FBgn0039754|UniProtKB=Q9VA94 Q9VA94 Dmel\CG9747 PTHR11351:SF21 ACYL-COA DESATURASE GH07782P-RELATED iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;unsaturated fatty acid biosynthetic process#GO:0006636;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 DROME|FlyBase=FBgn0038235|UniProtKB=Q9VFJ1 Q9VFJ1 Dmel\CG8461 PTHR21738:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0040397|UniProtKB=M9PGK1 M9PGK1 EG:103E12.3 PTHR21461:SF83 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0039048|UniProtKB=Q9VCR4 Q9VCR4 Dmel\CG17111 PTHR47327:SF23 FI18240P1-RELATED FI17836P1 developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856 DROME|FlyBase=FBgn0025621|UniProtKB=Q9W5D3 Q9W5D3 Dmel\CG16989 PTHR13366:SF0 MALARIA ANTIGEN-RELATED HEAT REPEAT-CONTAINING PROTEIN 6 DROME|FlyBase=FBgn0039050|UniProtKB=Q8T490 Q8T490 Dmel\CG17110 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 DROME|FlyBase=FBgn0052633|UniProtKB=Q960J9 Q960J9 CG1733 PTHR31649:SF10 AGAP009604-PA IP19903P-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0026323|UniProtKB=Q9V3Q6 Q9V3Q6 Tak1 PTHR46716:SF1 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;JNK cascade#GO:0007254;positive regulation of response to stimulus#GO:0048584;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;immune response#GO:0006955;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;TGF-beta signaling pathway#P00052>TAK#P01285;Interleukin signaling pathway#P00036>MEK#P00984;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Gonadotropin-releasing hormone receptor pathway#P06664>TAK1#P06799;p38 MAPK pathway#P05918>TAK1#P06037;Toll receptor signaling pathway#P00054>TAK1#P01370 DROME|FlyBase=FBgn0026059|UniProtKB=Q8INC3 Q8INC3 Mhcl PTHR45615:SF36 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN-LIKE, ISOFORM B-RELATED binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0037315|UniProtKB=Q9VNA6 Q9VNA6 Cerk PTHR12358:SF111 SPHINGOSINE KINASE CERAMIDE KINASE, ISOFORM A lipid kinase activity#GO:0001727;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0031260|UniProtKB=Q9VPQ7 Q9VPQ7 Spp PTHR12174:SF23 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 membrane protein proteolysis#GO:0033619;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;side of membrane#GO:0098552;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554 protein modifying enzyme#PC00260;aspartic protease#PC00053 DROME|FlyBase=FBgn0004832|UniProtKB=P28518 P28518 Xpac PTHR10142:SF0 DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684 interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular response to abiotic stimulus#GO:0071214;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;response to UV#GO:0009411;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to radiation#GO:0071478;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;base-excision repair#GO:0006284;cellular response to stress#GO:0033554 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0037848|UniProtKB=A0A0B4KFQ5 A0A0B4KFQ5 Tsp86D PTHR19282:SF489 TETRASPANIN TETRASPANIN-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0004108|UniProtKB=P23654 P23654 Nrt PTHR11559:SF417 CARBOXYLESTERASE NEUROTACTIN esterase#PC00097 DROME|FlyBase=FBgn0030505|UniProtKB=A8JUV3 A8JUV3 NFAT PTHR12533:SF7 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 DROME|FlyBase=FBgn0289743|UniProtKB=P33270 P33270 Cyp6a2 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0043471|UniProtKB=A1Z8J7 A1Z8J7 kappaTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0015400|UniProtKB=Q9VKG1 Q9VKG1 kek2 PTHR24366:SF151 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS KEKKON 2 immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0051390|UniProtKB=Q9GYV9 Q9GYV9 MED7 PTHR21428:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259 DROME|FlyBase=FBgn0014863|UniProtKB=Q24400 Q24400 Mlp84B PTHR24215:SF39 RHO-GTPASE-ACTIVATING PROTEIN LRG1 MUSCLE LIM PROTEIN MLP84B structural molecule activity#GO:0005198;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;tissue development#GO:0009888;developmental process#GO:0032502;cellular developmental process#GO:0048869;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;nucleus#GO:0005634;Z disc#GO:0030018;sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;myofibril#GO:0030016;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0024432|UniProtKB=Q94524 Q94524 Dlc90F PTHR21255:SF4 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0034433|UniProtKB=Q8SYD9 Q8SYD9 EndoB PTHR14167:SF76 SH3 DOMAIN-CONTAINING ENDOPHILIN B, ISOFORM A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030787|UniProtKB=Q9VXB4 Q9VXB4 Dmel\CG9609 PTHR24409:SF413 ZINC FINGER PROTEIN 142 DATILOGRAFO, ISOFORM A-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0032420|UniProtKB=Q9VKA1 Q9VKA1 Dmel\CG6583 PTHR33562:SF27 ATILLA, ISOFORM B-RELATED-RELATED FI02817P-RELATED DROME|FlyBase=FBgn0027375|UniProtKB=Q9V433 Q9V433 RecQ5 PTHR13710:SF152 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q5 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DNA helicase#PC00011;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0053121|UniProtKB=Q9VLV3 Q9VLV3 Spn28Db PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0010215|UniProtKB=P35220 P35220 alpha-Cat PTHR18914:SF9 ALPHA CATENIN CATENIN ALPHA binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;beta-catenin binding#GO:0008013 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell migration#GO:0016477;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;anchoring junction#GO:0070161;adherens junction#GO:0005912 non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133;Wnt signaling pathway#P00057>alpha-catenin#P01471 DROME|FlyBase=FBgn0259242|UniProtKB=A0A6H2EDG1 A0A6H2EDG1 CG12543 PTHR11003:SF325 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0035344|UniProtKB=Q9W011 Q9W011 Cyp4d20 PTHR24291:SF187 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4AE1-RELATED oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0052099|UniProtKB=Q8SXB3 Q8SXB3 eap PTHR12215:SF10 PHOSPHOPANTETHEINE TRANSFERASE L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0042132|UniProtKB=Q9I7R7 Q9I7R7 CG1809 PTHR34753:SF1 TELOMERASE RNA COMPONENT INTERACTING RNASE TELOMERASE RNA COMPONENT-INTERACTING RNASE exonuclease activity#GO:0004527;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;3'-5' exonuclease activity#GO:0008408 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0036411|UniProtKB=M9PFG6 M9PFG6 Sox21a PTHR10270:SF338 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 DROME|FlyBase=FBgn0034390|UniProtKB=Q9V8M5 Q9V8M5 Hibadh PTHR22981:SF85 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 DROME|FlyBase=FBgn0026702|UniProtKB=Q7KVW2 Q7KVW2 Pop1 PTHR22731:SF3 RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1 ribonuclease P activity#GO:0004526;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 endonuclease complex#GO:1905348;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172;intracellular membraneless organelle#GO:0043232;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;multimeric ribonuclease P complex#GO:0030681;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolar ribonuclease P complex#GO:0005655 RNA metabolism protein#PC00031;endoribonuclease#PC00094 DROME|FlyBase=FBgn0039213|UniProtKB=Q9VC57 Q9VC57 atl PTHR10751:SF29 GUANYLATE BINDING PROTEIN ATLASTIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987 heterotrimeric G-protein#PC00117;G-protein#PC00020 DROME|FlyBase=FBgn0028542|UniProtKB=Q9VJU8 Q9VJU8 NimB4 PTHR24047:SF32 FI01909P-RELATED FI01909P-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0011642|UniProtKB=Q9N675 Q9N675 Zyx PTHR24207:SF2 ZYX102 PROTEIN ZYX102 PROTEIN cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641 kinase modulator#PC00140 DROME|FlyBase=FBgn0036070|UniProtKB=Q9VT82 Q9VT82 Dmel\CG8072 PTHR10334:SF629 CYSTEINE-RICH SECRETORY PROTEIN-RELATED MIP16674P extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0034611|UniProtKB=Q8MLW5 Q8MLW5 MFS16 PTHR43184:SF31 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;phosphate transmembrane transporter activity#GO:0005315;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 transporter#PC00227 DROME|FlyBase=FBgn0035256|UniProtKB=Q9W0A6 Q9W0A6 Dmel\CG13930 PTHR12442:SF12 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 4 binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cilium movement#GO:0003341;cellular process#GO:0009987 axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0032213|UniProtKB=Q9VL01 Q9VL01 Sph35 PTHR24256:SF462 TRYPTASE-RELATED LP21446P-RELATED catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0040950|UniProtKB=Q9VMG7 Q9VMG7 Muc26B PTHR37155:SF2 MUCIN 26B MUCIN 26B DROME|FlyBase=FBgn0035558|UniProtKB=Q9VZA6 Q9VZA6 BcDNA:GM04393 PTHR11214:SF407 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0038986|UniProtKB=Q9VCY6 Q9VCY6 sit PTHR11157:SF153 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0038146|UniProtKB=Q9VFV8 Q9VFV8 Dmel\CG9799 PTHR22840:SF12 WD REPEAT-CONTAINING PROTEIN 36 WD REPEAT-CONTAINING PROTEIN 36 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0266186|UniProtKB=Q7JYX5 Q7JYX5 Vamp7 PTHR21136:SF179 SNARE PROTEINS VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484 Golgi to plasma membrane protein transport#GO:0043001;export from cell#GO:0140352;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;secretion by cell#GO:0032940;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;organelle membrane fusion#GO:0090174;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;vesicle organization#GO:0016050;microtubule-based process#GO:0007017;exocytosis#GO:0006887;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;Golgi vesicle transport#GO:0048193;membrane invagination#GO:0010324;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;vesicle fusion#GO:0006906;microtubule-based movement#GO:0007018;Golgi to plasma membrane transport#GO:0006893;catabolic process#GO:0009056;Golgi organization#GO:0007030;protein localization to plasma membrane#GO:0072659;secretion#GO:0046903;localization#GO:0051179;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;organelle localization#GO:0051640;endosome to lysosome transport#GO:0008333;membrane organization#GO:0061024;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;vesicle cytoskeletal trafficking#GO:0099518;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;vacuolar transport#GO:0007034;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;phagocytosis#GO:0006909 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150;SNARE protein#PC00034 DROME|FlyBase=FBgn0043792|UniProtKB=Q8MMC6 Q8MMC6 CG18680 PTHR11011:SF12 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 DROME|FlyBase=FBgn0026064|UniProtKB=Q9VGP9 Q9VGP9 KP78a PTHR24346:SF114 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 3-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0035786|UniProtKB=M9PEE6 M9PEE6 Tsp66A PTHR19282:SF551 TETRASPANIN TETRASPANIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051679|UniProtKB=Q9VQ95 Q9VQ95 Tengl3 PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655 cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Apoptosis signaling pathway#P00006>endoG#P00279 DROME|FlyBase=FBgn0037630|UniProtKB=Q9VHL4 Q9VHL4 Ir85a PTHR42643:SF47 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 68B-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0264694|UniProtKB=Q9VGP6 Q9VGP6 mgr PTHR12409:SF0 PREFOLDIN SUBUNIT 3 PREFOLDIN SUBUNIT 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein metabolic process#GO:0019538;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein folding#GO:0006457;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0287825|UniProtKB=Q9V7N5 Q9V7N5 Vha44 PTHR10137:SF0 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 DROME|FlyBase=FBgn0000547|UniProtKB=Q9VQW7 Q9VQW7 ed PTHR11640:SF134 NEPHRIN ECHINOID, ISOFORM A-RELATED protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0032059|UniProtKB=Q9VLJ0 Q9VLJ0 PrBP PTHR12976:SF0 RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE DELTA-SUBUNIT RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 DROME|FlyBase=FBgn0032536|UniProtKB=Q8SXX2 Q8SXX2 Ance-3 PTHR10514:SF40 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0053503|UniProtKB=Q7KR10 Q7KR10 Cyp12d1-d PTHR24305:SF238 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0032943|UniProtKB=Q9VID1 Q9VID1 Tsp39D PTHR19282:SF482 TETRASPANIN TETRASPANIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038363|UniProtKB=Q9VF36 Q9VF36 Acyp2 PTHR10029:SF3 ACYLPHOSPHATASE ACYLPHOSPHATASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 DROME|FlyBase=FBgn0039219|UniProtKB=Q9VC48 Q9VC48 MAP1A PTHR43330:SF7 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metallopeptidase activity#GO:0008237 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0035056|UniProtKB=Q9W116 Q9W116 spz6 PTHR23199:SF7 NEUROTROPHIN 1-RELATED RE45222P molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external stimulus#GO:0009605;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;innate immune response#GO:0045087;developmental process#GO:0032502;response to other organism#GO:0051707;nervous system development#GO:0007399;defense response to other organism#GO:0098542;multicellular organismal process#GO:0032501;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;system development#GO:0048731;anatomical structure development#GO:0048856;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033054|UniProtKB=Q7JRB2 Q7JRB2 Dmel\CG14591 PTHR20948:SF2 TRANSMEMBRANE PROTEIN 164 RH09039P DROME|FlyBase=FBgn0037584|UniProtKB=Q9VHR4 Q9VHR4 Dmel\CG7963 PTHR24404:SF133 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0052774|UniProtKB=Q9W4M2 Q9W4M2 Muc4B PTHR48233:SF4 MUCIN 4B, ISOFORM B-RELATED MUCIN 4B, ISOFORM B-RELATED DROME|FlyBase=FBgn0261341|UniProtKB=E1JI40 E1JI40 verm PTHR45985:SF1 FAMILY NOT NAMED VERMIFORM, ISOFORM I biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;post-embryonic development#GO:0009791;animal gross anatomical part developmental process#GO:0160108;regulation of anatomical structure size#GO:0090066 DROME|FlyBase=FBgn0051126|UniProtKB=Q9VC53 Q9VC53 CG13621 PTHR46229:SF2 BOLA TRANSCRIPTION REGULATOR BOLA-LIKE PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0036874|UniProtKB=Q9VVZ8 Q9VVZ8 brv1 PTHR10877:SF183 POLYCYSTIN FAMILY MEMBER AT14535P-RELATED ion channel#PC00133 DROME|FlyBase=FBgn0036782|UniProtKB=Q9VVP2 Q9VVP2 Dmel\CG7320 PTHR11511:SF5 LARVAL STORAGE PROTEIN/PHENOLOXIDASE FAT-BODY PROTEIN 1-RELATED DROME|FlyBase=FBgn0063496|UniProtKB=A1ZB69 A1ZB69 GstE4 PTHR43969:SF4 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED FI01423P-RELATED catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0032910|UniProtKB=Q9VIG6 Q9VIG6 Dmel\CG9265 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular organelle#GO:0043229 dehydrogenase#PC00092 DROME|FlyBase=FBgn0030053|UniProtKB=Q9W3D5 Q9W3D5 Dmel\CG12081 PTHR46461:SF1 KELCH DOMAIN-CONTAINING PROTEIN 3 KELCH DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;chromatin binding#GO:0003682 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0037901|UniProtKB=Q9VGN7 Q9VGN7 Exd2 PTHR13620:SF133 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2 RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527 DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;RNA metabolic process#GO:0016070;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;response to stimulus#GO:0050896 nucleus#GO:0005634;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0032395|UniProtKB=Q9VKD0 Q9VKD0 Wdr81 PTHR46866:SF1 GH12955P GH12955P biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of transport#GO:0051049 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;late endosome#GO:0005770;vesicle#GO:0031982;intracellular vesicle#GO:0097708 DROME|FlyBase=FBgn0034007|UniProtKB=A1Z9Z7 A1Z9Z7 ND-51L2 PTHR11780:SF10 NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1 NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 oxidoreductase#PC00176 DROME|FlyBase=FBgn0053052|UniProtKB=Q8IQQ4 Q8IQQ4 Gorab PTHR21470:SF29 RAB6-INTERACTING PROTEIN GORAB RAB6-INTERACTING GOLGIN cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 DROME|FlyBase=FBgn0036831|UniProtKB=Q9VVU9 Q9VVU9 Dmel\CG6839 PTHR13966:SF19 ENDONUCLEASE RELATED DNA_RNA NON-SPECIFIC ENDONUCLEASE DOMAIN-CONTAINING PROTEIN-RELATED DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520 apoptotic process#GO:0006915;cell death#GO:0008219;execution phase of apoptosis#GO:0097194;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;catabolic process#GO:0009056;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 DROME|FlyBase=FBgn0028987|UniProtKB=Q9VLQ7 Q9VLQ7 Spn28F PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0033158|UniProtKB=A1Z6X0 A1Z6X0 Dmel\CG12164 PTHR21698:SF4 PROTEIN (PUTATIVE)-RELATED SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0010416|UniProtKB=Q24134 Q24134 TH1 PTHR12144:SF0 NEGATIVE ELONGATION FACTOR D NEGATIVE ELONGATION FACTOR C_D nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleoplasm#GO:0005654 DROME|FlyBase=FBgn0033518|UniProtKB=Q7JX87 Q7JX87 Prx6c PTHR43503:SF3 MCG48959-RELATED 1-CYS PEROXIREDOXIN catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;peroxidase#PC00180 DROME|FlyBase=FBgn0030204|UniProtKB=Q9W2U9 Q9W2U9 Or9a PTHR21137:SF43 ODORANT RECEPTOR ODORANT RECEPTOR 47A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0040344|UniProtKB=Q9V410 Q9V410 Lztr1 PTHR46376:SF1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Ras protein signal transduction#GO:0046578;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 ubiquitin ligase complex#GO:0000151;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;transferase complex#GO:1990234;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0003479|UniProtKB=Q27297 Q27297 spn-A PTHR22942:SF39 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER DNA REPAIR PROTEIN RAD51 HOMOLOG 1 ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to stimulus#GO:0050896;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;protein-containing complex organization#GO:0043933;DNA metabolic process#GO:0006259;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;homologous recombination#GO:0035825;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;DNA repair#GO:0006281;DNA damage response#GO:0006974 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0038140|UniProtKB=Q9VFW5 Q9VFW5 PK2-R1 PTHR24243:SF232 G-PROTEIN COUPLED RECEPTOR PYROKININ 2 RECEPTOR 1-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037310|UniProtKB=Q9VNA0 Q9VNA0 Tim17b1 PTHR10485:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 AT05822P-RELATED transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 transporter#PC00227 DROME|FlyBase=FBgn0036544|UniProtKB=Q9VUV4 Q9VUV4 sff PTHR24343:SF603 SERINE/THREONINE KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;neuron development#GO:0048666;axonogenesis#GO:0007409;cell cycle process#GO:0022402;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;mitotic cell cycle process#GO:1903047;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;mitotic cell cycle phase transition#GO:0044772;system development#GO:0048731;anatomical structure development#GO:0048856;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0035798|UniProtKB=Q9VS89 Q9VS89 frac PTHR24034:SF200 EGF-LIKE DOMAIN-CONTAINING PROTEIN FI18763P1-RELATED cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0261862|UniProtKB=Q9V3K9 Q9V3K9 whd PTHR22589:SF31 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 DROME|FlyBase=FBgn0026679|UniProtKB=Q9W3E1 Q9W3E1 IntS4 PTHR20938:SF0 INTEGRATOR COMPLEX SUBUNIT 4 INTEGRATOR COMPLEX SUBUNIT 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA 3'-end processing#GO:0034472;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;catabolic process#GO:0009056;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0035470|UniProtKB=Q9VZL5 Q9VZL5 Ccz1 PTHR13056:SF0 VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;guanyl-nucleotide exchange factor complex#GO:0032045;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0037915|UniProtKB=Q9VGM0 Q9VGM0 anon-WO0140519.186 PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 extracellular matrix glycoprotein#PC00100 DROME|FlyBase=FBgn0052109|UniProtKB=Q9VU04 Q9VU04 Dmel\CG32109 PTHR14659:SF1 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036988|UniProtKB=Q9VPF8 Q9VPF8 CG5262 PTHR16189:SF0 TRANSMEMBRANE PROTEIN 104-RELATED SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 12-RELATED DROME|FlyBase=FBgn0000153|UniProtKB=Q24062 Q24062 Adc PTHR45677:SF17 GLUTAMATE DECARBOXYLASE-RELATED BLACK, ISOFORM A carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;lyase activity#GO:0016829 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 DROME|FlyBase=FBgn0040383|UniProtKB=Q9V3T2 Q9V3T2 Dmel\CG5254 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0053970|UniProtKB=Q86P18 Q86P18 osy PTHR43038:SF5 ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 OSKYDDAD, ISOFORM A plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0035751|UniProtKB=Q9VS32 Q9VS32 Dmel\CG14829 PTHR21398:SF11 AGAP007094-PA HDC15381-RELATED DROME|FlyBase=FBgn0031430|UniProtKB=Q9VQD0 Q9VQD0 Dmel\CG3528 PTHR33588:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 structural protein#PC00211 DROME|FlyBase=FBgn0032471|UniProtKB=Q9VK40 Q9VK40 Dmel\CG5122 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 DROME|FlyBase=FBgn0052365|UniProtKB=Q9VSB3 Q9VSB3 CG13682 PTHR44054:SF3 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE PDZ DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0021814|UniProtKB=Q9V359 Q9V359 Vps28 PTHR12937:SF0 VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 endosomal transport#GO:0016197;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ESCRT I complex#GO:0000813;membrane#GO:0016020;cytosol#GO:0005829;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0038585|UniProtKB=Q9VEB3 Q9VEB3 Non3 PTHR12728:SF0 BRIX DOMAIN CONTAINING PROTEIN RIBOSOME PRODUCTION FACTOR 2 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 DROME|FlyBase=FBgn0040281|UniProtKB=Q9W0K0 Q9W0K0 Aplip1 PTHR11232:SF18 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER JNK-INTERACTING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;endocytosis#GO:0006897;transport#GO:0006810;membrane invagination#GO:0010324;phagocytosis#GO:0006909;establishment of localization#GO:0051234;import into cell#GO:0098657;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036994|UniProtKB=Q9VPF1 Q9VPF1 CUT8 PTHR28032:SF1 FI02826P FI02826P protein-containing complex binding#GO:0044877;binding#GO:0005488 response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;response to topologically incorrect protein#GO:0035966;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to topologically incorrect protein#GO:0035967;localization#GO:0051179;protein metabolic process#GO:0019538;macromolecule localization#GO:0033036;response to stress#GO:0006950;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;cellular response to misfolded protein#GO:0071218;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965 DROME|FlyBase=FBgn0031817|UniProtKB=Q9VMD3 Q9VMD3 HemK1 PTHR18895:SF74 HEMK METHYLTRANSFERASE MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational termination#GO:0006415;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0264746|UniProtKB=M9PCW4 M9PCW4 Dmel\CG44004 PTHR38926:SF5 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED F-BOX DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 DROME|FlyBase=FBgn0015600|UniProtKB=Q9VQM0 Q9VQM0 toc PTHR24200:SF11 TOUCAN, ISOFORM A TOUCAN, ISOFORM A DROME|FlyBase=FBgn0243513|UniProtKB=Q9VQL3 Q9VQL3 cnir PTHR12290:SF19 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 4 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;vesicle#GO:0031982;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0261530|UniProtKB=Q9VT40 Q9VT40 nbs PTHR12162:SF0 NIBRIN-RELATED NIBRIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684 mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;recombinational repair#GO:0000725;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 DROME|FlyBase=FBgn0033985|UniProtKB=Q8SWZ6 Q8SWZ6 BcDNA:RH51312 PTHR13088:SF3 FAS APOPTOTIC INHIBITORY MOLECULE FAIM FAS APOPTOTIC INHIBITORY MOLECULE 1 regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of programmed cell death#GO:0043069;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066 DROME|FlyBase=FBgn0038535|UniProtKB=Q960Y8 Q960Y8 alt PTHR18939:SF4 RIBOSOME BINDING PROTEIN-1 RIBOSOME-BINDING PROTEIN 1 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0041182|UniProtKB=Q9NFV7 Q9NFV7 Tep2 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease inhibitor#PC00191 DROME|FlyBase=FBgn0053243|UniProtKB=Q7KV19 Q7KV19 Ste:CG33243 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 DROME|FlyBase=FBgn0036004|UniProtKB=Q9VT00 Q9VT00 Jarid2 PTHR10694:SF149 LYSINE-SPECIFIC DEMETHYLASE PROTEIN JUMONJI catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;protein demethylase activity#GO:0140457;dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993 regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 DROME|FlyBase=FBgn0000615|UniProtKB=P28750 P28750 exu PTHR12384:SF2 MATERNAL PROTEIN EXUPERANTIA MATERNAL PROTEIN EXUPERANTIA DROME|FlyBase=FBgn0038810|UniProtKB=Q9VDK7 Q9VDK7 Srp72 PTHR14094:SF9 SIGNAL RECOGNITION PARTICLE 72 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72 binding#GO:0005488;nucleic acid binding#GO:0003676;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021 cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein complex#GO:1990904 DROME|FlyBase=FBgn0002985|UniProtKB=P23803 P23803 odd PTHR14196:SF13 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;embryonic pattern specification#GO:0009880;negative regulation of macromolecule biosynthetic process#GO:0010558;embryo development#GO:0009790;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;tube development#GO:0035295;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0033117|UniProtKB=Q7JUN9 Q7JUN9 Dmel\CG3358 PTHR10060:SF15 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 DROME|FlyBase=FBgn0262160|UniProtKB=Q9VK42 Q9VK42 EP2317 PTHR24403:SF94 ZINC FINGER PROTEIN KUMGANG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0023172|UniProtKB=A1ZAN6 A1ZAN6 RhoGEF2 PTHR45872:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D protein binding#GO:0005515;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;signaling receptor binding#GO:0005102;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0038708|UniProtKB=Q9VDW7 Q9VDW7 Scsalpha2 PTHR11117:SF2 SUCCINYL-COA LIGASE SUBUNIT ALPHA SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 TCA cycle#P00051>Succinyl CoA Synthetase#P01274 DROME|FlyBase=FBgn0037547|UniProtKB=Q9VHW0 Q9VHW0 Dmel\CG7910 PTHR43372:SF3 FATTY-ACID AMIDE HYDROLASE AT07710P-RELATED metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0028858|UniProtKB=Q9V3Q0 Q9V3Q0 BG:DS07486.2 PTHR15454:SF73 NISCHARIN RELATED DYNEIN AXONEMAL LIGHT CHAIN 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;cell projection assembly#GO:0030031;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031279|UniProtKB=Q9VPT2 Q9VPT2 Dmel\CG3544 PTHR10196:SF57 SUGAR KINASE XYLULOSE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200 cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065;kinase#PC00137 Ascorbate degradation#P02729>L-xylulose kinase#P02849 DROME|FlyBase=FBgn0034271|UniProtKB=A1ZAY8 A1ZAY8 Vps50 PTHR13258:SF0 SYNDETIN SYNDETIN SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907 recycling endosome#GO:0055037;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0051812|UniProtKB=Q8IP11 Q8IP11 Tsen2 PTHR21227:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 lyase activity#GO:0016829;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 DROME|FlyBase=FBgn0004811|UniProtKB=Q9VIR9 Q9VIR9 fs(2)ltoPP43 PTHR31196:SF2 RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED DROME|FlyBase=FBgn0000404|UniProtKB=P14785 P14785 CycA PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 kinase activator#PC00138 DROME|FlyBase=FBgn0036514|UniProtKB=Q9VUR2 Q9VUR2 Dmel\CG12301 PTHR14150:SF12 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 UTP14A SMALL SUBUNIT PROCESSOME COMPONENT enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031422|UniProtKB=Q9VQB8 Q9VQB8 PIG-Wa PTHR20661:SF0 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN GLUCOSAMINYL-PHOSPHATIDYLINOSITOL-ACYLTRANSFERASE PIGW acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0029709|UniProtKB=Q9W4K0 Q9W4K0 CHOp24 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Golgi organization#GO:0007030;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0016650|UniProtKB=Q9VEG4 Q9VEG4 Lgr1 PTHR24372:SF74 GLYCOPROTEIN HORMONE RECEPTOR LP13728P molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037330|UniProtKB=Q9VNC1 Q9VNC1 mRpL44 PTHR11207:SF5 RIBONUCLEASE III LARGE RIBOSOMAL SUBUNIT PROTEIN ML44 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 translational elongation#GO:0006414;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;primary miRNA processing#GO:0031053;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;protein biosynthetic process#GO:0160307;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;translation#GO:0006412;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;mitochondrial translation#GO:0032543;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030289|UniProtKB=Q9VZ04 Q9VZ04 GCS1 PTHR10412:SF11 MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE alpha-glucosidase activity#GO:0090599;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121;glucosidase#PC00108 DROME|FlyBase=FBgn0039306|UniProtKB=Q9VBU2 Q9VBU2 RIOK2 PTHR45852:SF1 SER/THR-PROTEIN KINASE RIO2 SERINE_THREONINE-PROTEIN KINASE RIO2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0035207|UniProtKB=E8NHA2 E8NHA2 Herc4 PTHR45622:SF76 UBIQUITIN-PROTEIN LIGASE E3A-RELATED HECT AND RLD DOMAIN CONTAINING E3 UBIQUITIN LIGASE 4, ISOFORM C ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0033371|UniProtKB=A1Z7N3 A1Z7N3 CNT1 PTHR10590:SF24 SODIUM/NUCLEOSIDE COTRANSPORTER CONCENTRATIVE NUCLEOSIDE TRANSPORTER 1-RELATED carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;nucleoside transmembrane transporter activity#GO:0005337;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0033515|UniProtKB=A1Z882 A1Z882 Ir47a PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0011703|UniProtKB=P48591 P48591 RnrL PTHR11573:SF6 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;ATP binding#GO:0005524;small molecule binding#GO:0036094;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553 biosynthetic process#GO:0009058;cellular process#GO:0009987;metabolic process#GO:0008152 oxidoreductase complex#GO:1990204;cytosol#GO:0005829;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921 DROME|FlyBase=FBgn0010909|UniProtKB=Q9W002 Q9W002 msn PTHR48015:SF21 SERINE/THREONINE-PROTEIN KINASE TAO NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0036380|UniProtKB=Q9VU92 Q9VU92 FOHSDR PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0051460|UniProtKB=Q8INQ7 Q8INQ7 CG31460 PTHR32001:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT KCP2 biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 DROME|FlyBase=FBgn0029826|UniProtKB=Q9W454 Q9W454 Dmel\CG6041 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0015360|UniProtKB=Q7KVA1 Q7KVA1 Oxt PTHR46025:SF3 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE OXT transferase#PC00220 DROME|FlyBase=FBgn0023097|UniProtKB=A0A0B4KGE5 A0A0B4KGE5 bon PTHR25462:SF304 BONUS, ISOFORM C-RELATED BONUS, ISOFORM C-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;chromatin binding#GO:0003682;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0028913|UniProtKB=Q9VJS5 Q9VJS5 Dmel\CG3473 PTHR24068:SF141 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;protein K63-linked ubiquitination#GO:0070534;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Ubc13#P01381 DROME|FlyBase=FBgn0039802|UniProtKB=Q9VA37 Q9VA37 dj-1beta PTHR48094:SF28 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PROTEIN DJ-1ALPHA-RELATED catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;cellular detoxification of aldehyde#GO:0110095;carboxylic acid metabolic process#GO:0019752;ketone metabolic process#GO:0042180;cellular response to stimulus#GO:0051716;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;response to chemical#GO:0042221;detoxification#GO:0098754;biosynthetic process#GO:0009058;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;response to stress#GO:0006950;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;response to oxidative stress#GO:0006979;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283 nucleus#GO:0005634;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0030073|UniProtKB=Q8IRN0 Q8IRN0 CG7090 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0038674|UniProtKB=Q9VE10 Q9VE10 Dmel\CG14285 PTHR22844:SF387 F-BOX AND WD40 DOMAIN PROTEIN SIMILARITY TO GTP-BINDING REGULATORY PROTEIN AND WD-REPEAT PROTEIN DROME|FlyBase=FBgn0037312|UniProtKB=Q9VNA3 Q9VNA3 BEST:LD29996 PTHR46809:SF2 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN GH21273P DROME|FlyBase=FBgn0030055|UniProtKB=Q9W3C9 Q9W3C9 Rubicon PTHR45971:SF1 PHOX (PX) DOMAIN-CONTAINING PROTEIN RUBICON, ISOFORM A binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0086785|UniProtKB=Q9VU87 Q9VU87 Vps36 PTHR13128:SF12 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;protein transport#GO:0015031;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104 vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0016917|UniProtKB=Q24151 Q24151 Stat92E PTHR11801:SF70 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND TRANSCRIPTION ACTIVATOR RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cell surface receptor signaling pathway via STAT#GO:0097696;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173 DROME|FlyBase=FBgn0062517|UniProtKB=Q9VZZ8 Q9VZZ8 BcDNA:AT01695 PTHR21490:SF0 ENKURIN-RELATED ENKURIN calmodulin binding#GO:0005516;binding#GO:0005488;protein binding#GO:0005515 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;secretory vesicle#GO:0099503;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cilium#GO:0005929;acrosomal vesicle#GO:0001669;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;vesicle#GO:0031982;cytoplasmic microtubule#GO:0005881;intracellular vesicle#GO:0097708;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0032849|UniProtKB=Q9VIN9 Q9VIN9 mRpS18B PTHR13329:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S18B SMALL RIBOSOMAL SUBUNIT PROTEIN MS40 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 ribosomal protein#PC00202 DROME|FlyBase=FBgn0036906|UniProtKB=Q9VW38 Q9VW38 Dmel\CG14102 PTHR38926:SF84 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED F-BOX DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 DROME|FlyBase=FBgn0038243|UniProtKB=Q9VFI3 Q9VFI3 Dmel\CG8066 PTHR12319:SF2 CYSTATIN-RELATED CYSTATIN-LIKE PROTEIN-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0051475|UniProtKB=Q9VDY9 Q9VDY9 myd PTHR10827:SF98 RETICULOCALBIN 45 KDA CALCIUM-BINDING PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 DROME|FlyBase=FBgn0035540|UniProtKB=M9PEM1 M9PEM1 Syx17 PTHR19957:SF139 SYNTAXIN SYNTAXIN-17 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 SNARE protein#PC00034 DROME|FlyBase=FBgn0038918|UniProtKB=Q9VD62 Q9VD62 Qsox3 PTHR22897:SF8 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;extracellular matrix assembly#GO:0085029;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein folding#GO:0006457;extracellular structure organization#GO:0043062;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0015614|UniProtKB=Q24214 Q24214 CanB2 PTHR45942:SF1 Calcineurin subunit B PROTEIN PHOSPHATASE 3 REGULATORY SUBUNIT B, ALPHA phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;protein phosphatase regulator activity#GO:0019888;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;calcineurin-mediated signaling#GO:0097720;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>Calcineurin#P01446 DROME|FlyBase=FBgn0035422|UniProtKB=Q9VZS5 Q9VZS5 RpL28 PTHR10544:SF0 60S RIBOSOMAL PROTEIN L28 LARGE RIBOSOMAL SUBUNIT PROTEIN EL28 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0016696|UniProtKB=Q9VPC0 Q9VPC0 Pitslre PTHR24056:SF599 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 11A-RELATED catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033192|UniProtKB=A1Z709 A1Z709 Corin PTHR24253:SF192 TRANSMEMBRANE PROTEASE SERINE CORIN, ISOFORM B-RELATED serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0065035|UniProtKB=Q7KUZ2 Q7KUZ2 AlkB PTHR16557:SF12 ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED NUCLEIC ACID DIOXYGENASE ALKBH1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;cation binding#GO:0043169;dioxygenase activity#GO:0051213;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;ion binding#GO:0043167;catalytic activity, acting on RNA#GO:0140098;iron ion binding#GO:0005506;demethylase activity#GO:0032451;catalytic activity, acting on DNA#GO:0140097;ferrous iron binding#GO:0008198;metal ion binding#GO:0046872;binding#GO:0005488 cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;RNA modification#GO:0009451;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0036143|UniProtKB=Q9VTG6 Q9VTG6 Dmel\CG14142 PTHR12473:SF8 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED DROME|FlyBase=FBgn0038717|UniProtKB=Q9VDV8 Q9VDV8 Dmel\CG17751 PTHR24064:SF467 SOLUTE CARRIER FAMILY 22 MEMBER FI01439P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0031955|UniProtKB=Q9VLW2 Q9VLW2 CG14535 PTHR21608:SF7 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN CG14535 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;regulation of biological process#GO:0050789;regulation of neuron migration#GO:2001222 DROME|FlyBase=FBgn0036423|UniProtKB=M9PF86 M9PF86 Dmel\CG3919 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0031988|UniProtKB=Q9VLS8 Q9VLS8 GalT4 PTHR11214:SF379 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0037224|UniProtKB=Q9VMZ5 Q9VMZ5 TwdlF PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 DROME|FlyBase=FBgn0001986|UniProtKB=Q9Y134 Q9Y134 Mtr4 PTHR12131:SF7 ATP-DEPENDENT RNA AND DNA HELICASE EXOSOME RNA HELICASE MTR4 macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0036549|UniProtKB=Q9VUW0 Q9VUW0 Dmel\CG10516 PTHR12245:SF5 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0014877|UniProtKB=P48604 P48604 Roe1 PTHR21237:SF23 GRPE PROTEIN GRPE PROTEIN HOMOLOG, MITOCHONDRIAL enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle lumen#GO:0043233 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0031455|UniProtKB=Q9VQF9 Q9VQF9 Snapin PTHR31305:SF3 SNARE-ASSOCIATED PROTEIN SNAPIN SNARE-ASSOCIATED PROTEIN SNAPIN SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 homeostatic process#GO:0042592;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;regulation of intracellular pH#GO:0051453;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;regulation of pH#GO:0006885;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;vesicle localization#GO:0051648;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;vacuolar transport#GO:0007034;intracellular monoatomic cation homeostasis#GO:0030003;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular transport#GO:0046907;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;lysosomal transport#GO:0007041;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;monoatomic ion homeostasis#GO:0050801;exocytosis#GO:0006887;endosomal transport#GO:0016197;vesicle-mediated transport in synapse#GO:0099003;chemical homeostasis#GO:0048878;regulated exocytosis#GO:0045055 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;BLOC-1 complex#GO:0031083;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular protein-containing complex#GO:0140535;cell junction#GO:0030054;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503 DROME|FlyBase=FBgn0034468|UniProtKB=Q9V8Y2 Q9V8Y2 Obp56a PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0035449|UniProtKB=Q9VZP2 Q9VZP2 Dmel\CG14971 PTHR11132:SF238 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER H1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0014009|UniProtKB=O18333 O18333 Rab2 PTHR47979:SF150 DRAB11-RELATED RAB2A, MEMBER RAS ONCOGENE FAMILY small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein#PC00020;small GTPase#PC00208 PDGF signaling pathway#P00047>Ras#P01154 DROME|FlyBase=FBgn0259212|UniProtKB=Q9VN82 Q9VN82 cno PTHR10398:SF2 AFADIN AFADIN cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell junction organization#GO:0034330;adherens junction organization#GO:0034332;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217;cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;cell junction#GO:0030054;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;cell-cell junction#GO:0005911 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>Afadin#P00146 DROME|FlyBase=FBgn0010240|UniProtKB=Q08832 Q08832 Lcch3 PTHR18945:SF916 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2 transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 transport#GO:0006810;chloride transport#GO:0006821;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic anion transmembrane transport#GO:0098656;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;localization#GO:0051179;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916 signaling receptor complex#GO:0043235;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0024987|UniProtKB=O76876 O76876 ssx PTHR24012:SF885 RNA BINDING PROTEIN PROTEIN SEX-LETHAL RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0262560|UniProtKB=Q9V7P1 Q9V7P1 wcd PTHR18359:SF0 WD-REPEAT PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0014906|UniProtKB=Q24093 Q24093 Hydr2 PTHR10794:SF45 ABHYDROLASE DOMAIN-CONTAINING PROTEIN MONOACYLGLYCEROL LIPASE ABHD2 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 response to steroid hormone#GO:0048545;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;primary metabolic process#GO:0044238;steroid hormone receptor signaling pathway#GO:0043401;anatomical structure maturation#GO:0071695;cellular response to stimulus#GO:0051716;germ cell development#GO:0007281;regulation of cellular process#GO:0050794;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;neutral lipid catabolic process#GO:0046461;cell maturation#GO:0048469;monocarboxylic acid biosynthetic process#GO:0072330;developmental maturation#GO:0021700;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;small molecule catabolic process#GO:0044282;cellular response to steroid hormone stimulus#GO:0071383;signal transduction#GO:0007165;lipid catabolic process#GO:0016042;cellular process#GO:0009987;cellular response to lipid#GO:0071396;cell communication#GO:0007154;developmental process involved in reproduction#GO:0003006;carboxylic acid biosynthetic process#GO:0046394;catabolic process#GO:0009056;reproductive process#GO:0022414;spermatogenesis#GO:0007283;developmental process#GO:0032502;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;neutral lipid metabolic process#GO:0006638;cellular developmental process#GO:0048869;carboxylic acid catabolic process#GO:0046395;male gamete generation#GO:0048232;fatty acid biosynthetic process#GO:0006633;oxoacid metabolic process#GO:0043436;glycerolipid catabolic process#GO:0046503;spermatid differentiation#GO:0048515;hormone-mediated signaling pathway#GO:0009755;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;gamete generation#GO:0007276;signaling#GO:0023052;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;response to hormone#GO:0009725;response to chemical#GO:0042221;response to lipid#GO:0033993;sperm capacitation#GO:0048240 sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729 serine protease#PC00203;protease#PC00190 DROME|FlyBase=FBgn0037920|UniProtKB=Q7KSP9 Q7KSP9 Dmel\CG14710 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0002878|UniProtKB=Q9VY97 Q9VY97 mus101 PTHR13561:SF20 DNA REPLICATION REGULATOR DPB11-RELATED DNA TOPOISOMERASE 2-BINDING PROTEIN 1 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0000636|UniProtKB=P15278 P15278 Fas3 PTHR23277:SF108 NECTIN-RELATED FASCICLIN-3 protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;adherens junction#GO:0005912;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0031925|UniProtKB=Q9VLZ7 Q9VLZ7 Cyp4d21 PTHR24291:SF187 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4AE1-RELATED oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0052506|UniProtKB=Q8IQ30 Q8IQ30 tbc PTHR22957:SF502 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0285926|UniProtKB=M9NF14 M9NF14 Imp PTHR10288:SF338 KH DOMAIN CONTAINING RNA BINDING PROTEIN IGF-II MRNA-BINDING PROTEIN, ISOFORM L binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 developmental process#GO:0032502;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0053051|UniProtKB=Q86BI8 Q86BI8 Polr3G PTHR15367:SF2 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0263831|UniProtKB=Q9VRJ0 Q9VRJ0 Gen PTHR11081:SF70 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE GEN HOMOLOG 1 four-way junction DNA binding#GO:0000400;nuclease activity#GO:0004518;DNA binding#GO:0003677;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;binding#GO:0005488;nucleic acid binding#GO:0003676;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0028870|UniProtKB=Q9V3K5 Q9V3K5 Dmel\CG4691 PTHR20977:SF0 AT13385P-RELATED AT13385P-RELATED DROME|FlyBase=FBgn0085396|UniProtKB=A8DYR8 A8DYR8 CG13141 PTHR46255:SF3 SHORT STATURE HOMEOBOX HOMEOBOX PROTEIN UNC-4 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0032096|UniProtKB=Q9VLE5 Q9VLE5 Or30a PTHR21137:SF3 ODORANT RECEPTOR ODORANT RECEPTOR 30A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037144|UniProtKB=Q9VNW8 Q9VNW8 Dmel\CG7458 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER FI24011P1-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034599|UniProtKB=Q9W2K3 Q9W2K3 hng1 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0000109|UniProtKB=P12426 P12426 Aprt PTHR32315:SF3 ADENINE PHOSPHORIBOSYLTRANSFERASE ADENINE PHOSPHORIBOSYLTRANSFERASE purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;pentosyltransferase activity#GO:0016763;cation binding#GO:0043169 carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220 Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 DROME|FlyBase=FBgn0037960|UniProtKB=Q9VGG8 Q9VGG8 mthl5 PTHR46953:SF2 G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED G-PROTEIN COUPLED RECEPTOR MTH-LIKE 5-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0085430|UniProtKB=Q9VWN9 Q9VWN9 Dora PTHR22619:SF1 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0030612|UniProtKB=Q9VXY3 Q9VXY3 Dbct PTHR43178:SF18 LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED CHAIN ALPHA_KETOACID DEHYDROGENASE COMPLEX LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0030573|UniProtKB=Q9VY27 Q9VY27 nmdyn-D6 PTHR46161:SF1 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE 5 nucleotide kinase#PC00172;kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 DROME|FlyBase=FBgn0040958|UniProtKB=Q9VLL9 Q9VLL9 Peritrophin-15b PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0034438|UniProtKB=Q8MT48 Q8MT48 CG9416-PA PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0031717|UniProtKB=Q9VMP9 Q9VMP9 Gnpda PTHR11280:SF5 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE DEAMINASE catalytic activity#GO:0003824;binding#GO:0005488;identical protein binding#GO:0042802;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;protein binding#GO:0005515;hydrolase activity#GO:0016787 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carbohydrate derivative metabolic process#GO:1901135;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino sugar catabolic process#GO:0046348 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 DROME|FlyBase=FBgn0052833|UniProtKB=Q8MLS8 Q8MLS8 BcDNA:GH11992 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0027841|UniProtKB=Q9VE52 Q9VE52 CstF64 PTHR45735:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 DROME|Gene_ORFName=Dmel_CG46517|UniProtKB=A0ACD4DAV2 A0ACD4DAV2 CG46517 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 DROME|FlyBase=FBgn0261381|UniProtKB=Q9VTM5 Q9VTM5 mtTFB1 PTHR11727:SF30 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transcription regulator activity#GO:0140110;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433 ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;methylation#GO:0032259;RNA metabolic process#GO:0016070;rRNA modification#GO:0000154;DNA-templated transcription initiation#GO:0006352;ribonucleoprotein complex biogenesis#GO:0022613;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;mitochondrial RNA metabolic process#GO:0000959;rRNA processing#GO:0006364;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;mitochondrial transcription#GO:0006390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0008651|UniProtKB=A0A0B4KH37 A0A0B4KH37 lbl PTHR24336:SF8 TRANSCRIPTION FACTOR LBX LADYBIRD EARLY-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0032387|UniProtKB=Q9VKD9 Q9VKD9 Dmel\CG16965 PTHR11051:SF8 GLYCOSYL HYDROLASE-RELATED MIP16835P1 catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975 hydrolase#PC00121;glycosidase#PC00110 DROME|FlyBase=FBgn0266672|UniProtKB=Q9VNH6 Q9VNH6 Sec8 PTHR14146:SF4 EXOCYST COMPLEX COMPONENT 4 EXOCYST COMPLEX COMPONENT 4 secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;secretion by cell#GO:0032940;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;export from cell#GO:0140352;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987 cell cortex#GO:0005938;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;growth cone#GO:0030426;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;exocyst#GO:0000145;cytoplasm#GO:0005737;cell junction#GO:0030054;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0051874|UniProtKB=Q8IPD2 Q8IPD2 Fum4 PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 DROME|FlyBase=FBgn0033754|UniProtKB=Q7JYV7 Q7JYV7 Ak6 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;ribonucleotide binding#GO:0032553;kinase activity#GO:0016301;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;nucleobase-containing compound kinase activity#GO:0019205;ATP binding#GO:0005524;binding#GO:0005488;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0266758|UniProtKB=A0A0B4K6F9 A0A0B4K6F9 Esyt2 PTHR45761:SF1 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;cation binding#GO:0043169;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylcholine binding#GO:0031210 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0051793|UniProtKB=Q8MT77 Q8MT77 CG17338 PTHR24223:SF448 ATP-BINDING CASSETTE SUB-FAMILY C FI20146P1-RELATED localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0030963|UniProtKB=Q9VWP7 Q9VWP7 Dmel\CG7101 PTHR24406:SF23 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0031873|UniProtKB=Q9VM63 Q9VM63 Gas41 PTHR23195:SF15 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 4 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 general transcription factor#PC00259 DROME|FlyBase=FBgn0035393|UniProtKB=Q9VZV8 Q9VZV8 Dmel\CG16753 PTHR31109:SF2 PROTEIN FAM207A RIBOSOME BIOGENESIS PROTEIN SLX9 HOMOLOG DROME|FlyBase=FBgn0038451|UniProtKB=Q9VES5 Q9VES5 CT34717 PTHR11011:SF60 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0086784|UniProtKB=Q8IGJ0 Q8IGJ0 stmA PTHR12444:SF8 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG CMP44E protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0032798|UniProtKB=Q9VIU8 Q9VIU8 Dmel\CG10132 PTHR19871:SF37 BETA TRANSDUCIN-RELATED PROTEIN GH25853P DROME|FlyBase=FBgn0040260|UniProtKB=Q9VJH8 Q9VJH8 Ugt37D1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0034083|UniProtKB=A1ZAB1 A1ZAB1 lbk PTHR24373:SF417 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LAMBIK signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0028482|UniProtKB=Q9U4G1 Q9U4G1 bdl PTHR10075:SF78 BASIGIN RELATED PROTEIN BORDERLESS cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0001168|UniProtKB=P14003 P14003 hry PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED PROTEIN HAIRY transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 DROME|FlyBase=FBgn0037614|UniProtKB=Q9VHN0 Q9VHN0 TMEM216 PTHR13531:SF0 GEO07735P1-RELATED-RELATED GEO07735P1-RELATED cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;cilium#GO:0005929 DROME|FlyBase=FBgn0035667|UniProtKB=Q9VRS9 Q9VRS9 Jon65Ai PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0036643|UniProtKB=Q9VV76 Q9VV76 Syx8 PTHR19957:SF285 SYNTAXIN SYNTAXIN-8 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane fusion#GO:0061025;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;endomembrane system#GO:0012505;membrane protein complex#GO:0098796;membrane#GO:0016020 SNARE protein#PC00034 DROME|FlyBase=FBgn0263025|UniProtKB=Q9VB06 Q9VB06 HSPBAP1 PTHR12461:SF43 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HSPB1-ASSOCIATED PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030420|UniProtKB=Q9VYJ5 Q9VYJ5 pira PTHR46896:SF3 SENTRIN-SPECIFIC PROTEASE FI06413P-RELATED cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0010422|UniProtKB=P20232 P20232 TfIIS PTHR11477:SF53 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN IP08861P-RELATED transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0259984|UniProtKB=Q9VJW9 Q9VJW9 kuz PTHR45702:SF2 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;membrane protein ectodomain proteolysis#GO:0006509;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 DROME|FlyBase=FBgn0066101|UniProtKB=A8JRD0 A8JRD0 LpR1 PTHR24270:SF68 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LD11117P-RELATED transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transfer/carrier protein#PC00219;apolipoprotein#PC00052 DROME|FlyBase=FBgn0037846|UniProtKB=Q9VGV5 Q9VGV5 Dmel\CG6574 PTHR10686:SF18 FOLATE TRANSPORTER IP11787P-RELATED transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0034694|UniProtKB=Q9W293 Q9W293 Plekhm1 PTHR12326:SF12 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY AND RUN DOMAIN CONTAINING M1 DROME|FlyBase=FBgn0261269|UniProtKB=A1Z9N6 A1Z9N6 conv PTHR45617:SF133 LEUCINE RICH REPEAT FAMILY PROTEIN ACID LABILE SUBUNIT scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039616|UniProtKB=Q9VAR7 Q9VAR7 Dmel\CG11828 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0037186|UniProtKB=A8E6R2 A8E6R2 Dmel\CG11241 PTHR45688:SF3 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL DROME|FlyBase=FBgn0031149|UniProtKB=Q9VRE0 Q9VRE0 Stt3A PTHR13872:SF43 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein modification process#GO:0036211;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0037359|UniProtKB=Q9VNG0 Q9VNG0 MED27 PTHR13130:SF4 34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 transcription cofactor#PC00217 DROME|FlyBase=FBgn0037172|UniProtKB=Q9VNT3 Q9VNT3 ND-B14.5AL PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775 transporter complex#GO:1990351;organelle membrane#GO:0031090;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036039|UniProtKB=Q95SX8 Q95SX8 Naa60 PTHR14744:SF15 N-ALPHA-ACETYLTRANSFERASE 60 N-ALPHA-ACETYLTRANSFERASE 60 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;acetyltransferase#PC00038 DROME|FlyBase=FBgn0037916|UniProtKB=Q9VGL9 Q9VGL9 Dmel\CG5342 PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 extracellular matrix glycoprotein#PC00100 DROME|FlyBase=FBgn0037956|UniProtKB=Q9VGH2 Q9VGH2 6959 PTHR24364:SF18 LP06937P LP06937P cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0033753|UniProtKB=Q9V6D6 Q9V6D6 Cyp301a1 PTHR24305:SF30 CYTOCHROME P450 CYTOCHROME P450 301A1, MITOCHONDRIAL-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0051155|UniProtKB=Q9VFB5 Q9VFB5 Polr2G PTHR12709:SF4 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0260400|UniProtKB=P16914 P16914 elav PTHR10352:SF27 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G PROTEIN ELAV nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 DROME|FlyBase=FBgn0039227|UniProtKB=Q9VC36 Q9VC36 polybromo PTHR16062:SF19 SWI/SNF-RELATED PROTEIN POLYBROMO-1 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;RSC-type complex#GO:0016586 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0002733|UniProtKB=Q01069 Q01069 E(spl)mbeta-HLH PTHR10985:SF12 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED ENHANCER OF SPLIT M3 PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 DROME|FlyBase=FBgn0039194|UniProtKB=Q9VC81 Q9VC81 Dmel\CG13614 PTHR21253:SF0 F-BOX ONLY PROTEIN 11-RELATED F-BOX ONLY PROTEIN 11-RELATED DROME|FlyBase=FBgn0022960|UniProtKB=A1Z6S7 A1Z6S7 vimar PTHR10957:SF1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 GTPASE-GDP DISSOCIATION STIMULATOR VIMAR cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0045474|UniProtKB=Q8IPU5 Q8IPU5 Gr77a PTHR21143:SF123 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR FOR SUGAR TASTE 43A-RELATED dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;neuron projection#GO:0043005;cell body#GO:0044297;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038833|UniProtKB=Q9VDH9 Q9VDH9 Dmel\CG15696 PTHR24327:SF81 HOMEOBOX PROTEIN HOMEOTIC PROTEIN DISTAL-LESS-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0052087|UniProtKB=Q8MR82 Q8MR82 CG7308 PTHR10281:SF121 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;intramembrane lipid carrier activity#GO:0140303 catabolic process#GO:0009056;cellular component organization#GO:0016043;Golgi organization#GO:0007030;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0039117|UniProtKB=Q9VCH8 Q9VCH8 tst PTHR12131:SF34 ATP-DEPENDENT RNA AND DNA HELICASE SUPERKILLER COMPLEX PROTEIN 2 helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0063670|UniProtKB=Q8MQI6 Q8MQI6 CG40228 PTHR20934:SF0 TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175 transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DROME|FlyBase=FBgn0039309|UniProtKB=A0A1Z1CH25 A0A1Z1CH25 Dmel\CG11891 PTHR11012:SF13 PROTEIN KINASE-LIKE DOMAIN-CONTAINING AT27361P-RELATED DROME|FlyBase=FBgn0041342|UniProtKB=Q7K4C7 Q7K4C7 Pcyt1 PTHR10739:SF13 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;lipid binding#GO:0008289;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phospholipid binding#GO:0005543;nucleotidyltransferase activity#GO:0016779;phosphatidylcholine binding#GO:0031210 transferase#PC00220 DROME|FlyBase=FBgn0034854|UniProtKB=Q9W1R3 Q9W1R3 Golgin245 PTHR19327:SF0 GOLGIN GOLGIN SUBFAMILY A MEMBER 4 enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0033984|UniProtKB=Q9V780 Q9V780 Lap1 PTHR47186:SF61 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 PROTEIN LAP1 DROME|FlyBase=FBgn0085415|UniProtKB=Q1ECA0 Q1ECA0 CG14497 PTHR23107:SF0 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN IP09280P transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0284255|UniProtKB=Q9VMH2 Q9VMH2 Arpc4 PTHR22629:SF0 ARP2/3 COMPLEX 20 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization#GO:0016043;organelle organization#GO:0006996;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 DROME|FlyBase=FBgn0260960|UniProtKB=Q9VV87 Q9VV87 Baldspot PTHR11157:SF17 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 6 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0051453|UniProtKB=Q8SX76 Q8SX76 pch2 PTHR45991:SF1 PACHYTENE CHECKPOINT PROTEIN 2 PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;regulation of reproductive process#GO:2000241;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organelle fission#GO:0048285;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;reproductive process#GO:0022414;homologous recombination#GO:0035825;regulation of cellular process#GO:0050794 chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|Gene_ORFName=Dmel_CG31038|UniProtKB=A0ACA5YM07 A0ACA5YM07 CG31038 PTHR46949:SF1 LEUCINE REPEAT ADAPTER PROTEIN 25 AT07979P2 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0004646|UniProtKB=P27716 P27716 ogre PTHR11893:SF39 INNEXIN INNEXIN INX1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 gap junction#PC00105 DROME|FlyBase=FBgn0033451|UniProtKB=A1Z803 A1Z803 Marc PTHR14237:SF19 MOLYBDOPTERIN COFACTOR SULFURASE MOSC FI02892P DROME|FlyBase=FBgn0020545|UniProtKB=O18391 O18391 kraken PTHR43329:SF164 EPOXIDE HYDROLASE SERINE HYDROLASE-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 DROME|FlyBase=FBgn0265052|UniProtKB=A0A0B4KF40 A0A0B4KF40 St3 PTHR11783:SF180 SULFOTRANSFERASE SULT GH11818P-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039440|UniProtKB=Q9VBD6 Q9VBD6 TwdlJ PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035504|UniProtKB=Q4V5U6 Q4V5U6 Teh4 PTHR12335:SF3 TIPE PROTEIN TEMPERATURE-INDUCED PARALYTIC E IP11896P transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of localization#GO:0032879 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0027599|UniProtKB=Q9W0X8 Q9W0X8 BcDNA:GH03108 PTHR44029:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 DROME|FlyBase=FBgn0039602|UniProtKB=Q9VAT1 Q9VAT1 Dmel\CG1647 PTHR24406:SF24 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN ZIPIC zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0263603|UniProtKB=Q86BI3 Q86BI3 Zn72D PTHR45762:SF3 ZINC FINGER RNA-BINDING PROTEIN ZINC-FINGER PROTEIN AT 72D, ISOFORM B double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034903|UniProtKB=B7YZP6 B7YZP6 sona PTHR11905:SF249 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN SOL NARAE, ISOFORM C catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0086448|UniProtKB=Q8IR17 Q8IR17 PIG-Q PTHR21329:SF3 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0038551|UniProtKB=Q9VEF0 Q9VEF0 Odj PTHR24390:SF79 ZINC FINGER PROTEIN LD33778P DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0032450|UniProtKB=Q9VK63 Q9VK63 Dmel\CG5776 PTHR23077:SF27 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0034061|UniProtKB=Q7K1Z5 Q7K1Z5 Ufc1 PTHR12921:SF0 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;catabolic process#GO:0009056;macroautophagy#GO:0016236;reticulophagy#GO:0061709;response to stress#GO:0006950;autophagy#GO:0006914;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0032796|UniProtKB=M9PBE1 M9PBE1 cyst PTHR13944:SF21 AGAP007712-PA CYSTS, ISOFORM C molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124 DROME|FlyBase=FBgn0034187|UniProtKB=A1ZAP7 A1ZAP7 Mov10 PTHR10887:SF419 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV10L1 ISOFORM X1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441 intracellular organelle#GO:0043229;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226 RNA helicase#PC00032 DROME|FlyBase=FBgn0005659|UniProtKB=P29775 P29775 Ets98B PTHR11849:SF320 ETS DNA-BINDING PROTEIN D-ETS-4 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0085387|UniProtKB=P33085 P33085 shakB PTHR11893:SF40 INNEXIN INNEXIN SHAKING-B transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 gap junction#PC00105 DROME|FlyBase=FBgn0051259|UniProtKB=Q9VHQ4 Q9VHQ4 CG11740 PTHR12459:SF27 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 DROME|FlyBase=FBgn0031631|UniProtKB=Q9VR29 Q9VR29 cg3225 PTHR18934:SF136 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX35-RELATED ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;helicase activity#GO:0004386 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0038118|UniProtKB=Q8INH7 Q8INH7 timeout PTHR22940:SF4 TIMEOUT/TIMELESS-2 PROTEIN TIMELESS HOMOLOG DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of DNA-templated DNA replication#GO:0090329;DNA replication#GO:0006260;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;negative regulation of DNA-templated DNA replication#GO:2000104;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;DNA integrity checkpoint signaling#GO:0031570;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0061198|UniProtKB=Q8MLQ0 Q8MLQ0 HSPC300 PTHR33668:SF3 PROTEIN BRICK1 PROTEIN BRICK1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 regulation of cell projection organization#GO:0031344;regulation of anatomical structure size#GO:0090066;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;regulation of biological quality#GO:0065008;regulation of cell projection assembly#GO:0060491;cellular component organization#GO:0016043;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cellular component biogenesis#GO:0044087 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0032233|UniProtKB=Q9VKX8 Q9VKX8 dpr19 PTHR23279:SF2 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 19, ISOFORM A cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020 DROME|FlyBase=FBgn0038115|UniProtKB=Q9VFZ4 Q9VFZ4 Dmel\CG7966 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 DROME|FlyBase=FBgn0051624|UniProtKB=Q9VIE3 Q9VIE3 CG17401 PTHR24205:SF16 FOUR AND A HALF LIM DOMAINS PROTEIN GH01042P-RELATED transcription cofactor#PC00217 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 DROME|FlyBase=FBgn0283476|UniProtKB=Q9VWZ3 Q9VWZ3 Dhc16F PTHR10676:SF339 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 6 protein binding#GO:0005515;microtubule motor activity#GO:0003777;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dynein complex#GO:0030286 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0039851|UniProtKB=Q9V9X1 Q9V9X1 mey PTHR47327:SF1 FI18240P1-RELATED FI18240P1-RELATED anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 DROME|FlyBase=FBgn0030511|UniProtKB=Q9I7S2 Q9I7S2 Dmel\CG11158 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 DROME|FlyBase=FBgn0037288|UniProtKB=Q9VN71 Q9VN71 Jhbp3 PTHR11008:SF14 PROTEIN TAKEOUT-LIKE PROTEIN JUVENILE HORMONE BINDING PROTEIN 3, ISOFORM A circadian rhythm#GO:0007623;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0040375|UniProtKB=Q9W4Y0 Q9W4Y0 EG:BACR25B3.6 PTHR31400:SF1 GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1 PROTEIN GUCD1 guanylate cyclase#PC00114 DROME|FlyBase=FBgn0069923|UniProtKB=Q8SY69 Q8SY69 Mic10b PTHR21304:SF0 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0263040|UniProtKB=A0A0B4K687 A0A0B4K687 SPH73 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0004620|UniProtKB=Q9VMP4 Q9VMP4 GluRIIA PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857 regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 DROME|FlyBase=FBgn0050105|UniProtKB=A1ZAW6 A1ZAW6 BcDNA:RE11282 PTHR47204:SF1 OS02G0168900 PROTEIN PHAGE TAIL PROTEIN DROME|FlyBase=FBgn0033365|UniProtKB=A1Z7M7 A1Z7M7 SP54 PTHR24253:SF46 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE P83 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0038296|UniProtKB=Q9VFC4 Q9VFC4 Kpc1 PTHR13363:SF5 RING FINGER AND SRY DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF123 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0051202|UniProtKB=Q8IMK0 Q8IMK0 alpha-Man-Ic PTHR11742:SF6 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033015|UniProtKB=Q7K3G5 Q7K3G5 d4 PTHR45888:SF5 HL01030P-RELATED D4, ISOFORM A transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 DROME|FlyBase=FBgn0265271|UniProtKB=Q9VGJ4 Q9VGJ4 Dmel\CG14717 PTHR46118:SF4 PROTEIN ABHD11 SN-1-SPECIFIC DIACYLGLYCEROL LIPASE ABHD11 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0031766|UniProtKB=Q9VMI8 Q9VMI8 Dmel\CG9117 PTHR23200:SF48 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0052103|UniProtKB=Q0E8F2 Q0E8F2 SCaMC PTHR24089:SF769 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SCAMC transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;localization#GO:0051179;carbohydrate derivative transport#GO:1901264;transport#GO:0006810;nitrogen compound transport#GO:0071705 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0259994|UniProtKB=E1JJE6 E1JJE6 OtopLa PTHR21522:SF62 PROTON CHANNEL OTOP OTOPETRIN-LIKE A, ISOFORM C monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0266756|UniProtKB=A0A0B4K657 A0A0B4K657 btsz PTHR45716:SF2 BITESIZE, ISOFORM I BITESIZE, ISOFORM I protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 exocytosis#GO:0006887;secretion by cell#GO:0032940;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0036038|UniProtKB=Q9VT41 Q9VT41 defl PTHR13322:SF2 C1ORF73 PROTEIN INTEGRATOR COMPLEX SUBUNIT 7 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;integrator complex#GO:0032039 DROME|FlyBase=FBgn0039732|UniProtKB=Q9VAC7 Q9VAC7 Dmel\CG15525 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0030251|UniProtKB=Q9VZ49 Q9VZ49 Arlr PTHR12439:SF42 PLACENTAL PROTEIN 11-RELATED ENDORIBONUCLEASE ARLR-RELATED catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional gene silencing#GO:0016441 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033214|UniProtKB=Q7JYK2 Q7JYK2 Dmel\CG1941 PTHR12317:SF0 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0287767|UniProtKB=Q8MT58 Q8MT58 Cndp2 PTHR43270:SF4 BETA-ALA-HIS DIPEPTIDASE CARNOSINE DIPEPTIDASE 2, ISOFORM A peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153 DROME|FlyBase=FBgn0052569|UniProtKB=Q8IR09 Q8IR09 TwdlZ PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 DROME|FlyBase=FBgn0035645|UniProtKB=Q9VRQ8 Q9VRQ8 Dmel\CG5592 PTHR24064:SF316 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0041247|UniProtKB=Q9VM09 Q9VM09 Gr28a PTHR21143:SF104 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 8A-RELATED neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0085319|UniProtKB=A8JRA0 A8JRA0 Dmel\CG34290 PTHR24276:SF97 POLYSERASE-RELATED GH13245P2-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 serine protease#PC00203;protein modifying enzyme#PC00260 DROME|Gene_ORFName=Dmel_CG2221|UniProtKB=A0ACD4DAV1 A0ACD4DAV1 l(1)G0289 PTHR13055:SF12 TUMOR ENDOTHELIAL MARKER 7 RELATED LETHAL (1) G0289, ISOFORM D DROME|FlyBase=FBgn0024913|UniProtKB=O61643 O61643 Actbeta PTHR11848:SF309 TGF-BETA FAMILY INHIBIN BETA CHAIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;Activin beta signaling pathway#P06210>activinbeta full length#P06232;TGF-beta signaling pathway#P00052>TGFbeta#P01286;Activin beta signaling pathway#P06210>activin beta#P06234 DROME|FlyBase=FBgn0035880|UniProtKB=Q8IQA9 Q8IQA9 Culd PTHR24270:SF62 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED CD320 ANTIGEN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 apolipoprotein#PC00052;transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0010241|UniProtKB=Q5BI62 Q5BI62 Mdr50 PTHR24221:SF645 ATP-BINDING CASSETTE SUB-FAMILY B ABC-TYPE XENOBIOTIC TRANSPORTER primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0035168|UniProtKB=Q9W0M1 Q9W0M1 Cep290 PTHR18879:SF21 CENTROSOMAL PROTEIN OF 290 KDA CENTROSOMAL PROTEIN CEP290 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;ciliary transition zone assembly#GO:1905349;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;plasma membrane bounded cell projection#GO:0120025;centriolar satellite#GO:0034451;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869 DROME|FlyBase=FBgn0030576|UniProtKB=Q9VY22 Q9VY22 Dmel\CG15890 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0039848|UniProtKB=Q9V9X5 Q9V9X5 Loxl1 PTHR45817:SF4 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE-LIKE-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0027568|UniProtKB=Q9VKY2 Q9VKY2 Cand1 PTHR12696:SF5 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;cellular component assembly#GO:0022607;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein modification process#GO:0036211;protein-containing complex assembly#GO:0065003;protein modification by small protein conjugation#GO:0032446 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0032391|UniProtKB=Q9VKD5 Q9VKD5 escl PTHR10253:SF12 POLYCOMB PROTEIN POLYCOMB PROTEIN EED molecular function activator activity#GO:0140677;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;chromatin binding#GO:0003682;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0015919|UniProtKB=P54269 P54269 caup PTHR11211:SF40 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN ARAUCAN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0042205|UniProtKB=Q9I7J8 Q9I7J8 Dmel\CG18764 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0037085|UniProtKB=B6VQ99 B6VQ99 Neu2 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0052751|UniProtKB=Q8IRR1 Q8IRR1 CG32751 PTHR10609:SF28 BIOTINIDASE-RELATED CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;metabolic process#GO:0008152 hydrolase#PC00121 DROME|FlyBase=FBgn0039073|UniProtKB=Q9VCM8 Q9VCM8 Dmel\CG4408 PTHR11705:SF60 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B ZINC CARBOXYPEPTIDASE A 1 metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0046878|UniProtKB=Q9VNL1 Q9VNL1 Obp83cd PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0030298|UniProtKB=Q9VYZ1 Q9VYZ1 Or10a PTHR21137:SF26 ODORANT RECEPTOR ODORANT RECEPTOR 10A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0037460|UniProtKB=Q4V5H8 Q4V5H8 sowi PTHR23055:SF190 CALCIUM BINDING PROTEINS AT17667P-RELATED ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 DROME|FlyBase=FBgn0031374|UniProtKB=M9PB01 M9PB01 Wdr62 PTHR45589:SF5 WD REPEAT DOMAIN 62, ISOFORM G WD REPEAT DOMAIN 62, ISOFORM G biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 DROME|FlyBase=FBgn0266724|UniProtKB=Q9VUZ1 Q9VUZ1 Trs20 PTHR12403:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197 TRAPP complex#GO:0030008;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0027948|UniProtKB=Q9VEZ3 Q9VEZ3 msps PTHR12609:SF0 MICROTUBULE ASSOCIATED PROTEIN XMAP215 CYTOSKELETON-ASSOCIATED PROTEIN 5 binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;protein-containing complex organization#GO:0043933;microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;protein polymerization#GO:0051258;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;establishment or maintenance of cell polarity#GO:0007163 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule end#GO:1990752;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0031318|UniProtKB=Q9VPY4 Q9VPY4 Dmel\CG4887 PTHR13948:SF3 RNA-BINDING PROTEIN FI21118P1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0023388|UniProtKB=M9ND00 M9ND00 Dap160 PTHR11216:SF181 EH DOMAIN DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;endosomal transport#GO:0016197;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;intracellular transport#GO:0046907;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;synaptic vesicle endocytosis#GO:0048488;cellular localization#GO:0051641;localization#GO:0051179 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0035203|UniProtKB=Q9W0H6 Q9W0H6 Acat2 PTHR18919:SF107 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0262007|UniProtKB=Q961K4 Q961K4 Srg2 PTHR23529:SF2 GH19118P-RELATED GH19118P-RELATED DROME|FlyBase=FBgn0034327|UniProtKB=Q9V8F3 Q9V8F3 CG14505 PTHR12490:SF6 GSK3B-INTERACTING PROTEIN GEO05133P1-RELATED protein binding#GO:0005515;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase A binding#GO:0051018;binding#GO:0005488 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0032083|UniProtKB=M9PCF9 M9PCF9 Dmel\CG9541 PTHR23359:SF194 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 5-LIKE PROTEIN kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776 carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;nucleoside diphosphate metabolic process#GO:0009132;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ribonucleoside diphosphate metabolic process#GO:0009185 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 nucleotide kinase#PC00172;kinase#PC00137 DROME|FlyBase=FBgn0266674|UniProtKB=Q9VDE6 Q9VDE6 Sec15 PTHR12702:SF0 SEC15 EXOCYST COMPLEX COMPONENT 6 transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;cytoplasm#GO:0005737;exocyst#GO:0000145;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0264894|UniProtKB=M9PDE7 M9PDE7 CG6108 PTHR21601:SF0 SPA2 PROTEIN SCAFFOLD PROTEIN SPA2 signaling adaptor activity#GO:0035591;MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein complex scaffold activity#GO:0140378 intracellular protein localization#GO:0008104;localization#GO:0051179;cellular process#GO:0009987;establishment of cell polarity#GO:0030010;macromolecule localization#GO:0033036;establishment or maintenance of cell polarity#GO:0007163 actomyosin contractile ring#GO:0005826;mitotic actomyosin contractile ring#GO:0110085;cytoskeleton#GO:0005856;contractile ring#GO:0070938;cell pole#GO:0060187;membraneless organelle#GO:0043228;cell periphery#GO:0071944;mating projection tip#GO:0043332;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell tip#GO:0051286;organelle#GO:0043226 DROME|FlyBase=FBgn0039461|UniProtKB=Q9VBA6 Q9VBA6 Dmel\CG5500 PTHR21193:SF3 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 DROME|FlyBase=FBgn0267339|UniProtKB=P83100 P83100 p38c PTHR24055:SF615 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE P38A-RELATED catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;FGF signaling pathway#P00021>p38#P00644;TGF-beta signaling pathway#P00052>P38#P01275;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Parkinson disease#P00049>p38 MAPK#P01212 DROME|FlyBase=FBgn0033354|UniProtKB=A1Z7L1 A1Z7L1 Fanci PTHR21818:SF0 BC025462 PROTEIN FANCONI ANEMIA GROUP I PROTEIN regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;DNA damage response#GO:0006974;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA repair complex#GO:1990391;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0259168|UniProtKB=P49657 P49657 mnb PTHR24058:SF12 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1B transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0037772|UniProtKB=Q9VH46 Q9VH46 Spn85F PTHR11461:SF130 SERINE PROTEASE INHIBITOR, SERPIN SERPIN 85F regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0053477|UniProtKB=A1Z885 A1Z885 Dmel\CG33477 PTHR20898:SF1 DAEDALUS ON 3-RELATED-RELATED MD-2-RELATED LIPID-RECOGNITION DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0038151|UniProtKB=Q9VFV2 Q9VFV2 yellow-e2 PTHR10009:SF7 PROTEIN YELLOW-RELATED GH10609P-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0027280|UniProtKB=Q9W3M4 Q9W3M4 orion PTHR47890:SF1 LD24308P LD24308P DROME|FlyBase=FBgn0042106|UniProtKB=Q9I7I1 Q9I7I1 Dmel\CG18754 PTHR24260:SF144 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED Toll pathway-drosophila#P06217>SPE#P06340 DROME|FlyBase=FBgn0013675|UniProtKB=P00408 P00408 mt:CoII PTHR22888:SF9 CYTOCHROME C OXIDASE, SUBUNIT II CYTOCHROME C OXIDASE SUBUNIT 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 organelle membrane#GO:0031090;transporter complex#GO:1990351;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 oxidoreductase#PC00176 Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06899;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06686;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#P06734 DROME|FlyBase=FBgn0002945|UniProtKB=Q9VVV9 Q9VVV9 nkd PTHR22611:SF9 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE Wnt signaling pathway#P00057>Naked#P01427 DROME|FlyBase=FBgn0028947|UniProtKB=Q9V402 Q9V402 BACR44L22.4 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0033571|UniProtKB=Q7JZF5 Q7JZF5 Polr2E PTHR10535:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase I#GO:0006360;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 DROME|FlyBase=FBgn0039341|UniProtKB=Q9VBQ5 Q9VBQ5 Dmel\CG5112 PTHR43372:SF1 FATTY-ACID AMIDE HYDROLASE LD38433P metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0029976|UniProtKB=Q9W3N0 Q9W3N0 snz PTHR22775:SF52 SORTING NEXIN FI21262P1 anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051076|UniProtKB=Q8IMQ4 Q8IMQ4 Dmel\CG31076 PTHR46282:SF2 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0003346|UniProtKB=Q9VIW3 Q9VIW3 RanGAP PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme binding#GO:0019899;binding#GO:0005488;molecular function activator activity#GO:0140677;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913;intracellular transport#GO:0046907;nuclear export#GO:0051168;nuclear transport#GO:0051169;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0029688|UniProtKB=Q8MSS1 Q8MSS1 lva PTHR45615:SF36 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN-LIKE, ISOFORM B-RELATED polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0000499|UniProtKB=P51140 P51140 dsh PTHR10878:SF25 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447 DROME|FlyBase=FBgn0052536|UniProtKB=Q9VWJ3 Q9VWJ3 Dmel\CG32536 PTHR15208:SF2 RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS CANCER ASSOCIATED SURFACE ANTIGEN RCAS1 ESTROGEN RECEPTOR-BINDING FRAGMENT- ASSOCIATED GENE 9 PROTEIN RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of secretion#GO:0051046;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0036873|UniProtKB=Q9VVZ7 Q9VVZ7 Dmel\CG18294 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0039625|UniProtKB=Q9VAQ8 Q9VAQ8 beta4GalNAcTB PTHR19300:SF48 BETA-1,4-GALACTOSYLTRANSFERASE BETA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE B hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194 primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0033457|UniProtKB=Q6NN40 Q6NN40 Ntmt PTHR12753:SF6 AD-003 - RELATED ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1 protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155;transferase#PC00220 DROME|FlyBase=FBgn0262743|UniProtKB=O18388 O18388 Fs(2)Ket PTHR10527:SF1 IMPORTIN BETA IMPORTIN SUBUNIT BETA-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;protein localization to organelle#GO:0033365;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0011294|UniProtKB=P54185 P54185 a5 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 DROME|FlyBase=FBgn0033673|UniProtKB=Q7JY99 Q7JY99 Dmel\CG8298 PTHR10196:SF99 SUGAR KINASE GLYCEROL KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;neutral lipid metabolic process#GO:0006638;carbohydrate derivative biosynthetic process#GO:1901137;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;alcohol metabolic process#GO:0006066;carbohydrate metabolic process#GO:0005975;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137;carbohydrate kinase#PC00065 DROME|FlyBase=FBgn0035236|UniProtKB=A1A714 A1A714 Tmep PTHR23423:SF17 ORGANIC SOLUTE TRANSPORTER-RELATED IP17403P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0263041|UniProtKB=A0A0B4K7A9 A0A0B4K7A9 CG5302 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0022724|UniProtKB=Q9VWY6 Q9VWY6 Taf8 PTHR46469:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 General transcription by RNA polymerase I#P00022>TAF-IB#P00650;General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>TAF-IC#P00649;General transcription regulation#P00023>TBP-associated factors#P00658;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 DROME|FlyBase=FBgn0031261|UniProtKB=Q9VPQ8 Q9VPQ8 nAChRbeta3 PTHR18945:SF824 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR BETA 3 (DBETA3) SUBUNIT monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231 trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 DROME|FlyBase=FBgn0033089|UniProtKB=Q4V5H1 Q4V5H1 Dmel\CG17266 PTHR11071:SF602 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0051826|UniProtKB=Q9VJN4 Q9VJN4 CG13241 PTHR10174:SF235 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0025391|UniProtKB=O76892 O76892 Scgdelta PTHR12939:SF11 SARCOGLYCAN EG:4F1.1 PROTEIN circulatory system process#GO:0003013;heart process#GO:0003015;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;system process#GO:0003008;heart contraction#GO:0060047 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0287873|UniProtKB=Q99323 Q99323 zip PTHR45615:SF40 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN, NON-MUSCLE catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 DROME|FlyBase=FBgn0036853|UniProtKB=Q9VVX4 Q9VVX4 mRpL21 PTHR21349:SF0 50S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 Methylcitrate cycle#P02754>Aconitase#P03028 DROME|FlyBase=FBgn0013343|UniProtKB=Q24547 Q24547 Syx1A PTHR19957:SF307 SYNTAXIN SYNTAXIN-1A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;exocytosis#GO:0006887;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031 intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;plasma membrane#GO:0005886;cytoplasm#GO:0005737 SNARE protein#PC00034 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066 DROME|FlyBase=FBgn0266720|UniProtKB=Q9VH76 Q9VH76 Snap24 PTHR19305:SF14 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN-RELATED binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484 exocytic process#GO:0140029;regulated exocytosis#GO:0045055;vesicle fusion to plasma membrane#GO:0099500;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;export from cell#GO:0140352;signaling#GO:0023052;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;synaptic vesicle membrane organization#GO:0048499;membrane fusion#GO:0061025;neurotransmitter secretion#GO:0007269;membrane organization#GO:0061024;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 SNARE protein#PC00034;membrane traffic protein#PC00150 Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Synaptic vesicle trafficking#P05734>SNAP-25#P05778;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049 DROME|FlyBase=FBgn0031470|UniProtKB=Q9VQH8 Q9VQH8 c-SPH125 PTHR24256:SF462 TRYPTASE-RELATED LP21446P-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0085426|UniProtKB=A0A076NAB7 A0A076NAB7 Rgk3 PTHR45775:SF1 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C RAD, GEM_KIR FAMILY MEMBER 3, ISOFORM E GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;calcium channel regulator activity#GO:0005246;ribonucleotide binding#GO:0032553;channel regulator activity#GO:0016247;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;ion channel regulator activity#GO:0099106 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0031998|UniProtKB=Q9VLR8 Q9VLR8 SLC5A11 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 sodium ion transport#GO:0006814;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0029941|UniProtKB=Q9W3R9 Q9W3R9 Dmel\CG1677 PTHR46582:SF1 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 DROME|FlyBase=FBgn0033750|UniProtKB=A1Z917 A1Z917 Dmel\CG13151 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 DROME|FlyBase=FBgn0022987|UniProtKB=A0A0B4KFT9 A0A0B4KFT9 qkr54B PTHR11208:SF157 RNA-BINDING PROTEIN RELATED QUAKING RELATED 54B, ISOFORM E RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0050493|UniProtKB=Q8MKN0 Q8MKN0 Coq9 PTHR21427:SF19 UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL lipid binding#GO:0008289;binding#GO:0005488 ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0261683|UniProtKB=M9MRD5 M9MRD5 B9d2 PTHR12968:SF2 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 2 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227 structural protein#PC00211 DROME|FlyBase=FBgn0036827|UniProtKB=Q9VVU4 Q9VVU4 Dmel\CG6843 PTHR13151:SF2 CBF1 INTERACTING COREPRESSOR CIR COREPRESSOR OF RBPJ AND SPLICING REGULATOR transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Notch signaling pathway#P00045>CoR#P01112 DROME|FlyBase=FBgn0045843|UniProtKB=P40809 P40809 RacGAP84C PTHR46199:SF3 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;signaling#GO:0023052;nuclear division#GO:0000280;cytokinesis#GO:0000910;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component assembly#GO:0022607;intracellular signaling cassette#GO:0141124;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cell division#GO:0051301;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;organelle assembly#GO:0070925;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;spindle organization#GO:0007051;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047 cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;cleavage furrow#GO:0032154;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membrane-bounded organelle#GO:0043227;midbody#GO:0030496;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GTPase-activating protein#PC00257;G-protein modulator#PC00022 DROME|FlyBase=FBgn0038134|UniProtKB=Q9VFX1 Q9VFX1 wntD PTHR12027:SF81 WNT RELATED WNT INHIBITOR OF DORSAL PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 DROME|FlyBase=FBgn0283651|UniProtKB=A0A1W5PXH3 A0A1W5PXH3 CG17341 PTHR12449:SF22 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4-LIKE ISOFORM X1 DROME|FlyBase=FBgn0028863|UniProtKB=X2J9Z3 X2J9Z3 stol PTHR10166:SF37 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED STOLID, ISOFORM H metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0038695|UniProtKB=Q9VDY3 Q9VDY3 Dmel\CG14280 PTHR33236:SF13 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0033507|UniProtKB=Q7K0D3 Q7K0D3 Dmel\CG12909 PTHR13100:SF10 CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR CELL GROWTH-REGULATING NUCLEOLAR PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA processing factor#PC00147 DROME|FlyBase=FBgn0031468|UniProtKB=Q9VQH6 Q9VQH6 Dmel\CG2975 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 transferase#PC00220 DROME|FlyBase=FBgn0284221|UniProtKB=Q9VTT0 Q9VTT0 Sema5c PTHR11036:SF79 SEMAPHORIN SEMAPHORIN 5C receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 DROME|FlyBase=FBgn0034898|UniProtKB=Q9W1K6 Q9W1K6 Dmel\CG18128 PTHR11904:SF9 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE-RELATED glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137 Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250 DROME|FlyBase=FBgn0051158|UniProtKB=E1JIT7 E1JIT7 Efa6 PTHR10663:SF376 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253 guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0052113|UniProtKB=Q9VU08 Q9VU08 Vps13D PTHR16166:SF141 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13D phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 mitochondrion organization#GO:0007005;membrane organization#GO:0061024;macroautophagy#GO:0016236;lipid transport#GO:0006869;autophagy#GO:0006914;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;transport#GO:0006810;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;lipid localization#GO:0010876 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;vesicle#GO:0031982 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0033136|UniProtKB=Q7JZW7 Q7JZW7 Tsp42Eo PTHR19282:SF566 TETRASPANIN RE08073P cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0037262|UniProtKB=Q8IH24 Q8IH24 MED31 PTHR13186:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0027581|UniProtKB=A0A0B4KF19 A0A0B4KF19 Cables1 PTHR22896:SF0 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0262869|UniProtKB=A0A0B4K7J4 A0A0B4K7J4 Gfrl PTHR10269:SF12 GDNF RECEPTOR ALPHA GLIAL CELL LINE-DERIVED NEUROTROPHIC FAMILY RECEPTOR-LIKE, ISOFORM E molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;system development#GO:0048731;nervous system development#GO:0007399 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0034628|UniProtKB=Q9W2G9 Q9W2G9 Acox57D-p PTHR10909:SF250 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE-RELATED oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;lipid binding#GO:0008289;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;organic acid binding#GO:0043177 cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0001990|UniProtKB=Q9VJN5 Q9VJN5 wek PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0035617|UniProtKB=Q9VRM6 Q9VRM6 l(3)psg2 PTHR23202:SF131 WASP INTERACTING PROTEIN-RELATED LETHAL (3) PERSISTENT SALIVARY GLAND 2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0052301|UniProtKB=Q9W037 Q9W037 CG8970 PTHR45627:SF12 ADENYLATE CYCLASE TYPE 1 ADENYLYL CYCLASE X E-RELATED adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0260634|UniProtKB=Q9VCH1 Q9VCH1 eIF4G2 PTHR23253:SF78 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;translation factor activity#GO:0180051 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 DROME|FlyBase=FBgn0031909|UniProtKB=Q9VM17 Q9VM17 CG5181 PTHR13356:SF0 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;response to radiation#GO:0009314;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;response to abiotic stimulus#GO:0009628;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0036605|UniProtKB=Q9VV29 Q9VV29 BcDNA:RE63063 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0052121|UniProtKB=Q8IQJ5 Q8IQJ5 tono PTHR23110:SF115 BTB DOMAIN TRANSCRIPTION FACTOR BTB DOMAIN-CONTAINING PROTEIN regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0031716|UniProtKB=Q9VMQ2 Q9VMQ2 Dmel\CG14015 PTHR13572:SF4 ENDO-ALPHA-1,2-MANNOSIDASE RE57134P catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 DROME|FlyBase=FBgn0000228|UniProtKB=P11929 P11929 Nin PTHR18905:SF13 NINEIN NINEIN HOMOLOG cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule anchoring#GO:0034453 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0262169|UniProtKB=Q0E9E0 Q0E9E0 magu PTHR12352:SF30 SECRETED MODULAR CALCIUM-BINDING PROTEIN FI05255P carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;heparin binding#GO:0008201;extracellular matrix binding#GO:0050840 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 calmodulin-related#PC00061 DROME|FlyBase=FBgn0037814|UniProtKB=Q9VGZ4 Q9VGZ4 Dmel\CG6325 PTHR28541:SF1 DDB1- AND CUL4-ASSOCIATED FACTOR 15 DDB1- AND CUL4-ASSOCIATED FACTOR 15 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0263051|UniProtKB=M9NEW0 M9NEW0 Dmel\CG43346 PTHR32470:SF2 ADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 chaperone#PC00072 DROME|FlyBase=FBgn0036771|UniProtKB=Q9VVM7 Q9VVM7 Wdr92 PTHR10971:SF2 MRNA EXPORT FACTOR AND BUB3 DYNEIN AXONEMAL ASSEMBLY FACTOR 10 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0040623|UniProtKB=Q9VAL0 Q9VAL0 Spase12 PTHR13202:SF0 MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 1 establishment of protein localization#GO:0045184;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;establishment of protein localization to endoplasmic reticulum#GO:0072599;metabolic process#GO:0008152;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;primary metabolic process#GO:0044238;protein targeting#GO:0006605;localization#GO:0051179;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 Vasopressin synthesis#P04395>Signal Peptidase#P04589 DROME|FlyBase=FBgn0036568|UniProtKB=Q8T4C4 Q8T4C4 ATPsynbetaL PTHR15184:SF88 ATP SYNTHASE ATP SYNTHASE F(1) COMPLEX SUBUNIT BETA, MITOCHONDRIAL passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020 ATP synthase#PC00002 ATP synthesis#P02721>F1 beta#P02794 DROME|FlyBase=FBgn0036557|UniProtKB=Q9VUX1 Q9VUX1 mRpS31 PTHR13231:SF3 MITOCHONDRIAL RIBOSOMAL PROTEIN S31 SMALL RIBOSOMAL SUBUNIT PROTEIN MS31 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0263697|UniProtKB=Q9V6U8 Q9V6U8 Uba3 PTHR10953:SF6 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;post-translational protein modification#GO:0043687 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 DROME|FlyBase=FBgn0031094|UniProtKB=Q9W5W6 Q9W5W6 Dmel\CG9578 PTHR21021:SF16 GAF/PUTATIVE CYTOSKELETAL PROTEIN TIP41-LIKE PROTEIN oxidoreductase activity#GO:0016491;phosphatase regulator activity#GO:0019208;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function activator activity#GO:0140677;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0029174|UniProtKB=Q9VL78 Q9VL78 Fkbp59 PTHR10516:SF443 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FK506-BINDING PROTEIN 59 catalytic activity#GO:0003824;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 DROME|FlyBase=FBgn0030224|UniProtKB=Q9W2S6 Q9W2S6 Dmel\CG12637 PTHR21644:SF0 AT02555P-RELATED AT02555P-RELATED DROME|FlyBase=FBgn0265298|UniProtKB=Q9V3T8 Q9V3T8 SC35 PTHR23147:SF22 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 2 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;nuclear speck#GO:0016607;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0032249|UniProtKB=Q9VKV6 Q9VKV6 TBC1D16 PTHR22957:SF547 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 16 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0035890|UniProtKB=Q9VSJ5 Q9VSJ5 Dmel\CG13667 PTHR19384:SF10 NITRIC OXIDE SYNTHASE-RELATED NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1 carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034247|UniProtKB=Q7K3P6 Q7K3P6 Dmel\CG6484 PTHR48021:SF102 FAMILY NOT NAMED GH07001P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0259713|UniProtKB=R9PY51 R9PY51 CG4588 PTHR12236:SF46 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 30B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033273|UniProtKB=Q7K5K0 Q7K5K0 Gasz PTHR24188:SF29 ANKYRIN REPEAT PROTEIN GH09064P DROME|FlyBase=FBgn0035922|UniProtKB=Q9VSN7 Q9VSN7 Pex7 PTHR46027:SF1 PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR signal sequence receptor activity#GO:0005048 protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;peroxisomal transport#GO:0043574;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;peroxisome organization#GO:0007031;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;microbody#GO:0042579;peroxisome#GO:0005777;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0010341|UniProtKB=P40793 P40793 Cdc42 PTHR24072:SF192 RHO FAMILY GTPASE CDC42 HOMOLOG carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;signaling#GO:0023052;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Integrin signalling pathway#P00034>Cdc42#P00938;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;Ras Pathway#P04393>Cdc42#P04569;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;p38 MAPK pathway#P05918>Cdc42#P06041;Axon guidance mediated by netrin#P00009>cdc42#P00364;FGF signaling pathway#P00021>Rac#P00645;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349 DROME|FlyBase=FBgn0015321|UniProtKB=P52486 P52486 Ubc4 PTHR24068:SF147 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 K ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Ubiquitin proteasome pathway#P00060>E3#P01490 DROME|FlyBase=FBgn0038415|UniProtKB=Q9VEW8 Q9VEW8 Dmel\CG17929 PTHR23529:SF2 GH19118P-RELATED GH19118P-RELATED DROME|FlyBase=FBgn0035233|UniProtKB=Q9W0D7 Q9W0D7 Pex10 PTHR23350:SF0 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 10 peroxisome organization#GO:0007031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;peroxisomal transport#GO:0043574;protein transport#GO:0015031;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 chaperone#PC00072 DROME|FlyBase=FBgn0050163|UniProtKB=Q8MLN7 Q8MLN7 Cpr60D PTHR10380:SF228 CUTICLE PROTEIN CUTICULAR PROTEIN 11A-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0284247|UniProtKB=Q24292 Q24292 ds PTHR24026:SF142 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN-23 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 DROME|FlyBase=FBgn0031403|UniProtKB=A8DYT6 A8DYT6 Dmel\CG15387 PTHR13463:SF3 PROTEIN C10 PROTEIN C10 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;post-embryonic development#GO:0009791 DROME|FlyBase=FBgn0030370|UniProtKB=Q9VYQ3 Q9VYQ3 Uch-L5R PTHR10589:SF51 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of chromosome organization#GO:0033044;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030944|UniProtKB=Q9VWS1 Q9VWS1 Hou PTHR12864:SF85 RAN BINDING PROTEIN 9-RELATED GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;proteasomal protein catabolic process#GO:0010498;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039147|UniProtKB=Q9VCD5 Q9VCD5 Dmel\CG10694 PTHR10621:SF0 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ubiquitin binding#GO:0043130;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0261258|UniProtKB=M9PFV8 M9PFV8 rgn PTHR23211:SF0 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN TGN38 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN 2 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0038345|UniProtKB=Q9VF55 Q9VF55 maca PTHR23147:SF22 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 2 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0037469|UniProtKB=Q9VI57 Q9VI57 Dpck PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED DEPHOSPHO-COA KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 kinase#PC00137;metabolite interconversion enzyme#PC00262 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 DROME|FlyBase=FBgn0043043|UniProtKB=Q9VG68 Q9VG68 Desat2 PTHR11351:SF104 ACYL-COA DESATURASE DESATURASE 1, ISOFORM A-RELATED oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 DROME|FlyBase=FBgn0036225|UniProtKB=Q9VTR0 Q9VTR0 Dmel\CG5883 PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0035321|UniProtKB=Q9I7U1 Q9I7U1 Dmel\CG1275 PTHR10106:SF0 CYTOCHROME B561-RELATED LD36721P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0026403|UniProtKB=A1Z877 A1Z877 Ndg PTHR13802:SF52 MUCIN 4-RELATED NIDOGEN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0039312|UniProtKB=Q9VBT6 Q9VBT6 Dmel\CG10514 PTHR11012:SF13 PROTEIN KINASE-LIKE DOMAIN-CONTAINING AT27361P-RELATED DROME|FlyBase=FBgn0262527|UniProtKB=E2QD16 E2QD16 nsl1 PTHR22443:SF18 NON-SPECIFIC LETHAL 1, ISOFORM M NON-SPECIFIC LETHAL 1, ISOFORM M protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234 DROME|FlyBase=FBgn0032715|UniProtKB=Q9VJ44 Q9VJ44 Dmel\CG17597 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED STEROL CARRIER PROTEIN 2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0003514|UniProtKB=P40423 P40423 sqh PTHR23049:SF72 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN SQH protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;post-embryonic development#GO:0009791;developmental process#GO:0032502 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0025790|UniProtKB=Q8SXP8 Q8SXP8 TBPH PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035677|UniProtKB=M9PER3 M9PER3 Dmel\CG13293 PTHR21243:SF21 PROTEIN SCAI PROTEIN SCAI transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0010038|UniProtKB=Q9VG98 Q9VG98 GstD2 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0031092|UniProtKB=Q9W5W8 Q9W5W8 Dmel\CG9577 PTHR43149:SF7 ENOYL-COA HYDRATASE DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydratase#PC00120 DROME|FlyBase=FBgn0037690|UniProtKB=Q9VHE0 Q9VHE0 Task7 PTHR11003:SF360 POTASSIUM CHANNEL, SUBFAMILY K IP11374P transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 cellular process#GO:0009987;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0261387|UniProtKB=Q7PLI7 Q7PLI7 CG17528 PTHR24349:SF243 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>CaMKIV#P07198 DROME|FlyBase=FBgn0032006|UniProtKB=E1JHB7 E1JHB7 Pvr PTHR24416:SF645 TYROSINE-PROTEIN KINASE RECEPTOR PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0262730|UniProtKB=X2JEB0 X2JEB0 dtn PTHR13388:SF11 DETONATOR, ISOFORM E DETONATOR, ISOFORM E membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030796|UniProtKB=Q7KUX2 Q7KUX2 Dmel\CG4829 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0085458|UniProtKB=A8JNS3 A8JNS3 Dmel\CG34429 PTHR21398:SF21 AGAP007094-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0036931|UniProtKB=Q9VW72 Q9VW72 Dmel\CG14183 PTHR14690:SF9 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 GH08353P DROME|FlyBase=FBgn0034816|UniProtKB=Q9W1V2 Q9W1V2 Dmel\CG3085 PTHR19960:SF7 TEKTIN TEKTIN cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;organelle assembly#GO:0070925;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0033277|UniProtKB=A1Z7C5 A1Z7C5 Dmel\CG14760 PTHR24258:SF134 SERINE PROTEASE-RELATED SUBFAMILY NOT NAMED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0028695|UniProtKB=Q9VW54 Q9VW54 Rpn1 PTHR10943:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;endopeptidase complex#GO:1905369 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0034590|UniProtKB=Q9W2L2 Q9W2L2 Magi PTHR10316:SF40 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED LD27118P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 DROME|FlyBase=FBgn0039797|UniProtKB=Q9VA45 Q9VA45 eIF4H2 PTHR23236:SF120 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4H RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0033737|UniProtKB=Q9V6B9 Q9V6B9 Nup54 PTHR13000:SF0 NUCLEOPORIN P54 NUCLEOPORIN P54 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;organelle organization#GO:0006996;macromolecule localization#GO:0033036;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear pore organization#GO:0006999;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;nucleocytoplasmic transport#GO:0006913;localization within membrane#GO:0051668 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 transporter#PC00227 DROME|FlyBase=FBgn0039199|UniProtKB=Q9VC76 Q9VC76 Dmel\CG13615 PTHR21253:SF0 F-BOX ONLY PROTEIN 11-RELATED F-BOX ONLY PROTEIN 11-RELATED DROME|FlyBase=FBgn0037249|UniProtKB=Q9VN25 Q9VN25 eIF3a PTHR14005:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;cytoplasmic translational initiation#GO:0002183;translation#GO:0006412;translational initiation#GO:0006413;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;cytosol#GO:0005829 translation initiation factor#PC00224 DROME|FlyBase=FBgn0037853|UniProtKB=Q9VGU7 Q9VGU7 Dmel\CG14696 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0019985|UniProtKB=P91685 P91685 mGluR PTHR24060:SF162 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 DROME|FlyBase=FBgn0052243|UniProtKB=Q8MZ22 Q8MZ22 BcDNA:RE12890 PTHR21115:SF0 GH06117P-RELATED GH06117P-RELATED DROME|FlyBase=FBgn0031454|UniProtKB=Q9VQF8 Q9VQF8 HemK2 PTHR45875:SF1 METHYLTRANSFERASE N6AMT1 METHYLTRANSFERASE HEMK2 catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 DROME|FlyBase=FBgn0035295|UniProtKB=Q9I7U5 Q9I7U5 Cnb PTHR34439:SF1 CENTROBIN CENTROBIN microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;centriole replication#GO:0007099;cytokinetic process#GO:0032506;organelle assembly#GO:0070925;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic cytokinetic process#GO:1902410;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 DROME|FlyBase=FBgn0021979|UniProtKB=Q7K274 Q7K274 l(2)k09913 PTHR20908:SF1 LD15586P LD15586P DROME|FlyBase=FBgn0011747|UniProtKB=Q0KIE7 Q0KIE7 Ank PTHR24133:SF33 ANKYRIN DOMAIN-CONTAINING ANKYRIN-3 ISOFORM X1 transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal adaptor activity#GO:0008093;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090 protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031157|UniProtKB=Q9VRE9 Q9VRE9 Dmel\CG1503 PTHR46468:SF1 SENTRIN-SPECIFIC PROTEASE 8 SENTRIN-SPECIFIC PROTEASE 8 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 protease#PC00190 DROME|FlyBase=FBgn0037431|UniProtKB=Q9I7L3 Q9I7L3 Dmel\CG17917 PTHR11362:SF44 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 DROME|FlyBase=FBgn0037230|UniProtKB=Q9VN01 Q9VN01 Nepl11 PTHR11733:SF251 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED GH23891P catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0001216|UniProtKB=P29843 P29843 Hsc70-1 PTHR19375:SF582 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 metabolic process#GO:0008152;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 DROME|FlyBase=FBgn0001114|UniProtKB=P33438 P33438 Glt PTHR43142:SF12 CARBOXYLIC ESTER HYDROLASE CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN-RELATED hydrolase#PC00121 DROME|FlyBase=FBgn0039633|UniProtKB=A0A0B4KI51 A0A0B4KI51 Bicra PTHR15572:SF0 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4 INTERACTING CHROMATIN REMODELING COMPLEX ASSOCIATED PROTEIN, ISOFORM B regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0036141|UniProtKB=Q95ST2 Q95ST2 wls PTHR13449:SF2 INTEGRAL MEMBRANE PROTEIN GPR177 PROTEIN WNTLESS HOMOLOG protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488 regulation of biological process#GO:0050789;protein localization to extracellular region#GO:0071692;signaling#GO:0023052;export from cell#GO:0140352;signal release#GO:0023061;localization#GO:0051179;protein secretion#GO:0009306;cell communication#GO:0007154;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020 DROME|FlyBase=FBgn0037571|UniProtKB=Q9VHT0 Q9VHT0 Dmel\CG11694 PTHR37161:SF2 HDC10475 AT11648P-RELATED DROME|FlyBase=FBgn0022700|UniProtKB=Q9W2M6 Q9W2M6 Cht4 PTHR11177:SF416 CHITINASE CHITINASE 9-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 DROME|FlyBase=FBgn0027073|UniProtKB=Q9W2J4 Q9W2J4 Ugt49B1 PTHR48043:SF60 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0020765|UniProtKB=P91941 P91941 Acp65Aa PTHR10380:SF248 CUTICLE PROTEIN ADULT CUTICLE PROTEIN 65AA extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0001311|UniProtKB=Q8IPN4 Q8IPN4 kkv PTHR22914:SF42 CHITIN SYNTHASE CHITIN SYNTHASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;biosynthetic process#GO:0009058;amino sugar metabolic process#GO:0006040;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;aminoglycan biosynthetic process#GO:0006023 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 transferase#PC00220 DROME|FlyBase=FBgn0014029|UniProtKB=P54359 P54359 Septin2 PTHR18884:SF69 SEPTIN SEPTIN-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0031450|UniProtKB=Q960X8 Q960X8 Hrs PTHR46275:SF1 HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;receptor internalization#GO:0031623;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;endocytosis#GO:0006897;endocytic recycling#GO:0032456 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 DROME|FlyBase=FBgn0036302|UniProtKB=B7Z0B0 B7Z0B0 sowah PTHR14491:SF7 SOSONDOWAH, ISOFORM G SOSONDOWAH, ISOFORM G DROME|FlyBase=FBgn0022023|UniProtKB=Q9U9Q4 Q9U9Q4 eIF3h PTHR10410:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;translation initiation factor activity#GO:0003743;peptidase activity#GO:0008233;catalytic activity#GO:0003824;translation factor activity#GO:0180051 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152 eukaryotic translation initiation factor 3 complex#GO:0005852;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0085290|UniProtKB=A8JNW5 A8JNW5 Targ3 PTHR12521:SF0 PROTEIN C6ORF130 ADP-RIBOSE GLYCOHYDROLASE OARD1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine nucleoside metabolic process#GO:0042278;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0033906|UniProtKB=A1Z9M2 A1Z9M2 ReepB PTHR12300:SF161 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN membrane traffic protein#PC00150 DROME|FlyBase=FBgn0037215|UniProtKB=Q9VMY5 Q9VMY5 beta-Man PTHR43730:SF1 BETA-MANNOSIDASE BETA-MANNOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycoprotein metabolic process#GO:0009100;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032638|UniProtKB=Q9VJD7 Q9VJD7 SPH93 PTHR24256:SF462 TRYPTASE-RELATED LP21446P-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0038009|UniProtKB=Q9VGB1 Q9VGB1 Dmel\CG17738 PTHR37372:SF1 OS06G0316800 PROTEIN GEO07177P1 DROME|FlyBase=FBgn0026438|UniProtKB=E1JHQ6 E1JHQ6 Eaat2 PTHR11958:SF111 SODIUM/DICARBOXYLATE SYMPORTER-RELATED AMINO ACID TRANSPORTER symporter activity#GO:0015293;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;acidic amino acid transmembrane transporter activity#GO:0015172 carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;establishment of localization#GO:0051234;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;L-glutamate import#GO:0051938;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 DROME|FlyBase=FBgn0003218|UniProtKB=P43125 P43125 rdgB PTHR10658:SF81 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PROTEIN RETINAL DEGENERATION B lipid binding#GO:0008289;lipid transfer activity#GO:0120013;binding#GO:0005488;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylcholine intramembrane carrier activity#GO:0008525;lipid carrier activity#GO:0005319;ion binding#GO:0043167;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transporter#PC00227 DROME|FlyBase=FBgn0052137|UniProtKB=Q8SWR2 Q8SWR2 BicDR PTHR32123:SF13 BICD FAMILY-LIKE CARGO ADAPTER BICAUDAL D-RELATED PROTEIN HOMOLOG membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0031992|UniProtKB=Q9VLS4 Q9VLS4 Acbp1 PTHR23310:SF51 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 7 heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0034403|UniProtKB=A1ZBF1 A1ZBF1 EB-SUN PTHR10623:SF6 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER EB1, ISOFORM F-RELATED microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226 microtubule end#GO:1990752;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;supramolecular fiber#GO:0099512;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037280|UniProtKB=Q9I7P3 Q9I7P3 BBS5 PTHR21351:SF0 BARDET-BIEDL SYNDROME PROTEIN 5 BBSOME COMPLEX MEMBER BBS5 binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;BBSome#GO:0034464;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 DROME|FlyBase=FBgn0261456|UniProtKB=Q8T0S6 Q8T0S6 hpo PTHR48015:SF33 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE HIPPO phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;hippo signaling#GO:0035329;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032428|UniProtKB=Q9VK91 Q9VK91 Fam92 PTHR21223:SF2 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0038006|UniProtKB=Q9VGB4 Q9VGB4 Cyp313a2 PTHR24305:SF224 CYTOCHROME P450 CYTOCHROME P450 313A1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036226|UniProtKB=Q9VTR1 Q9VTR1 BcDNA:LP01340 PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED carbohydrate derivative binding#GO:0097367;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0029891|UniProtKB=Q0KHV6 Q0KHV6 Pink1 PTHR22972:SF7 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PINK1, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;positive regulation of mitochondrial fission#GO:0090141;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;process utilizing autophagic mechanism#GO:0061919;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;positive regulation of developmental process#GO:0051094;regulation of apoptotic process#GO:0042981;regulation of anatomical structure morphogenesis#GO:0022603 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0261954|UniProtKB=O46048 O46048 east PTHR36562:SF6 SERINE/ARGININE REPETITIVE MATRIX 2 EG:133E12.4 PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0260932|UniProtKB=Q9V629 Q9V629 cuff PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN catalytic activity, acting on RNA#GO:0140098;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA catabolic process#GO:0006401;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036681|UniProtKB=Q7KUQ3 Q7KUQ3 Obp73a PTHR21066:SF18 ODORANT-BINDING PROTEIN 59A-RELATED ODORANT-BINDING PROTEIN 73A, ISOFORM B DROME|FlyBase=FBgn0000606|UniProtKB=P06602 P06602 eve PTHR46294:SF4 SEGMENTATION PROTEIN EVEN-SKIPPED SEGMENTATION PROTEIN EVEN-SKIPPED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0039207|UniProtKB=Q9VC63 Q9VC63 Cftr PTHR24223:SF479 ATP-BINDING CASSETTE SUB-FAMILY C CF TRANSMEMBRANE CONDUCTANCE REGULATOR, ISOFORM A localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0028518|UniProtKB=Q9VJN8 Q9VJN8 Dmel\CG18480 PTHR24366:SF168 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS GH22922P-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0032877|UniProtKB=Q9VIK5 Q9VIK5 Dmel\CG2617 PTHR22996:SF30 MAHOGUNIN RE60872P-RELATED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0031263|UniProtKB=Q9VPR1 Q9VPR1 Tspo PTHR10057:SF23 PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR TRANSLOCATOR PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 DROME|FlyBase=FBgn0054039|UniProtKB=A8E6W0 A8E6W0 CG34039-RA PTHR16231:SF4 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 4 DROME|FlyBase=FBgn0037515|UniProtKB=Q9V3Z2 Q9V3Z2 Sp7 PTHR24256:SF527 TRYPTASE-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 Toll pathway-drosophila#P06217>EA#P06339 DROME|FlyBase=FBgn0040208|UniProtKB=A0A0B4KFL3 A0A0B4KFL3 Kat60 PTHR23074:SF19 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A1 hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0030556|UniProtKB=Q9VY44 Q9VY44 mRNA-cap PTHR10367:SF17 MRNA-CAPPING ENZYME MRNA-CAPPING ENZYME catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 RNA processing factor#PC00147;mRNA capping factor#PC00145 DROME|FlyBase=FBgn0260856|UniProtKB=Q9VRL2 Q9VRL2 Membrin PTHR21230:SF1 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 2-RELATED molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150;SNARE protein#PC00034 DROME|FlyBase=FBgn0041713|UniProtKB=Q9VJQ3 Q9VJQ3 yellow-c PTHR10009:SF11 PROTEIN YELLOW-RELATED PROTEIN YELLOW cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0030499|UniProtKB=Q9VYB2 Q9VYB2 Dmel\CG11178 PTHR31017:SF1 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036437|UniProtKB=Q9VUG3 Q9VUG3 Dnaaf6 PTHR21083:SF0 TWISTER AT12351P binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;organelle assembly#GO:0070925;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0262871|UniProtKB=A0A0B4KGU2 A0A0B4KGU2 lute PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0051871|UniProtKB=Q9VKS5 Q9VKS5 CG17099 PTHR11005:SF144 LYSOSOMAL ACID LIPASE-RELATED AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 hydrolase#PC00121;lipase#PC00143 DROME|FlyBase=FBgn0038479|UniProtKB=Q9VEN0 Q9VEN0 Dmel\CG17477 PTHR24260:SF138 AT07769P-RELATED IP10340P-RELATED DROME|FlyBase=FBgn0036601|UniProtKB=Q9VV25 Q9VV25 Dmel\CG13063 PTHR34931:SF3 FI02976P-RELATED FI02976P-RELATED DROME|FlyBase=FBgn0037279|UniProtKB=Q7JZB4 Q7JZB4 Gmppb PTHR22572:SF15 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE CATALYTIC SUBUNIT BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 DROME|FlyBase=FBgn0027088|UniProtKB=Q9VUK8 Q9VUK8 GlyRS PTHR10745:SF0 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 GLYCINE--TRNA LIGASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0014141|UniProtKB=Q9VEN1 Q9VEN1 cher PTHR38537:SF17 JITTERBUG, ISOFORM N FILAMIN-A DROME|FlyBase=FBgn0036403|UniProtKB=Q95TY8 Q95TY8 PUT2 PTHR42862:SF1 DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;cytoplasmic side of plasma membrane#GO:0009898;mitochondrion#GO:0005739 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 DROME|FlyBase=FBgn0035917|UniProtKB=Q8IQB4 Q8IQB4 Zasp66 PTHR24214:SF55 PDZ AND LIM DOMAIN PROTEIN ZASP Z BAND ALTERNATIVELY SPLICED PDZ-MOTIF PROTEIN 66, ISOFORM E protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;actin filament-based process#GO:0030029;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;actomyosin#GO:0042641;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;stress fiber#GO:0001725;cytoskeleton#GO:0005856;actin filament#GO:0005884;I band#GO:0031674;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;sarcomere#GO:0030017;adherens junction#GO:0005912;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0039254|UniProtKB=Q9VC03 Q9VC03 Nmnat PTHR12039:SF0 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleotidyltransferase#PC00174;transferase#PC00220 DROME|FlyBase=FBgn0021872|UniProtKB=Q8MLW7 Q8MLW7 Xbp1 PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX-BINDING PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0033608|UniProtKB=Q6NP72 Q6NP72 Dmel\CG13220 PTHR38640:SF1 GEO09659P1 GEO09659P1 DROME|FlyBase=FBgn0031734|UniProtKB=Q9VMM9 Q9VMM9 Dmel\CG11147 PTHR43038:SF2 ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 RH61964P membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0010051|UniProtKB=P29993 P29993 Itpr PTHR13715:SF102 RYANODINE RECEPTOR AND IP3 RECEPTOR INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;phosphatidylinositol binding#GO:0035091;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;cation binding#GO:0043169;ligand-gated monoatomic ion channel activity#GO:0015276;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;metal ion binding#GO:0046872;gated channel activity#GO:0022836;calcium ion binding#GO:0005509;binding#GO:0005488 establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;signal transduction#GO:0007165;transmembrane transport#GO:0055085;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;secretory granule#GO:0030141;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ligand-gated ion channel#PC00141;ion channel#PC00133 PDGF signaling pathway#P00047>IP3 receptor#P01160;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>IP3R#P01064;Wnt signaling pathway#P00057>IP3 Gated Calcium Channel#P01426;Endothelin signaling pathway#P00019>IP3 R#P00590;Histamine H1 receptor mediated signaling pathway#P04385>IP3R#P04486;Metabotropic glutamate receptor group I pathway#P00041>IP3R#P01056 DROME|FlyBase=FBgn0038418|UniProtKB=Q9VEW6 Q9VEW6 pad PTHR24406:SF43 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED IP01015P C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0016013|UniProtKB=Q9VZI8 Q9VZI8 Faa PTHR43069:SF2 FUMARYLACETOACETASE FUMARYLACETOACETASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 DROME|FlyBase=FBgn0030999|UniProtKB=Q9VWK3 Q9VWK3 Mur18B PTHR23301:SF112 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;carbohydrate derivative binding#GO:0097367 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312 DROME|FlyBase=FBgn0286788|UniProtKB=O16810 O16810 Orc1 PTHR10763:SF23 CELL DIVISION CONTROL PROTEIN 6-RELATED ORIGIN RECOGNITION COMPLEX SUBUNIT 1 nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;binding#GO:0005488;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;nuclear origin of replication recognition complex#GO:0005664 replication origin binding protein#PC00199 DROME|FlyBase=FBgn0003067|UniProtKB=P20007 P20007 Pepck1 PTHR11561:SF0 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP] catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;lyase activity#GO:0016829;cation binding#GO:0043169 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;small molecule biosynthetic process#GO:0044283;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;response to glucose#GO:0009749;response to nutrient levels#GO:0031667;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;hexose biosynthetic process#GO:0019319;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glucose homeostasis#GO:0042593;glucose metabolic process#GO:0006006;chemical homeostasis#GO:0048878;cellular response to glucose stimulus#GO:0071333;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;response to chemical#GO:0042221;response to lipid#GO:0033993;gluconeogenesis#GO:0006094;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to stress#GO:0006950;response to carbohydrate#GO:0009743;intracellular glucose homeostasis#GO:0001678;response to oxygen-containing compound#GO:1901700;response to monosaccharide#GO:0034284;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;carbohydrate homeostasis#GO:0033500;response to hexose#GO:0009746;carboxylic acid metabolic process#GO:0019752 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 DROME|FlyBase=FBgn0031047|UniProtKB=Q7JVP2 Q7JVP2 Rcd-1 PTHR12262:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;CCR4-NOT complex#GO:0030014 DROME|FlyBase=FBgn0004863|UniProtKB=Q7KS72 Q7KS72 C15 PTHR45921:SF6 IP01054P C15 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0259749|UniProtKB=Q9Y0Z0 Q9Y0Z0 mmy PTHR11952:SF20 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLGLUCOSAMINE DIPHOSPHORYLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 DROME|FlyBase=FBgn0053096|UniProtKB=A0A4D6K2Q0 A0A4D6K2Q0 CG11935 PTHR12277:SF204 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PALMITOYL-PROTEIN HYDROLASE palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 serine protease#PC00203 DROME|FlyBase=FBgn0032188|UniProtKB=Q9VL33 Q9VL33 Dmel\CG13137 PTHR14494:SF0 ALADIN/ADRACALIN/AAAS ALADIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;microtubule bundle formation#GO:0001578;nuclear division#GO:0000280;organelle assembly#GO:0070925;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0037092|UniProtKB=M9PGC0 M9PGC0 M6 PTHR11683:SF12 MYELIN PROTEOLIPID M6, ISOFORM F multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 myelin protein#PC00161 DROME|FlyBase=FBgn0031894|UniProtKB=Q9VM37 Q9VM37 Dmel\CG4496 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0000071|UniProtKB=P15364 P15364 Ama PTHR42757:SF32 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED PROTEIN AMALGAM cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin#PC00123 DROME|FlyBase=FBgn0003093|UniProtKB=P13678 P13678 Pkc98E PTHR24356:SF240 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Apoptosis signaling pathway#P00006>PKCs#P00318;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Endothelin signaling pathway#P00019>PKC#P00568 DROME|FlyBase=FBgn0039010|UniProtKB=Q9VCV7 Q9VCV7 Dmel\CG4907 PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 extracellular matrix glycoprotein#PC00100 DROME|FlyBase=FBgn0039631|UniProtKB=Q9VAQ1 Q9VAQ1 Sirt7 PTHR11085:SF1 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7 acyltransferase activity#GO:0016746;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;deacylase activity#GO:0160215;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 response to stress#GO:0006950;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0003140|UniProtKB=P11612 P11612 PpY-55A PTHR11668:SF530 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Y-RELATED catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 DROME|FlyBase=FBgn0042641|UniProtKB=Q95YI5 Q95YI5 frc PTHR11132:SF558 SOLUTE CARRIER FAMILY 35 UDP-SUGAR TRANSPORTER UST74C carboxylic acid transmembrane transporter activity#GO:0046943;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0031568|UniProtKB=Q9VQU7 Q9VQU7 GH25970 PTHR11360:SF93 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 7-LIKE PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0259795|UniProtKB=Q7K2S9 Q7K2S9 loopin-1 PTHR11963:SF16 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0037743|UniProtKB=Q9VH78 Q9VH78 Alg12 PTHR22760:SF1 GLYCOSYLTRANSFERASE DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0043456|UniProtKB=Q8T079 Q8T079 Ndf PTHR43580:SF10 OXIDOREDUCTASE GLYR1-RELATED CYTOKINE-LIKE NUCLEAR FACTOR N-PAC DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682 cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176 DROME|FlyBase=FBgn0034269|UniProtKB=Q7K1C5 Q7K1C5 Hyccin PTHR31220:SF10 HYCCIN RELATED GH21176P localization within membrane#GO:0051668;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;localization#GO:0051179;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0032945|UniProtKB=Q9VIC9 Q9VIC9 Dmel\CG8665 PTHR11699:SF190 ALDEHYDE DEHYDROGENASE-RELATED 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 DROME|FlyBase=FBgn0259185|UniProtKB=B7YZQ4 B7YZQ4 Ir60b PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0041186|UniProtKB=Q9VAN6 Q9VAN6 Slbp PTHR17408:SF0 HISTONE RNA HAIRPIN-BINDING PROTEIN HISTONE RNA HAIRPIN-BINDING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA metabolic process#GO:0016071;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;nucleic acid biosynthetic process#GO:0141187;localization#GO:0051179;nucleic acid transport#GO:0050657;RNA metabolic process#GO:0016070;macromolecule localization#GO:0033036;mRNA processing#GO:0006397;nitrogen compound transport#GO:0071705;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transport#GO:0006810;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0040232|UniProtKB=Q9VKI0 Q9VKI0 cmet PTHR47968:SF80 CENTROMERE PROTEIN E CENP-ANA, ISOFORM A-RELATED protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;cell cycle#GO:0007049;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0032938|UniProtKB=Q9VID5 Q9VID5 Dmel\CG8671 PTHR21456:SF1 FAMILY WITH SEQUENCE SIMILARITY 102 C2 NT-TYPE DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0013764|UniProtKB=Q7KVG9 Q7KVG9 Chi PTHR10378:SF50 LIM DOMAIN-BINDING PROTEIN CHIP, ISOFORM B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0039089|UniProtKB=A0A0B4KGP4 A0A0B4KGP4 beat-IV PTHR21261:SF14 BEAT PROTEIN BEATEN PATH IV, ISOFORM B intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0001147|UniProtKB=P09083 P09083 gsb-n PTHR45636:SF55 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PROTEIN GOOSEBERRY-NEURO sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0034827|UniProtKB=Q9W1U1 Q9W1U1 Klp59D PTHR24115:SF0 KINESIN-RELATED FI21273P1-RELATED protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 microtubule-based movement#GO:0007018;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0040373|UniProtKB=Q95RP8 Q95RP8 EG:BACR37P7.1 PTHR11214:SF235 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0020371|UniProtKB=Q9VJP1 Q9VJP1 Tim17b2 PTHR10485:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 AT05822P-RELATED transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial transmembrane transport#GO:1990542;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 transporter#PC00227 DROME|FlyBase=FBgn0031006|UniProtKB=Q9VWJ6 Q9VWJ6 rictor PTHR13298:SF11 CYTOSOLIC REGULATOR PIANISSIMO RAPAMYCIN-INSENSITIVE COMPANION OF MTOR protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;TOR signaling#GO:0031929;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;TORC2 signaling#GO:0038203;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signaling#GO:0023056;cell communication#GO:0007154 protein-containing complex#GO:0032991;TOR complex#GO:0038201;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0030631|UniProtKB=Q9VXW2 Q9VXW2 Prp5 PTHR24031:SF25 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX46-RELATED mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 DROME|FlyBase=FBgn0003460|UniProtKB=Q27350 Q27350 so PTHR10390:SF61 HOMEOBOX PROTEIN SIX HOMEOBOX DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0286567|UniProtKB=Q8IRE3 Q8IRE3 gry PTHR14374:SF1 FOIE GRAS TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0036774|UniProtKB=Q9VVN2 Q9VVN2 mRpS26 PTHR21035:SF2 28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS26 membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0260658|UniProtKB=Q7KVX6 Q7KVX6 CG16828 PTHR45775:SF6 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C RAD, GEM_KIR FAMILY MEMBER 2, ISOFORM C DROME|FlyBase=FBgn0036816|UniProtKB=Q9VVT2 Q9VVT2 Indy PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED citrate transmembrane transporter activity#GO:0015137;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;succinate transmembrane transporter activity#GO:0015141 cellular process#GO:0009987;succinate transport#GO:0015744;dicarboxylic acid transport#GO:0006835;citrate transport#GO:0015746;carboxylic acid transport#GO:0046942;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;organic acid transport#GO:0015849;tricarboxylic acid transport#GO:0006842;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0037950|UniProtKB=Q9VGI0 Q9VGI0 HisCl1 PTHR18945:SF942 NEUROTRANSMITTER GATED ION CHANNEL HISTAMINE-GATED CHLORIDE CHANNEL SUBUNIT 1 ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0033791|UniProtKB=Q7JQT0 Q7JQT0 Drl-2 PTHR24416:SF531 TYROSINE-PROTEIN KINASE RECEPTOR DERAILED 2, ISOFORM B catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;axonogenesis#GO:0007409;neuron development#GO:0048666;positive regulation of signaling#GO:0023056;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0013342|UniProtKB=Q9W0C1 Q9W0C1 nSyb PTHR45701:SF21 SYNAPTOBREVIN FAMILY MEMBER NEURONAL SYNAPTOBREVIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;vesicle organization#GO:0016050;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;vesicle fusion#GO:0006906;membrane organization#GO:0061024;cellular component organization#GO:0016043;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150 Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986 DROME|FlyBase=FBgn0024245|UniProtKB=Q9V422 Q9V422 dnt PTHR24416:SF349 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE RYK transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0067102|UniProtKB=Q9W297 Q9W297 GlcT PTHR12726:SF0 CERAMIDE GLUCOSYLTRANSFERASE CERAMIDE GLUCOSYLTRANSFERASE UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 glycosphingolipid biosynthetic process#GO:0006688;ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 membrane#GO:0016020;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0034887|UniProtKB=Q9W1L8 Q9W1L8 St1 PTHR11783:SF180 SULFOTRANSFERASE SULT GH11818P-RELATED sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0036553|UniProtKB=Q9VUW4 Q9VUW4 IMP PTHR20854:SF25 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 DROME|FlyBase=FBgn0286781|UniProtKB=Q9V431 Q9V431 cass PTHR12758:SF25 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038306|UniProtKB=Q9VFB3 Q9VFB3 Art3 PTHR11006:SF125 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 3 histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036887|UniProtKB=Q9VW12 Q9VW12 CG9231 PTHR13674:SF5 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN UPF0389 PROTEIN CG9231 DROME|FlyBase=FBgn0010100|UniProtKB=Q9VIE8 Q9VIE8 mAcon1 PTHR43160:SF3 ACONITATE HYDRATASE B ACONITATE HYDRATASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488 tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 lyase#PC00144;hydratase#PC00120 TCA cycle#P00051>Aconitase#P01268 DROME|FlyBase=FBgn0032969|UniProtKB=Q9V9P5 Q9V9P5 lincRNA.224 PTHR42881:SF2 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protease#PC00190;serine protease#PC00203 Vasopressin synthesis#P04395>Endo Peptidase#P04596 DROME|FlyBase=FBgn0050503|UniProtKB=Q7JX94 Q7JX94 CG1672 PTHR12253:SF43 RH14732P PHOSPHOLIPASE A2 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787 DROME|FlyBase=FBgn0038787|UniProtKB=Q9VDN4 Q9VDN4 Sag1 PTHR24377:SF995 IP01015P-RELATED LD25464P-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0022213|UniProtKB=Q9XZU1 Q9XZU1 Cse1 PTHR10997:SF8 IMPORTIN-7, 8, 11 EXPORTIN-2 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transporter#PC00227 DROME|FlyBase=FBgn0263351|UniProtKB=O62530 O62530 AP-2mu PTHR10529:SF377 AP COMPLEX SUBUNIT MU ADAPTOR PROTEIN COMPLEX 2, MU SUBUNIT, ISOFORM A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;Golgi vesicle transport#GO:0048193;transport#GO:0006810 coated membrane#GO:0048475;coated vesicle#GO:0030135;endocytic vesicle#GO:0030139;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin vesicle coat#GO:0030125;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane coat#GO:0030117;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;plasma membrane#GO:0005886;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytosol#GO:0005829;vesicle membrane#GO:0012506;cell periphery#GO:0071944 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0036877|UniProtKB=Q9VW01 Q9VW01 Dmel\CG9452 PTHR11567:SF205 ACID PHOSPHATASE-RELATED GH28721P-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phosphatase#PC00181 DROME|FlyBase=FBgn0032901|UniProtKB=Q9VIH7 Q9VIH7 sky PTHR23354:SF122 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED GTPASE-ACTIVATING PROTEIN SKYWALKER DROME|FlyBase=FBgn0288232|UniProtKB=Q9V774 Q9V774 Cyp6a21 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0034493|UniProtKB=A1ZBS3 A1ZBS3 Dmel\CG8908 PTHR19229:SF278 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234;lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0032724|UniProtKB=Q9VJ34 Q9VJ34 CG10428 PTHR13369:SF0 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0031851|UniProtKB=Q9VM95 Q9VM95 Aatf PTHR15565:SF0 AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR PROTEIN AATF cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0020305|UniProtKB=Q9VPU8 Q9VPU8 dbe PTHR12581:SF0 HIV-1 REV BINDING PROTEIN 2, 3 KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035952|UniProtKB=Q9VSS7 Q9VSS7 CG5280 PTHR28348:SF1 UPF0193 PROTEIN EVG1 UPF0193 PROTEIN EVG1 DROME|FlyBase=FBgn0053286|UniProtKB=Q7KTX4 Q7KTX4 CG12982 PTHR20929:SF12 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED AT08232P binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;axoneme#GO:0005930;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226 DROME|FlyBase=FBgn0000427|UniProtKB=P18171 P18171 dec PTHR14596:SF76 ZINC FINGER PROTEIN DEFECTIVE CHORION PROTEIN, FC177 ISOFORM DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 response to stimulus#GO:0050896;response to stress#GO:0006950;response to nutrient levels#GO:0031667;response to starvation#GO:0042594 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0265935|UniProtKB=A0A0B4KEJ7 A0A0B4KEJ7 coro PTHR10856:SF0 CORONIN CORONIN binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0014366|UniProtKB=O46106 O46106 noi PTHR12786:SF2 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723 mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 spliceosomal complex#GO:0005681;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0032464|UniProtKB=Q9VK47 Q9VK47 Vha68-3 PTHR43607:SF10 V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A H(+)-TRANSPORTING TWO-SECTOR ATPASE monoatomic cation transmembrane transporter activity#GO:0008324;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic ion transport#GO:0006811;transport#GO:0006810 lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;cation-transporting ATPase complex#GO:0090533;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495 ATP synthase#PC00002 DROME|FlyBase=FBgn0025637|UniProtKB=O77430 O77430 SkpA PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003257|UniProtKB=Q01637 Q01637 r-l PTHR19278:SF9 OROTATE PHOSPHORIBOSYLTRANSFERASE URIDINE 5'-MONOPHOSPHATE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;pentosyltransferase activity#GO:0016763;lyase activity#GO:0016829;glycosyltransferase activity#GO:0016757 nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Orotate phosphoribosyltransferase#P02922 DROME|FlyBase=FBgn0287183|UniProtKB=Q7PLG1 Q7PLG1 l(3)80Fg PTHR44303:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;regulation of biological quality#GO:0065008;process utilizing autophagic mechanism#GO:0061919;organelle organization#GO:0006996;cellular component organization#GO:0016043;autophagy#GO:0006914;regulation of cellular component size#GO:0032535;autophagosome organization#GO:1905037;cellular process#GO:0009987;catabolic process#GO:0009056;biological regulation#GO:0065007;macroautophagy#GO:0016236 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 chaperone#PC00072 DROME|FlyBase=FBgn0035807|UniProtKB=Q9VS98 Q9VS98 Dmel\CG7492 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED DROME|FlyBase=FBgn0027528|UniProtKB=Q9XZ14 Q9XZ14 goe PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0011674|UniProtKB=Q9W2R4 Q9W2R4 insc PTHR21386:SF0 INSCUTEABLE PROTEIN INSCUTEABLE HOMOLOG cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;regulation of cell division#GO:0051302;macromolecule localization#GO:0033036;biological regulation#GO:0065007;intracellular protein localization#GO:0008104;regulation of cellular process#GO:0050794;localization#GO:0051179 cell cortex#GO:0005938;cell periphery#GO:0071944;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036273|UniProtKB=Q9VTW2 Q9VTW2 INPP5E PTHR47039:SF1 INOSITOL POLYPHOSPHATE 5-PHOSPHATASE E INOSITOL POLYPHOSPHATE 5-PHOSPHATASE E nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;localization#GO:0051179;system process#GO:0003008;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;protein localization to organelle#GO:0033365;sensory perception of sound#GO:0007605;protein localization to cilium#GO:0061512 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;ciliary base#GO:0097546;cilium#GO:0005929 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0024957|UniProtKB=Q9VGZ3 Q9VGZ3 Irp-1B PTHR11670:SF75 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER CYTOPLASMIC ACONITATE HYDRATASE hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824;iron-sulfur cluster binding#GO:0051536;RNA binding#GO:0003723;lyase activity#GO:0016829;small molecule binding#GO:0036094;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 DROME|FlyBase=FBgn0032393|UniProtKB=Q9VKD3 Q9VKD3 Nfs1 PTHR11601:SF65 CYSTEINE DESULFURYLASE FAMILY MEMBER CYSTEINE DESULFURASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;nucleus#GO:0005634 lyase#PC00144;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0002941|UniProtKB=P22807 P22807 slou PTHR24340:SF37 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN SLOU transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0024191|UniProtKB=Q9Y103 Q9Y103 sip1 PTHR23329:SF1 TUFTELIN-INTERACTING PROTEIN 11-RELATED TUFTELIN-INTERACTING PROTEIN 11 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;protein-containing complex disassembly#GO:0032984;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0031741|UniProtKB=Q9VMM2 Q9VMM2 Dmel\CG11034 PTHR11731:SF154 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED VENOM DIPEPTIDYL PEPTIDASE 4 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203 DROME|FlyBase=FBgn0034050|UniProtKB=Q7JXE1 Q7JXE1 bug PTHR14684:SF2 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 DROME|FlyBase=FBgn0039112|UniProtKB=Q9VCI5 Q9VCI5 SdhD PTHR13337:SF2 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;tricarboxylic acid cycle#GO:0006099;electron transport chain#GO:0022900;primary metabolic process#GO:0044238;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 catalytic complex#GO:1902494;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176 DROME|FlyBase=FBgn0000052|UniProtKB=P35421 P35421 Pfas PTHR10099:SF1 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 De novo purine biosynthesis#P02738>Phosphoribosylformylglycinamide synthase#P02898 DROME|FlyBase=FBgn0264815|UniProtKB=B7YZV4 B7YZV4 Pde1c PTHR11347:SF226 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 phosphodiesterase#PC00185;hydrolase#PC00121 DROME|FlyBase=FBgn0263599|UniProtKB=Q9VUV9 Q9VUV9 Brr2 PTHR24075:SF5 SEC63 DOMAIN-CONTAINING U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0032635|UniProtKB=Q9VJE3 Q9VJE3 Dmel\CG15141 PTHR13513:SF9 E3 UBIQUITIN-PROTEIN LIGASE UBR7 E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0037115|UniProtKB=Q9VNZ9 Q9VNZ9 Pykl5 PTHR11817:SF3 PYRUVATE KINASE AT14039P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;pyruvate kinase activity#GO:0004743 ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 DROME|FlyBase=FBgn0026433|UniProtKB=Q9VXU8 Q9VXU8 Grip128 PTHR19302:SF33 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 5 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0015795|UniProtKB=O76742 O76742 Rab7 PTHR47981:SF45 RAB FAMILY RAS-RELATED PROTEIN RAB7 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;phagolysosome assembly#GO:0001845;intracellular transport#GO:0046907;phagocytosis#GO:0006909;vacuolar transport#GO:0007034;lytic vacuole organization#GO:0080171;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle organization#GO:0016050;cellular component organization#GO:0016043;endocytosis#GO:0006897;vesicle fusion#GO:0006906;organelle assembly#GO:0070925;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033 vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;phagocytic vesicle#GO:0045335;lytic vacuole#GO:0000323;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 small GTPase#PC00208 DROME|FlyBase=FBgn0038750|UniProtKB=Q9VDS2 Q9VDS2 Dmel\CG4465 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0050000|UniProtKB=Q7K0B6 Q7K0B6 GstT1 PTHR43917:SF8 FAMILY NOT NAMED GH16740P-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 DROME|FlyBase=FBgn0000594|UniProtKB=P18167 P18167 Est-P PTHR11559:SF429 CARBOXYLESTERASE ESTERASE P-RELATED esterase#PC00097 DROME|FlyBase=FBgn0086532|UniProtKB=Q6NR46 Q6NR46 Spt-I PTHR13693:SF2 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transaminase#PC00216 DROME|FlyBase=FBgn0086368|UniProtKB=Q9W5D4 Q9W5D4 tw PTHR10050:SF46 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 2 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037429|UniProtKB=Q9VI06 Q9VI06 Osi19 PTHR21879:SF6 FI03362P-RELATED-RELATED OSIRIS 19, ISOFORM A membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0034718|UniProtKB=Q9W266 Q9W266 wdp PTHR24369:SF215 ANTIGEN BSP, PUTATIVE-RELATED PROTEIN WINDPIPE membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0030678|UniProtKB=Q9VXQ8 Q9VXQ8 Dmel\CG11679 PTHR16255:SF1 REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 DROME|FlyBase=FBgn0053557|UniProtKB=Q59E67 Q59E67 soul PTHR23349:SF42 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0036367|UniProtKB=Q9VU78 Q9VU78 Dmel\CG10116 PTHR11610:SF192 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0035648|UniProtKB=M9PEG2 M9PEG2 dmCG13288 PTHR36694:SF14 PASIFLORA 1, ISOFORM A-RELATED LP21121P DROME|FlyBase=FBgn0039858|UniProtKB=Q95TJ9 Q95TJ9 CycG PTHR10177:SF584 CYCLINS CYCLIN G cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 DROME|FlyBase=FBgn0051223|UniProtKB=Q7KSA2 Q7KSA2 Dmel\CG31223 PTHR15555:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2 DROME|FlyBase=FBgn0016034|UniProtKB=Q9VNS0 Q9VNS0 mael PTHR21358:SF4 PROTEIN MAELSTROM HOMOLOG PROTEIN MAELSTROM HOMOLOG transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;regulation of DNA-templated transcription#GO:0006355;organelle fission#GO:0048285;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;meiotic cell cycle process#GO:1903046;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;gamete generation#GO:0007276;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;nuclear division#GO:0000280;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;male meiotic nuclear division#GO:0007140;nucleobase-containing compound biosynthetic process#GO:0034654;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0025394|UniProtKB=Q9W579 Q9W579 inc PTHR14958:SF29 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN INSOMNIAC, ISOFORM B protein binding#GO:0005515;binding#GO:0005488 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033395|UniProtKB=Q9V557 Q9V557 Cyp4p2 PTHR24291:SF105 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4P1-RELATED oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0037454|UniProtKB=Q9VI32 Q9VI32 Dmel\CG1137 PTHR31598:SF1 IQ DOMAIN-CONTAINING PROTEIN D DYNEIN REGULATORY COMPLEX SUBUNIT 10 DROME|FlyBase=FBgn0051014|UniProtKB=Q9VA63 Q9VA63 PH4alphaSG1 PTHR10869:SF216 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROCOLLAGEN-PROLINE 4-DIOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 oxidoreductase complex#GO:1990204;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031446|UniProtKB=Q9VQE8 Q9VQE8 Trf5 PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;Huntington disease#P00029>TBP#P00779 DROME|FlyBase=FBgn0033486|UniProtKB=Q7K2J4 Q7K2J4 dmpd PTHR13252:SF1 F-BOX ONLY PROTEIN 28 DAMPENED, ISOFORM A transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0031654|UniProtKB=Q9VMX8 Q9VMX8 Jon25Bii PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0034585|UniProtKB=Q9W2M0 Q9W2M0 Rbpn-5 PTHR23164:SF30 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;endocytosis#GO:0006897;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0051064|UniProtKB=A0A0B4LHR8 A0A0B4LHR8 CG14261 PTHR45956:SF6 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0036790|UniProtKB=Q9VVQ1 Q9VVQ1 AstC-R1 PTHR24229:SF114 NEUROPEPTIDES RECEPTOR ALLATOSTATIN C RECEPTOR 1-RELATED binding#GO:0005488;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 DROME|FlyBase=FBgn0030408|UniProtKB=Q9VYL0 Q9VYL0 Dmel\CG11085 PTHR45921:SF4 IP01054P IP01054P DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0051660|UniProtKB=M9ND25 M9ND25 smog PTHR32546:SF26 G-PROTEIN COUPLED RECEPTOR 158-RELATED SMOG, ISOFORM D G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0000451|UniProtKB=X2JAX9 X2JAX9 ect PTHR35711:SF1 EXPRESSED PROTEIN ECTODERMAL, ISOFORM F DROME|FlyBase=FBgn0287186|UniProtKB=Q7PL95 Q7PL95 scro PTHR24340:SF41 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN CEH-24-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0035719|UniProtKB=M9PET2 M9PET2 tow PTHR14974:SF3 SIMILAR TO RIKEN CDNA 1700025G04 GENE SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 21 DROME|FlyBase=FBgn0005670|UniProtKB=P33269 P33269 Cyp4d1 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0265598|UniProtKB=M9PI02 M9PI02 Bx PTHR45787:SF1 LD11652P BEADEX, ISOFORM D transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0035268|UniProtKB=Q9W091 Q9W091 Dmel\CG8001 PTHR15574:SF21 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1 AND CUL4 ASSOCIATED FACTOR 8 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0033783|UniProtKB=A1Z971 A1Z971 dRNF34 PTHR14879:SF15 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RIFIFYLIN-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;regulation of extrinsic apoptotic signaling pathway#GO:2001236;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0001228|UniProtKB=P22978 P22978 CG4456 PTHR44086:SF15 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220 DROME|FlyBase=FBgn0085223|UniProtKB=A8DYH6 A8DYH6 Dmel\CG34194 PTHR28612:SF2 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032683|UniProtKB=Q9VJ82 Q9VJ82 kon PTHR15036:SF56 PIKACHURIN-LIKE PROTEIN KON-TIKI, ISOFORM B cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0026384|UniProtKB=P81923 P81923 Or59a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034223|UniProtKB=A1ZAT5 A1ZAT5 Tes PTHR24211:SF22 LIM DOMAIN-CONTAINING PROTEIN TESTIN scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0024806|UniProtKB=Q9W0S9 Q9W0S9 DIP2 PTHR22754:SF45 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0038947|UniProtKB=Q9VD29 Q9VD29 Sar1 PTHR45684:SF2 RE74312P SMALL MONOMERIC GTPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114 coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971 DROME|FlyBase=FBgn0034345|UniProtKB=A0A0B4K897 A0A0B4K897 BcDNA:RH27395 PTHR19307:SF14 TUMOR PROTEIN D52 TUMOR PROTEIN D52 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039404|UniProtKB=Q9VBI0 Q9VBI0 Dmel\CG14543 PTHR21250:SF0 PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0003132|UniProtKB=Q05547 Q05547 Pp1-13C PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE-RELATED phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 DROME|FlyBase=FBgn0037819|UniProtKB=Q9VGY8 Q9VGY8 Phyhd1 PTHR20883:SF15 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0003130|UniProtKB=P23758 P23758 Poxn PTHR45636:SF43 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX POX-NEURO PROTEIN-RELATED DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0259173|UniProtKB=Q8IQ73 Q8IQ73 corn PTHR34491:SF176 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED CORNETTO, ISOFORM C DROME|FlyBase=FBgn0014075|UniProtKB=Q09332 Q09332 Uggt PTHR11226:SF0 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0028945|UniProtKB=Q9V3R0 Q9V3R0 BG:BACR44L22.6 PTHR10127:SF914 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 DROME|FlyBase=FBgn0032338|UniProtKB=M9ND65 M9ND65 Dmel\CG16854 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED DROME|FlyBase=FBgn0039680|UniProtKB=Q9VAJ1 Q9VAJ1 Cap-D2 PTHR14222:SF2 CONDENSIN CONDENSIN COMPLEX SUBUNIT 1 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 nuclear division#GO:0000280;sexual reproduction#GO:0019953;organelle fission#GO:0048285;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;cell cycle#GO:0007049;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987 chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;condensin complex#GO:0000796;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0002413|UniProtKB=O76324 O76324 dco PTHR11909:SF428 CASEIN KINASE-RELATED DISCS OVERGROWN PROTEIN KINASE-RELATED catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of signal transduction#GO:0009967;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242 DROME|FlyBase=FBgn0028325|UniProtKB=Q7KVX1 Q7KVX1 Pdha1 PTHR11516:SF60 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyruvate metabolic process#GO:0006090 membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;dehydrogenase#PC00092 Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 DROME|FlyBase=FBgn0036870|UniProtKB=Q9VVZ4 Q9VVZ4 Dmel\CG14095 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0030976|UniProtKB=X2JEB8 X2JEB8 MKP-like PTHR45682:SF5 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 DROME|FlyBase=FBgn0026373|UniProtKB=O97183 O97183 Polr2C PTHR11800:SF2 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 DROME|FlyBase=FBgn0014189|UniProtKB=Q27268 Q27268 Hel25E PTHR47958:SF104 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE WM6 ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386 nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;localization#GO:0051179;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nuclear transport#GO:0051169;nuclear export#GO:0051168;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 RNA helicase#PC00032 DROME|FlyBase=FBgn0051493|UniProtKB=Q8INT0 Q8INT0 Dmel\CG31493 PTHR20905:SF28 N-ACETYLTRANSFERASE-RELATED GH28833P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acetyltransferase activity#GO:0008080 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0032507|UniProtKB=Q9VJZ8 Q9VJZ8 c-SPH166 PTHR24260:SF87 AT07769P-RELATED GH08193P-RELATED DROME|FlyBase=FBgn0034503|UniProtKB=A1ZBT5 A1ZBT5 MED8 PTHR13074:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 general transcription factor#PC00259 DROME|FlyBase=FBgn0050106|UniProtKB=A1ZAX0 A1ZAX0 CCHa1-R PTHR45695:SF26 LEUCOKININ RECEPTOR-RELATED NEUROPEPTIDE CCHAMIDE-1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0053307|UniProtKB=Q961T9 Q961T9 BG:DS00941.11 PTHR20993:SF0 GH07914P GH07914P DROME|FlyBase=FBgn0037019|UniProtKB=Q9VPB9 Q9VPB9 Pex16 PTHR13299:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX16 PEROXISOMAL MEMBRANE PROTEIN PEX16 cellular component organization or biogenesis#GO:0071840;peroxisome organization#GO:0007031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0053476|UniProtKB=A1Z886 A1Z886 Dmel\CG33476 PTHR20898:SF1 DAEDALUS ON 3-RELATED-RELATED MD-2-RELATED LIPID-RECOGNITION DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0263106|UniProtKB=Q24133 Q24133 DnaJ-1 PTHR24078:SF586 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 5 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0002948|UniProtKB=P18105 P18105 nod PTHR24115:SF1004 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF15 ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0046687|UniProtKB=Q9NDM2 Q9NDM2 Tre1 PTHR24228:SF71 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR PROTEIN TRAPPED IN ENDODERM-1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0028687|UniProtKB=Q7KMQ0 Q7KMQ0 Rpt1 PTHR23073:SF13 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 7 isomerase activity#GO:0016853;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0051721|UniProtKB=M9MRI4 M9MRI4 Trim9 PTHR24099:SF15 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM9 axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0038854|UniProtKB=Q9VDE8 Q9VDE8 Brat1 PTHR21331:SF2 BRCA1-ASSOCIATED ATM ACTIVATOR 1 INTEGRATOR COMPLEX ASSEMBLY FACTOR BRAT1 response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stress#GO:0006950 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0052547|UniProtKB=Q59E37 Q59E37 Dmel\CG32547 PTHR24238:SF85 G-PROTEIN COUPLED RECEPTOR OREXIN RECEPTOR TYPE 2-LIKE PROTEIN neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0028700|UniProtKB=Q9U9Q1 Q9U9Q1 RfC38 PTHR11669:SF1 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 3 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 DROME|FlyBase=FBgn0037882|UniProtKB=Q9VGR0 Q9VGR0 Dmel\CG17187 PTHR44313:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex disassembly#GO:0032984;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;cellular component disassembly#GO:0022411;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 chaperone#PC00072 DROME|FlyBase=FBgn0031639|UniProtKB=Q8MSS7 Q8MSS7 mRpS2 PTHR12534:SF0 30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR SMALL RIBOSOMAL SUBUNIT PROTEIN US2M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 DROME|FlyBase=FBgn0037138|UniProtKB=Q9VNX4 Q9VNX4 P5CDh1 PTHR42862:SF1 DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL-RELATED aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic side of plasma membrane#GO:0009898;organelle lumen#GO:0043233;mitochondrion#GO:0005739;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 DROME|FlyBase=FBgn0036916|UniProtKB=Q9VW53 Q9VW53 Mtr3 PTHR11953:SF2 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT MTR3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;snRNA 3'-end processing#GO:0034472;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;RNA 3'-end processing#GO:0031123;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;snRNA metabolic process#GO:0016073;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;snRNA processing#GO:0016180;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 exoribonuclease#PC00099;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039049|UniProtKB=Q9VCR2 Q9VCR2 Dmel\CG6726 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0036341|UniProtKB=Q9VU45 Q9VU45 Syx13 PTHR19957:SF38 SYNTAXIN T-SNARE DOMAIN-CONTAINING PROTEIN 1 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 cytoplasm#GO:0005737;SNARE complex#GO:0031201;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Parkinson disease#P00049>Syntaxin#P01215;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772 DROME|FlyBase=FBgn0005386|UniProtKB=Q9VW15 Q9VW15 ash1 PTHR46147:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0031528|UniProtKB=M9PED9 M9PED9 Dmel\CG15412 PTHR16134:SF1 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX AND LEUCINE-RICH PROTEIN 22 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;photoperiodism#GO:0009648;macromolecule metabolic process#GO:0043170;response to external stimulus#GO:0009605;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of circadian rhythm#GO:0042752;response to radiation#GO:0009314;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to light stimulus#GO:0009416 cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0027619|UniProtKB=Q7K550 Q7K550 eIF3j PTHR21681:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 DROME|FlyBase=FBgn0031011|UniProtKB=Q9VWJ1 Q9VWJ1 Dmel\CG8034 PTHR11360:SF163 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 9-LIKE PROTEIN transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0020416|UniProtKB=Q8MM24 Q8MM24 Idgf1 PTHR11177:SF235 CHITINASE CHITINASE-LIKE PROTEIN IDGF1-RELATED chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 DROME|FlyBase=FBgn0266101|UniProtKB=X2JCR2 X2JCR2 CG18632 PTHR24155:SF10 OSTEOCLAST-STIMULATING FACTOR 1 OSTEOCLAST-STIMULATING FACTOR 1 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 DROME|FlyBase=FBgn0031913|UniProtKB=Q9VM12 Q9VM12 Dmel\CG5958 PTHR10174:SF212 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED MIP26555P1 binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0266599|UniProtKB=P11147 P11147 Hsc70-4 PTHR19375:SF582 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 DROME|FlyBase=FBgn0051559|UniProtKB=Q9VNL4 Q9VNL4 CG31559 PTHR45669:SF18 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN CG12206-RELATED GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN CG12206-RELATED metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0030439|UniProtKB=Q9VYH7 Q9VYH7 Dmel\CG12716 PTHR10913:SF45 FOLLISTATIN-RELATED AGRIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0032857|UniProtKB=A4V0X6 A4V0X6 38C.42 PTHR13539:SF3 CALMODULIN-LYSINE N-METHYLTRANSFERASE CALMODULIN-LYSINE N-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032925|UniProtKB=Q9VIF0 Q9VIF0 Noc2 PTHR12687:SF4 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;90S preribosome#GO:0030686;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0030300|UniProtKB=Q9VYY8 Q9VYY8 Sk1 PTHR12358:SF112 SPHINGOSINE KINASE SPHINGOSINE KINASE lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingoid biosynthetic process#GO:0046520 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0036850|UniProtKB=Q9VVX0 Q9VVX0 Gem2 PTHR12794:SF0 GEMIN2 GEM-ASSOCIATED PROTEIN 2 protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0029715|UniProtKB=Q9W4J4 Q9W4J4 Dmel\CG11444 PTHR22055:SF0 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0262029|UniProtKB=M9MRE4 M9MRE4 dachs PTHR13140:SF498 MYOSIN DACHS, ISOFORM E microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane#GO:0016020;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0030328|UniProtKB=Q9VYV4 Q9VYV4 Amun PTHR21521:SF0 AMUN, ISOFORM A AMUN, ISOFORM A DROME|FlyBase=FBgn0000137|UniProtKB=P09775 P09775 ase PTHR13935:SF169 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE COMPLEX PROTEIN T5-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0003507|UniProtKB=P52172 P52172 srp PTHR10071:SF337 TRANSCRIPTION FACTOR GATA FAMILY MEMBER BOX A-BINDING FACTOR-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0038486|UniProtKB=Q9VEM4 Q9VEM4 Dmel\CG5265 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 DROME|FlyBase=FBgn0036323|UniProtKB=Q9VU24 Q9VU24 Dmel\CG14118 PTHR13966:SF19 ENDONUCLEASE RELATED DNA_RNA NON-SPECIFIC ENDONUCLEASE DOMAIN-CONTAINING PROTEIN-RELATED DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520 DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309 cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0266437|UniProtKB=A0A1L4AAC2 A0A1L4AAC2 Dmel\CG45067 PTHR22730:SF1 PROMININ PROM PROTEIN PROMININ-LIKE PROTEIN cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;vesicle#GO:0031982;actin-based cell projection#GO:0098858;microvillus#GO:0005902;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944 DROME|FlyBase=FBgn0051198|UniProtKB=Q8IN25 Q8IN25 Dmel\CG31198 PTHR11533:SF308 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;primary metabolic process#GO:0044238;peptide catabolic process#GO:0043171;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0041164|UniProtKB=Q6J5K9 Q6J5K9 armi PTHR10887:SF419 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV10L1 ISOFORM X1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytosol#GO:0005829 RNA helicase#PC00032 DROME|FlyBase=FBgn0032728|UniProtKB=Q9VJ29 Q9VJ29 Tango6 PTHR20959:SF1 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG export from cell#GO:0140352;establishment of protein localization#GO:0045184;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;macromolecule localization#GO:0033036;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;localization#GO:0051179;protein secretion#GO:0009306;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810 DROME|FlyBase=FBgn0261859|UniProtKB=Q9VFD3 Q9VFD3 Dmel\CG42788 PTHR10316:SF68 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED FRM-8 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of protein localization to membrane#GO:1905475;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;cell communication#GO:0007154 adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell-cell junction#GO:0005911 DROME|FlyBase=FBgn0038414|UniProtKB=Q9VEW9 Q9VEW9 Dmel\CG6901 PTHR23529:SF2 GH19118P-RELATED GH19118P-RELATED DROME|FlyBase=FBgn0051100|UniProtKB=A0A0B4KGW3 A0A0B4KGW3 Glug PTHR48021:SF39 FAMILY NOT NAMED MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0038859|UniProtKB=Q9VDE1 Q9VDE1 Obp93a PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0052177|UniProtKB=Q9VVJ5 Q9VVJ5 Ndfip PTHR13396:SF5 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY INTERACTING PROTEIN regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification process#GO:0031399;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of protein ubiquitination#GO:0031396;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0085476|UniProtKB=Q4V566 Q4V566 CG9966 PTHR11610:SF177 LIPASE IP13478P-RELATED lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0025456|UniProtKB=Q9VEK7 Q9VEK7 CREG PTHR13343:SF39 CREG1 PROTEIN CELLULAR REPRESSOR OF E1A-STIMULATED GENES, ISOFORM A extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039709|UniProtKB=Q9VAF5 Q9VAF5 Cad99C PTHR24026:SF141 FAT ATYPICAL CADHERIN-RELATED CADHERIN DOMAIN-CONTAINING PROTEIN cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cell-cell adhesion#GO:0098609;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 DROME|FlyBase=FBgn0033085|UniProtKB=Q4QPU3 Q4QPU3 Dmel\CG15908 PTHR28052:SF1 UPF0545 PROTEIN C22ORF39 SYNAPTIC PLASTICITY REGULATOR PANTS DROME|FlyBase=FBgn0028563|UniProtKB=Q7KK97 Q7KK97 sut1 PTHR23503:SF127 SOLUTE CARRIER FAMILY 2 FI08437P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 carbohydrate transport#GO:0008643;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;carbohydrate transmembrane transport#GO:0034219;transmembrane transport#GO:0055085 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0029928|UniProtKB=Q9W3T3 Q9W3T3 Dmel\CG3032 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0033889|UniProtKB=A1Z9K0 A1Z9K0 EP(2)2054 PTHR10887:SF419 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV10L1 ISOFORM X1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA helicase#PC00032 DROME|FlyBase=FBgn0010612|UniProtKB=Q9VKM3 Q9VKM3 ATPsynG PTHR12386:SF12 ATP SYNTHASE SUBUNIT ATP SYNTHASE F(0) COMPLEX SUBUNIT G, MITOCHONDRIAL-RELATED proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137 membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002 DROME|FlyBase=FBgn0040256|UniProtKB=Q9VGT8 Q9VGT8 Ugt35C1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0051952|UniProtKB=Q9VQQ4 Q9VQQ4 CG15413 PTHR47372:SF11 DAUER UP-REGULATED-RELATED RE19971P DROME|FlyBase=FBgn0283521|UniProtKB=Q867Z4 Q867Z4 lola PTHR23110:SF114 BTB DOMAIN TRANSCRIPTION FACTOR LONGITUDINALS LACKING PROTEIN, ISOFORMS F_I_K_T regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0035510|UniProtKB=Q9VZG2 Q9VZG2 Cpr64Aa PTHR12236:SF79 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 64AA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0026083|UniProtKB=Q9W4M7 Q9W4M7 tyf PTHR23202:SF130 WASP INTERACTING PROTEIN-RELATED MULTI SEX COMBS, ISOFORM A-RELATED nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0036179|UniProtKB=Q9VTK6 Q9VTK6 Dmel\CG7368 PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0264740|UniProtKB=Q9VCG2 Q9VCG2 CG43998 PTHR12499:SF30 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN system process#GO:0003008;multicellular organismal process#GO:0032501;neuromuscular process#GO:0050905;nervous system process#GO:0050877 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0036836|UniProtKB=Q9VVV4 Q9VVV4 Dmel\CG11619 PTHR22958:SF43 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 DROME|FlyBase=FBgn0039470|UniProtKB=Q9VB94 Q9VB94 DmelL7 PTHR11610:SF178 LIPASE FI01825P-RELATED hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0034961|UniProtKB=Q9W1C8 Q9W1C8 Dmel\CG3163 PTHR21505:SF8 MADF DOMAIN-CONTAINING PROTEIN-RELATED DPT-YFP REPRESSOR BY OVEREXPRESSION, ISOFORM D-RELATED DROME|FlyBase=FBgn0010548|UniProtKB=A0A0C4DHC8 A0A0C4DHC8 Aldh-III PTHR43570:SF16 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 DROME|FlyBase=FBgn0030477|UniProtKB=Q9VYE0 Q9VYE0 dmrt11E PTHR12322:SF53 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX-MAB RELATED 11E-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036292|UniProtKB=Q9VTY5 Q9VTY5 anon-WO0172774.52 PTHR14205:SF15 WD-REPEAT PROTEIN EARP AND GARP COMPLEX-INTERACTING PROTEIN 1 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 DROME|FlyBase=FBgn0032897|UniProtKB=Q9VII1 Q9VII1 bero PTHR33562:SF18 ATILLA, ISOFORM B-RELATED-RELATED RE19849P-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0010348|UniProtKB=P61209 P61209 Arf1 PTHR11711:SF479 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 DROME|FlyBase=FBgn0030926|UniProtKB=Q9VWU1 Q9VWU1 psh PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0036191|UniProtKB=Q9VTL9 Q9VTL9 Sugb PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0264495|UniProtKB=Q8INR6 Q8INR6 gpp PTHR21451:SF0 HISTONE H3 METHYLTRANSFERASE HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular response to stress#GO:0033554;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;regulation of cell cycle process#GO:0010564;cellular component assembly#GO:0022607;cell cycle checkpoint signaling#GO:0000075;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;heterochromatin formation#GO:0031507;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;DNA integrity checkpoint signaling#GO:0031570;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;DNA damage checkpoint signaling#GO:0000077 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0035577|UniProtKB=Q9VZ81 Q9VZ81 CT33170 PTHR45973:SF8 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 49 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 DROME|FlyBase=FBgn0036497|UniProtKB=Q9VUN3 Q9VUN3 Ran-like PTHR24071:SF0 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein import into nucleus#GO:0006606;protein transport#GO:0015031;ribosome biogenesis#GO:0042254;gene expression#GO:0010467;protein export from nucleus#GO:0006611;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;organelle localization#GO:0051640;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;biosynthetic process#GO:0009058;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;poly(A)+ mRNA export from nucleus#GO:0016973;intracellular protein localization#GO:0008104;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 small GTPase#PC00208 DROME|FlyBase=FBgn0033468|UniProtKB=A1Z823 A1Z823 Dmel\CG1418 PTHR19317:SF0 PRENYLATED RAB ACCEPTOR 1-RELATED PRENYLATED RAB ACCEPTOR PROTEIN 1 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0003416|UniProtKB=Q9VXH3 Q9VXH3 sl PTHR10336:SF159 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;signal transduction#GO:0007165;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;metabolic process#GO:0008152;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;organophosphate metabolic process#GO:0019637;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;phosphatidylinositol metabolic process#GO:0046488;transport#GO:0006810;lipid metabolic process#GO:0006629;establishment of localization#GO:0051234 ruffle#GO:0001726;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 EGF receptor signaling pathway#P00018>PLCgamma#P00556;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;PDGF signaling pathway#P00047>PLCgamma#P01171;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;VEGF signaling pathway#P00056>PLC-gamma#P01414;FGF signaling pathway#P00021>PLCgamma#P00638;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362 DROME|FlyBase=FBgn0028872|UniProtKB=M9MSI4 M9MSI4 DS05899.7 PTHR45712:SF22 AGAP008170-PA LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 4 DROME|FlyBase=FBgn0261588|UniProtKB=A0A0B4JD55 A0A0B4JD55 pdm3 PTHR11636:SF5 POU DOMAIN POU DOMAIN MOTIF 3, ISOFORM F double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0032057|UniProtKB=Q9VLJ2 Q9VLJ2 Dmel\CG9287 PTHR43142:SF12 CARBOXYLIC ESTER HYDROLASE CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN-RELATED hydrolase#PC00121 DROME|FlyBase=FBgn0030593|UniProtKB=Q9VY05 Q9VY05 Dmel\CG9512 PTHR11552:SF229 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE ECDYSONE OXIDASE-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0013275|UniProtKB=P82910 P82910 Hsp70Aa PTHR19375:SF518 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN AA-RELATED ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Hsp70 family chaperone#PC00027;chaperone#PC00072 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 DROME|FlyBase=FBgn0038921|UniProtKB=Q9VD59 Q9VD59 Theg PTHR15901:SF17 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN TESTICULAR HAPLOID EXPRESSED GENE PROTEIN-LIKE DROME|FlyBase=FBgn0043783|UniProtKB=Q9VP02 Q9VP02 Galm1 PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824 glucose metabolic process#GO:0006006;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637 epimerase/racemase#PC00096 DROME|FlyBase=FBgn0027296|UniProtKB=Q9W501 Q9W501 temp PTHR11129:SF3 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0033028|UniProtKB=Q7JWI7 Q7JWI7 hrm PTHR11360:SF293 MONOCARBOXYLATE TRANSPORTER HERMES, ISOFORM A transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0004652|UniProtKB=Q8IN81 Q8IN81 fru PTHR23110:SF107 BTB DOMAIN TRANSCRIPTION FACTOR SEX DETERMINATION PROTEIN FRUITLESS regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0015331|UniProtKB=Q9V3C0 Q9V3C0 abs PTHR47958:SF103 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX41-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA helicase#PC00032 DROME|FlyBase=FBgn0024897|UniProtKB=Q9V3N9 Q9V3N9 b6 PTHR19277:SF161 PENTRAXIN B6 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033061|UniProtKB=Q8T3Z4 Q8T3Z4 SmydA-5 PTHR46455:SF2 SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A AT24727P nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0051716|UniProtKB=M9PB92 M9PB92 Cnot4 PTHR12603:SF0 CCR4-NOT TRANSCRIPTION COMPLEX RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein metabolic process#GO:0019538;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;modification-dependent protein catabolic process#GO:0019941;positive regulation of mRNA catabolic process#GO:0061014;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0040238|UniProtKB=A0A0B4K651 A0A0B4K651 Best1 PTHR10736:SF65 BESTROPHIN BESTROPHIN 1, ISOFORM C-RELATED monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0037182|UniProtKB=A8JNX0 A8JNX0 ArfGAP3 PTHR45686:SF4 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0023545|UniProtKB=Q8T4E1 Q8T4E1 PIG-K PTHR48067:SF1 GPI-ANCHOR TRANSAMIDASE GPI-ANCHOR TRANSAMIDASE catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;GPI anchored protein biosynthesis#GO:0180046;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;caspase complex#GO:0008303;peptidase complex#GO:1905368;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0001086|UniProtKB=Q24044 Q24044 fzy PTHR19918:SF8 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG enzyme regulator activity#GO:0030234;protein-containing complex binding#GO:0044877;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;binding#GO:0005488;enzyme activator activity#GO:0008047 metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0263512|UniProtKB=X2JDS9 X2JDS9 Vsx2 PTHR46892:SF3 VISUAL SYSTEM HOMEOBOX 2 VISUAL SYSTEM HOMEOBOX 2 nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0053082|UniProtKB=Q86B65 Q86B65 Rpp21 PTHR14742:SF0 RIBONUCLEASE P SUBUNIT P21 RIBONUCLEASE P PROTEIN SUBUNIT P21 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;cellular anatomical structure#GO:0110165;nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231;endonuclease complex#GO:1905348;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 endoribonuclease#PC00094 DROME|FlyBase=FBgn0040283|UniProtKB=Q9VCD8 Q9VCD8 SMC1 PTHR18937:SF12 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0033366|UniProtKB=A1Z7M8 A1Z7M8 Ance-4 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0030661|UniProtKB=Q9VXS8 Q9VXS8 Alp11 PTHR11596:SF91 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0053465|UniProtKB=A1ZA51 A1ZA51 HDC06631 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0266083|UniProtKB=Q9W198 Q9W198 ocm PTHR11267:SF207 T-BOX PROTEIN-RELATED OVER COMPENSATING MALES, ISOFORM A transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 DROME|FlyBase=FBgn0259722|UniProtKB=B7Z107 B7Z107 Dmel\CG42376 PTHR46690:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cytochrome complex assembly#GO:0017004 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 chaperone#PC00072 DROME|FlyBase=FBgn0036324|UniProtKB=Q9VU25 Q9VU25 Dmel\CG12520 PTHR38926:SF84 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED F-BOX DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 DROME|FlyBase=FBgn0039092|UniProtKB=Q9VCK8 Q9VCK8 Dmel\CG16723 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0022355|UniProtKB=Q9VWV6 Q9VWV6 Tsf1 PTHR11485:SF57 TRANSFERRIN TRANSFERRIN iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;extracellular region#GO:0005576;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;recycling endosome#GO:0055037 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0042693|UniProtKB=Q8IN89 Q8IN89 wrd PTHR10257:SF3 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B WELL-ROUNDED, ISOFORM B enzyme activator activity#GO:0008047;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 DROME|FlyBase=FBgn0036648|UniProtKB=Q9VV83 Q9VV83 CG4098-PA PTHR13030:SF15 NUDIX HYDROLASE NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0034381|UniProtKB=A1ZBC7 A1ZBC7 List PTHR11616:SF339 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943 amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;glycine transport#GO:0015816;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 DROME|FlyBase=FBgn0015714|UniProtKB=Q9V770 Q9V770 Cyp6a17 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0031145|UniProtKB=Q9VRD6 Q9VRD6 Ntf-2 PTHR12612:SF48 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0026080|UniProtKB=Q960X4 Q960X4 Tip60 PTHR10615:SF219 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT5 catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 DROME|FlyBase=FBgn0031327|UniProtKB=Q9VPZ5 Q9VPZ5 CT16527 PTHR11559:SF429 CARBOXYLESTERASE ESTERASE P-RELATED esterase#PC00097 DROME|FlyBase=FBgn0010097|UniProtKB=P42271 P42271 gammaTub37C PTHR11588:SF540 TUBULIN TUBULIN GAMMA CHAIN anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;microtubule nucleation#GO:0007020;microtubule polymerization#GO:0046785;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 tubulin#PC00228;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0265083|UniProtKB=A0A0B4KFX0 A0A0B4KFX0 Dmel\CG44194 PTHR13639:SF2 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 chaperone#PC00072 DROME|FlyBase=FBgn0036842|UniProtKB=Q9VVW2 Q9VVW2 Ugt316A1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0004867|UniProtKB=P31009 P31009 RpS2 PTHR13718:SF4 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 DROME|FlyBase=FBgn0036336|UniProtKB=Q9VU37 Q9VU37 Icmt PTHR12714:SF9 PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0051482|UniProtKB=Q9VI35 Q9VI35 CG2337 PTHR10334:SF620 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0038929|UniProtKB=Q9VD50 Q9VD50 Dmel\CG13408 PTHR33964:SF2 RE45066P-RELATED IP09356P DROME|FlyBase=FBgn0033437|UniProtKB=A1Z7X8 A1Z7X8 Dmel\CG12926 PTHR10174:SF216 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN-RELATED anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0033903|UniProtKB=Q7JZE8 Q7JZE8 Dmel\CG8323 PTHR45928:SF1 RE38146P RE38146P DROME|FlyBase=FBgn0035787|UniProtKB=Q9VS75 Q9VS75 Dmel\CG8543 PTHR39068:SF2 LARVAL/PUPAL CUTICLE PROTEIN H1C-LIKE PROTEIN-RELATED MIP24391P DROME|FlyBase=FBgn0030007|UniProtKB=Q9W3J5 Q9W3J5 alpha-PheRS PTHR11538:SF40 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0028407|UniProtKB=Q0E9B7 Q0E9B7 Drep3 PTHR12306:SF15 CELL DEATH ACTIVATOR CIDE DNAATION FACTOR-RELATED PROTEIN 1, ISOFORM B-RELATED cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;programmed cell death#GO:0012501 DROME|FlyBase=FBgn0038718|UniProtKB=Q9VDV7 Q9VDV7 Dmel\CG17752 PTHR24064:SF467 SOLUTE CARRIER FAMILY 22 MEMBER FI01439P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0028369|UniProtKB=Q9W4T9 Q9W4T9 kirre PTHR11640:SF170 NEPHRIN IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0053289|UniProtKB=Q7KTW2 Q7KTW2 ppk5 PTHR11690:SF243 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 12-RELATED channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0039465|UniProtKB=Q9VB99 Q9VB99 Tsp97E PTHR19282:SF452 TETRASPANIN LD03691P scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038693|UniProtKB=Q9VDY5 Q9VDY5 unc79 PTHR21696:SF2 PROTEIN UNC-79 HOMOLOG PROTEIN UNC-79 HOMOLOG DROME|FlyBase=FBgn0027597|UniProtKB=Q9Y153 Q9Y153 Dmel\CG17712 PTHR43818:SF11 BCDNA.GH03377 BCDNA.GH03377 dehydrogenase#PC00092 DROME|FlyBase=FBgn0039153|UniProtKB=Q9VCD0 Q9VCD0 GatB PTHR11659:SF5 GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ligase#PC00142;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0051712|UniProtKB=Q9VL63 Q9VL63 Arglu1 PTHR31711:SF1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;nucleus#GO:0005634 DROME|FlyBase=FBgn0030880|UniProtKB=Q9VX04 Q9VX04 FBpp0074269 PTHR19143:SF470 FIBRINOGEN/TENASCIN/ANGIOPOEITIN GH05177P-RELATED extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0032727|UniProtKB=Q9VJ31 Q9VJ31 Bhmt PTHR46015:SF1 ZGC:172121 BETAINE-HOMOCYSTEINE S-METHYLTRANSFERASE-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024 DROME|FlyBase=FBgn0040070|UniProtKB=Q9V429 Q9V429 Trx2 PTHR10438:SF475 THIOREDOXIN THIOREDOXIN disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 DROME|FlyBase=FBgn0038315|UniProtKB=B7Z0K3 B7Z0K3 Dmel\CG14866 PTHR22802:SF459 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN CONTAINING 19A binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0039501|UniProtKB=Q9VB58 Q9VB58 TTLL6B PTHR12241:SF161 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL6 catalytic activity, acting on a protein#GO:0140096;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;binding#GO:0005488 microtubule bundle formation#GO:0001578;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0264270|UniProtKB=P19339 P19339 Sxl PTHR24012:SF885 RNA BINDING PROTEIN PROTEIN SEX-LETHAL binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0039714|UniProtKB=Q9VAF0 Q9VAF0 Zip99C PTHR16950:SF16 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER ZIP13 transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0039482|UniProtKB=Q9VB80 Q9VB80 Dmel\CG14258 PTHR11008:SF25 PROTEIN TAKEOUT-LIKE PROTEIN IP09473P-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0039159|UniProtKB=Q9VCC3 Q9VCC3 mRpS24 PTHR21244:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN US3M ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0039336|UniProtKB=Q9VBR0 Q9VBR0 Dmel\CG4553 PTHR13475:SF6 NEUGRIN FI11059P cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;mitochondrial ribosome assembly#GO:0061668;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0027500|UniProtKB=Q9VV79 Q9VV79 spd-2 PTHR13030:SF14 NUDIX HYDROLASE BCDNA.LD24702 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0011293|UniProtKB=Q27377 Q27377 a10 PTHR11257:SF12 CHEMOSENSORY PROTEIN-RELATED EJACULATORY BULB-SPECIFIC PROTEIN 3-RELATED DROME|FlyBase=FBgn0021795|UniProtKB=Q7KLX3 Q7KLX3 Tapdelta PTHR12731:SF1 TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0039923|UniProtKB=Q9V4F9 Q9V4F9 MED26 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217 DROME|FlyBase=FBgn0039908|UniProtKB=Q8IMC6 Q8IMC6 Asator PTHR11909:SF300 CASEIN KINASE-RELATED TAU-TUBULIN KINASE HOMOLOG ASATOR catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 DROME|FlyBase=FBgn0028948|UniProtKB=Q9V421 Q9V421 BG:BACR44L22.3 PTHR10127:SF914 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0036770|UniProtKB=Q9VVM6 Q9VVM6 Prestin PTHR11814:SF189 SULFATE TRANSPORTER FI18412P1 dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 DROME|FlyBase=FBgn0037963|UniProtKB=Q9VGG5 Q9VGG5 Cad87A PTHR24028:SF146 CADHERIN-87A CADHERIN-87A cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 DROME|FlyBase=FBgn0036373|UniProtKB=Q9VU85 Q9VU85 Tgi PTHR17604:SF7 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 TONDU-DOMAIN-CONTAINING GROWTH INHIBITOR, ISOFORM A protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 transcription cofactor#PC00217 DROME|FlyBase=FBgn0050412|UniProtKB=Q8MLS5 Q8MLS5 CG9803 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0030067|UniProtKB=Q9W3B2 Q9W3B2 Rbm13 PTHR23405:SF4 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED PROTEIN MAK16 HOMOLOG macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 DROME|FlyBase=FBgn0031361|UniProtKB=Q9VQ40 Q9VQ40 Dmel\CG17652 PTHR12416:SF3 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RNA binding#GO:0003723;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0030228|UniProtKB=Q9W2S3 Q9W2S3 BTBD9 PTHR46306:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 9 BTB_POZ DOMAIN-CONTAINING PROTEIN 9 regulation of signaling#GO:0023051;rhythmic process#GO:0048511;circadian rhythm#GO:0007623;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037376|UniProtKB=Q0KIB3 Q0KIB3 Hat1 PTHR12046:SF0 HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0032815|UniProtKB=Q9VIS7 Q9VIS7 Dmel\CG10462 PTHR24396:SF19 ZINC FINGER PROTEIN FI01119P transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0039080|UniProtKB=Q9VCM0 Q9VCM0 Ir94h PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0035216|UniProtKB=Q9W0F7 Q9W0F7 Dmel\CG9168 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0044511|UniProtKB=Q8I0J3 Q8I0J3 mRpS21 PTHR21109:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0030377|UniProtKB=Q9I7S9 Q9I7S9 Dmel\CG1924 PTHR11073:SF1 CALRETICULIN AND CALNEXIN CALNEXIN 14D-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 response to stimulus#GO:0050896;catabolic process#GO:0009056;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0029863|UniProtKB=Q9W408 Q9W408 Dmel\CG3823 PTHR10174:SF222 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED GH10083P-RELATED phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0085474|UniProtKB=Q4V6L7 Q4V6L7 CG13513 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0028552|UniProtKB=Q9U6R9 Q9U6R9 gammaSnap1 PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 DROME|FlyBase=FBgn0030834|UniProtKB=Q9VX62 Q9VX62 Dmel\CG8675 PTHR22876:SF5 ZGC:101016 CHROMOSOME 9 OPEN READING FRAME 85 DROME|FlyBase=FBgn0003482|UniProtKB=Q8SZ30 Q8SZ30 spn-D PTHR22942:SF66 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER DNA REPAIR PROTEIN RAD51 HOMOLOG 3 ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 mitotic recombination#GO:0006312;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;double-strand break repair#GO:0006302;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0002570|UniProtKB=P07190 P07190 Mal-A1 PTHR10357:SF233 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A1 oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152 amylase#PC00048;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0050125|UniProtKB=A1ZBG7 A1ZBG7 Ir56a PTHR42643:SF39 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 56A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0033635|UniProtKB=D3DMU9 D3DMU9 Prip PTHR19139:SF293 AQUAPORIN TRANSPORTER MIP17260P water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 transport#GO:0006810;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;fluid transport#GO:0042044 apical part of cell#GO:0045177;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;apical plasma membrane#GO:0016324 transporter#PC00227 DROME|FlyBase=FBgn0085481|UniProtKB=A8JNT2 A8JNT2 CG33999 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 transferase#PC00220 DROME|FlyBase=FBgn0058045|UniProtKB=Q8SYG3 Q8SYG3 BcDNA:RE63412 PTHR24067:SF3 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 DROME|FlyBase=FBgn0025638|UniProtKB=Q9W5E1 Q9W5E1 Roc1a PTHR11210:SF2 RING BOX E3 UBIQUITIN-PROTEIN LIGASE RBX1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0039071|UniProtKB=Q9VCN3 Q9VCN3 bb8 PTHR11606:SF7 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 DROME|FlyBase=FBgn0032120|UniProtKB=Q7KTG6 Q7KTG6 CG18419 PTHR24092:SF148 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;phospholipid transport#GO:0015914;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0016119|UniProtKB=Q24407 Q24407 ATPsynCF6 PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT F6, MITOCHONDRIAL proton-transporting ATP synthase complex#GO:0045259;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0030345|UniProtKB=A0A6H2EG45 A0A6H2EG45 Dmel\CG1847 PTHR11242:SF20 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED AIP_AIPL N-TERMINAL FKBP-TYPE PPIASE DOMAIN-CONTAINING PROTEIN macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 DROME|FlyBase=FBgn0019890|UniProtKB=Q9V414 Q9V414 Smg5 PTHR15696:SF7 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;RNA binding#GO:0003723;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0022800|UniProtKB=Q9VBW3 Q9VBW3 Cad96Ca PTHR24416:SF621 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE KINASE RECEPTOR CAD96CA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0262017|UniProtKB=F3YD83 F3YD83 CG42830-RA PTHR13293:SF6 AKIRIN-RELATED AKIRIN-RELATED transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of response to external stimulus#GO:0032103;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;positive regulation of RNA metabolic process#GO:0051254;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0263026|UniProtKB=M9NEV9 M9NEV9 Dmel\CG43321 PTHR33904:SF1 ESSENTIAL MCU REGULATOR, MITOCHONDRIAL ESSENTIAL MCU REGULATOR, MITOCHONDRIAL calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;mitochondrial calcium ion homeostasis#GO:0051560;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 calcium channel complex#GO:0034704;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;transporter complex#GO:1990351 DROME|FlyBase=FBgn0001995|UniProtKB=Q9V3D0 Q9V3D0 mRpL4 PTHR10746:SF18 50S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of cell communication#GO:0010646;positive regulation of Notch signaling pathway#GO:0045747;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;post-transcriptional regulation of gene expression#GO:0010608;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 DROME|FlyBase=FBgn0004425|UniProtKB=Q08694 Q08694 LysB PTHR11407:SF63 LYSOZYME C LYSOZYME catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;lysozyme activity#GO:0003796 glycosidase#PC00110 DROME|FlyBase=FBgn0038510|UniProtKB=A8JR34 A8JR34 Dmel\CG14331 PTHR12480:SF19 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD CUPIN-LIKE DOMAIN-CONTAINING PROTEIN dioxygenase activity#GO:0051213;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;sequence-specific DNA binding#GO:0043565;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;positive regulation of cellular component organization#GO:0051130;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of protein-containing complex disassembly#GO:0043244;regulation of translation#GO:0006417;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038262|UniProtKB=Q9VFG0 Q9VFG0 Dmel\CG14857 PTHR24064:SF467 SOLUTE CARRIER FAMILY 22 MEMBER FI01439P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0033304|UniProtKB=Q9V4U9 Q9V4U9 Cyp6a13 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0037339|UniProtKB=Q9VND3 Q9VND3 Pi4KIIalpha PTHR12865:SF1 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;Golgi organization#GO:0007030;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vesicle organization#GO:0016050;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;endomembrane system organization#GO:0010256;organophosphate metabolic process#GO:0019637;organelle organization#GO:0006996;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 DROME|FlyBase=FBgn0035245|UniProtKB=Q9W0C4 Q9W0C4 GC PTHR12639:SF6 VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE lyase activity#GO:0016829;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 vitamin K metabolic process#GO:0042373;ketone metabolic process#GO:0042180;metabolic process#GO:0008152;cellular process#GO:0009987 DROME|FlyBase=FBgn0039768|UniProtKB=Q9VA78 Q9VA78 Dmel\CG15533 PTHR10340:SF29 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;lipase activity#GO:0016298;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;organophosphate catabolic process#GO:0046434;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sphingolipid catabolic process#GO:0030149;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764 hydrolase#PC00121;phosphodiesterase#PC00185 DROME|FlyBase=FBgn0023496|UniProtKB=O46107 O46107 Lip1 PTHR11005:SF145 LYSOSOMAL ACID LIPASE-RELATED LIPASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0067317|UniProtKB=B9A0M5 B9A0M5 Cby PTHR21533:SF19 LEUCINE-RICH PROTEIN LEUCINE-RICH PROTEIN DROME|FlyBase=FBgn0014026|UniProtKB=P46223 P46223 RpL7A PTHR23105:SF1 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0030271|UniProtKB=Q9VZ25 Q9VZ25 Dmel\CG15202 PTHR39957:SF2 AT09846P1-RELATED GEO11553P1 DROME|FlyBase=FBgn0042119|UniProtKB=Q9I7Q5 Q9I7Q5 Cpr65Au PTHR10380:SF192 CUTICLE PROTEIN CUTICULAR PROTEIN 65AU, ISOFORM A-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0011762|UniProtKB=Q24317 Q24317 Prim1 PTHR10536:SF0 DNA PRIMASE SMALL SUBUNIT DNA PRIMASE SMALL SUBUNIT catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;DNA replication#GO:0006260;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227 primase#PC00189 DNA replication#P00017>Primase#P00528 DROME|FlyBase=FBgn0034246|UniProtKB=A1ZAW0 A1ZAW0 Dcr-2 PTHR14950:SF36 DICER-RELATED ENDORIBONUCLEASE DCR-2 catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;binding#GO:0005488;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;cell death#GO:0008219;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;siRNA processing#GO:0030422;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;execution phase of apoptosis#GO:0097194;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;DNA catabolic process#GO:0006308;apoptotic DNA fragmentation#GO:0006309;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0052187|UniProtKB=Q9VVK9 Q9VVK9 CG5584 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED DROME|FlyBase=FBgn0012037|UniProtKB=Q10714 Q10714 Ance PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0039801|UniProtKB=Q9VA41 Q9VA41 Npc2h PTHR11306:SF55 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED GEO08227P1-RELATED lipid binding#GO:0008289;steroid binding#GO:0005496;binding#GO:0005488;sterol binding#GO:0032934 transport#GO:0006810;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;establishment of localization#GO:0051234;sterol transport#GO:0015918;macromolecule localization#GO:0033036;lipid transport#GO:0006869 DROME|FlyBase=FBgn0011336|UniProtKB=Q9XZ53 Q9XZ53 Stt3B PTHR13872:SF49 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;protein modification process#GO:0036211;primary metabolic process#GO:0044238 membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0038601|UniProtKB=Q9VE94 Q9VE94 Polr1E PTHR14440:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase I promoter#GO:0006361;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974 DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0037325|UniProtKB=Q7JWT4 Q7JWT4 CKIalpha like PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 DROME|FlyBase=FBgn0030207|UniProtKB=Q9W2U5 Q9W2U5 Dmel\CG2887 PTHR24078:SF586 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 5 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 DROME|FlyBase=FBgn0029006|UniProtKB=Q9V853 Q9V853 Smurf PTHR11254:SF395 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Activin beta signaling pathway#P06210>LACK#P06230;DPP signaling pathway#P06213>LACK#P06278;GBB signaling pathway#P06214>LACK#P06303;MYO signaling pathway#P06215>LACK#P06309;TGF-beta signaling pathway#P00052>Smurfs#P01279;ALP23B signaling pathway#P06209>LACK#P06219;SCW signaling pathway#P06216>LACK#P06321;BMP/activin signaling pathway-drosophila#P06211>Smurf#P06243;DPP-SCW signaling pathway#P06212>LACK#P06269 DROME|FlyBase=FBgn0063368|UniProtKB=Q4V4C8 Q4V4C8 Gpb5 PTHR11515:SF13 GLYCOPROTEIN HORMONE BETA CHAIN GLYCOPROTEIN HORMONE BETA 5, ISOFORM A molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 DROME|FlyBase=FBgn0050083|UniProtKB=A1ZA44 A1ZA44 Dmel\CG30083 PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0086706|UniProtKB=Q9VSS1 Q9VSS1 pix PTHR19248:SF32 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY E MEMBER 1 nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;ribonucleoprotein complex binding#GO:0043021;cation binding#GO:0043169;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;iron ion binding#GO:0005506;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;metal ion binding#GO:0046872;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;translational termination#GO:0006415;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0029811|UniProtKB=Q9W471 Q9W471 Cpr5C PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0259245|UniProtKB=B7Z153 B7Z153 DIP-beta PTHR12231:SF87 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN BETA, ISOFORM C-RELATED cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;synapse organization#GO:0050808;cell adhesion#GO:0007155;cellular process#GO:0009987 neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell junction#GO:0030054;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0037141|UniProtKB=Q9VNX1 Q9VNX1 PolH PTHR45873:SF1 DNA POLYMERASE ETA DNA POLYMERASE ETA nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA-directed DNA polymerase activity#GO:0003887 response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;response to radiation#GO:0009314;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;replication fork#GO:0005657;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0001179|UniProtKB=Q02870 Q02870 hay PTHR11274:SF0 RAD25/XP-B DNA REPAIR HELICASE GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE_TRANSLOCASE SUBUNIT XPB ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transferase complex#GO:1990234;nucleotide-excision repair complex#GO:0000109;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009;DNA helicase#PC00011 DROME|FlyBase=FBgn0029843|UniProtKB=Q9W436 Q9W436 Nep1 PTHR11733:SF245 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-1 metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0264001|UniProtKB=A0A6M3Q6L8 A0A6M3Q6L8 bru3 PTHR24012:SF928 RNA BINDING PROTEIN BRUNO 3, ISOFORM Q mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0004698|UniProtKB=Q24595 Q24595 Xpc PTHR12135:SF3 DNA REPAIR PROTEIN XP-C / RAD4 DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0038070|UniProtKB=Q9VG46 Q9VG46 Dmel\CG6753 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0035806|UniProtKB=Q9VS97 Q9VS97 PGRP-SD PTHR11022:SF75 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN SB1-RELATED N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0032294|UniProtKB=Q9VKQ8 Q9VKQ8 Vha16-5 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0002940|UniProtKB=P06002 P06002 ninaE PTHR24240:SF85 OPSIN OPSIN RH1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 DROME|FlyBase=FBgn0036192|UniProtKB=Q9VTM0 Q9VTM0 Pldn PTHR31328:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 cellular pigmentation#GO:0033059;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;cellular localization#GO:0051641;localization#GO:0051179;pigmentation#GO:0043473;organelle localization#GO:0051640 vesicle#GO:0031982;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;BLOC-1 complex#GO:0031083;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;actin filament bundle#GO:0032432;actomyosin#GO:0042641;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;cell-cell contact zone#GO:0044291;cell junction#GO:0030054;neuromuscular junction#GO:0031594;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0032162|UniProtKB=Q9VL66 Q9VL66 Dmel\CG4592 PTHR11941:SF45 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydratase#PC00120;lyase#PC00144 DROME|FlyBase=FBgn0283461|UniProtKB=P41964 P41964 Drs PTHR33147:SF98 DEFENSIN-LIKE PROTEIN 1 DRO1 PROTEIN-RELATED defense response#GO:0006952;response to stimulus#GO:0050896;response to stress#GO:0006950 antimicrobial response protein#PC00051 DROME|FlyBase=FBgn0010287|UniProtKB=Q27896 Q27896 Trf PTHR10126:SF41 TATA-BOX BINDING PROTEIN TBP-RELATED FACTOR macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 RNA metabolism protein#PC00031;general transcription factor#PC00259 Huntington disease#P00029>TBP#P00779;General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 DROME|FlyBase=FBgn0034452|UniProtKB=A1ZBM3 A1ZBM3 Oseg6 PTHR14920:SF0 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT DOMAIN 19 intraciliary transport#GO:0042073;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0002772|UniProtKB=P06742 P06742 Mlc1 PTHR23048:SF33 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN ALKALI intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0050062|UniProtKB=A1Z9D5 A1Z9D5 Dmel\CG30062 PTHR11407:SF63 LYSOZYME C LYSOZYME hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosidase#PC00110 DROME|FlyBase=FBgn0020277|UniProtKB=O02372 O02372 lush PTHR21364:SF1 GENERAL ODORANT-BINDING PROTEIN 19A GENERAL ODORANT-BINDING PROTEIN LUSH binding#GO:0005488 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0033607|UniProtKB=Q1LZ08 Q1LZ08 Uaf1 PTHR19862:SF14 WD REPEAT-CONTAINING PROTEIN 48 WD REPEAT-CONTAINING PROTEIN 48 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 DROME|FlyBase=FBgn0039290|UniProtKB=Q9VBW1 Q9VBW1 Dmel\CG13654 PTHR14319:SF3 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 TRANSMEMBRANE PROTEIN-LIKE PROTEIN cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0051663|UniProtKB=Q9VQ52 Q9VQ52 CG15359 PTHR16172:SF46 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE GH27779P membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0262123|UniProtKB=A0A0B7P7M6 A0A0B7P7M6 l(2)41Ab PTHR16275:SF8 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 LETHAL (2) 41AB, ISOFORM A cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0052374|UniProtKB=Q9VS87 Q9VS87 Dmel\CG32374 PTHR24276:SF97 POLYSERASE-RELATED GH13245P2-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0262617|UniProtKB=A0A6H2EG35 A0A6H2EG35 Nuak PTHR12392:SF0 LADININ 1 LADININ-1 structural protein#PC00211 DROME|FlyBase=FBgn0030809|UniProtKB=Q9VX91 Q9VX91 Ubr1 PTHR21497:SF24 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0015828|UniProtKB=O96880 O96880 TfIIEalpha PTHR13097:SF7 TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 protein-containing complex#GO:0032991;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEalpha#P00669;Transcription regulation by bZIP transcription factor#P00055>TFIIEalpha#P01398;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 DROME|FlyBase=FBgn0015949|UniProtKB=A0A0B4KG96 A0A0B4KG96 hrg PTHR10682:SF10 POLY A POLYMERASE POLYNUCLEOTIDE ADENYLYLTRANSFERASE nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0034304|UniProtKB=A0A0B4KFB5 A0A0B4KFB5 Dmel\CG5742 PTHR12447:SF39 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049 endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0029117|UniProtKB=Q9U4F3 Q9U4F3 Surf1 PTHR23427:SF15 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 1 cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0261112|UniProtKB=Q9VTE9 Q9VTE9 APP-BP1 PTHR10953:SF29 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0050495|UniProtKB=A0A0B4KFB3 A0A0B4KFB3 Dmel\CG30495 PTHR24320:SF289 RETINOL DEHYDROGENASE GH10714P-RELATED oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 terpenoid metabolic process#GO:0006721;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;biological regulation#GO:0065007;hormone metabolic process#GO:0042445 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0038139|UniProtKB=Q9VFW6 Q9VFW6 PK2-R2 PTHR24243:SF232 G-PROTEIN COUPLED RECEPTOR PYROKININ 2 RECEPTOR 1-RELATED neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0035179|UniProtKB=Q7KVC9 Q7KVC9 aln PTHR21093:SF2 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1C DROME|FlyBase=FBgn0053459|UniProtKB=A1ZAG9 A1ZAG9 HDC06756 PTHR24278:SF36 COAGULATION FACTOR PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine protease#PC00203 DROME|FlyBase=FBgn0039882|UniProtKB=Q9V9S9 Q9V9S9 Rift PTHR12929:SF10 SOLUTE CARRIER FAMILY 52 RIBOFLAVIN TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;transport#GO:0006810;establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0030485|UniProtKB=Q9VYD2 Q9VYD2 Dmel\CG1998 PTHR11863:SF241 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 oxidase#PC00175 DROME|FlyBase=FBgn0032516|UniProtKB=Q9VJY8 Q9VJY8 Ing5 PTHR10333:SF113 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 5 histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone H3 reader activity#GO:0140006;chromatin-protein adaptor activity#GO:0140463 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0035085|UniProtKB=Q9W0X9 Q9W0X9 CT12588 PTHR12489:SF19 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0015586|UniProtKB=Q9VVW1 Q9VVW1 Acp76A PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0032453|UniProtKB=Q9VK60 Q9VK60 Dmel\CG6180 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 DROME|FlyBase=FBgn0033912|UniProtKB=Q8T3U2 Q8T3U2 RpS23 PTHR11652:SF14 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 DROME|FlyBase=FBgn0035867|UniProtKB=Q9VSG9 Q9VSG9 Dmel\CG13671 PTHR46497:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 oxidoreductase#PC00176 DROME|FlyBase=FBgn0265174|UniProtKB=Q9V7W1 Q9V7W1 PIG-V PTHR12468:SF2 GPI MANNOSYLTRANSFERASE 2 GPI ALPHA-1,6-MANNOSYLTRANSFERASE 2 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247 transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;mannosyltransferase complex#GO:0031501;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0003356|UniProtKB=C0HKF7 C0HKF7 Jon99Cii PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0050275|UniProtKB=Q7KVK5 Q7KVK5 CG13520 PTHR21178:SF8 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 structural protein#PC00211 DROME|FlyBase=FBgn0010246|UniProtKB=Q23979 Q23979 Myo61F PTHR13140:SF679 MYOSIN UNCONVENTIONAL MYOSIN IC ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based movement#GO:0030048;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;cytoskeleton organization#GO:0007010;transport#GO:0006810;actin filament-based process#GO:0030029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0050468|UniProtKB=A1ZA16 A1ZA16 Ir52c PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0004465|UniProtKB=Q9V420 Q9V420 mPges2 PTHR12782:SF5 MICROSOMAL PROSTAGLANDIN E SYNTHASE-2 PROSTAGLANDIN E SYNTHASE 2 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;reductase#PC00198;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0036110|UniProtKB=Q9VTC8 Q9VTC8 Cpr67Fb PTHR10380:SF245 CUTICLE PROTEIN CUTICULAR PROTEIN 67FB extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0266848|UniProtKB=Q9VR53 Q9VR53 wap PTHR19919:SF0 WD REPEAT CONTAINING PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 7 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039217|UniProtKB=Q8IMV7 Q8IMV7 Dmel\CG13627 PTHR23210:SF26 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0050031|UniProtKB=C0HKA4 C0HKA4 CG30031 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036617|UniProtKB=Q9VV44 Q9VV44 Cpr72Ea PTHR10380:SF243 CUTICLE PROTEIN CUTICULAR PROTEIN 72EA extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0035704|UniProtKB=Q9VRX2 Q9VRX2 Vps8 PTHR12616:SF8 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;vesicle organization#GO:0016050;transport#GO:0006810 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0266673|UniProtKB=Q9XTM1 Q9XTM1 Sec10 PTHR12100:SF0 SEC10 EXOCYST COMPLEX COMPONENT 5 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;secretion by cell#GO:0032940;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179 vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocyst#GO:0000145;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0032864|UniProtKB=Q9VIM0 Q9VIM0 38C.55 PTHR11010:SF128 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 serine protease#PC00203 DROME|FlyBase=FBgn0034110|UniProtKB=A0A0B4KF86 A0A0B4KF86 Atg9 PTHR13038:SF10 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9 intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;reticulophagy#GO:0061709;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;cellular component organization#GO:0016043;localization#GO:0051179;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;autophagosome#GO:0005776 DROME|FlyBase=FBgn0035025|UniProtKB=Q9W148 Q9W148 uri PTHR15111:SF2 RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of apoptotic process#GO:0042981;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;negative regulation of programmed cell death#GO:0043069;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0286027|UniProtKB=Q9VJQ4 Q9VJQ4 Rnmt PTHR12189:SF2 MRNA GUANINE-7- METHYLTRANSFERASE MRNA CAP GUANINE-N(7) METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0033648|UniProtKB=A1Z8N9 A1Z8N9 Ir48b PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0032023|UniProtKB=Q9VLP0 Q9VLP0 witty PTHR33562:SF15 ATILLA, ISOFORM B-RELATED-RELATED ATILLA, ISOFORM B-RELATED DROME|FlyBase=FBgn0035696|UniProtKB=Q9VRW4 Q9VRW4 Best2 PTHR10736:SF11 BESTROPHIN BESTROPHIN 2 chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0283741|UniProtKB=C7LAE5 C7LAE5 prage PTHR12801:SF115 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED FI18136P1-RELATED nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>RNase H#P00538 DROME|FlyBase=FBgn0026396|UniProtKB=P81911 P81911 Or22c PTHR21137:SF26 ODORANT RECEPTOR ODORANT RECEPTOR 10A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0003747|UniProtKB=Q9W497 Q9W497 Gr5a PTHR21421:SF29 GUSTATORY RECEPTOR GUSTATORY RECEPTOR 5A FOR TREHALOSE-RELATED sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;system process#GO:0003008 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0038653|UniProtKB=A0A0B4KHD0 A0A0B4KHD0 Octalpha2R PTHR24248:SF174 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA2-ADRENERGIC-LIKE OCTOPAMINE RECEPTOR, ISOFORM B signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0041210|UniProtKB=M9PHQ2 M9PHQ2 HDAC4 PTHR10625:SF57 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824 cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0038747|UniProtKB=Q9VDS5 Q9VDS5 RhoGAP92B PTHR14130:SF14 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 92B enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589 negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of signal transduction#GO:0009968;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0022361|UniProtKB=Q9V4D9 Q9V4D9 Pur-alpha PTHR12611:SF0 PUR-TRANSCRIPTIONAL ACTIVATOR PURINE-RICH BINDING PROTEIN-ALPHA, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0052446|UniProtKB=M9PD88 M9PD88 Atox1 PTHR46365:SF1 COPPER TRANSPORT PROTEIN ATOX1 COPPER TRANSPORT PROTEIN ATOX1 molecular carrier activity#GO:0140104 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0034744|UniProtKB=Q9W236 Q9W236 Vps20 PTHR22761:SF5 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 6 intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;vesicle budding from membrane#GO:0006900;endosomal transport#GO:0016197;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nuclear membrane organization#GO:0071763;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;membrane assembly#GO:0071709;late endosome to vacuole transport#GO:0045324 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;nuclear envelope#GO:0005635 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0052669|UniProtKB=P83740 P83740 CG32669 PTHR42985:SF51 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER LD47995P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0039473|UniProtKB=Q9VB91 Q9VB91 Dmel\CG17191 PTHR11610:SF178 LIPASE FI01825P-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0011606|UniProtKB=Q9XZ29 Q9XZ29 Klp3A PTHR47969:SF15 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;microtubule motor activity#GO:0003777;cytoskeletal motor activity#GO:0003774 spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;microtubule cytoskeleton organization#GO:0000226 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0033166|UniProtKB=Q7JRJ1 Q7JRJ1 Eaf PTHR15970:SF2 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR EAF transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 DROME|Gene_ORFName=Dmel_CG46510|UniProtKB=A0ACD4DAV7 A0ACD4DAV7 CG46510 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0051810|UniProtKB=Q8SX47 Q8SX47 Dmel\CG31810 PTHR43899:SF9 RH59310P MIP25013P-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0032787|UniProtKB=Q9VIV9 Q9VIV9 Dmel\CG10195 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 ACYL-COENZYME A DIPHOSPHATASE NUDT19 DROME|FlyBase=FBgn0033315|UniProtKB=A1Z7G9 A1Z7G9 beta3GalTII PTHR11214:SF410 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 6 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0052204|UniProtKB=A0A6M3Q9R8 A0A6M3Q9R8 Dmel\CG32204 PTHR36694:SF10 PASIFLORA 1, ISOFORM A-RELATED MARVEL DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0033048|UniProtKB=Q8MS84 Q8MS84 Dmel\CG7881 PTHR11662:SF280 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0039640|UniProtKB=Q7KRW4 Q7KRW4 superdeath PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0036579|UniProtKB=Q961B9 Q961B9 Tmx3 PTHR46426:SF2 PROTEIN DISULFIDE-ISOMERASE TMX3 LD24073P cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072 DROME|FlyBase=FBgn0025674|UniProtKB=Q961D1 Q961D1 CycK PTHR10026:SF144 CYCLIN CYCLIN-K molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase activator activity#GO:0030295;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 transferase complex#GO:1990234;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 kinase modulator#PC00140;kinase activator#PC00138 Cell cycle#P00013>CdkC#P00489 DROME|FlyBase=FBgn0029766|UniProtKB=Q9W4C1 Q9W4C1 Dmel\CG15784 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 DROME|FlyBase=FBgn0034301|UniProtKB=A1ZB32 A1ZB32 Dmel\CG5756 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0260745|UniProtKB=Q86B94 Q86B94 mfas PTHR10900:SF77 PERIOSTIN-RELATED FI19380P1 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0031979|UniProtKB=Q9VLT8 Q9VLT8 CCDC53 PTHR13015:SF0 PROTEIN AD-016-RELATED WASH COMPLEX SUBUNIT 3 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;export from cell#GO:0140352;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;transport#GO:0006810;exocytosis#GO:0006887;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0053138|UniProtKB=A1Z992 A1Z992 Agbe PTHR43651:SF15 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;glycogen biosynthetic process#GO:0005978;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 amylase#PC00048 DROME|FlyBase=FBgn0086657|UniProtKB=Q9V3Y8 Q9V3Y8 IKKepsilon PTHR22969:SF15 IKB KINASE FI05319P protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of response to external stimulus#GO:0032103;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;positive regulation of biosynthetic process#GO:0009891;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of type I interferon production#GO:0032481;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;activation of innate immune response#GO:0002218 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0033943|UniProtKB=A0A6M3QH83 A0A6M3QH83 Dmel\CG12869 PTHR11559:SF377 CARBOXYLESTERASE CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN esterase#PC00097 DROME|FlyBase=FBgn0033184|UniProtKB=Q7K3V6 Q7K3V6 mEFTu2 PTHR43721:SF2 ELONGATION FACTOR TU-RELATED ELONGATION FACTOR TU, MITOCHONDRIAL translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 translation elongation factor#PC00222 DROME|FlyBase=FBgn0042187|UniProtKB=Q9VQ99 Q9VQ99 SP113 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0020294|UniProtKB=Q9VP79 Q9VP79 ko PTHR22437:SF0 WINGED HELIX DOMAIN-CONTAINING PROTEIN FI21431P1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0259187|UniProtKB=B7YZQ6 B7YZQ6 Ir60d PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0036317|UniProtKB=Q9VU18 Q9VU18 CT30663 PTHR16001:SF4 ANGEL WING family ECTO-NOX DISULFIDE-THIOL EXCHANGER 1-RELATED oxidoreductase#PC00176 DROME|FlyBase=FBgn0259204|UniProtKB=B7Z0X7 B7Z0X7 sloth2 PTHR28492:SF1 HYPOTHETICAL PROTEIN LOC691921 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 6 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0029778|UniProtKB=Q9W4A9 Q9W4A9 RhoGAP5A PTHR46075:SF2 CHIMERIN FAMILY MEMBER RHO GTPASE ACTIVATING PROTEIN AT 5A, ISOFORM A enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 DROME|FlyBase=FBgn0028879|UniProtKB=Q9V416 Q9V416 wwk PTHR12308:SF51 ANOCTAMIN ANOCTAMIN-8 intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0028648|UniProtKB=Q9V3E3 Q9V3E3 mRpL50 PTHR31542:SF1 39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML50 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0051286|UniProtKB=Q8INR8 Q8INR8 NEST:bs36b12 PTHR10334:SF565 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0035199|UniProtKB=Q8IRH8 Q8IRH8 tfc PTHR22802:SF456 C-TYPE LECTIN SUPERFAMILY MEMBER AT17652P-RELATED pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0013756|UniProtKB=A1Z8P9 A1Z8P9 Mgtor PTHR18898:SF8 NUCLEOPROTEIN TPR-RELATED NUCLEOPROTEIN TPR structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;regulation of cell cycle process#GO:0010564;regulation of microtubule cytoskeleton organization#GO:0070507;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;regulation of mitotic spindle assembly#GO:1901673;metabolic process#GO:0008152;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;regulation of cytoskeleton organization#GO:0051493;regulation of spindle organization#GO:0090224;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of organelle assembly#GO:1902115;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0034661|UniProtKB=Q9W2C8 Q9W2C8 tpr PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0031424|UniProtKB=Q9VQC0 Q9VQC0 VGlut1 PTHR11662:SF456 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER, ISOFORM A carboxylic acid transmembrane transporter activity#GO:0046943;L-amino acid transmembrane transporter activity#GO:0015179;acidic amino acid transmembrane transporter activity#GO:0015172;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter transport#GO:0006836;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport#GO:0016192;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;cell communication#GO:0007154;localization#GO:0051179;regulation of synapse structure or activity#GO:0050803;cellular localization#GO:0051641 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;presynapse#GO:0098793;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0032698|UniProtKB=Q8INX3 Q8INX3 CG10336 PTHR13220:SF11 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;DNA-templated DNA replication#GO:0006261;regulation of DNA replication#GO:0006275;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;regulation of DNA-templated DNA replication#GO:0090329;DNA replication#GO:0006260;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;DNA damage response#GO:0006974;negative regulation of DNA-templated DNA replication#GO:2000104;DNA metabolic process#GO:0006259;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of DNA metabolic process#GO:0051053;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0038714|UniProtKB=Q4V480 Q4V480 Cpr92A PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0010228|UniProtKB=Q06943 Q06943 HmgZ PTHR48112:SF20 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN D-RELATED cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 DROME|FlyBase=FBgn0031081|UniProtKB=Q9W5Y0 Q9W5Y0 Nep3 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 DROME|FlyBase=FBgn0039594|UniProtKB=Q9VAU1 Q9VAU1 snu PTHR43038:SF3 ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 ABC TRANSPORTER G FAMILY MEMBER 23 ISOFORM X1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0261987|UniProtKB=Q9VEG6 Q9VEG6 Pxt PTHR11475:SF148 OXIDASE/PEROXIDASE CHORION PEROXIDASE antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 DROME|FlyBase=FBgn0028436|UniProtKB=Q9U6M0 Q9U6M0 ECSIT PTHR13113:SF1 ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;toll-like receptor 4 signaling pathway#GO:0034142;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>ECSIT#P01349 DROME|FlyBase=FBgn0261611|UniProtKB=A0A0B4LF70 A0A0B4LF70 ORE-16 PTHR22198:SF1 FERM DOMAIN-CONTAINING PROTEIN DUF7153 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0033605|UniProtKB=A1Z8I0 A1Z8I0 Dmel\CG9067 PTHR12403:SF11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0035575|UniProtKB=Q9VZ84 Q9VZ84 Dmel\CG7509 PTHR24373:SF385 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN GH01279P-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0033789|UniProtKB=A1Z979 A1Z979 Dmel\CG13324 PTHR37685:SF1 GEO11136P1-RELATED GEO11136P1-RELATED DROME|FlyBase=FBgn0037342|UniProtKB=Q9VND7 Q9VND7 Dmel\CG2931 PTHR24012:SF897 RNA BINDING PROTEIN RNA-BINDING PROTEIN 42 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031372|UniProtKB=Q9VQ51 Q9VQ51 Dmel\CG7295 PTHR10281:SF76 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED CALCUTTA CUP-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0010019|UniProtKB=Q9V3S0 Q9V3S0 Cyp4g1 PTHR24291:SF106 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4G1-RELATED metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0263234|UniProtKB=Q9VKA9 Q9VKA9 Phae1 PTHR24276:SF99 POLYSERASE-RELATED AT26814P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0085224|UniProtKB=A1ZAY5 A1ZAY5 Dmel\CG34195 PTHR22809:SF5 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL6 methyltransferase#PC00155 DROME|FlyBase=FBgn0263740|UniProtKB=Q24208 Q24208 eIF2gamma PTHR42854:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 DROME|FlyBase=FBgn0032030|UniProtKB=Q9VLN1 Q9VLN1 Wdr82 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 binding#GO:0005488;chromatin binding#GO:0003682 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 DROME|FlyBase=FBgn0039543|UniProtKB=Q9VB02 Q9VB02 CROT PTHR22589:SF67 CARNITINE O-ACYLTRANSFERASE PEROXISOMAL CARNITINE O-OCTANOYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0035969|UniProtKB=Q9VSV2 Q9VSV2 DmNAT3 PTHR11616:SF339 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293 establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;monoatomic cation transport#GO:0006812;localization#GO:0051179;glycine transport#GO:0015816;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 DROME|FlyBase=FBgn0032160|UniProtKB=Q9VL68 Q9VL68 Dmel\CG4598 PTHR11941:SF45 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;lyase#PC00144;hydratase#PC00120 DROME|FlyBase=FBgn0034982|UniProtKB=Q9W1A2 Q9W1A2 Naa35 PTHR21373:SF1 GLUCOSE REPRESSIBLE PROTEIN MAK10 N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 acetyltransferase#PC00038 DROME|FlyBase=FBgn0052603|UniProtKB=Q8IR57 Q8IR57 Dmel\CG32603 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0038224|UniProtKB=O77134 O77134 ATPsynE PTHR12427:SF1 ATP SYNTHASE E CHAIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT E, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;oxidative phosphorylation#GO:0006119;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390 mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;transporter complex#GO:1990351 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0260477|UniProtKB=Q9W2G1 Q9W2G1 SP37 PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0259223|UniProtKB=B7Z103 B7Z103 CG15055 PTHR39068:SF4 LARVAL/PUPAL CUTICLE PROTEIN H1C-LIKE PROTEIN-RELATED SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0033542|UniProtKB=Q8MS78 Q8MS78 CAH13 PTHR18952:SF227 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 13-RELATED hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0036784|UniProtKB=Q9VVP4 Q9VVP4 Tktl PTHR43195:SF1 TRANSKETOLASE TRANSKETOLASE small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;transketolase activity#GO:0004802;transketolase or transaldolase activity#GO:0016744;catalytic activity#GO:0003824;transferase activity#GO:0016740;heterocyclic compound binding#GO:1901363 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transketolase#PC00221;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0029752|UniProtKB=Q8IFW4 Q8IFW4 TrxT PTHR10438:SF475 THIOREDOXIN THIOREDOXIN disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 DROME|FlyBase=FBgn0030899|UniProtKB=Q9VWX7 Q9VWX7 Hesr PTHR10985:SF145 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HES-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 DROME|FlyBase=FBgn0013771|UniProtKB=Q27594 Q27594 Cyp6a9 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0037399|UniProtKB=Q9VNK9 Q9VNK9 Or83c PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0036793|UniProtKB=Q9VVQ4 Q9VVQ4 Dmel\CG4174 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0051229|UniProtKB=Q8IN78 Q8IN78 Tim22 PTHR14110:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;mitochondrial protein import pathway#GO:7770058 intracellular organelle#GO:0043229;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 DROME|FlyBase=FBgn0027330|UniProtKB=Q9W3C1 Q9W3C1 l(1)G0020 PTHR10925:SF5 N-ACETYLTRANSFERASE 10 RNA CYTIDINE ACETYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101 ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;ribonucleoprotein complex biogenesis#GO:0022613;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684 RNA processing factor#PC00147 DROME|FlyBase=FBgn0033206|UniProtKB=Q7K130 Q7K130 DCTN4-p62 PTHR13034:SF2 DYNACTIN P62 SUBUNIT DYNACTIN SUBUNIT 4 intracellular transport#GO:0046907;transport#GO:0006810;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629 microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0260644|UniProtKB=E1JIB0 E1JIB0 Dmel\CG42536 PTHR36694:SF14 PASIFLORA 1, ISOFORM A-RELATED LP21121P DROME|FlyBase=FBgn0033658|UniProtKB=A1Z8Q0 A1Z8Q0 Twdlbeta PTHR31927:SF13 FI07246P-RELATED-RELATED TWEEDLEBETA structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 DROME|FlyBase=FBgn0284248|UniProtKB=P84029 P84029 Cyt-c-p PTHR11961:SF56 CYTOCHROME C CYTOCHROME C cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 DROME|FlyBase=FBgn0028647|UniProtKB=Q9VBR8 Q9VBR8 anon-96CDa PTHR24390:SF211 ZINC FINGER PROTEIN ZINC FINGER PROTEIN XFIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0034846|UniProtKB=Q7KVJ1 Q7KVJ1 BcDNA:AT26616 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0035211|UniProtKB=Q8MSC8 Q8MSC8 anon-WO0118547.230 PTHR12480:SF13 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD LD14533P dioxygenase activity#GO:0051213;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;sequence-specific DNA binding#GO:0043565;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 positive regulation of cellular component organization#GO:0051130;positive regulation of protein metabolic process#GO:0051247;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of translation#GO:0045727;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein-containing complex disassembly#GO:0043244;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0032538|UniProtKB=Q8SZM2 Q8SZM2 Vajk2 PTHR47771:SF12 LD27203P-RELATED HL02234P-RELATED DROME|FlyBase=FBgn0044823|UniProtKB=Q9VNE7 Q9VNE7 Spec2 PTHR13502:SF6 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN HOMOLOG plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0052296|UniProtKB=B7Z043 B7Z043 Mrtf PTHR22793:SF12 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0003942|UniProtKB=P15357 P15357 RpS27A PTHR10666:SF437 UBIQUITIN POLYUBIQUITIN-B structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ribosome#GO:0005840;nucleus#GO:0005634;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0019972|UniProtKB=O01382 O01382 Drice PTHR10454:SF253 CASPASE CASPASE DRICE-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;positive regulation of apoptotic process#GO:0043065;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;programmed cell death#GO:0012501;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0001108|UniProtKB=P13496 P13496 DCTN1-p150 PTHR18916:SF91 DYNACTIN 1-RELATED MICROTUBULE-BINDING DYNACTIN SUBUNIT 1 organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;microtubule cytoskeleton organization#GO:0000226;spindle localization#GO:0051653;cellular localization#GO:0051641;localization#GO:0051179;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010;nuclear migration#GO:0007097;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;mitotic cell cycle process#GO:1903047;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010 chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;axon#GO:0030424;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 chaperone#PC00072 Huntington disease#P00029>Dynactin#P00781 DROME|FlyBase=FBgn0026061|UniProtKB=Q9VV72 Q9VV72 Mipp1 PTHR20963:SF58 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0260444|UniProtKB=Q9V3G6 Q9V3G6 Not10 PTHR12979:SF5 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of protein metabolic process#GO:0051248;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 CCR4-NOT complex#GO:0030014;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0026380|UniProtKB=Q9XYN7 Q9XYN7 Prosbeta3 PTHR11599:SF62 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-3 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0051225|UniProtKB=Q8IMY8 Q8IMY8 Ir94f PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0025519|UniProtKB=A1ZAC7 A1ZAC7 fidipidine PTHR16441:SF10 FIDIPIDINE COILED-COIL DOMAIN-CONTAINING PROTEIN 93 vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0033911|UniProtKB=A1Z9M6 A1Z9M6 VGAT PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER glycine transmembrane transporter activity#GO:0015187;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;neutral amino acid transport#GO:0015804;cellular localization#GO:0051641;glycine transport#GO:0015816;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;synaptic vesicle cycle#GO:0099504;organic acid transport#GO:0015849;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;dendrite#GO:0030425;dendritic tree#GO:0097447;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;somatodendritic compartment#GO:0036477;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0250907|UniProtKB=Q9W5U2 Q9W5U2 Cht10 PTHR11177:SF359 CHITINASE CHITINASE 10-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824 chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0015270|UniProtKB=Q24168 Q24168 Orc2 PTHR14052:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 DNA replication origin binding#GO:0003688;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;nuclear origin of replication recognition complex#GO:0005664;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974 replication origin binding protein#PC00199 DROME|FlyBase=FBgn0259927|UniProtKB=M9PHI8 M9PHI8 CG32543 PTHR45746:SF5 LP21163P REGULATOR OF G-PROTEIN SIGNALING 7 enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0050011|UniProtKB=A1Z851 A1Z851 gem PTHR11037:SF21 TRANSCRIPTION FACTOR CP2 GEMINI, ISOFORM C sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0250746|UniProtKB=Q9VNA5 Q9VNA5 Prosbeta7 PTHR11599:SF5 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-4 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0261722|UniProtKB=Q95T12 Q95T12 fwe PTHR13314:SF2 CALCIUM CHANNEL FLOWER HOMOLOG CALCIUM CHANNEL FLOWER HOMOLOG calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;endocytosis#GO:0006897;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;synaptic vesicle endocytosis#GO:0048488;transmembrane transport#GO:0055085;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular vesicle#GO:0097708 DROME|FlyBase=FBgn0058006|UniProtKB=Q8SYC3 Q8SYC3 BcDNA:RE68569 PTHR11923:SF67 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 RE68569P cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0033874|UniProtKB=Q7K0S6 Q7K0S6 CtsL2 PTHR12411:SF1051 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN F catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0286723|UniProtKB=Q9V3U0 Q9V3U0 hll PTHR24096:SF391 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE HEIMDALL-RELATED ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 DROME|FlyBase=FBgn0030824|UniProtKB=Q9VX73 Q9VX73 Dmel\CG5070 PTHR35905:SF1 PROTEIN, PUTATIVE-RELATED PROTEIN, PUTATIVE-RELATED DROME|FlyBase=FBgn0033994|UniProtKB=Q7K3B9 Q7K3B9 CG7544 PTHR13393:SF0 SAM-DEPENDENT METHYLTRANSFERASE RNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL16 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;post-transcriptional regulation of gene expression#GO:0010608;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;mRNA processing#GO:0006397;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0020912|UniProtKB=O18400 O18400 Ptx1 PTHR45882:SF3 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX HOMOLOG PTX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0261555|UniProtKB=Q8SXX4 Q8SXX4 CG42673 PTHR11232:SF17 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CAPON-LIKE PROTEIN signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 contractile muscle fiber#GO:0043292;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;axon#GO:0030424;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039776|UniProtKB=Q9VA69 Q9VA69 PH4alphaEFB PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033693|UniProtKB=A1Z8U7 A1Z8U7 CG33154 PTHR28532:SF1 GEO13458P1 LTO1 MATURATION FACTOR OF ABCE1 DROME|FlyBase=FBgn0020880|UniProtKB=Q9VLX5 Q9VLX5 Dmel\CG7179 PTHR24255:SF31 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED CUB DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0085459|UniProtKB=A8DY63 A8DY63 CG14766 PTHR23291:SF50 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0038830|UniProtKB=Q9VDI3 Q9VDI3 Dmel\CG17272 PTHR23050:SF348 CALCIUM BINDING PROTEIN MYOSIN-2 ESSENTIAL LIGHT CHAIN molecular function regulator activity#GO:0098772;cation binding#GO:0043169;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 DROME|FlyBase=FBgn0038211|UniProtKB=Q9VFM0 Q9VFM0 SP55 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED DROME|FlyBase=FBgn0050357|UniProtKB=A1Z7I5 A1Z7I5 Dmel\CG30357 PTHR22667:SF0 AT01380P-RELATED AT01380P-RELATED DROME|FlyBase=FBgn0003371|UniProtKB=P18431 P18431 sgg PTHR24057:SF82 GLYCOGEN SYNTHASE KINASE-3 ALPHA PROTEIN KINASE SHAGGY-RELATED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of signal transduction#GO:0009968;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;cell communication#GO:0007154;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of microtubule-based process#GO:0032886;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;regulation of catabolic process#GO:0009894;cellular developmental process#GO:0048869;positive regulation of catabolic process#GO:0009896;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PDGF signaling pathway#P00047>GSK3#P01153;Angiogenesis#P00005>GSK3beta#P00211;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175 DROME|FlyBase=FBgn0032346|UniProtKB=Q9VKJ4 Q9VKJ4 Csl4 PTHR12686:SF8 3'-5' EXORIBONUCLEASE CSL4-RELATED EXOSOME COMPLEX COMPONENT CSL4 rRNA processing#GO:0006364;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;maturation of 5.8S rRNA#GO:0000460;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 exoribonuclease#PC00099;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0085599|UniProtKB=A8Y548 A8Y548 Dmel\CG41284 PTHR21113:SF4 AGAP001705-PA CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0025641|UniProtKB=M9MSM5 M9MSM5 DAAM PTHR45725:SF22 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0264494|UniProtKB=Q8T9E6 Q8T9E6 ABCG1 PTHR48041:SF61 ABC TRANSPORTER G FAMILY MEMBER 28 SD03967P ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0037163|UniProtKB=Q9VNU2 Q9VNU2 laza PTHR10165:SF103 LIPID PHOSPHATE PHOSPHATASE FI04477P-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;dephosphorylation#GO:0016311;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0039487|UniProtKB=Q9VB75 Q9VB75 gb PTHR11785:SF535 AMINO ACID TRANSPORTER GH08870P L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0031657|UniProtKB=Q9VMX3 Q9VMX3 Polr1C PTHR11800:SF13 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0027529|UniProtKB=Q0E910 Q0E910 tapas PTHR22948:SF84 TUDOR DOMAIN CONTAINING PROTEIN FI02030P-RELATED RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;cell differentiation#GO:0030154;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anterior/posterior axis specification#GO:0009948;metabolic process#GO:0008152;anterior/posterior pattern specification#GO:0009952;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;oogenesis#GO:0048477;embryo development#GO:0009790;embryonic pattern specification#GO:0009880;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;macromolecule metabolic process#GO:0043170;cell maturation#GO:0048469;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;regionalization#GO:0003002;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036997|UniProtKB=Q9VPE8 Q9VPE8 Tdh PTHR42687:SF1 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0013672|UniProtKB=P00850 P00850 mt:ATPase6 PTHR11410:SF0 ATP SYNTHASE SUBUNIT A ATP SYNTHASE F(0) COMPLEX SUBUNIT A channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803 carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144 respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 primary active transporter#PC00068;ATP synthase#PC00002 ATP synthesis#P02721>ATP synthetase F0#P02797 DROME|FlyBase=FBgn0024196|UniProtKB=Q7KMS3 Q7KMS3 robl PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dynein complex#GO:0030286;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0035508|UniProtKB=Q9VZG4 Q9VZG4 Dmel\CG15005 PTHR22949:SF0 WHITE COLLAR 2 PROTEIN WC2 RE27538P DROME|FlyBase=FBgn0035511|UniProtKB=Q9VZG1 Q9VZG1 Cpr64Ab PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0010453|UniProtKB=P40589 P40589 Wnt4 PTHR12027:SF70 WNT RELATED PROTEIN WNT-16 cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 DROME|FlyBase=FBgn0000711|UniProtKB=P48462 P48462 flw PTHR11668:SF530 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Y-RELATED catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 DROME|FlyBase=FBgn0050157|UniProtKB=Q4V6M7 Q4V6M7 Ufsp1 PTHR48153:SF3 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 1 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 DROME|FlyBase=FBgn0037679|UniProtKB=Q9VHF6 Q9VHF6 Aduk PTHR24348:SF65 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK3 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 response to nutrient levels#GO:0031667;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;reticulophagy#GO:0061709;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component assembly#GO:0022607;biological regulation#GO:0065007;macroautophagy#GO:0016236;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;regulation of catabolic process#GO:0009894;autophagosome assembly#GO:0000045;response to starvation#GO:0042594;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;piecemeal microautophagy of the nucleus#GO:0034727;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919 autophagosome#GO:0005776;intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0035383|UniProtKB=Q9VZW7 Q9VZW7 CPT2 PTHR22589:SF16 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0029962|UniProtKB=Q9W3P7 Q9W3P7 CARPA PTHR18952:SF228 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN A, ISOFORM B metabolite interconversion enzyme#PC00262;dehydratase#PC00091 DROME|FlyBase=FBgn0037549|UniProtKB=Q7K4L8 Q7K4L8 Dmel\CG7878 PTHR47958:SF195 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA helicase#PC00032 DROME|FlyBase=FBgn0031601|UniProtKB=Q8SZ87 Q8SZ87 Dim1 PTHR12052:SF5 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4A RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 DROME|FlyBase=FBgn0039272|UniProtKB=A0A4D6K1E7 A0A4D6K1E7 Dmel\CG11836 PTHR24256:SF451 TRYPTASE-RELATED SERINE PROTEASE P12 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0035552|UniProtKB=Q9VZB3 Q9VZB3 Dmel\CG11350 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0042104|UniProtKB=Q9I7L1 Q9I7L1 Dmel\CG18747 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0034324|UniProtKB=A1ZB56 A1ZB56 Dmel\CG18538 PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0024558|UniProtKB=Q8IN02 Q8IN02 Dph5 PTHR10882:SF0 DIPHTHINE SYNTHASE DIPHTHINE METHYL ESTER SYNTHASE methyltransferase#PC00155 DROME|FlyBase=FBgn0030844|UniProtKB=A8JV41 A8JV41 ppk23 PTHR11690:SF247 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 23, ISOFORM C gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0010263|UniProtKB=M9PBZ2 M9PBZ2 Rbp9 PTHR10352:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G FOUND IN NEURONS, ISOFORM K-RELATED cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 DROME|FlyBase=FBgn0031721|UniProtKB=Q9VMP5 Q9VMP5 Dmel\CG14017 PTHR33588:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 structural protein#PC00211 DROME|FlyBase=FBgn0011236|UniProtKB=O77459 O77459 ken PTHR45993:SF7 B-CELL LYMPHOMA/LEUKEMIA 11 TRANSCRIPTION FACTOR KEN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0038686|UniProtKB=A0A0B4KHR2 A0A0B4KHR2 Dmel\CG5555 PTHR24007:SF7 BRCA1-ASSOCIATED PROTEIN BRCA1-ASSOCIATED PROTEIN ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 signal transduction#GO:0007165;cellular process#GO:0009987;small GTPase-mediated signal transduction#GO:0007264;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;protein modification by small protein conjugation or removal#GO:0070647;cell communication#GO:0007154;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0040064|UniProtKB=Q9VL70 Q9VL70 Acaa PTHR18919:SF175 ACETYL-COA C-ACYLTRANSFERASE 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0051262|UniProtKB=Q8IN99 Q8IN99 Dmel\CG31262 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 sodium ion transport#GO:0006814;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0035588|UniProtKB=Q9VRJ4 Q9VRJ4 Dhrs4 PTHR43943:SF19 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE_REDUCTASE 4 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 DROME|FlyBase=FBgn0024352|UniProtKB=Q9VPN5 Q9VPN5 Stip1 PTHR22904:SF523 TPR REPEAT CONTAINING PROTEIN STRESS-INDUCED-PHOSPHOPROTEIN 1 protein binding#GO:0005515;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488 DROME|FlyBase=FBgn0039321|UniProtKB=Q9VBS7 Q9VBS7 Dmel\CG10550 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0032973|UniProtKB=Q9V9P0 Q9V9P0 Dmel\CG6675 PTHR11610:SF192 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0003339|UniProtKB=P09077 P09077 Scr PTHR45771:SF6 HOMEOTIC PROTEIN DEFORMED HOMEOTIC PROTEIN SEX COMBS REDUCED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regionalization#GO:0003002;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;pattern specification process#GO:0007389;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0020255|UniProtKB=Q9VZ23 Q9VZ23 Ran PTHR24071:SF0 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;organelle localization#GO:0051640;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;gene expression#GO:0010467;protein export from nucleus#GO:0006611;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;protein transport#GO:0015031;protein import into nucleus#GO:0006606 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 small GTPase#PC00208 DROME|FlyBase=FBgn0039024|UniProtKB=Q9VCU1 Q9VCU1 Nepl15 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0035799|UniProtKB=Q9VS90 Q9VS90 mmm PTHR12442:SF5 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 3 binding#GO:0005488;protein binding#GO:0005515 cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;inner dynein arm assembly#GO:0036159;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;inner dynein arm#GO:0036156;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0027081|UniProtKB=Q9VKB0 Q9VKB0 ThrRS PTHR11451:SF46 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0010222|UniProtKB=Q04448 Q04448 Nmdmc PTHR48099:SF11 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 DROME|FlyBase=FBgn0038488|UniProtKB=Q9I7J2 Q9I7J2 m-cup PTHR24173:SF82 ANKYRIN REPEAT CONTAINING FI19351P1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031018|UniProtKB=Q9VWI4 Q9VWI4 narya PTHR22663:SF17 RING FINGER PROTEIN NARYA-RELATED RING FINGER PROTEIN NARYA-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 homologous chromosome pairing at meiosis#GO:0007129;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982 membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233 DROME|FlyBase=FBgn0031378|UniProtKB=Q9VQ59 Q9VQ59 Dmel\CG15362 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 DROME|FlyBase=FBgn0042206|UniProtKB=Q9VGA1 Q9VGA1 GstD10 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0026411|UniProtKB=Q9V472 Q9V472 Lim1 PTHR24208:SF105 LIM/HOMEOBOX PROTEIN LHX DLIM1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0051300|UniProtKB=Q8IMT6 Q8IMT6 CG13657 PTHR11012:SF12 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0040372|UniProtKB=M9PGH7 M9PGH7 G9a PTHR46307:SF5 G9A, ISOFORM B G9A, ISOFORM B intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0041102|UniProtKB=Q9Y170 Q9Y170 ocn PTHR12258:SF5 JANUS-A/JANUS-B SEX-REGULATED PROTEIN JANUS-A-RELATED catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DROME|FlyBase=FBgn0033932|UniProtKB=A1Z9Q8 A1Z9Q8 Dh44-R1 PTHR45620:SF15 PDF RECEPTOR-LIKE PROTEIN-RELATED DIURETIC HORMONE RECEPTOR hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0051956|UniProtKB=Q8IA42 Q8IA42 Pgant4 PTHR11675:SF134 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0026751|UniProtKB=Q9Y095 Q9Y095 XRCC1 PTHR11370:SF6 DNA-REPAIR PROTEIN XRCC1 DNA REPAIR PROTEIN XRCC1 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;base-excision repair#GO:0006284;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0005390|UniProtKB=Q9W451 Q9W451 fs(1)M3 PTHR22918:SF6 SEMINAL PLASMA PROTEIN EG:8D8.1 PROTEIN-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0034218|UniProtKB=Q8SZN4 Q8SZN4 Dmel\CG18467 PTHR12864:SF85 RAN BINDING PROTEIN 9-RELATED GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0050429|UniProtKB=Q8MLN3 Q8MLN3 Dmel\CG30429 PTHR46511:SF1 MORN REPEAT-CONTAINING PROTEIN 3 MORN REPEAT-CONTAINING PROTEIN 3 DROME|FlyBase=FBgn0039064|UniProtKB=Q0KI25 Q0KI25 Dmel\CG4467 PTHR11533:SF304 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824 catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0004367|UniProtKB=Q9VXG8 Q9VXG8 mei-41 PTHR11139:SF133 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE ATR transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;telomere organization#GO:0032200;cell communication#GO:0007154;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;DNA integrity checkpoint signaling#GO:0031570;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cellular response to stress#GO:0033554;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;organelle organization#GO:0006996;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway#P00059>ATM/ATR#P01481;p53 pathway feedback loops 2#P04398>ATM#P04669 DROME|FlyBase=FBgn0036279|UniProtKB=M9PI37 M9PI37 Ncc69 PTHR11827:SF103 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SODIUM CHLORIDE COTRANSPORTER 69, ISOFORM E symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0026666|UniProtKB=Q8T3X9 Q8T3X9 MagR PTHR10072:SF41 IRON-SULFUR CLUSTER ASSEMBLY PROTEIN IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 DROME|FlyBase=FBgn0053696|UniProtKB=Q9VT27 Q9VT27 CNMaR PTHR46641:SF25 FMRFAMIDE RECEPTOR-RELATED CNMAMIDE RECEPTOR-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0029944|UniProtKB=Q9W3R6 Q9W3R6 Dok PTHR21258:SF62 DOCKING PROTEIN RELATED DOWNSTREAM OF KINASE regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0265968|UniProtKB=B7Z018 B7Z018 Tfb5 PTHR28580:SF1 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;protein-DNA complex assembly#GO:0065004;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;protein-containing complex assembly#GO:0065003 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0027493|UniProtKB=Q9Y0Y2 Q9Y0Y2 Adss PTHR11846:SF0 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 DROME|FlyBase=FBgn0030016|UniProtKB=Q9W3I5 Q9W3I5 Or7a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030434|UniProtKB=Q9VYI2 Q9VYI2 Brms1 PTHR21964:SF13 BREAST CANCER METASTASIS-SUPPRESSOR 1 BRMS1 TRANSCRIPTIONAL REPRESSOR protein binding#GO:0005515;histone deacetylase binding#GO:0042826;enzyme binding#GO:0019899;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0015838|UniProtKB=A0A0B4KEN4 A0A0B4KEN4 Vang PTHR20886:SF11 VANG-LIKE PROTEIN VANG-LIKE PROTEIN cell communication#GO:0007154;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;epithelium development#GO:0060429;tissue development#GO:0009888;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0032131|UniProtKB=Q9VLA4 Q9VLA4 Dmel\CG3841 PTHR43142:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121 DROME|FlyBase=FBgn0053260|UniProtKB=Q0E8E7 Q0E8E7 Tsen34 PTHR13070:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34 endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0041627|UniProtKB=Q9I7M8 Q9I7M8 Ku80 PTHR12604:SF4 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU80 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;telomeric repeat DNA binding#GO:0042162 cellular response to stress#GO:0033554;telomere organization#GO:0032200;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA helicase#PC00011 DROME|FlyBase=FBgn0030539|UniProtKB=Q9VY62 Q9VY62 Dmel\CG1368 PTHR15363:SF4 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 CUTICLE PROTEIN 16.5-RELATED transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0035356|UniProtKB=Q9VZZ5 Q9VZZ5 Dmel\CG16986 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 DROME|FlyBase=FBgn0000588|UniProtKB=Q24338 Q24338 esc PTHR10253:SF12 POLYCOMB PROTEIN POLYCOMB PROTEIN EED molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleosome binding#GO:0031491;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0039150|UniProtKB=Q9VCD3 Q9VCD3 Dmel\CG13605 PTHR15860:SF0 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN LP20373P ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0036801|UniProtKB=Q8SY34 Q8SY34 MYPT-75D PTHR24179:SF29 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 LD46604P protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 DROME|FlyBase=FBgn0044826|UniProtKB=A0A0B4KGS4 A0A0B4KGS4 Pak3 PTHR48015:SF22 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;regulation of MAPK cascade#GO:0043408;response to stress#GO:0006950;response to nutrient levels#GO:0031667;cellular process#GO:0009987;signal transduction#GO:0007165;cell migration#GO:0016477;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Ras Pathway#P04393>PAK#P04553;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;T cell activation#P00053>PAK#P01319;Angiogenesis#P00005>PAK#P00249 DROME|FlyBase=FBgn0038902|UniProtKB=Q9VD82 Q9VD82 Dmel\CG6800 PTHR24056:SF171 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 20 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0029175|UniProtKB=Q9Y169 Q9Y169 sotv PTHR11062:SF381 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-2 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0040666|UniProtKB=Q9W114 Q9W114 Dmel\CG12848 PTHR31278:SF2 CHCHD1 SMALL RIBOSOMAL SUBUNIT PROTEIN MS37 DROME|FlyBase=FBgn0051019|UniProtKB=Q8IMH9 Q8IMH9 Dmel\CG31019 PTHR12756:SF9 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 6 metallopeptidase activity#GO:0008237;binding#GO:0005488;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;protein binding#GO:0005515;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metalloprotease#PC00153 DROME|FlyBase=FBgn0039406|UniProtKB=Q9VBH8 Q9VBH8 RpL34a PTHR10759:SF0 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 DROME|FlyBase=FBgn0038702|UniProtKB=Q9VDX5 Q9VDX5 Dmel\CG3739 PTHR11010:SF5 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED RE36938P-RELATED serine protease#PC00203 DROME|FlyBase=FBgn0031220|UniProtKB=Q9VPJ7 Q9VPJ7 Dmel\CG4822 PTHR48041:SF15 ABC TRANSPORTER G FAMILY MEMBER 28 FI05267P primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0036552|UniProtKB=Q9VUW3 Q9VUW3 IMP PTHR20854:SF25 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 biological regulation#GO:0065007;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 DROME|FlyBase=FBgn0034951|UniProtKB=A0A0B4LGH8 A0A0B4LGH8 Dmel\CG3860 PTHR10972:SF136 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN lipid binding#GO:0008289;steroid binding#GO:0005496;binding#GO:0005488;sterol binding#GO:0032934 cytosol#GO:0005829;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0001104|UniProtKB=P20353 P20353 Galphai PTHR10218:SF227 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA I SUBUNIT hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117;G-protein#PC00020 Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Opioid prodynorphin pathway#P05916>G-protein#P06002;PI3 kinase pathway#P00048>Galpha#P01199;Enkephalin release#P05913>G-Protein (i)#P05974 DROME|FlyBase=FBgn0050069|UniProtKB=A1Z9M5 A1Z9M5 Sdb PTHR31516:SF16 STABILIZER OF AXONEMAL MICROTUBULES 2 SAXO DOWNSTREAM OF BLISTERED binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule#GO:0005874;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoplasmic microtubule#GO:0005881;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0025186|UniProtKB=O76924 O76924 ari-2 PTHR11685:SF210 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH2 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0037020|UniProtKB=Q9VPB8 Q9VPB8 Pex14 PTHR23058:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX14 PEROXISOMAL MEMBRANE PROTEIN PEX14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;peroxisome organization#GO:0007031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;peroxisomal transport#GO:0043574;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558 transporter complex#GO:1990351;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0030507|UniProtKB=Q9VYA4 Q9VYA4 Dmel\CG11164 PTHR13383:SF11 RIBONUCLEASE H2 SUBUNIT B RIBONUCLEASE H2 SUBUNIT B nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031;endoribonuclease#PC00094 DROME|FlyBase=FBgn0052687|UniProtKB=Q9W2U2 Q9W2U2 CT7080 PTHR45752:SF13 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 58 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0261952|UniProtKB=Q9VZE5 Q9VZE5 srw PTHR12312:SF16 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 SCW signaling pathway#P06216>TSG#P06330;DPP-SCW signaling pathway#P06212>TSG#P06258;BMP/activin signaling pathway-drosophila#P06211>TSG#P06242;DPP signaling pathway#P06213>TSG#P06287 DROME|FlyBase=FBgn0024997|UniProtKB=Q9W4W4 Q9W4W4 Dmel\CG2681 PTHR45877:SF3 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 RING-TYPE E3 UBIQUITIN TRANSFERASE aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0035290|UniProtKB=A8JNI3 A8JNI3 dsb PTHR11923:SF88 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 DEBRIS BUSTER, ISOFORM D cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0028991|UniProtKB=A1Z995 A1Z995 seq PTHR24330:SF10 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN B-H1-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0030452|UniProtKB=Q9VYG7 Q9VYG7 MFS10 PTHR11662:SF462 SOLUTE CARRIER FAMILY 17 FI19708P1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0039277|UniProtKB=Q9VBX6 Q9VBX6 Nepl16 PTHR11733:SF209 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI20018P1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0024150|UniProtKB=Q9VP76 Q9VP76 Ac78C PTHR45627:SF1 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 8 phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 DROME|FlyBase=FBgn0041239|UniProtKB=P58962 P58962 Gr58a PTHR21143:SF135 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY RECEPTOR 58A-RELATED cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;cell body#GO:0044297;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038244|UniProtKB=Q29R10 Q29R10 anon-WO0118547.245 PTHR24409:SF433 ZINC FINGER PROTEIN 142 LD24322P transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0039300|UniProtKB=Q9VBU9 Q9VBU9 RpS27 PTHR11594:SF0 40S RIBOSOMAL PROTEIN S27 40S RIBOSOMAL PROTEIN S27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;translation#GO:0006412;nucleic acid biosynthetic process#GO:0141187;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0086348|UniProtKB=Q9VSL3 Q9VSL3 se PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA antioxidant activity#GO:0016209;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0035900|UniProtKB=Q9VSK8 Q9VSK8 ZC3H3 PTHR46156:SF1 CCCH ZINGC FINGER ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3 DROME|FlyBase=FBgn0036107|UniProtKB=Q9VTC4 Q9VTC4 galla-2 PTHR12377:SF0 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0039936|UniProtKB=Q7KQM6 Q7KQM6 Gyf PTHR14445:SF36 GRB10 INTERACTING GYF PROTEIN FI03272P-RELATED translation regulator activity#GO:0045182 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DROME|FlyBase=FBgn0260442|UniProtKB=Q9VSL8 Q9VSL8 rhea PTHR19981:SF1 TALIN RHEA, ISOFORM B cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 Integrin signalling pathway#P00034>Talin#P00943 DROME|FlyBase=FBgn0041241|UniProtKB=P58961 P58961 Gr47b PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0031148|UniProtKB=Q9VRD9 Q9VRD9 Cbs PTHR10314:SF194 CYSTATHIONINE BETA-SYNTHASE CYSTATHIONINE BETA-SYNTHASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 lyase#PC00144;metabolite interconversion enzyme#PC00262 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 DROME|FlyBase=FBgn0034264|UniProtKB=A1ZAY1 A1ZAY1 Dlish PTHR15176:SF1 NEPHROCYSTIN NEPHROCYSTIN-1 cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;organelle assembly#GO:0070925 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary base#GO:0097546;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869 cell junction protein#PC00070 DROME|FlyBase=FBgn0039183|UniProtKB=Q9VC93 Q9VC93 Dis3 PTHR23355:SF35 RIBONUCLEASE EXOSOME COMPLEX EXONUCLEASE RRP44 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981 exoribonuclease#PC00099 DROME|FlyBase=FBgn0264712|UniProtKB=Q9VNB2 Q9VNB2 Dmel\CG1172 PTHR13609:SF4 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED RE42193P ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0061361|UniProtKB=Q8SYJ9 Q8SYJ9 Tcs1 PTHR17490:SF16 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biological regulation#GO:0065007;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;regulation of biological quality#GO:0065008;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0263602|UniProtKB=Q9VUX9 Q9VUX9 Tasp1 PTHR10188:SF8 L-ASPARAGINASE THREONINE ASPARTASE 1 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protease#PC00190 DROME|FlyBase=FBgn0031770|UniProtKB=Q9VMI4 Q9VMI4 Dmel\CG13995 PTHR24224:SF38 CARDIOACCELERATORY PEPTIDE RECEPTOR-RELATED CARDIOACCELERATORY PEPTIDE RECEPTOR-RELATED G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0051344|UniProtKB=Q95U32 Q95U32 Rpb7 PTHR37159:SF1 GH11867P GH11867P DROME|FlyBase=FBgn0039638|UniProtKB=Q9VAP2 Q9VAP2 dgt6 PTHR16151:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028734|UniProtKB=Q9NFU0 Q9NFU0 Fmr1 PTHR10603:SF7 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN FRAGILE X MESSENGER RIBONUCLEOPROTEIN 1 HOMOLOG mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;animal gross anatomical part developmental process#GO:0160108;regulation of mRNA stability#GO:0043488;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;animal organ development#GO:0048513;regulation of mRNA metabolic process#GO:1903311;positive regulation of cell differentiation#GO:0045597;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;regulation of trans-synaptic signaling#GO:0099177;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of RNA metabolic process#GO:0051252;positive regulation of translation#GO:0045727;regulation of nervous system development#GO:0051960;nucleic acid transport#GO:0050657;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of RNA stability#GO:0043487;positive regulation of neurogenesis#GO:0050769;regulation of cell communication#GO:0010646;mRNA transport#GO:0051028;modulation of chemical synaptic transmission#GO:0050804;establishment of RNA localization#GO:0051236;regulation of developmental process#GO:0050793;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound transport#GO:0015931;regulation of neurogenesis#GO:0050767;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;regulation of neuronal synaptic plasticity#GO:0048168;regulation of cell differentiation#GO:0045595;transport#GO:0006810;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;post-transcriptional regulation of gene expression#GO:0010608;regulation of synaptic plasticity#GO:0048167;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;nucleus#GO:0005634;neuron projection#GO:0043005;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;translation factor#PC00223 DROME|FlyBase=FBgn0035137|UniProtKB=Q9I7U7 Q9I7U7 Dmel\CG1233 PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0000439|UniProtKB=P07548 P07548 Dfd PTHR45771:SF14 HOMEOTIC PROTEIN DEFORMED HOMEOTIC PROTEIN DEFORMED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;anterior/posterior pattern specification#GO:0009952;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0038461|UniProtKB=Q9VEQ2 Q9VEQ2 EMC2B PTHR12760:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 chaperone#PC00072 DROME|FlyBase=FBgn0283500|UniProtKB=Q9W0I6 Q9W0I6 Sac1 PTHR45662:SF2 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 lipid modification#GO:0030258;dephosphorylation#GO:0016311;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0024321|UniProtKB=Q9VFK4 Q9VFK4 NK7.1 PTHR24340:SF70 HOMEOBOX PROTEIN NKX NK7.1, ISOFORM A RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0039702|UniProtKB=Q9VAG4 Q9VAG4 Vps16B PTHR13364:SF6 DEFECTIVE SPERMATOGENESIS PROTEIN 39 SPERMATOGENESIS-DEFECTIVE PROTEIN 39 HOMOLOG macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0051865|UniProtKB=Q8IP99 Q8IP99 Ada1-1 PTHR21277:SF5 TRANSCRIPTIONAL ADAPTER 1 TRANSCRIPTIONAL ADAPTER 1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 DROME|FlyBase=FBgn0038466|UniProtKB=H9ZYQ1 H9ZYQ1 CG8907-RB PTHR12287:SF23 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN AROUSER, ISOFORM A-RELATED protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0027584|UniProtKB=Q9Y141 Q9Y141 GH05741 PTHR11559:SF370 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE-RELATED esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 DROME|FlyBase=FBgn0052442|UniProtKB=Q8SYH1 Q8SYH1 Arv1 PTHR14467:SF0 ARV1 PROTEIN ARV1 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037455|UniProtKB=Q9VI33 Q9VI33 Dmel\CG2336 PTHR21644:SF0 AT02555P-RELATED AT02555P-RELATED DROME|FlyBase=FBgn0041147|UniProtKB=Q9VZL2 Q9VZL2 ida PTHR12830:SF9 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;protein K11-linked ubiquitination#GO:0070979;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;positive regulation of cell cycle process#GO:0090068;protein polyubiquitination#GO:0000209;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of cellular component organization#GO:0051130;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of chromosome separation#GO:1905818;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 DROME|FlyBase=FBgn0028919|UniProtKB=Q9V412 Q9V412 Steep1 PTHR46355:SF1 UPF0428 PROTEIN CXORF56 STING ER EXIT PROTEIN organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;endoplasmic reticulum membrane organization#GO:0090158;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 DROME|FlyBase=FBgn0053558|UniProtKB=A0A0B4JCZ8 A0A0B4JCZ8 mim PTHR15708:SF4 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED FI21477P1-RELATED lipid binding#GO:0008289;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;phospholipid binding#GO:0005543;binding#GO:0005488 membrane organization#GO:0061024;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0261547|UniProtKB=Q9VVC6 Q9VVC6 Exn PTHR12845:SF5 GUANINE NUCLEOTIDE EXCHANGE FACTOR EPHEXIN, ISOFORM D enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of actin filament-based process#GO:0032970;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0263117|UniProtKB=A0A0B4KGJ9 A0A0B4KGJ9 CG13860 PTHR12301:SF8 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 DROME|FlyBase=FBgn0038299|UniProtKB=Q9VFC1 Q9VFC1 Spn88Eb PTHR11461:SF278 SERINE PROTEASE INHIBITOR, SERPIN SERINE PROTEASE INHIBITOR 88EA extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 DROME|FlyBase=FBgn0052152|UniProtKB=X2JB47 X2JB47 Dmel\CG32152 PTHR11006:SF73 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 6 N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0000064|UniProtKB=P07764 P07764 Aldo PTHR11627:SF80 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;fructose-bisphosphate aldolase activity#GO:0004332;aldehyde-lyase activity#GO:0016832 small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 lyase#PC00144;aldolase#PC00044 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 DROME|FlyBase=FBgn0030178|UniProtKB=Q9W2Y3 Q9W2Y3 Naxe PTHR13232:SF10 NAD(P)H-HYDRATE EPIMERASE NAD(P)H-HYDRATE EPIMERASE epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0023180|UniProtKB=Q9Y1B2 Q9Y1B2 Orc6 PTHR13394:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;nuclear origin of replication recognition complex#GO:0005664;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 DROME|FlyBase=FBgn0033362|UniProtKB=A8DY75 A8DY75 Dmel\CG8172 PTHR24253:SF136 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEINASE STUBBLE-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 DROME|Gene_ORFName=Dmel_CG46515|UniProtKB=A0ACD4DBL1 A0ACD4DBL1 CG46515 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DROME|FlyBase=FBgn0261553|UniProtKB=X2JGK1 X2JGK1 CG18490 PTHR22934:SF23 PROTEIN ESC1/WETA-RELATED ZF-C3H1 DOMAIN-CONTAINING PROTEIN regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0037554|UniProtKB=Q9VHV1 Q9VHV1 PolI PTHR46404:SF1 DNA POLYMERASE IOTA DNA POLYMERASE IOTA catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887 DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0028474|UniProtKB=Q9V3Y5 Q9V3Y5 BcDNA.LD23634 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 DROME|FlyBase=FBgn0033913|UniProtKB=Q7K1L4 Q7K1L4 Dmel\CG8468 PTHR11360:SF320 MONOCARBOXYLATE TRANSPORTER SD10469P monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0029833|UniProtKB=Q9W445 Q9W445 MCTS1 PTHR22798:SF0 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translation initiation factor#PC00224 DROME|FlyBase=FBgn0037761|UniProtKB=Q9VH59 Q9VH59 Dmel\CG8534 PTHR11157:SF116 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0053137|UniProtKB=A1Z993 A1Z993 CG4023 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0031444|UniProtKB=Q9VQE6 Q9VQE6 Trf4 PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;Huntington disease#P00029>TBP#P00779 DROME|FlyBase=FBgn0261285|UniProtKB=E2QD26 E2QD26 Ppcs PTHR12290:SF2 CORNICHON-RELATED PHOSPHOPANTOTHENATE--CYSTEINE LIGASE membrane traffic protein#PC00150 Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 DROME|FlyBase=FBgn0024184|UniProtKB=O77215 O77215 unc-4 PTHR46799:SF3 HOMEOBOX PROTEIN UNC-4 HOMOLOG HOMEOBOX PROTEIN UNC-4 double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0029737|UniProtKB=Q9W4F7 Q9W4F7 Hgsnat PTHR31061:SF38 LD22376P HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE, ISOFORM A acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 protein catabolic process#GO:0030163;glycoprotein metabolic process#GO:0009100;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 DROME|FlyBase=FBgn0053158|UniProtKB=Q9VV61 Q9VV61 CG10162 PTHR42908:SF3 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR-LIKE GTPASE 1 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;translation#GO:0006412;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829 translation elongation factor#PC00222 DROME|FlyBase=FBgn0039329|UniProtKB=Q9VBR9 Q9VBR9 Dmel\CG10669 PTHR24376:SF216 ZINC FINGER PROTEIN DRACULIN-LIKE 3 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0004101|UniProtKB=Q24535 Q24535 bs PTHR48019:SF248 SERUM RESPONSE FACTOR HOMOLOG SERUM RESPONSE FACTOR HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;MADS box transcription factor#PC00250 PDGF signaling pathway#P00047>SRF#P01165 DROME|FlyBase=FBgn0062440|UniProtKB=Q7JX57 Q7JX57 EMRE PTHR33904:SF1 ESSENTIAL MCU REGULATOR, MITOCHONDRIAL ESSENTIAL MCU REGULATOR, MITOCHONDRIAL monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801 transporter complex#GO:1990351;organelle membrane#GO:0031090;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;monoatomic ion channel complex#GO:0034702;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;calcium channel complex#GO:0034704;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0035298|UniProtKB=Q9W058 Q9W058 Scot PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0000416|UniProtKB=Q9Y125 Q9Y125 Sap-r PTHR11480:SF102 SAPOSIN-RELATED BCDNA.GH08312 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;cellular process#GO:0009987;homeostatic process#GO:0042592 lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;late endosome#GO:0005770;endomembrane system#GO:0012505;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0266572|UniProtKB=X2J9Y4 X2J9Y4 ebo PTHR21452:SF4 EXPORTIN-6 EXPORTIN-6 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031 DROME|FlyBase=FBgn0030803|UniProtKB=Q9VX97 Q9VX97 Dmel\CG4880 PTHR10760:SF18 TORSIN LD13476P-RELATED response to misfolded protein#GO:0051788;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;cellular response to stress#GO:0033554;cellular response to misfolded protein#GO:0071218;cellular response to topologically incorrect protein#GO:0035967 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 DROME|FlyBase=FBgn0003499|UniProtKB=A0A0B4KGW2 A0A0B4KGW2 sr PTHR23235:SF60 KRUEPPEL-LIKE TRANSCRIPTION FACTOR STRIPE, ISOFORM D double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0000575|UniProtKB=P18491 P18491 emc PTHR11723:SF17 DNA-BINDING PROTEIN INHIBITOR PROTEIN EXTRA-MACROCHAETAE transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0038330|UniProtKB=Q9VF72 Q9VF72 Dmel\CG14868 PTHR21682:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 DROME|FlyBase=FBgn0264491|UniProtKB=O01367 O01367 how PTHR11208:SF42 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING RNA-BINDING PROTEIN QKI RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0039854|UniProtKB=Q95TK5 Q95TK5 Dmel\CG1635 PTHR12655:SF10 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL hydrolase activity#GO:0016787;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 DROME|FlyBase=FBgn0263911|UniProtKB=Q9VP19 Q9VP19 COX8 PTHR16717:SF5 CYTOCHROME C OXIDASE POLYPEPTIDE VIII CYTOCHROME C OXIDASE SUBUNIT 8, ISOFORM A intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;transporter complex#GO:1990351 oxidase#PC00175;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0041712|UniProtKB=Q9W1R1 Q9W1R1 yellow-d PTHR10009:SF7 PROTEIN YELLOW-RELATED GH10609P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0002622|UniProtKB=Q06559 Q06559 RpS3 PTHR11760:SF76 30S/40S RIBOSOMAL PROTEIN S3 SMALL RIBOSOMAL SUBUNIT PROTEIN US3 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;positive regulation of cell communication#GO:0010647;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of apoptotic process#GO:0043065;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 ribosomal protein#PC00202 DROME|FlyBase=FBgn0010223|UniProtKB=Q05337 Q05337 Galphaf PTHR10218:SF367 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(F) SUBUNIT ALPHA hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;sensory perception of chemical stimulus#GO:0007606;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 G-protein#PC00020;heterotrimeric G-protein#PC00117 Enkephalin release#P05913>G-Protein (s)#P05977;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430 DROME|FlyBase=FBgn0037884|UniProtKB=Q9VGQ8 Q9VGQ8 Arfip PTHR12141:SF5 ARFAPTIN-RELATED ARFAPTIN molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0027611|UniProtKB=Q8IPB7 Q8IPB7 LManII PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 glycosidase#PC00110;hydrolase#PC00121 DROME|FlyBase=FBgn0003308|UniProtKB=P10351 P10351 ry PTHR11908:SF168 XANTHINE DEHYDROGENASE XANTHINE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Purine metabolism#P02769>Xanthine Oxidase#P03116;Adenine and hypoxanthine salvage pathway#P02723>Xanthine dehydrogenase#P02809 DROME|FlyBase=FBgn0037185|UniProtKB=Q9VNR8 Q9VNR8 Dmel\CG11367 PTHR46593:SF2 TRANSMEMBRANE PROTEIN 64 LD47277P calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0010808|UniProtKB=Q9VA18 Q9VA18 Chchd3 PTHR21588:SF18 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 MICOS COMPLEX SUBUNIT MIC19 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0039622|UniProtKB=Q9VAR1 Q9VAR1 eIF4E6 PTHR11960:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 DROME|FlyBase=FBgn0030208|UniProtKB=Q9W2U4 Q9W2U4 PPP4R2r PTHR16487:SF0 PPP4R2-RELATED PROTEIN SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 phosphatase modulator#PC00184 DROME|FlyBase=FBgn0011586|UniProtKB=Q24337 Q24337 e(r) PTHR12373:SF0 ENHANCER OF RUDIMENTARY ERH ENHANCER OF RUDIMENTARY HOMOLOG molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 regulation of chromatin organization#GO:1902275;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0033885|UniProtKB=A1Z9J4 A1Z9J4 DJ-1alpha PTHR48094:SF28 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PROTEIN DJ-1ALPHA-RELATED lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;ketone metabolic process#GO:0042180;cellular detoxification of aldehyde#GO:0110095;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;response to stress#GO:0006950;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;alcohol biosynthetic process#GO:0046165;response to chemical#GO:0042221;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;response to oxidative stress#GO:0006979 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0039890|UniProtKB=Q7JUN3 Q7JUN3 Abcd1 PTHR11384:SF67 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carboxylic acid transmembrane transporter activity#GO:0046943;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;nucleotide binding#GO:0000166;monocarboxylic acid transmembrane transporter activity#GO:0008028 peroxisomal transport#GO:0043574;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;lipid oxidation#GO:0034440;carboxylic acid transmembrane transport#GO:1905039;catabolic process#GO:0009056;primary metabolic process#GO:0044238;lipid modification#GO:0030258;establishment of localization#GO:0051234;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;transport#GO:0006810;fatty acid metabolic process#GO:0006631;intracellular transport#GO:0046907;lipid transport#GO:0006869;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;macromolecule localization#GO:0033036;fatty acid catabolic process#GO:0009062;transmembrane transport#GO:0055085;cellular localization#GO:0051641;peroxisome organization#GO:0007031;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;cellular component organization or biogenesis#GO:0071840;fatty acid oxidation#GO:0019395;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;metabolic process#GO:0008152;lipid catabolic process#GO:0016042;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0002543|UniProtKB=M9PC46 M9PC46 robo2 PTHR12231:SF279 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN ROUNDABOUT 1, ISOFORM A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;cell recognition#GO:0008037;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039 cell periphery#GO:0071944;main axon#GO:0044304;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;neuron projection membrane#GO:0032589;axon#GO:0030424;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0038592|UniProtKB=Q9VEA3 Q9VEA3 Dmel\CG18599 PTHR24339:SF67 HOMEOBOX PROTEIN EMX-RELATED GNOT2 HOMEODOMAIN PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0038571|UniProtKB=Q9VEC8 Q9VEC8 CG32920 PTHR46555:SF1 UBIQUITIN-LIKE PROTEIN 4A UBIQUITIN-LIKE PROTEIN 4A DROME|FlyBase=FBgn0011244|UniProtKB=Q9VPS5 Q9VPS5 Hsp60B PTHR45633:SF53 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN HOMOLOG 1, MITOCHONDRIAL-RELATED protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;localization#GO:0051179;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;cellular component organization#GO:0016043;apoptotic process#GO:0006915;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;cellular localization#GO:0051641;organelle organization#GO:0006996;response to stress#GO:0006950;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840 organelle membrane#GO:0031090;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0283649|UniProtKB=Q9VUV7 Q9VUV7 elgi PTHR15315:SF26 RING FINGER PROTEIN 41, 151 E3 UBIQUITIN-PROTEIN LIGASE NRDP1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 DROME|FlyBase=FBgn0033845|UniProtKB=Q7K3L1 Q7K3L1 mars PTHR12353:SF1 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 5 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;centrosome localization#GO:0051642;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;kinetochore organization#GO:0051383;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0039269|UniProtKB=Q8IMT8 Q8IMT8 veli PTHR14063:SF10 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;vesicle localization#GO:0051648;establishment of localization#GO:0051234;transport#GO:0006810;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of growth#GO:0040008;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;secretion#GO:0046903;regulation of synapse structure or activity#GO:0050803;localization#GO:0051179;cell communication#GO:0007154;regulation of cell junction assembly#GO:1901888;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;signal release#GO:0023061;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;regulation of cellular component biogenesis#GO:0044087;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of synapse organization#GO:0050807 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070 DROME|FlyBase=FBgn0014417|UniProtKB=Q9VLL5 Q9VLL5 Naglu PTHR12872:SF5 ALPHA-N-ACETYLGLUCOSAMINIDASE ALPHA-N-ACETYLGLUCOSAMINIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035865|UniProtKB=Q9VSG7 Q9VSG7 Dmel\CG7201 PTHR21398:SF24 AGAP007094-PA PROTEASOME ASSEMBLY CHAPERONE 2-RELATED DROME|FlyBase=FBgn0052000|UniProtKB=A8DZ26 A8DZ26 anne PTHR45630:SF23 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;polyamine transmembrane transporter activity#GO:0015203 transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;nitrogen compound transport#GO:0071705;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;localization#GO:0051179;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068 DROME|FlyBase=FBgn0029929|UniProtKB=Q9W3T2 Q9W3T2 Dmel\CG4593 PTHR13049:SF2 DUF814-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 25 DROME|FlyBase=FBgn0035421|UniProtKB=Q9VZS6 Q9VZS6 nSMase PTHR12393:SF8 SPHINGOMYELIN PHOSPHODIESTERASE RELATED SPHINGOMYELIN PHOSPHODIESTERASE 2 lipase activity#GO:0016298;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 ceramide metabolic process#GO:0006672;phosphorus metabolic process#GO:0006793;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;lipid biosynthetic process#GO:0008610;sphingomyelin metabolic process#GO:0006684;biosynthetic process#GO:0009058 caveola#GO:0005901;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane microdomain#GO:0098857;endoplasmic reticulum#GO:0005783;membrane raft#GO:0045121;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;plasma membrane raft#GO:0044853;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185 DROME|FlyBase=FBgn0036640|UniProtKB=Q9VV73 Q9VV73 nxf2 PTHR10662:SF22 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0029660|UniProtKB=Q9W4S3 Q9W4S3 Dmel\CG10801 PTHR22667:SF0 AT01380P-RELATED AT01380P-RELATED DROME|FlyBase=FBgn0011726|UniProtKB=P45594 P45594 tsr PTHR11913:SF122 COFILIN-RELATED COFILIN_ACTIN-DEPOLYMERIZING FACTOR HOMOLOG-RELATED protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;protein depolymerization#GO:0051261;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament depolymerization#GO:0030042;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;actin filament-based process#GO:0030029 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0039846|UniProtKB=Q9V9X7 Q9V9X7 PNPase PTHR11252:SF0 POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;mitochondrial RNA 3'-end processing#GO:0000965;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 nucleotidyltransferase#PC00174 DROME|FlyBase=FBgn0031902|UniProtKB=Q9VM26 Q9VM26 Wnt6 PTHR12027:SF72 WNT RELATED PROTEIN WNT-6 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;system development#GO:0048731;cell fate commitment#GO:0045165;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 DROME|FlyBase=FBgn0038142|UniProtKB=Q9VFW3 Q9VFW3 CheA87a PTHR21112:SF10 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 87A DROME|FlyBase=FBgn0039509|UniProtKB=Q9VB47 Q9VB47 bigmax PTHR15741:SF25 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MAX-LIKE PROTEIN X sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0026718|UniProtKB=Q7KTI0 Q7KTI0 Agpat2 PTHR10434:SF53 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0035521|UniProtKB=Q9VZE9 Q9VZE9 VhaM9.7-a PTHR12263:SF0 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic ion transport#GO:0006811 membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0027086|UniProtKB=Q8MSW0 Q8MSW0 IleRS PTHR42780:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cytosol#GO:0005829;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0030230|UniProtKB=Q9W2R9 Q9W2R9 Rph PTHR45729:SF6 RABPHILIN, ISOFORM A RABPHILIN, ISOFORM A regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;synaptic signaling#GO:0099536;positive regulation of secretion by cell#GO:1903532;synaptic vesicle exocytosis#GO:0016079;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;positive regulation of secretion#GO:0051047;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;export from cell#GO:0140352;signaling#GO:0023052;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;localization#GO:0051179;regulation of secretion#GO:0051046;cell communication#GO:0007154;secretion#GO:0046903;regulation of exocytosis#GO:0017157;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 DROME|FlyBase=FBgn0031289|UniProtKB=Q9VPU6 Q9VPU6 Dmel\CG13950 PTHR11346:SF147 GALECTIN GALECTIN binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0023525|UniProtKB=Q95R34 Q95R34 62D9.a PTHR10174:SF222 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED GH10083P-RELATED ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0000039|UniProtKB=P17644 P17644 nAChRalpha2 PTHR18945:SF430 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-LIKE 2-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220 signaling receptor complex#GO:0043235;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 DROME|FlyBase=FBgn0085483|UniProtKB=A8JNG6 A8JNG6 Dmel\CG34454 PTHR21179:SF1 SERINE-TYPE ENDOPEPTIDASE INHIBITOR KAZ1-TYPE SERINE PROTEASE INHIBITOR-LIKE PROTEIN TYPE EPSILON-RELATED protease inhibitor#PC00191 DROME|FlyBase=FBgn0040534|UniProtKB=Q9VHI4 Q9VHI4 Sf3b5 PTHR20978:SF0 SPLICING FACTOR 3B SUBUNIT 5 SPLICING FACTOR 3B SUBUNIT 5 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 DROME|FlyBase=FBgn0029831|UniProtKB=Q9W448 Q9W448 141233_at PTHR11610:SF198 LIPASE LD47264P lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0027291|UniProtKB=Q9VWH4 Q9VWH4 Idh3a PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;alcohol metabolic process#GO:0006066;cellular process#GO:0009987 oxidoreductase#PC00176;dehydrogenase#PC00092 Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001 DROME|FlyBase=FBgn0037964|UniProtKB=Q9VGG4 Q9VGG4 gi7299531 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED DROME|FlyBase=FBgn0039120|UniProtKB=Q9VCH5 Q9VCH5 Nup98-96 PTHR23198:SF6 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96 binding#GO:0005488;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of nuclear pore#GO:0017056 macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of RNA localization#GO:0051236;telomere localization#GO:0034397;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;chromosome localization#GO:0050000;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;cellular component organization#GO:0016043;cellular localization#GO:0051641;protein transport#GO:0015031;protein import into nucleus#GO:0006606;telomere tethering at nuclear periphery#GO:0034398 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227 transporter#PC00227 DROME|FlyBase=FBgn0035632|UniProtKB=Q9VRP4 Q9VRP4 Ppat-Dpck PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED DEPHOSPHO-COA KINASE DOMAIN-CONTAINING PROTEIN phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 kinase#PC00137;metabolite interconversion enzyme#PC00262 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 DROME|FlyBase=FBgn0034793|UniProtKB=Q9W1X9 Q9W1X9 asrij PTHR13336:SF3 OVARIAN CARCINOMA IMMUNOREACTIVE ANTIGEN OCIA DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0039621|UniProtKB=Q9VAR2 Q9VAR2 Dmel\CG14518 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0260860|UniProtKB=Q9VA95 Q9VA95 Bet5 PTHR23249:SF16 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 TRAPP complex#GO:0030008;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0004053|UniProtKB=P09089 P09089 zen PTHR45664:SF22 PROTEIN ZERKNUELLT 1-RELATED HOMEOTIC PROTEIN BICOID-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0037364|UniProtKB=Q9VNG6 Q9VNG6 Rab23 PTHR24073:SF209 DRAB5-RELATED RAS-RELATED PROTEIN RAB-23 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular transport#GO:0046907;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;autophagosome organization#GO:1905037;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;autophagy#GO:0006914;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;organelle assembly#GO:0070925;cellular localization#GO:0051641;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;vacuole organization#GO:0007033;cellular component organization#GO:0016043;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;autophagosome#GO:0005776;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0031332|UniProtKB=Q9VQ01 Q9VQ01 Dmel\CG5556 PTHR18901:SF48 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 DROME|FlyBase=FBgn0023508|UniProtKB=O46094 O46094 Ocrl PTHR11200:SF303 INOSITOL 5-PHOSPHATASE EG:86E4.5 PROTEIN phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0032119|UniProtKB=Q9VLB9 Q9VLB9 Dmel\CG3769 PTHR13236:SF0 DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2 CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;intraciliary transport involved in cilium assembly#GO:0035735;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dynein complex#GO:0030286;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0036872|UniProtKB=Q9VVZ6 Q9VVZ6 Dmel\CG12519 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0262103|UniProtKB=A1ZBC4 A1ZBC4 Sik3 PTHR24343:SF299 SERINE/THREONINE KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0038447|UniProtKB=Q9VET2 Q9VET2 Dmel\CG14892 PTHR24256:SF470 TRYPTASE-RELATED SERINE PROTEASE 33 serine protease#PC00203 DROME|FlyBase=FBgn0032618|UniProtKB=Q9VJG5 Q9VJG5 C4st PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 DROME|FlyBase=FBgn0051122|UniProtKB=Q9VE69 Q9VE69 CG14308 PTHR31296:SF1 UPF0565 PROTEIN C2ORF69 MITOCHONDRIAL PROTEIN C2ORF69 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0045866|UniProtKB=Q8SXY6 Q8SXY6 bai PTHR22811:SF184 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TMED10 PROTEIN membrane traffic protein#PC00150;vesicle coat protein#PC00235 DROME|FlyBase=FBgn0037199|UniProtKB=Q9VNQ3 Q9VNQ3 EMC4 PTHR19315:SF9 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 DROME|FlyBase=FBgn0040973|UniProtKB=Q6IHK7 Q6IHK7 Dmel\CG16824 PTHR28632:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 DROME|FlyBase=FBgn0030670|UniProtKB=Q8SX37 Q8SX37 Pis PTHR15362:SF4 PHOSPHATIDYLINOSITOL SYNTHASE CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220 DROME|FlyBase=FBgn0000635|UniProtKB=P34082 P34082 Fas2 PTHR10075:SF119 BASIGIN RELATED FASCICLIN-2 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0267326|UniProtKB=Q9VLY6 Q9VLY6 Ntl PTHR11616:SF328 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;import into cell#GO:0098657;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;monoatomic cation transport#GO:0006812;localization#GO:0051179;glycine transport#GO:0015816 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 DROME|FlyBase=FBgn0264006|UniProtKB=M9PF56 M9PF56 dysc PTHR23116:SF39 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED DYSCHRONIC, ISOFORM G membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0031688|UniProtKB=Q9VMT6 Q9VMT6 Cyp28d2 PTHR24292:SF84 CYTOCHROME P450 CYTOCHROME P450 28A5-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0038065|UniProtKB=Q9VG51 Q9VG51 Snx3 PTHR45963:SF2 RE52028P SORTING NEXIN-3 DROME|FlyBase=FBgn0005775|UniProtKB=Q01819 Q01819 Con PTHR45617:SF170 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 32 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0027090|UniProtKB=Q9Y105 Q9Y105 GlnRS PTHR43097:SF16 GLUTAMINE-TRNA LIGASE GLUTAMINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 DROME|FlyBase=FBgn0004244|UniProtKB=P25123 P25123 Rdl PTHR18945:SF856 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0260985|UniProtKB=P53034 P53034 RfC4 PTHR11669:SF5 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 2 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity#GO:0140657 cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;replication fork#GO:0005657;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 DROME|FlyBase=FBgn0029856|UniProtKB=R9PY16 R9PY16 Ubi-p5E5 PTHR10666:SF438 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN ES31 FUSION PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 DROME|FlyBase=FBgn0262801|UniProtKB=O97066 O97066 twr PTHR10806:SF6 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 peptidase complex#GO:1905368;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 serine protease#PC00203 Vasopressin synthesis#P04395>Signal Peptidase#P04589;Endothelin signaling pathway#P00019>signal peptidase#P00573 DROME|FlyBase=FBgn0039154|UniProtKB=Q9VCC8 Q9VCC8 Npc2f PTHR11306:SF0 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED LP08842P-RELATED lipid binding#GO:0008289;steroid binding#GO:0005496;sterol binding#GO:0032934;binding#GO:0005488 organic hydroxy compound transport#GO:0015850;localization#GO:0051179;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 DROME|FlyBase=FBgn0050382|UniProtKB=E1JGZ9 E1JGZ9 Prosalpha1R PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0038391|UniProtKB=Q9VF00 Q9VF00 GATAe PTHR10071:SF337 TRANSCRIPTION FACTOR GATA FAMILY MEMBER BOX A-BINDING FACTOR-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell fate commitment#GO:0045165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036603|UniProtKB=Q9VV27 Q9VV27 Dmel\CG13062 PTHR34931:SF4 FI02976P-RELATED GEO13385P1-RELATED DROME|FlyBase=FBgn0035059|UniProtKB=Q9W112 Q9W112 Dmel\CG3894 PTHR12429:SF8 NEURALIZED NEURALIZED-LIKE PROTEIN 2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 DROME|FlyBase=FBgn0053080|UniProtKB=Q9W490 Q9W490 CG15774 PTHR43053:SF6 GLYCOSIDASE FAMILY 31 GLYCOSYL HYDROLASE FAMILY 31 C-TERMINAL DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;glucosidase#PC00108;hydrolase#PC00121 DROME|FlyBase=FBgn0029745|UniProtKB=Q9W4E6 Q9W4E6 Rpn13R PTHR12225:SF0 ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541 DROME|FlyBase=FBgn0053203|UniProtKB=B7Z0R3 B7Z0R3 CG14525 PTHR20855:SF138 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0036155|UniProtKB=Q9VTH8 Q9VTH8 Dmel\CG6163 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0033450|UniProtKB=A1Z802 A1Z802 Lsm11 PTHR21415:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0028560|UniProtKB=Q7K2U8 Q7K2U8 sut4 PTHR48021:SF102 FAMILY NOT NAMED GH07001P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0045470|UniProtKB=Q8IN23 Q8IN23 Gr93b PTHR21143:SF134 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 32A-RELATED dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0034439|UniProtKB=A0A0B4KEU8 A0A0B4KEU8 Dmel\CG10062 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0037241|UniProtKB=Q9VN16 Q9VN16 Dmel\CG14646 PTHR31322:SF2 E3 UBIQUITIN-PROTEIN LIGASE TM129 E3 UBIQUITIN-PROTEIN LIGASE TM129 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0032341|UniProtKB=Q8MQS4 Q8MQS4 Reps PTHR11216:SF174 EH DOMAIN GH06923P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0015808|UniProtKB=Q9VJ43 Q9VJ43 ScpX PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED STEROL CARRIER PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0026479|UniProtKB=Q9VQE0 Q9VQE0 Drp1 PTHR11566:SF237 DYNAMIN DYNAMIN GTPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;protein binding#GO:0005515;GTPase activity#GO:0003924;microtubule binding#GO:0008017;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 peroxisome organization#GO:0007031;organelle localization#GO:0051640;mitochondrion localization#GO:0051646;organelle fission#GO:0048285;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0026379|UniProtKB=Q7KMQ6 Q7KMQ6 Pten PTHR12305:SF100 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>PTEN#P00824;p53 pathway#P00059>PTEN#G01579;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480;PI3 kinase pathway#P00048>PTEN#P01189;p53 pathway feedback loops 2#P04398>PTEN#G04714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;p53 pathway feedback loops 2#P04398>PTEN#P04658 DROME|FlyBase=FBgn0285971|UniProtKB=Q9VLK8 Q9VLK8 prg PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0287187|UniProtKB=Q8SYP9 Q8SYP9 mRpS5 PTHR13718:SF61 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 DROME|FlyBase=FBgn0028992|UniProtKB=Q9VEK8 Q9VEK8 sds22 PTHR45973:SF23 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7 molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 chromosome segregation#GO:0007059;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0038032|UniProtKB=Q9VG87 Q9VG87 CG32919 PTHR11011:SF60 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521 peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0024293|UniProtKB=A1Z6V5 A1Z6V5 Spn43Ab PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 DROME|FlyBase=FBgn0036492|UniProtKB=Q9VUM7 Q9VUM7 Best3 PTHR10736:SF65 BESTROPHIN BESTROPHIN 1, ISOFORM C-RELATED channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0031520|UniProtKB=Q9VQN9 Q9VQN9 Dmel\CG8837 PTHR23500:SF453 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER IP12678P secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0028379|UniProtKB=Q9VSD3 Q9VSD3 fan PTHR10809:SF6 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN AT11025P-RELATED protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043 organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0023536|UniProtKB=Q8SWW9 Q8SWW9 EG:171D11.2 PTHR24221:SF650 ATP-BINDING CASSETTE SUB-FAMILY B LD18126P active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0017581|UniProtKB=Q9VGI4 Q9VGI4 Lk6 PTHR24349:SF527 SERINE/THREONINE-PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683;catalytic activity, acting on a protein#GO:0140096;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0036440|UniProtKB=Q9VUG6 Q9VUG6 Dmel\CG17177 PTHR42995:SF5 ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA, CHLOROPLASTIC ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA, CHLOROPLASTIC monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 DROME|FlyBase=FBgn0034540|UniProtKB=D0IQL1 D0IQL1 Lrt PTHR24366:SF165 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH TENDON-SPECIFIC PROTEIN, ISOFORM C immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|Gene_ORFName=Dmel_CG4396|UniProtKB=A0ACD4DAU9 A0ACD4DAU9 fne PTHR10352:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G FOUND IN NEURONS, ISOFORM K-RELATED nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 DROME|FlyBase=FBgn0036447|UniProtKB=Q9VUH5 Q9VUH5 Mgat4b PTHR12062:SF9 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A, ISOFORM A-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi stack#GO:0005795;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;Golgi apparatus subcompartment#GO:0098791 transferase#PC00220 DROME|FlyBase=FBgn0015477|UniProtKB=A1Z7S0 A1Z7S0 Rme-8 PTHR36983:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 chaperone#PC00072 DROME|FlyBase=FBgn0051974|UniProtKB=M9PDQ9 M9PDQ9 Dmel\CG31974 PTHR11012:SF55 PROTEIN KINASE-LIKE DOMAIN-CONTAINING T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0261993|UniProtKB=A0A0B4JD04 A0A0B4JD04 Dmel\CG42811 PTHR21398:SF6 AGAP007094-PA SUBFAMILY NOT NAMED DROME|FlyBase=FBgn0035146|UniProtKB=Q8SYC4 Q8SYC4 Dmel\CG13893 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0027590|UniProtKB=Q9XYZ9 Q9XYZ9 GstE12 PTHR43969:SF3 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE E11, ISOFORM A-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0031514|UniProtKB=Q9VQN3 Q9VQN3 OtopLb PTHR21522:SF30 PROTON CHANNEL OTOP GH01206P channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078 transport#GO:0006810;monoatomic ion transport#GO:0006811;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0003865|UniProtKB=P54356 P54356 tsg PTHR12312:SF16 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 SCW signaling pathway#P06216>TSG#P06330;DPP-SCW signaling pathway#P06212>TSG#P06258;BMP/activin signaling pathway-drosophila#P06211>TSG#P06242;DPP signaling pathway#P06213>TSG#P06287 DROME|FlyBase=FBgn0267486|UniProtKB=Q9VJ95 Q9VJ95 Ptp36E PTHR19134:SF567 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE 36E, ISOFORM A phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 protein phosphatase#PC00195;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030733|UniProtKB=Q9VXI6 Q9VXI6 UQCR-14 PTHR12022:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0083986|UniProtKB=Q0KI15 Q0KI15 Dmel\CG34150 PTHR46749:SF1 COMPLEX III ASSEMBLY FACTOR LYRM7 COMPLEX III ASSEMBLY FACTOR LYRM7 cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 chaperone#PC00072 DROME|FlyBase=FBgn0264272|UniProtKB=M9PE53 M9PE53 mwh PTHR45857:SF4 FORMIN-LIKE PROTEIN MULTIPLE WING HAIRS, ISOFORM C DROME|FlyBase=FBgn0030320|UniProtKB=Q9VYW5 Q9VYW5 Dmel\CG2247 PTHR15739:SF5 ZINC FINGER PROTEIN LD23158P DROME|FlyBase=FBgn0051373|UniProtKB=Q8INL3 Q8INL3 Dmel\CG31373 PTHR10458:SF2 PEPTIDE DEFORMYLASE PEPTIDE DEFORMYLASE, MITOCHONDRIAL intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121 DROME|FlyBase=FBgn0040104|UniProtKB=Q9VQU4 Q9VQU4 lectin-24A PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0029158|UniProtKB=Q7JQW6 Q7JQW6 Las PTHR10949:SF0 LIPOYL SYNTHASE LIPOYL SYNTHASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 Lipoate_biosynthesis#P02750>Lipoate synthase#P03004 DROME|FlyBase=FBgn0039770|UniProtKB=Q9VA76 Q9VA76 crhbp PTHR10278:SF0 CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN CORTICOTROPIN-RELEASING HORMONE-BINDING PROTEIN peptide hormone binding#GO:0017046;hormone binding#GO:0042562;binding#GO:0005488 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;regulation of transport#GO:0051049;regulation of localization#GO:0032879;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of hormone secretion#GO:0046883;hormone-mediated signaling pathway#GO:0009755;regulation of secretion by cell#GO:1903530;negative regulation of cell communication#GO:0010648;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;negative regulation of multicellular organismal process#GO:0051241;cellular response to stimulus#GO:0051716;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of secretion#GO:0051046;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0037933|UniProtKB=Q9VGJ9 Q9VGJ9 Ho PTHR10720:SF0 HEME OXYGENASE HEME OXYGENASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;binding#GO:0005488;tetrapyrrole binding#GO:0046906 response to stimulus#GO:0050896;catabolic process#GO:0009056;heme metabolic process#GO:0042168;response to stress#GO:0006950;pigment metabolic process#GO:0042440;cellular process#GO:0009987;response to oxidative stress#GO:0006979;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0010258|UniProtKB=Q9VFT3 Q9VFT3 Rbp4 PTHR48031:SF2 SRA STEM-LOOP-INTERACTING RNA-BINDING PROTEIN, MITOCHONDRIAL RNA-BINDING PROTEIN 4 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0261723|UniProtKB=Q9W064 Q9W064 Dbx PTHR24331:SF0 DBX DBX regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 DROME|FlyBase=FBgn0263079|UniProtKB=M9NDT0 M9NDT0 CG15165 PTHR18863:SF6 TSEC-2-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 170 DROME|FlyBase=FBgn0038964|UniProtKB=Q95WY3 Q95WY3 Nop56 PTHR10894:SF0 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 56 binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;RNA binding#GO:0003723 protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035167|UniProtKB=Q9W0M2 Q9W0M2 Gr61a PTHR21421:SF34 GUSTATORY RECEPTOR GUSTATORY RECEPTOR FOR SUGAR TASTE 61A-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;sensory perception#GO:0007600 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0040650|UniProtKB=Q9VRA0 Q9VRA0 Dmel\CG15456 PTHR15124:SF27 SELENOPROTEIN W MIGRATION AND INVASION ENHANCER 1 positive regulation of cellular component biogenesis#GO:0044089;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DROME|FlyBase=FBgn0032685|UniProtKB=Q9VJ80 Q9VJ80 Dmel\CG10211 PTHR11475:SF150 OXIDASE/PEROXIDASE LD42267P oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 DROME|FlyBase=FBgn0050288|UniProtKB=Q8IRK6 Q8IRK6 Dmel\CG30288 PTHR24256:SF546 TRYPTASE-RELATED MIP11562P-RELATED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0037712|UniProtKB=Q9VHB4 Q9VHB4 Dmel\CG16789 PTHR14690:SF0 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 DROME|Gene_ORFName=Dmel_CG46505|UniProtKB=A0ACD4DAW2 A0ACD4DAW2 CG46505 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;RNA metabolic process#GO:0016070;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0029663|UniProtKB=B7Z122 B7Z122 Dmel\CG10804 PTHR11616:SF182 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 DROME|FlyBase=FBgn0033312|UniProtKB=A1Z7G6 A1Z7G6 AAF59068 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0032814|UniProtKB=Q9VIS9 Q9VIS9 Dmel\CG10366 PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0032457|UniProtKB=Q9VK55 Q9VK55 Dmel\CG15483 PTHR47412:SF1 FI01434P-RELATED FI01434P-RELATED DROME|FlyBase=FBgn0283442|UniProtKB=P09052 P09052 vas PTHR47958:SF11 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 developmental process involved in reproduction#GO:0003006;cellular process#GO:0009987;germ cell development#GO:0007281;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;sexual reproduction#GO:0019953;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organismal reproductive process#GO:0048609 nucleus#GO:0005634;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032 DROME|FlyBase=FBgn0034494|UniProtKB=Q8SWV5 Q8SWV5 dSLC5A3 PTHR42985:SF51 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER LD47995P-RELATED secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0020503|UniProtKB=Q9VJE5 Q9VJE5 CLIP-190 PTHR18916:SF93 DYNACTIN 1-RELATED MICROTUBULE-BINDING RESTIN HOMOLOG chaperone#PC00072 DROME|FlyBase=FBgn0029131|UniProtKB=Q9V9C8 Q9V9C8 Debcl PTHR11256:SF63 BCL-2 RELATED BG1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 DROME|FlyBase=FBgn0053643|UniProtKB=Q4ABF8 Q4ABF8 Dmel\CG33643 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0053533|UniProtKB=Q59DY5 Q59DY5 lectin-37Db PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN binding#GO:0005488;signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0040233|UniProtKB=Q9VKH9 Q9VKH9 cana PTHR47968:SF80 CENTROMERE PROTEIN E CENP-ANA, ISOFORM A-RELATED protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cell cycle#GO:0007049;cellular process#GO:0009987;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 DROME|FlyBase=FBgn0031164|UniProtKB=Q9VRF6 Q9VRF6 Dmel\CG1724 PTHR10485:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 AT05822P-RELATED transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 transporter#PC00227 DROME|FlyBase=FBgn0036847|UniProtKB=Q9VVW7 Q9VVW7 CNPYb PTHR15382:SF8 CTG4A-RELATED CANOPY B DROME|FlyBase=FBgn0051119|UniProtKB=Q9VC26 Q9VC26 HDAC11 PTHR10625:SF23 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 11 histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824 epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0032699|UniProtKB=Q9VJ64 Q9VJ64 Dmel\CG10383 PTHR48187:SF2 LD21810P LD21810P DROME|FlyBase=FBgn0005586|UniProtKB=P25228 P25228 Rab3 PTHR47980:SF19 LD44762P RAS-RELATED PROTEIN RAB-3 myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;secretion by cell#GO:0032940;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;cell junction#GO:0030054 DROME|FlyBase=FBgn0050046|UniProtKB=A1Z8W6 A1Z8W6 CG17740 PTHR11311:SF16 SPONDIN SPONDIN-1 cellular process#GO:0009987;cell adhesion#GO:0007155 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0044050|UniProtKB=Q9VT52 Q9VT52 Ilp3 PTHR13647:SF4 INSULIN-LIKE PEPTIDE 2-RELATED INSULIN-LIKE PEPTIDE 1-RELATED DROME|FlyBase=FBgn0031463|UniProtKB=Q9VQH1 Q9VQH1 G6p PTHR12591:SF0 GLUCOSE-6-PHOSPHATASE FI19814P1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0031322|UniProtKB=Q9VPY9 Q9VPY9 Dmel\CG5001 PTHR24078:SF582 DNAJ HOMOLOG SUBFAMILY C MEMBER FI02090P binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0036433|UniProtKB=Q9VUF9 Q9VUF9 Dmel\CG9628 PTHR36692:SF1 PROTEIN SNAKESKIN GH08457P plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0033955|UniProtKB=A0A0B4LFF4 A0A0B4LFF4 Targ PTHR11360:SF286 MONOCARBOXYLATE TRANSPORTER GH22266P-RELATED monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 DROME|FlyBase=FBgn0032449|UniProtKB=Q9VK64 Q9VK64 Dmel\CG17036 PTHR10686:SF18 FOLATE TRANSPORTER IP11787P-RELATED cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 DROME|FlyBase=FBgn0015834|UniProtKB=O02195 O02195 eIF3i PTHR19877:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224;translation factor#PC00223 DROME|FlyBase=FBgn0033907|UniProtKB=Q9V6Y3 Q9V6Y3 mRpS16 PTHR12919:SF41 30S RIBOSOMAL PROTEIN S16 SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 DROME|FlyBase=FBgn0053510|UniProtKB=Q59DY2 Q59DY2 Dmel\CG33510 PTHR11012:SF59 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0085312|UniProtKB=A8JR38 A8JR38 Dmel\CG34283 PTHR21402:SF5 GAMETOCYTE SPECIFIC FACTOR 1-RELATED GAMETOCYTE-SPECIFIC FACTOR 1 DROME|FlyBase=FBgn0260653|UniProtKB=Q9VW34 Q9VW34 serp PTHR45985:SF6 FAMILY NOT NAMED FI03450P DROME|FlyBase=FBgn0024250|UniProtKB=Q9XTN4 Q9XTN4 brk PTHR48233:SF5 MUCIN 4B, ISOFORM B-RELATED BRINKER DROME|FlyBase=FBgn0038850|UniProtKB=Q9VDF6 Q9VDF6 Jhbp15 PTHR11008:SF32 PROTEIN TAKEOUT-LIKE PROTEIN GH08336P-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035944|UniProtKB=Q8IQC1 Q8IQC1 CG5021 PTHR13019:SF25 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;macromolecule localization#GO:0033036;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;localization#GO:0051179;protein secretion#GO:0009306;secretion#GO:0046903;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0041626|UniProtKB=Q9I816 Q9I816 Or19a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039051|UniProtKB=Q9VCR0 Q9VCR0 Dmel\CG17109 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 DROME|FlyBase=FBgn0005427|UniProtKB=Q24312 Q24312 ewg PTHR20338:SF8 NUCLEAR RESPIRATORY FACTOR 1 NUCLEAR RESPIRATORY FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0030890|UniProtKB=Q9VWZ2 Q9VWZ2 Dmel\CG7536 PTHR10783:SF127 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED LD30826P-RELATED phosphate transmembrane transporter activity#GO:0005315;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;efflux transmembrane transporter activity#GO:0015562 phosphate ion transport#GO:0006817;export from cell#GO:0140352;homeostatic process#GO:0042592;cellular process#GO:0009987;cellular homeostasis#GO:0019725;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;chemical homeostasis#GO:0048878 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0264291|UniProtKB=Q9VEM2 Q9VEM2 Det PTHR46771:SF5 DETERIN DETERIN organelle organization#GO:0006996;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;chromosome segregation#GO:0007059;regulation of apoptotic process#GO:0042981;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cell cycle#GO:0007049;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell division#GO:0051301;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cytokinesis#GO:0000281;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;microtubule cytoskeleton organization#GO:0000226 membraneless organelle#GO:0043228;spindle#GO:0005819;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694 DROME|FlyBase=FBgn0028953|UniProtKB=Q6NR30 Q6NR30 BEST:LD13441 PTHR23022:SF119 TRANSPOSABLE ELEMENT-RELATED RE38958P viral or transposable element protein#PC00237 DROME|FlyBase=FBgn0039757|UniProtKB=Q9VA91 Q9VA91 RpS7 PTHR11278:SF0 40S RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN ES7 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;ribosome#GO:0005840;small-subunit processome#GO:0032040 ribosomal protein#PC00202 DROME|FlyBase=FBgn0005278|UniProtKB=P40320 P40320 Sams PTHR11964:SF1 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;nucleotidyltransferase#PC00174 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 DROME|FlyBase=FBgn0032819|UniProtKB=Q9VIS4 Q9VIS4 Dus3 PTHR45846:SF1 TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 RNA processing factor#PC00147 DROME|FlyBase=FBgn0038721|UniProtKB=A0A0B4JCY1 A0A0B4JCY1 subdued PTHR12308:SF83 ANOCTAMIN ANOCTAMIN intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0250906|UniProtKB=Q01604 Q01604 Pgk PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;kinase activity#GO:0016301;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;phosphoglycerate kinase activity#GO:0004618;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824 gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 DROME|FlyBase=FBgn0037254|UniProtKB=Q9VN30 Q9VN30 sac PTHR22878:SF74 DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED STERILE AFFECTING CILIOGENESIS DROME|FlyBase=FBgn0263782|UniProtKB=P14773 P14773 Hmgcr PTHR10572:SF24 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;isoprenoid metabolic process#GO:0006720 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;membrane#GO:0016020;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777 reductase#PC00198 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA reductase#P00491 DROME|FlyBase=FBgn0037590|UniProtKB=Q9VHQ7 Q9VHQ7 Or85b PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0033453|UniProtKB=A0A0B4LFY9 A0A0B4LFY9 Sting PTHR34339:SF2 STIMULATOR OF INTERFERON GENES PROTEIN STIMULATOR OF INTERFERON GENES PROTEIN HOMOLOG guanyl ribonucleotide binding#GO:0032561;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 macroautophagy#GO:0016236;response to other organism#GO:0051707;biological regulation#GO:0065007;reticulophagy#GO:0061709;regulation of metabolic process#GO:0019222;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;innate immune response#GO:0045087;defense response#GO:0006952;regulation of catabolic process#GO:0009894;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to external biotic stimulus#GO:0043207;vacuole organization#GO:0007033;organelle assembly#GO:0070925;defense response to other organism#GO:0098542;cellular component assembly#GO:0022607;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;organelle organization#GO:0006996;positive regulation of autophagy#GO:0010508;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;regulation of macroautophagy#GO:0016241;metabolic process#GO:0008152;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of macroautophagy#GO:0016239;cellular component organization#GO:0016043;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;process utilizing autophagic mechanism#GO:0061919;immune system process#GO:0002376 membrane#GO:0016020;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0260866|UniProtKB=A0A0B4KFY0 A0A0B4KFY0 dnr1 PTHR23280:SF13 4.1 G PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MYLIP catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0262475|UniProtKB=Q0E8R3 Q0E8R3 bru2 PTHR24012:SF877 RNA BINDING PROTEIN BRUNO 1, ISOFORM B-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030577|UniProtKB=Q9VY21 Q9VY21 Dmel\CG5334 PTHR11224:SF10 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0000489|UniProtKB=P16912 P16912 Pka-C3 PTHR24353:SF160 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell adhesion#GO:0007155;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862 DROME|FlyBase=FBgn0039943|UniProtKB=Q9W5Q1 Q9W5Q1 Dmel\CG17168 PTHR23308:SF36 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 SMAD NUCLEAR-INTERACTING PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 DROME|FlyBase=FBgn0025866|UniProtKB=Q9VT65 Q9VT65 CalpB PTHR10183:SF379 CALPAIN CALPAIN-A-RELATED protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 DROME|FlyBase=FBgn0038165|UniProtKB=Q9VFS9 Q9VFS9 Task6 PTHR11003:SF326 POTASSIUM CHANNEL, SUBFAMILY K ACID-SENSITIVE TWO PORE DOMAIN K+ CHANNEL DTASK-6 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0028411|UniProtKB=Q9V3H8 Q9V3H8 Nxt1 PTHR12612:SF9 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 2-RELATED macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0032911|UniProtKB=Q9I7L6 Q9I7L6 tadr PTHR43243:SF98 INNER MEMBRANE TRANSPORTER YGJI-RELATED TORN AND DIMINISHED RHABDOMERES, ISOFORM D transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 DROME|FlyBase=FBgn0031874|UniProtKB=Q9VM61 Q9VM61 Dmel\CG13775 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE DROME|FlyBase=FBgn0004635|UniProtKB=P20350 P20350 rho PTHR45840:SF2 RHOMBOID-RELATED PROTEIN PROTEIN RHOMBOID-RELATED DROME|FlyBase=FBgn0039495|UniProtKB=Q9VB66 Q9VB66 c-SP8 PTHR24260:SF147 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED DROME|FlyBase=FBgn0031597|UniProtKB=Q9VQY7 Q9VQY7 Dmel\CG17612 PTHR24390:SF278 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 772 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0029848|UniProtKB=Q9W430 Q9W430 Btnd PTHR10609:SF28 BIOTINIDASE-RELATED CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752 hydrolase#PC00121 DROME|FlyBase=FBgn0030099|UniProtKB=Q9W376 Q9W376 CG12056 PTHR10281:SF4 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUFERRICIN membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0033544|UniProtKB=A1Z8B5 A1Z8B5 Ube2W PTHR24068:SF153 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 W catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0051741|UniProtKB=Q9VJA7 Q9VJA7 Dmel\CG31741 PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI02050P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0052058|UniProtKB=Q8IQE2 Q8IQE2 Ir67c PTHR42643:SF39 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 56A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0027494|UniProtKB=Q9VB14 Q9VB14 RpS10a PTHR12146:SF0 40S RIBOSOMAL PROTEIN S10 RIBOSOMAL PROTEIN S10 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 DROME|FlyBase=FBgn0033427|UniProtKB=A1Z7W1 A1Z7W1 Smyd4-1 PTHR46165:SF8 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 DOWN AND OUT, ISOFORM A-RELATED histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0035132|UniProtKB=Q9W0R5 Q9W0R5 mthl10 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0004622|UniProtKB=P30975 P30975 TkR99D PTHR24238:SF72 G-PROTEIN COUPLED RECEPTOR TACHYKININ-LIKE PEPTIDES RECEPTOR 99D G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0035708|UniProtKB=A0A4D6K4X9 A0A4D6K4X9 axed PTHR45774:SF12 BTB/POZ DOMAIN-CONTAINING AXUNDEAD, ISOFORM F anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0036318|UniProtKB=Q9VU19 Q9VU19 Wbp2 PTHR31606:SF1 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN BINDING PROTEIN 2, ISOFORM E DNA binding#GO:0003677;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coactivator activity#GO:0003713;chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0003567|UniProtKB=P08970 P08970 su(Hw) PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0035251|UniProtKB=Q9W0B3 Q9W0B3 Vta1 PTHR46009:SF1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG establishment of localization in cell#GO:0051649;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;late endosome to vacuole transport#GO:0045324;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0035357|UniProtKB=Q0E8J0 Q0E8J0 MEP-1 PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0022153|UniProtKB=Q9VQZ1 Q9VQZ1 l(2)k05819 PTHR13219:SF6 TRANSMEMBRANE PROTEIN 94 TRANSMEMBRANE PROTEIN 94 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;magnesium ion transmembrane transporter activity#GO:0015095;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;magnesium ion transport#GO:0015693;intracellular transport#GO:0046907;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0005593|UniProtKB=P32100 P32100 RpL7 PTHR11524:SF16 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 DROME|FlyBase=FBgn0035918|UniProtKB=Q9VSM9 Q9VSM9 Cdc6 PTHR10763:SF26 CELL DIVISION CONTROL PROTEIN 6-RELATED DNA REPLICATION FACTOR CDC6 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 replication origin binding protein#PC00199 DROME|FlyBase=FBgn0261090|UniProtKB=Q9VUJ3 Q9VUJ3 Sytbeta PTHR10024:SF378 SYNAPTOTAGMIN SYNAPTOTAGMIN BETA, ISOFORM D SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299 transport#GO:0006810;localization#GO:0051179;regulation of secretion#GO:0051046;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0033597|UniProtKB=A1Z8H1 A1Z8H1 Cpr47Ea PTHR10380:SF222 CUTICLE PROTEIN CUTICULAR PROTEIN 47EA extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0267366|UniProtKB=Q9VAZ1 Q9VAZ1 mil PTHR11875:SF7 TESTIS-SPECIFIC Y-ENCODED PROTEIN AT14585P-RELATED binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0013972|UniProtKB=Q07093 Q07093 Gycalpha99B PTHR45655:SF6 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 HEAD-SPECIFIC GUANYLATE CYCLASE catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829;guanylate cyclase activity#GO:0004383 response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;response to oxygen levels#GO:0070482 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;catalytic complex#GO:1902494 guanylate cyclase#PC00114;cyclase#PC00079 DROME|FlyBase=FBgn0034467|UniProtKB=A1ZBP5 A1ZBP5 Dmel\CG15128 PTHR21391:SF0 AT04489P-RELATED AT04489P-RELATED DROME|FlyBase=FBgn0259707|UniProtKB=Q9W136 Q9W136 Dmel\CG42361 PTHR21174:SF0 FAMILY NOT NAMED HD PHOSPHOHYDROLASE FAMILY PROTEIN-RELATED DROME|FlyBase=FBgn0037040|UniProtKB=B7Z092 B7Z092 Dmel\CG12983 PTHR20929:SF12 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED AT08232P protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0035026|UniProtKB=Q9W147 Q9W147 Fcp1 PTHR23081:SF36 RNA POLYMERASE II CTD PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Transcription regulation by bZIP transcription factor#P00055>TFIIF#P01394;General transcription regulation#P00023>TFIIF#P00665 DROME|FlyBase=FBgn0031066|UniProtKB=Q9VWD1 Q9VWD1 COX6B PTHR11387:SF2 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidase#PC00175;oxidoreductase#PC00176 DROME|FlyBase=FBgn0039126|UniProtKB=Q9VCG3 Q9VCG3 CG13601 PTHR12499:SF30 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN neuromuscular process#GO:0050905;nervous system process#GO:0050877;system process#GO:0003008;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0262738|UniProtKB=P13217 P13217 norpA PTHR10336:SF36 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4 hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;establishment of localization#GO:0051234;lipid metabolic process#GO:0006629;transport#GO:0006810;phosphatidylinositol metabolic process#GO:0046488;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;organophosphate metabolic process#GO:0019637;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;metabolic process#GO:0008152;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209 phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Metabotropic glutamate receptor group I pathway#P00041>PLC#P01053;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Endothelin signaling pathway#P00019>PLCbeta#P00591;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PLC#P01068;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Wnt signaling pathway#P00057>Phospholipase C#P01443;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874 DROME|FlyBase=FBgn0086898|UniProtKB=Q7JUF2 Q7JUF2 dgo PTHR24203:SF95 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 6 ISOFORM X1-RELATED establishment or maintenance of cell polarity#GO:0007163;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 DROME|FlyBase=FBgn0051928|UniProtKB=Q9VQ11 Q9VQ11 Dmel\CG31928 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219 aspartic protease#PC00053;protease#PC00190 DROME|FlyBase=FBgn0037777|UniProtKB=Q9VH39 Q9VH39 NdufAF4 PTHR13338:SF4 UPF0240 PROTEIN NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 4 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0003545|UniProtKB=Q9V877 Q9V877 sub PTHR24115:SF1008 KINESIN-RELATED KINESIN-LIKE PROTEIN SUBITO binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0031333|UniProtKB=Q9VQ02 Q9VQ02 Dmel\CG5561 PTHR18901:SF48 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0004611|UniProtKB=P25455 P25455 Plc21C PTHR10336:SF149 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE CLASSES I AND II hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;transport#GO:0006810;establishment of localization#GO:0051234;organophosphate metabolic process#GO:0019637;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;signal transduction#GO:0007165;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 lipase#PC00143;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Endothelin signaling pathway#P00019>PLCbeta#P00591;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 DROME|FlyBase=FBgn0036366|UniProtKB=Q9VU77 Q9VU77 JMJD7 PTHR12461:SF99 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7 hydrolase activity#GO:0016787;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0052601|UniProtKB=B6VQA0 B6VQA0 betaNACtes3 PTHR10351:SF23 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036918|UniProtKB=Q9VW56 Q9VW56 Pfdn6 PTHR21431:SF0 PREFOLDIN SUBUNIT 6 PREFOLDIN SUBUNIT 6 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0033609|UniProtKB=Q494G8 Q494G8 Fbl6 PTHR13318:SF292 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6, ISOFORM A-RELATED protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 DROME|FlyBase=FBgn0039663|UniProtKB=Q9VAL2 Q9VAL2 Dmel\CG2321 PTHR13518:SF1 PUTATIVE TREBLE-CLEF ZINC-FINGER C2ORF42 FAMILY MEMBER RGD1306746 PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0028892|UniProtKB=Q9V3Z7 Q9V3Z7 BG:DS03023.2 PTHR12260:SF6 DAMAGE-CONTROL PHOSPHATASE ARMT1 DAMAGE-CONTROL PHOSPHATASE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0039464|UniProtKB=Q9VBA0 Q9VBA0 Dmel\CG6330 PTHR43691:SF11 URIDINE PHOSPHORYLASE FI09636P-RELATED cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 DROME|FlyBase=FBgn0000163|UniProtKB=Q0KHR3 Q0KHR3 baz PTHR16484:SF17 PARTITIONING DEFECTIVE 3 RELATED BAZOOKA, ISOFORM B ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;cell-cell junction#GO:0005911;apical plasma membrane#GO:0016324;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;cell junction#GO:0030054;apical part of cell#GO:0045177;apical junction complex#GO:0043296 DROME|FlyBase=FBgn0261995|UniProtKB=Q9VB64 Q9VB64 CG31063 PTHR11839:SF15 UDP/ADP-SUGAR PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139 metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196 DROME|FlyBase=FBgn0051116|UniProtKB=Q9VGH7 Q9VGH7 ClC-a PTHR45720:SF10 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 2 channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0002021|UniProtKB=Q9VJ10 Q9VJ10 l(2)37Bb PTHR13847:SF282 SARCOSINE DEHYDROGENASE-RELATED FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 HOMOLOG protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 DROME|FlyBase=FBgn0039189|UniProtKB=Q9VC87 Q9VC87 Dmel\CG18528 PTHR42714:SF9 TRNA MODIFICATION GTPASE GTPBP3 5-TAURINOMETHYLURIDINE-[TRNA] SYNTHASE SUBUNIT GTPB3, MITOCHONDRIAL nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0036255|UniProtKB=Q9VTU1 Q9VTU1 Atg12 PTHR13385:SF0 AUTOPHAGY PROTEIN 12 UBIQUITIN-LIKE PROTEIN ATG12 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;carbohydrate catabolic process#GO:0016052;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;piecemeal microautophagy of the nucleus#GO:0034727;protein-containing complex disassembly#GO:0032984;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056 transferase complex#GO:1990234;phagophore assembly site#GO:0000407;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0051635|UniProtKB=M9PCB8 M9PCB8 Dmel\CG31635 PTHR24112:SF66 LEUCINE-RICH REPEAT, ISOFORM F-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37 HOMOLOG biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;cell migration#GO:0016477;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of organelle organization#GO:0033043;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0003517|UniProtKB=P38979 P38979 sta PTHR11489:SF9 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;translation#GO:0006412;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 DROME|FlyBase=FBgn0261394|UniProtKB=P18053 P18053 Prosalpha3 PTHR11599:SF13 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-4 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 DROME|FlyBase=FBgn0261458|UniProtKB=Q9VPX6 Q9VPX6 capt PTHR10652:SF26 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN enzyme binding#GO:0019899;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 actin cytoskeleton organization#GO:0030036;cell morphogenesis#GO:0000902;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;developmental process#GO:0032502;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0033460|UniProtKB=A1Z813 A1Z813 Sec24AB PTHR13803:SF39 SEC24-RELATED PROTEIN SECRETORY 24AB, ISOFORM A protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;zinc ion binding#GO:0008270;SNARE binding#GO:0000149 intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;COPII-coated vesicle budding#GO:0090114;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043 ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0050090|UniProtKB=Q7JRM2 Q7JRM2 Erasp PTHR24260:SF151 AT07769P-RELATED EG:BACR7A4.3 PROTEIN-RELATED DROME|FlyBase=FBgn0050274|UniProtKB=Q8MMD7 Q8MMD7 CG13529 PTHR11547:SF15 ARGININE OR CREATINE KINASE ARGININE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 DROME|FlyBase=FBgn0000056|UniProtKB=P91615 P91615 Adhr PTHR44229:SF8 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] ALCOHOL DEHYDROGENASE-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0287844|UniProtKB=A0A0B4LH20 A0A0B4LH20 Dhc1 PTHR10676:SF344 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 5 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;microtubule motor activity#GO:0003777;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;outer dynein arm#GO:0036157;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0052311|UniProtKB=M9PBJ1 M9PBJ1 zormin PTHR13817:SF191 TITIN ZORMIN, ISOFORM J structural protein#PC00211 DROME|FlyBase=FBgn0053648|UniProtKB=Q2MGK1 Q2MGK1 Dmel\CG33648 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0034426|UniProtKB=A1ZBI6 A1ZBI6 AANATL5 PTHR20905:SF33 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0003459|UniProtKB=Q9VUE5 Q9VUE5 stwl PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0039448|UniProtKB=Q9VBC8 Q9VBC8 TwdlQ PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036974|UniProtKB=Q9VPH7 Q9VPH7 eRF1 PTHR10113:SF10 PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 translation factor activity#GO:0180051;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;translation#GO:0006412;translational termination#GO:0006415;protein-containing complex disassembly#GO:0032984;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation release factor#PC00225;translation factor#PC00223 DROME|FlyBase=FBgn0262732|UniProtKB=M9PFR6 M9PFR6 mbf1 PTHR10245:SF15 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 DROME|FlyBase=FBgn0033826|UniProtKB=A1Z9B8 A1Z9B8 Dmel\CG4734 PTHR33236:SF12 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0011300|UniProtKB=A1Z7L8 A1Z7L8 babo PTHR23255:SF71 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE BABO protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;signaling receptor activity#GO:0038023;activin binding#GO:0048185;kinase activity#GO:0016301;transferase activity#GO:0016740;molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824 biological regulation#GO:0065007;nervous system development#GO:0007399;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 serine/threonine protein kinase receptor#PC00205 Activin beta signaling pathway#P06210>BABO#P06231;MYO signaling pathway#P06215>BABO#P06310;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;ALP23B signaling pathway#P06209>BABO#P06220;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;BMP/activin signaling pathway-drosophila#P06211>TGFbetaR I#P06241;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442 DROME|FlyBase=FBgn0031194|UniProtKB=Q9VR62 Q9VR62 PP2C PTHR13832:SF354 PROTEIN PHOSPHATASE 2C GM14138P phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein phosphatase#PC00195 DROME|FlyBase=FBgn0033993|UniProtKB=Q4V3F5 Q4V3F5 Dmel\CG8089 PTHR24406:SF42 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED FI01110P-RELATED zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0039091|UniProtKB=Q9VCK9 Q9VCK9 Dmel\CG10182 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0037897|UniProtKB=Q9VGP1 Q9VGP1 Sptz PTHR46591:SF1 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 regulation of biological process#GO:0050789;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630 DROME|FlyBase=FBgn0266129|UniProtKB=P14083 P14083 lov PTHR23110:SF101 BTB DOMAIN TRANSCRIPTION FACTOR PROTEIN JIM LOVELL regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0031861|UniProtKB=Q9VM79 Q9VM79 Dmel\CG17375 PTHR20905:SF33 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038;transferase#PC00220 DROME|FlyBase=FBgn0031106|UniProtKB=Q9VR90 Q9VR90 Syx16 PTHR19957:SF83 SYNTAXIN SYNTAXIN-16 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 DROME|FlyBase=FBgn0016660|UniProtKB=Q94890 Q94890 H15 PTHR11267:SF212 T-BOX PROTEIN-RELATED LP04777P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;heart development#GO:0007507;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 DROME|FlyBase=FBgn0266099|UniProtKB=Q8IQN7 Q8IQN7 CG13036 PTHR14663:SF2 METHYLTRANSFERASE NSUN7-RELATED PROTEIN NSUN7 DROME|FlyBase=FBgn0038796|UniProtKB=Q9VDM6 Q9VDM6 eIF3g2 PTHR10352:SF88 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 DROME|FlyBase=FBgn0287775|UniProtKB=A1ZBR2 A1ZBR2 18w PTHR45617:SF95 LEUCINE RICH REPEAT FAMILY PROTEIN 18 WHEELER cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 DROME|FlyBase=FBgn0037395|UniProtKB=A0A0B4K600 A0A0B4K600 Dmel\CG10280 PTHR10127:SF859 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0038029|UniProtKB=B7Z0S9 B7Z0S9 GstD11 PTHR43969:SF2 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D11, ISOFORM B transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824 modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0030027|UniProtKB=Q9W3H0 Q9W3H0 SPH198 PTHR24258:SF146 SERINE PROTEASE-RELATED ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0036488|UniProtKB=Q9VUM2 Q9VUM2 Dmel\CG6878 PTHR28525:SF1 REACTIVE OXYGEN SPECIES MODULATOR 1 REACTIVE OXYGEN SPECIES MODULATOR 1 localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;membrane organization#GO:0061024;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrial protein import pathway#GO:7770058;mitochondrion organization#GO:0007005;protein import into mitochondrial matrix#GO:0030150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0033100|UniProtKB=Q8SYQ8 Q8SYQ8 Dmel\CG3420 PTHR46491:SF3 CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 DROME|FlyBase=FBgn0031170|UniProtKB=Q9VRG4 Q9VRG4 Abca3 PTHR19229:SF278 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0020620|UniProtKB=A1Z9K4 A1Z9K4 RN-tre PTHR22957:SF704 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN RELATED TO THE N TERMINUS OF TRE ONCOGENE, ISOFORM A enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0026432|UniProtKB=Q9VTS3 Q9VTS3 Grip163 PTHR19302:SF70 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 6 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0004638|UniProtKB=Q08012 Q08012 drk PTHR46037:SF1 PROTEIN ENHANCER OF SEVENLESS 2B GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 protein binding#GO:0005515;growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;cell communication#GO:0007154 cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COP9 signalosome#GO:0008180 FGF signaling pathway#P00021>Grb2#P00631;PI3 kinase pathway#P00048>Grb2#P01178;Angiogenesis#P00005>Grb2#P00234;Angiogenesis#P00005>Grb2#P00252;EGF receptor signaling pathway#P00018>Grb2#P00550;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Grb2#P00892;PDGF signaling pathway#P00047>Grb2#P01148 DROME|FlyBase=FBgn0085431|UniProtKB=A8JQY3 A8JQY3 Sol1 PTHR47537:SF2 CUBILIN SOL1, ISOFORM C plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0038125|UniProtKB=Q9VFY3 Q9VFY3 BcDNA:AT26376 PTHR12313:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0003076|UniProtKB=Q9VUY9 Q9VUY9 Pgm1 PTHR22573:SF2 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE 1 intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868;isomerase activity#GO:0016853 carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 mutase#PC00160;metabolite interconversion enzyme#PC00262;isomerase#PC00135 DROME|FlyBase=FBgn0085322|UniProtKB=A8JRE2 A8JRE2 Dmel\CG34293 PTHR28612:SF2 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031683|UniProtKB=M9PB41 M9PB41 Dmel\CG4230 PTHR14938:SF2 HCLS1-ASSOCIATED PROTEIN X-1 HCLS1-ASSOCIATED PROTEIN X-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 regulation of anatomical structure size#GO:0090066;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;response to peptide#GO:1901652;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament-based process#GO:0032970;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;regulation of supramolecular fiber organization#GO:1902903;cellular response to stimulus#GO:0051716;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794 apical part of cell#GO:0045177;endoplasmic reticulum#GO:0005783;cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136;membraneless organelle#GO:0043228;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;vesicle#GO:0031982;mitochondrion#GO:0005739;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0041629|UniProtKB=Q9W3C4 Q9W3C4 Hexo2 PTHR22600:SF42 BETA-HEXOSAMINIDASE BETA-N-ACETYLHEXOSAMINIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;cell periphery#GO:0071944;membrane#GO:0016020 glycosidase#PC00110 DROME|FlyBase=FBgn0062565|UniProtKB=Q8IRZ5 Q8IRZ5 Or19b PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030191|UniProtKB=Q9W2W2 Q9W2W2 Dmel\CG15306 PTHR10623:SF6 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER EB1, ISOFORM F-RELATED microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;cell cycle#GO:0007049;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;chromosome segregation#GO:0007059;protein localization to microtubule cytoskeleton#GO:0072698;cellular component assembly#GO:0022607;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;microtubule end#GO:1990752;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0027508|UniProtKB=Q9VBP3 Q9VBP3 Tnks PTHR24180:SF66 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824 localization#GO:0051179;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA metabolic process#GO:0051054;positive regulation of signal transduction#GO:0009967;regulation of telomere maintenance#GO:0032204;intracellular protein localization#GO:0008104;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of chromosome organization#GO:0033044;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;positive regulation of organelle organization#GO:0010638;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase inhibitor#PC00139;kinase modulator#PC00140 DROME|FlyBase=FBgn0037680|UniProtKB=Q9VHF5 Q9VHF5 pasi2 PTHR36694:SF4 PASIFLORA 1, ISOFORM A-RELATED LD42595P neurogenesis#GO:0022008;gliogenesis#GO:0042063;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;regulation of anatomical structure size#GO:0090066;nervous system development#GO:0007399;biological regulation#GO:0065007;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell junction organization#GO:0034330;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cell junction assembly#GO:0034329 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0015376|UniProtKB=Q8IQ05 Q8IQ05 cutlet PTHR23389:SF3 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0028741|UniProtKB=O96838 O96838 fab1 PTHR45748:SF7 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate biosynthetic process#GO:0090407;vacuole organization#GO:0007033;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506 kinase#PC00137;transferase#PC00220 DROME|FlyBase=FBgn0051184|UniProtKB=Q8IMX8 Q8IMX8 LSm3 PTHR13110:SF0 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 LSM3 HOMOLOG, U6 SMALL NUCLEAR RNA AND MRNA DEGRADATION ASSOCIATED nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 supramolecular complex#GO:0099080;U4/U6 x U5 tri-snRNP complex#GO:0046540;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;precatalytic spliceosome#GO:0071011;P-body#GO:0000932;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 DROME|FlyBase=FBgn0086693|UniProtKB=Q9W3W0 Q9W3W0 iav PTHR10582:SF41 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN INACTIVE channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0040964|UniProtKB=Q9VLF6 Q9VLF6 CG18661 PTHR20974:SF0 UPF0585 PROTEIN CG18661 UPF0585 PROTEIN CG18661 DROME|FlyBase=FBgn0003353|UniProtKB=Q7JPB9 Q7JPB9 sei PTHR10217:SF548 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL GH12235P passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;metal ion transport#GO:0030001;potassium ion transport#GO:0006813 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0036730|UniProtKB=Q9VVH7 Q9VVH7 qjt PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950;protein sumoylation#GO:0016925;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 DROME|FlyBase=FBgn0263260|UniProtKB=Q7JXF7 Q7JXF7 sel PTHR13341:SF2 MIR-INTERACTING SAPOSIN-LIKE PROTEIN PROTEIN SEELE enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0039339|UniProtKB=Q9VBQ7 Q9VBQ7 Dmel\CG5116 PTHR10229:SF0 GTP-BINDING PROTEIN HFLX GTP-BINDING PROTEIN 6-RELATED protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0052199|UniProtKB=Q9VVQ9 Q9VVQ9 Dmel\CG32199 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 oxidoreductase complex#GO:1990204;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0086906|UniProtKB=Q9I7U4 Q9I7U4 sls PTHR19890:SF10 FIBROBLAST GROWTH FACTOR RECEPTOR TITIN transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 DROME|FlyBase=FBgn0043533|UniProtKB=Q7KE32 Q7KE32 Obp56f PTHR11857:SF43 ODORANT BINDING PROTEIN-RELATED GEO07291P1-RELATED sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0036921|UniProtKB=Q9VW59 Q9VW59 RhoGDI PTHR10980:SF3 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 3 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0034168|UniProtKB=A1ZAL6 A1ZAL6 Dmel\CG15614 PTHR46641:SF25 FMRFAMIDE RECEPTOR-RELATED CNMAMIDE RECEPTOR-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0261934|UniProtKB=M9PEI6 M9PEI6 dikar PTHR14296:SF20 REMODELING AND SPACING FACTOR 1 DIKAR, ISOFORM F binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0050036|UniProtKB=A1Z8R4 A1Z8R4 CG8976 PTHR11214:SF314 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0030996|UniProtKB=Q9VWK7 Q9VWK7 Dmel\CG14194 PTHR13568:SF6 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 185B DROME|FlyBase=FBgn0038974|UniProtKB=Q9VD00 Q9VD00 Dmel\CG5377 PTHR46331:SF2 VALACYCLOVIR HYDROLASE SERINE HYDROLASE BPHL hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 DROME|FlyBase=FBgn0036998|UniProtKB=Q9VPE4 Q9VPE4 CG5969 PTHR31792:SF6 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 HOMOLOG cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0261041|UniProtKB=A0A0B4K866 A0A0B4K866 stj PTHR10166:SF63 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED STRAIGHTJACKET, ISOFORM C monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 transporter#PC00227;voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0037432|UniProtKB=Q9VI08 Q9VI08 BcDNA:GH28351 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 DROME|FlyBase=FBgn0036668|UniProtKB=Q9VVA9 Q9VVA9 Zcchc7 PTHR46543:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;tRNA metabolic process#GO:0006399;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;snRNA metabolic process#GO:0016073;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 DROME|FlyBase=FBgn0038453|UniProtKB=Q9VES1 Q9VES1 Arl6IP1 PTHR20952:SF0 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 1 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 DROME|FlyBase=FBgn0034939|UniProtKB=Q9W1F4 Q9W1F4 thoc5 PTHR13375:SF3 FMS INTERACTING PROTEIN THO COMPLEX SUBUNIT 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0266284|UniProtKB=Q9W590 Q9W590 Ns3 PTHR45709:SF6 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED LARGE SUBUNIT GTPASE 1 HOMOLOG hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0003463|UniProtKB=Q24025 Q24025 sog PTHR46526:SF1 CHORDIN CHORDIN cytokine binding#GO:0019955;protein binding#GO:0005515;binding#GO:0005488 anatomical structure development#GO:0048856;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;dorsal/ventral pattern formation#GO:0009953;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regionalization#GO:0003002;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of BMP signaling pathway#GO:0030510 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DPP signaling pathway#P06213>SOG#P06293;DPP-SCW signaling pathway#P06212>SOG#P06266;BMP/activin signaling pathway-drosophila#P06211>SOG#P06252;SCW signaling pathway#P06216>SOG#P06335 DROME|FlyBase=FBgn0035754|UniProtKB=Q9VS38 Q9VS38 MED4 PTHR13208:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0264294|UniProtKB=Q9V4N3 Q9V4N3 Cyt-b5 PTHR19359:SF14 CYTOCHROME B5 CYTOCHROME B5 tetrapyrrole binding#GO:0046906;binding#GO:0005488;heme binding#GO:0020037 membrane#GO:0016020;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 DROME|FlyBase=FBgn0037156|UniProtKB=Q9VNV2 Q9VNV2 Dmel\CG11523 PTHR12490:SF6 GSK3B-INTERACTING PROTEIN GEO05133P1-RELATED protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase A binding#GO:0051018;binding#GO:0005488 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0029771|UniProtKB=Q9W4B6 Q9W4B6 BcDNA:RE01432 PTHR22776:SF104 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01432P signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0040020|UniProtKB=Q9W5P1 Q9W5P1 MED21 PTHR13381:SF0 RNA POLYMERASE II HOLOENZYME COMPONENT SRB7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0285944|UniProtKB=P35500 P35500 para PTHR10037:SF288 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN PARA passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sensory perception#GO:0007600;nervous system process#GO:0050877;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;action potential#GO:0001508;sodium ion transport#GO:0006814;sensory perception of pain#GO:0019233;system process#GO:0003008;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0263980|UniProtKB=A0A0B4KEV7 A0A0B4KEV7 Stacl PTHR15135:SF7 STAC STAC-LIKE, ISOFORM J channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106 nervous system process#GO:0050877;neuromuscular process#GO:0050905;regulation of protein localization#GO:0032880;muscle system process#GO:0003012;regulation of biological process#GO:0050789;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;muscle contraction#GO:0006936;system process#GO:0003008;regulation of localization#GO:0032879;regulation of protein localization to membrane#GO:1905475;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 DROME|FlyBase=FBgn0039067|UniProtKB=Q9VCN9 Q9VCN9 wda PTHR19879:SF5 TRANSCRIPTION INITIATION FACTOR TFIID PROTEIN WILL DECREASE ACETYLATION structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;peptidase complex#GO:1905368;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;acetyltransferase complex#GO:1902493;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124 DROME|FlyBase=FBgn0038491|UniProtKB=Q9VEM0 Q9VEM0 Dmel\CG5292 PTHR11079:SF208 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE-34 DEAMINASE CATALYTIC SUBUNIT ADAT2 tRNA-specific adenosine deaminase activity#GO:0008251;hydrolase activity#GO:0016787;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;base conversion or substitution editing#GO:0016553;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;adenosine to inosine editing#GO:0006382;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121;deaminase#PC00088;metabolite interconversion enzyme#PC00262 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920;Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154 DROME|FlyBase=FBgn0025716|UniProtKB=Q7K012 Q7K012 Bap55 PTHR11937:SF596 ACTIN BRAHMA ASSOCIATED PROTEIN 55KD structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 DROME|FlyBase=FBgn0033969|UniProtKB=A1Z9V3 A1Z9V3 Pgm2b PTHR45745:SF1 PHOSPHOMANNOMUTASE 45A PHOSPHOGLUCOMUTASE 2A-RELATED isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound biosynthetic process#GO:0072522;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283;purine nucleoside metabolic process#GO:0042278;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521 isomerase#PC00135;metabolite interconversion enzyme#PC00262;mutase#PC00160 DROME|FlyBase=FBgn0011822|UniProtKB=Q9W5G3 Q9W5G3 Pgcl PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987 aspartic protease#PC00053;protease#PC00190 DROME|FlyBase=FBgn0086913|UniProtKB=Q9VP48 Q9VP48 Rab26 PTHR47978:SF21 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-26 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 small GTPase#PC00208 DROME|FlyBase=FBgn0040348|UniProtKB=Q9W5C1 Q9W5C1 Dmel\CG3703 PTHR22957:SF618 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN RE02292P enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0010770|UniProtKB=Q9VDE5 Q9VDE5 ppan PTHR12661:SF5 PETER PAN-RELATED SUPPRESSOR OF SWI4 1 HOMOLOG nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;binding#GO:0005488;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;preribosome, large subunit precursor#GO:0030687 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0025700|UniProtKB=Q9VL69 Q9VL69 CK01296 PTHR13399:SF2 TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT GAMMA organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0034583|UniProtKB=Q9W2M4 Q9W2M4 Dmel\CG10527 PTHR31649:SF1 AGAP009604-PA FARNESOIC ACID O-METHYL TRANSFERASE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0040290|UniProtKB=Q9VSE6 Q9VSE6 RecQ4 PTHR13710:SF108 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q4 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA helicase#PC00011 DROME|FlyBase=FBgn0083949|UniProtKB=Q0KIB0 Q0KIB0 side-III PTHR23278:SF26 SIDESTEP PROTEIN SIDESTEP III immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0037406|UniProtKB=Q9VNL8 Q9VNL8 Osi1 PTHR21879:SF26 FI03362P-RELATED-RELATED OSIRIS 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0037978|UniProtKB=Q9VGE5 Q9VGE5 KLHL18 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030716|UniProtKB=Q9VXK9 Q9VXK9 Cep164 PTHR21715:SF0 RH04127P CENTROSOMAL PROTEIN 164, ISOFORM A DROME|FlyBase=FBgn0027574|UniProtKB=Q8IMP6 Q8IMP6 CG5815 PTHR22691:SF8 YEAST SPT2-RELATED PROTEIN SPT2 HOMOLOG histone binding#GO:0042393;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;protein binding#GO:0005515 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription by RNA polymerase I#GO:0006360;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;RNA biosynthetic process#GO:0032774 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0053303|UniProtKB=Q76NQ0 Q76NQ0 Ost1 PTHR21049:SF0 RIBOPHORIN I DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0032809|UniProtKB=Q9VIT6 Q9VIT6 Fire PTHR15422:SF45 OS05G0565100 PROTEIN ASCORBATE FERRIREDUCTASE (TRANSMEMBRANE) DROME|FlyBase=FBgn0024326|UniProtKB=O61444 O61444 Mkk4 PTHR48013:SF15 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007 non-receptor serine/threonine protein kinase#PC00167 Huntington disease#P00029>SEK-1#P00792;Integrin signalling pathway#P00034>MEK#P00925;Apoptosis signaling pathway#P00006>SEK1#P00266;Angiogenesis#P00005>JNKK1#P00199;EGF receptor signaling pathway#P00018>MKK4,7#P00555;FGF signaling pathway#P00021>MKK4,7#P00637;Integrin signalling pathway#P00034>Jnk#P00951;Gonadotropin-releasing hormone receptor pathway#P06664>MKK4/7#P06760;FAS signaling pathway#P00020>MKK4#P00610;Ras Pathway#P04393>MKK4/7#P04565;p38 MAPK pathway#P05918>MKK4#P06034;Toll receptor signaling pathway#P00054>MKK4#P01366;Huntington disease#P00029>MAPKK4#P00787;Oxidative stress response#P00046>MKK4#P01138;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 DROME|FlyBase=FBgn0029761|UniProtKB=Q7KVW5 Q7KVW5 SK PTHR10153:SF44 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;binding#GO:0005488;gated channel activity#GO:0022836;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;calmodulin binding#GO:0005516;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;membrane#GO:0016020 ion channel#PC00133;voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0267698|UniProtKB=Q9VI13 Q9VI13 Pak PTHR48015:SF46 SERINE/THREONINE-PROTEIN KINASE TAO NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of developmental process#GO:0050793;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of cell projection organization#GO:0031344;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;response to stress#GO:0006950;response to nutrient levels#GO:0031667;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell migration#GO:0016477 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Angiogenesis#P00005>PAK#P00249;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 DROME|FlyBase=FBgn0035016|UniProtKB=Q9W158 Q9W158 Dmel\CG4612 PTHR24012:SF935 RNA BINDING PROTEIN LD36772P-RELATED RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytosol#GO:0005829;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034666|UniProtKB=Q7KVM3 Q7KVM3 SP20 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0027363|UniProtKB=Q9XTL2 Q9XTL2 Stam PTHR45929:SF3 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;endosomal transport#GO:0016197;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0053012|UniProtKB=A1Z8X9 A1Z8X9 Dmel\CG33012 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0039902|UniProtKB=Q9V4C6 Q9V4C6 Zip102B PTHR16133:SF0 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0027497|UniProtKB=Q9Y0Y6 Q9Y0Y6 Madm PTHR13902:SF67 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN HOMOLOG protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0031459|UniProtKB=Q8STA5 Q8STA5 HINT1 PTHR23089:SF55 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 nucleotide phosphatase#PC00173 DROME|FlyBase=FBgn0040340|UniProtKB=Q9W5C2 Q9W5C2 TRAM PTHR12371:SF11 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 DROME|FlyBase=FBgn0003091|UniProtKB=P05130 P05130 Pkc53E PTHR24356:SF390 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C, BRAIN ISOZYME-RELATED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKC#P00568;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;PDGF signaling pathway#P00047>PKC#P01150;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Apoptosis signaling pathway#P00006>PKCs#P00318;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565 DROME|FlyBase=FBgn0020392|UniProtKB=O61613 O61613 Nmt PTHR11377:SF5 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;localization within membrane#GO:0051668 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 DROME|FlyBase=FBgn0011335|UniProtKB=Q9VTT2 Q9VTT2 vers PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0036832|UniProtKB=Q9VVV0 Q9VVV0 Dmel\CG18223 PTHR24260:SF152 AT07769P-RELATED FI17609P1-RELATED DROME|FlyBase=FBgn0032376|UniProtKB=Q9VKF3 Q9VKF3 Tsp33B PTHR19282:SF521 TETRASPANIN AT12771P-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0020372|UniProtKB=A0A0B4KFZ4 A0A0B4KFZ4 TM4SF PTHR19282:SF505 TETRASPANIN TRANSMEMBRANE 4 SUPERFAMILY, ISOFORM C membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0033422|UniProtKB=Q9V589 Q9V589 Or45b PTHR21137:SF26 ODORANT RECEPTOR ODORANT RECEPTOR 10A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0020642|UniProtKB=P92181 P92181 Lcp65Ac PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0031054|UniProtKB=Q9VWE4 Q9VWE4 Ssu72 PTHR20383:SF9 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 DROME|FlyBase=FBgn0052671|UniProtKB=Q9VZ47 Q9VZ47 Rab9Fa PTHR47980:SF101 LD44762P IP08727P-RELATED establishment of localization#GO:0051234;endosomal transport#GO:0016197;exocytosis#GO:0006887;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;secretion by cell#GO:0032940;localization within membrane#GO:0051668;endocytic recycling#GO:0032456;export from cell#GO:0140352 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;trans-Golgi network transport vesicle#GO:0030140;intracellular organelle#GO:0043229;endosome#GO:0005768;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136 DROME|FlyBase=FBgn0004387|UniProtKB=Q9VB25 Q9VB25 Klp98A PTHR24115:SF400 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF16B cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887 vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0034052|UniProtKB=A1ZA64 A1ZA64 Dmel\CG8299 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0085303|UniProtKB=A2VEQ2 A2VEQ2 Dmel\CG34274 PTHR46540:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 12 TETRATRICOPEPTIDE REPEAT PROTEIN 12 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;spermatogenesis#GO:0007283;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;spermatid development#GO:0007286;sexual reproduction#GO:0019953 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 DROME|FlyBase=FBgn0035742|UniProtKB=Q9VS20 Q9VS20 Acbp4 PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0003996|UniProtKB=P10090 P10090 w PTHR48041:SF139 ABC TRANSPORTER G FAMILY MEMBER 28 PROTEIN WHITE active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0003206|UniProtKB=P04388 P04388 Ras64B PTHR24070:SF457 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE PROTEIN 2 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;establishment or maintenance of cell polarity#GO:0007163;Ras protein signal transduction#GO:0007265;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552 DROME|FlyBase=FBgn0004567|UniProtKB=P32031 P32031 slp2 PTHR46617:SF3 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0045485|UniProtKB=Q8INZ2 Q8INZ2 Gr36c PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0010803|UniProtKB=Q0KI98 Q0KI98 TrpRS PTHR10055:SF1 TRYPTOPHANYL-TRNA SYNTHETASE TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0016131|UniProtKB=Q7K306 Q7K306 Cdk4 PTHR24056:SF472 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0038339|UniProtKB=A8JR16 A8JR16 Dmel\CG6118 PTHR23110:SF84 BTB DOMAIN TRANSCRIPTION FACTOR BTB DOMAIN-CONTAINING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0035401|UniProtKB=Q9VZU8 Q9VZU8 Alg2 PTHR45918:SF1 ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2 ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0039043|UniProtKB=Q9VCR9 Q9VCR9 Dmel\CG17121 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 DROME|FlyBase=FBgn0027569|UniProtKB=Q9Y128 Q9Y128 cert PTHR22902:SF60 SESQUIPEDALIAN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0050390|UniProtKB=Q9W2I4 Q9W2I4 Sgf29 PTHR21539:SF0 SAGA-ASSOCIATED FACTOR 29 SAGA-ASSOCIATED FACTOR 29 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 DROME|FlyBase=FBgn0031377|UniProtKB=Q9VQ58 Q9VQ58 EMSY PTHR16500:SF3 BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036575|UniProtKB=Q9VUZ3 Q9VUZ3 firewood PTHR19359:SF164 CYTOCHROME B5 CYTOCHROME B5 TYPE B tetrapyrrole binding#GO:0046906;binding#GO:0005488;heme binding#GO:0020037 intracellular organelle#GO:0043229;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 DROME|FlyBase=FBgn0004629|UniProtKB=P23779 P23779 Cys PTHR12319:SF2 CYSTATIN-RELATED CYSTATIN-LIKE PROTEIN-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0015239|UniProtKB=Q24142 Q24142 Hr78 PTHR24083:SF54 NUCLEAR HORMONE RECEPTOR NUCLEAR HORMONE RECEPTOR HR78 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0031485|UniProtKB=Q9VQJ8 Q9VQJ8 Dmel\CG9643 PTHR12843:SF5 PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10 EEF1A LYSINE METHYLTRANSFERASE 2 lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0266666|UniProtKB=Q9VM46 Q9VM46 Sem1 PTHR16771:SF0 26 PROTEASOME COMPLEX SUBUNIT DSS1 26S PROTEASOME COMPLEX SUBUNIT SEM1 response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368;proteasome complex#GO:0000502;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0028658|UniProtKB=Q9V3R6 Q9V3R6 Adat1 PTHR10910:SF62 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN AT07585P-RELATED hydrolase activity#GO:0016787;RNA binding#GO:0003723;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;tRNA-specific adenosine deaminase activity#GO:0008251;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;adenosine to inosine editing#GO:0006382;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;base conversion or substitution editing#GO:0016553;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0034229|UniProtKB=A1ZAU4 A1ZAU4 CtsK2 PTHR12411:SF1051 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN F endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033785|UniProtKB=Q7JQL2 Q7JQL2 Sans PTHR24161:SF103 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED LD20463P protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034731|UniProtKB=Q9W249 Q9W249 cg10384 PTHR11208:SF140 RNA-BINDING PROTEIN RELATED GH05812P-RELATED RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 DROME|FlyBase=FBgn0264488|UniProtKB=M9PF73 M9PF73 CG6947 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0003268|UniProtKB=Q9V9W7 Q9V9W7 rod PTHR15688:SF1 KINETOCHORE-ASSOCIATED PROTEIN 1 KINETOCHORE-ASSOCIATED PROTEIN 1 enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;kinetochore assembly#GO:0051382;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic spindle assembly checkpoint signaling#GO:0007094;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;regulation of cell cycle process#GO:0010564;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;negative regulation of cell cycle#GO:0045786;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;organelle assembly#GO:0070925;negative regulation of chromosome organization#GO:2001251;organelle fission#GO:0048285;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;macromolecule localization#GO:0033036;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;intracellular protein localization#GO:0008104;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;negative regulation of mitotic nuclear division#GO:0045839;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;nuclear division#GO:0000280;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of chromosome segregation#GO:0051985;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;kinetochore organization#GO:0051383;regulation of mitotic sister chromatid segregation#GO:0033047;protein localization to kinetochore#GO:0034501;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047 condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;chromosome#GO:0005694;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle microtubule#GO:0005876;microtubule#GO:0005874;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 DROME|FlyBase=FBgn0035762|UniProtKB=Q9VS46 Q9VS46 Rint1 PTHR13520:SF0 RAD50-INTERACTING PROTEIN 1 RINT-1 RAD50-INTERACTING PROTEIN 1 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;endoplasmic reticulum protein-containing complex#GO:0140534;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0004406|UniProtKB=Q27607 Q27607 PolG1 PTHR10267:SF0 DNA POLYMERASE SUBUNIT GAMMA-1 DNA POLYMERASE SUBUNIT GAMMA-1 3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787 mitochondrial DNA metabolic process#GO:0032042;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260 intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739 DNA-directed DNA polymerase#PC00018 DROME|FlyBase=FBgn0027074|UniProtKB=Q9VJ47 Q9VJ47 Ugt36F1 PTHR48043:SF114 EG:EG0003.4 PROTEIN-RELATED IP04436P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740 DROME|FlyBase=FBgn0283503|UniProtKB=A0A1L4AAD6 A0A1L4AAD6 Neurl4 PTHR12429:SF14 NEURALIZED NEURALIZED-LIKE PROTEIN 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Neuralized#P01117 DROME|FlyBase=FBgn0035482|UniProtKB=Q9VZK1 Q9VZK1 Dmel\CG14985 PTHR21222:SF2 MIT DOMAIN-CONTAINING PROTEIN 1 FI11682P-RELATED DROME|FlyBase=FBgn0039783|UniProtKB=Q9VA61 Q9VA61 PH4alphaNE2 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034317|UniProtKB=A0A0B4KEZ3 A0A0B4KEZ3 CR14499 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0031663|UniProtKB=Q9VMW7 Q9VMW7 CG8891 PTHR11067:SF9 INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN INOSINE TRIPHOSPHATE PYROPHOSPHATASE hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787 metabolic process#GO:0008152;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;cellular process#GO:0009987;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotide phosphatase#PC00173 DROME|FlyBase=FBgn0033696|UniProtKB=Q9V675 Q9V675 Cyp6g2 PTHR24292:SF45 CYTOCHROME P450 CYTOCHROME P450 6G1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0011802|UniProtKB=Q9V3C4 Q9V3C4 Gem3 PTHR47958:SF89 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX20-RELATED macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;SMN complex#GO:0032797 RNA helicase#PC00032 DROME|FlyBase=FBgn0260959|UniProtKB=E1JH39 E1JH39 MCPH1 PTHR14625:SF3 MICROCEPHALIN MICROCEPHALIN mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle#GO:0007049 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0034761|UniProtKB=A0A0B4K8A8 A0A0B4K8A8 BcDNA:RH52355 PTHR23292:SF14 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16615P1-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;ion binding#GO:0043167 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0051342|UniProtKB=A8JQY9 A8JQY9 CG7472 PTHR12345:SF11 SYNTENIN RELATED FI13065P plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0014388|UniProtKB=O44783 O44783 sty PTHR12365:SF7 SPROUTY PROTEIN SPROUTY enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase inhibitor activity#GO:0019210;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of Ras protein signal transduction#GO:0046578;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>Spry#P00626;EGF receptor signaling pathway#P00018>Spry#P00541;EGF receptor signaling pathway#P00018>SPRY#G01511 DROME|FlyBase=FBgn0051469|UniProtKB=Q8ING6 Q8ING6 Argp PTHR11717:SF29 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE ARGININE PHOSPHATASE-RELATED hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195 DROME|FlyBase=FBgn0043025|UniProtKB=Q8IQR3 Q8IQR3 Adgf-A2 PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase metabolic process#GO:0009112;purine-containing compound catabolic process#GO:0072523;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase metabolic process#GO:0006144;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;nucleoside catabolic process#GO:0009164;purine nucleoside metabolic process#GO:0042278;purine-containing compound biosynthetic process#GO:0072522 cytosol#GO:0005829;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 deaminase#PC00088 DROME|FlyBase=FBgn0036210|UniProtKB=Q9VTP1 Q9VTP1 Dmel\CG14130 PTHR21052:SF0 SPERMATOGENESIS ASSOCIATED 11-RELATED RNA DEMETHYLASE ALKBH7, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 DROME|FlyBase=FBgn0287631|UniProtKB=A1ZAQ3 A1ZAQ3 CG15612 PTHR22826:SF209 RHO GUANINE EXCHANGE FACTOR-RELATED DH DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 DROME|FlyBase=FBgn0034352|UniProtKB=A1ZB91 A1ZB91 Dnaaf3 PTHR22118:SF14 DYNEIN ASSEMBLY FACTOR 3, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 3 cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925 chaperone#PC00072 DROME|FlyBase=FBgn0037734|UniProtKB=Q9VH90 Q9VH90 trbd PTHR13367:SF35 UBIQUITIN THIOESTERASE UBIQUITIN THIOESTERASE TRABID peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;positive regulation of canonical Wnt signaling pathway#GO:0090263;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;post-translational protein modification#GO:0043687;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 DROME|FlyBase=FBgn0034232|UniProtKB=Q7JZ53 Q7JZ53 mRpS4 PTHR11831:SF1 30S 40S RIBOSOMAL PROTEIN U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3 snoRNA binding#GO:0030515;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0026060|UniProtKB=Q9W438 Q9W438 Mipp2 PTHR20963:SF56 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0039827|UniProtKB=Q9VA02 Q9VA02 Oadh PTHR23152:SF38 2-OXOGLUTARATE DEHYDROGENASE 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152 oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036859|UniProtKB=Q9VVY0 Q9VVY0 Dmel\CG14085 PTHR33960:SF1 SIMILAR TO KIAA0825 PROTEIN KIAA0825 HOMOLOG DROME|FlyBase=FBgn0000454|UniProtKB=Q9VFQ9 Q9VFQ9 Dip-B PTHR11963:SF48 LEUCINE AMINOPEPTIDASE-RELATED DIPEPTIDASE B, ISOFORM A catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0030034|UniProtKB=Q9W3G1 Q9W3G1 Dmel\CG10555 PTHR23107:SF0 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN IP09280P transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 DROME|FlyBase=FBgn0034127|UniProtKB=Q7K3R0 Q7K3R0 Dmel\CG7848 PTHR23406:SF80 MALIC ENZYME-RELATED GH17657P-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidoreductase#PC00176 DROME|FlyBase=FBgn0037350|UniProtKB=Q9VNE8 Q9VNE8 Dph4 PTHR21454:SF49 DPH3 HOMOLOG-RELATED DIPHTHAMIDE BIOSYNTHESIS 4, ISOFORM A cation binding#GO:0043169;metal ion binding#GO:0046872;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 DROME|FlyBase=FBgn0029720|UniProtKB=Q9W4I0 Q9W4I0 Dmel\CG3009 PTHR12253:SF39 RH14732P PHOSPHOLIPASE A2 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787 DROME|FlyBase=FBgn0040959|UniProtKB=Q9VLL8 Q9VLL8 Peritrophin-15a PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0004643|UniProtKB=Q9W4X9 Q9W4X9 Zw10 PTHR12205:SF0 CENTROMERE/KINETOCHORE PROTEIN ZW10 CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG cellular component organization#GO:0016043;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic spindle assembly checkpoint signaling#GO:0007094;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;Golgi vesicle transport#GO:0048193;negative regulation of cell cycle#GO:0045786;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of chromosome organization#GO:2001251;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;organelle fission#GO:0048285;regulation of mitotic cell cycle#GO:0007346;mitotic sister chromatid segregation#GO:0000070;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;establishment of localization#GO:0051234;regulation of mitotic sister chromatid separation#GO:0010965;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;nuclear division#GO:0000280;cellular localization#GO:0051641;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;vesicle-mediated transport#GO:0016192;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;regulation of cellular process#GO:0050794;regulation of mitotic sister chromatid segregation#GO:0033047;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;chromosome organization#GO:0051276 kinetochore#GO:0000776;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;endoplasmic reticulum#GO:0005783;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;spindle#GO:0005819;endoplasmic reticulum protein-containing complex#GO:0140534;vesicle tethering complex#GO:0099023;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0038540|UniProtKB=Q9VEG3 Q9VEG3 Dmel\CG14321 PTHR35455:SF1 UNNAMED PRODUCT REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0029508|UniProtKB=Q7K1I4 Q7K1I4 Tsp42Ea PTHR19282:SF521 TETRASPANIN AT12771P-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0000221|UniProtKB=Q24157 Q24157 brn PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0024291|UniProtKB=Q9VK34 Q9VK34 Sirt1 PTHR11085:SF9 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 cellular response to stress#GO:0033554;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;constitutive heterochromatin formation#GO:0140719;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141 membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;organelle inner membrane#GO:0019866;nucleus#GO:0005634;chromatin#GO:0000785;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;organelle envelope#GO:0031967;chromosome#GO:0005694;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>SIRT-1#P04632 DROME|FlyBase=FBgn0051053|UniProtKB=Q8IMM9 Q8IMM9 nenya PTHR22663:SF17 RING FINGER PROTEIN NARYA-RELATED RING FINGER PROTEIN NARYA-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;organelle organization#GO:0006996;homologous chromosome pairing at meiosis#GO:0007129;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle#GO:0007049;reproductive process#GO:0022414;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285 condensed chromosome#GO:0000793;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;synaptonemal structure#GO:0099086;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0261803|UniProtKB=M9MS70 M9MS70 CG15785 PTHR21113:SF6 AGAP001705-PA CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0050375|UniProtKB=A1Z7D1 A1Z7D1 CG2280 PTHR24258:SF134 SERINE PROTEASE-RELATED SUBFAMILY NOT NAMED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0259145|UniProtKB=A0A4P7VAE4 A0A4P7VAE4 Dmel\CG42260 PTHR45638:SF4 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-3-RELATED ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;system process#GO:0003008;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ion channel#PC00133;ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0037751|UniProtKB=Q9VH70 Q9VH70 topi PTHR24390:SF285 ZINC FINGER PROTEIN TESTIS-SPECIFIC ZINC FINGER PROTEIN TOPI RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0053532|UniProtKB=Q59DY6 Q59DY6 lectin-37Da PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER VERSICAN CORE PROTEIN molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0011291|UniProtKB=P49906 P49906 Taf11 PTHR13218:SF8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 DROME|FlyBase=FBgn0035995|UniProtKB=Q9VSZ1 Q9VSZ1 DmTOM1 PTHR13856:SF137 VHS DOMAIN CONTAINING PROTEIN FAMILY GH05942P protein binding#GO:0005515;binding#GO:0005488;clathrin binding#GO:0030276 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0030492|UniProtKB=Q9VYC3 Q9VYC3 Dmel\CG15754 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0031726|UniProtKB=X2J9F6 X2J9F6 Cyp6a16 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0030077|UniProtKB=X2JD14 X2JD14 Dmel\CG15365 PTHR19354:SF2 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 DROME|FlyBase=FBgn0005596|UniProtKB=P25992 P25992 yem PTHR21669:SF28 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS YEMANUCLEIN cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0052831|UniProtKB=Q8IPA8 Q8IPA8 CG4831 PTHR21397:SF2 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED BPTF-ASSOCIATED CHROMATIN COMPLEX COMPONENT 1 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0028875|UniProtKB=A0A499GGQ3 A0A499GGQ3 nAChRalpha5 PTHR18945:SF926 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA5, ISOFORM I neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 transport#GO:0006810;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916 signaling receptor complex#GO:0043235;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 DROME|FlyBase=FBgn0051690|UniProtKB=Q9VQE9 Q9VQE9 Tmtc1 PTHR44216:SF3 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0040076|UniProtKB=P82891 P82891 primo-2 PTHR11717:SF7 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 DROME|FlyBase=FBgn0037843|UniProtKB=Q9VGV8 Q9VGV8 PhLP3 PTHR21148:SF11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0030668|UniProtKB=Q9VXR9 Q9VXR9 Dmel\CG8128 PTHR13994:SF13 NUDIX HYDROLASE RELATED FI03680P hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824 hydrolase#PC00121;nucleotide phosphatase#PC00173 DROME|FlyBase=FBgn0028577|UniProtKB=Q8T6B9 Q8T6B9 hfp PTHR47330:SF1 POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED POLY(U)-BINDING-SPLICING FACTOR PUF60 cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;alternative mRNA splicing, via spliceosome#GO:0000380;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of mRNA splicing, via spliceosome#GO:0048024;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0015286|UniProtKB=P48555 P48555 Rala PTHR24070:SF258 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-A catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 DROME|FlyBase=FBgn0029999|UniProtKB=Q9W3K4 Q9W3K4 Dmel\CG1575 PTHR16056:SF39 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN TESTIS-EXPRESSED PROTEIN 10 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0034835|UniProtKB=Q9W1T3 Q9W1T3 Dmel\CG3092 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;protein insertion into membrane#GO:0051205 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0035641|UniProtKB=Q9VRQ4 Q9VRQ4 Dmel\CG5568 PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 nucleoside phosphate biosynthetic process#GO:1901293;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521 ligase#PC00142 DROME|FlyBase=FBgn0283473|UniProtKB=Q9VWQ2 Q9VWQ2 S6KL PTHR24351:SF114 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE S6KL phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell communication#GO:0007154;TORC1 signaling#GO:0038202;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0038872|UniProtKB=Q86NP2 Q86NP2 Nelf-A PTHR13328:SF7 NEGATIVE ELONGATION FACTOR A NELF-A NEGATIVE ELONGATION FACTOR A negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0050431|UniProtKB=Q4V6Y7 Q4V6Y7 Dmel\CG30431 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0000559|UniProtKB=P13060 P13060 eEF2 PTHR42908:SF10 TRANSLATION ELONGATION FACTOR-RELATED EUKARYOTIC TRANSLATION ELONGATION FACTOR 2 translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904 translation elongation factor#PC00222 DROME|FlyBase=FBgn0031659|UniProtKB=Q9VMX1 Q9VMX1 CG14043 PTHR46321:SF1 KIF1-BINDING PROTEIN KIF-BINDING PROTEIN system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;neuron projection organization#GO:0106027;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039 DROME|FlyBase=FBgn0029690|UniProtKB=Q9W4N5 Q9W4N5 Dmel\CG6414 PTHR11559:SF395 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE esterase#PC00097 DROME|FlyBase=FBgn0035049|UniProtKB=Q9W122 Q9W122 Mmp1 PTHR10201:SF291 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE 1, ISOFORM C-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0036892|UniProtKB=Q7KUT2 Q7KUT2 Lon PTHR43718:SF2 LON PROTEASE LON PROTEASE HOMOLOG, MITOCHONDRIAL catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;DNA binding#GO:0003677 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;organelle organization#GO:0006996;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;mitochondrion organization#GO:0007005 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 DROME|FlyBase=FBgn0267384|UniProtKB=Q9VXE8 Q9VXE8 Ubc7 PTHR24067:SF154 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G2 catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>Ubc7#P01220 DROME|FlyBase=FBgn0043799|UniProtKB=Q8IMV0 Q8IMV0 BEST:LD10347 PTHR11088:SF89 TRNA DIMETHYLALLYLTRANSFERASE TRNA DIMETHYLALLYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 DROME|FlyBase=FBgn0037889|UniProtKB=Q9VGQ3 Q9VGQ3 scpr-A PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0015519|UniProtKB=Q9W3G6 Q9W3G6 nAChRalpha3 PTHR18945:SF895 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA3, ISOFORM B channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594 transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052 signaling receptor complex#GO:0043235;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 DROME|FlyBase=FBgn0039537|UniProtKB=Q9VB10 Q9VB10 Hsdl2 PTHR42808:SF3 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092 DROME|FlyBase=FBgn0263829|UniProtKB=Q0IGP7 Q0IGP7 CG9561 PTHR15481:SF0 RIBONUCLEIC ACID BINDING PROTEIN S1 LD23870P-RELATED macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0001967|UniProtKB=Q9VJU2 Q9VJU2 NimC3 PTHR24047:SF32 FI01909P-RELATED FI01909P-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035815|UniProtKB=E1JI63 E1JI63 Snmp2 PTHR11923:SF117 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 SENSORY NEURON MEMBRANE PROTEIN 2 cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 DROME|FlyBase=FBgn0038765|UniProtKB=Q9VDQ6 Q9VDQ6 Dmel\CG4424 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0037491|UniProtKB=Q9VI84 Q9VI84 Dmel\CG1227 PTHR22967:SF92 SERINE/THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0029963|UniProtKB=Q9W3P6 Q9W3P6 Dmel\CG10920 PTHR10780:SF18 MITOCHONDRIAL CARRIER HOMOLOG LD43650P molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0035027|UniProtKB=Q960Q8 Q960Q8 Dmel\CG3511 PTHR45625:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859 chaperone#PC00072 DROME|FlyBase=FBgn0034225|UniProtKB=Q7K0L5 Q7K0L5 veil PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824 purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine-containing compound catabolic process#GO:0072523 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 DROME|FlyBase=FBgn0283712|UniProtKB=Q8IR79 Q8IR79 LIMK1 PTHR46485:SF4 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0032499|UniProtKB=Q9VK07 Q9VK07 Uvrag PTHR15157:SF5 UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN process utilizing autophagic mechanism#GO:0061919;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;autophagy#GO:0006914;organophosphate metabolic process#GO:0019637 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;lytic vacuole#GO:0000323;extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234 DROME|FlyBase=FBgn0004597|UniProtKB=P25008 P25008 CycC PTHR10026:SF7 CYCLIN CYCLIN-C cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138;kinase modulator#PC00140 DROME|FlyBase=FBgn0052600|UniProtKB=Q9VY33 Q9VY33 dpr8 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253 DROME|FlyBase=FBgn0030777|UniProtKB=Q9VXC5 Q9VXC5 SPH161 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0004429|UniProtKB=P29615 P29615 LysP PTHR11407:SF63 LYSOZYME C LYSOZYME hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosidase#PC00110 DROME|FlyBase=FBgn0032850|UniProtKB=Q9V3B5 Q9V3B5 Kua PTHR48177:SF1 TRANSMEMBRANE PROTEIN 189 TRANSMEMBRANE PROTEIN 189 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0035936|UniProtKB=Q9V3E5 Q9V3E5 Tsp66E PTHR19282:SF544 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0029755|UniProtKB=Q9I7W5 Q9I7W5 Sas10 PTHR13237:SF8 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED SOMETHING ABOUT SILENCING PROTEIN 10 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0036150|UniProtKB=Q9VTH3 Q9VTH3 Ir68a PTHR42643:SF53 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 68A, ISOFORM A transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0031188|UniProtKB=Q9VR55 Q9VR55 CT34370 PTHR21377:SF1 PROTEIN FAM210B, MITOCHONDRIAL MITOCHONDRIAL INNER MEMBRANE SCAFFOLD 1 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0042105|UniProtKB=A8JQV1 A8JQV1 Dmel\CG18748 PTHR11188:SF167 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0032252|UniProtKB=Q9VKV3 Q9VKV3 loh PTHR13723:SF321 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE LONELY HEART, ISOFORM A catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0033887|UniProtKB=A1Z9J8 A1Z9J8 St4 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 DROME|FlyBase=FBgn0039472|UniProtKB=Q9VB92 Q9VB92 Dmel\CG17192 PTHR11610:SF178 LIPASE FI01825P-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0263593|UniProtKB=Q8SXP0 Q8SXP0 Lpin PTHR12181:SF73 LIPIN PHOSPHATIDATE PHOSPHATASE transcription regulator activity#GO:0140110;hydrolase activity#GO:0016787;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transcription coactivator activity#GO:0003713;phosphoric ester hydrolase activity#GO:0042578 response to hormone#GO:0009725;lipid catabolic process#GO:0016042;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;small molecule catabolic process#GO:0044282;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;fatty acid catabolic process#GO:0009062;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;carboxylic acid catabolic process#GO:0046395;positive regulation of cellular process#GO:0048522;glycerolipid biosynthetic process#GO:0045017;triglyceride biosynthetic process#GO:0019432;regulation of nucleobase-containing compound metabolic process#GO:0019219;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;cellular response to nitrogen compound#GO:1901699;positive regulation of DNA-templated transcription#GO:0045893;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;response to peptide hormone#GO:0043434;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;cellular response to insulin stimulus#GO:0032869;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid metabolic process#GO:0006638;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0035398|UniProtKB=Q9VZV2 Q9VZV2 Cht7 PTHR11177:SF409 CHITINASE CHITINASE 12-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;chitin metabolic process#GO:0006030;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0035131|UniProtKB=Q9W0R6 Q9W0R6 mthl9 PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0266053|UniProtKB=Q9VEN9 Q9VEN9 Patr-1 PTHR21551:SF0 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN ASSOCIATED WITH TOPO II RELATED - 1, ISOFORM A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mRNA catabolic process#GO:0006402;positive regulation of macromolecule metabolic process#GO:0010604;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;regulation of biological quality#GO:0065008;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;P-body assembly#GO:0033962;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component assembly#GO:0022607;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;nucleobase-containing compound metabolic process#GO:0006139;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;organelle assembly#GO:0070925 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0260487|UniProtKB=Q9VB40 Q9VB40 CG13980 PTHR24161:SF130 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED TRANSIENT RECEPTOR POTENTIAL CHANNEL PYREXIA protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0039664|UniProtKB=Q9VAL1 Q9VAL1 Dmel\CG2006 PTHR15627:SF8 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0031519|UniProtKB=Q9VQN8 Q9VQN8 Fign PTHR23074:SF17 AAA DOMAIN-CONTAINING FIDGETIN-LIKE PROTEIN 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037340|UniProtKB=Q9VND4 Q9VND4 Dmel\CG14671 PTHR31996:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA22 biological regulation#GO:0065007;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;vacuolar acidification#GO:0007035;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 DROME|FlyBase=FBgn0020622|UniProtKB=Q7KTZ2 Q7KTZ2 Pi3K21B PTHR10155:SF10 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PI3K21B, ISOFORM B kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane protein complex#GO:0098796;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 kinase modulator#PC00140 Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Angiogenesis#P00005>PI3K#P00236;VEGF signaling pathway#P00056>PI3K#P01413;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 DROME|FlyBase=FBgn0039085|UniProtKB=Q9VCL5 Q9VCL5 Ugt303B3 PTHR48043:SF145 EG:EG0003.4 PROTEIN-RELATED FI06409P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0052364|UniProtKB=Q8IQA2 Q8IQA2 tut PTHR21245:SF10 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN PROTEIN TUMOROUS TESTIS-RELATED RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0035285|UniProtKB=Q9W073 Q9W073 Dmel\CG12025 PTHR13558:SF1 TRANSMEMBRANE PROTEIN 134 TRANSMEMBRANE PROTEIN 134 DROME|FlyBase=FBgn0031997|UniProtKB=Q9VLR9 Q9VLR9 PGAP5 PTHR13315:SF0 METALLO PHOSPHOESTERASE RELATED METALLOPHOSPHOESTERASE 1 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 DROME|FlyBase=FBgn0052791|UniProtKB=Q9W4R3 Q9W4R3 DIP-alpha PTHR12231:SF255 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN ALPHA, ISOFORM A protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043 neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell junction#GO:0030054;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0002567|UniProtKB=A1Z7S3 A1Z7S3 Rab32 PTHR24073:SF1234 DRAB5-RELATED RAB32, ISOFORM B ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 DROME|FlyBase=FBgn0030065|UniProtKB=Q9W3B8 Q9W3B8 Dmel\CG12075 PTHR41148:SF1 LP09875P LP09875P DROME|FlyBase=FBgn0036072|UniProtKB=Q9VT84 Q9VT84 Dmel\CG6628 PTHR10334:SF457 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANTARES, ISOFORM B-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0010269|UniProtKB=Q24324 Q24324 Dsor1 PTHR48013:SF9 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MEK1-2#P00559;Endothelin signaling pathway#P00019>MEK#P00572;PDGF signaling pathway#P00047>MEK#P01162;FGF signaling pathway#P00021>MEK1-2#P00642;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 DROME|FlyBase=FBgn0037913|UniProtKB=Q8INK3 Q8INK3 fabp PTHR11955:SF135 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, MUSCLE small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 macromolecule localization#GO:0033036;lipid transport#GO:0006869;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0033204|UniProtKB=Q7JYX2 Q7JYX2 Dmel\CG2065 PTHR24320:SF294 RETINOL DEHYDROGENASE NADP-RETINOL DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;terpenoid metabolic process#GO:0006721;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0033631|UniProtKB=Q7JR71 Q7JR71 Sod3 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN]-RELATED oxidoreductase activity#GO:0016491;copper ion binding#GO:0005507;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular detoxification#GO:1990748;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302 oxidoreductase#PC00176 DROME|FlyBase=FBgn0051099|UniProtKB=Q8IMT2 Q8IMT2 CG10551 PTHR11012:SF6 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK DOMAIN OV1-RELATED DROME|FlyBase=FBgn0010197|UniProtKB=Q07553 Q07553 Gyc32E PTHR11920:SF516 GUANYLYL CYCLASE GUANYLATE CYCLASE 32E molecular transducer activity#GO:0060089;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653 response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;cell communication#GO:0007154;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanylate cyclase#PC00114;lyase#PC00144 DROME|FlyBase=FBgn0054040|UniProtKB=Q2PE19 Q2PE19 BP1015 PTHR21721:SF26 GH09876P-RELATED DUF753 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0032422|UniProtKB=Q9VK99 Q9VK99 atilla PTHR33562:SF15 ATILLA, ISOFORM B-RELATED-RELATED ATILLA, ISOFORM B-RELATED DROME|FlyBase=FBgn0036186|UniProtKB=Q9VTL4 Q9VTL4 Dmel\CG6071 PTHR11533:SF253 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0010387|UniProtKB=P42281 P42281 Acbp2 PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289 cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0035831|UniProtKB=Q9VSC6 Q9VSC6 Pop4 PTHR13348:SF0 RIBONUCLEASE P SUBUNIT P29 RIBONUCLEASE P PROTEIN SUBUNIT P29 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172 endoribonuclease#PC00094 DROME|FlyBase=FBgn0015247|UniProtKB=Q24307 Q24307 Diap2 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 enzyme regulator activity#GO:0030234;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of protein modification process#GO:0031399;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 DROME|FlyBase=FBgn0038429|UniProtKB=Q9VEV2 Q9VEV2 BcDNA:SD10961 PTHR43314:SF27 FAMILY NOT NAMED METHIONINE SYNTHASE REDUCTASE DROME|FlyBase=FBgn0261963|UniProtKB=Q9VMR2 Q9VMR2 mid PTHR11267:SF212 T-BOX PROTEIN-RELATED LP04777P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 multicellular organismal process#GO:0032501;heart development#GO:0007507;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;animal organ development#GO:0048513;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 DROME|FlyBase=FBgn0026876|UniProtKB=Q9XZS9 Q9XZS9 cg11403 PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA helicase#PC00011 DROME|FlyBase=FBgn0033363|UniProtKB=A1Z7M5 A1Z7M5 SP67 PTHR24253:SF63 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 DROME|FlyBase=FBgn0040506|UniProtKB=Q9VK50 Q9VK50 ACXE PTHR45627:SF12 ADENYLATE CYCLASE TYPE 1 ADENYLYL CYCLASE X E-RELATED adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 DROME|FlyBase=FBgn0036162|UniProtKB=Q9VTI5 Q9VTI5 Fum3 PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 DROME|FlyBase=FBgn0052202|UniProtKB=Q4V604 Q4V604 CG13381 PTHR35084:SF1 TCF3 FUSION PARTNER TCF3 FUSION PARTNER DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;apoptotic signaling pathway#GO:0097190;positive regulation of apoptotic process#GO:0043065;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;cell communication#GO:0007154 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0034500|UniProtKB=Q7K0F7 Q7K0F7 Ppdh PTHR24320:SF302 RETINOL DEHYDROGENASE CARBONYL REDUCTASE, ISOFORM A oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0033616|UniProtKB=Q7K3E9 Q7K3E9 CC8 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0001316|UniProtKB=Q9Y0E4 Q9Y0E4 klar PTHR21524:SF5 SPECTRIN REPEAT CONTAINING NUCLEAR ENVELOPE PROTEIN 2 NESPRIN-2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 establishment of organelle localization#GO:0051656;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;establishment of localization in cell#GO:0051649;nuclear migration#GO:0007097;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;nucleus organization#GO:0006997;establishment of localization#GO:0051234;intracellular transport#GO:0046907;organelle localization#GO:0051640;transport#GO:0006810 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0033569|UniProtKB=Q7JW60 Q7JW60 Dmel\CG12942 PTHR24379:SF141 KRAB AND ZINC FINGER DOMAIN-CONTAINING LD46263P binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0034283|UniProtKB=A1ZB12 A1ZB12 Dmel\CG14492 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0032729|UniProtKB=Q9VJ28 Q9VJ28 L2HGDH PTHR43104:SF2 L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 dehydrogenase#PC00092 DROME|FlyBase=FBgn0003575|UniProtKB=P22293 P22293 su(sable) PTHR13119:SF12 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI PROTEIN SUPPRESSOR OF SABLE DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription elongation#GO:0032784;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0290170|UniProtKB=Q9VXH6 Q9VXH6 CalpC PTHR10183:SF394 CALPAIN CALPAIN-C peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 DROME|FlyBase=FBgn0250791|UniProtKB=Q23983 Q23983 alphaSnap PTHR13768:SF8 SOLUBLE NSF ATTACHMENT PROTEIN SNAP ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;cellular component disassembly#GO:0022411;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0051370|UniProtKB=Q9VBS8 Q9VBS8 Dmel\CG31370 PTHR11012:SF12 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0004896|UniProtKB=Q02361 Q02361 fd59A PTHR11829:SF402 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD3-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0040607|UniProtKB=Q9VBC3 Q9VBC3 Dmel\CG14244 PTHR20987:SF0 CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0030503|UniProtKB=Q9VYA8 Q9VYA8 Tango2 PTHR17985:SF28 SER/THR-RICH PROTEIN T10 IN DGCR REGION TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;endomembrane system organization#GO:0010256;secretion#GO:0046903;protein secretion#GO:0009306;localization#GO:0051179;protein transport#GO:0015031;secretion by cell#GO:0032940;cellular component organization#GO:0016043;protein localization to extracellular region#GO:0071692;Golgi organization#GO:0007030;export from cell#GO:0140352 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 DROME|FlyBase=FBgn0285955|UniProtKB=A8JR05 A8JR05 cv-c PTHR12659:SF7 RHO-TYPE GTPASE ACTIVATING PROTEIN CROSSVEINLESS C, ISOFORM C molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;organelle organization#GO:0006996;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;regulation of intracellular signal transduction#GO:1902531;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;actin cytoskeleton organization#GO:0030036;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 GTPase-activating protein#PC00257;G-protein modulator#PC00022 DROME|FlyBase=FBgn0001321|UniProtKB=Q9VH23 Q9VH23 knk PTHR24036:SF16 SKELETOR-RELATED KNICKKOPF transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0085386|UniProtKB=A0A4D6K026 A0A4D6K026 Gucy2d PTHR11920:SF462 GUANYLYL CYCLASE GUANYLATE CYCLASE molecular transducer activity#GO:0060089;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653 nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanylate cyclase#PC00114;lyase#PC00144 DROME|FlyBase=FBgn0035876|UniProtKB=Q9VSH8 Q9VSH8 Pex2 PTHR23350:SF4 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 2 chaperone#PC00072 DROME|FlyBase=FBgn0039532|UniProtKB=Q7JWS8 Q7JWS8 Mtl PTHR24072:SF399 RHO FAMILY GTPASE AT17867P protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cortical cytoskeleton organization#GO:0030865;regulation of developmental process#GO:0050793;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;Rac protein signal transduction#GO:0016601;generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163;signaling#GO:0023052;cell projection organization#GO:0030030;cell differentiation#GO:0030154;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cell projection assembly#GO:0030031;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737 G-protein#PC00020;small GTPase#PC00208 Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;FGF signaling pathway#P00021>Rac#P00645 DROME|FlyBase=FBgn0038149|UniProtKB=Q95RA9 Q95RA9 GILT1 PTHR13234:SF69 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0032369|UniProtKB=Q9VKG0 Q9VKG0 Dmel\CG6614 PTHR44314:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 cilium#GO:0005929;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 DROME|FlyBase=FBgn0028704|UniProtKB=Q9U6A0 Q9U6A0 Nckx30C PTHR10846:SF72 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER NCKX30C active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0029134|UniProtKB=Q7K148 Q7K148 Prosbeta5 PTHR11599:SF246 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0030766|UniProtKB=Q9VXD9 Q9VXD9 mthl1 PTHR46953:SF4 G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0085440|UniProtKB=X2JJX6 X2JJX6 Lgr4 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G PROTEIN-COUPLED RECEPTOR 4, ISOFORM C transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039697|UniProtKB=Q0KHZ6 Q0KHZ6 Etfb PTHR21294:SF8 ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0053783|UniProtKB=Q4AB36 Q4AB36 Dmel\CG33783 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0030791|UniProtKB=Q9VXB0 Q9VXB0 CG9132 PTHR12847:SF9 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED NECAP-LIKE PROTEIN CG9132 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0001965|UniProtKB=P26675 P26675 Sos PTHR23113:SF363 GUANINE NUCLEOTIDE EXCHANGE FACTOR PROTEIN SON OF SEVENLESS nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>SOS#P04552;Integrin signalling pathway#P00034>SOS#P00920;PDGF signaling pathway#P00047>SOS#P01159;EGF receptor signaling pathway#P00018>SOS#P00558;Angiogenesis#P00005>SOS-1#P00193;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883;FGF signaling pathway#P00021>SOS#P00641 DROME|FlyBase=FBgn0051676|UniProtKB=Q9VII5 Q9VII5 Dmel\CG31676 PTHR33562:SF32 ATILLA, ISOFORM B-RELATED-RELATED GEO08323P1-RELATED DROME|FlyBase=FBgn0028886|UniProtKB=Q9VJR4 Q9VJR4 Dmel\CG15279 PTHR11616:SF339 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943 glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 DROME|FlyBase=FBgn0015663|UniProtKB=Q9VQT0 Q9VQT0 Ugt36A1 PTHR48043:SF114 EG:EG0003.4 PROTEIN-RELATED IP04436P-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 DROME|FlyBase=FBgn0002577|UniProtKB=Q9VYU8 Q9VYU8 m PTHR46560:SF14 CYPHER, ISOFORM B MINIATURE developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell morphogenesis#GO:0000902 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0038861|UniProtKB=Q9VDD9 Q9VDD9 Trm7-34 PTHR10920:SF12 RIBOSOMAL RNA METHYLTRANSFERASE TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA methyltransferase#PC00033 DROME|FlyBase=FBgn0037618|UniProtKB=Q9VHM6 Q9VHM6 Ouib PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0013799|UniProtKB=Q24180 Q24180 Deaf1 PTHR10237:SF15 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0026741|UniProtKB=Q7JVK1 Q7JVK1 mRpL18 PTHR12899:SF23 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843 macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleic acid transport#GO:0050657 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0031590|UniProtKB=Q9VQX6 Q9VQX6 Dmel\CG3702 PTHR21347:SF14 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0004397|UniProtKB=O46037 O46037 Vinc PTHR46180:SF1 VINCULIN VINCULIN protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987 membraneless organelle#GO:0043228;cell junction#GO:0030054;cell-cell contact zone#GO:0044291;adherens junction#GO:0005912;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 Gonadotropin-releasing hormone receptor pathway#P06664>Vinculin#P06771;Integrin signalling pathway#P00034>Vinculin#P00937 DROME|FlyBase=FBgn0033883|UniProtKB=Q9V6U9 Q9V6U9 Mecr PTHR43981:SF2 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 reductase#PC00198;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0030100|UniProtKB=Q9I7W2 Q9I7W2 Dmel\CG12106 PTHR31159:SF1 COMM DOMAIN-CONTAINING PROTEIN 3 COMM DOMAIN-CONTAINING PROTEIN 3 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0027835|UniProtKB=Q7KN75 Q7KN75 Dp1 PTHR10627:SF31 SCP160 DODECA-SATELLITE-BINDING PROTEIN 1, ISOFORM A binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0030687|UniProtKB=A8JUY3 A8JUY3 Polr3A PTHR19376:SF72 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1 nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0027565|UniProtKB=Q9Y124 Q9Y124 BcDNA.GH08385 PTHR22761:SF10 CHARGED MULTIVESICULAR BODY PROTEIN BCDNA.GH08385-RELATED localization#GO:0051179;cellular localization#GO:0051641;membrane assembly#GO:0071709;cellular component organization#GO:0016043;late endosome to vacuole transport#GO:0045324;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;nuclear membrane organization#GO:0071763;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192 vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic side of membrane#GO:0098562;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;cytoplasmic side of plasma membrane#GO:0009898;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0039058|UniProtKB=Q9VCQ3 Q9VCQ3 VhaAC39-2 PTHR11028:SF6 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular transport#GO:0046907;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar transport#GO:0007034;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453 ATPase dependent transmembrane transport complex#GO:0098533;early endosome#GO:0005769;endosome#GO:0005768;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;transporter complex#GO:1990351;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;endomembrane system#GO:0012505;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP synthase#PC00002 DROME|FlyBase=FBgn0030761|UniProtKB=M9PHS8 M9PHS8 Dmel\CG9784 PTHR11200:SF310 INOSITOL 5-PHOSPHATASE LD06095P hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;ruffle#GO:0001726;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 DROME|FlyBase=FBgn0011708|UniProtKB=Q24509 Q24509 Syx5 PTHR19957:SF3 SYNTAXIN SYNTAXIN-5 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 SNARE protein#PC00034 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091 DROME|FlyBase=FBgn0025630|UniProtKB=O77264 O77264 Rtca PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE cyclase activity#GO:0009975;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031550|UniProtKB=Q9VQS5 Q9VQS5 IFT57 PTHR16011:SF0 IFT57/HIPPI INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;non-motile cilium assembly#GO:1905515;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271 intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 structural protein#PC00211 Huntington disease#P00029>Hip-12#P00763;Huntington disease#P00029>Hippi#P00794 DROME|FlyBase=FBgn0036528|UniProtKB=Q8IA41 Q8IA41 pgant11 PTHR11675:SF134 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0052405|UniProtKB=Q8I0P8 Q8I0P8 Cpr65Av PTHR10380:SF218 CUTICLE PROTEIN CUTICLE PROTEIN DCP2-RELATED extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0024887|UniProtKB=Q9VPH4 Q9VPH4 kin17 PTHR12805:SF0 KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG DNA_RNA-BINDING PROTEIN KIN17 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0030359|UniProtKB=Q9VYR5 Q9VYR5 Dmel\CG18130 PTHR46135:SF3 NME/NM23 FAMILY MEMBER 8 NME_NM23 FAMILY MEMBER 8 DROME|FlyBase=FBgn0035589|UniProtKB=Q9VRJ5 Q9VRJ5 CHMP2B PTHR10476:SF40 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2B membrane traffic protein#PC00150 DROME|FlyBase=FBgn0022160|UniProtKB=Q7K569 Q7K569 Gpo1 PTHR11985:SF15 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092 DROME|FlyBase=FBgn0037027|UniProtKB=Q9VPB0 Q9VPB0 HIPP1 PTHR11941:SF179 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE, MITOCHONDRIAL monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0290419|UniProtKB=Q9VBG4 Q9VBG4 Dmel\CG12290 PTHR24248:SF190 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GH12381P signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0053233|UniProtKB=Q86NP5 Q86NP5 CG12036 PTHR24064:SF445 SOLUTE CARRIER FAMILY 22 MEMBER AT15560P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0260972|UniProtKB=A1Z7Q8 A1Z7Q8 alc PTHR10343:SF84 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein-binding activity modulator#PC00095;kinase modulator#PC00140 DROME|FlyBase=FBgn0035833|UniProtKB=Q9VSC9 Q9VSC9 Dmel\CG7565 PTHR46182:SF2 FI19480P1 FI19480P1 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;developmental process#GO:0032502;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;system development#GO:0048731;neurogenesis#GO:0022008;cellular process#GO:0009987;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cell motility#GO:0048870;nervous system development#GO:0007399 intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 DROME|FlyBase=FBgn0036796|UniProtKB=Q9VVQ7 Q9VVQ7 Dmel\CG18231 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213 endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0037930|UniProtKB=Q9VGK3 Q9VGK3 Dmel\CG14715 PTHR45779:SF7 PEPTIDYLPROLYL ISOMERASE PEPTIDYLPROLYL ISOMERASE catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 DROME|FlyBase=FBgn0030545|UniProtKB=Q9VY55 Q9VY55 BcDNA:GM24986 PTHR23419:SF8 DIVALENT CATION TOLERANCE CUTA-RELATED FI09726P cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;copper ion binding#GO:0005507;binding#GO:0005488 primary active transporter#PC00068 DROME|FlyBase=FBgn0014868|UniProtKB=Q24319 Q24319 Ost48 PTHR10830:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0020910|UniProtKB=O16797 O16797 RpL3 PTHR11363:SF5 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0034057|UniProtKB=Q7K3T4 Q7K3T4 anon-WO0118547.93 PTHR22883:SF40 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;protein targeting#GO:0006605;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein targeting to membrane#GO:0006612;protein localization to cell periphery#GO:1990778;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0021800|UniProtKB=Q8MRQ2 Q8MRQ2 Reph PTHR41142:SF1 SI:DKEY-16J16.4 SI:DKEY-16J16.4 nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;peripheral nervous system development#GO:0007422;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108 DROME|FlyBase=FBgn0020379|UniProtKB=A0A0B4K653 A0A0B4K653 Rfx PTHR12619:SF5 RFX TRANSCRIPTION FACTOR FAMILY RFX, ISOFORM H RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0033027|UniProtKB=Q7K860 Q7K860 TpnC4 PTHR23050:SF221 CALCIUM BINDING PROTEIN FI07231P-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061;calcium-binding protein#PC00060 DROME|FlyBase=FBgn0038385|UniProtKB=Q9VF10 Q9VF10 Fbxl7 PTHR13318:SF50 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 7 DROME|FlyBase=FBgn0036886|UniProtKB=Q9VW10 Q9VW10 Dmel\CG9300 PTHR15633:SF2 NUCLEOLAR PROTEIN 11 NUCLEOLAR PROTEIN 11 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0032465|UniProtKB=Q9VK46 Q9VK46 Yip1d1 PTHR21236:SF2 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF vesicle fusion#GO:0006906;cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;membrane fusion#GO:0061025;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 structural protein#PC00211 DROME|FlyBase=FBgn0051729|UniProtKB=Q9VK06 Q9VK06 CG6263 PTHR24092:SF5 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;macromolecule localization#GO:0033036;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;Golgi vesicle transport#GO:0048193;transport#GO:0006810;endocytosis#GO:0006897;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876 endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0058263|UniProtKB=Q494G7 Q494G7 MFS17 PTHR11662:SF77 SOLUTE CARRIER FAMILY 17 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 17, ISOFORM F transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0067622|UniProtKB=Q76NP9 Q76NP9 LSm-4 PTHR15666:SF1 COMM DOMAIN CONTAINING PROTEIN 5 COMM DOMAIN-CONTAINING PROTEIN 5 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0053723|UniProtKB=Q4ABG8 Q4ABG8 Dmel\CG33723 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0036249|UniProtKB=A0A0S0WNE9 A0A0S0WNE9 Dmel\CG11560 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DROME|FlyBase=FBgn0010747|UniProtKB=Q9V3D9 Q9V3D9 Srp54k PTHR11564:SF40 SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54 hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;signal sequence receptor activity#GO:0005048;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein transmembrane transport#GO:0071806;transport#GO:0006810;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;intracellular protein transport#GO:0006886;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein targeting#GO:0006605;localization within membrane#GO:0051668;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0069056|UniProtKB=Q7KVM8 Q7KVM8 Dmel\CG33226 PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 DROME|FlyBase=FBgn0036569|UniProtKB=Q9VUY4 Q9VUY4 IleRS-m PTHR42765:SF3 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0038539|UniProtKB=Q9VEG5 Q9VEG5 Atg8b PTHR10969:SF33 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;GABA receptor binding#GO:0050811;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840 vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;autophagosome#GO:0005776;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0039993|UniProtKB=Q7PLE6 Q7PLE6 Bckdhb PTHR42980:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL oxidoreductase complex#GO:1990204;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0051327|UniProtKB=Q8ING1 Q8ING1 Dmel\CG31327 PTHR39079:SF1 FI08034P-RELATED GH11706P-RELATED DROME|FlyBase=FBgn0032079|UniProtKB=A8DYY1 A8DYY1 CG9524 PTHR39077:SF2 DUF4793 DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE APD1-4 MIDDLE DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0053110|UniProtKB=Q9VCY5 Q9VCY5 CG13844 PTHR11157:SF22 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 DROME|FlyBase=FBgn0036224|UniProtKB=Q9VTQ9 Q9VTQ9 Rpt4R PTHR23073:SF31 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 10B macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to endoplasmic reticulum stress#GO:0034976;regulation of RNA metabolic process#GO:0051252;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of DNA-templated transcription initiation#GO:2000142;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;positive regulation of cellular component biogenesis#GO:0044089;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0260470|UniProtKB=Q9VMV3 Q9VMV3 SP555 PTHR12245:SF12 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0052283|UniProtKB=Q8IRD7 Q8IRD7 Drsl3 PTHR33147:SF98 DEFENSIN-LIKE PROTEIN 1 DRO1 PROTEIN-RELATED defense response#GO:0006952;response to stimulus#GO:0050896;response to stress#GO:0006950 antimicrobial response protein#PC00051 DROME|FlyBase=FBgn0003748|UniProtKB=Q9W2M2 Q9W2M2 Treh PTHR23403:SF26 TREHALASE TREHALASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate metabolic process#GO:0005975;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152 DROME|FlyBase=FBgn0053653|UniProtKB=Q9NHE5 Q9NHE5 Cadps PTHR12166:SF8 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 DROME|FlyBase=FBgn0031875|UniProtKB=Q9VM60 Q9VM60 CG3430 PTHR13489:SF0 MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 DROME|FlyBase=FBgn0035715|UniProtKB=Q9VRY6 Q9VRY6 Ist1 PTHR12161:SF5 IST1 FAMILY MEMBER IST1 HOMOLOG macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179 DROME|FlyBase=FBgn0033524|UniProtKB=Q9V5L3 Q9V5L3 Cyp49a1 PTHR24305:SF28 CYTOCHROME P450 CYTOCHROME P450 49A1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0014342|UniProtKB=Q9VND0 Q9VND0 mia PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP#P00670;General transcription regulation#P00023>TBP-associated factors#P00658 DROME|FlyBase=FBgn0038369|UniProtKB=Q9VF28 Q9VF28 Arpc3A PTHR12391:SF0 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Integrin signalling pathway#P00034>Arp2/3#P00912;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 DROME|FlyBase=FBgn0031745|UniProtKB=Q9VML8 Q9VML8 rau PTHR21298:SF2 GH01721P GH01721P positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of response to stimulus#GO:0048583 DROME|FlyBase=FBgn0039651|UniProtKB=Q9VAM8 Q9VAM8 Cyt-c1L PTHR10266:SF3 CYTOCHROME C1 CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679 mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Huntington disease#P00029>Cytochrome c#P00785;FAS signaling pathway#P00020>CytochromeC#P00620;ATP synthesis#P02721>Cyt bc1#P02799 DROME|FlyBase=FBgn0032891|UniProtKB=Q9VII8 Q9VII8 Oseg5 PTHR24098:SF0 OUTER SEGMENT 5 OUTER SEGMENT 5 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 membrane-bounded organelle#GO:0043227;intraciliary transport particle B#GO:0030992;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DROME|FlyBase=FBgn0262513|UniProtKB=A1ZAL7 A1ZAL7 Vha16-4 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 DROME|FlyBase=FBgn0261514|UniProtKB=Q8IP58 Q8IP58 NimA PTHR24052:SF8 DELTA-RELATED NIMROD A, ISOFORM E membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0267336|UniProtKB=A0A0B4KFN3 A0A0B4KFN3 Glut4EF PTHR13006:SF9 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 GLUCOSE TRANSPORTER 4 ENHANCER FACTOR, ISOFORM G sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 DROME|FlyBase=FBgn0003149|UniProtKB=P35415 P35415 Prm PTHR22988:SF77 MYOTONIC DYSTROPHY S/T KINASE-RELATED PARAMYOSIN, LONG FORM catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of biological quality#GO:0065008;actin filament-based process#GO:0030029;regulation of actin filament length#GO:0030832;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cell cycle#GO:0007049;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0020762|UniProtKB=Q9VQY4 Q9VQY4 Atet PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0015040|UniProtKB=Q9W130 Q9W130 Cyp9c1 PTHR24292:SF54 CYTOCHROME P450 CYTOCHROME P450 9B1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0286516|UniProtKB=Q9VHK8 Q9VHK8 aqz PTHR15405:SF0 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR AAQUETZALLI, ISOFORM A intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0032244|UniProtKB=Q9VKW3 Q9VKW3 RfC3 PTHR11669:SF9 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 5 ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA replication#GO:0006260 replication fork#GO:0005657;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 DROME|FlyBase=FBgn0053506|UniProtKB=A1Z9W2 A1Z9W2 CG10220 PTHR21824:SF4 TRANSMEMBRANE PROTEIN 177 TRANSMEMBRANE PROTEIN 177 membrane#GO:0016020;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0014127|UniProtKB=Q9VIP9 Q9VIP9 barr PTHR13108:SF9 CONDENSIN COMPLEX SUBUNIT 2 CONDENSIN COMPLEX SUBUNIT 2 chromatin binding#GO:0003682;binding#GO:0005488 cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome segregation#GO:0007059;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285 condensin complex#GO:0000796;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0035024|UniProtKB=Q9W149 Q9W149 Dmel\CG11414 PTHR22938:SF0 ZINC FINGER PROTEIN 598 E3 UBIQUITIN-PROTEIN LIGASE ZNF598 binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ribosome binding#GO:0043022;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;translation#GO:0006412;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular component organization#GO:0016043;protein modification by small protein conjugation#GO:0032446;rescue of stalled cytosolic ribosome#GO:0072344;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0041711|UniProtKB=Q9VFV1 Q9VFV1 yellow-e PTHR10009:SF19 PROTEIN YELLOW-RELATED RE55542P extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0259977|UniProtKB=A1Z6N2 A1Z6N2 Tdc1 PTHR11999:SF76 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE FI02861P lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;lyase#PC00144 DROME|FlyBase=FBgn0039733|UniProtKB=Q7K4R2 Q7K4R2 Vostok PTHR12243:SF63 MADF DOMAIN TRANSCRIPTION FACTOR SI:CH211-15D5.12 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0036144|UniProtKB=Q9VTG7 Q9VTG7 GlcAT-P PTHR10896:SF74 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE P UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 glycosyltransferase#PC00111 DROME|FlyBase=FBgn0039093|UniProtKB=Q9VCK7 Q9VCK7 Dmel\CG10183 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0031914|UniProtKB=Q9VM11 Q9VM11 Dmel\CG5973 PTHR10174:SF38 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED HL01515P phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0001215|UniProtKB=P07909 P07909 Hrb98DE PTHR48027:SF18 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0029629|UniProtKB=Q9W4X7 Q9W4X7 eIF3g1 PTHR10352:SF88 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 DROME|FlyBase=FBgn0033516|UniProtKB=A1Z884 A1Z884 Dmel\CG12898 PTHR20898:SF1 DAEDALUS ON 3-RELATED-RELATED MD-2-RELATED LIPID-RECOGNITION DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0032654|UniProtKB=Q9VJB9 Q9VJB9 Dmel\CG15147 PTHR33638:SF1 SELENOPROTEIN H SELENOPROTEIN H Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0030406|UniProtKB=Q8SX25 Q8SX25 Dmel\CG1463 PTHR13483:SF3 BOX C_D SNORNA PROTEIN 1-RELATED BOX C_D SNORNA PROTEIN 1 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0039315|UniProtKB=Q9VBT3 Q9VBT3 Dmel\CG13658 PTHR11012:SF12 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0085480|UniProtKB=A0A6M3QGH5 A0A6M3QGH5 CG33999 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 transferase#PC00220 DROME|FlyBase=FBgn0043536|UniProtKB=Q8MMF9 Q8MMF9 Obp57d PTHR11857:SF48 ODORANT BINDING PROTEIN-RELATED GENERAL ODORANT-BINDING PROTEIN 57C-RELATED sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0036493|UniProtKB=Q2PDY3 Q2PDY3 Dmel\CG7255 PTHR43243:SF105 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER C-TERMINAL DOMAIN-CONTAINING PROTEIN amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0259714|UniProtKB=A4IJ70 A4IJ70 DIP-epsilon PTHR12231:SF157 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN EPSILON-RELATED protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0016715|UniProtKB=Q94915 Q94915 Reg-2 PTHR46191:SF2 FAMILY NOT NAMED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0265974|UniProtKB=Q9V730 Q9V730 ttv PTHR11062:SF129 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-1 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0028693|UniProtKB=Q9V436 Q9V436 Rpn12 PTHR12387:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 proteasome complex#GO:0000502;nucleus#GO:0005634;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 DROME|FlyBase=FBgn0050082|UniProtKB=A0A0B4JCS5 A0A0B4JCS5 CR30082 PTHR24256:SF458 TRYPTASE-RELATED IP20273P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 DROME|FlyBase=FBgn0051954|UniProtKB=Q8IQ10 Q8IQ10 Dmel\CG31954 PTHR24276:SF97 POLYSERASE-RELATED GH13245P2-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0031975|UniProtKB=Q9VLU2 Q9VLU2 Tg PTHR11590:SF69 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 transferase#PC00220 DROME|FlyBase=FBgn0040297|UniProtKB=B7YZY2 B7YZY2 Nhe2 PTHR10110:SF98 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;import into cell#GO:0098657 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0261617|UniProtKB=M9MS40 M9MS40 nej PTHR13808:SF1 CBP/P300-RELATED HISTONE ACETYLTRANSFERASE histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transcription regulator activity#GO:0140110;acetyltransferase activity#GO:0016407;binding#GO:0005488;protein N-acetyltransferase activity#GO:0034212;transcription coactivator activity#GO:0003713;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;DNA binding#GO:0003677;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;nucleic acid binding#GO:0003676;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;chromatin DNA binding#GO:0031490;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 transferase complex#GO:1990234;transcription regulator complex#GO:0005667;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 Wnt signaling pathway#P00057>CBP#P01448;BMP/activin signaling pathway-drosophila#P06211>NEJ#P06246;DPP-SCW signaling pathway#P06212>NEJ#P06260;p53 pathway#P00059>CBP#P04623;Huntington disease#P00029>CBP#P00777;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;DPP signaling pathway#P06213>NEJ#P06284;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;SCW signaling pathway#P06216>NEJ#P06328;GBB signaling pathway#P06214>NEJ#P06295 DROME|FlyBase=FBgn0015770|UniProtKB=Q9VIA4 Q9VIA4 MstProx PTHR24365:SF555 TOLL-LIKE RECEPTOR MSTPROX-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0061197|UniProtKB=A1Z8W1 A1Z8W1 salto PTHR14136:SF17 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 DROME|FlyBase=FBgn0004507|UniProtKB=Q9XTL9 Q9XTL9 Glyp PTHR11468:SF13 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;generation of precursor metabolites and energy#GO:0006091;glycogen catabolic process#GO:0005980;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0034883|UniProtKB=A0A0C4DHF9 A0A0C4DHF9 Eglp2 PTHR19139:SF270 AQUAPORIN TRANSPORTER ENTOMOGLYCEROPORIN 1-RELATED channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;fluid transport#GO:0042044 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical part of cell#GO:0045177 transporter#PC00227 DROME|FlyBase=FBgn0037754|UniProtKB=Q9VH66 Q9VH66 Dmel\CG8500 PTHR24070:SF69 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY FI18258P1 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 DROME|FlyBase=FBgn0011259|UniProtKB=Q24322 Q24322 Sema1a PTHR11036:SF127 SEMAPHORIN SEMAPHORIN-1A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;taxis#GO:0042330;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 DROME|FlyBase=FBgn0024234|UniProtKB=P27091 P27091 gbb PTHR11848:SF310 TGF-BETA FAMILY PROTEIN 60A-RELATED cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 DPP-SCW signaling pathway#P06212>SCW full length#P06275;SCW signaling pathway#P06216>SCW#P06326;DPP-SCW signaling pathway#P06212>SCW#P06259;TGF-beta signaling pathway#P00052>TGFbeta#P01286;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;SCW signaling pathway#P06216>SCW full length#P06322;GBB signaling pathway#P06214>GBB#P06294;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256 DROME|FlyBase=FBgn0032940|UniProtKB=Q9VID4 Q9VID4 Mondo PTHR15741:SF37 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR LD38259P transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0037611|UniProtKB=Q9VHN3 Q9VHN3 CG11755 PTHR31849:SF1 CYSTEINE-RICH PDF MOTIF DOMAIN-CONTAINING PROTEIN 1 CYSTEINE-RICH DPF MOTIF DOMAIN-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0039118|UniProtKB=Q9VCH7 Q9VCH7 Dmel\CG10208 PTHR31527:SF0 RE64534P RE64534P DROME|FlyBase=FBgn0030968|UniProtKB=Q9VWP2 Q9VWP2 Dmel\CG7322 PTHR44252:SF3 D-ERYTHRULOSE REDUCTASE D-ERYTHRULOSE REDUCTASE-RELATED oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0283657|UniProtKB=B7Z126 B7Z126 Tlk PTHR22974:SF23 MIXED LINEAGE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0265265|UniProtKB=Q8IRP6 Q8IRP6 Dmel\CG32727 PTHR12763:SF28 FAMILY NOT NAMED GEO10507P1-RELATED DROME|FlyBase=FBgn0028962|UniProtKB=Q9VRJ1 Q9VRJ1 AlaRS-m PTHR11777:SF39 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;deacylase activity#GO:0160215;catalytic activity#GO:0003824 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 aminoacyl-tRNA synthetase#PC00047 DROME|FlyBase=FBgn0266417|UniProtKB=Q9VV43 Q9VV43 ringer PTHR12932:SF9 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;microtubule bundle formation#GO:0001578;positive regulation of cellular component organization#GO:0051130;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 DROME|FlyBase=FBgn0029809|UniProtKB=Q9W473 Q9W473 Dmel\CG15767 PTHR11071:SF594 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 DROME|FlyBase=FBgn0037087|UniProtKB=Q9VP29 Q9VP29 Dmel\CG7519 PTHR13410:SF9 PROTEIN PBDC1 PROTEIN PBDC1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 DROME|FlyBase=FBgn0034248|UniProtKB=Q4QPR8 Q4QPR8 Dmel\CG14483 PTHR33968:SF1 PROTEIN PET100 HOMOLOG, MITOCHONDRIAL PROTEIN PET100 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;chaperone-mediated protein complex assembly#GO:0051131;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0036183|UniProtKB=Q9VTL0 Q9VTL0 Ar7 PTHR11732:SF506 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE 1B-RELATED alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0063499|UniProtKB=Q4V6J1 Q4V6J1 GstE10 PTHR43969:SF4 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED FI01423P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0039355|UniProtKB=Q9VBN9 Q9VBN9 Dmel\CG4730 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0030029|UniProtKB=Q9W3G8 Q9W3G8 Dmel\CG15343 PTHR10851:SF4 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXAL 5'-PHOSPHATE SYNTHASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175 DROME|FlyBase=FBgn0032663|UniProtKB=Q9VJA6 Q9VJA6 Dmel\CG15153 PTHR33236:SF12 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0286898|UniProtKB=Q9VMA7 Q9VMA7 Tango1 PTHR23158:SF33 MELANOMA INHIBITORY ACTIVITY-RELATED TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0001189|UniProtKB=Q9W568 Q9W568 hfw PTHR46473:SF31 GH08155P PROTEIN HALFWAY DROME|FlyBase=FBgn0032053|UniProtKB=Q9VLJ9 Q9VLJ9 mRpL51 PTHR13409:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L51 LARGE RIBOSOMAL SUBUNIT PROTEIN ML51 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0061359|UniProtKB=Q7K2V9 Q7K2V9 Mvk PTHR43290:SF4 MEVALONATE KINASE MEVALONATE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;acyl-CoA metabolic process#GO:0006637;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;acetyl-CoA metabolic process#GO:0006084;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;sulfur compound metabolic process#GO:0006790;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;cholesterol biosynthetic process#GO:0006695;isoprenoid biosynthetic process#GO:0008299;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 carbohydrate kinase#PC00065 Cholesterol biosynthesis#P00014>Mevalonate kinase#P00492 DROME|FlyBase=FBgn0020249|UniProtKB=Q8INQ9 Q8INQ9 stck PTHR24210:SF0 LIM DOMAIN-CONTAINING PROTEIN LIM DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell junction organization#GO:0034330;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;positive regulation of signaling#GO:0023056;cell adhesion#GO:0007155;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 DROME|FlyBase=FBgn0036920|UniProtKB=Q9VW58 Q9VW58 Mtx2 PTHR12289:SF38 METAXIN RELATED METAXIN-2 protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;cellular component assembly#GO:0022607;membrane organization#GO:0061024;mitochondrion organization#GO:0007005 organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane translocase complex#GO:0005742;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 transporter#PC00227 DROME|FlyBase=FBgn0037017|UniProtKB=Q9VPC3 Q9VPC3 DSCR3 PTHR12233:SF2 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26C intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0031410|UniProtKB=Q9VQA5 Q9VQA5 Dmel\CG17237 PTHR23048:SF0 MYOSIN LIGHT CHAIN 1, 3 FI08416P-RELATED intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0053310|UniProtKB=Q7KT77 Q7KT77 Dmel\CG33310 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 monoatomic ion transport#GO:0006811;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0003687|UniProtKB=P20227 P20227 Tbp PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;Huntington disease#P00029>TBP#P00779 DROME|FlyBase=FBgn0283680|UniProtKB=Q7KV26 Q7KV26 IP3K2 PTHR12400:SF26 INOSITOL POLYPHOSPHATE KINASE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase#PC00137 DROME|FlyBase=FBgn0086447|UniProtKB=Q9VIZ0 Q9VIZ0 Polr1D PTHR13946:SF28 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 DROME|FlyBase=FBgn0030269|UniProtKB=M9PEA2 M9PEA2 CDK2AP1 PTHR22607:SF3 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CDK2-ASSOCIATED PROTEIN 1, ISOFORM B intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase modulator#PC00140;kinase inhibitor#PC00139 DROME|FlyBase=FBgn0004372|UniProtKB=Q9VZW3 Q9VZW3 aly PTHR21689:SF2 LIN-9 PROTEIN LIN-9 HOMOLOG DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0026371|UniProtKB=O97143 O97143 SAK PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;spindle#GO:0005819;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0032485|UniProtKB=Q9VK21 Q9VK21 Ipp PTHR24412:SF35 KELCH PROTEIN ACTIN-BINDING PROTEIN IPP enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036519|UniProtKB=Q9VUR7 Q9VUR7 PhLP1 PTHR46052:SF1 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN-LIKE PROTEIN 1 DROME|FlyBase=FBgn0010292|UniProtKB=P51406 P51406 bys PTHR12821:SF0 BYSTIN BYSTIN nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0002440|UniProtKB=P52302 P52302 l(3)mbn PTHR10380:SF119 CUTICLE PROTEIN PROTEIN LETHAL(3)MALIGNANT BLOOD NEOPLASM 1 extracellular matrix structural protein#PC00103 DROME|FlyBase=FBgn0033899|UniProtKB=A1Z9L5 A1Z9L5 Dmel\CG13016 PTHR12995:SF4 FI21814P1 FI21814P1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0283437|UniProtKB=Q7K2W6 Q7K2W6 PPO1 PTHR11511:SF24 LARVAL STORAGE PROTEIN/PHENOLOXIDASE TYROSINASE DROME|FlyBase=FBgn0024189|UniProtKB=Q0E9F2 Q0E9F2 sns PTHR11640:SF136 NEPHRIN NEPHRIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0019957|UniProtKB=P91929 P91929 ND-42 PTHR10513:SF15 DEOXYNUCLEOSIDE KINASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL deoxynucleoside kinase activity#GO:0019136;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 DROME|FlyBase=FBgn0038768|UniProtKB=Q9VDQ3 Q9VDQ3 idc PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0030336|UniProtKB=Q8MRI4 Q8MRI4 Dph6 PTHR12196:SF2 DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN DIPHTHINE--AMMONIA LIGASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 DROME|FlyBase=FBgn0040377|UniProtKB=Q9NEF6 Q9NEF6 Vha36-3 PTHR11671:SF5 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657 regulation of intracellular pH#GO:0051453;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of pH#GO:0006885;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;vacuolar acidification#GO:0007035;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;homeostatic process#GO:0042592 proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ATP synthase#PC00002 DROME|FlyBase=FBgn0250732|UniProtKB=Q6NP69 Q6NP69 gfzf PTHR43969:SF7 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GST-CONTAINING FLYWCH ZINC-FINGER PROTEIN transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 DROME|FlyBase=FBgn0039489|UniProtKB=Q9VB73 Q9VB73 Dmel\CG5880 PTHR12246:SF26 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0051092|UniProtKB=Q7YU01 Q7YU01 LpR2 PTHR24270:SF68 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LD11117P-RELATED localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transfer/carrier protein#PC00219;apolipoprotein#PC00052 DROME|FlyBase=FBgn0085405|UniProtKB=Q9VD05 Q9VD05 CG13851 PTHR23110:SF113 BTB DOMAIN TRANSCRIPTION FACTOR FI07618P-RELATED regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0264750|UniProtKB=M9PBA3 M9PBA3 CG42325 PTHR21131:SF0 SERINE-TYPE ENDOPEPTIDASE INHIBITOR GEO10195P1-RELATED protease inhibitor#PC00191 DROME|FlyBase=FBgn0038819|UniProtKB=Q9VDJ8 Q9VDJ8 Cpr92F PTHR12236:SF92 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 92F extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0028410|UniProtKB=Q9VK37 Q9VK37 Pk34A PTHR24056:SF594 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 5 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;organelle localization#GO:0051640;cell death#GO:0008219;programmed cell death#GO:0012501;neurogenesis#GO:0022008;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;vesicle localization#GO:0051648;axon development#GO:0061564;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular localization#GO:0051641;neuron apoptotic process#GO:0051402;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;establishment of organelle localization#GO:0051656;cell differentiation#GO:0030154;cell projection organization#GO:0030030;apoptotic process#GO:0006915;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489;neuron projection development#GO:0031175 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Axon guidance mediated by semaphorins#P00007>Cdk5#P00336;Dopamine receptor mediated signaling pathway#P05912>CDK5#P05951;Nicotine pharmacodynamics pathway#P06587>CDK5#P06597;PDGF signaling pathway#P00047>GSK3#P01153;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902 DROME|FlyBase=FBgn0003204|UniProtKB=Q07152 Q07152 ras PTHR11911:SF111 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 DROME|FlyBase=FBgn0036589|UniProtKB=Q9VV11 Q9VV11 anon-WO0153538.46 PTHR35685:SF2 825-OAK-RELATED-RELATED 825-OAK-RELATED DROME|FlyBase=FBgn0023081|UniProtKB=Q9W1B0 Q9W1B0 gek PTHR22988:SF75 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE GENGHIS KHAN protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0085400|UniProtKB=A0A0C4DH96 A0A0C4DH96 side-V PTHR23278:SF2 SIDESTEP PROTEIN SIDESTEP V, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 DROME|FlyBase=FBgn0031360|UniProtKB=Q9VQ39 Q9VQ39 Dmel\CG31937 PTHR44269:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED IP05441P oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 dehydrogenase#PC00092 DROME|FlyBase=FBgn0050049|UniProtKB=A1Z8X5 A1Z8X5 CG30049-PA PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0015609|UniProtKB=O15943 O15943 CadN PTHR24025:SF23 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 DROME|FlyBase=FBgn0263116|UniProtKB=P28286 P28286 5-HT1B PTHR24247:SF241 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2A-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 DROME|FlyBase=FBgn0035911|UniProtKB=Q9VSL9 Q9VSL9 Ivd PTHR43884:SF47 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;dehydrogenase#PC00092 DROME|FlyBase=FBgn0030054|UniProtKB=Q9W3D1 Q9W3D1 Caf1-180 PTHR15272:SF0 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0040080|UniProtKB=Q9VB22 Q9VB22 pins PTHR45954:SF1 LD33695P LD33695P molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;protein binding#GO:0005515;binding#GO:0005488 establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;spindle localization#GO:0051653;localization#GO:0051179;organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944 DROME|FlyBase=FBgn0031575|UniProtKB=Q9VQV7 Q9VQV7 Cep97 PTHR45973:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTROSOMAL PROTEIN OF 97 KDA regulation of cell projection assembly#GO:0060491;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;negative regulation of cellular process#GO:0048523;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 DROME|FlyBase=FBgn0040298|UniProtKB=Q9NI63 Q9NI63 Myt1 PTHR11042:SF183 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 sexual reproduction#GO:0019953;cellular process#GO:0009987;meiotic cell cycle#GO:0051321;cell cycle#GO:0007049;reproductive process#GO:0022414 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0038481|UniProtKB=Q9VEM8 Q9VEM8 Dmel\CG17475 PTHR24260:SF138 AT07769P-RELATED IP10340P-RELATED DROME|FlyBase=FBgn0085398|UniProtKB=Q9W2B5 Q9W2B5 ppk9 PTHR11690:SF240 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 25-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0035213|UniProtKB=Q8IRH5 Q8IRH5 indra PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0033987|UniProtKB=Q7JQG5 Q7JQG5 ckn PTHR24155:SF11 OSTEOCLAST-STIMULATING FACTOR 1 CASKIN, ISOFORM B protein phosphatase binding#GO:0019903;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;phosphatase binding#GO:0019902;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899 neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;focal adhesion#GO:0005925;cell projection#GO:0042995;cell-substrate junction#GO:0030055;neuron projection#GO:0043005;cell junction#GO:0030054;anchoring junction#GO:0070161;axon#GO:0030424 DROME|FlyBase=FBgn0033813|UniProtKB=A1Z9A5 A1Z9A5 fsd PTHR20988:SF2 TRANSMEMBRANE PROTEIN 183A-RELATED TRANSMEMBRANE PROTEIN 183A-RELATED ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 DROME|FlyBase=FBgn0034792|UniProtKB=F3YDF1 F3YDF1 YME1L PTHR43655:SF38 ATP-DEPENDENT PROTEASE ATP-DEPENDENT ZINC METALLOPROTEASE YME1L catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0032132|UniProtKB=Q9VLA3 Q9VLA3 Dmel\CG4382 PTHR11559:SF370 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE-RELATED esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 DROME|FlyBase=FBgn0038400|UniProtKB=Q9VEY5 Q9VEY5 Mic26-27 PTHR14564:SF4 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT cellular component organization or biogenesis#GO:0071840;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;membrane organization#GO:0061024 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0043362|UniProtKB=Q9VML2 Q9VML2 bchs PTHR46108:SF4 BLUE CHEESE BLUE CHEESE DROME|FlyBase=FBgn0033668|UniProtKB=A1Z8R1 A1Z8R1 exp PTHR22742:SF2 EXPANSION, ISOFORM A-RELATED EXPANSION, ISOFORM A-RELATED DROME|FlyBase=FBgn0053757|UniProtKB=A1Z7U8 A1Z7U8 Dmel\CG33757 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0034877|UniProtKB=Q9W1N3 Q9W1N3 levy PTHR11504:SF17 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277 oxidase#PC00175 DROME|FlyBase=FBgn0004878|UniProtKB=Q7M3M8 Q7M3M8 cas PTHR12451:SF0 TRANSCRIPTION FACTOR CASTOR PROTEIN MING -RELATED ZINC FINGER PROTEIN CASTOR HOMOLOG 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of neuron differentiation#GO:0045664;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cell differentiation#GO:0045595;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0035543|UniProtKB=Q9VZC5 Q9VZC5 Dmel\CG15020 PTHR46560:SF3 CYPHER, ISOFORM B ZP DOMAIN-CONTAINING PROTEIN developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell morphogenesis#GO:0000902 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0035035|UniProtKB=Q9W138 Q9W138 CG3570 PTHR21008:SF2 S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE-RELATED molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 DROME|FlyBase=FBgn0005617|UniProtKB=P50535 P50535 msl-1 PTHR21656:SF2 MALE-SPECIFIC LETHAL-1 PROTEIN MALE-SPECIFIC LETHAL 1 HOMOLOG binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;chromatin binding#GO:0003682 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0002791|UniProtKB=Q9W1E5 Q9W1E5 mr PTHR45957:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 cellular process#GO:0009987;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of chromosome segregation#GO:0051983;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;protein K11-linked ubiquitination#GO:0070979;cell cycle#GO:0007049;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;mitotic cell cycle phase transition#GO:0044772;protein modification by small protein conjugation or removal#GO:0070647;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 Cell cycle#P00013>APC#P00481 DROME|FlyBase=FBgn0036135|UniProtKB=Q9VTF8 Q9VTF8 mRpL2 PTHR13691:SF73 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 DROME|FlyBase=FBgn0031304|UniProtKB=Q9VPW9 Q9VPW9 TBC1D23 PTHR13297:SF5 TBC1 DOMAIN FAMILY MEMBER 23-RELATED TBC1 DOMAIN FAMILY MEMBER 23 retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802 DROME|FlyBase=FBgn0020621|UniProtKB=A1Z7T0 A1Z7T0 Pkn PTHR24356:SF210 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 DROME|FlyBase=FBgn0030598|UniProtKB=Q9VY00 Q9VY00 Dm GMCalpha1 PTHR11552:SF229 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE ECDYSONE OXIDASE-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036271|UniProtKB=Q9VTV9 Q9VTV9 Pbgs PTHR11458:SF0 DELTA-AMINOLEVULINIC ACID DEHYDRATASE DELTA-AMINOLEVULINIC ACID DEHYDRATASE hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound biosynthetic process#GO:0006779 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydratase#PC00091 Heme biosynthesis#P02746>porphobilinogen synthase#P02979 DROME|FlyBase=FBgn0039017|UniProtKB=Q9VCU8 Q9VCU8 Dmel\CG6985 PTHR45629:SF16 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54B DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 reproductive process#GO:0022414;homologous recombination#GO:0035825;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;response to stimulus#GO:0050896;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 damaged DNA-binding protein#PC00086 DROME|FlyBase=FBgn0003410|UniProtKB=P21461 P21461 sina PTHR45877:SF2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SINA-RELATED ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433 DROME|FlyBase=FBgn0039925|UniProtKB=Q9V4A1 Q9V4A1 Kif3C PTHR24115:SF1046 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF17 binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111 microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 DROME|FlyBase=FBgn0034259|UniProtKB=Q7JXC4 Q7JXC4 P32 PTHR10826:SF1 COMPLEMENT COMPONENT 1 COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL protein-RNA adaptor activity#GO:0140517;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mitochondrial RNA metabolic process#GO:0000959;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 complement component#PC00078;defense/immunity protein#PC00090 DROME|FlyBase=FBgn0000283|UniProtKB=Q24478 Q24478 Cp190 PTHR24394:SF64 ZINC FINGER PROTEIN CENTROSOME-ASSOCIATED ZINC FINGER PROTEIN CP190 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0038376|UniProtKB=Q9VF20 Q9VF20 Hmt-1 PTHR24221:SF664 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0267376|UniProtKB=Q8INK9 Q8INK9 SelR PTHR10173:SF52 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;reductase#PC00198;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039600|UniProtKB=Q7KRW8 Q7KRW8 Prp39 PTHR17204:SF5 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED PRE-MRNA-PROCESSING FACTOR 39 binding#GO:0005488;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0052064|UniProtKB=Q95R35 Q95R35 S-Lap4 PTHR11963:SF16 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0020018|UniProtKB=Q9VC52 Q9VC52 Ppox PTHR42923:SF3 PROTOPORPHYRINOGEN OXIDASE PROTOPORPHYRINOGEN OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Protoporphyrinogen oxidase#P02976 DROME|FlyBase=FBgn0004779|UniProtKB=O97062 O97062 Ccp84Ae PTHR12236:SF94 STRUCTURAL CONSTITUENT OF CUTICLE CCP84AA-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0085362|UniProtKB=A8JUV4 A8JUV4 Vml PTHR47641:SF14 PERIAXIN-LIKE GOLGI-ASSOCIATED OLFACTORY SIGNALING REGULATOR DROME|FlyBase=FBgn0036814|UniProtKB=Q8IQT4 Q8IQT4 Nirvana PTHR24117:SF9 AGAP007537-PB BCL-6 COREPRESSOR PCGF1 BINDING DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DROME|FlyBase=FBgn0051693|UniProtKB=Q7KRS1 Q7KRS1 Dmel\CG31693 PTHR43568:SF1 P PROTEIN CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0050177|UniProtKB=Q8MLQ8 Q8MLQ8 Dmel\CG30177 PTHR12300:SF197 HVA22-LIKE PROTEINS LP05237P-RELATED cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0038887|UniProtKB=Q4V551 Q4V551 Dmel\CG7907 PTHR12412:SF2 CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0031980|UniProtKB=Q9VLT7 Q9VLT7 RpL36A PTHR10369:SF3 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 DROME|FlyBase=FBgn0087008|UniProtKB=Q9VWF2 Q9VWF2 e(y)3 PTHR23202:SF130 WASP INTERACTING PROTEIN-RELATED MULTI SEX COMBS, ISOFORM A-RELATED nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0025582|UniProtKB=O77410 O77410 eIF3e PTHR10317:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;eukaryotic translation initiation factor 3 complex#GO:0005852 translation factor#PC00223;translation initiation factor#PC00224 DROME|FlyBase=FBgn0033243|UniProtKB=Q7K035 Q7K035 Dmel\CG14763 PTHR21255:SF69 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN AT23443P binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0033526|UniProtKB=A1Z898 A1Z898 Caf1-105 PTHR15271:SF4 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0041707|UniProtKB=Q59E04 Q59E04 7B2 PTHR12738:SF0 NEUROENDOCRINE PROTEIN 7B2 NEUROENDOCRINE PROTEIN 7B2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789 chaperone#PC00072 DROME|FlyBase=FBgn0086365|UniProtKB=Q95R48 Q95R48 Orct2 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0026755|UniProtKB=Q9VMG1 Q9VMG1 Ugt37B1 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 DROME|FlyBase=FBgn0039478|UniProtKB=Q8IMQ2 Q8IMQ2 Nep5 PTHR11733:SF246 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN 5, ISOFORM D catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0031171|UniProtKB=Q9VRG5 Q9VRG5 Dmel\CG1801 PTHR19229:SF282 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0259933|UniProtKB=E1JIA5 E1JIA5 Dpm2 PTHR15039:SF11 DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mannosyltransferase complex#GO:0031501;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 DROME|FlyBase=FBgn0035533|UniProtKB=A8JNK4 A8JNK4 Cip4 PTHR15735:SF12 FCH AND DOUBLE SH3 DOMAINS PROTEIN CDC42-INTERACTING PROTEIN 4, ISOFORM B regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0029911|UniProtKB=Q9W3V3 Q9W3V3 detr PTHR46661:SF4 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0030089|UniProtKB=Q7KVR8 Q7KVR8 AP-1gamma PTHR22780:SF5 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 Golgi to endosome transport#GO:0006895;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892 vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0025635|UniProtKB=O77260 O77260 Hinfp PTHR24391:SF30 HISTONE H4 TRANSCRIPTION FACTOR-RELATED EG:115C2.6 PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0037057|UniProtKB=Q9VP68 Q9VP68 Dmel\CG10512 PTHR11091:SF0 OXIDOREDUCTASE-RELATED MALATE DEHYDROGENASE metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Allantoin degradation#P02725>Ureidoglycolate dehydrogenase#P02820;TCA cycle#P00051>Malate Dehydrogenase#P01270;Pyruvate metabolism#P02772>Malate Dehydrogenase#P03138 DROME|FlyBase=FBgn0002673|UniProtKB=Q03019 Q03019 twe PTHR10828:SF17 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 CDC25-LIKE PROTEIN PHOSPHATASE TWINE-RELATED catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;regulation of reproductive process#GO:2000241;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of meiotic cell cycle#GO:0051445;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DROME|FlyBase=FBgn0029791|UniProtKB=Q9W493 Q9W493 AdamTS-B PTHR13723:SF200 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF B, ISOFORM B catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 DROME|FlyBase=FBgn0053971|UniProtKB=Q2MGM0 Q2MGM0 Ir62a PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0023000|UniProtKB=O97148 O97148 mth PTHR47154:SF2 G-PROTEIN COUPLED RECEPTOR MTH-RELATED G-PROTEIN COUPLED RECEPTOR MTH-RELATED molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0289868|UniProtKB=Q9VT90 Q9VT90 Or67c PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0038072|UniProtKB=Q9VG44 Q9VG44 Dmel\CG6225 PTHR43763:SF4 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 2 protease#PC00190 DROME|FlyBase=FBgn0010173|UniProtKB=Q24492 Q24492 RPA1 PTHR23273:SF4 REPLICATION FACTOR A 1, RFA1 REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT DNA binding#GO:0003677;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684 telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;nucleotide-excision repair#GO:0006289;organelle organization#GO:0006996;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;response to stimulus#GO:0050896;cellular component organization#GO:0016043;double-strand break repair via homologous recombination#GO:0000724;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;RNA-templated DNA biosynthetic process#GO:0006278;DNA repair#GO:0006281;DNA damage response#GO:0006974;reproductive process#GO:0022414;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;telomere organization#GO:0032200;recombinational repair#GO:0000725;sexual reproduction#GO:0019953 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;protein-DNA complex#GO:0032993;replication fork#GO:0005657;replisome#GO:0030894;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0259742|UniProtKB=Q9W135 Q9W135 CG13588 PTHR12876:SF35 N4BP1-RELATED LD08718P-RELATED nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 endoribonuclease#PC00094 DROME|FlyBase=FBgn0082598|UniProtKB=Q9VS59 Q9VS59 akirin PTHR13293:SF6 AKIRIN-RELATED AKIRIN-RELATED transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of response to biotic stimulus#GO:0002831;positive regulation of RNA metabolic process#GO:0051254;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of response to external stimulus#GO:0032103;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 DROME|FlyBase=FBgn0030096|UniProtKB=Q9W379 Q9W379 Zpr1 PTHR10876:SF7 ZINC FINGER PROTEIN ZPR1 ZINC FINGER PROTEIN ZPR1 binding#GO:0005488;protein binding#GO:0005515 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DROME|FlyBase=FBgn0005619|UniProtKB=Q05733 Q05733 Hdc PTHR11999:SF68 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE HISTIDINE DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;lyase activity#GO:0016829 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;amine metabolic process#GO:0009308;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 lyase#PC00144;decarboxylase#PC00089 CCKR signaling map#P06959>HDC#G07262;CCKR signaling map#P06959>HDC#G06969;Histamine synthesis#P04387>Histidine decarboxylase#P04493 DROME|FlyBase=FBgn0011761|UniProtKB=P47938 P47938 dhd PTHR10438:SF475 THIOREDOXIN THIOREDOXIN catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 DROME|FlyBase=FBgn0046887|UniProtKB=Q9VB26 Q9VB26 Gr98b PTHR21143:SF131 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND ODORANT RECEPTOR 63A-RELATED cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;neuron projection#GO:0043005;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039877|UniProtKB=Q9V9T5 Q9V9T5 Mccc1 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;ligase#PC00142 DROME|FlyBase=FBgn0033375|UniProtKB=Q7JWW5 Q7JWW5 Ctu1 PTHR11807:SF12 ATPASES OF THE PP SUPERFAMILY-RELATED CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1 RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble position uridine thiolation#GO:0002143;tRNA thio-modification#GO:0034227;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;sulfurtransferase complex#GO:1990228;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0036248|UniProtKB=Q9VTT3 Q9VTT3 ssp PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0036450|UniProtKB=Q9VUH8 Q9VUH8 Tdrd3 PTHR13681:SF24 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED TUDOR DOMAIN-CONTAINING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;nucleic acid binding#GO:0003676;histone reader activity#GO:0140566;RNA binding#GO:0003723;chromatin-protein adaptor activity#GO:0140463 siRNA-mediated heterochromatin formation#GO:0141194;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;cellular component assembly#GO:0022607;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0260484|UniProtKB=C4NYP8 C4NYP8 HIP PTHR45883:SF2 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 DROME|FlyBase=FBgn0039812|UniProtKB=Q9VA23 Q9VA23 Dmel\CG15548 PTHR41967:SF6 FI19406P1-RELATED FI19406P1-RELATED DROME|FlyBase=FBgn0032281|UniProtKB=Q9VKS2 Q9VKS2 Dmel\CG17107 PTHR22552:SF25 GEO11429P1 GEO11429P1-RELATED DROME|FlyBase=FBgn0030589|UniProtKB=Q9VY09 Q9VY09 Dmel\CG9519 PTHR11552:SF158 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE GH23626P-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0001134|UniProtKB=Q24352 Q24352 Grd PTHR18945:SF944 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR ALPHA-LIKE cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0031850|UniProtKB=Q9VM97 Q9VM97 Tsp PTHR10199:SF100 THROMBOSPONDIN THROMBOSPONDIN, ISOFORM A structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0011770|UniProtKB=P36951 P36951 Gip PTHR43489:SF6 ISOMERASE HYDROXYPYRUVATE ISOMERASE-RELATED intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 isomerase#PC00135;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0005648|UniProtKB=Q7KNF2 Q7KNF2 Pabp2 PTHR23236:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC INITIATION FACTOR 4B-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;poly(A) binding#GO:0008143;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 DROME|FlyBase=FBgn0052549|UniProtKB=Q9VWV5 Q9VWV5 Nt5b PTHR12103:SF15 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5' NUCLEOTIDASE B, ISOFORM G catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 DROME|FlyBase=FBgn0039623|UniProtKB=Q9VAR0 Q9VAR0 Dmel\CG1951 PTHR12984:SF6 SCY1-RELATED S/T PROTEIN KINASE-LIKE SCY1-LIKE PROTEIN 2 non-receptor serine/threonine protein kinase#PC00167 DROME|Gene_ORFName=Dmel_CG46521|UniProtKB=A0ACD4DAY5 A0ACD4DAY5 CG46521 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0026399|UniProtKB=A0A0B4KGT9 A0A0B4KGT9 Or85e PTHR21137:SF42 ODORANT RECEPTOR ODORANT RECEPTOR 83A transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0030483|UniProtKB=Q9VYD4 Q9VYD4 Dmel\CG12725 PTHR10666:SF438 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN ES31 FUSION PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;nucleus#GO:0005634;ribosome#GO:0005840 DROME|FlyBase=FBgn0031768|UniProtKB=Q9VMI6 Q9VMI6 IPIP PTHR22902:SF53 SESQUIPEDALIAN SESQUIPEDALIAN intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endosome organization#GO:0007032;vesicle organization#GO:0016050;endosomal transport#GO:0016197;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;cytosolic transport#GO:0016482 endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle subcompartment#GO:0031984;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0037290|UniProtKB=Q9VN73 Q9VN73 Jhbp1 PTHR11008:SF41 PROTEIN TAKEOUT-LIKE PROTEIN JUVENILE HORMONE BINDING PROTEIN 1 circadian rhythm#GO:0007623;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0003660|UniProtKB=P18489 P18489 Syb PTHR45701:SF3 SYNAPTOBREVIN FAMILY MEMBER SYNAPTOBREVIN molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484 transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle fusion#GO:0006906 intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150 Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986 DROME|FlyBase=FBgn0037685|UniProtKB=Q9VHE6 Q9VHE6 Or85f PTHR21137:SF44 ODORANT RECEPTOR ODORANT RECEPTOR 13A-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0053688|UniProtKB=Q4ABJ2 Q4ABJ2 Dmel\CG33688 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0035294|UniProtKB=Q9W062 Q9W062 Mfap1 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0085201|UniProtKB=Q6IHY5 Q6IHY5 COX7AL2 PTHR10510:SF13 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A-LIKE-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;membrane#GO:0016020;respiratory chain complex#GO:0098803;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175 DROME|FlyBase=FBgn0037351|UniProtKB=Q9VNE9 Q9VNE9 RpL13A PTHR11545:SF3 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of translation#GO:0017148;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0037801|UniProtKB=Q9VH09 Q9VH09 Gldc PTHR11773:SF1 GLYCINE DEHYDROGENASE, DECARBOXYLATING GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0051030|UniProtKB=Q0KHY8 Q0KHY8 VhaAC45RP PTHR12471:SF4 VACUOLAR ATP SYNTHASE SUBUNIT S1 VHAAC45-RELATED PROTEIN, ISOFORM B homeostatic process#GO:0042592;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane#GO:0016020;proton-transporting V-type ATPase complex#GO:0033176;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;ATPase complex#GO:1904949;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0037939|UniProtKB=Q9VGJ3 Q9VGJ3 Dmel\CG14718 PTHR23238:SF26 RNA BINDING PROTEIN GH13594P-RELATED RNA binding#GO:0003723;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0053635|UniProtKB=Q6II06 Q6II06 Dmel\CG33635 PTHR23137:SF36 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2C DROME|FlyBase=FBgn0000256|UniProtKB=Q24120 Q24120 capu PTHR13037:SF24 FORMIN POLYCOMB PROTEIN PCL-RELATED DROME|FlyBase=FBgn0053087|UniProtKB=A0A0B4KFD1 A0A0B4KFD1 LRP1 PTHR22722:SF17 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR ISOFORM X1 DROME|FlyBase=FBgn0004898|UniProtKB=P32029 P32029 fd96Cb PTHR11829:SF377 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD4-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0039613|UniProtKB=Q9VAS0 Q9VAS0 Nepl20 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0033130|UniProtKB=Q7JZW3 Q7JZW3 Tsp42Ei PTHR19282:SF519 TETRASPANIN TETRASPANIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0263240|UniProtKB=Q7JUZ9 Q7JUZ9 Coop PTHR12243:SF67 MADF DOMAIN TRANSCRIPTION FACTOR COREPRESSOR OF PANGOLIN, ISOFORM A-RELATED regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0025111|UniProtKB=O62526 O62526 Ant2 PTHR45635:SF56 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE purine nucleotide transmembrane transporter activity#GO:0015216;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505 transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;regulation of membrane permeability#GO:0090559;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;organelle membrane#GO:0031090 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0002641|UniProtKB=Q9VRA2 Q9VRA2 mal PTHR14237:SF96 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MOLYBDENUM COFACTOR SULFURASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 DROME|FlyBase=FBgn0040206|UniProtKB=Q9V393 Q9V393 krz PTHR11792:SF17 ARRESTIN KURTZ ARRESTIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 negative regulation of cellular process#GO:0048523;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;receptor internalization#GO:0031623;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;nervous system process#GO:0050877;sensory perception#GO:0007600;localization#GO:0051179;negative regulation of cell communication#GO:0010648;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Wnt signaling pathway#P00057>beta-arrestin#P01456;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723 DROME|FlyBase=FBgn0032036|UniProtKB=Q9VLM3 Q9VLM3 Dmel\CG13384 PTHR22950:SF349 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0034194|UniProtKB=A1ZAQ4 A1ZAQ4 Dmel\CG15611 PTHR22826:SF209 RHO GUANINE EXCHANGE FACTOR-RELATED DH DOMAIN-CONTAINING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0028473|UniProtKB=Q9V411 Q9V411 Non1 PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 GTP-BINDING PROTEIN 4 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0032416|UniProtKB=Q9VKA5 Q9VKA5 Gr33a PTHR21143:SF132 INVERTEBRATE GUSTATORY RECEPTOR GUSTATORY AND PHEROMONE RECEPTOR 33A-RELATED cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0029906|UniProtKB=Q9W3V8 Q9W3V8 xit PTHR12413:SF2 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0028895|UniProtKB=Q9VJL7 Q9VJL7 DS02740.8 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0040011|UniProtKB=Q9W5R5 Q9W5R5 Slmap PTHR15715:SF52 CENTROSOMAL PROTEIN OF 170 KDA SARCOLEMMAL MEMBRANE-ASSOCIATED PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646 protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0266670|UniProtKB=Q9VQQ9 Q9VQQ9 Sec5 PTHR13043:SF1 EXOCYST COMPLEX COMPONENT SEC5 EXOCYST COMPLEX COMPONENT 2 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;secretion by cell#GO:0032940;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179 vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;exocyst#GO:0000145 Ras Pathway#P04393>Sec5#P04545 DROME|FlyBase=FBgn0038484|UniProtKB=Q9VEM6 Q9VEM6 Dmel\CG5246 PTHR24260:SF138 AT07769P-RELATED IP10340P-RELATED DROME|FlyBase=FBgn0051760|UniProtKB=Q9VKA4 Q9VKA4 CG31760 PTHR32546:SF16 G-PROTEIN COUPLED RECEPTOR 158-RELATED G-PROTEIN COUPLED RECEPTOR CG31760-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0039359|UniProtKB=Q9VBN5 Q9VBN5 RpL27 PTHR10497:SF0 60S RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN EL27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202 DROME|FlyBase=FBgn0034137|UniProtKB=A1ZAH6 A1ZAH6 Dmel\CG4945 PTHR24359:SF1 SERINE/THREONINE-PROTEIN KINASE SBK1 INACTIVE PROTEIN KINASE DDB_G0270444-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0034664|UniProtKB=Q9W2C4 Q9W2C4 Dmel\CG4377 PTHR21721:SF26 GH09876P-RELATED DUF753 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0042178|UniProtKB=Q9I7R5 Q9I7R5 Apl PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 DROME|FlyBase=FBgn0053923|UniProtKB=Q4ABI4 Q4ABI4 Dmel\CG33923 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0030949|UniProtKB=Q9VWR2 Q9VWR2 Cyp308a1 PTHR24292:SF104 CYTOCHROME P450 CYTOCHROME P450 308A1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0034833|UniProtKB=Q9W1T5 Q9W1T5 Dmel\CG13539 PTHR21644:SF0 AT02555P-RELATED AT02555P-RELATED DROME|FlyBase=FBgn0050359|UniProtKB=Q5U124 Q5U124 Mal-A5 PTHR10357:SF235 ALPHA-GLUCOSIDASE FAMILY MEMBER MALTASE A3-RELATED oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;cellular process#GO:0009987;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;amylase#PC00048 DROME|FlyBase=FBgn0030574|UniProtKB=Q8IR48 Q8IR48 sbm PTHR11785:SF512 AMINO ACID TRANSPORTER B(0,+)-TYPE AMINO ACID TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 DROME|FlyBase=FBgn0037943|UniProtKB=Q8T088 Q8T088 CG14722 PTHR44019:SF20 WD REPEAT-CONTAINING PROTEIN 55 WD REPEAT-CONTAINING PROTEIN 55 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0035388|UniProtKB=E1JIB4 E1JIB4 anon-EST:Posey170 PTHR21678:SF0 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 C3H1-TYPE DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0001247|UniProtKB=P22817 P22817 Ide PTHR43690:SF37 NARDILYSIN INSULIN-DEGRADING ENZYME hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteolysis#GO:0006508;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 DROME|FlyBase=FBgn0260991|UniProtKB=Q7JRJ9 Q7JRJ9 Incenp PTHR13142:SF1 INNER CENTROMERE PROTEIN INNER CENTROMERE PROTEIN chromosome#GO:0005694;midbody#GO:0030496;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0035437|UniProtKB=Q8IRD5 Q8IRD5 Strip PTHR13239:SF4 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 AT25231P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of signal transduction#GO:0009968;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DROME|FlyBase=FBgn0029521|UniProtKB=Q9W5G6 Q9W5G6 Or1a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0266566|UniProtKB=Q9VF13 Q9VF13 CG34275 PTHR34343:SF1 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 developmental process#GO:0032502;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;anatomical structure formation involved in morphogenesis#GO:0048646;microtubule organizing center organization#GO:0031023;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;tube development#GO:0035295;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;cell migration#GO:0016477;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;cell motility#GO:0048870;cell differentiation#GO:0030154 microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0039576|UniProtKB=Q9VAW7 Q9VAW7 UQCR-14L PTHR12022:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0034113|UniProtKB=A1ZAE2 A1ZAE2 Dmel\CG8060 PTHR22872:SF11 BTK-BINDING PROTEIN-RELATED BTB DOMAIN-CONTAINING PROTEIN calcium ion transmembrane transport#GO:0070588;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811 DROME|FlyBase=FBgn0025615|UniProtKB=O77277 O77277 Torsin PTHR10760:SF18 TORSIN LD13476P-RELATED response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;response to stress#GO:0006950;response to misfolded protein#GO:0051788;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to misfolded protein#GO:0071218 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 DROME|FlyBase=FBgn0030050|UniProtKB=Q9W3D8 Q9W3D8 Dmel\CG12111 PTHR22802:SF456 C-TYPE LECTIN SUPERFAMILY MEMBER AT17652P-RELATED carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0283468|UniProtKB=A0A0B4KHK1 A0A0B4KHK1 slmb PTHR44156:SF29 SUPERNUMERARY LIMBS, ISOFORM B-RELATED SUPERNUMERARY LIMBS, ISOFORM B ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cell cycle#GO:0051726;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;regulation of protein catabolic process#GO:0042176;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 Toll pathway-drosophila#P06217>SLMB#P06348 DROME|FlyBase=FBgn0037989|UniProtKB=Q9VGD4 Q9VGD4 ATP8B PTHR24092:SF190 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869 cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 DROME|FlyBase=FBgn0030429|UniProtKB=Q9VYI8 Q9VYI8 Dmel\CG4661 PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0032650|UniProtKB=Q9VJC2 Q9VJC2 Dmel\CG7094 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular process#GO:0009987;signal transduction#GO:0007165;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 DROME|FlyBase=FBgn0034186|UniProtKB=Q7JVW5 Q7JVW5 Gtf3c3 PTHR23082:SF0 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription factor TFIIIC complex#GO:0000127;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 DROME|FlyBase=FBgn0036941|UniProtKB=Q9VW82 Q9VW82 Khkl1 PTHR43085:SF55 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate metabolic process#GO:0005975;regulation of carbohydrate biosynthetic process#GO:0043255;small molecule metabolic process#GO:0044281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of glycogen biosynthetic process#GO:0005979;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;regulation of carbohydrate metabolic process#GO:0006109;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;transferase#PC00220 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 DROME|FlyBase=FBgn0033225|UniProtKB=Q7JVG6 Q7JVG6 TTLL12 PTHR46088:SF1 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0087040|UniProtKB=P06606 P06606 alphaTub67C PTHR11588:SF513 TUBULIN TUBULIN ALPHA-4 CHAIN carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 DROME|FlyBase=FBgn0035283|UniProtKB=Q8SZU6 Q8SZU6 Dmel\CG12024 PTHR13467:SF3 CUE DOMAIN CONTAINING PROTEIN 1 CUE DOMAIN-CONTAINING PROTEIN 1 DROME|FlyBase=FBgn0053509|UniProtKB=Q59DY1 Q59DY1 CG14398 PTHR11012:SF59 PROTEIN KINASE-LIKE DOMAIN-CONTAINING CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0013749|UniProtKB=P40945 P40945 Arf4 PTHR11711:SF481 ADP RIBOSYLATION FACTOR-RELATED ADP RIBOSYLATION FACTOR 4 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 DROME|FlyBase=FBgn0052282|UniProtKB=Q8IRD6 Q8IRD6 Drsl4 PTHR33147:SF98 DEFENSIN-LIKE PROTEIN 1 DRO1 PROTEIN-RELATED response to stimulus#GO:0050896;defense response#GO:0006952;response to stress#GO:0006950 antimicrobial response protein#PC00051 DROME|FlyBase=FBgn0001970|UniProtKB=Q8MVS5 Q8MVS5 Pgant35A PTHR11675:SF63 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;biosynthetic process#GO:0009058;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0033260|UniProtKB=Q5BI50 Q5BI50 Cul4 PTHR11932:SF177 CULLIN CULLIN-4A structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;DNA damage response#GO:0006974;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 DROME|FlyBase=FBgn0038047|UniProtKB=Q9VG72 Q9VG72 Dmel\CG5245 PTHR24377:SF995 IP01015P-RELATED LD25464P-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0037660|UniProtKB=Q9VHH8 Q9VHH8 beag PTHR12765:SF5 RED PROTEIN IK FACTOR CYTOKINE IK PROTEIN RED primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 cytokine#PC00083 DROME|FlyBase=FBgn0038894|UniProtKB=Q9VD91 Q9VD91 Jhbp16 PTHR11008:SF15 PROTEIN TAKEOUT-LIKE PROTEIN JUVENILE HORMONE BINDING PROTEIN 16 rhythmic process#GO:0048511;circadian rhythm#GO:0007623 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0263607|UniProtKB=Q8IQM9 Q8IQM9 l(3)72Dp PTHR11315:SF0 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE FOLATE GAMMA-GLUTAMYL HYDROLASE catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 protease#PC00190;cysteine protease#PC00081 DROME|FlyBase=FBgn0038092|UniProtKB=Q9VG19 Q9VG19 beat-Vb PTHR21261:SF5 BEAT PROTEIN BEATEN PATH VA, ISOFORM A-RELATED intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0036173|UniProtKB=Q9VTJ8 Q9VTJ8 Tim14 PTHR12763:SF28 FAMILY NOT NAMED GEO10507P1-RELATED DROME|FlyBase=FBgn0031345|UniProtKB=Q9VQ17 Q9VQ17 Dmel\CG18132 PTHR45672:SF3 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 DROME|FlyBase=FBgn0038304|UniProtKB=Q9VFB6 Q9VFB6 Dmel\CG12241 PTHR22957:SF681 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 3 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 DROME|FlyBase=FBgn0038449|UniProtKB=Q9VES7 Q9VES7 Dmel\CG17562 PTHR11011:SF60 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579 DROME|FlyBase=FBgn0039020|UniProtKB=Q9VCU5 Q9VCU5 CG17141 PTHR45782:SF4 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 ribonucleoprotein complex biogenesis#GO:0022613;mitochondrial large ribosomal subunit assembly#GO:1902775;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;cellular component assembly#GO:0022607;ribosomal large subunit assembly#GO:0000027;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0038582|UniProtKB=Q9VEB5 Q9VEB5 CG7988 PTHR28626:SF3 SRR1-LIKE PROTEIN SRR1-LIKE PROTEIN intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DROME|FlyBase=FBgn0046301|UniProtKB=Q9VNX7 Q9VNX7 FBXL12 PTHR16134:SF18 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 17 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to radiation#GO:0009314;cellular process#GO:0009987;regulation of circadian rhythm#GO:0042752;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to external stimulus#GO:0009605;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;photoperiodism#GO:0009648;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;catabolic process#GO:0009056;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0030326|UniProtKB=Q9VYV6 Q9VYV6 BcDNA:LP01642 PTHR39957:SF1 AT09846P1-RELATED AT09846P1-RELATED DROME|FlyBase=FBgn0288967|UniProtKB=Q9V3N5 Q9V3N5 Dmel\CG10793 PTHR23074:SF78 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;meiotic cell cycle#GO:0051321;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0037697|UniProtKB=Q9VHD2 Q9VHD2 GstZ2 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 isomerase#PC00135 DROME|FlyBase=FBgn0031844|UniProtKB=Q9VMA4 Q9VMA4 Dmel\CG13771 PTHR12655:SF10 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0052832|UniProtKB=Q8INZ7 Q8INZ7 Mpc2c PTHR14154:SF154 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 intracellular transport#GO:0046907;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039 cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0264341|UniProtKB=M9PB26 M9PB26 Dmel\CG43797 PTHR22802:SF396 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN binding#GO:0005488;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0034542|UniProtKB=A1ZBY1 A1ZBY1 Fem-1 PTHR24173:SF92 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG B enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0034720|UniProtKB=A8DYM0 A8DYM0 Liprin-gamma PTHR12776:SF1 KAZRIN-RELATED KAZRIN DROME|FlyBase=FBgn0033017|UniProtKB=Q7JZ62 Q7JZ62 Dmel\CG10465 PTHR11145:SF8 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER RE57120P scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031723|UniProtKB=Q9VMP1 Q9VMP1 bs11h10.y1 PTHR23247:SF2 NY-REN-41 ANTIGEN L15 -RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 34 DROME|FlyBase=FBgn0052016|UniProtKB=Q8IH18 Q8IH18 4E-T PTHR12269:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER transporter#PC00227 DROME|FlyBase=FBgn0013334|UniProtKB=Q960T2 Q960T2 Sap47 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of fat cell differentiation#GO:0045600;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;signaling#GO:0023052;TORC2 signaling#GO:0038203;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;TOR signaling#GO:0031929;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;synapse#GO:0045202;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DROME|FlyBase=FBgn0023530|UniProtKB=Q9W569 Q9W569 EG:171E4.4 PTHR31493:SF1 NAZO FAMILY MEMBER PROTEIN C19ORF12 intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;metabolic process#GO:0008152;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;autophagy#GO:0006914;cellular process#GO:0009987;process utilizing autophagic mechanism#GO:0061919;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;catabolic process#GO:0009056;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0086372|UniProtKB=Q9VI75 Q9VI75 lap PTHR22951:SF115 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;clathrin binding#GO:0030276;SNARE binding#GO:0000149;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;organelle organization#GO:0006996;cellular component organization#GO:0016043;membrane organization#GO:0061024;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;clathrin-coated vesicle#GO:0030136;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;synaptic vesicle#GO:0008021;vesicle#GO:0031982;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 vesicle coat protein#PC00235 DROME|FlyBase=FBgn0051683|UniProtKB=Q9Y168 Q9Y168 BcDNA.GH02384 PTHR11440:SF114 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED BCDNA.GH02384 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 transferase#PC00220;acyltransferase#PC00042 DROME|FlyBase=FBgn0029903|UniProtKB=D6W4T8 D6W4T8 pod1 PTHR10856:SF20 CORONIN CORONIN-7 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization#GO:0016043;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cell motility#GO:0048870;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;positive regulation of signaling#GO:0023056;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015 actin filament#GO:0005884;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0023511|UniProtKB=M9PG98 M9PG98 Edem1 PTHR45679:SF10 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;carbohydrate derivative metabolic process#GO:1901135;cell communication#GO:0007154;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycoprotein metabolic process#GO:0009100;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0011589|UniProtKB=A1ZB14 A1ZB14 Elk PTHR10217:SF637 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL EAG-LIKE K[+] CHANNEL, ISOFORM A gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0030367|UniProtKB=Q9VYQ7 Q9VYQ7 Cyp311a1 PTHR24291:SF213 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4C3-RELATED oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0267975|UniProtKB=A0A0B4KGG5 A0A0B4KGG5 vib PTHR10658:SF11 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN VIBRATOR, ISOFORM B transporter#PC00227 DROME|FlyBase=FBgn0261380|UniProtKB=Q9VGW9 Q9VGW9 mRpL37 PTHR15889:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L37 LARGE RIBOSOMAL SUBUNIT PROTEIN ML37 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ribosomal protein#PC00202 DROME|FlyBase=FBgn0030954|UniProtKB=Q7M3J6 Q7M3J6 CCKLR-17D3 PTHR24238:SF84 G-PROTEIN COUPLED RECEPTOR CHOLECYSTOKININ-LIKE RECEPTOR AT 17D1-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0027524|UniProtKB=Q9XZ19 Q9XZ19 Ski8 PTHR44090:SF1 WD REPEAT-CONTAINING PROTEIN 61 SUPERKILLER COMPLEX PROTEIN 8 membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0086130|UniProtKB=Q9VPT3 Q9VPT3 Dbp21E2 PTHR24031:SF421 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX28-RELATED protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;mitochondrial large ribosomal subunit assembly#GO:1902775;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mitochondrial ribosome assembly#GO:0061668;cellular component assembly#GO:0022607;ribosomal large subunit assembly#GO:0000027;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0050460|UniProtKB=A1ZAP8 A1ZAP8 CG15607 PTHR13555:SF5 C2H2 ZINC FINGER CGI-62-RELATED C2HC-TYPE ZINC-FINGER DOMAIN-CONTAINING PROTEIN C2H2 zinc finger transcription factor#PC00248 DROME|FlyBase=FBgn0038018|UniProtKB=Q9VGA2 Q9VGA2 Tim17a1 PTHR10485:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 AT05822P-RELATED transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 DROME|FlyBase=FBgn0026056|UniProtKB=Q9VDG2 Q9VDG2 Rlip PTHR12783:SF6 RALA BINDING PROTEIN 1 RALBP1 RALA-BINDING PROTEIN 1 receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;vesicle-mediated transport#GO:0016192;signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 G-protein modulator#PC00022;GTPase-activating protein#PC00257 DROME|FlyBase=FBgn0030011|UniProtKB=Q9W3J1 Q9W3J1 Gbeta5 PTHR19850:SF36 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;signaling adaptor activity#GO:0035591 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494 G-protein#PC00020;heterotrimeric G-protein#PC00117;protein-binding activity modulator#PC00095 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta5L#P00748;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;PI3 kinase pathway#P00048>Gbetagamma#P01188;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085 DROME|FlyBase=FBgn0031803|UniProtKB=Q9VME8 Q9VME8 ppk14 PTHR11690:SF288 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0004895|UniProtKB=Q02360 Q02360 FoxL1 PTHR11829:SF384 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN L1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0014019|UniProtKB=P91657 P91657 Rh5 PTHR24240:SF58 OPSIN OPSIN RH5 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606;biological regulation#GO:0065007;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to radiation#GO:0071478;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0051852|UniProtKB=Q9VJZ5 Q9VJZ5 Tap42 PTHR10933:SF9 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN BINDING PROTEIN 1 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 chaperone#PC00072 DROME|FlyBase=FBgn0024194|UniProtKB=Q9VZU2 Q9VZU2 rasp PTHR13285:SF26 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE RASP acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 acyltransferase#PC00042 DROME|FlyBase=FBgn0033960|UniProtKB=B7YZH1 B7YZH1 Dmel\CG10151 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0040705|UniProtKB=Q9VR00 Q9VR00 ND-B8 PTHR12878:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0038565|UniProtKB=Q9VED6 Q9VED6 Dmel\CG7794 PTHR11588:SF530 TUBULIN AT04270P structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265 cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 DROME|FlyBase=FBgn0033326|UniProtKB=A1Z7I2 A1Z7I2 Dmel\CG14743 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 DROME|FlyBase=FBgn0039544|UniProtKB=Q2PDP6 Q2PDP6 Dmel\CG12877 PTHR12801:SF115 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED FI18136P1-RELATED hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;hydrolase activity, acting on ester bonds#GO:0016788 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>RNase H#P00538 DROME|FlyBase=FBgn0265190|UniProtKB=Q9VC10 Q9VC10 PIG-S PTHR21072:SF13 GPI TRANSAMIDASE COMPONENT PIG-S GPI-ANCHOR TRANSAMIDASE COMPONENT PIGS protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchored protein biosynthesis#GO:0180046;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0030894|UniProtKB=Q9VWY7 Q9VWY7 Mvb12 PTHR31612:SF2 MULTIVESICULAR BODY SUBUNIT 12A MULTIVESICULAR BODY SUBUNIT 12A metabolic process#GO:0008152;intracellular transport#GO:0046907;macromolecule catabolic process#GO:0009057;vacuolar transport#GO:0007034;transport#GO:0006810;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;regulation of signaling#GO:0023051;localization#GO:0051179;cellular localization#GO:0051641;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;cytosol#GO:0005829 DROME|FlyBase=FBgn0264389|UniProtKB=Q9VXY9 Q9VXY9 opm PTHR22811:SF59 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN GOLD DOMAIN-CONTAINING PROTEIN-RELATED cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;vesicle coat protein#PC00235 DROME|FlyBase=FBgn0082831|UniProtKB=A0A0B4K6G3 A0A0B4K6G3 pps PTHR11477:SF51 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN PROTEIN PARTNER OF SNF, ISOFORM B general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0040364|UniProtKB=Q9V3I0 Q9V3I0 EG:BACR42I17.2 PTHR20997:SF2 EG:BACR42I17.2 PROTEIN-RELATED EG:BACR42I17.2 PROTEIN-RELATED DROME|FlyBase=FBgn0037741|UniProtKB=Q9VH80 Q9VH80 Tti1 PTHR18460:SF3 TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER TELO2-INTERACTING PROTEIN 1 HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030991|UniProtKB=Q9VWL3 Q9VWL3 Dmel\CG7453 PTHR16021:SF13 MANSC DOMAIN CONTAINING PROTEIN 1 EARTHBOUND 1-RELATED DROME|FlyBase=FBgn0036945|UniProtKB=Q9VW87 Q9VW87 Ssk PTHR36692:SF3 PROTEIN SNAKESKIN PROTEIN SNAKESKIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 DROME|FlyBase=FBgn0029514|UniProtKB=Q9W0F9 Q9W0F9 312 PTHR21043:SF0 IOJAP SUPERFAMILY ORTHOLOG MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1 ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488 protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;mitochondrial large ribosomal subunit assembly#GO:1902775;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;mitochondrial ribosome assembly#GO:0061668;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;ribosomal large subunit assembly#GO:0000027;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0063261|UniProtKB=Q7JQ02 Q7JQ02 Ubx PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991 microtubule or microtubule-binding cytoskeletal protein#PC00157 DROME|FlyBase=FBgn0261361|UniProtKB=Q9VW35 Q9VW35 Trpml PTHR12127:SF25 MUCOLIPIN SD02261P passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227;ion channel#PC00133 DROME|FlyBase=FBgn0032049|UniProtKB=Q9VLK3 Q9VLK3 Bace PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987 protease#PC00190;aspartic protease#PC00053 DROME|FlyBase=FBgn0034321|UniProtKB=Q7K174 Q7K174 Dmel\CG14502 PTHR21112:SF0 CHEMOSENSORY PROTEIN A 29A-RELATED CHEMOSENSORY PROTEIN A 29A-RELATED DROME|FlyBase=FBgn0030669|UniProtKB=Q9VXR8 Q9VXR8 Immp1 PTHR12383:SF16 PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1 protease#PC00190;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0051089|UniProtKB=Q9VBK6 Q9VBK6 CG5990 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 lipase#PC00143;hydrolase#PC00121 DROME|FlyBase=FBgn0038783|UniProtKB=Q7KSB4 Q7KSB4 Dmel\CG4367 PTHR21113:SF14 AGAP001705-PA LP24064P DROME|FlyBase=FBgn0034072|UniProtKB=A0A0C4DHF6 A0A0C4DHF6 Dg PTHR21559:SF21 DYSTROGLYCAN-RELATED DYSTROGLYCAN 1 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;morphogenesis of an epithelium#GO:0002009;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;axon guidance#GO:0007411;axon development#GO:0061564;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;system development#GO:0048731 sarcolemma#GO:0042383;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0001099|UniProtKB=P22468 P22468 gdl PTHR13054:SF2 DIGEORGE SYNDROME CRITICAL REGION 6 DGCR6 FAMILY MEMBER PROTEIN DGCR6 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0027587|UniProtKB=X2JAG8 X2JAG8 Prp4k PTHR24058:SF103 DUAL SPECIFICITY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0263600|UniProtKB=P54358 P54358 PolD1 PTHR10322:SF23 DNA POLYMERASE CATALYTIC SUBUNIT DNA POLYMERASE DELTA CATALYTIC SUBUNIT hydrolase activity#GO:0016787;DNA-directed DNA polymerase activity#GO:0003887;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;transferase activity#GO:0016740;DNA exonuclease activity#GO:0004529;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408 cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;replisome#GO:0030894;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575 DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 DROME|FlyBase=FBgn0029608|UniProtKB=Q9W503 Q9W503 Dmel\CG3091 PTHR10174:SF222 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED GH10083P-RELATED small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 DROME|FlyBase=FBgn0042627|UniProtKB=M9PB21 M9PB21 FASN2 PTHR43775:SF37 FATTY ACID SYNTHASE FATTY ACID SYNTHASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 DROME|FlyBase=FBgn0039598|UniProtKB=Q9VAT7 Q9VAT7 aqrs PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0032720|UniProtKB=Q9VJ38 Q9VJ38 mRpL13 PTHR11545:SF45 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 negative regulation of translation#GO:0017148;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 DROME|FlyBase=FBgn0038531|UniProtKB=Q9VEH4 Q9VEH4 Dmel\CG14325 PTHR24107:SF20 YNEIN REGULATORY COMPLEX SUBUNIT 5 DYNEIN REGULATORY COMPLEX SUBUNIT 5 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 DROME|FlyBase=FBgn0053505|UniProtKB=Q8MSW9 Q8MSW9 U3-55K PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DROME|FlyBase=FBgn0261437|UniProtKB=Q7KTH8 Q7KTH8 CSN8 PTHR13339:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0036765|UniProtKB=Q9VVM1 Q9VVM1 Dmel\CG7408 PTHR10342:SF264 ARYLSULFATASE MIP05773P-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 DROME|FlyBase=FBgn0038199|UniProtKB=Q4V4I9 Q4V4I9 CCHa1 PTHR35980:SF1 NEUROPEPTIDE CCHAMIDE-1-RELATED NEUROPEPTIDE CCHAMIDE-1-RELATED DROME|FlyBase=FBgn0053766|UniProtKB=Q4ABI0 Q4ABI0 CG14458 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0039343|UniProtKB=Q9VBQ3 Q9VBQ3 Dmel\CG5111 PTHR12948:SF3 NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN NEDD8 ULTIMATE BUSTER 1 regulation of protein catabolic process#GO:0042176;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090 DROME|FlyBase=FBgn0031784|UniProtKB=Q8T4D4 Q8T4D4 Tssk2 PTHR24343:SF605 SERINE/THREONINE KINASE AT03158P phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 DROME|FlyBase=FBgn0038037|UniProtKB=Q9VG82 Q9VG82 Cyp9f2 PTHR24292:SF54 CYTOCHROME P450 CYTOCHROME P450 9B1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0038274|UniProtKB=Q9VFE7 Q9VFE7 Nup93-2 PTHR11225:SF4 NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP93 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein transport#GO:0015031;protein import into nucleus#GO:0006606;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;gene expression#GO:0010467;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular protein transport#GO:0006886;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 DROME|FlyBase=FBgn0034049|UniProtKB=Q0E961 Q0E961 bdg PTHR11616:SF323 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT TRANSPORTER BEDRAGGLED carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;glycine transport#GO:0015816;monoatomic cation transport#GO:0006812;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 DROME|FlyBase=FBgn0050372|UniProtKB=A1Z7A6 A1Z7A6 Asap PTHR45854:SF3 ASAP FAMILY MEMBER ARFGAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0035375|UniProtKB=Q6WV16 Q6WV16 Pgant6 PTHR11675:SF134 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;transferase#PC00220 DROME|FlyBase=FBgn0017429|UniProtKB=Q9VSM4 Q9VSM4 Dmel\CG5989 PTHR14009:SF13 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0030776|UniProtKB=Q9VXC6 Q9VXC6 Dmel\CG4653 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0004394|UniProtKB=Q9VK71 Q9VK71 pdm2 PTHR11636:SF140 POU DOMAIN POU DOMAIN PROTEIN 2, ISOFORM B-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0262599|UniProtKB=Q9VKN9 Q9VKN9 SmydA-3 PTHR46455:SF7 SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A RE12806P nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0031434|UniProtKB=Q8SYK5 Q8SYK5 insv PTHR35346:SF1 BEN DOMAIN-CONTAINING PROTEIN 6 BEN DOMAIN-CONTAINING PROTEIN 6 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of Notch signaling pathway#GO:0045746;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of cell differentiation#GO:0045597;negative regulation of cellular process#GO:0048523;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of neuron differentiation#GO:0045664;negative regulation of response to stimulus#GO:0048585 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0030276|UniProtKB=Q9VZ20 Q9VZ20 Dlic PTHR12688:SF5 DYNEIN LIGHT INTERMEDIATE CHAIN DYNEIN LIGHT INTERMEDIATE CHAIN binding#GO:0005488;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;microtubule-based movement#GO:0007018;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 DROME|FlyBase=FBgn0011705|UniProtKB=O44252 O44252 rost PTHR12242:SF49 OS02G0130600 PROTEIN-RELATED IP08657P-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0040068|UniProtKB=Q9NHV9 Q9NHV9 Vav PTHR45818:SF3 PROTEIN VAV PROTEIN VAV guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;cell migration#GO:0016477;cell motility#GO:0048870;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 PDGF signaling pathway#P00047>Vav#P01169 DROME|FlyBase=FBgn0037013|UniProtKB=Q9VPD0 Q9VPD0 Dmel\CG13250 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0262514|UniProtKB=Q9VFE5 Q9VFE5 VhaPPA1-2 PTHR10263:SF18 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 21 KDA PROTEOLIPID SUBUNIT C'' cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 DROME|FlyBase=FBgn0037561|UniProtKB=Q9VHU1 Q9VHU1 CG9630 PTHR24031:SF2 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX55 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 RNA helicase#PC00032;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0261109|UniProtKB=Q9VUR1 Q9VUR1 mrn PTHR13152:SF0 TFIIH, POLYPEPTIDE 4 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4 DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974 nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transcription factor TFIIH core complex#GO:0000439;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIH complex#P00664;Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392 DROME|FlyBase=FBgn0004431|UniProtKB=P37161 P37161 LysX PTHR11407:SF63 LYSOZYME C LYSOZYME lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824 glycosidase#PC00110 DROME|FlyBase=FBgn0036833|UniProtKB=Q9VVV1 Q9VVV1 CT12789 PTHR13966:SF19 ENDONUCLEASE RELATED DNA_RNA NON-SPECIFIC ENDONUCLEASE DOMAIN-CONTAINING PROTEIN-RELATED endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;programmed cell death#GO:0012501;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219 organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0261046|UniProtKB=Q7KSE9 Q7KSE9 Dscam3 PTHR10075:SF142 BASIGIN RELATED CELL ADHESION MOLECULE DSCAM2-RELATED central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731 cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0031986|UniProtKB=Q9VLT0 Q9VLT0 GalT5 PTHR11214:SF379 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE-RELATED glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 transferase#PC00220;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0043457|UniProtKB=B7Z0N0 B7Z0N0 LD05530 PTHR21505:SF8 MADF DOMAIN-CONTAINING PROTEIN-RELATED DPT-YFP REPRESSOR BY OVEREXPRESSION, ISOFORM D-RELATED DROME|FlyBase=FBgn0033636|UniProtKB=A8DYA3 A8DYA3 tou PTHR45915:SF9 TRANSCRIPTION INTERMEDIARY FACTOR TOUTATIS, ISOFORM E transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0032816|UniProtKB=Q8ST61 Q8ST61 Nf-YB PTHR11064:SF9 CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 DROME|FlyBase=FBgn0287478|UniProtKB=B7YZU4 B7YZU4 Camta PTHR23335:SF1 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR, ISOFORM F double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0004463|UniProtKB=P25167 P25167 Polr3B PTHR20856:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 snRNA transcription#GO:0009301;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase III#GO:0042796;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0021906|UniProtKB=Q9VQ29 Q9VQ29 RFeSP PTHR10134:SF50 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex III#GO:0045275 DROME|FlyBase=FBgn0262114|UniProtKB=Q4Z8K6 Q4Z8K6 RanBPM PTHR12864:SF49 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEINS 9_10 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0023521|UniProtKB=O46079 O46079 EG:39E1.2 PTHR12435:SF2 FAMILY NOT NAMED PROTEIN KTI12 HOMOLOG RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 DROME|FlyBase=FBgn0036046|UniProtKB=Q9VT51 Q9VT51 Ilp2 PTHR13647:SF4 INSULIN-LIKE PEPTIDE 2-RELATED INSULIN-LIKE PEPTIDE 1-RELATED DROME|FlyBase=FBgn0032429|UniProtKB=Q9VK90 Q9VK90 BcDNA:RE36920 PTHR19424:SF0 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to stress#GO:0033554;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;heat acclimation#GO:0010286;cellular response to heat#GO:0034605;response to heat#GO:0009408;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0029121|UniProtKB=Q9U1H8 Q9U1H8 Sras PTHR13046:SF0 PROTEASE U48 CAAX PRENYL PROTEASE RCE1 CAAX PRENYL PROTEASE 2 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 metalloprotease#PC00153 DROME|FlyBase=FBgn0259226|UniProtKB=A0A0B4LEX9 A0A0B4LEX9 Dmel\CG42326 PTHR47327:SF13 FI18240P1-RELATED APPLE DOMAIN-CONTAINING PROTEIN anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502 DROME|FlyBase=FBgn0035374|UniProtKB=Q9VZX6 Q9VZX6 mRpS35 PTHR13490:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN MS35 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313 translational protein#PC00263;ribosomal protein#PC00202 DROME|FlyBase=FBgn0266449|UniProtKB=Q9V447 Q9V447 Kr-h2 PTHR12703:SF4 TRANSMEMBRANE PROTEIN 33 TRANSMEMBRANE PROTEIN 33 endoplasmic reticulum membrane organization#GO:0090158;nuclear envelope organization#GO:0006998;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nuclear membrane organization#GO:0071763;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum tubular network organization#GO:0071786 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0031877|UniProtKB=Q9VM58 Q9VM58 Hmgcl PTHR42738:SF7 HYDROXYMETHYLGLUTARYL-COA LYASE HYDROXYMETHYLGLUTARYL-COA LYASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 lyase#PC00144 DROME|FlyBase=FBgn0036618|UniProtKB=Q9VV45 Q9VV45 Cpr72Eb PTHR12236:SF102 STRUCTURAL CONSTITUENT OF CUTICLE CRYSTALLIN, ISOFORM A-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DROME|FlyBase=FBgn0050016|UniProtKB=A1Z8C9 A1Z8C9 anon-AE003828.1 PTHR10395:SF7 URICASE AND TRANSTHYRETIN-RELATED 5-HYDROXYISOURATE HYDROLASE small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144 hydrolase#PC00121 DROME|FlyBase=FBgn0039087|UniProtKB=Q9VCL3 Q9VCL3 Ugt303B2 PTHR48043:SF145 EG:EG0003.4 PROTEIN-RELATED FI06409P-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740 DROME|FlyBase=FBgn0035064|UniProtKB=Q9W107 Q9W107 TyrRS-m PTHR11766:SF0 TYROSYL-TRNA SYNTHETASE TYROSINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 DROME|FlyBase=FBgn0085369|UniProtKB=A0AVV3 A0AVV3 Drgx PTHR24329:SF582 HOMEOBOX PROTEIN ARISTALESS DORSAL ROOT GANGLIA HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0051294|UniProtKB=Q8IND4 Q8IND4 NEST:bs25d10 PTHR46540:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 12 TETRATRICOPEPTIDE REPEAT PROTEIN 12 cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;sperm motility#GO:0097722;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 DROME|FlyBase=FBgn0039585|UniProtKB=Q9VAV6 Q9VAV6 Myst5 PTHR10615:SF82 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT8 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0003011|UniProtKB=Q9VDU9 Q9VDU9 ort PTHR18945:SF908 NEUROTRANSMITTER GATED ION CHANNEL HISTAMINE-GATED CHLORIDE CHANNEL ALPHA1 SUBUNIT monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 DROME|FlyBase=FBgn0027572|UniProtKB=Q7KML2 Q7KML2 Acox1 PTHR10909:SF250 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE-RELATED oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;fatty acid binding#GO:0005504;lipid binding#GO:0008289;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;organic acid binding#GO:0043177;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0000576|UniProtKB=P18488 P18488 ems PTHR24340:SF73 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN BAGPIPE-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 DROME|FlyBase=FBgn0039113|UniProtKB=Q9VCI4 Q9VCI4 udt PTHR22255:SF1 LP06548P LD32918P DROME|FlyBase=FBgn0038916|UniProtKB=Q9VD64 Q9VD64 dnd PTHR45697:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0034769|UniProtKB=Q9W208 Q9W208 Obp58c PTHR21066:SF15 ODORANT-BINDING PROTEIN 59A-RELATED GH25962P-RELATED DROME|FlyBase=FBgn0037498|UniProtKB=Q9VI96 Q9VI96 Dmel\CG10029 PTHR46295:SF1 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 DROME|FlyBase=FBgn0069354|UniProtKB=Q9VKP2 Q9VKP2 Porin2 PTHR11743:SF70 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL GH26960P-RELATED passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267 intracellular transport#GO:0046907;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020 voltage-gated ion channel#PC00241 DROME|FlyBase=FBgn0034655|UniProtKB=Q9W2D7 Q9W2D7 Dmel\CG10307 PTHR45752:SF215 LEUCINE-RICH REPEAT-CONTAINING GH17740P-RELATED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030451|UniProtKB=Q9VYG8 Q9VYG8 Dmel\CG15717 PTHR21644:SF0 AT02555P-RELATED AT02555P-RELATED DROME|FlyBase=FBgn0053234|UniProtKB=A8JNI7 A8JNI7 Dmel\CG33234 PTHR23511:SF37 SYNAPTIC VESICLE GLYCOPROTEIN 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 DROME|FlyBase=FBgn0014073|UniProtKB=Q9VZA8 Q9VZA8 Tie PTHR24416:SF655 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0034707|UniProtKB=Q9W278 Q9W278 MED16 PTHR13224:SF6 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DROME|FlyBase=FBgn0032871|UniProtKB=Q9VIL1 Q9VIL1 38D.27 PTHR15664:SF21 C20ORF30 PROTEIN TRANSMEMBRANE PROTEIN 230 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 DROME|FlyBase=FBgn0039734|UniProtKB=Q9VAC5 Q9VAC5 Tace PTHR45702:SF6 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;biological regulation#GO:0065007;membrane protein ectodomain proteolysis#GO:0006509;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;cell communication#GO:0007154;protein metabolic process#GO:0019538;proteolysis#GO:0006508;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>TACE#P00147;Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>TACE#P00092 DROME|FlyBase=FBgn0038083|UniProtKB=Q9VG29 Q9VG29 Ugt37A3 PTHR48043:SF159 EG:EG0003.4 PROTEIN-RELATED FI03416P-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 DROME|FlyBase=FBgn0033929|UniProtKB=Q960E8 Q960E8 Tfb1 PTHR12856:SF0 TRANSCRIPTION INITIATION FACTOR IIH-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1 response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 DROME|FlyBase=FBgn0020235|UniProtKB=O01666 O01666 ATPsyngamma PTHR11693:SF45 ATP SYNTHASE GAMMA CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT GAMMA, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;organophosphate biosynthetic process#GO:0090407 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966 ATP synthase#PC00002 ATP synthesis#P02721>F1 gamma#P02796 DROME|FlyBase=FBgn0003870|UniProtKB=P42282 P42282 ttk PTHR23110:SF118 BTB DOMAIN TRANSCRIPTION FACTOR PROTEIN TRAMTRACK, ALPHA ISOFORM regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0034519|UniProtKB=A1ZBV5 A1ZBV5 BORCS7 PTHR31397:SF1 BLOC-1-RELATED COMPLEX SUBUNIT 7 BORSC7 BLOC-1-RELATED COMPLEX SUBUNIT 7 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0038568|UniProtKB=Q9VED1 Q9VED1 Dmel\CG14315 PTHR41152:SF8 AT26438P-RELATED AT26438P-RELATED DROME|FlyBase=FBgn0030699|UniProtKB=Q9VXN3 Q9VXN3 Dmel\CG8578 PTHR19212:SF0 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LD07988P gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0033443|UniProtKB=Q7K330 Q7K330 DmNAT5 PTHR11616:SF339 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293 glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 DROME|FlyBase=FBgn0031407|UniProtKB=Q9VQA2 Q9VQA2 Dmel\CG4270 PTHR10334:SF565 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 DROME|FlyBase=FBgn0037370|UniProtKB=Q8I725 Q8I725 Dmel\CG1236 PTHR10996:SF277 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 DROME|FlyBase=FBgn0038252|UniProtKB=Q8MSC4 Q8MSC4 BigH1 PTHR13275:SF4 YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;Swr1 complex#GO:0000812;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0026374|UniProtKB=Q9XYY9 Q9XYY9 Rhp PTHR23031:SF15 RHOPHILIN LD12055P biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;negative regulation of biological process#GO:0048519;regulation of actin filament bundle assembly#GO:0032231;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of cytoskeleton organization#GO:0051494 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0038746|UniProtKB=Q9VDS6 Q9VDS6 Surf6 PTHR14369:SF0 SURFEIT LOCUS PROTEIN 6 SURFEIT LOCUS PROTEIN 6 nucleic acid binding#GO:0003676;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;molecular condensate scaffold activity#GO:0140693;RNA binding#GO:0003723 cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0052479|UniProtKB=Q9W0L7 Q9W0L7 Usp10 PTHR13328:SF5 NEGATIVE ELONGATION FACTOR A NELF-A UBIQUITINYL HYDROLASE 1 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;positive regulation of response to stimulus#GO:0048584;positive regulation of Notch signaling pathway#GO:0045747;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of signal transduction#GO:0009967 DROME|FlyBase=FBgn0039417|UniProtKB=Q9VBG6 Q9VBG6 CG6073 PTHR13387:SF9 PROTEIN HGH1 HOMOLOG CO-CHAPERONE PROTEIN HGH1 HOMOLOG DROME|FlyBase=FBgn0034643|UniProtKB=A0A0B4KFE8 A0A0B4KFE8 Dmel\CG10321 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0043900|UniProtKB=Q9V9W8 Q9V9W8 pygo PTHR23194:SF16 PYGOPUS PROTEIN PYGOPUS transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>Pygo#P01464 DROME|FlyBase=FBgn0040502|UniProtKB=Q6NMY2 Q6NMY2 BEST:GH10831 PTHR22802:SF456 C-TYPE LECTIN SUPERFAMILY MEMBER AT17652P-RELATED binding#GO:0005488;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 DROME|FlyBase=FBgn0004797|UniProtKB=Q960U8 Q960U8 mdy PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 DROME|FlyBase=FBgn0010382|UniProtKB=P54733 P54733 CycE PTHR10177:SF344 CYCLINS G1_S-SPECIFIC CYCLIN-E enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 regulation of mitotic cell cycle phase transition#GO:1901990;mitotic cell cycle phase transition#GO:0044772;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin E#P04664;Cell cycle#P00013>Cyclin E#P00483;Cell cycle#P00013>CdkC#P00489;p53 pathway#P00059>Cyclin E#P04610 DROME|FlyBase=FBgn0002183|UniProtKB=Q8IRG6 Q8IRG6 dre4 PTHR13980:SF15 CDC68 RELATED FACT COMPLEX SUBUNIT SPT16 molecular carrier activity#GO:0140104;binding#GO:0005488;chromatin binding#GO:0003682;protein carrier activity#GO:0140597;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0051220|UniProtKB=Q8IN70 Q8IN70 CG16731 PTHR24260:SF144 AT07769P-RELATED CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED Toll pathway-drosophila#P06217>SPE#P06340 DROME|FlyBase=FBgn0038774|UniProtKB=Q9I7J0 Q9I7J0 Dmel\CG5023 PTHR47385:SF22 CALPONIN GH21596P protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 DROME|FlyBase=FBgn0031740|UniProtKB=Q9VMM3 Q9VMM3 Dmel\CG7239 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 DROME|FlyBase=FBgn0053474|UniProtKB=A1Z891 A1Z891 Pex11g PTHR20990:SF1 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11C cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;organelle organization#GO:0006996;cellular component organization#GO:0016043;peroxisome organization#GO:0007031;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0267849|UniProtKB=Q7K0X9 Q7K0X9 Syx7 PTHR19957:SF411 SYNTAXIN LD23667P SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;synapse#GO:0045202;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cell junction#GO:0030054;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 DROME|FlyBase=FBgn0037487|UniProtKB=Q9VI80 Q9VI80 thw PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0035020|UniProtKB=Q0E8W6 Q0E8W6 BcDNA:AT28250 PTHR31019:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 14 SMALL INTEGRAL MEMBRANE PROTEIN 14 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 DROME|FlyBase=FBgn0041605|UniProtKB=Q8IPM8 Q8IPM8 cpx PTHR16705:SF4 COMPLEXIN COMPLEXIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulated exocytosis#GO:0045055;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 axon terminus#GO:0043679;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cell projection#GO:0042995;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0004882|UniProtKB=Q9VCN7 Q9VCN7 orb PTHR12566:SF9 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1 translation factor activity#GO:0180051;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723 regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of translation#GO:0017148 intracellular organelle#GO:0043229;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;nucleus#GO:0005634;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 mRNA polyadenylation factor#PC00146 DROME|FlyBase=FBgn0015038|UniProtKB=Q9V4I0 Q9V4I0 Cyp9b1 PTHR24292:SF54 CYTOCHROME P450 CYTOCHROME P450 9B1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0030266|UniProtKB=Q9VZ30 Q9VZ30 Dmel\CG11122 PTHR34491:SF134 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 62 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 DROME|FlyBase=FBgn0027594|UniProtKB=Q9W0A0 Q9W0A0 drpr PTHR24035:SF109 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN PROTEIN DRAPER membrane invagination#GO:0010324;transport#GO:0006810;phagocytosis#GO:0006909;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;endocytosis#GO:0006897 extracellular matrix protein#PC00102 DROME|FlyBase=FBgn0003892|UniProtKB=P18502 P18502 ptc PTHR46022:SF1 PROTEIN PATCHED PROTEIN PATCHED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515 negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 Hedgehog signaling pathway#P00025>Patched#P00689 DROME|FlyBase=FBgn0038588|UniProtKB=Q9VEA9 Q9VEA9 Dmel\CG7156 PTHR15508:SF8 RIBOSOMAL PROTEIN S6 KINASE LD24550P non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0031826|UniProtKB=Q9VMC4 Q9VMC4 Dmel\CG9550 PTHR10704:SF44 CARBOHYDRATE SULFOTRANSFERASE LD35051P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 transferase#PC00220;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0038108|UniProtKB=Q9VG05 Q9VG05 Dmel\CG7518 PTHR15109:SF4 AGAP004327-PA FAM193 C-TERMINAL DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0025336|UniProtKB=O77477 O77477 LD24471 PTHR21393:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN MS27 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 DROME|FlyBase=FBgn0261673|UniProtKB=Q7JR72 Q7JR72 nemy PTHR10106:SF24 CYTOCHROME B561-RELATED NO EXTENDED MEMORY, ISOFORM A catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0263986|UniProtKB=Q9VCW2 Q9VCW2 cd PTHR11475:SF141 OXIDASE/PEROXIDASE CARDINAL catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0037184|UniProtKB=Q9VNR9 Q9VNR9 Dmel\CG14450 PTHR21053:SF2 TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;nucleoid#GO:0009295;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645 DROME|FlyBase=FBgn0025833|UniProtKB=A1ZAL4 A1ZAL4 EG:EG0003.1 PTHR12109:SF10 RING FINGER PROTEIN 141-RELATED FI02064P ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DROME|FlyBase=FBgn0050502|UniProtKB=Q8SXY2 Q8SXY2 Fa2h PTHR12863:SF1 FATTY ACID HYDROXYLASE FATTY ACID 2-HYDROXYLASE oxidoreductase#PC00176;hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039909|UniProtKB=Q9V4E0 Q9V4E0 ND-49 PTHR11993:SF48 NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;NADH dehydrogenase activity#GO:0003954 oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 respiratory chain complex I#GO:0045271;organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0038692|UniProtKB=Q9VDY6 Q9VDY6 Polr2M PTHR23171:SF13 GDOWN1 RNA POLYMERASE II SUBUNIT M nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 DROME|FlyBase=FBgn0030795|UniProtKB=Q86LG1 Q86LG1 ppk28 PTHR11690:SF243 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED PICKPOCKET 12-RELATED monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 DROME|FlyBase=FBgn0034657|UniProtKB=Q8MLV1 Q8MLV1 LBR PTHR21257:SF61 DELTA(14)-STEROL REDUCTASE LAMIN-B RECEPTOR oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle inner membrane#GO:0019866;membrane#GO:0016020;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0035964|UniProtKB=Q9VSU6 Q9VSU6 Dhpr PTHR15104:SF0 DIHYDROPTERIDINE REDUCTASE DIHYDROPTERIDINE REDUCTASE heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 DROME|FlyBase=FBgn0035039|UniProtKB=Q9W133 Q9W133 Adck1 PTHR43173:SF19 ABC1 FAMILY PROTEIN AARF DOMAIN-CONTAINING PROTEIN KINASE 1 lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;mitochondrion organization#GO:0007005;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0263993|UniProtKB=M9PGK3 M9PGK3 Dmel\CG43736 PTHR42264:SF3 EPHRIN_REC_LIKE DOMAIN-CONTAINING PROTEIN F-BOX DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0003187|UniProtKB=Q23989 Q23989 qua PTHR11977:SF57 VILLIN VILLIN-LIKE PROTEIN QUAIL phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;actin binding#GO:0003779;actin filament binding#GO:0051015;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 DROME|FlyBase=FBgn0034307|UniProtKB=Q8SZ15 Q8SZ15 Dmel\CG10914 PTHR46406:SF1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0052006|UniProtKB=Q8IMA2 Q8IMA2 DmCg32006 PTHR11829:SF402 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD3-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 DROME|FlyBase=FBgn0023523|UniProtKB=O46077 O46077 Or2a PTHR21137:SF35 ODORANT RECEPTOR ODORANT RECEPTOR 19A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 DROME|FlyBase=FBgn0029503|UniProtKB=Q9VCC0 Q9VCC0 mora PTHR12621:SF12 CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 centrosome cycle#GO:0007098;cellular process#GO:0009987;cell cycle process#GO:0022402;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0030945|UniProtKB=Q9VWS0 Q9VWS0 Ing3 PTHR10333:SF114 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0011741|UniProtKB=P45890 P45890 Arp6 PTHR11937:SF47 ACTIN ACTIN-RELATED PROTEIN 6 structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;structural molecule activity#GO:0005198;protein-containing complex binding#GO:0044877 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nucleolus organization#GO:0007000 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 actin and actin related protein#PC00039 DROME|FlyBase=FBgn0014903|UniProtKB=Q9W5B5 Q9W5B5 Dmel\CG14630 PTHR10696:SF58 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED GAMMA-BUTYROBETAINE DIOXYGENASE-RELATED 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biosynthetic process#GO:0009058;carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0051352|UniProtKB=E1JIH3 E1JIH3 Unc-115a PTHR24213:SF9 ACTIN-BINDING LIM PROTEIN UNCOORDINATED 115A, ISOFORM B-RELATED actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Axon guidance mediated by netrin#P00009>Ablim#P00358 DROME|FlyBase=FBgn0052483|UniProtKB=Q8IRI8 Q8IRI8 Dmel\CG32483 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 serine protease#PC00203 DROME|FlyBase=FBgn0037533|UniProtKB=A0A0B4KGE4 A0A0B4KGE4 CD98hc PTHR46673:SF1 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN AMINO ACID TRANSPORTER HEAVY CHAIN SLC3A2 nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;branched-chain amino acid transport#GO:0015803;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;alanine transport#GO:0032328;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;L-leucine transport#GO:0015820;L-alpha-amino acid transmembrane transport#GO:1902475;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;apical part of cell#GO:0045177 DROME|FlyBase=FBgn0011676|UniProtKB=Q27571 Q27571 Nos PTHR19384:SF76 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;monooxygenase activity#GO:0004497;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;oxidoreductase activity, acting on NAD(P)H#GO:0016651;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488 metabolic process#GO:0008152;response to lipopolysaccharide#GO:0032496;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to lipid#GO:0033993;arginine metabolic process#GO:0006525;intracellular signaling cassette#GO:0141124;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;small molecule catabolic process#GO:0044282;response to external stimulus#GO:0009605;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to other organism#GO:0051707;amino acid metabolic process#GO:0006520;response to bacterium#GO:0009617;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0032643|UniProtKB=Q9VJD1 Q9VJD1 GCS2beta PTHR12630:SF1 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA-RELATED glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0053626|UniProtKB=A1Z8Z5 A1Z8Z5 Dmel\CG33626 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0033645|UniProtKB=Q7JUW8 Q7JUW8 Dmel\CG13196 PTHR39959:SF2 RE44287P-RELATED RE44287P DROME|FlyBase=FBgn0010040|UniProtKB=Q9VG96 Q9VG96 GstD4 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 DROME|FlyBase=FBgn0031169|UniProtKB=Q9VRG3 Q9VRG3 Dmel\CG1494 PTHR19229:SF278 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 DROME|FlyBase=FBgn0265267|UniProtKB=Q9VX70 Q9VX70 CT41369 PTHR11610:SF149 LIPASE FI01450P-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 DROME|FlyBase=FBgn0035813|UniProtKB=Q9VSA5 Q9VSA5 Dmel\CG8492 PTHR11407:SF76 LYSOZYME C LYSOZYME catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;lysozyme activity#GO:0003796 glycosidase#PC00110 DROME|FlyBase=FBgn0035331|UniProtKB=M9PEC0 M9PEC0 MsR1 PTHR46273:SF15 MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 DROME|FlyBase=FBgn0034183|UniProtKB=A1ZAP0 A1ZAP0 SmydA-6 PTHR46455:SF6 SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A RE22408P-RELATED nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0266137|UniProtKB=Q24563 Q24563 Dop1R2 PTHR24248:SF212 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 DROME|FlyBase=FBgn0259729|UniProtKB=Q9W175 Q9W175 p47 NSFL1 PTHR23333:SF20 UBX DOMAIN CONTAINING PROTEIN GH01724P ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 establishment of organelle localization#GO:0051656;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular localization#GO:0051641;spindle localization#GO:0051653;establishment or maintenance of cell polarity#GO:0007163;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component organization or biogenesis#GO:0071840;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;cell cycle#GO:0007049;establishment of cell polarity#GO:0030010;modification-dependent protein catabolic process#GO:0019941;microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;localization#GO:0051179;organelle localization#GO:0051640;establishment of spindle localization#GO:0051293;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0029853|UniProtKB=Q9W422 Q9W422 Josd PTHR13291:SF0 JOSEPHIN 1, 2 JOSEPHIN-LIKE PROTEIN deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 protein modifying enzyme#PC00260;cysteine protease#PC00081 DROME|FlyBase=FBgn0053773|UniProtKB=Q4AB21 Q4AB21 BP1061 PTHR20898:SF0 DAEDALUS ON 3-RELATED-RELATED DAEDALUS ON 3-RELATED DROME|FlyBase=FBgn0000289|UniProtKB=A8DYD1 A8DYD1 cg PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 DROME|FlyBase=FBgn0034662|UniProtKB=Q8MLU9 Q8MLU9 Dmel\CG13492 PTHR21721:SF26 GH09876P-RELATED DUF753 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0261788|UniProtKB=M9MRX4 M9MRX4 Ank2 PTHR24123:SF33 ANKYRIN REPEAT-CONTAINING ANKYRIN 2, ISOFORM U scaffold/adaptor protein#PC00226 DROME|FlyBase=FBgn0031182|UniProtKB=Q9VRI9 Q9VRI9 Cyp6t1 PTHR24292:SF45 CYTOCHROME P450 CYTOCHROME P450 6G1-RELATED oxidoreductase#PC00176;oxygenase#PC00177 DROME|FlyBase=FBgn0260463|UniProtKB=Q8INN6 Q8INN6 Unc-115b PTHR24213:SF9 ACTIN-BINDING LIM PROTEIN UNCOORDINATED 115A, ISOFORM B-RELATED protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Axon guidance mediated by netrin#P00009>Ablim#P00358 DROME|FlyBase=FBgn0035501|UniProtKB=Q9VZH5 Q9VZH5 SP18 PTHR24253:SF95 TRANSMEMBRANE PROTEASE SERINE CLIP DOMAIN-CONTAINING SERINE PROTEASE catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0014033|UniProtKB=Q9V3H7 Q9V3H7 Sr-CI PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED DROME|FlyBase=FBgn0038180|UniProtKB=Q9VFR3 Q9VFR3 Cht5 PTHR11177:SF144 CHITINASE CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0030148|UniProtKB=Q9W322 Q9W322 Dmel\CG3106 PTHR11161:SF75 O-ACYLTRANSFERASE FI22618P1-RELATED acyltransferase#PC00042 DROME|FlyBase=FBgn0004428|UniProtKB=P37159 P37159 LysE PTHR11407:SF63 LYSOZYME C LYSOZYME hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosidase#PC00110 DROME|FlyBase=FBgn0028691|UniProtKB=Q7KMP8 Q7KMP8 Rpn9 PTHR10539:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541 protease#PC00190;protein modifying enzyme#PC00260 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Parkinson disease#P00049>19S proteasome#P01209 DROME|FlyBase=FBgn0053181|UniProtKB=A8JV32 A8JV32 Dmel\CG33181 PTHR16228:SF26 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 DROME|FlyBase=FBgn0002306|UniProtKB=Q04164 Q04164 sas PTHR11348:SF34 CONNECTIVE TISSUE GROWTH FACTOR-RELATED EPIDERMAL CELL SURFACE RECEPTOR-RELATED protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 DROME|FlyBase=FBgn0033248|UniProtKB=A1Z787 A1Z787 Dic3 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER dicarboxylic acid transmembrane transporter activity#GO:0005310;succinate transmembrane transporter activity#GO:0015141;C4-dicarboxylate transmembrane transporter activity#GO:0015556;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 dicarboxylic acid transport#GO:0006835;phosphate ion transport#GO:0006817;carboxylic acid transmembrane transport#GO:1905039;succinate transport#GO:0015744;cellular process#GO:0009987;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;C4-dicarboxylate transport#GO:0015740 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0034521|UniProtKB=Q60GL7 Q60GL7 Mgat1 PTHR10468:SF12 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0036878|UniProtKB=Q9VW02 Q9VW02 Cpr76Ba PTHR12236:SF76 STRUCTURAL CONSTITUENT OF CUTICLE PUPAL CUTICLE PROTEIN EDG-84A-LIKE PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0026576|UniProtKB=Q9VCE0 Q9VCE0 Pisd PTHR10067:SF6 PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 organophosphate biosynthetic process#GO:0090407;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 decarboxylase#PC00089;lyase#PC00144;metabolite interconversion enzyme#PC00262 DROME|FlyBase=FBgn0039125|UniProtKB=Q9VCG4 Q9VCG4 Ndc1 PTHR13269:SF6 NUCLEOPORIN NDC1 NUCLEOPORIN NDC1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nuclear pore organization#GO:0006999;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967 DROME|FlyBase=FBgn0002914|UniProtKB=P04197 P04197 Myb PTHR45614:SF315 MYB PROTEIN-RELATED MYB PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;mitotic cell cycle#GO:0000278;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell cycle#GO:0007049;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 DROME|FlyBase=FBgn0260468|UniProtKB=Q9VAA6 Q9VAA6 Mia40 PTHR21622:SF0 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;mitochondrial protein import pathway#GO:7770058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740 DROME|FlyBase=FBgn0010786|UniProtKB=Q9W0G4 Q9W0G4 Hmbs PTHR11557:SF0 PORPHOBILINOGEN DEAMINASE PORPHOBILINOGEN DEAMINASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Hydroxymethylbilane synthase#P02983 DROME|FlyBase=FBgn0044323|UniProtKB=D3DML3 D3DML3 Cka PTHR15653:SF0 STRIATIN CONNECTOR OF KINASE TO AP-1, ISOFORM E molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991 DROME|FlyBase=FBgn0029854|UniProtKB=Q8IRR0 Q8IRR0 Dmel\CG3566 PTHR19359:SF14 CYTOCHROME B5 CYTOCHROME B5 heme binding#GO:0020037;binding#GO:0005488;tetrapyrrole binding#GO:0046906 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular organelle#GO:0043229 oxidoreductase#PC00176 DROME|FlyBase=FBgn0036688|UniProtKB=Q9VVD2 Q9VVD2 Fit2 PTHR16160:SF13 FERMITIN 2-RELATED FERMITIN 2-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178 cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-substrate junction#GO:0030055 DROME|FlyBase=FBgn0004619|UniProtKB=Q03445 Q03445 GluRIA PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594 regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 DROME|FlyBase=FBgn0288470|UniProtKB=Q0E8G6 Q0E8G6 Cpsf5 PTHR13047:SF0 PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 DROME|FlyBase=FBgn0038730|UniProtKB=Q9VDU4 Q9VDU4 Acsx1L PTHR24096:SF353 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE X1 L-RELATED ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;lipid metabolic process#GO:0006629;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;organophosphate biosynthetic process#GO:0090407 ligase#PC00142 DROME|FlyBase=FBgn0037490|UniProtKB=Q9VI83 Q9VI83 Dmel\CG10053 PTHR21032:SF0 G PATCH DOMAIN-CONTAINING PROTEIN 11 G PATCH DOMAIN-CONTAINING PROTEIN 11 RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DROME|FlyBase=FBgn0036950|UniProtKB=Q9VW92 Q9VW92 Dmel\CG6996 PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED DROME|FlyBase=FBgn0053169|UniProtKB=Q8SY72 Q8SY72 CG33169 PTHR34644:SF2 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 DROME|FlyBase=FBgn0030501|UniProtKB=Q9VYB0 Q9VYB0 BthD PTHR33638:SF1 SELENOPROTEIN H SELENOPROTEIN H organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DROME|FlyBase=FBgn0004133|UniProtKB=A1Z714 A1Z714 blow PTHR23180:SF399 CENTAURIN/ARF BLOWN FUSE, ISOFORM A-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 DROME|FlyBase=FBgn0035996|UniProtKB=Q9VSZ2 Q9VSZ2 Dmel\CG3448 PTHR28559:SF1 DNA REPAIR PROTEIN XRCC4 RE59279P metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;response to radiation#GO:0009314;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;DNA repair complex#GO:1990391;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DROME|FlyBase=FBgn0031041|UniProtKB=Q9VWF7 Q9VWF7 Pstk PTHR20873:SF0 L-SERYL-TRNA(SEC) KINASE L-SERYL-TRNA(SEC) KINASE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;tRNA binding#GO:0000049;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 DROME|FlyBase=FBgn0017430|UniProtKB=P92204 P92204 Nelf-E PTHR17250:SF0 NEGATIVE ELONGATION FACTOR E NEGATIVE ELONGATION FACTOR E regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DROME|FlyBase=FBgn0030052|UniProtKB=A0A6H2EDG9 A0A6H2EDG9 Dmel\CG12065 PTHR47705:SF1 AGAP000321-PA WINGED HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN DROME|FlyBase=FBgn0051989|UniProtKB=Q9VMQ4 Q9VMQ4 Cap-D3 PTHR14222:SF1 CONDENSIN CONDENSIN-2 COMPLEX SUBUNIT D3 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 sexual reproduction#GO:0019953;nuclear division#GO:0000280;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070 chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;condensin complex#GO:0000796;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 DROME|FlyBase=FBgn0030316|UniProtKB=Q9VYX0 Q9VYX0 Dmel\CG11695 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0014024|UniProtKB=Q9W4D2 Q9W4D2 Rnp4F PTHR15481:SF0 RIBONUCLEIC ACID BINDING PROTEIN S1 LD23870P-RELATED macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0025378|UniProtKB=Q8MRL2 Q8MRL2 EG:9D2.4 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 DROME|FlyBase=FBgn0263220|UniProtKB=M9PHI0 M9PHI0 Hk PTHR43150:SF11 HYPERKINETIC, ISOFORM M HYPERKINETIC, ISOFORM M ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;binding#GO:0005488;transmembrane transporter binding#GO:0044325;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;protein binding#GO:0005515;channel regulator activity#GO:0016247 regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 DROME|FlyBase=FBgn0052574|UniProtKB=Q8IR08 Q8IR08 Twdlalpha PTHR31927:SF2 FI07246P-RELATED-RELATED FI07246P-RELATED structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0030640|UniProtKB=Q9VXV2 Q9VXV2 Dmel\CG6294 PTHR21054:SF2 ZINC METALLOPROTEINASE-RELATED MIP04191P protease#PC00190;metalloprotease#PC00153 DROME|FlyBase=FBgn0038042|UniProtKB=Q9VG77 Q9VG77 Scgbeta PTHR21142:SF2 SARCOGLYCANS BETA-SARCOGLYCAN sarcolemma#GO:0042383;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796 non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0265102|UniProtKB=Q9VSJ6 Q9VSJ6 Oseg1 PTHR12764:SF4 WD REPEAT DOMAIN-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;protein localization to cilium#GO:0061512;intraciliary transport#GO:0042073;cilium assembly#GO:0060271;cellular component organization#GO:0016043;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intraciliary transport particle A#GO:0030991;non-motile cilium#GO:0097730 DROME|FlyBase=FBgn0032603|UniProtKB=Q9VJI1 Q9VJI1 Dmel\CG17928 PTHR16740:SF1 CYTOCHROME B5-RELATED PROTEIN-RELATED CYTOCHROME B5-RELATED PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 DROME|FlyBase=FBgn0288433|UniProtKB=A1Z9R4 A1Z9R4 L PTHR46179:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 423 HOMOLOG transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0024728|UniProtKB=Q8MR31 Q8MR31 Slip1 PTHR15545:SF8 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 SLO-INTERACTING PROTEIN 1 DROME|FlyBase=FBgn0034658|UniProtKB=Q9W2D1 Q9W2D1 Grx1t PTHR45694:SF30 GLUTAREDOXIN 2 GLUTAREDOXIN-2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176 DROME|FlyBase=FBgn0036356|UniProtKB=Q9VU67 Q9VU67 Dmel\CG10222 PTHR21231:SF3 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 DROME|FlyBase=FBgn0039828|UniProtKB=Q9V9Z9 Q9V9Z9 CG1542 PTHR13028:SF0 RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED RRNA-PROCESSING PROTEIN EBP2-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DROME|FlyBase=FBgn0029819|UniProtKB=Q9W462 Q9W462 Usp30 PTHR24006:SF888 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 DROME|FlyBase=FBgn0261983|UniProtKB=Q9VKJ9 Q9VKJ9 l(2)gd1 PTHR13076:SF9 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0037652|UniProtKB=Q8INP9 Q8INP9 Dmel\CG11980 PTHR11215:SF1 METAL DEPENDENT HYDROLASE - RELATED MYG1 EXONUCLEASE hydrolase#PC00121 DROME|FlyBase=FBgn0034105|UniProtKB=A1ZAD2 A1ZAD2 Dmel\CG7755 PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092;oxidoreductase#PC00176 DROME|FlyBase=FBgn0264562|UniProtKB=Q9W539 Q9W539 Hr4 PTHR48092:SF18 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 6 GROUP A MEMBER 1 nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 DROME|FlyBase=FBgn0015774|UniProtKB=Q24568 Q24568 NetB PTHR10574:SF365 NETRIN/LAMININ-RELATED NETRIN-A-RELATED nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;dendrite development#GO:0016358;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;tissue development#GO:0009888;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;anatomical structure development#GO:0048856;system development#GO:0048731 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 DROME|FlyBase=FBgn0028852|UniProtKB=Q9V3I9 Q9V3I9 BG:DS07851.5 PTHR23326:SF35 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252 CCR4-NOT complex#GO:0030014;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 general transcription factor#PC00259;RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0032234|UniProtKB=Q9VKX7 Q9VKX7 gny PTHR12413:SF1 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 DROME|FlyBase=FBgn0042179|UniProtKB=Q9I7T3 Q9I7T3 Ugt305A1 PTHR48043:SF114 EG:EG0003.4 PROTEIN-RELATED IP04436P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 DROME|FlyBase=FBgn0026150|UniProtKB=Q9VJG0 Q9VJG0 ApepP PTHR43763:SF6 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 1 protease#PC00190 DROME|FlyBase=FBgn0034565|UniProtKB=Q9W2P4 Q9W2P4 Dmel\CG15650 PTHR39951:SF1 FI22632P1 FI22632P1 DROME|FlyBase=FBgn0034871|UniProtKB=Q9W1N9 Q9W1N9 Dmel\CG3906 PTHR21163:SF0 PROTEIN G12 GH08205P-RELATED DROME|FlyBase=FBgn0030629|UniProtKB=Q9VXW4 Q9VXW4 Dmel\CG9123 PTHR44675:SF1 PAK1 INTERACTING PROTEIN 1 P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1 kinase inhibitor activity#GO:0019210;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DROME|FlyBase=FBgn0051708|UniProtKB=Q9VLF0 Q9VLF0 DIP-zeta PTHR12231:SF157 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN EPSILON-RELATED cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 synapse organization#GO:0050808;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 DROME|FlyBase=FBgn0030369|UniProtKB=Q9VYQ5 Q9VYQ5 Cyp318a1 PTHR24305:SF224 CYTOCHROME P450 CYTOCHROME P450 313A1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 DROME|FlyBase=FBgn0036237|UniProtKB=Q8MR62 Q8MR62 PhLP2 PTHR45809:SF3 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 2 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 DROME|FlyBase=FBgn0038494|UniProtKB=Q9VEL7 Q9VEL7 beat-IIb PTHR21261:SF6 BEAT PROTEIN BEATEN PATH IIA-RELATED intercellular signal molecule#PC00207 DROME|FlyBase=FBgn0028646|UniProtKB=Q9VA73 Q9VA73 Aralar PTHR45678:SF9 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED ELECTROGENIC ASPARTATE_GLUTAMATE ANTIPORTER ARALAR, MITOCHONDRIAL carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;L-amino acid transmembrane transporter activity#GO:0015179;acidic amino acid transmembrane transporter activity#GO:0015172;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 transmembrane transport#GO:0055085;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carboxylic acid transport#GO:0046942;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;metabolic process#GO:0008152;L-glutamate transmembrane transport#GO:0015813;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;L-glutamate import#GO:0051938;pyridine-containing compound metabolic process#GO:0072524;carboxylic acid transmembrane transport#GO:1905039;nucleoside phosphate metabolic process#GO:0006753;L-alpha-amino acid transmembrane transport#GO:1902475;primary metabolic process#GO:0044238;establishment of localization#GO:0051234;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;dicarboxylic acid transport#GO:0006835;nucleobase-containing compound metabolic process#GO:0006139;nitrogen compound transport#GO:0071705;NAD+ metabolic process#GO:0019674;aspartate transmembrane transport#GO:0015810;organophosphate metabolic process#GO:0019637;L-amino acid transport#GO:0015807 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 secondary carrier transporter#PC00258;transporter#PC00227 DROME|FlyBase=FBgn0035334|UniProtKB=Q9W022 Q9W022 Dmel\CG8993 PTHR43601:SF39 THIOREDOXIN, MITOCHONDRIAL THIOREDOXIN, MITOCHONDRIAL cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 DROME|FlyBase=FBgn0032595|UniProtKB=Q9VJJ1 Q9VJJ1 Dmel\CG17996 PTHR22977:SF5 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DROME|FlyBase=FBgn0035073|UniProtKB=Q9W0Z4 Q9W0Z4 Dmel\CG16896 PTHR19853:SF1 WD REPEAT CONTAINING PROTEIN 3 WDR3 TBC1 DOMAIN FAMILY MEMBER 31 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DROME|FlyBase=FBgn0000964|UniProtKB=M9PG80 M9PG80 tj PTHR10129:SF50 TRANSCRIPTION FACTOR MAF TRAFFIC JAM, ISOFORM C sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 DROME|FlyBase=FBgn0000541|UniProtKB=Q9W0T1 Q9W0T1 E(bx) PTHR45975:SF2 NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF DROME|FlyBase=FBgn0027334|UniProtKB=Q9VR89 Q9VR89 l(1)G0004 PTHR12826:SF13 RIBONUCLEASE Y RNA-BINDING PROTEIN PNO1 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 endoribonuclease#PC00094 DROME|FlyBase=FBgn0087002|UniProtKB=Q9V496 Q9V496 apolpp PTHR23345:SF36 VITELLOGENIN-RELATED APOLIPOPHORINS molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 storage protein#PC00210 DROME|FlyBase=FBgn0039098|UniProtKB=Q9VCK2 Q9VCK2 GILT3 PTHR13234:SF73 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN 2-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 DROME|FlyBase=FBgn0262112|UniProtKB=Q9VAH3 Q9VAH3 sro PTHR43313:SF65 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C SHORT-CHAIN DEHYDROGENASE_REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 DROME|FlyBase=FBgn0030431|UniProtKB=Q9VYI5 Q9VYI5 Flad1 PTHR23293:SF9 FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE BIFUNCTIONAL FAD DIPHOSPHATASE_FAD SYNTHASE nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;flavin-containing compound metabolic process#GO:0042726;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 metabolite interconversion enzyme#PC00262;transferase#PC00220 Flavin biosynthesis#P02741>FAD synthetase#P02936 DROME|FlyBase=FBgn0038202|UniProtKB=A0A126GUT7 A0A126GUT7 Dmel\CG12402 PTHR13318:SF190 PARTNER OF PAIRED, ISOFORM B-RELATED PARTNER OF PAIRED, ISOFORM B protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 DROME|FlyBase=FBgn0037634|UniProtKB=Q9VHL0 Q9VHL0 hng2 PTHR12243:SF64 MADF DOMAIN TRANSCRIPTION FACTOR DORSAL INTERACTING PROTEIN 3-RELATED regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 DROME|FlyBase=FBgn0027866|UniProtKB=Q9V468 Q9V468 CG9776 PTHR15577:SF2 ZINC FINGER CONTAINING PROTEIN ZINC FINGER PROTEIN 318 negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DROME|FlyBase=FBgn0034131|UniProtKB=A1ZAG7 A1ZAG7 Dmel\CG15712 PTHR21163:SF0 PROTEIN G12 GH08205P-RELATED DROME|FlyBase=FBgn0260049|UniProtKB=Q9VU68 Q9VU68 flr PTHR19856:SF8 WD-REPEATCONTAINING PROTEIN WDR1 WD REPEAT-CONTAINING PROTEIN 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;developmental process#GO:0032502;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;protein-containing complex disassembly#GO:0032984;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;protein-containing complex organization#GO:0043933;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;cellular component disassembly#GO:0022411;striated muscle cell development#GO:0055002 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 DROME|FlyBase=FBgn0053108|UniProtKB=Q9VCE8 Q9VCE8 CG33108 PTHR28631:SF1 UPF0692 PROTEIN C19ORF54 ACTIN MATURATION PROTEASE catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;aminopeptidase activity#GO:0004177 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 DROME|FlyBase=FBgn0052834|UniProtKB=A0A0B4JCV5 A0A0B4JCV5 CG9898 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0025835|UniProtKB=A8JUS7 A8JUS7 Dmel\CG17707 PTHR11161:SF69 O-ACYLTRANSFERASE NOSE RESISTANT-TO-FLUOXETINE PROTEIN N-TERMINAL DOMAIN-CONTAINING PROTEIN acyltransferase#PC00042 DROME|FlyBase=FBgn0010425|UniProtKB=P35005 P35005 epsilonTry PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 DROME|FlyBase=FBgn0033471|UniProtKB=Q7JZ37 Q7JZ37 Dmel\CG12134 PTHR22889:SF0 WD REPEAT-CONTAINING PROTEIN 89 WD REPEAT-CONTAINING PROTEIN 89 DROME|FlyBase=FBgn0051008|UniProtKB=Q8IMH2 Q8IMH2 Dmel\CG31008 PTHR13523:SF2 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DROME|FlyBase=FBgn0036629|UniProtKB=Q9VV59 Q9VV59 GluRS-m PTHR43311:SF2 GLUTAMATE--TRNA LIGASE NONDISCRIMINATING GLUTAMYL-TRNA SYNTHETASE EARS2, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 DROME|FlyBase=FBgn0039972|UniProtKB=Q7KWG9 Q7KWG9 Marf1 PTHR14379:SF79 LIMKAIN B LKAP MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1, ISOFORM D protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 DROME|FlyBase=FBgn0031973|UniProtKB=Q9VLU4 Q9VLU4 Spn28Dc PTHR11461:SF342 SERINE PROTEASE INHIBITOR, SERPIN SERINE PROTEASE INHIBITOR 28DC cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191